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Volume 24, Number 1, January, 1965David B. Slautterback Mitochondria in Cardiac Muscle Cells of the Canary and Some Other Birds . . . . 1 P. F. Elbers and P. H. J. T. Ververgaert and R. Demel Tricomplex Fixation of Phospholipids . . 23 Jacques Vincent and Stanislas Haumont and Joseph Roels Microscopic Determination of Bone Phosphorus by Quantitative Autoradiography of Neutron-Activated Sections . . . . . . . . . . . . . . . . 31 B. E. F. Reimann and Joyce C. Lewin and B. E. Volcani Studies on the Biochemistry and Fine Structure of Silica Shell Formation in Diatoms . . . . . . . . . . . . . . . . 39 J. F. David-Ferreira and R. A. Manaker An Electron Microscope Study of the Development of a Mouse Hepatitis Virus in Tissue Culture Cells . . . . . . . . 57 B. E. S. Gunning The Fine Structure of Chloroplast Stroma Following Aldehyde Osmium-Tetroxide Fixation . . . . . . . . . . . . . . . . 79 Patricia C. Baker Fine Structure and Morphogenic Movements in the Gastrula of the Treefrog, Hyla Regilla . . . . . . . . . . . . . . . . 95 F. B. P. Wooding and D. H. Northcote The Fine Structure and Development of the Companion Cell of the Phloem of \bionameAcer Pseudoplatanus . . . . . . 117 Michael N. Sheridan The Fine Structure of the Electric Organ of Torpedo Marmorata . . . . . . . . . . 129 D. W. Gregory and E. C. Cocking The Large-Scale Isolation of Protoplasts from Immature Tomato Fruit . . . . . . . 143 J. Tooze and H. G. Davies Cytolysomes in Amphibian Erythrocytes 146 Patrick Echlin An Apparent Helical Arrangement of Ribosomes in Developing Pollen Mother Cells of Ipomoea Purpurea (L.) Roth . . 150 Joan Argetsinger The Isolation of Ciliary Basal Bodies (Kinetosomes) from \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 154 D. M. Gill An Improved Method for the Isolation of Rat Liver Nuclei by Density Centrifugation . . . . . . . . . . . . . 157
Richard P. Bunge and Mary Bartlett Bunge and Edith R. Peterson An Electron Microscope Study of Cultured Rat Spinal Cord . . . . . . . . . . . . 163 Kiyoshi Hama Some Observations on the Fine Structure of the Lateral Line Organ of the Japanese Sea Eel Lyncozymba Nystromi . . 193 Jane Overton Changes in Cell Fine Structure During Lens Regeneration in \bionameXenopus laevis . . . . . . . . . . . . . . . . . 211 Jacob J. Blum Observations on the Acid Phosphatases of Euglena Gracilis . . . . . . . . . . . . 223 Joachim R. Sommer and Jacob J. Blum Cytochemical Localization of Acid Phosphatases in Euglena Gracilis . . . . 235 Joachim R. Sommer The Ultrastructure of the Pellicle Complex of Euglena Gracilis . . . . . . 253 Norbert M. Kanczak and Joseph I. Krall and E. Russell Hayes and Willard B. Elliott Lysosomal Fractions from Transitional Epithelium . . . . . . . . . . . . . . . 259 Effat Badr Mourad Evidence for Cytoplasmic DNA in Root Cells of Nicotiana . . . . . . . . . . . 267 P. Satir and A. M. Stuart A New Apical Microtubule-Associated Organelle in the Sternal Gland of Zootermopsis Nevadensis (Hagen), Isoptera . . . . . . . . . . . . . . . . 277 Albert W. Sedar and Ronald M. Burde Localization of the Succinic Dehydrogenase System in \bionameEscherichia coli Using Combined Techniques of Cytochemistry and Electron Microscopy . . . . . . . . . . . . . . . 285 A. Gedeon Matoltsy and Paul F. Parakkal Membrane-Coating Granules of Keratinizing Epithelia . . . . . . . . . 297 R. Gerald Suskind Autoradiographic and Cytochemical Evidence for Synthesis of a Lysine-Containing Ribonucleoprotein in Nucleoli Inhibited by Actinomycin D . . 309 Andre B. Borle and William F. Neuman Effects of Parathyroid Hormone on HeLa Cell Cultures . . . . . . . . . . . . . 316 C. Roland Leeson and Thomas S. Leeson An Unusual Arrangement of Ribosomes in Mesenchymal Cells . . . . . . . . . . . 324 Keiichi Oki and Sadaomi Yoshioka and Kiyoharu Hayashi and Masasuke Masuda Mitochondrial Changes Induced by Iron Absorption in the Duodenal Absorptive Cells of Rats . . . . . . . . . . . . . 328 Joseph V. Landau High Hydrostatic Pressure Effects on Amoeba Proteus . . . . . . . . . . . . . 332
A. A. Avakyan and A. F. Byckovsky Ontogenesis of Human Smallpox Virus . . 337 Barbara J. Stevens The Fine Structure of the Nucleolus During Mitosis in the Grasshopper Neuroblast Cell . . . . . . . . . . . . 349 Atsushi Ichikawa Fine Structural Changes in Response to Hormonal Stimulation of the Perfused Canine Pancreas . . . . . . . . . . . . 369 A. V. Grimstone and L. R. Cleveland The Fine Structure and Function of the Contractile Axostyles of Certain Flagellates . . . . . . . . . . . . . . 387 Wolf Prensky and Harold H. Smith The Mechanism of $5$-Aminouracil-Induced Synchrony of Cell Division in \bionameVicia Faba Root Meristems . . . 401 James Cronshaw and G. Benjamin Bouck The Fine Structure of Differentiating Xylem Elements . . . . . . . . . . . . . 415 Awtar Krishan and Robert C. Buck Structure of the Mitotic Spindle in L Strain Fibroblasts . . . . . . . . . . . 433 David J. L. Luck The Influence of Precursor Pool Size on Mitochondrial Composition in Neurospora Crassa . . . . . . . . . . . . . . . . . 445 David J. L. Luck Formation of Mitochondria in Neurospora Crassa . . . . . . . . . . . . . . . . . 461 R. G. Kessel Intranuclear and Cytoplasmic Annulate Lamellae in Tunicate Oocytes . . . . . . 471 R. E. Reichle and J. V. Alexander Multiperforate Septations, Woronin Bodies, and Septal Plugs in Fusarium . . 489 Doreen E. Ashhurst Mitochondrial Particles Seen in Sections 497 R. J. Stephens and R. F. Bils An Atypical Mitochondrial Form in Normal Rat Liver . . . . . . . . . . . . . . . 500 Hilton H. Mollenhauer An Intercisternal Structure in the Golgi Apparatus . . . . . . . . . . . . . . . 504 E. J. Wills Crystalline Structures in the Mitochondria of Normal Human Liver Parenchymal Cells . . . . . . . . . . . 511
Åke Flock and Arndt J. Duvall The Ultrastructure of the Kinocilium of the Sensory Cells in the Inner Ear and Lateral Line Organs . . . . . . . . . . 1 C. M. S. Dass and S. T. Bayley A Structural Study of Rat Liver Ribosomes . . . . . . . . . . . . . . . 9 Lois Withrow Tice and Russell J. Barrnett Diazophthalocyanins As Reagents for Fine Structural Cytochemistry . . . . . . . . 23 Carl M. Feldherr The Effect of the Electron-Opaque Pore Material on Exchanges Through the Nuclear Annuli . . . . . . . . . . . . . 43 R. G. Kessel and H. W. Beams An Unusual Configuration of the Golgi Complex in Pigment-Producing ``Test'' Cells of the Ovary of the Tunicate, Styela . . . . . . . . . . . . . . . . . 55 John R. Coleman and Heinz Herrmann and Barbara Bess Biosynthesis of Collagen and Non-Collagen Protein During Development of the Chick Cornea . . . . . . . . . . 69 G. Benjamin Bouck and James Cronshaw The Fine Structure of Differentiating Sieve Tube Elements . . . . . . . . . . ?? Hans Laufer and Yasukiyo Nakase Developmental Studies of the Dipteran Salivary Gland . . . . . . . . . . . . . 97 Susumu Kishimoto and Irving Lieberman Nuclear Membranes of Cultured Mammalian Cells in the Period Preceding DNA Synthesis . . . . . . . . . . . . . . . 103 Jacques Lipetz and Anthony J. Garro Ionic Effects on Lignification and Peroxidase in Tissue Cultures . . . . . 109 A. Van Harreveld and Jane Crowell and S. K. Malhotra A Study of Extracellular Space in Central Nervous Tissue by Freeze-Substitution . . . . . . . . . . 117 Jack Maniloff and Harold J. Morowitz and Russell J. Barrnett Studies of the Ultrastructure and Ribosomal Arrangements of the Pleuropneumonia-Like Organism A5969 . . 139 Walther Flemming Contributions to the Knowledge of the Cell and Its Vital Processes . . . . . . 3 Patricia Harris Some Observations Concerning Metakinesis in Sea Urchin Eggs . . . . . . . . . . . 73 J. Mol\`e-Bajer Telophase Segregation of Chromosomes and Amitosis . . . . . . . . . . . . . . . . ?? Arthur Forer Local Reduction of Spindle Fiber Birefringence in Living Nephrotoma Suturalis (Loew) Spermatocytes Induced by Ultraviolet Microbeam Irradiation . . 95 R. Bruce Nicklas Chromosome Velocity During Mitosis As a Function of Chromosome Size and Position 119 R. E. Kane The Mitotic Apparatus . . . . . . . . . 137 Edwin W. Taylor The Mechanism of Colchicine Inhibition of Mitosis . . . . . . . . . . . . . . . 145 Y. Hiramoto Further Studies on Cell Division Without Mitotic Apparatus in Sea Urchin Eggs . . 161 S. T. Takats Non-Random Nuclear Orientation During DNA Synthesis in \bionameTradescantia Pollen Grains . . . . . . . . . . . . . 151 Julio M. Frasca and Verta R. Parks A Routine Technique for Double-Staining Ultrathin Sections Using Uranyl and Lead Salts . . . . . . . . . . . . . . . . . 157 Richard M. Eakin Differentiation of Rods and Cones in Total Darkness . . . . . . . . . . . . . 162 Michael Locke The Structure of Septate Desmosomes . . 166 Oswald Hess The Effect of X-Rays on the Functional Structures of the Y Chromosome in Spermatocytes of \bionameDrosophila Hydei . . . . . . . . . . . . . . . . . 169
John Mcd. Tormey Artifactual Localization of Ferritin in the Ciliary Epithelium in Vitro . . . . 1 Ivan L. Cameron Macromolecular Events Leading to Cell Division in \bionameTetrahymena Pyriformis After Removal and Replacement of Required Pyrimidines . . . . . . . . 9 William B. Kinter and T. Hastings Wilson Autoradiographic Study of Sugar and Amino Acid Absorption by Everted Sacs of Hamster Intestine . . . . . . . . . . . 19 Gerald B. Gordon and Leonard R. Miller and Klaus G. Bensch Studies on the Intracellular Digestive Process in Mammalian Tissue Culture Cells . . . . . . . . . . . . . . . . . 41 J. Herbert Taylor Distribution of Tritium-Labeled DNA Among Chromosomes During Meiosis . . . . 57 F. de Balbian Verster and O. Z. Sellinger and J. C. Harkin Morphological and Biochemical Correlates of Cerebral Microsomes . . . . . . . . . 69 Luther E. Franklin Morphology of Gamete Membrane Fusion and of Sperm Entry into Oocytes of the Sea Urchin . . . . . . . . . . . . . . . . . 81 Toshio Nagano Localization of Adenosine Triphosphatase Activity in the Rat Sperm Tail As Revealed by Electron Microscopy . . . . 101 Nirmal Chakravarty Glycolysis in Rat Peritoneal Mast Cells 123 R. E. Stephens Analysis of Muscle Contraction by Ultraviolet Microbeam Disruption of Sarcomere Structure . . . . . . . . . . 129 David S. Maxwell and Lawrence Kruger The Fine Structure of Astrocytes in the Cerebral Cortex and Their Response to Focal Injury Produced by Heavy Ionizing Particles . . . . . . . . . . . . . . . 141 Arthur Karlin The Association of Acetylcholinesterase and Membrane in Subcellular Fractions of the Electric Tissue of Electrophorus . . 159 G. E. Stone and O. L. Miller and D. M. Prescott H$^3$-Thymidine Derivative Pools in Relation to Macronuclear DNA Synthesis in \bionameTetrahymena Pyriformis . . . 171 Jae Kwon Choi Electron Microscopy of Absorption of Tracer Materials by Toad Urinary Bladder Epithelium . . . . . . . . . . . . . . . 175 Jesse E. Sisken and Luciano Morasca Intrapopulation Kinetics of the Mitotic Cycle . . . . . . . . . . . . . . . . . 179 G. Ben-Hayyim and I. Ohad Synthesis of Cellulose by Acetobacter Xylinum . . . . . . . . . . . . . . . . 191 Lawrence Y. Yatsu The Ultrastructure of Cotyledonary Tissue from Gossypium Hirsutum L. Seeds 193 Edward Essner and Alex B. Novikoff and Nelson Quintana Nucleoside Phosphatase Activities in Rat Cardiac Muscle . . . . . . . . . . . . . 201 T. S. Reese Olfactory Cilia in the Frog . . . . . . 209 Eugene J. Hoffman The Nucleic Acids of Basal Bodies Isolated from \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 217 Henry Tedeschi Some Observations on the Permeability of Mitochondria to Sucrose . . . . . . . . 229 Lumiko Niijima and Jean Dan The Acrosome Reaction in Mytilus Edulis 243 Lumiko Niijima and Jean Dan The Acrosome Reaction in Mytilus Edulis 249 Donald D. Hickman and Albert W. Frenkel Observations on the Structure of Rhodospirillum Molischianum . . . . . . 261 Donald D. Hickman and Albert W. Frenkel Observations on the Structure of Rhodospirillum Rubrum . . . . . . . . . 279 K. Blinzinger and N. B. Rewcastle and H. Hager Observations on Prismatic-Type Mitochondria Within Astrocytes of the Syrian Hamster Brain . . . . . . . . . . 293 Sister M. A. McManus and L. E. Roth Fibrillar Differentiation in Myxomycete Plasmodia . . . . . . . . . . . . . . . 305 Richard Davenport and Janice C. Davenport A Cytochemical Study of Cytoplasmic Basic Proteins in the Ascidian Oocyte 319 Naomi Kislev and Hewson Swift and Lawrence Bogorad Nucleic Acids of Chloroplasts and Mitochondria in Swiss Chard . . . . . . 327 Toshiyuki Yamamoto and Kyoji Tasaki and Yoshio Sugawara and Akira Tonosaki Fine Structure of the Octopus Retina . . 345 Hiromichi Nakajima and Robert D. Allen The Changing Pattern of Birefringence in Plasmodia of the Slime Mold, \bionamePhysarum Polycephalum . . . . . 361 P. F. Elbers and P. H. J. T. Ververgaert Electron Microscope and X-Ray Diffraction Studies on a Homologous Series of Saturated Phosphatidylcholines 375 Nirmal K. Das and Elsie P. Siegel and Max Alfert Synthetic Activities During Spermatogenesis in the Locust . . . . . 387 Arthur M. Zimmerman and Ronald C. Rustad Effects of High Pressure on Pinocytosis in Amoeba Proteus . . . . . . . . . . . 397 I. B. Gibbons Reactivation of Glycerinated Cilia from \bionameTetrahymena Pyriformis . . . . . 400 Toyoko Ishikawa and Yen Fen Pei Intramitochondrial Glycogen Particles in Rat Retinal Receptor Cells . . . . . . . 402 John H. Venable and Richard Coggeshall A Simplified Lead Citrate Stain for Use in Electron Microscopy . . . . . . . . . 407 Stephen L. Wolfe Isolated Microtubules . . . . . . . . . 408
Arthur Hess Developmental Changes in the Structure of the Synapse on the Myelinated Cell Bodies of the Chicken Ciliary Ganglion 1 Gene A. Morrill and Adele B. Kostellow Phospholipid and Nucleic Acid Gradients in the Developing Amphibian Embryo . . . 21 R. E. Kane and Arthur Forer The Mitotic Apparatus . . . . . . . . . 31 Nancy L. Trotter Electron-Opaque, Lipid-Containing Bodies in Mouse Liver at Early Intervals After Partial Hepatectomy and Sham Operation 41 Edward S. Reynolds Liver Parenchymal Cell Injury . . . . . 53 L. Kolehmainen and H. Zech and D. von Wettstein The Structure of Cells During Tobacco Mosaic Virus Reproduction . . . . . . . 77 Yasuo Hotta and Herbert Stern Inducibility of Thymidine Kinase by Thymidine As a Function of Interphase Stage . . . . . . . . . . . . . . . . . 99 D. C. Swartzendruber and M. G. Hanna Electron Microscopic Autoradiography of Germinal Center Cells in Mouse Spleen 109 Lois W. Tice and David S. Smith The Localization of Myofibrillar ATP Ase Activity in the Flight Muscles of the Blowfly, \bionameCalliphora Erythrocephala . . . . . . . . . . . . . 121 Elton Stubblefield Quantitative Tritium Autoradiography of Mammalian Chromosomes . . . . . . . . . 137 Leon Weiss and Alan C. Aisenberg An Electron Microscope Study of Lymphatic Tissue in Runt Disease . . . . 149 Frank S. Labella and Madhu Sanwal Isolation of Nerve Endings from the Posterior Pituitary Gland . . . . . . . 179 Richard M. Hays and Bayla Singer and Sasha Malamed The Effect of Calcium Withdrawal on the Structure and Function of the Toad Bladder . . . . . . . . . . . . . . . . 195 Lee D. Peachey The Sarcoplasmic Reticulum and Transverse Tubules of the Frog's Sartorius . . . . . . . . . . . . . . . 209 Philip W. Brandt and John P. Reuben and Lucien Girardier and Harry Grundfest Correlated Morphological and Physiological Studies on Isolated Single Muscle Fibers . . . . . . . . . . . . . 233 Maria Pia Viola-Magni Changes in the DNA Content of Adrenal Medulla Nuclei of Rats Intermittently Exposed to Cold . . . . . . . . . . . . 415 Huai-San Lin Microcylinders Within Mitochondrial Cristae in the Rat Pinealocyte . . . . . 435 Richard G. Christiansen and John M. Marshall A Study of Phagocytosis in the Ameba Chaos Chaos . . . . . . . . . . . . . . 443 Maria A. Rudzinska The Fine Structure and Function of the Tentacle in \bionameTokophrya Infusionum 459 S. Shibko and J. Pangborn and A. L. Tappel Studies on the Release of Lysosomal Enzymes from Kidney Lysosomes . . . . . 479 P. B. Herdson and J. P. Kaltenbach Electron Microscope Studies on Enzyme Activity and the Isolation of Thiohydantoin-Induced Myelin Figures in Rat Liver . . . . . . . . . . . . . . . 485 Jack Rosenbluth Ultrastructural Organization of Obliquely Striated Muscle Fibers in Ascaris Lumbricoides . . . . . . . . . . 495 D. H. Williamson The Timing of Deoxyribonucleic Acid Synthesis in the Cell Cycle of \bionameSaccharomyces Cerevisiae . . . . 517 Robert Love and Mario V. Fernandes Cytological and Cytochemical Studies of Green Monkey Kidney Cells Infected in Vitro with Simian Virus 40 . . . . . . . 529 Daniel Szollosi Extrusion of Nucleoli from Pronuclei of the Rat . . . . . . . . . . . . . . . . 545 Daniel S. Friend The Fine Structure of Brunner's Glands in the Mouse . . . . . . . . . . . . . . 563 J. W. Combs and D. Lagunoff and E. P. Benditt Differentiation and Proliferation of Embryonic Mast Cells of the Rat . . . . 577 Bruce K. Wetzel and Samuel S. Spicer and Seymour H. Wollman Changes in Fine Structure and Acid Phosphatase Localization in Rat Thyroid Cells Following Thyrotropin Administration . . . . . . . . . . . . . 593 Dale M. Steffensen and William F. Sheridan Incorporation of H$^3$-Thymidine into Chloroplast DNA of Marine Algae . . . . 619 Sten Orrenius and Jan L. E. Ericsson and Lars Ernster Phenobarbital-Induced Synthesis of the Microsomal Drug-Metabolizing Enzyme System and Its Relationship to the Proliferation of Endoplasmic Membranes 627 John A. Parsons Mitochondrial Incorporation of Tritiated Thymidine in \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 641 M. Colonnier On the Nature of Intranuclear Rods . . . 646 Shuichi Karasaki Intranuclear Crystal Within the Phagocytes of the Ovary of \bionameArbacia Punctulata . . . . . . . 654
J. G. Lafontaine A Light and Electron Microscope Study of Small, Spherical Nuclear Bodies in Meristematic Cells of \bionameAllium Cepa, \bionameVicia Faba, and \bionameRaphanus Sativus . . . . . . . . 1 M. Atlas and V. P. Bond The Cell Generation Cycle of the Eleven-Day Mouse Embryo . . . . . . . . 19 R. M. Hicks The Fine Structure of the Transitional Epithelium of Rat Ureter . . . . . . . . 25 Barbara Stay Protein Uptake in the Oocytes of the Cecropia Moth . . . . . . . . . . . . . 49 Catherine A. Smith and Grant L. Rasmussen Degeneration in the Efferent Nerve Endings in the Cochlea After Axonal Section . . . . . . . . . . . . . . . . 63 Bryce L. Munger The Intraepidermal Innervation of the Snout Skin of the Opossum . . . . . . . 79 Milton W. Brightman The Distribution Within the Brain of Ferritin Injected into Cerebrospinal Fluid Compartments . . . . . . . . . . . 99 James E. Trosko and Sheldon Wolff Strandedness of \bionameVicia Faba Chromosomes As Revealed by Enzyme Digestion Studies . . . . . . . . . . . 125 Elizabeth H. Leduc and S. J. Holt Hydroxypropyl Methacrylate, a New Water-Miscible Embedding Medium for Electron Microscopy . . . . . . . . . . 137 Steven Edward Kornguth and John Walberg Anderson Localization of a Basic Protein in the Myelin of Various Species with the Aid of Fluorescence and Electron Microscopy 157 S. Granick and Richard D. Levere The Intracellular Localization of Heme by a Fluorescence Technique . . . . . . 167 Francis S. Greenspan and Judy R. Hargadine The Intracellular Localization of Pituitary Thyrotropic Hormone . . . . . 177 Jack Van't Hof and A. H. Sparrow Radiation Effects on the Growth Rate and Cell Population Kinetics of Actively Growing and Dormant Roots of \bionameTradescantia Paludosa . . . . . 187 Maurice M. Black and Hudson R. Ansley Antigen-Induced Changes in Lymphoid Cell Histones . . . . . . . . . . . . . . . . 201 J. Tooze An Investigation by Electron Microscopy of the Nucleoside Phosphatase Activity of Amphibian and Mammalian Erythrocytes 209 Pierre Baudhuin and Henri Beaufay and Christian de Duve Combined Biochemical and Morphological Study of Particulate Fractions from Rat Liver . . . . . . . . . . . . . . . . . 219 Dino Merlini and Felice Caramia Effect of Dehydroascorbic Acid on the Islets of Langerhans of the Rat Pancreas 245 Marilyn G. Farquhar and George E. Palade Cell Junctions in Amphibian Skin . . . . 263 John F. Aronson The Use of Fluorescein-Labeled Heavy Meromyosin for the Cytological Demonstration of Actin . . . . . . . . . 293 E. L. Benedetti and P. Emmelot Electron Microscopic Observations on Negatively Stained Plasma Membranes Isolated from Rat Liver . . . . . . . . 299 G. Giménez-Martín and A. González-Fernández and J. F. López-Sáez A New Method of Labeling Cells . . . . . 305 Michael K. Reedy Section Staining for Electron Microscopy 309
Zbigniew Srebro The Ultrastructure of Gliosomes in the Brains of Amphibia . . . . . . . . . . . 313 Helen J. Ramsey Fine Structure of the Surface of the Cerebral Cortex of Human Brain . . . . . 323 Joseph Pick The Fine Structure of Sympathetic Neurons in X-Irradiated Frogs . . . . . 335 Miro Brzin and Wolf-Dietrich Dettbarn and Philip Rosenberg and David Nachmansohn Cholinesterase Activity Per Unit Surface Area of Conducting Membranes . . . . . . 353 E. Gantt and S. F. Conti The Ultrastructure of Porphyridium Cruentum . . . . . . . . . . . . . . . . 365 A. A. Hadjiolov and Z. S. Tencheva and A. G. Bojadjieva-Mikhailova Isolation and Some Characteristics of Cell Nuclei from Brain Cortex of Adult Cat . . . . . . . . . . . . . . . . . . 383 Sarah P. Gibbs and W. R. Sistrom and Patricia B. Worden The Photosynthetic Apparatus of Rhodospirillum Molischianum . . . . . . 395 Laura Garnjobst and J. F. Wilson and E. L. Tatum Studies on a Cytoplasmic Character in Neurospora Crassa . . . . . . . . . . . 413 E. G. Diacumakos and L. Garnjobst and E. L. Tatum A Cytoplasmic Character in Neurospora Crassa . . . . . . . . . . . . . . . . . 427 David S. Smith and J. E. Treherne The Electron Microscopic Localization of Cholinesterase Activity in the Central Nervous System of an Insect, \bionamePeriplaneta Americana L. . . . . 445 Arthur Hess The Sarcoplasmic Reticulum, the T System, and the Motor Terminals of Slow and Twitch Muscle Fibers in the Garter Snake . . . . . . . . . . . . . . . . . 467 Sally G. Page A Comparison of the Fine Structures of Frog Slow and Twitch Muscle Fibres . . . 477 Filiberto Giacomelli and Joseph Wiener and David Spiro Cytological Alterations Related to Stimulation of the \bionameZona Glomerulosa of the Adrenal Gland . . . . 499 T. C. Hsu and Frances E. Arrighi and Robert R. Klevecz and B. R. Brinkley The Nucleoli in Mitotic Divisions of Mammalian Cells in Vitro . . . . . . . . 539 R. Gustafsson and J. R. Tata and O. Lindberg and L. Ernster The Relationship Between the Structure and Activity of Rat Skeletal Muscle Mitochondria After Thyroidectomy and Thyroid Hormone Treatment . . . . . . . 555 Jack Rosenbluth Ultrastructure of Somatic Muscle Cells in Ascaris Lumbricoides . . . . . . . . 579 Lester Packer and Paul-andré Siegenthaler and Park S. Nobel Light-Induced Volume Changes in Spinach Chloroplasts . . . . . . . . . . . . . . 593 Raymond G. Murray and Assia S. Murray and Anthony Pizzo The Fine Structure of Mitosis in Rat Thymic Lymphocytes . . . . . . . . . . . 601 Graham Hoyle and James H. McAlear and Allen Selverston Mechanism of Supercontraction in a Striated Muscle . . . . . . . . . . . . 621 K. Seraydarian and W. F. H. M. Mommaerts Density Gradient Separation of Sarcotubular Vesicles and Other Particulate Constituents of Rabbit Muscle . . . . . . . . . . . . . . . . . 641 Philip Fitz-James and Ronald Hancock The Initial Structural Lesion of Penicillin Action in Bacillus Megaterium 657 W. E. Stehbens and M. D. Silver Unusual Development of Basement Membrane About Small Blood Vessels . . . . . . . 669 Glen B. Haydon and D. Alice Taylor Microtubules in Hamster Platelets . . . 673 David M. Phillips An Ordered Filamentous Component in Sciara (Diptera) Salivary Gland Cell Nuclei . . . . . . . . . . . . . . . . . 677
Alexander Eichholz and Robert K. Crane Studies on the Organization of the Brush Border in Intestinal Epithelial Cells 687 Jane Overton and Alexander Eichholz and Robert K. Crane Studies on the Organization of the Brush Border in Intestinal Epithelial Cells 693 I. R. Gibbons An Effect of Adenosine Triphosphate on the Light Scattered by Suspensions of Cilia . . . . . . . . . . . . . . . . . 707 Sten Orrenius On the Mechanism of Drug Hydroxylation in Rat Liver Microsomes . . . . . . . . 713 Sten Orrenius Further Studies on the Induction of the Drug-Hydroxylating Enzyme System of Liver Microsomes . . . . . . . . . . . . 725 Leonard Weiss Studies on Cell Deformability . . . . . 735 B. Thorell and B. Chance and V. Legallais Microspectrophotometry of Cytochromes in the Single Cell at Room and Liquid Nitrogen Temperatures . . . . . . . . . 741 John F. Woods and George Nichols Collagenolytic Activity in Rat Bone Cells . . . . . . . . . . . . . . . . . 747 T. Samorajski and J. M. Ordy and J. R. Keefe The Fine Structure of Lipofuscin Age Pigment in the Nervous System of Aged Mice . . . . . . . . . . . . . . . . . . 779 Maurice M. Black and Hudson R. Ansley Antigen-Induced Changes in Lymphoid Cell Histones . . . . . . . . . . . . . . . . 797 Peter Satir Studies on Cilia . . . . . . . . . . . . 805 Björn A. Afzelius The Occurrence and Structure of Microbodies . . . . . . . . . . . . . . 835 Ivan L. Cameron and E. Ernest Guile Nucleolar and Biochemical Changes During Unbalanced Growth of \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 845 M. Locke and J. V. Collins The Structure and Formation of Protein Granules in the Fat Body of an Insect 857 Henry deF. Webster and Adelbert Ames Reversible and Irreversible Changes in the Fine Structure of Nervous Tissue During Oxygen and Glucose Deprivation 885 A. Kent Christensen The Fine Structure of Testicular Interstitial Cells in Guinea Pigs . . . 911 Shuichi Karasaki Electron Microscopic Examination of the Sites of Nuclear RNA Synthesis During Amphibian Embryogenesis . . . . . . . . 937 P. O'B. Montgomery and James E. Cook and David Karney Ultraviolet Microbeam Irradiation in Living Cell Membranes . . . . . . . . . 959 Una Smith and David S. Smith A Microtubular Complex in the Epidermal Nucleus of an Insect, Carausius Morosus 961 J. J. Wolken and G. J. Gallik The Compound Eye of a Crustacean, Leptodora Kindtii . . . . . . . . . . . 968 Martha E. Fedorko and James G. Hirsch Crystalloid Structure in Granules of Guinea Pig Basophils and Human Mast Cells . . . . . . . . . . . . . . . . . 973 Nobuko O. Kuhn and Margaret L. Olivier Ultrastructure of the Hepatic Sinusoid of the Goat Capra Hircus . . . . . . . . 977
Umberto Muscatello and Alfredo Margreth and Massimo Aloisi On the Differential Response of Sarcoplasm and Myoplasm to Denervation in Frog Muscle . . . . . . . . . . . . . 1 Frits Carlsen and Franklin Fuchs and Gustav G. Knappeis Contractility and Ultrastructure in Glycerol-Extracted Muscle Fibers . . . . 25 Frits Carlsen and Franklin Fuchs and Gustav G. Knappeis Contractility and Ultrastructure in Glycerol-Extracted Muscle Fibers . . . . 35 R. Wiesner and G. Acs and E. Reich and A. Shafiq Degradation of Ribonucleic Acid in Mouse Fibroblasts Treated with Actinomycin . . 47 Albert W. Sedar and Ronald M. Burde The Demonstration of the Succinic Dehydrogenase System in Bacillus Subtilis Using Tetranitro-Blue Tetrazolium Combined with Techniques of Electron Microscopy . . . . . . . . . . 53 Kiyoteru Tokuyasu and Otto H. Scherbaum Ultrastructure of Mucocysts and Pellicle of \bionameTetrahymena Pyriformis . . . 67 Russell Ross and Earl P. Benditt Wound Healing and Collagen Formation . . 83 Joseph Wiener and David Spiro and Werner R. Loewenstein Ultrastructure and Permeability of Nuclear Membranes . . . . . . . . . . . 107 W. Arnoldo Levy and Ivan Herzog and Kunihiko Suzuki and Robert Katzman and Labe Scheinberg Method for Combined Ultrastructural and Biochemical Analysis of Neural Tissue 119 Jack L. Pate and Erling J. Ordal The Fine Structure of Two Unusual Stalked Bacteria . . . . . . . . . . . . 133 Roderic B. Park Substructure of Chloroplast Lamellae . . 151 Elsi R. Suter and Guido Majno Passage of Lipid Across Vascular Endothelium in Newborn Rats . . . . . . 163 Jack Van't Hof Cell Population Kinetics of Excised Roots of Pisum Sativum . . . . . . . . . 179 Donald E. Rounds and Robert S. Olson and Fred M. Johnson The Laser As a Potential Tool for Cell Research . . . . . . . . . . . . . . . . 191 Bernard P. Lane Alterations in the Cytologic Detail of Intestinal Smooth Muscle Cells in Various Stages of Contraction . . . . . 199 George E. Palade and Marilyn G. Farquhar A Special Fibril of the Dermis . . . . . 215 Charles F. Simpson and J. M. Kling and F. C. Neal The Nature of Bands in Parasitized Bovine Erythrocytes . . . . . . . . . . 225 W. Leene and Woutera van Iterson Tetranitro-Blue Tetrazolium Reduction in Bacillus Subtilis . . . . . . . . . . . 237 W. Leene and Woutera van Iterson Tetranitro-Blue Tetrazolium Reduction in Proteus Vulgaris . . . . . . . . . . . . 241 Ronald Piddington and A. A. Moscona Correspondence Between Glutamine Synthetase Activity and Differentiation in the Embryonic Retina in Situ and in Culture . . . . . . . . . . . . . . . . 247 Geraldine F. Gauthier and Helen A. Padykula Cytochemical Studies of Adenosine Triphosphatase Activity in the Sarcoplasmic Reticulum . . . . . . . . . 252
Lloyd M. Beidler and Ronald L. Smallman Renewal of Cells Within Taste Buds . . . 263 Paul F. Kruse and Ed Miedema Production and Characterization of Multiple-Layered Populations of Animal Cells . . . . . . . . . . . . . . . . . 273 Albert A. Barber and Warren W. Harris and George M. Padilla Studies of Native Glycogen Isolated from Synchronized \bionameTetrahymena Pyriformis (Hsm) . . . . . . . . . . . . 281 John A. Terzakis The Nucleolar Channel System of Human Endometrium . . . . . . . . . . . . . . 293 A. T. Miller and D. M. Hale and K. D. Alexander Histochemical Studies on the Uptake of Horseradish Peroxidase by Rat Kidney Slices . . . . . . . . . . . . . . . . . 305 Michael E. Lamm and Lillian Childers and Merrill K. Wolf Studies on Nucleic Acid Metachromasy . . 313 Ned Feder and Merrill K. Wolf Studies on Nucleic Acid Metachromasy . . 327 J. E. Cummins and E. N. Brewer and H. P. Rusch The Effect of Actidione on Mitosis in the Slime Mold \bionamePhysarum Polycephalum . . . . . . . . . . . . . . 337 Paul B. Green Pathways of Cellular Morphogenesis . . . 343 Jean C. Edelman and P. Michael Edelman and Karl M. Knigge and Irving L. Schwartz Isolation of Skeletal Muscle Nuclei . . 365 David S. Smith The Organization of Flight Muscle in an Aphid, \bionameMegoura Viciae (Homoptera) . . . . . . . . . . . . . . 379 David M. Phillips and Hewson Swift Cytoplasmic Fine Structure of Sciara Salivary Glands . . . . . . . . . . . . 395 B. R. Brinkley The Fine Structure of the Nucleolus in Mitotic Divisions of Chinese Hamster Cells in Vitro . . . . . . . . . . . . . 411 Howard T. Bonnett and Eldon H. Newcomb Polyribosomes and Cisternal Accumulations in Root Cells of Radish 423 Manfred Girbardt Lebendnachweis Von Einzelelementen Des Endoplasmatischen Retikulums. (German) [Proof of Single Elements of the Endoplasmic Reticulum] . . . . . . . . . 433 Theodor Koller Mounting of Ultrathin Sections with the Aid of an Electrostatic Field . . . . . 441 J. W. Fristrom and H. K. Mitchell The Preparative Isolation of Imaginal Discs from Larvae of \bionameDrosophila Melanogaster . . . . . . . . . . . . . . 445 Bruce E. Bassett and Lester Packer Response of Isolated Lysosomes to Vitamin A . . . . . . . . . . . . . . . 448
Yasuo Hotta and Alix Bassel and Herbert Stern Nuclear DNA and Cytoplasmic DNA from Tissues of Higher Plants . . . . . . . . 451 David G. McConnell The Isolation of Retinal Outer Segment Fragments . . . . . . . . . . . . . . . 459 Susumu Ito The Enteric Surface Coat on Cat Intestinal Microvilli . . . . . . . . . 475 Jiro Matsumoto Studies on Fine Structure and Cytochemical Properties of Erythrophores in Swordtail, Xiphophorus Helleri, with Special Reference to Their Pigment Granules (Pterinosomes) . . . . . . . . 493 Fenton Schaffner and Philip Felig Changes in Hepatic Structure in Rats Produced by Breathing Pure Oxygen . . . 505 Charles J. Flickinger The Fine Structure of the Nuclei of \bionameTetrahymena Pyriformis Throughout the Cell Cycle . . . . . . . 519 Henry Z. Movat and William J. Weiser and Michael F. Glynn and James F. Mustard Platelet Phagocytosis and Aggregation 531 A. Di Marco and R. Silvestrini and S. Di Marco and T. Dasdia Inhibiting Effect of the New Cytotoxic Antibiotic Daunomycin on Nucleic Acids and Mitotic Activity of HeLa Cells . . . 545 Richard A. Ellis Fine Structure of the Myoepithelium of the Eccrine Sweat Glands of Man . . . . 551 Terry C. Johnson and John J. Holland Ribonucleic Acid and Protein Synthesis in Mitotic HeLa Cells . . . . . . . . . 565 Eldon H. Newcomb and Howard T. Bonnett Cytoplasmic Microtubule and Wall Microfibril Orientation in Root Hairs of Radish . . . . . . . . . . . . . . . . . 575 Corrado M. Baglio and Emmanuel Farber Reversal by Adenine of the Ethionine-Induced Lipid Accumulation in the Endoplasmic Reticulum of the Rat Liver . . . . . . . . . . . . . . . . . 591 Nancy J. Lane and Alex B. Novikoff Effects of Arginine Deprivation, Ultraviolet Radiation, and X-Radiation on Cultured Kb Cells . . . . . . . . . . 603 Carl F. T. Mattern and Helen D. Park and Wendell A. Daniel Electron Microscope Observations on the Structure and Discharge of the Stenotele of Hydra . . . . . . . . . . . . . . . . 621 R. E. Stephens Anomalous Contraction of Invertebrate Striated Muscle . . . . . . . . . . . . 639 Eric Holtzman and Alex B. Novikoff Lysosomes in the Rat Sciatic Nerve Following Crush . . . . . . . . . . . . 651 Sheppard M. Walker and G. Randolph Schrodt Continuity of the T System with the Sarcolemma in Rat Skeletal Muscle Fibers 671 Kaneatsu Miyamoto and Seiichi Matsumoto The Nature of the Negri Body . . . . . . 677 D. Nash and W. Plaut On the Presence of DNA in Larval Salivary Gland Nucleoli in \bionameDrosophila Melanogaster . . . . 682
N. Böhm and W. Sandritter Feulgen Hydrolysis of Normal Cells and Mouse Ascites Tumor Cells . . . . . . . 1 Maria Pia Viola-Magni A Radioautographic Study with H$^3$-Thymidine on Adrenal Medulla Nuclei of Rats Intermittently Exposed to Cold . . . . . . . . . . . . . . . . . . 9 R. M. Hicks The Permeability of Rat Transitional Epithelium . . . . . . . . . . . . . . . 21 G. G. Carmichael and H. M. Fullmer The Fine Structure of the Oxytalan Fiber 33 J. C. Thaemert Ultrastructural Interrelationships of Nerve Processes and Smooth Muscle Cells in Three Dimensions . . . . . . . . . . 37 Douglas E. Kelly Fine Structure of Desmosomes, Hemidesmosomes, and an Adepidermal Globular Layer in Developing Newt Epidermis . . . . . . . . . . . . . . . 51 Jack Rosenbluth Redundant Myelin Sheaths and Other Ultrastructural Features of the Toad Cerebellum . . . . . . . . . . . . . . . 73 Richard E. Coggeshall A Fine Structural Analysis of the Epidermis of the Earthworm, \bionameLumbricus Terrestris L . . . . . 95 David S. Smith The Organization of Flight Muscle Fibers in the Odonata . . . . . . . . . . . . . 109 Leonard Merkow and Joseph Leighton Increased Numbers of Annulate Lamellae in Myocardium of Chick Embryos Incubated at Abnormal Temperatures . . . . . . . . 127 J. D. Regan and E. H. Y. Chu A Convenient Method for Assay of DNA Synthesis in Synchronized Human Cell Cultures . . . . . . . . . . . . . . . . 139
John R. Kennedy The Effect of Strychnine and Light on Pigmentation in Blepharisma Undulans Stein . . . . . . . . . . . . . . . . . 145 A. C. Taylor Microtubules in the Microspikes and Cortical Cytoplasm of Isolated Cells . . 155 William P. Cunningham and D. James Morré and H. H. Mollenhauer Structure of Isolated Plant Golgi Apparatus Revealed by Negative Staining 169 Sten Orrenius and Jan L. E. Ericsson Enzyme-Membrane Relationship in Phenobarbital Induction of Synthesis of Drug-Metabolizing Enzyme System and Proliferation of Endoplasmic Membranes 181 F. A. Muckenthaler and A. P. Mahowald DNA Synthesis in the Ooplasm of \bionameDrosophila Melanogaster . . . . 199 Michael J. Droller and Thomas F. Roth An Electron Microscope Study of Yolk Formation During Oogenesis in Lebistes Reticulatus Guppyi . . . . . . . . . . . 209 John Seed The Synthesis of DNA, RNA, and Nuclear Protein in Normal and Tumor Strain Cells 233 John Seed The Synthesis of DNA, RNA, and Nuclear Protein in Normal and Tumor Strain Cells 249 John Seed The Synthesis of DNA, RNA, and Nuclear Protein in Normal and Tumor Strain Cells 257 John Seed The Synthesis of DNA, RNA, and Nuclear Protein in Normal and Tumor Strain Cells 263 Dorothy Ford Bainton and Marilyn G. Farquhar Origin of Granules in Polymorphonuclear Leukocytes . . . . . . . . . . . . . . . 277 Jerry S. Sutton and Leon Weiss Transformation of Monocytes in Tissue Culture into Macrophages, Epithelioid Cells, and Multinucleated Giant Cells 303 Geraldine F. Gauthier and Helen A. Padykula Cytological Studies of Fiber Types in Skeletal Muscle . . . . . . . . . . . . 333 Masamichi Aikawa and Peter K. Hepler and Clay G. Huff and Helmuth Sprinz The Feeding Mechanism of Avian Malarial Parasites . . . . . . . . . . . . . . . 355 John A. Carney and Arnold L. Brown An Electron Microscope Study of Canine Cardiac Myosin and Some of Its Aggregates . . . . . . . . . . . . . . . 375 Alex M. Landolt and Hans Ris Electron Microscope Studies on Soma-Somatic Interneuronal Junctions in the Corpus Pedunculatum of the Wood Ant (\bionameFormica Lugubris Zett.) . . . . 391 Curtis C. Harris and Charles A. Leone Some Effects of EDTA and Tetraphenylboron on the Ultrastructure of Mitochondria in Mouse Liver Cells . . 405 J. V. Landau High Pressure Effects on Endogenous Adenine Nucleotide Levels in Sea Urchin Eggs Prior to First Cleavage . . . . . . 408
G. Eric Bauer and Arnold W. Lindall and Padmaker K. Dixit and Gordon Lester and Arnold Lazarow Studies on Insulin Biosynthesis . . . . 413 Jean M. Schmidt and R. Y. Stanier The Development of Cellular Stalks in Bacteria . . . . . . . . . . . . . . . . 423 David E. Comings Uridine-$5$-H$^3$ Radioautography of the Human Sex Chromatin Body . . . . . . . . 437 Lester Packer and Park S. Nobel and Elizabeth L. Gross and Howard C. Mel Fractionation of Spinach Chloroplasts by Flow Sedimentation-Electrophoresis . . . 443 Hideyuki Tsukada and Yohichi Mochizuki and Seiki Fujiwara The Nucleoids of Rat Liver Cell Microbodies . . . . . . . . . . . . . . 449 Zipora Dafni and M. Shilo The Cytotoxic Principle of the Phytoflagellate Prymnesium Parvum . . . 461 Joan Abbott and Howard Holtzer The Loss of Phenotypic Traits by Differentiated Cells . . . . . . . . . . 473 T. Samorajski and J. M. Ordy and J. R. Keefe Structural Organization of the Retina in the Tree Shrew (\bionameTupaia Glis) . . 489 Frank A. Pepe Some Aspects of the Structural Organization of the Myofibril As Revealed by Antibody-Staining Methods 505 Lothar Diers On the Plastids, Mitochondria, and Other Cell Constituents During Oögenesis of a Plant . . . . . . . . . . . . . . . . . 527 Martin Hagopian The Myofilament Arrangement in the Femoral Muscle of the Cockroach, Leucophaea Maderae Fabricius . . . . . . 545 Woutera van Iterson The Fine Structure of the Ribonucleoprotein in Bacterial Cytoplasm 563 Eugene E. Emeson and Yutaka Kikkawa and Boris Gueft New Features of Amyloid Found After Digestion with Trypsin . . . . . . . . . 570 T. S. Leeson and C. R. Leeson Osmiophilic Lamellated Bodies and Associated Material in Lung Alveolar Spaces . . . . . . . . . . . . . . . . . 577 Philip M. Lintilhac and R. B. Park Localization of Chlorophyll in Spinach Chloroplast Lamellae by Fluorescence Microscopy . . . . . . . . . . . . . . . 582
Martin J. Griffin and Rody P. Cox Studies on the Mechanism of Hormonal Induction of Alkaline Phosphatase in Human Cell Cultures . . . . . . . . . . 1 R. E. Rasmussen and R. B. Painter Radiation-Stimulated DNA Synthesis in Cultured Mammalian Cells . . . . . . . . 11 R. C. von Borstel and D. M. Prescott and F. J. Bollum Incorporation of Nucleotides into Nuclei of Fixed Cells by DNA Polymerase . . . . 21 B. J. Bryant The Incorporation of Tritium from Thymidine into Proteins of the Mouse . . 29 John W. Greenawalt and Ernesto Carafoli Electron Microscope Studies on the Active Accumulation of Sr$^{++}$ by Rat-Liver Mitochondria . . . . . . . . . 37 E. L. Kuff and W. C. Hymer and E. Shelton and N. E. Roberts The in Vivo Protein Synthetic Activities of Free Versus Membrane-Bound Ribonucleoprotein in a Plasma-Cell Tumor of the Mouse . . . . . . . . . . . . . . 63 Lewis G. Tilney and Yukio Hiramoto and Douglas Marsland Studies on the Microtubules in Heliozoa 77 Ikuko Mizukami and Joseph Gall Centriole Replication . . . . . . . . . 97 H. Dariush Fahimi and Morris J. Karnovsky Cytochemical Localization of Two Glycolytic Dehydrogenases in White Skeletal Muscle . . . . . . . . . . . . 113 C. F. Robinow and J. Marak A Fiber Apparatus in the Nucleus of the Yeast Cell . . . . . . . . . . . . . . . 129 Hans Moor Ultrastrukturen im Zellkern der Bäckerhefe. (German) [Ultrastructures in the cell nucleus of baker's yeast] . . . 153 J. C. Thaemert Ultrastructure of Cardiac Muscle and Nerve Contiguities . . . . . . . . . . . 156 Thomas L. Lentz Intramitochondrial Glycogen Granules in Digestive Cells of Hydra . . . . . . . . 162 R. J. Stein and W. R. Richter and R. A. Zussman and G. Brynjolfsson Ultrastructural Characterization of Daphnia Heart Muscle . . . . . . . . . . 168 Richard D. Penn Ionic Communication Between Liver Cells 171 Vinod C. Shah and Harvard Lyman DNA-Dependent RNA Synthesis in Chloroplasts of Euglena Gracilis . . . . 174 Jacques Padawer Induction of Cellular Movements in Mast Cells by Colchicine Treatment . . . . . 176
A. N. J. Heyn The Microcrystalline Structure of Cellulose in Cell Walls of Cotton, Ramie, and Jute Fibers As Revealed by Negative Staining of Sections . . . . . 181 Abraham Amsterdam and Michael Schramm Rapid Release of the Zymogen Granule Protein by Osmium Tetroxide and Its Retention During Fixation by Glutaraldehyde . . . . . . . . . . . . . 199 Mac Donald Cave Incorporation of Tritium-Labeled Thymidine and Lysine into Chromosomes of Cultured Human Leukocytes . . . . . . . 209 Jane Rearick Shoup The Development of Pigment Granules in the Eyes of Wild Type and Mutant \bionameDrosophila Melanogaster . . . . 223 W. Gerald Robison Microtubules in Relation to the Motility of a Sperm Syncytium in an Armored Scale Insect . . . . . . . . . . . . . . . . . 251 P. Nicolescu and M. Dolivo and C. Rouiller and C. Foroglou-Kerameus The Effect of Deprivation of Glucose on the Ultrastructure and Function of the Superior Cervical Ganglion of the Rat in Vitro . . . . . . . . . . . . . . . . . 267 R. G. Kulka and U. Yalovsky Secretion of $ \alpha $-amylase by the embryonic chick pancreas in vitro . . . 287 Jane Overton Microtubules and Microfibrils in Morphogenesis of the Scale Cells of \bionameEphestia Kühniella . . . . . . . 293 Martha E. Fedorko and James G. Hirsch Cytoplasmic Granule Formation in Myelocytes . . . . . . . . . . . . . . . 307 Daniel S. Friend The Fine Structure of Giardia Muris . . 317 Paul F. Doolin and Wesley J. Birge Ultrastructural Organization of Cilia and Basal Bodies of the Epithelium of the Choroid Plexus in the Chick Embryo 333 Natalia Gabrusewycz-Garcia and Ruth G. Kleinfeld A Study of the Nucleolar Material in Sciara Coprophila . . . . . . . . . . . 347 S. J. Holt and R. Marian Hicks The Importance of Osmiophilia in the Production of Stable Azoindoxyl Complexes of High Contrast for Combined Enzyme Cytochemistry and Electron Microscopy . . . . . . . . . . . . . . . 361 A. B. Acton An Unusual Ciliumlike Process . . . . . 366 J. R. Cook The Synthesis of Cytoplasmic DNA in Synchronized Euglena . . . . . . . . . . 369 Hilton H. Mollenhauer and D. James Morré Tubular Connections Between Dictyosomes and Forming Secretory Vesicles in Plant Golgi Apparatus . . . . . . . . . . . . 373 Brij L. Gupta and Michael J. Berridge A Coat of Repeating Subunits on the Cytoplasmic Surface of the Plasma Membrane in the Rectal Papillae of the Blowfly, \bionameCalliphora Erythrocephala (Meig.), Studied in Situ by Electron Microscopy . . . . . . . . . 376 Luis Biempica Human Hepatic Microbodies with Crystalloid Cores . . . . . . . . . . . 383
Takeshi Utsunomiya and Jay S. Roth Studies on the Function of Intracellular Ribonucleases . . . . . . . . . . . . . 387 Takeshi Utsunomiya and Jay S. Roth Studies on the Function of Intracellular Ribonucleases . . . . . . . . . . . . . 395 Dean H. Hayek and Samuel R. Tipton Respiratory Activity and Maintenance of Cell Suspensions of Rat Liver . . . . . 405 George P. Studzinski and Kay A. O. Ellem Relationship Between RNA Synthesis, Cell Division, and Morphology of Mammalian Cells . . . . . . . . . . . . . . . . . 411 E. Gantt and S. F. Conti Granules Associated with the Chloroplast Lamellae of Porphyridium Cruentum . . . 423 Stanley Bullivant and Adelbert Ames A Simple Freeze-Fracture Replication Method for Electron Microscopy . . . . . 435 David S. Smith The Structure of Intersegmental Muscle Fibers in an Insect, \bionamePeriplaneta Americana L. . . . . . . . . . . . . . . 449 John C. Maisel and Ralph I. Lytle Affinity of Animal Cell Nucleoli for Normal Serum . . . . . . . . . . . . . . 461 Floyd E. Bloom and Russell J. Barrnett Fine Structural Localization of Acetylcholinesterase in Electroplaque of the Electric Eel . . . . . . . . . . . . 475 Arndt J. Duvall and Åke Flock and Jan Wersäll The Ultrastructure of the Sensory Hairs and Associated Organelles of the Cochlear Inner Hair Cell, with Reference to Directional Sensitivity . . . . . . . 497 Ulla Glas and Gunter F. Bahr Quantitative Study of Mitochondria in Rat Liver . . . . . . . . . . . . . . . 507 Alex B. Novikoff and Nelson Quintana and Humberto Villaverde and Regina Forschirm Nucleoside Phosphatase and Cholinesterase Activities in Dorsal Root Ganglia and Peripheral Nerve . . . . . . 525 Carl F. T. Mattern and Wendell A. Daniel The Stomach Cell of Rotifer . . . . . . 547 Carl F. T. Mattern and Wendell A. Daniel The Flame Cell of Rotifer . . . . . . . 552 K. Owen Ash and J. E. Bransford and R. B. Koch Studies on Dispersion of Rabbit Olfactory Cells . . . . . . . . . . . . 554
D. Chapman and D. J. Fluck Physical Studies of Phospholipids . . . 1 Richard D. Estensen and Renato Baserga Puromycin-Induced Necrosis of Crypt Cells of the Small Intestine of Mouse 13 Ewald R. Weibel and Gonzague S. Kistler and Walter F. Scherle Practical Stereological Methods for Morphometric Cytology . . . . . . . . . 23 Leonard Weiss Studies on Cell Deformability . . . . . 39 Oscar K. Reiss Studies of Lung Metabolism . . . . . . . 45 Theodore K. Greenlee and Russell Ross and Jerry L. Hartman The Fine Structure of Elastic Fibers . . 59 Gustav Dallner and Philip Siekevitz and George E. Palade Biogenesis of Endoplasmic Reticulum Membranes . . . . . . . . . . . . . . . 73 Gustav Dallner and Philip Siekevitz and George E. Palade Biogenesis of Endoplasmic Reticulum Membranes . . . . . . . . . . . . . . . 97 Marian Neutra and C. P. Leblond Synthesis of the Carbohydrate of Mucus in the Golgi Complex As Shown by Electron Microscope Radioautography of Goblet Cells from Rats Injected with Glucose-H$^3$ . . . . . . . . . . . . . 119 Marian Neutra and C. P. Leblond Radioautographic Comparison of the Uptake of Galactose-H$^3$ and Glucose-H$^3$ in the Golgi Region of Various Cells Secreting Glycoproteins or Mucopolysaccharides . . . . . . . . . . 137 Antonio Coimbra and C. P. Leblond Sites of Glycogen Synthesis in Rat Liver Cells As Shown by Electron Microscope Radioautography After Administration of Glucose-H$^3$ . . . . . . . . . . . . . 151 A. Lima-de-Faria and M. J. Moses Ultrastructure and Cytochemistry of Metabolic DNA in Tipula . . . . . . . . 177 Peter Pfuderer and D. C. Swartzendruber The Configuration of Isolated Polysomes 193 Graham Hoyle and Patricia Ann McNeill and Benjamin Walcott Nature of Invaginating Tubules in Felderstruktur Muscle Fibers of the Garter Snake . . . . . . . . . . . . . . 197 H. M. Dembitzer and H. I. Hirshfield Some New Cytological Observations in the Heterotrichous Ciliate, Blepharisma . . 201 Atsushi Suganuma Further Studies on the Plasma Membrane of Staphylococcus Aureus . . . . . . . . 208
Maria Pia Viola-Magni An Analysis of DNA Loss and Synthesis in the Rat Adrenal Medulla Nuclei Upon Cold Stimulation . . . . . . . . . . . . . . 213 Bojan Flaks and Paul Bresloff Some Observations on the Fine Structure of the Lutein Cells of X-Irradiated Rat Ovary . . . . . . . . . . . . . . . . . 227 Gordon I. Kaye and Henry O. Wheeler and Robert T. Whitlock and Nathan Lane Fluid Transport in the Rabbit Gallbladder . . . . . . . . . . . . . . 237 Charles R. Hackenbrock Ultrastructural Bases for Metabolically Linked Mechanical Activity in Mitochondria . . . . . . . . . . . . . . 269 Mary G. Wetzel and Bruce K. Wetzel and Samuel S. Spicer Ultrastructural Localization of Acid Mucosubstances in the Mouse Colon with Iron-Containing Stains . . . . . . . . . 299 Wayne Hohman and Harald Schraer The Intracellular Distribution of Calcium in the Mucosa of the Avian Shell Gland . . . . . . . . . . . . . . . . . 317 Peter K. Hepler and Clay G. Huff and Helmuth Sprinz The Fine Structure of the Exoerythrocytic Stages of Plasmodium Fallax . . . . . . . . . . . . . . . . . 333 Marilyn G. Farquhar and George E. Palade Adenosine Triphosphatase Localization in Amphibian Epidermis . . . . . . . . . . 359 John E. Heuser and Carlos F. Doggenweiler The Fine Structural Organization of Nerve Fibers, Sheaths, and Glial Cells in the Prawn, Palaemonetes Vulgaris . . 381 H. Lòvtrup-Rein and B. S. McEwen Isolation and Fractionation of Rat Brain Nuclei . . . . . . . . . . . . . . . . . 405 Yutaka Mishima Melanosomes in Phagocytic Vacuoles in Langerhans Cells . . . . . . . . . . . . 417 Arnold M. Seligman and Hannah L. Wasserkrug and Jacob S. Hanker A New Staining Method (Oto) for Enhancing Contrast of Lipid-Containing Membranes and Droplets in Osmium Tetroxide-Fixed Tissue with Osmiophilic Thiocarbohydrazide (Tch) . . . . . . . . 424 Alan S. Bradley and Steven L. Wissig The Anatomy of Secretion in the Follicular Cell of the Thyroid Gland . . 433 Monique Milhaud and George D. Pappas Postsynaptic Bodies in the Habenula and Interpeduncular Nuclei of the Cat . . . 437 Donald J. Svoboda and Daniel L. Azarnoff Response of Hepatic Microbodies to a Hypolipidemic Agent, Ethyl Chlorophenoxyisobutyrate (Cpib) . . . . 442
Breck Byers Ribosome Crystallization Induced in Chick Embryo Tissues by Hypothermia . . ?? John F. Aronson A Melting Point for the Birefringent Component of Muscle . . . . . . . . . . 453 Mary R. Daniel and J. T. Dingle and Audrey M. Glauert and J. A. Lucy The Action of Excess of Vitamin a Alcohol on the Fine Structure of Rat Dermal Fibroblasts . . . . . . . . . . . 465 David M. Phillips Observations on Spermiogenesis in the Fungus Gnat Sciara Coprophila . . . . . 477 David M. Phillips Fine Structure of \bionameSciara Coprophila Sperm . . . . . . . . . . . . 499 P. Siekevitz and G. E. Palade Distribution of Newly Synthesized Amylase in Microsomal Subfractions of Guinea Pig Pancreas . . . . . . . . . . 519 George M. Healy and Raymond C. Parker An Improved Chemically Defined Basal Medium (Cmrl-1415) for Newly Explanted Mouse Embryo Cells . . . . . . . . . . . 531 George M. Healy and Raymond C. Parker Cultivation of Mammalian Cells in Defined Media with Protein and Nonprotein Supplements . . . . . . . . . 539 Hans A. Went An Indirect Method to Assay for Mitotic Centers in Sand Dollar (\bionameDendraster Excentricus) Eggs 555 T. J. Biscoe and W. E. Stehbens Ultrastructure of the Carotid Body . . . 563 Luciano Zamboni and Daniel R. Mishell and James H. Bell and Manuel Baca Fine Structure of the Human Ovum in the Pronuclear Stage . . . . . . . . . . . . 579 Donald F. Hoelzl Wallach and Virendra B. Kamat and Mitchell H. Gail Physicochemical Differences Between Fragments of Plasma Membrane and Endoplasmic Reticulum . . . . . . . . . 601 R. M. Hicks The Function of the Golgi Complex in Transitional Epithelium . . . . . . . . 623 Elton Stubblefield and B. R. Brinkley Cilia Formation in Chinese Hamster Fibroblasts in Vitro As a Response to Colcemid Treatment . . . . . . . . . . . 645 Raneen Mullins and Reimut Wette On the Statistical Expectation and Evaluation of Centriole Orientations in Cell Profiles . . . . . . . . . . . . . 652 N. J. A. Noorduyn and J. C. H. de Man RNA Synthesis in Rat and Mouse Hepatic Cells As Studied with Light and Electron Microscope Radioautography . . . . . . . 655 Donald F. Hoelzl Wallach and Virendra B. Kamat The Contribution of Sialic Acid to the Surface Charge of Fragments of Plasma Membrane and Endoplasmic Reticulum . . . 660 Emilio Bucciarelli Intranuclear Cisternae Resembling Structures of the Golgi Complex . . . . 664
David M. Prescott The Syntheses of Total Macronuclear Protein, Histone, and DNA During the Cell Cycle in Euplotes Eurystomus . . . 1 Rainer Storb and Robert L. Amy and Richard K. Wertz and Bernard Fauconnier and Marcel Bessis An Electron Microscope Study of Vitally Stained Single Cells Irradiated with a Ruby Laser Microbeam . . . . . . . . . . 11 Stephen L. Wolfe and Godfrey M. Hewitt The Strandedness of Meiotic Chromosomes from Oncopeltus . . . . . . . . . . . . 31 Allan D. Dingle and Chandler Fulton Development of the Flagellar Apparatus of Naegleria . . . . . . . . . . . . . . 43 Barbara J. Stevens and Hewson Swift RNA Transport from Nucleus to Cytoplasm in Chironomus Salivary Glands . . . . . 55 Lalit M. Srivastava On the Fine Structure of the Cambium of \bionameFraxinus Americana L. . . . . . 79 Joel A. Huberman and Giuseppe Attardi Isolation of Metaphase Chromosomes from HeLa Cells . . . . . . . . . . . . . . . 95 Everett Anderson and William R. Harvey Active Transport by the Cecropia Midgut 107 J. M. Bassot Une Forme Microtubulaire et Paracristalline de Reticulum Endoplasmique dans les Photocytes des Annelides Polynoinæ. (French) [A Microtubular and Paracrystalline Form of Endoplasmic Reticulum in \bionameAnnelides Polynoinæ Photocytes] 135 Jerome S. Kaye and Rachel McMaster-Kaye The Fine Structure and Chemical Composition of Nuclei During Spermiogenesis in the House Cricket . . 159 Gustav Dallner and Robert Nilsson Mechanism of the Cation Effect in Subfractionation of Microsomes . . . . . 181 Judson D. Sheridan Electrophysiological Study of Special Connections Between Cells in the Early Chick Embryo . . . . . . . . . . . . . . ?? Robert L. Trelstad and Jean-Paul Revel and Elizabeth D. Hay Tight Junctions Between Cells in the Early Chick Embryo As Visualized with the Electron Microscope . . . . . . . . ?? Louise M. Luckenbill and Alan S. Cohen The Association of Lipid Droplets with Cytoplasmic Filaments in Avian Subsynovial Adipose Cells . . . . . . . 195 Carl M. Feldherr Nucleocytoplasmic Exchanges During Cell Division . . . . . . . . . . . . . . . . 199 H. P. Rusch and W. Sachsenmaier and Kathryn Behrens and Vera Gruter Synchronization of Mitosis by the Fusion of the Plasmodia of \bionamePhysarum Polycephalum . . . . . . . . . . . . . . 204 Richard M. Hays and Peter Barland The Isolation of the Membrane of the Toad Bladder Epithelial Cell . . . . . . 209
Jose A. Zadunaisky The Location of Sodium in the Transverse Tubules of Skeletal Muscle . . . . . . . ?? Miro Brzin and Virginia M. Tennyson and Philip E. Duffy Acetylcholinesterase in Frog Sympathetic and Dorsal Root Ganglia . . . . . . . . 215 Sten Orrenius and Jan L. E. Ericsson On the Relationship of Liver Glucose-$6$-Phosphatase to the Proliferation of Endoplasmic Reticulum in Phenobarbital Induction . . . . . . . 243 Jack C. Vaughn The Relationship of the `` Sphere Chromatophile `` to the Fate of Displaced Histones Following Histone Transition in Rat Spermiogenesis . . . . 257 Joseph A. Grasso and John W. Woodard The Relationship Between RNA Synthesis and Hemoglobin Synthesis in Amphibian Erythropoiesis . . . . . . . . . . . . . 279 G. D. Shoup and D. M. Prescott and J. R. Wykes Thymidine Triphosphate Synthesis in \bionameTetrahymena . . . . . . . . . . 295 C. T. Ashworth and J. S. Leonard and E. H. Eigenbrodt and F. J. Wrightsman Hepatic Intracellular Osmiophilic Droplets . . . . . . . . . . . . . . . . 301 Robert E. Smith and Marilyn G. Farquhar Lysosome Function in the Regulation of the Secretory Process in Cells of the Anterior Pituitary Gland . . . . . . . . 319 Fritz Miller and Etienne de Harven and George E. Palade The Structure of Eosinophil Leukocyte Granules in Rodents and in Man . . . . . 349 R. E. Coggeshall and E. R. Kandel and I. Kupfermann and R. Waziri A Morphological and Functional Study on a Cluster of Identifiable Neurosecretory Cells in the Abdominal Ganglion of \bionameAplysia Californica . . . . . . 363
H. J. Barr and W. Plaut Comparative Morphology of Nucleolar DNA in \bionameDrosophila . . . . . . . . . ?? Ruth G. Kleinfeld and Jesse E. Sisken Morphological and Kinetic Aspects of Mitotic Arrest by and Recovery from Colcemid . . . . . . . . . . . . . . . . 369 Mahendra P. Jamuar Studies of Spermiogenesis in a Nematode, Nippostrongylus Brasiliensis . . . . . . 381 Asao Hirano and H. M. Zimmerman and Seymour Levine Myelin in the Central Nervous System As Observed in Experimentally Induced Edema in the Rat . . . . . . . . . . . . . . . 397 Ralph A. Jersild A Radioautographic Study of Glyceride Synthesis in Vivo During Intestinal Absorption of Fats and Labeled Glucose 413 J. Cronshaw and L. Hoefert and K. Esau Ultrastructural Features of Beta Leaves Infected with Beet Yellows Virus . . . . 429 Elizabeth C. Raff and J. J. Blum The Effects of Adenosine Triphosphate and Related Compounds on Some Hydrodynamic Properties of Glycerinated Cilia . . . . . . . . . . . . . . . . . 445 Arnold I. Caplan and John W. Greenawalt Biochemical and Ultrastructural Properties of Osmotically Lysed Rat-Liver Mitochondria . . . . . . . . . 455 A. G. Engel and Lois W. Tice Cytochemistry of Phosphatases of the Sarcoplasmic Reticulum . . . . . . . . . 473 Lois W. Tice and A. G. Engel Cytochemistry of Phosphatases of the Sarcoplasmic Reticulum . . . . . . . . . 489 E. Joan Blanchette Ovarian Steroid Cells . . . . . . . . . 501 E. Joan Blanchette Ovarian Steroid Cells . . . . . . . . . 517 Waheeb K. Heneen and Warren W. Nichols Persistence of Nucleoli in Short Term and Long Term Cell Cultures and in Direct Bone Marrow Preparations in Mammalian Materials . . . . . . . . . . 543 J. W. Combs Maturation of Rat Mast Cells . . . . . . 563 J. E. Cummins and H. P. Rusch Limited DNA Synthesis in the Absence of Protein Synthesis in \bionamePhysarum Polycephalum . . . . . . . . . . . . . . 577 Woutera van Iterson and Judith F. M. Hoeniger and Eva Nijman van Zanten Basal Bodies of Bacterial Flagella in Proteus Mirabilis . . . . . . . . . . . 585 Judith F. M. Hoeniger and Woutera van Iterson and Eva Nijman van Zanten Basal Bodies of Bacterial Flagella in Proteus Mirabilis . . . . . . . . . . . 603 Werner W. Franke Isolated Nuclear Membranes . . . . . . . 619 Kiyoshi Hama The Fine Structure of the Schwann Cell Sheath of the Nerve Fiber in the Shrimp (\bionamePenaeus Japonicus) . . . . . . 624 T. B. Mackenzie and G. E. Stone and D. M. Prescott The Durations of G$_1$, S, and G$_2$ at Different Temperatures in \bionameTetrahymena Pyriformis Hsm . . . 633 David M. Phillips Substructure of Flagellar Tubules . . . 635 Joseph G. Gall Microtubule Fine Structure . . . . . . . 639
Woutera van Iterson and Judith F. M. Hoeniger and Eva Nijman van Zanten A ``Microtubule'' in a Bacterium . . . . 1 W. A. Anderson and A. Weissman and R. A. Ellis Cytodifferentiation During Spermiogenesis in Lumbricus Terrestris 11 A. Rambourg and C. P. Leblond Electron Microscope Observations on the Carbohydrate-Rich Cell Coat Present at the Surface of Cells in the Rat . . . . 27 Philip Seeman Transient Holes in the Erythrocyte Membrane During Hypotonic Hemolysis and Stable Holes in the Membrane After Lysis by Saponin and Lysolecithin . . . . . . 55 K. Esau and J. Cronshaw and L. L. Hoefert Relation of Beet Yellows Virus to the Phloem and to Movement in the Sieve Tube 71 George G. Rose The Circumfusion System for Multipurpose Culture Chambers . . . . . . . . . . . . 89 Alan Peters and James E. Vaughn Microtubules and Filaments in the Axons and Astrocytes of Early Postnatal Rat Optic Nerves . . . . . . . . . . . . . . 113 Thomas L. Lentz and J. P. Trinkaus A Fine Structural Study of Cytodifferentiation During Cleavage, Blastula, and Gastrula Stages of Fundulus Heteroclitus . . . . . . . . . 121 J. P. Trinkaus and Thomas L. Lentz Surface Specializations of Fundulus Cells and Their Relation to Cell Movements During Gastrulation . . . . . 139 Russell Ross and Seymour J. Klebanoff Fine Structural Changes in Uterine Smooth Muscle and Fibroblasts in Response to Estrogen . . . . . . . . . . 155 John F. Aronson Polarized Light Observations on Striated Muscle Contraction in a Mite . . . . . . 169 Pierre Baudhuin and Philippe Evrard and Jacques Berthet Electron Microscopic Examination of Subcellular Fractions . . . . . . . . . 181 Sidney Fleischer and Becca Fleischer and Walther Stoeckenius Fine Structure of Lipid-Depleted Mitochondria . . . . . . . . . . . . . . 193 Park S. Nobel and Satoru Murakami Electron Microscopic Evidence for the Location and Amount of Ion Accumulation by Spinach Chloroplasts . . . . . . . . 209 Jesse E. Sisken and Elaina Wilkes and Grace M. Donnelly and Tsuyoshi Kakefuda The Isolation of the Mitotic Apparatus from Mammalian Cells in Culture . . . . 212 B. Bertolini and G. Hassan Acid Phosphatase Associated with the Golgi Apparatus in Human Liver Cells . . 216 Donald Jasper Body Muscles of the Lamprey . . . . . . 219 Frances Kallman and Norman K. Wessells Periodic Repeat Units of Epithelial Cell Tonofilaments . . . . . . . . . . . . . 227 Frances Kallman and Jean Evans and Norman K. Wessells Normal Epidermal Basal Cell Behavior in the Absence of Basement Membrane . . . . 231 Frances Kallman and Jean Evans and Norman K. Wessells Anchor Filament Bundles in Embryonic Feather Germs and Skin . . . . . . . . . 236
Florence Moog and Robert D. Grey Spatial and Temporal Differentiation of Alkaline Phosphatase on the Intestinal Villi of the Mouse . . . . . . . . . . . ?? R. E. Kane The Mitotic Apparatus . . . . . . . . . 243 R. E. Stephens The Mitotic Apparatus . . . . . . . . . 255 Setsuya Fujita Quantitative Analysis of Cell Proliferation and Differentiation in the Cortex of the Postnatal Mouse Cerebellum 277 M. G. Dobb and R. D. B. Fraser and T. P. Macrae The Fine Structure of Silk Fibroin . . . 289 Richard Holmes Preparation from Human Serum of an Alpha-One Protein Which Induces the Immediate Growth of Unadapted Cells in Vitro . . . . . . . . . . . . . . . . . 297 I. Watanabe and S. Okada Effects of Temperature on Growth Rate of Cultured Mammalian Cells (L5178Y) . . . 309 William E. Bowers and John T. Finkenstaedt and Christian de Duve Lysosomes in Lymphoid Tissue . . . . . . 325 William E. Bowers and Christian de Duve Lysosomes in Lymphoid Tissue . . . . . . 339 William E. Bowers and Christian de Duve Lysosomes in Lymphoid Tissue . . . . . . 349 Victor J. Matukas and Bernard J. Panner and J. Lowell Orbison Studies on Ultrastructural Identification and Distribution of Protein-Polysaccharide in Cartilage Matrix . . . . . . . . . . . . . . . . . 365 Miriam M. Salpeter Electron Microscope Radioautography As a Quantitative Tool in Enzyme Cytochemistry . . . . . . . . . . . . . 379 Joseph G. Gall Octagonal Nuclear Pores . . . . . . . . 391 Melvin D. Schoenberg and Richard D. Moore and Austin S. Weisberger Differentiation and Functional Expression of Potential Antibody-Producing Cells in the Presence of Chloramphenicol . . . . . . . . . . . 401 Gian Luigi Sottocasa and Bo Kuylenstierna and Lars Ernster and Anders Bergstrand An Electron-Transport System Associated with the Outer Membrane of Liver Mitochondria . . . . . . . . . . . . . . 415 Mary Bartlett Bunge and Richard P. Bunge and Edith R. Peterson and Margaret R. Murray A Light and Electron Microscope Study of Long-Term Organized Cultures of Rat Dorsal Root Ganglia . . . . . . . . . . 439 Edmund B. Masurovsky and Mary Bartlett Bunge and Richard P. Bunge Cytological Studies of Organotypic Cultures of Rat Dorsal Root Ganglia Following X-Irradiation in Vitro . . . . 467 Edmund B. Masurovsky and Mary Bartlett Bunge and Richard P. Bunge Cytological Studies of Organotypic Cultures of Rat Dorsal Root Ganglia Following X-Irradiation in Vitro . . . . 497 Dan O. McClary and Wilbert D. Bowers Structural Differentiation of Obligately Aerobic and Facultatively Anaerobic Yeasts . . . . . . . . . . . . . . . . . 519 Donald A. Fischman and George Weinbaum The Formation of Multiple Layers of Membrane-Like Structures in \bionameEscherichia coli B . . . . . . . 524 Phillip Zeidenberg and Sten Orrenius and Lars Ernster Increase in Levels of Glucuronylating Enzymes and Associated Rise in Activities of Mitochondrial Oxidative Enzymes Upon Phenobarbital Administration in the Rat . . . . . . . 528 T. M. Rizki Ultrastructure of the Secretory Inclusions of the Salivary Gland Cell in \bionameDrosophila . . . . . . . . . . . 531
Jerome Vanderberg and Johannes Rhodin Differentiation of Nuclear and Cytoplasmic Fine Structure During Sporogonic Development of Plasmodium Berghei . . . . . . . . . . . . . . . . ?? Martin Hagopian and David Spiro The Sarcoplasmic Reticulum and Its Association with the T System in an Insect . . . . . . . . . . . . . . . . . 535 Philippe Chevaillier Mise En Evidence Et Etude Cytochimique D'Une Proteine Basique Extranucleaire Dans Les Spermatozoides Des Crustaces Decapodes . . . . . . . . . . . . . . . 547 Donald A. Fischman An Electron Microscope Study of Myofibril Formation in Embryonic Chick Skeletal Muscle . . . . . . . . . . . . 557 Miro Brzin and Wolf-D. Dettbarn Cholinesterase Activity of Nodal and Internodal Regions of Myelinated Nerve Fibers of Frog . . . . . . . . . . . . . 577 N. A. Barnicot A Study of Newt Mitotic Chromosomes by Negative Staining . . . . . . . . . . . 585 Gonzague S. Kistler and Peter R. B. Caldwell and Ewald R. Weibel Development of Fine Structural Damage to Alveolar and Capillary Lining Cells in Oxygen-Poisoned Rat Lungs . . . . . . . 605 R. C. Graham and M. J. Karnovsky and A. W. Shafer and E. A. Glass and Manfred L. Karnovsky Metabolic and Morphological Observations on the Effect of Surface-Active Agents on Leukocytes . . . . . . . . . . . . . 629 Takahiko Kato and Masanori Kurokawa Isolation of Cell Nuclei from the Mammalian Cerebral Cortex and Their Assortment on a Morphological Basis . . 649 Jane Rearick Shoup Spermiogenesis in Wild Type and in a Male Sterility Mutant of \bionameDrosophila Melanogaster . . . . 663 Lawrence Einar Scheving and John Edward Pauly Circadian Phase Relationships of Thymidine-$^3$H Uptake, Labeled Nuclei, Grain Counts, and Cell Division Rate in Rat Corneal Epithelium . . . . . . . . . 677 M. M. Cassidy and C. S. Tidball Cellular Mechanism of Intestinal Permeability Alterations Produced by Chelation Depletion . . . . . . . . . . 685 John L. Mego and Francisco Bertini and J. Donald McQueen The Use of Formaldehyde-Treated$^{131}$ I-Albumin in the Study of Digestive Vacuoles and Some Properties of These Particles from Mouse Liver . . . . . . . 699 John A. Hardin and Gerald E. Einem and David T. Lindsay Simultaneous Synthesis of Histone and DNA in Synchronously Dividing \bionameTetrahymena Pyriformis . . . . . 709 Carl Schnaitman and V. Gene Erwin and John W. Greenawalt The Submitochondrial Localization of Monoamine Oxidase . . . . . . . . . . . 719 Hugues J.-P. Ryser Studies on Protein Uptake by Isolated Tumor Cells . . . . . . . . . . . . . . 737 Ronald A. Bergman Motor Nerve Endings of Twitch Muscle Fibers in Hippocampus Hudsonius . . . . 751 Thomas E. Morgan and Gary L. Huber Loss of Lipid During Fixation for Electron Microscopy . . . . . . . . . . 757 J. D. Berlin The Localization of Acid Mucopolysaccharides in the Golgi Complex of Intestinal Goblet Cells . . . . . . . 760 C. C. Widnell and T. H. Hamilton and J. R. Tata The Isolation of Enzymically Active Nuclei from the Rat Heart and Uterus . . 766 Arne Jepsen and Jòrgen Theilade Electron Microscopic Identification of Epithelial Cells in Tissue Culture of Oral Mucous Membrane . . . . . . . . . . 770
D. A. Cameron and H. A. Paschall and R. A. Robinson Changes in the Fine Structure of Bone Cells After the Administration of Parathyroid Extract . . . . . . . . . . 1 Huai-San Lin A Peculiar Configuration of Agranular Reticulum (Canaliculate Lamellar Body) in the Rat Pinealocyte . . . . . . . . . 15 F. Fernández-Madrid Biosynthesis of Collagen . . . . . . . . 27 Zane B. Carothers and Gerald L. Kreitner Studies of Spermatogenesis in the Hepaticae . . . . . . . . . . . . . . . 43 Theodore Peters and Charles A. Ashley An Artefact in Radioautography Due to Binding of Free Amino Acids to Tissues by Fixatives . . . . . . . . . . . . . . 53 Richard W. Young The Renewal of Photoreceptor Cell Outer Segments . . . . . . . . . . . . . . . . 61 David M. Phillips Giant Centriole Formation in Sciara . . 73 Peter M. Robinson and Christopher Bell The Localization of Acetylcholinesterase at the Autonomic Neuromuscular Junction 93 Edward A. Johnson and Joachim R. Sommer A Strand of Cardiac Muscle . . . . . . . 103 Ernest M. Gifford and Kenneth D. Stewart Ultrastructure of the Shoot Apex of Chenopodium Album and Certain Other Seed Plants . . . . . . . . . . . . . . . . . 131 Eldon H. Newcomb Fine Structure of Protein-Storing Plastids in Bean Root Tips . . . . . . . 143 H. Clarke Anderson and P. R. Coulter Bone Formation Induced in Mouse Thigh by Cultured Human Cells . . . . . . . . . . 165 Allan L. Allenspach and L. E. Roth Structural Variations During Mitosis in the Chick Embryo . . . . . . . . . . . . 179 Paul M. Kraemer Configuration Change of Surface Sialic Acid During Mitosis . . . . . . . . . . 197 M. J. Griffin and R. P. Cox and N. Grujic A Chemical Method for the Isolation of HeLa Cell Nuclei and the Nuclear Localization of HeLa Cell Alkaline Phosphatase . . . . . . . . . . . . . . 200 Toshihiko Matsusaka Atpase Activity in the Ciliary Rootlet of Human Retinal Rods . . . . . . . . . 203 J. Leslie Glick and Anthony P. Salim DNA-Induced Pigment Production in a Hamster Cell Line . . . . . . . . . . . 209 J. Hugon and M. Borgers Fine Structural Localization of Lysosomal Enzymes in the Absorbing Cells of the Duodenal Mucosa of the Mouse . . 212 George C. Carroll The Ultrastructure of Ascospore Delimitation in Saccobolus Kerverni . . 218
N. Nanninga Fine Structure Observed in 50S Ribosomal Subunits of Bacillus Subtilis . . . . . ?? Werner R. Loewenstein and Yoshinobu Kanno Intercellular Communication and Tissue Growth . . . . . . . . . . . . . . . . . 225 Werner R. Loewenstein and Richard D. Penn Intercellular Communication and Tissue Growth . . . . . . . . . . . . . . . . . 235 Paul G. Bartels and T. Elliot Weier Particle Arrangements in Proplastids of Triticum Vulgare L. Seedlings . . . . . 243 Philip W. Brandt and Enrique Lopez and John P. Reuben and Harry Grundfest The Relationship Between Myofilament Packing Density and Sarcomere Length in Frog Striated Muscle . . . . . . . . . . 255 Donald W. King and M. L. Barnhisel Synthesis of RNA in Mammalian Cells During Mitosis and Interphase . . . . . 265 Jane L. Showacre and W. G. Cooper and D. M. Prescott Nucleolar and Nuclear RNA Synthesis During the Cell Life Cycle in Monkey and Pig Kidney Cells in Vitro . . . . . . . 273 M. V. Narasimha Rao and David M. Prescott Micronuclear RNA Synthesis in Paramecium Caudatum . . . . . . . . . . . . . . . . 281 Eva Eliasson and G. Eric Bauer and Tore Hultin Reversible Degradation of Polyribosomes in Chang Cells Cultured in a Glutamine-Deficient Medium . . . . . . . 287 L. Bachmann and M. M. Salpeter Absolute Sensitivity of Electron Microscope Radioautography . . . . . . . 299 Paul K. Nakane and G. Barry Pierce Enzyme-Labeled Antibodies for the Light and Electron Microscopic Localization of Tissue Antigens . . . . . . . . . . . . 307 Olga Stein and Yechezkiel Stein Lipid Synthesis, Intracellular Transport, Storage, and Secretion . . . 319 Leonard Weiss Studies on Cell Deformability . . . . . 341 Norman S. Cohn and P. van Duijn Constancy of DNA Content in Adrenal Medulla Nuclei of Cold-Treated Rats . . 349 Ji\vri Lom and Eugene N. Kozloff The Ultrastructure of Phalacrocleptes Verruciformis, an Unciliated Ciliate Parasitizing the Polychaete Schizobranchia Insignis . . . . . . . . 355 Arnaldo Lasansky Cell Junctions in Ommatidia of Limulus 365 Elvin Harper and Sam Seifter and Berta Scharrer Electron Microscopic and Biochemical Characterization of Collagen in Blattarian Insects . . . . . . . . . . . 385 David W. Deamer and Antony Crofts Action of Triton X-100 on Chloroplast Membranes . . . . . . . . . . . . . . . 395 Rolf H. Dahl and James N. Pratley The Effects of Magnesium on Nucleoside Phosphatase Activity in Frog Skin . . . 411 Eric Holtzman and Alex B. Novikoff and Humberto Villaverde Lysosomes and Gerl in Normal and Chromatolytic Neurons of the Rat Ganglion Nodosum . . . . . . . . . . . . 419 Russell L. Deter and Christian de Duve Influence of Glucagon, an Inducer of Cellular Autophagy, on Some Physical Properties of Rat Liver Lysosomes . . . 437
J. P. Revel and M. J. Karnovsky Hexagonal Array of Subunits in Intercellular Junctions of the Mouse Heart and Liver . . . . . . . . . . . . ?? David P. Bloch and Robert A. MacQuigg and Sheilah D. Brack and Jung-Rung Wu The Syntheses of Deoxyribonucleic Acid and Histone in the Onion Root Meristem 451 E. G. Cleary and L. B. Sandberg and D. S. Jackson The Changes in Chemical Composition During Development of the Bovine Nuchal Ligament . . . . . . . . . . . . . . . . 469 Z. T. Wirtschafter and E. G. Cleary and D. S. Jackson and L. B. Sandberg Histological Changes During the Development of the Bovine Nuchal Ligament . . . . . . . . . . . . . . . . 481 J. C. H. de Man and N. J. A. Noorduyn Light and Electron Microscopic Radioautography of Hepatic Cell Nucleoli in Mice Treated with Actinomycin D . . . 489 Lawrence K. Schneider and William O. Rieke DNA Replication Patterns and Chromosomal Protein Synthesis in Opossum Lymphocytes in Vitro . . . . . . . . . . . . . . . . 497 T. Bisalputra and A. A. Bisalputra Chloroplast and Mitochondrial DNA in a Brown Alga Egregia Menziesii . . . . . . 511 Lowell E. Hokin and Dorothy Huebner Radioautographic Localization of the Increased Synthesis of Phosphatidylinositol in Response to Pancreozymin Or Acetylcholine in Guinea Pig Pancreas Slices . . . . . . . . . . 521 J. F. Reger and D. P. Cooper A Comparative Study on the Fine Structure of the Basalar Muscle of the Wing and the Tibial Extensor Muscle of the Leg of the Lepidopteran Achalarus Lyciades . . . . . . . . . . . . . . . . 531 David L. Ringo Flagellar Motion and Fine Structure of the Flagellar Apparatus in Chlamydomonas 543 M. R. Bennett and D. C. Rogers A Study of the Innervation of the \bionameTaenia Coli . . . . . . . . . . 573 James W. MacInnes and Robert B. Uretz Thermal Depolarization of Fluorescence from Polytene Chromosomes Stained with Acridine Orange . . . . . . . . . . . . 597 Teruo Suzuki and F. K. Mostofi Intramitochondrial Filamentous Bodies in the Thick Limb of Henle of the Rat Kidney . . . . . . . . . . . . . . . . . 605 Ehud Skutelsky and David Danon An Electron Microscopic Study of Nuclear Elimination from the Late Erythroblast 625 Lester Goldstein and David M. Prescott Proteins in Nucleocytoplasmic Interactions . . . . . . . . . . . . . . 637 Joseph A. Grasso and John W. Woodard DNA Synthesis and Mitosis in Erythropoietic Cells . . . . . . . . . . 645 Alexandra von der Decken Evidence for Regulation of Protein Synthesis at the Translation Level in Response to Dietary Alterations . . . . 657 Katherine Esau and James Cronshaw Relation of Tobacco Mosaic Virus to the Host Cells . . . . . . . . . . . . . . . 665 Tsuranobu Shirahama and Alan S. Cohen High-Resolution Electron Microscopic Analysis of the Amyloid Fibril . . . . . 679 Francis J. Carey and Olive S. Pettengill A Time-Lapse Study of Effects of Anticellular Antibody on Membrane Mobility and Phagocytic Activity of HeLa Cells . . . . . . . . . . . . . . . . . 709 Andrew Bajer Notes on Ultrastructure and Some Properties of Transport Within the Living Mitotic Spindle . . . . . . . . . 713 M. Kumegawa and M. Cattoni and George G. Rose An Unusual Droplet in Submandibular Gland of New Born Mice . . . . . . . . . 720 Martin A. Gorovsky and John Woodard Histone Content of Chromosomal Loci Active and Inactive in RNA Synthesis . . 723 David E. Schlegel and Gustaaf A. de Zoeten Improved Resolution in Light Microscope Radioautography . . . . . . . . . . . . 728
G. D. Clark-Walker and Anthony W. Linnane The Biogenesis of Mitochondria in \bionameSaccharomyces Cerevisiae . . . . 1 Jack Rosenbluth Obliquely Striated Muscle . . . . . . . 15 Hatao Kato and Avery A. Sandberg Chromosome Pulverization in Human Binucleate Cells Following Colcemid Treatment . . . . . . . . . . . . . . . 35 L. E. Roth Electron Microscopy of Mitosis in Amebae 47 R. Simard and W. Bernhard A Heat-Sensitive Cellular Function Located in the Nucleolus . . . . . . . . 61 Marion Himes DNA-Protein Binding in Interphase Chromosomes . . . . . . . . . . . . . . 77 Irwin A. Schafer and Lloyd Silverman and Julia C. Sullivan and William Van B. Robertson Ascorbic Acid Deficiency in Cultured Human Fibroblasts . . . . . . . . . . . 83 Jesse E. Sisken and Elaina Wilkes The Time of Synthesis and the Conservation of Mitosis-Related Proteins in Cultured Human Amnion Cells . . . . . 97 Norman E. Kemp and Nancy L. Istock Cortical Changes in Growing Oocytes and in Fertilized Or Pricked Eggs of Rana Pipiens . . . . . . . . . . . . . . . . 111 Robert R. Cardell and Susan Badenhausen and Keith R. Porter Intestinal Triglyceride Absorption in the Rat . . . . . . . . . . . . . . . . 123 Richard Davis and George B. Koelle Electron Microscopic Localization of Acetylcholinesterase and Nonspecific Cholinesterase at the Neuromuscular Junction by the Gold-Thiocholine and Gold-Thiolacetic Acid Methods . . . . . 157 Roland J. Lesseps The Removal by Phospholipase C of a Layer of Lanthanum-Staining Material External to the Cell Membrane in Embryonic Chick Cells . . . . . . . . . 173 Elliot Bindler and Frank S. Labella and Madhu Sanwal Isolated Nerve Endings (Neurosecretosomes) from the Posterior Pituitary . . . . . . . . . . . . . . . 185 T. S. Reese and Morris J. Karnovsky Fine Structural Localization of a Blood-Brain Barrier to Exogenous Peroxidase . . . . . . . . . . . . . . . 207 Edward D. Korn and Robert A. Weisman Phagocytosis of Latex Beads by \bionameAcanthamoeba . . . . . . . . . . 219 Masamichi Aikawa and Clay G. Huff and Helmuth Sprinz Fine Structure of the Asexual Stages of Plasmodium Elongatum . . . . . . . . . . 229 Olga Stein and Yechezkiel Stein Lipid Synthesis, Intracellular Transport, and Secretion . . . . . . . . 251 Edward Koenig Observations on Selected Isolated Retinal Elements and an Analysis of Rod Cell RNA of the Rabbit . . . . . . . . . 265 Robert K. Schenk and David Spiro and Joseph Wiener Cartilage Resorption in the Tibial Epiphyseal Plate of Growing Rats . . . . 275 O. Lindberg and J. De Pierre and E. Rylander and B. A. Afzelius Studies of the Mitochondrial Energy-Transfer System of Brown Adipose Tissue . . . . . . . . . . . . . . . . . 293 John A. Terzakis and Helmuth Sprinz and Ronald A. Ward The Transformation of the Plasmodium Gallinaceum Oocyst in Aedes Aegypti Mosquitoes . . . . . . . . . . . . . . . 311 Lewis G. Tilney and Keith R. Porter Studies on the Microtubules in Heliozoa 327 Joel L. Rosenbaum and F. M. Child Flagellar Regeneration in Protozoan Flagellates . . . . . . . . . . . . . . 345 Walther Stoeckenius and Robert Rowen A Morphological Study of Halobacterium Halobium and Its Lysis in Media of Low Salt Concentration . . . . . . . . . . . 365 D. E. Slagel and J.-E. Edström A Rapid Method for Calculation of the Total Amount of Absorbing Substance in Microextracts . . . . . . . . . . . . . 395 Sidney Goldfischer The Cytochemical Localization of Myoglobin in Striated Muscle of Man and Walrus . . . . . . . . . . . . . . . . . 398 Alan D. Sudweeks and Rolla B. Hill Control of Liver Cell Replication by Albumin Need . . . . . . . . . . . . . . 404
C. F. Doggenweiler and John E. Heuser Ultrastructure of the Prawn Nerve Sheaths . . . . . . . . . . . . . . . . 407 Raúl Hinojosa and J. David Robertson Ultrastructure of the Spoon Type Synaptic Endings in the Nucleus Vestibularis Tangentialis of the Chick 421 Marvin H. Stromer and D. E. Goll and L. E. Roth Morphology of Rigor-Shortened Bovine Muscle and the Effect of Trypsin on Pre- and Postrigor Myofibrils . . . . . . . . 431 T. M. Mukherjee and A. Wynn Williams A Comparative Study of the Ultrastructure of Microvilli in the Epithelium of Small and Large Intestine of Mice . . . . . . . . . . . . . . . . 447 R. A. Jenkins Fine Structure of Division in Ciliate Protozoa . . . . . . . . . . . . . . . . 463 Arthur M. Zimmerman and Selma Zimmerman Action of Colcemid in Sea Urchin Eggs 483 M. Steinert and Suzanne van Assel The Loss of Kinetoplastic DNA in Two Species of Trypanosomatidae Treated with Acriflavine . . . . . . . . . . . . . . 489 Leon Marcus and H. Ris and H. O. Halvorson and R. K. Bretthauer and R. M. Bock Occurrence, Isolation, and Characterization of Polyribosomes in Yeast . . . . . . . . . . . . . . . . . 505 Helen A. Mintz and David H. Yawn and Brian Safer and Edward Bresnick and Annabel G. Liebelt and Zack R. Blailock and Erwin R. Rabin and Arnold Schwartz Morphological and Biochemical Studies of Isolated Mitochondria from Fetal, Neonatal, and Adult Liver and from Neoplastic Tissues . . . . . . . . . . . 513 G. G. Borisy and E. W. Taylor The Mechanism of Action of Colchicine 525 G. G. Borisy and E. W. Taylor The Mechanism of Action of Colchicine 535 M. L. Shelanski and E. W. Taylor Isolation of a Protein Subunit from Microtubules . . . . . . . . . . . . . . 549 Asao Hirano and Herbert M. Dembitzer A Structural Analysis of the Myelin Sheath in the Central Nervous System . . 555 Harold W. Fisher and T. W. Cooper Electron Microscope Studies of the Microvilli of HeLa Cells . . . . . . . . 569 James D. Jamieson and George E. Palade Intracellular Transport of Secretory Proteins in the Pancreatic Exocrine Cell 577 James D. Jamieson and George E. Palade Intracellular Transport of Secretory Proteins in the Pancreatic Exocrine Cell 597 Arnaldo Lasansky The Pathway Between Hyaloid Blood and Retinal Neurons in the Toad . . . . . . 617 Edward D. Korn A Chromatographic and Spectrophotometric Study of the Products of the Reaction of Osmium Tetroxide with Unsaturated Lipids 627 Howard J. Arnott and Kenneth M. Smith Intracellular Inclusions in the Gut Epithelial Cells of Piesma Cinereum Say 639 Arthur T. Hertig and Eleanor C. Adams Studies on the Human Oocyte and Its Follicle . . . . . . . . . . . . . . . . 647 Takashi Tokumitsu and Karl Maramorosch Cytoplasmic Protrusions in Insect Cells During Mitosis in Vitro . . . . . . . . 677 Elliott Robbins and Matthew D. Scharff The Absence of a Detectable G$_1$ Phase in a Cultured Strain of Chinese Hamster Lung Cell . . . . . . . . . . . . . . . 684 F. R. Susi and W. D. Belt and J. W. Kelly Fine Structure of Fibrillar Complexes Associated with the Basement Membrane in Human Oral Mucosa . . . . . . . . . . . 686 J. Metuzals Helical Arrangement of the Subunits of the Neurofibrillar Bundles Isolated from Leech Nervous System . . . . . . . . . . 690 O. Behnke Incomplete Microtubules Observed in Mammalian Blood Platelets During Microtubule Polymerization . . . . . . . 697 J. Berthet and P. Baudhuin A Remark About the Determination of the Water Content of Mitochondria . . . . . 701
C. Barros and J. M. Bedford and L. E. Franklin and C. R. Austin Membrane Vesiculation As a Feature of the Mammalian Acrosome Reaction . . . . ?? Nancy L. Trotter Electron-Opaque Bodies and Fat Droplets in Mouse Liver After Fasting Or Glucose Injection . . . . . . . . . . . . . . . 703 Bernard P. Lane Localization of Products of ATP Hydrolysis in Mammalian Smooth Muscle Cells . . . . . . . . . . . . . . . . . 713 R. Gerald Suskind Effect of Temperature of Aldehyde Fixation on the Radioautographic Localization of Ribonucleoprotein in Nucleoli of HeLa Cells . . . . . . . . . 721 A. K. Asbury Schwann Cell Proliferation in Developing Mouse Sciatic Nerve . . . . . . . . . . 735 Philip M. Seeman and George E. Palade Acid Phosphatase Localization in Rabbit Eosinophils . . . . . . . . . . . . . . 745 W. Bernhard and Elizabeth H. Leduc Ultrathin Frozen Sections . . . . . . . 757 Elizabeth H. Leduc and W. Bernhard and S. J. Holt and J. P. Tranzer Ultrathin Frozen Sections . . . . . . . 773 Arnold M. Seligman and Robert E. Plapinger and Hannah L. Wasserkrug and Chandicharan Deb and Jacob S. Hanker Ultrastructural Demonstration of Cytochrome Oxidase Activity by the Nadi Reaction with Osmiophilic Reagents . . . 787 James Cronshaw and Katherine Esau Tubular and Fibrillar Components of Mature and Differentiating Sieve Elements . . . . . . . . . . . . . . . . 801 Leonard Napolitano and Francis Lebaron and Joseph Scaletti Preservation of Myelin Lamellar Structure in the Absence of Lipid . . . 817 Douglas E. Kelly Models of Muscle Z-Band Fine Structure Based on a Looping Filament Configuration . . . . . . . . . . . . . 827 J. Frankel Studies on the Maintenance of Oral Development in \bionameTetrahymena Pyriformis Gl-C . . . . . . . . . . . . 841 Lionel I. Rebhun and Greta Sander Ultrastructure and Birefringence of the Isolated Mitotic Apparatus of Marine Eggs . . . . . . . . . . . . . . . . . . 859 Baccio Baccetti Collagen of the Earthworms . . . . . . . 885 N. Tulchin and G. M. Mateyko and M. J. Kopac Drosophila Salivary Glands in Vitro . . 891 M. Kumegawa and M. Cattoni and G. G. Rose Electron Microscopy of Oral Cells in Vitro . . . . . . . . . . . . . . . . . 897 J. R. Sommer and W. Hasselbach The Effect of Glutaraldehyde and Formaldehyde on the Calcium Pump of the Sarcoplasmic Reticulum . . . . . . . . . 902 Carl W. Schaefer and Jerome P. Vanderberg and Johannes Rhodin The Fine Structure of Mosquito Midgut Muscle . . . . . . . . . . . . . . . . . 905 Michael R. Levy and Ann E. Hunt L-$ \alpha $-hydroxy acid oxidase activity in \bionameTetrahymena . . . . 911 S. Okada A Simple Graphic Method of Computing the Parameters of the Life Cycle of Cultured Mammalian Cells in the Exponential Growth Phase . . . . . . . . . . . . . . 915 Akio Yamauchi and Geoffrey Burnstock Nerve-Myoepithelium and Nerve-Glandular Epithelium Contacts in the Lacrimal Gland of the Sheep . . . . . . . . . . . 917
Jack L. Pate and Erling J. Ordal The Fine Structure of Chondrococcus Columnaris . . . . . . . . . . . . . . . 1 Jack L. Pate and John L. Johnson and Erling J. Ordal The Fine Structure of Chondrococcus Columnaris . . . . . . . . . . . . . . . 15 Jack L. Pate and Erling J. Ordal The Fine Structure of Chondrococcus Columnaris . . . . . . . . . . . . . . . 37 R. A. Tobey and E. C. Anderson and D. F. Petersen The Effect of Thymidine on the Duration of G$_1$ in Chinese Hamster Cells . . . 53 Lloyd Silverman and Laurence H. Frommhagen and David Glick Measurement of Influenza Virus-Antibody Reaction by Quantitative Electron Microscopy . . . . . . . . . . . . . . . 61 Wolf H. Fahrenbach The Fine Structure of Fast and Slow Crustacean Muscles . . . . . . . . . . . 69 H. Clarke Anderson Electron Microscopic Studies of Induced Cartilage Development and Calcification 81 Masamichi Aikawa Ultrastructure of the Pellicular Complex of Plasmodium Fallax . . . . . . . . . . 103 Bronnetta L. Scott Thymidine-$^3$H Electron Microscope Radioautography of Osteogenic Cells in the Fetal Rat . . . . . . . . . . . . . 115 Donald Svoboda and Harold Grady and Daniel Azarnoff Microbodies in Experimentally Altered Cells . . . . . . . . . . . . . . . . . 127 J. Richard McIntosh and Keith R. Porter Microtubules in the Spermatids of the Domestic Fowl . . . . . . . . . . . . . 153 Marion Himes An Analysis of Heterochromatin in Maize Root Tips . . . . . . . . . . . . . . . 175 M. Weintraub and H. W. Ragetli and V. T. John Some Conditions Affecting the Intracellular Arrangement and Concentration of Tobacco Mosaic Virus Particles in Local Lesions . . . . . . . 183 Everett Anderson The Formation of the Primary Envelope During Oocyte Differentiation in Teleosts . . . . . . . . . . . . . . . . 193 Morris J. Karnovsky The Ultrastructural Basis of Capillary Permeability Studied with Peroxidase As a Tracer . . . . . . . . . . . . . . . . 213 Charles F. Simpson and J. M. Kling The Mechanism of Denucleation in Circulating Erythroblasts . . . . . . . 237 Thomas F. Roth and Michio Ito DNA-Dependent Formation of the Synaptinemal Complex at Meiotic Prophase 247 George Hug and William K. Schubert Lysosomes in Type Ii Glycogenosis . . . ?? Sandra Winicur Reactivation of Ethanol-Calcium-Isolated Cilia from \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . ?? W. W. Nichols and P. Aula and A. Levan and W. Heneen and E. Norrby Radioautography with Tritiated Thymidine in Measles and Sendai Virus-Induced Chromosome Pulverizations . . . . . . . 257 I. Pastan and S. H. Wollman Colloid Droplet Formation in Dog Thyroid in Vitro . . . . . . . . . . . . . . . . 262 Gunnar D. Bloom A Nucleus with Cytoplasmic Features . . 266 Thomas Maack Changes in the Activity of Acid Hydrolases During Renal Reabsorption of Lysozyme . . . . . . . . . . . . . . . . 268 John A. Terzakis Substructure in an Epithelial Basal Lamina (Basement Membrane) . . . . . . . 273 B. R. Brinkley and Patricia Murphy and L. Carole Richardson Procedure for Embedding in Situ Selected Cells Cultured in Vitro . . . . . . . . 279
Russell L. Deter and Pierre Baudhuin and Christian de Duve Participation of Lysosomes in Cellular Autophagy Induced in Rat Liver by Glucagon . . . . . . . . . . . . . . . . ?? Eldon H. Newcomb A Spiny Vesicle in Slime-Producing Cells of the Bean Root . . . . . . . . . . . . ?? I. Watanabe and S. Okada Stationary Phase of Cultured Mammalian Cells (L5178Y) . . . . . . . . . . . . . 285 P. R. Mahadevan and E. L. Tatum Localization of Structural Polymers in the Cell Wall of Neurospora Crassa . . . 295 Bernard J. Panner and Carl R. Honig Filament Ultrastructure and Organization in Vertebrate Smooth Muscle . . . . . . 303 Darryll E. Outka and Byron C. Kluss The Ameba-To-Flagellate Transformation in Tetramitus Rostratus . . . . . . . . 323 Leonard Weiss Studies of Cell Deformability . . . . . 347 Daniel S. Friend and Marilyn G. Farquhar Functions of Coated Vesicles During Protein Absorption in the Rat Vas Deferens . . . . . . . . . . . . . . . . 357 Eugene Y. F. Shen Microspectrophotometric Analysis of Nuclear DNA in Chara Zeylanica . . . . . 377 Vincent T. Marchesi and George E. Palade The localization of Mg--Na--K-activated adenosine triphosphatase on red cell ghost membranes . . . . . . . . . . . . 385 Elizabeth B. Ezerman and Harunori Ishikawa Differentiation of the Sarcoplasmic Reticulum and T System in Developing Chick Skeletal Muscle in Vitro . . . . . 405 Nancy J. Lane Spheroidal and Ring Nucleoli in Amphibian Oocytes . . . . . . . . . . . 421 Scott E. Dietert The Columnar Cells Occurring in the Parietal Layer of Bowman's Capsule . . . 435 Y. Shimada and D. A. Fischman and A. A. Moscona The Fine Structure of Embryonic Chick Skeletal Muscle Cells Differentiated in Vitro . . . . . . . . . . . . . . . . . 445 Nirmal K. Das and Julie Micou-Eastwood and Max Alfert Cytochemical and Biochemical Properties of Basic Proteins of Urechis Acrosomes 455 Tsuranobu Shirahama and Alan S. Cohen Reconstitution of Amyloid Fibrils from Alkaline Extracts . . . . . . . . . . . 459 Bernhard Kramarsky and Richard Siegler and Marvin A. Rich Presence of Endothelial Fenestrations in Thymic Capillaries of Mice . . . . . . . 464 Klaus Wolff The Fine Structure of the Langerhans Cell Granule . . . . . . . . . . . . . . 468 Paul F. Parakkal Transfer of Premelanosomes into the Keratinizing Cells of Albino Hair Follicle . . . . . . . . . . . . . . . . 473 B. G. T. Pogo and V. G. Allfrey and A. E. Mirsky The Effect of Phytohemagglutinin on Ribonucleic Acid Synthesis and Histone Acetylation in Equine Leukocytes . . . . 477 Jean H. Priest and Judith E. Heady and Robert E. Priest Delayed Onset of Replication of Human X Chromosomes . . . . . . . . . . . . . . 483
Marvin H. Stromer and D. J. Hartshorne and R. V. Rice Removal and Reconstitution of Z-Line Material in a Striated Muscle . . . . . ?? Emerson S. Hawley and R. P. Wagner Synchronous Mitochondrial Division in Neurospora Crassa . . . . . . . . . . . 489 A. Tixier-Vidal and R. Picart Etude Quantitative Par Radioautographie Au Microscope Electronique De L'Utilisation De La Dl-Leucine-$^3$ H Par Les Cellules De L'Hypophyse Du Canard En Culture Organotypiqe . . . . . 501 I. Ohad and P. Siekevitz and G. E. Palade Biogenesis of Chloroplast Membranes . . 521 I. Ohad and P. Siekevitz and G. E. Palade Biogenesis of Chloroplast Membranes . . 553 Charles E. Stirling and William B. Kinter High-Resolution Radioautography of Galactose-$^3$H Accumulation in Rings of Hamster Intestine . . . . . . . . . . . 585 Charles E. Stirling High-Resolution Radioautography of Phlorizin-$^3$H in Rings of Hamster Intestine . . . . . . . . . . . . . . . 605 Maurice M. Black and Hudson R. Ansley Antigen-Induced Changes in Lymphoid Cell Histones . . . . . . . . . . . . . . . . 619 Maurice M. Black and Hudson R. Ansley Antigen-Induced Changes in Lymphoid Cell Histones . . . . . . . . . . . . . . . . 627 Pierre Baudhuin and Jacques Berthet Electron Microscopic Examination of Subcellular Fractions . . . . . . . . . 631 Robert S. Verbin and Emmanuel Farber Effect of Cycloheximide on the Cell Cycle of the Crypts of the Small Intestine of the Rat . . . . . . . . . . 649 Peter M. Ray Radioautographic Study of Cell Wall Deposition in Growing Plant Cells . . . 659 Roger B. Howard and A. Kent Christensen and Frederic A. Gibbs and Leroy A. Pesch The Enzymatic Preparation of Isolated Intact Parenchymal Cells from Rat Liver 675 H. Ginsburg and D. Lagunoff The in Vitro Differentiation of Mast Cells . . . . . . . . . . . . . . . . . 685 David E. Comings Histones of Genetically Active and Inactive Chromatin . . . . . . . . . . . 699 Bonnie Sue Ebstein Tritiated Actinomycin D As a Cytochemical Label for Small Amounts of DNA . . . . . . . . . . . . . . . . . . 709 E. Plessmann Camargo and W. Plaut The Radioautographic Detection of DNA with Tritiated Actinomycin D . . . . . . 713 René Simard The Binding of Actinomycin D-$^3$H to Heterochromatin As Studied by Quantitative High Resolution Radioautography . . . . . . . . . . . . 716 Stuart Hodson and J. Marshall Tyrosine Incorporation into the Rabbit Retina . . . . . . . . . . . . . . . . . 722 Harvard Lyman Specific Inhibition of Chloroplast Replication in Euglena Gracilis by Nalidixic Acid . . . . . . . . . . . . . 726 M. A. Williams More Intramitochondrial Bodies . . . . . 730
Arthur L. Frank and A. Kent Christensen Localization of Acid Phosphatase in Lipofuscin Granules and Possible Autophagic Vacuoles in Interstitial Cells of the Guinea Pig Testis . . . . . 1 Arnold I. Caplan and John W. Greenawalt The Effects of Osmotic Lysis on the Oxidative Phosphorylation and Compartmentation of Rat Liver Mitochondria . . . . . . . . . . . . . . 15 J. Gomez-Acebo and R. Parrilla and J. L. R-Candela Fine Structure of the A and D Cells of the Rabbit Endocrine Pancreas in Vivo and Incubated in Vitro . . . . . . . . . 33 Richard S. Morgan and Henry S. Slayter and David L. Weller Isolation of Ribosomes from Cysts of Entamoeba Invadens . . . . . . . . . . . 45 Lester Goldstein and David M. Prescott Proteins in Nucleocytoplasmic Interactions . . . . . . . . . . . . . . 53 Olga Stein and Yechezkiel Stein Lipid Synthesis, Intracellular Transport, and Storage . . . . . . . . . 63 F. L. Renaud and A. J. Rowe and I. R. Gibbons Some Properties of the Protein Forming the Outer Fibers of Cilia . . . . . . . 79 R. Soeiro and M. H. Vaughan and J. E. Darnell The Effect of Puromycin on Intranuclear Steps in Ribosome Biosynthesis . . . . . 91 Charles F. Simpson and J. M. Kling The Mechanism of Mitochondrial Extrusion from Phenylhydrazine-Induced Reticulocytes in the Circulating Blood 103 Richard Bischoff and Howard Holtzer The Effect of Mitotic Inhibitors on Myogenesis in Vitro . . . . . . . . . . 111 L. V. Leak and J. F. Burke Ultrastructural Studies on the Lymphatic Anchoring Filaments . . . . . . . . . . 129 Constantino Sotelo and Sanford L. Palay The Fine Structure of the Lateral Vestibular Nucleus in the Rat . . . . . 151 A. I. Kahri Effects of Actinomycin D and Puromycin on the Acth-Induced Ultrastructural Transformation of Mitochondria of Cortical Cells of Rat Adrenals in Tissue Culture . . . . . . . . . . . . . . . . 181 Samuel C. Silverstein and Samuel Dales The Penetration of Reovirus RNA and Initiation of Its Genetic Function in L-Strain Fibroblasts . . . . . . . . . . 197 Robert M. McCombs and Matilda Benyesh-Melnick and J. Pierre Brunschwig The Use of Millipore Filters in Ultrastructural Studies of Cell Cultures and Viruses . . . . . . . . . . . . . . 231 Jack Rosenbluth Obliquely Striated Muscle . . . . . . . 245 Ronald Hancock and Harold Amos Nuclear binding of exogenous histones by L cells at low pH . . . . . . . . . . . ?? Winfield S. Morgan Ductal Excretion of Neutral Red Lysosomes in the Mouse Pancreas . . . . 261 Don W. Fawcett The Sporadic Occurrence in Cardiac Muscle of Anomalous Z Bands Exhibiting a Periodic Structure Suggestive of Tropomyosin . . . . . . . . . . . . . . 266 C. R. Stocking and L. K. Shumway and T. E. Weier and D. Greenwood Ultrastructure of Chloroplasts Isolated by Nonaqueous Extraction . . . . . . . . 270 Luciano Zamboni and Bernard Gondos Intercellular Bridges and Synchronization of Germ Cell Differentiation During Oogenesis in the Rabbit . . . . . . . . . . . . . . . . . 276 William M. Leach The Thymidine Pool in Grasshopper Neuroblasts During Mitosis . . . . . . . 282
Masando Hayashi and Tsuranobu Shirahama and Alan S. Cohen Combined cytochemical and electron microscopic demonstration of $ \beta $-glucuronidase activity in rat liver with the use of a simultaneous coupling azo dye technique . . . . . . . . . . . 289 P. R. Sweeny and R. Bather An Electron Microscopic Study of the Chorioallantoic Membrane Following Infection with Rous Sarcoma Virus . . . 299 Hisashi Shinozuka and Peter J. Goldblatt and Emmanuel Farber The Disorganization of Hepatic Cell Nucleoli Induced by Ethionine and Its Reversal by Adenine . . . . . . . . . . 313 Elliott Robbins and Gisela Jentzsch and Anita Micali The Centriole Cycle in Synchronized HeLa Cells . . . . . . . . . . . . . . . . . 329 Rainer Martin and Philip Rosenberg Fine Structural Alterations Associated with Venom Action on Squid Giant Nerve Fibers . . . . . . . . . . . . . . . . . 341 Charles E. Ganote and Jared J. Grantham and Harold L. Moses and Maurice B. Burg and Jack Orloff Ultrastructural Studies of Vasopressin Effect on Isolated Perfused Renal Collecting Tubules of the Rabbit . . . . 355 Charles W. Boone and George S. Harell and Howard E. Bond The Resolution of Mixtures of Viable Mammalian Cells into Homogeneous Fractions by Zonal Centrifugation . . . 369 Pierluigi Gambetti and Nicholas K. Gonatas and Louis B. Flexner The Fine Structure of Puromycin-Induced Changes in Mouse Entorhinal Cortex . . . 379 Alfred M. Elliott and Roger G. Zieg A Golgi Apparatus Associated with Mating in \bionameTetrahymena Pyriformis . . . 391 Sidney N. Klaus The Effect of Colchicine on Mosaic Patterns in Cultured Cells . . . . . . . 399 William A. Jensen Cotton Embryogenesis . . . . . . . . . . 403 B. Allen Flaxman and Marvin A. Lutzner and Eugene J. Van Scott Ultrastructure of Cell Attachment to Substratum in Vitro . . . . . . . . . . 406 Bojan Flaks Formation of Membrane-Glycogen Arrays in Rat Hepatoma Cells . . . . . . . . . . . 410 L. H. Lazarus and O. H. Scherbaum Activity of Ribonuclease, Acid Phosphatase, and Phosphodiesterase in \bionameTetrahymena Pyriformis During Growth . . . . . . . . . . . . . . . . . 415
Yutaka Tashiro and Shiro Matsuura and Takashi Morimoto and Sunao Nagata Extrusion of Nuclear Materials into Cytoplasm in the Posterior Silk Gland Cells of Silkworm, Bombyx Mori . . . . . ?? M. Elizabeth Rogers Ribonucleoprotein Particles in the Amphibian Oocyte Nucleus . . . . . . . . 421 Martin Hagopian and David Spiro The Filament Lattice of Cockroach Thoracic Muscle . . . . . . . . . . . . 433 M. Kumegawa and M. Cattoni and George G. Rose Electron Microscopy of Oral Cells in Vitro . . . . . . . . . . . . . . . . . 443 M. Locke and Janet V. Collins Protein Uptake into Multivesicular Bodies and Storage Granules in the Fat Body of an Insect . . . . . . . . . . . 453 Agnese Brega and Arturo Falaschi and Luigi De Carli and Mario Pavan Studies on the Mechanism of Action of Pederine . . . . . . . . . . . . . . . . 485 Joachim R. Sommer and Edward A. Johnson Cardiac Muscle . . . . . . . . . . . . . 497 A. M. Stuart and P. Satir Morphological and Functional Aspects of an Insect Epidermal Gland . . . . . . . 527 Jacob I. Fabrikant The Kinetics of Cellular Proliferation in Regenerating Liver . . . . . . . . . 551 André Bernard Borle Calcium Metabolism in HeLa Cells and the Effects of Parathyroid Hormone . . . . . 567 M. D. Enger and R. A. Tobey and A. G. Saponara RNA Synthesis in Chinese Hamster Cells 583 Richard W. Sagebiel and Thomas H. Reed Serial Reconstruction of the Characteristic Granule of the Langerhans Cell . . . . . . . . . . . . . . . . . . 595 Zane B. Carothers and Gerald L. Kreitner Studies of Spermatogenesis in the Hepaticae . . . . . . . . . . . . . . . 603 Terry C. Johnson and Michael P. Lerner and Gerald J. Lancz Inhibition of Protein Synthesis in Noninfected L Cells by Partially Purified Interferon Preparations . . . . 617 Cornelis L. Voûte and Hans H. Ussing Some Morphological Aspects of Active Sodium Transport* . . . . . . . . . . . 625 Ronald A. Bergman Uterine Smooth Muscle Fibers in Castrate and Estrogen-Treated Rats . . . . . . . 639 Philias R. Garant Glycogen-Membrane Complexes Within Mouse Striated Muscle Cells . . . . . . . . . 648 Alfred L. Goldberg Protein Synthesis During Work-Induced Growth of Skeletal Muscle . . . . . . . 653 R. G. Kessel Fine Structure of Annulate Lamellae . . 658 J. Pieri and C. Vaugien and M. Trouillier Interpretation Cytophotometrique Des Phenomenes Micronucleaires Au Cours De La Division Binaire Et Des Divisions Pregamiques Chez Paramecium Trichium . . 664
Marianne J. Legato and David Spiro and Glenn A. Langer Ultrastructural Alterations Produced in Mammalian Myocardium by Variation in Perfusate Ionic Composition . . . . . . 1 Peter Barland and Carol Smith and David Hamerman Localization of Hyaluronic Acid in Synovial Cells by Radioautography . . . 13 Alden V. Loud A Quantitative Stereological Description of the Ultrastructure of Normal Rat Liver Parenchymal Cells . . . . . . . . 27 Joseph Wiener and Alden V. Loud and Daniel V. Kimberg and David Spiro A Quantitative Description of Cortisone-Induced Alterations in the Ultrastructure of Rat Liver Parenchymal Cells . . . . . . . . . . . . . . . . . 47 Daniel V. Kimberg and Alden V. Loud and Joseph Wiener Cortisone-Induced Alterations in Mitochondrial Function and Structure . . 63 G. J. Stine Enzyme Activities During the Asexual Cycle of Neurospora Crassa . . . . . . . 81 Nancy J. Lane Distribution of Phosphatases in the Golgi Region and Associated Structures of the Thoracic Ganglionic Neurons in the Grasshopper, \bionameMelanoplus Differentialis . . . . . . . . . . . . . 89 Robert E. Kelly and Robert V. Rice Localization of Myosin Filaments in Smooth Muscle . . . . . . . . . . . . . 105 John Lenard and S. J. Singer Alteration of the Conformation of Proteins in Red Blood Cell Membranes and in Solution by Fixatives Used in Electron Microscopy . . . . . . . . . . 117 Ramzi S. Cotran and Morris J. Karnovsky Ultrastructural Studies on the Permeability of the Mesothelium to Horseradish Peroxidase . . . . . . . . . 123 Alan E. Organ and Eugene C. Bovee and Theodore L. Jahn and Duncan Wigg and James R. Fonseca The Mechanism of the Nephridial Apparatus of Paramecium Mul Timicronucleatum . . . . . . . . . . . . 139 Paul D. Sadowski and Jan W. Steiner Electron Microscopic and Biochemical Characteristics of Nuclei and Nucleoli Isolated from Rat Liver . . . . . . . . 147 Paul D. Sadowski and Janet Alcock Howden Isolation of Two Distinct Classes of Polysomes from a Nuclear Fraction of Rat Liver . . . . . . . . . . . . . . . . . 163 David R. Saunders and Janet Wilson and Cyrus E. Rubin Loss of Absorbed Lipid During Fixation and Dehydration of Jejunal Mucosa . . . 183 D. A. Ollerich An Intramitochondrial Crystalloid in Element III of Rat Chorioallantoic Placenta . . . . . . . . . . . . . . . . 188 Francis J. Manasek Mitosis in Developing Cardiac Muscle . . 191 G. Ruhenstroth-Bauer and Christine Lücke-Huhle Two Populations of Small Lymphocytes . . 196 Howard T. Bonnett The Root Endodermis: Fine Structure and Function . . . . . . . . . . . . . . . . 199
P. G. Bartels and E. J. Pegelow The Action of Sirmate (3,4-Dichlorobenzyl Methylcarbamate) on Chloroplast Ribosomes of \bionameTriticum Vulgare L. Seedlings ?? P. G. Wallace and M. Huang and Anthony W. Linnane The Biogenesis of Mitochondria . . . . . 207 D. Jollow and G. M. Kellerman and Anthony W. Linnane The Biogenesis of Mitochondria . . . . . 221 Hideyuki Tsukada and Yohichi Mochizuki and Tadako Konishi Morphogenesis and Development of Microbodies of Hepatocytes of Rats During Pre- and Postnatal Growth . . . . 231 Romaine R. Bruns and George E. Palade Studies on Blood Capillaries . . . . . . 244 Romaine R. Bruns and George E. Palade Studies on Blood Capillaries . . . . . . 277 Charles J. Flickinger The Effects of Enucleation on the Cytoplasmic Membranes of Amoeba Proteus 300 Jean Gouranton Composition, Structure, Et Mode De Formation Des ConcrÉTions MinÉRales Dans L'Intestin Moyen Des Homopteres Cercopides . . . . . . . . . . . . . . . 316 Herbert M. Dembitzer Digestion and the Distribution of Acid Phosphatase in Blepharisma . . . . . . . 329 Charles R. Hackenbrock Ultrastructural Bases for Metabolically Linked Mechanical Activity in Mitochondria . . . . . . . . . . . . . . 345 F. R. Turner An Ultrastructural Study of Plant Spermatogenesis . . . . . . . . . . . . 370 Günter Brittinger and Rochelle Hirschhorn and Steven D. Douglas and Gerald Weissmann Studies on Lysosomes . . . . . . . . . . 394 Rochelle Hirschhorn and Günter Brittinger and Kurt Hirschhorn and Gerald Weissmann Studies on Lysosomes . . . . . . . . . . 412 Adolph I. Cohen New Evidence Supporting the Linkage to Extracellular Space of Outer Segment Saccules of Frog Cones But Not Rods . . 424 Paul A. Toselli and Frank A. Pepe The Fine Structure of the Ventral Intersegmental Abdominal Muscles of the Insect Rhodnius Prolixus During the Molting Cycle . . . . . . . . . . . . . 445 Paul A. Toselli and Frank A. Pepe The Fine Structure of the Ventral Intersegmental Abdominal Muscles of the Insect Rhodnius Prolixus During the Molting Cycle . . . . . . . . . . . . . 462 Federico Leighton and Brian Poole and Henri Beaufay and Pierre Baudhuin and John W. Coffey and Stanley Fowler and Christian De Duve The Large-Scale Separation of Peroxisomes, Mitochondria, and Lysosomes from the Livers of Rats Injected with Triton Wr-1339 . . . . . . . . . . . . . 482 Everett Anderson Oocyte Differentiation in the Sea Urchin, \bionameArbacia Punctulata, with Particular Reference to the Origin of Cortical Granules and Their Participation in the Cortical Reaction 514 John W. Everingham Attachment of Intranuclear Annulate Lamellae to the Nuclear Envelope . . . . 540 John W. Everingham Intranuclear Annulate Lamellae in Ascidian Embryos . . . . . . . . . . . . 551 Charlotte J. Avers and Micheline Federman The Occurrence in Yeast of Cytoplasmic Granules Which Resemble Microbodies . . 555 Barbara Nichols A Membranous Apparatus in a Flagellate, Tritrichomonas Augusta . . . . . . . . . 559 Sheppard M. Walker and G. Randolph Schrodt Triads in Skeletal Muscle Fibers of $ 19$-Day Fetal Rats . . . . . . . . . . . 564 Joachim R. Sommer and Edward A. Johnson Purkinje Fibers of the Heart Examined with the Peroxidase Reaction . . . . . . 570 Gerard M. Lehrer and Cipora Weiss and Demetra J. Silides and Cecile Lichtman and Moses Furman and Robert F. Mathewson The Quantitative Histochemistry of Supramedullary Neurons of Puffer Fishes 575 Hilton H. Mollenhauer and W. Evans and Clara Kogut Dictyosome Structure in Euglena Gracilis 579 Henry Slayter and Yukio Kiho and Cecil E. Hall and Alexander Rich An Electron Microscopic Study of Large Bacterial Polyribosomes . . . . . . . . 583 D. Siew and S. Klein The Effect of Sodium Chloride on Some Metabolic and Fine Structural Changes During the Greening of Etiolated Leaves 590
B. E. S. Gunning and J. S. Pate and L. G. Briarty Specialized ``Transfer Cells'' in Minor Veins of Leaves and Their Possible Significance in Phloem Translocation . . ?? C. Barros and L. E. Franklin Behavior of the Gamete Membranes During Sperm Entry into the Mammalian Egg . . . ?? Monique Milhaud and George D. Pappas Cilia Formation in the Adult Cat Brain After Pargyline Treatment . . . . . . . 599 Stephen L. Wolfe The Effect of Prefixation on the Diameter of Chromosome Fibers Isolated by the Langmuir Trough-Critical Point Method . . . . . . . . . . . . . . . . . 610 Stanley Bullivant and Werner R. Loewenstein Structure of Coupled and Uncoupled Cell Junctions . . . . . . . . . . . . . . . 621 G. E. Palade and R. R. Bruns Structural Modulations of Plasmalemmal Vesicles . . . . . . . . . . . . . . . . 633 Judson D. Sheridan Electrophysiological Evidence for Low-Resistance Intercellular Junctions in the Early Chick Embryo . . . . . . . 650 Larry Simpson Effect of Acriflavin on the Kinetoplast of Leishmania Tarentolae . . . . . . . . 660 John A. Parsons and Ronald C. Rustad The Distribution of DNA Among Dividing Mitochondria of \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 683 Jared M. Diamond and William H. Bossert Functional Consequences of Ultrastructural Geometry in ``Backwards'' Fluid-Transporting Epithelia . . . . . . . . . . . . . . . 694 G. C. Priestley and R. A. Malt Development of the Metanephric Kidney 703 Patricia L. Blanton and James Martin and Sol Haberman Pinocytotic Response of Circulating Erythrocytes to Specific Blood Grouping Antibodies . . . . . . . . . . . . . . . 716 L. Warren and M. C. Glick Membranes of Animal Cells . . . . . . . 729 Robert M. Kodama and Henry Tedeschi Studies on the Permeability of Calf Thymus Nuclei Isolated in Sucrose . . . 747 Sophie Guttes and Edmund Guttes Regulation of DNA Replication in the Nuclei of the Slime Mold \bionamePhysarum Polycephalum . . . . . 761 Jack Van't Hof Control of Cell Progression Through the Mitotic Cycle by Carbohydrate Provision 773 Eveline E. Schneeberger-Keeley and Morris J. Karnovsky The Ultrastructural Basis of Alveolar-Capillary Membrane Permeability to Peroxidase Used As a Tracer . . . . . 781 Neil C. R. Merrillees The Nervous Environment of Individual Smooth Muscle Cells of the Guinea Pig Vas Deferens . . . . . . . . . . . . . . 794 R. D. Smith and F. Deinhardt Unique Cytoplasmic Membranes in Rous Sarcoma Virus-Induced Tumors of a Subhuman Primate . . . . . . . . . . . . 819 S. Goldhor Protein: Lipid Ratios of Liver Mitochondria During Development . . . . 823 Richard D. Allen A Reinvestigation of Cross-Sections of Cilia . . . . . . . . . . . . . . . . . 825 Robert H. Holdsworth The Presence of a Crystalline Matrix in Pyrenoids of the Diatom, Achnanthes Brevipes . . . . . . . . . . . . . . . . 831
Arnold M. Seligman and Morris J. Karnovsky and Hannah L. Wasserkrug and Jacob S. Hanker Nondroplet Ultrastructural Demonstration of Cytochrome Oxidase Activity with a Polymerizing Osmiophilic Reagent, Diaminobenzidine (Dab) . . . . . . . . . 1 E. L. Benedetti and P. Emmelot Hexagonal Array of Subunits in Tight Junctions Separated from Isolated Rat Liver Plasma Membranes . . . . . . . . . 15 James Cronshaw and Katherine Esau P Protein in the Phloem of Cucurbita . . 25 Vivianne T. Nachmias Further Electron Microscope Studies on Fibrillar Organization of the Ground Cytoplasm of Chaos Chaos . . . . . . . . 40 Harunori Ishikawa Formation of Elaborate Networks of T-System Tubules in Cultured Skeletal Muscle with Special Reference to the T-System Formation . . . . . . . . . . . 51 Joseph T. Bagnara and John D. Taylor and Mac E. Hadley The Dermal Chromatophore Unit . . . . . 67 A. E. Vatter and O. K. Reiss and Joyce K. Newman and Karin Lindquist and Elly Groeneboer Enzymes of the Lung . . . . . . . . . . 80 Nancy A. Staley and Ellis S. Benson The Ultrastructure of Frog Ventricular Cardiac Muscle and Its Relationship to Mechanisms of Excitation-Contraction Coupling . . . . . . . . . . . . . . . . 99 Philip W. Brandt and John P. Reuben and Harry Grundfest Correlated Morphological and Physiological Studies on Isolated Single Muscle Fibers . . . . . . . . . . . . . 115 Jean-Claude Wanson and Pierre Drochmans Rabbit Skeletal Muscle Glycogen . . . . 130 N. Steele Scott and Vinod C. Shah and Robert M. Smillie Synthesis of Chloroplast DNA in Isolated Chloroplasts . . . . . . . . . . . . . . 151 Carl Schnaitman and John W. Greenawalt Enzymatic Properties of the Inner and Outer Membranes of Rat Liver Mitochondria . . . . . . . . . . . . . . 158 María Teresa Sabatini and Reinaldo Dipolo and Raimundo Villegas Adenosine Triphosphatase Activity in the Membranes of the Squid Nerve Fiber . . . 176 C. E. Devine and F. O. Simpson Localization of Tritiated Norepinephrine in Vascular Sympathetic Axons of the Rat Intestine and Mesentery by Electron Microscope Radioautography . . . . . . . 184 Sanford L. Palay and Constantino Sotelo and Alan Peters and Paula M. Orkand The Axon Hillock and the Initial Segment 193 Gustav G. Knappeis and Frits Carlsen The Ultrastructure of the M Line in Skeletal Muscle . . . . . . . . . . . . 202 T. Samorajski and J. M. Ordy and W. Zeman and H. J. Curtis Early and Long-Term Effects of Deuteron Irradiation on Cells in the Cerebellum of Adult Mice . . . . . . . . . . . . . 213 Meredith C. Gould Completion of the First Meiotic Division After Fertilization in Urechis Caupo Eggs Despite Inhibition of Protein Synthesis . . . . . . . . . . . . . . . 220 H. Wisniewski and M. L. Shelanski and R. D. Terry Effects of Mitotic Spindle Inhibitors on Neurotubules and Neurofilaments in Anterior Horn Cells . . . . . . . . . . 224 Bojan Flaks Unusual Aspects of Ultrastructural Differentiation in Rat Hepatoma Cells 230 Ann B. Jacobson A Procedure for Isolation of Proplastids from Etiolated Maize Leaves . . . . . . 238 Barbara A. Ehrenreich and Zanvil A. Cohn Fate of Hemoglobin Pincytosed by Macrophages in Vitro . . . . . . . . . . 244 P. A. Cancilla Demonstration of the Langerhans Granule by Lanthanum . . . . . . . . . . . . . . 248 Robert J. Buschmann and A. B. Taylor Extraction of Absorbed Lipid (Linoleic Acid-1-$^{14}$ C) from Rat Intestinal Epithelium During Processing for Electron Microscopy . . . . . . . . . . 252
Gustav Dallner and Anders Bergstrand and Robert Nilsson Heterogeneity of Rough-Surfaced Liver Microsomal Membranes of Adult, Phenobarbital-Treated, and Newborn Rats 257 D. K. Jasper and J. R. Bronk Studies on the Physiological and Structural Characteristics of Rat Intestinal Mucosa . . . . . . . . . . . 277 James Cronshaw and Katherine Esau P Protein in the Phloem of Cucurbita . . 292 Michael L. Shelanski and Edwin W. Taylor Properties of the Protein Subunit of Central-Pair and Outer-Doublet Microtubules of Sea Urchin Flagella . . 304 M. Weintraub and H. W. J. Ragetli Intracellular Characterization of Bean Yellow Mosaic Virus-Induced Inclusions by Differential Enzyme Digestion . . . . 316 Bernard Tandler and David L. Williamson and Lee Ehrman Unusual Filamentous Structures in the Paragonia of Male \bionameDrosophila . . 329 Walther Stoeckenius and Wolf H. Kunau Further Characterization of Particulate Fractions from Lysed Cell Envelopes of Halobacterium Halobium and Isolation of Gas Vacuole Membranes . . . . . . . . . 337 Allen L. Horwitz and Albert Dorfman Subcelluar Sites for Synthesis of Chondromucoprotein of Cartilage . . . . 358 James B. Boyd and Hans D. Berendes and Hudson Boyd Mass Preparation of Nuclei from the Larval Salivary Glands of \bionameDrosophila Hydei . . . . . . . . 369 Martha E. Fedorko and James G. Hirsch and Zanvil A. Cohn Autophagic Vacuoles Produced in Vitro 377 Martha E. Fedorko and James G. Hirsch and Zanvil A. Cohn Autophagic Vacuoles Produced in Vitro 392 Ursula G. Johnson and Keith R. Porter Fine Structure of Cell Division in Chlamydomonas Reinhardi . . . . . . . . 403 James W. MacInnes and Robert B. Uretz DNA Organization in the Mature Sperm of Several Orthoptera by the Method of Polarized Fluorescence Microscopy . . . 426 Peter K. Hepler and William T. Jackson Microtubules and Early Stages of Cell-Plate Formation in the Endosperm of Haemanthus Katherinae Baker . . . . . . 437 Jane Overton Localized Lanthanum Staining of the Intestinal Brush Border . . . . . . . . 447 L. Gibb and E. R. M. Kay Incorporation of DNA by Cells of the Ehrlich-LettrÉ Ascites Carcinoma . . . . 452 A. C. Esterhuizen and T. L. B. Spriggs and J. D. Lever Axon Beadings in Autonomic Cholinergic Nerves . . . . . . . . . . . . . . . . . 454 Frank Wunderlich and Werner W. Franke Structure of Macronuclear Envelopes of \bionameTetrahymena Pyriformis in the Stationary Phase of Growth . . . . . . . 458 L. Orci and A. Junod and R. Pictet and A. E. Renold and C. Rouiller Granulolysis in a Cells of Endocrine Pancreas in Spontaneous and Experimental Diabetes in Animals . . . . . . . . . . 462 W. B. Amos and A. V. Grimstone Intercisternal Material in the Golgi Body of Trichomonas . . . . . . . . . . 466 Fred R. Rickson Nuclear and Cytoplasmic Tubules in Cortical Cells of Leaf Beltian Bodies 471
Bozidar Djordjevic and Jae Ho Kim Different Lethal Effects of Mitomycin C and Actinomycin D During the Division Cycle of HeLa Cells . . . . . . . . . . 477 Sverker Eneström and Anders Hamberger Respiration and Mitochondrial Content in Single Neurons of the Supraoptic Nucleus 483 Bruce S. McEwen and Bernice Grafstein Fast and Slow Components in Axonal Transport of Protein . . . . . . . . . . 494 S. T. Takats Radioautographic Localization of Deoxythymidine Triphosphate in \bionameTradescantia Pollen Grains During DNA Synthesis . . . . . . . . . . 509 Steven E. Kornguth and Lawrence G. Tomasi Changes in the Distribution of a Histone in Dorsal Root Ganglion Neurons During Development . . . . . . . . . . . . . . 515 George W. Cooper and Darwin J. Prockop Intracellular Accumulation of Protocollagen and Extrusion of Collagen by Embryonic Cartilage Cells . . . . . . 523 H. Ishikawa and R. Bischoff and H. Holtzer Mitosis and Intermediate-Sized Filaments in Developing Skeletal Muscle . . . . . 538 A. Jamakosmanovi\'c and W. R. Loewenstein Intercellular Communication and Tissue Growth . . . . . . . . . . . . . . . . . 556 Edward Koenig A Method for Determining Total Protein of Isolated Cellular Elements and Corresponding Tritium Radioactivity . . 562 Yutaka Tashiro and Takashi Morimoto and Shiro Matsuura and Sunao Nagata Studies on the Posterior Silk Gland of the Silkworm, Bombyx Mori . . . . . . . 574 Shiro Matsuura and Takashi Morimoto and Sunao Nagata and Yutaka Tashiro Studies on the Posterior Silk Gland of the Silkworm, Bombyx Mori . . . . . . . 589 Takashi Morimoto and Shiro Matsuura and Sunao Nagata and Yutaka Tashiro Studies on the Posterior Silk Gland of the Silkworm, Bombyx Mori . . . . . . . 604 James G. Hirsch and Martha E. Fedorko Ultrastructure of Human Leukocytes After Simultaneous Fixation with Glutaraldehyde and Osmium Tetroxide and ``Postfixation'' in Uranyl Acetate . . . 615 James G. Hirsch and Martha E. Fedorko and Zanvil A. Cohn Vesicle Fusion and Formation at the Surface of Pinocytic Vacuoles in Macrophages . . . . . . . . . . . . . . 629 Robert L. Schultz and Norman M. Case Microtubule Loss with Acrolein and Bicarbonate-Containing Fixatives . . . . 633 Asao Hirano A Confirmation of the Oligodendroglial Origin of Myelin in the Adult Rat . . . 637 H. Uno and K. Adachi and F. Hu Enzyme Activities of the Epithelial Outgrowth of the Hair Follicles in Tissue Culture . . . . . . . . . . . . . 640
R. G. Kessel and W. R. Panje Organization and Activity in the Pre- and Postovulatory Follicle of Necturus Maculosus . . . . . . . . . . . . . . . 1 Eldon H. Newcomb and Martin W. Steer and Peter K. Hepler and William P. Wergin An Atypical Crista Resembling a ``Tight Junction'' in Bean Root Mitochondria . . 35 Victor J. Matukas and George A. Krikos Evidence for Changes in Protein Polysaccharide Associated with the Onset of Calcification in Cartilage . . . . . 43 Carl M. Feldherr Nucleocytoplasmic Exchanges During Early Interphase . . . . . . . . . . . . . . . 49 Richard S. Thomas and John W. Greenawalt Microincineration, Electron Microscopy, and Electron Diffraction of Calcium Phosphate-Loaded Mitochondria . . . . . 55 Peter Satir Studies on Cilia . . . . . . . . . . . . 77 Blair Bowers and Edward D. Korn The Fine Structure of \bionameAcanthamoeba Castellanii . . . . 95 R. Soeiro and M. H. Vaughan and J. R. Warner and J. E. Darnell The Turnover of Nuclear DNA-Like RNA in HeLa Cells . . . . . . . . . . . . . . . 112 W. Eugene Foor Zygote Formation in Ascaris Lumbricoides (Nematoda) . . . . . . . . . . . . . . . 119 George Odland and Russell Ross Human Wound Repair . . . . . . . . . . . 135 Russell Ross and George Odland Human Wound Repair . . . . . . . . . . . 152 Richard W. Young and Bernard Droz The Renewal of Protein in Retinal Rods and Cones . . . . . . . . . . . . . . . 169 Yechezkiel Stein and Christopher Widnell and Olga Stein Acylation of Lysophosphatides by Plasma Membrane Fractions of Rat Liver . . . . 185 D. W. Stanley and H. O. Hultin Mechanism of Emptying of Skeletal Muscle Cell Segments . . . . . . . . . . . . . ?? K. Cheng-Minoda and J. Davidowitz and A. Liebowitz and G. M. Breinin Fine Structure of Extraocular Muscle in Rabbit . . . . . . . . . . . . . . . . . 193 R. J. Podolsky Deposit Formation in Muscle Fibers Following Contraction in the Presence of Lead . . . . . . . . . . . . . . . . . . 197 Donald Orlic The Use Of$^{55}$ Fe in High-Resolution Radioautography of Developing Red Cells 201 Barry Friedman and Pierre Blais and Patricia Shaffer Fine Structure of Millipore Filters . . 208 Awtar Krishan and Dora Hsu and Patricia Hutchins Hypertrophy of Granular Endoplasmic Reticulum and Annulate Lamellae in Earle's L Cells Exposed to Vinblastine Sulfate . . . . . . . . . . . . . . . . 211 S. S. Spicer and J. H. Hardin and W. B. Greene Nuclear Precipitates in Pyroantimonate-Osmium Tetroxide-Fixed Tissues . . . . . . . . . . . . . . . . 216 David R. Wolstenholme and Igor B. Dawid A Size Difference Between Mitochondrial DNA Molecules of Urodele and Anuran Amphibia . . . . . . . . . . . . . . . . 222
Jiro Matsumoto and Masataka Obika Morphological and Biochemical Characterization of Goldfish Erythrophores and Their Pterinosomes . . 233 N. Nanninga Structural Features of Mesosomes (Chondrioids) of Bacillus Subtilis After Freeze-Etching . . . . . . . . . . . . . 251 Catharine P. Fussell Cytoplasmic Label Following Tritiated Thymidine Treatment of \bionameAllium Cepa L. Roots . . . . . . . . . . . . . 264 Dorothy Ford Bainton and Marilyn G. Farquhar Differences in Enzyme Content of Azurophil and Specific Granules of Polymorphonuclear Leukocytes . . . . . . 286 Dorothy Ford Bainton and Marilyn G. Farquhar Differences in Enzyme Content of Azurophil and Specific Granules of Polymorphonuclear Leukocytes . . . . . . 299 Paul R. Burton and Donald G. Dusanic Fine Structure and Replication of the Kinetoplast of Trypanosoma Lewisi . . . 318 P. L. Webster and D. Davidson Evidence from Thymidine-$^3$ H-Labeled Meristems of \bionameVicia Faba of Two Cell Populations . . . . . . . . . . . . 332 Frank J. Longo and Everett Anderson The Fine Structure of Pronuclear Development and Fusion in the Sea Urchin, \bionameArbacia Punctulata . . . 339 Renée Charret and Jean André La Synth\`ESe De L'Adn Mitochondrial Chez \bionameTetrahymena Pyriformis . . 369 L. Packer and J. M. Wrigglesworth and P. A. G. Fortes and B. C. Pressman Expansion of the Inner Membrane Compartment and Its Relation to Mitochondrial Volume and Ion Transport 382 Haim Ginsburg and David Lagunoff Aggregation and Transformation of Rat Lymphocytes on Rat Embryo Monolayers . . 392 David Prescott and Lester Goldstein Proteins in Nucleocytoplasmic Interactions . . . . . . . . . . . . . . 404 E. F. Howard and W. Plaut Chromosomal DNA Synthesis in \bionameDrosophila Melanogaster . . . . 415 George G. Rose and M. Kumegawa and M. Cattoni The Circumfusion System for Multipurpose Culture Chambers . . . . . . . . . . . . 430 Brenda Eisenberg and Robert S. Eisenberg Selective Disruption of the Sarcotubular System in Frog Sartorius Muscle . . . . 451 Sheppard M. Walker and G. Randolph Schrodt and Maxine Bingham Electron Microscope Study of the Sarcoplasmic Reticulum at the Z Line Level in Skeletal Muscle Fibers of Fetal and Newborn Rats . . . . . . . . . . . . 469 T. Hando and D. M. Okada and L. Zamboni Atypical Cilia in Human Endometrium . . 475 Charles B. Metz and M. Virginia Cone and Jeanne Bryant Effect of Proteolytic Enzymes on the Ultrastructure of Antibody-Treated Sea Urchin Eggs . . . . . . . . . . . . . . 481 Peddrick Weis Confronting Subsurface Cisternae in Chick Embryo Spinal Ganglia . . . . . . 485 Dianne Fristrom Cellular Degeneration in Wing Development of the Mutant Vestigial of \bionameDrosophila Melanogaster . . . . 488 E. L. Rodriguez Echandia and R. S. Piezzi Microtubules in the Nerve Fibers of the Toad Bufo Arenarum Hensel . . . . . . . 491
J. A. Beaulaton Modifications Ultrastructurales Des Cellules SÉCrÉTrices De La Glande Prothoracique De Vers \`A Soie Au Cours Des Deux Derniers ÂGes Larvaires . . . . 501 Kathryn V. Holmes and Purnell W. Choppin On the Role of Microtubules in Movement and Alignment of Nuclei in Virus-Induced Syncytia . . . . . . . . . . . . . . . . 526 Robert H. Warren The Effect of Colchicine on Myogenesis in Vivo in Rana Pipiens and Rhodnius Prolixus (Hemiptera) . . . . . . . . . . 544 G. E. Stone Synchronized Cell Division in \bionameTetrahymena Pyriformis Following Inhibition with Vinblastine . . . . . . 556 S. L. Wissig and D. O. Graney Membrane Modifications in the Apical Endocytic Complex of Ileal Epithelial Cells . . . . . . . . . . . . . . . . . 564 James D. Jamieson and George E. Palade Intracellular Transport of Secretory Proteins in the Pancreatic Exocrine Cell 580 James D. Jamieson and George E. Palade Intracellular Transport of Secretory Proteins in the Pancreatic Exocrine Cell 589 Alan Peters and Charmian C. Proskauer and Ita R. Kaiserman-Abramof The Small Pyramidal Neuron of the Rat Cerebral Cortex . . . . . . . . . . . . 604 N. Ikemoto and S. Kitagawa and A. Nakamura and J. Gergely Electron Microscopic Investigations of Actomyosin As a Function of Ionic Strength . . . . . . . . . . . . . . . . 620 K. Tokuyasu and S. C. Madden and L. J. Zeldis Fine Structural Alterations of Interphase Nuclei of Lymphocytes Stimulated to Growth Activity in Vitro 630 Frank D. Vasington and John W. Greenawalt Osmotically Lysed Rat Liver Mitocondria 661 Gilbert Vaes On the Mechanisms of Bone Resorption . . 676 H. W. Israel and M. M. Salpeter and F. C. Steward The Incorporation of Radioactive Proline into Cultured Cells . . . . . . . . . . 698 Sin Hang Lee and Richard M. Torack Electron Microscope Studies of Glutamic Oxalacetic Transaminase in Rat Liver Cell . . . . . . . . . . . . . . . . . . 716 Sin Hang Lee and Richard M. Torack A Biochemical and Histochemical Study of Glutamic Oxalacetic Transaminase Activity of Rat Hepatic Mitochondria Fixed in Situ and in Vitro . . . . . . . 725 William H. Dobelle and Michael Beer Chemically Cleaved Graphite Support Films for Electron Microscopy . . . . . 733 R. G. Kessel and H. W. Beams Intranucleolar Membranes and Nuclear-Cytoplasmic Exchange in Young Crayfish Oocytes . . . . . . . . . . . . 735 Yoshiaki Nonomura Myofilaments in Smooth Muscle of Guinea Pig's \bionameTaenia Coli . . . . . . . 741 Donald B. Fisher Localization of Endogenous RNA Polymerase Activity in Frozen Sections of Plant Tissues . . . . . . . . . . . . 745 Masamichi Aikawa and Richard L. Beaudoin Studies on Nuclear Division of a Malarial Parasite Under Pyrimethamine Treatment . . . . . . . . . . . . . . . 749 Magdalena Reissig and Anthony V. Colucci Localization of Glycogen in the Cestode, Hymenolepis Diminuta . . . . . . . . . . 754
Donald R. DiBona and Mortimer M. Civan and Alexander Leaf The Anatomic Site of the Transepithelial Permeability Barriers of Toad Bladder 1 Peter O. Kohler and Philip M. Grimley and Bert W. O'malley Estrogen-Induced Cytodifferentiation of the Ovalbumin-Secreting Glands of the Chick Oviduct . . . . . . . . . . . . . 8 David M. Phillips Exceptions to the Prevailing Pattern of Tubules (9 + 9 + 2) in the Sperm Flagella of Certain Insect Species . . . 28 Scott E. Dietert and Terence J. Scallen An Ultrastructural and Biochemical Study of the Effects of Three Inhibitors of Cholesterol Biosynthesis Upon Murine Adrenal Gland and Testis . . . . . . . . 44 D. Doyle and H. Laufer Sources of Larval Salivary Gland Secretion in the Dipteran Chironomus Tentans . . . . . . . . . . . . . . . . 61 Ruth Ellen Bulger Use of Potassium Pyroantimonate in the Localization of Sodium Ions in Rat Kidney Tissue . . . . . . . . . . . . . 79 Klaus G. Bensch and Stephen E. Malawista Microtubular Crystals in Mammalian Cells 95 Joe L. Griffin and Marvin N. Stein and Robert E. Stowell Laser Microscope Irradiation of \bionamePhysarum Polycephalum: Dynamic and Ultrastructural Effects . . . . . . 108 James R. Aist The Mitotic Apparatus in Fungi, Ceratocystis Fagacearum and Fusarium Oxysporum . . . . . . . . . . . . . . . 120 Jane Overton A Fibrillar Intercellular Material Between Reaggregating Embryonic Chick Cells . . . . . . . . . . . . . . . . . 136 Howard T. Bonnett Cortical Cell Death During Lateral Root Formation . . . . . . . . . . . . . . . 144 Vivianne T. Nachmias Studies on Streaming . . . . . . . . . . 160 Marvin H. Stromer and D. J. Hartshorne and Helmut Mueller and Robert V. Rice The Effect of Various Protein Fractions on Z- and M-Line Reconstitution . . . . 167 Akio Ito and Ryo Sato Proteolytic Microdissection of Smooth-Surfaced Vesicles of Liver Microsomes . . . . . . . . . . . . . . . 179 Walter J. Hendelman and Richard P. Bunge Radioautographic Studies of Choline Incorporation into Peripheral Nerve Myelin . . . . . . . . . . . . . . . . . 190 J. A. Piper and N. W. Klein The Differential Sensitivity of Cultured Chick Mesodermal Cells to Actinomycin D 209 Robert H. Michell and Samuel J. Pancake and John Noseworthy and Manfred L. Karnovsky Measurement of Rates of Phagocytosis . . 216 Joseph T. Tesar and Harold Koenig and Charles Hughes Hormone Storage Granules in the Beef Anterior Pituitary . . . . . . . . . . . 225 U. Ingrid Richardson and Armen H. Tashjian and Lawrence Levine Establishment of a Clonal Strain of Hepatoma Cells Which Secrete Albumin . . 236 Stephanie Gordon Phillips and David M. Phillips Sites of Nucleolus Production in Cultured Chinese Hamster Cells . . . . . 248 Ivonne Pasquali-Ronchetti The Organization of the Sarcoplasmic Reticulum and T System in the Femoral Muscle of the Housefly, \bionameMusca Domestica . . . . . . . . . . . . . . . 269 Peter B. Moens The Fine Structure of Meiotic Chromosome Pairing in the Triploid, \bionameLilium Tigrinum . . . . . . . . . . . . . . . . 273 Jerome J. Wolken and Robert G. Florida The Eye Structure and Optical System of the Crustacean Copepod, Copilia . . . . 279 Nancy J. Lane Intranuclear Fibrillar Bodies in Actinomycin D-Treated Oocytes . . . . . 286
M. J. Griffin and R. Ber Cell Cycle Events in the Hydrocortisone Regulation of Alkaline Phosphatase in HeLa S$_3$ Cells . . . . . . . . . . . . 297 Stephen A. Ernst and Richard A. Ellis The Development of Surface Specialization in the Secretory Epithelium of the Avian Salt Gland in Response to Osmotic Stress . . . . . . . 305 Shuichi Karasaki The Fine Structure of Proliferating Cells in Preneoplastic Rat Livers During Azo-Dye Carcinogenesis . . . . . . . . . 322 Gertrude W. Hinsch and M. Virginia Cone Ultrastructural Observations of Vitellogenesis in the Spider Crab, \bionameLibinia Emarginata L . . . . . . 336 Richard A. Rifkind and David Chui and Hazel Epler An Ultrastructural Study of Early Morphogenetic Events During the Establishment of Fetal Hepatic Erythropoiesis . . . . . . . . . . . . . 343 Russell Ross and Paul Bornstein The Elastic Fiber . . . . . . . . . . . 366 Jen Yeh and Harold W. Fisher A Diffusible Factor Which Sustains Contact Inhibition of Replication . . . 382 Alan E. Organ and Eugene C. Bovee and Theodore L. Jahn The Mechanism of the Nephridial Apparatus of Paramecium Multimicronucleatum . . . . . . . . . . 389 A. Rambourg and W. Hernandez and C. P. Leblond Detection of Complex Carbohydrates in the Golgi Apparatus of Rat Cells . . . . 395 Joel L. Rosenbaum and Kathryn Carlson Cilia Regeneration in \bionameTetrahymena and Its Inhibition by Colchicine . . . . . . . . . . . . . 415 Jean Ross and W. Gerald Robison Unusual Microtubular Patterns and Three-Dimensional Movement of Mealybug Sperm and Sperm Bundles . . . . . . . . 426 G. Benjamin Bouck Extracellular Microtubules . . . . . . . 446 Olga Stein and Yechezkiel Stein Lecithin Synthesis, Intracellular Transport, and Secretion in Rat Liver 461 Charles E. Holt and Elizabeth G. Gurney Minor Components of the DNA of \bionamePhysarum Polycephalum . . . . . 484 L. D. Hodge and E. Robbins and M. D. Scharff Persistence of Messenger RNA Through Mitosis in HeLa Cells . . . . . . . . . 497 Donna F. Kubai and Hans Ris Division in the Dinoflagellate Gyrodinium Cohnii (Schiller) . . . . . . 508 Marco Baggiolini and James G. Hirsch and Christian de Duve Resolution of Granules from Rabbit Heterophil Leukocytes into Distinct Populations by Zonal Sedimentation . . . 529 Peter B. Moens Multiple Core Complexes in Grasshopper Spermatocytes and Spermatids . . . . . . 542 Charles P. Miles and Frank O'Neill $^3$H Labeling Patterns of Permanent Cell Line Chromosomes Showing Pulverization Or Accentuated Secondary Constrictions . . . . . . . . . . . . . 553 Paul F. Parakkal Ultrastructural Changes of the Basal Lamina During the Hair Growth Cycle . . 561 Ivonne Pasquali-Ronchetti and John W. Greenawalt and Ernesto Carafoli On the Nature of the Dense Matrix Granules of Normal Mitochondria . . . . 565 M. Reznik Thymidine-$^3$H Uptake by Satellite Cells of Regenerating Skeletal Muscle 568 Beatriz G. T. Pogo The Effect of N-Acetyl-D-Galactosamine and Amantadine Hydrochloride on Equine Lymphocytes Stimulated with Phytohemagglutinin . . . . . . . . . . . 571 Dieter Ammermann Release of DNA Breakdown Products into the Culture Medium of Stylonychia Mytilus Exconjugants (Protozoa, Ciliata) During the Destruction of the Polytene Chromosomes . . . . . . . . . . . . . . 576 Arnaldo Lasansky Basal Junctions at Synaptic Endings of Turtle Visual Cells . . . . . . . . . . 577
J. Groniowski and W. Biczyskowa and M. Walski Electron Microscope Studies on the Surface Coat of the Nephron . . . . . . 585 Umberto Muscatello and Ernesto Carafoli The Oxidation of Exogenous and Endogenous Cytochrome C in Mitochondria 602 Nessly Craig and Lester Goldstein Studies on the Origin of Ribosomes in Amoeba Proteus . . . . . . . . . . . . . 622 A. Lord and J.-G. Lafontaine The Organization of the Nucleolus in Meristematic Plant Cells . . . . . . . . 633 M. W. Brightman and T. S. Reese Junctions Between Intimately Apposed Cell Membranes in the Vertebrate Brain 648 Elliott Robbins and Gisela Jentzsch Ultrastructural Changes in the Mitotic Apparatus at the Metaphase-To-Anaphase Transition . . . . . . . . . . . . . . . 678 W. G. Forssmann and L. Orci and R. Pictet and A. E. Renold and C. Rouiller The Endocrine Cells in the Epithelium of the Gastrointestinal Mucosa of the Rat 692 Richard D. Allen The Morphogenesis of Basal Bodies and Accessory Structures of the Cortex of the Ciliated Protozoan \bionameTetrahymena Pyriformis . . . . . 716 Donald Svoboda and Daniel Azarnoff and Janardan Reddy Microbodies in Experimentally Altered Cells . . . . . . . . . . . . . . . . . 734 Jacques Padawer Uptake of Colloidal Thorium Dioxide by Mast Cells . . . . . . . . . . . . . . . 747 Lloyd Silverman and David Glick The Reactivity and Staining of Tissue Proteins with Phosphotungstic Acid . . . 761 Lloyd Silverman and Berit Schreiner and David Glick Measurement of Thickness Within Sections by Quantitative Electron Microscopy . . 768 Lloyd Silverman and David Glick Measurement of Protein Concentration by Quantitative Electron Microscopy . . . . 773 Linda A. Hufnagel Cortical Ultrastructure of Paramecium Aurelia . . . . . . . . . . . . . . . . 779 Terence J. Scallen and Scott E. Dietert The Quantitative Retention of Cholesterol in Mouse Liver Prepared for Electron Microscopy by Fixation in a Digitonin-Containing Aldehyde Solution 802 G. A. de Zoeten and G. Gaard Possibilities for Inter- and Intracellular Translocation of Some Icosahedral Plant Viruses . . . . . . . 814 Alain Perrelet and Fritz Baumann Evidence for Extracellular Space in the Rhabdome of the Honeybee Drone Eye . . . 825 Kimie Fukuyama and William L. Epstein Sulfur-Containing Proteins and Epidermal Keratinization . . . . . . . . . . . . . 830 Ernest Feleppa Holographic, Motion-Induced-Contrast Images . . . . . . . . . . . . . . . . . 838 Günter Brittinger and Rochelle Hirschhorn and Kurt Hirschhorn and Gerald Weissmann Effect of Pokeweed Mitogen (Pwm) on Lymphocyte Lysosomes . . . . . . . . . . 843 J. L. Pauly and G. A. Caron and R. R. Suskind Blast Transformation of Lymphocytes from Guinea Pigs, Rats, and Rabbits Induced by Mercuric Chloride in Vitro . . . . . 847 Richard L. McCarl and Robert C. Shaler The Effects of Actinomycin D on Protein Synthesis and Beating in Cultured Rat Heart Cells . . . . . . . . . . . . . . 850 H. J. Wilson Arms and Bridges on Microtubules in the Mitotic Apparatus . . . . . . . . . . . 854 Peter A. Nickerson and Joseph C. Curtis Concentric Whorls of Rough Endoplasmic Reticulum in Adrenocortical Cells of the Mongolian Gerbil . . . . . . . . . . . . 859 Eric Holtzman and Edith R. Peterson Uptake of Protein by Mammalian Neurons 863 Carolyn D. Mitchell Preservation of the Lipids of the Human Erythrocyte Stroma During Fixation and Dehydration for Electron Microscopy . . 869
M. M. Salpeter and L. Bachmann and E. E. Salpeter Resolution in Electron Microscope Radioautography . . . . . . . . . . . . 1 G. C. Budd and M. M. Salpeter The Distribution of Labeled Norepinephrine Within Sympathetic Nerve Terminals Studied with Electron Microscope Radioautography . . . . . . . 21 F. Clementi and G. E. Palade Intestinal Capillaries . . . . . . . . . 33 H. Clarke Anderson Vesicles Associated with Calcification in the Matrix of Epiphyseal Cartilage 59 J. G. Abuelo and Dorothy E. Moore The Human Chromosome . . . . . . . . . . 73 Carlos J. Tandler and Alberto J. Solari Nucleolar Orthophosphate Ions . . . . . 91 R. M. Brown Observations on the Relationship of the Golgi Apparatus to Wall Formation in the Marine Chrysophycean Alga, Pleurochrysis Scherffelii Pringsheim . . . . . . . . . 109 C. S. Song and W. Rubin and A. B. Rifkind and A. Kappas Plasma Membranes of the Rat Liver . . . 124 R. E. Kane and R. E. Stephens A Comparative Study of the Isolation of the Cortex and the Role of the Calcium-Insoluble Protein in Several Species of Sea Urchin Egg . . . . . . . 133 David W. Rooney and John J. Eiler Effects of Division-Synchronizing Hypoxic and Hyperthermic Shocks Upon \bionameTetrahymena Respiration and Intracellular ATP Concentration . . . . 145 S. L. Howell and C. J. Fink and P. E. Lacy Isolation and Properties of Secretory Granules from Rat Islets of Langerhans 154 Marie H. Greider and S. L. Howell and P. E. Lacy Isolation and Properties of Secretory Granules from Rat Islets of Langerhans 162 S. L. Howell and D. A. Young and P. E. Lacy Isolation and Properties of Secretory Granules from Rat Islets of Langerhans 167 Margherita Willems and Maria Penman and Sheldon Penman The Regulation of RNA Synthesis and Processing in the Nucleolus During Inhibition of Protein Synthesis . . . . 177 Richard Bischoff and Howard Holtzer Mitosis and the Processes of Differentiation of Myogenic Cells in Vitro . . . . . . . . . . . . . . . . . 188 John R. Gibbins and Lewis G. Tilney and Keith R. Porter Microtubules in the Formation and Development of the Primary Mesenchyme in \bionameArbacia Punctulata . . . . . . . 201 Lewis G. Tilney and John R. Gibbins Microtubules in the Formation and Development of the Primary Mesenchyme in \bionameArbacia Punctulata . . . . . . . 227 W. David Troughton and Jerry S. Trier Paneth and Goblet Cell Renewal in Mouse Duodenal Crypts . . . . . . . . . . . . 251 Daniel S. Friend Cytochemical Staining of Multivesicular Body and Golgi Vesicles . . . . . . . . 269 Hisashi Shinozuka and Emmanuel Farber Reformation of Nucleoli After Ethione-Induced Fragmentation in the Absence of Significant Protein Synthesis 280 J. L. S. Cobb and Terence Bennett A Study of Nexuses in Visceral Smooth Muscle . . . . . . . . . . . . . . . . . 287 Tom Elsdale and Robert Foley Morphogenetic Aspects of Multilayering in Petri Dish Cultures of Human Fetal Lung Fibroblasts . . . . . . . . . . . . 298 John F. Thomson and Duane A. Habeck and Sharron L. Nance and Karen L. Beetham Ultrastructural and Biochemical Changes in Brown Fat in Cold-Exposed Rats . . . 312 Noel T. Florendo Ribosome Substructure in Intact Mouse Liver Cells . . . . . . . . . . . . . . 335 J. Ramus Dimorphic Pit Connections in the Red Alga Pseudogloiophloea . . . . . . . . . 340 Paul F. Parakkal Involvement of Macrophages in Collagen Resorption . . . . . . . . . . . . . . . 345
Peter R. Dallman and Gustav Dallner and Anders Bergstrand and Lars Ernster Heterogeneous Distribution of Enzymes in Submicrosomal Membrane Fragments . . . . 357 Charles W. Boone and Lincoln E. Ford and Howard E. Bond and Donald C. Stuart and Dianne Lorenz Isolation of Plasma Membrane Fragments from HeLa Cells . . . . . . . . . . . . 378 R. A. Goyer and R. Krall Ultrastructural Transformation in Mitochondria Isolated from Kidneys of Normal and Lead-Intoxicated Rats . . . . 393 Marianne J. Legato and Glenn A. Langer The Subcellular Localization of Calcium Ion in Mammalian Myocardium . . . . . . 401 Yasukazu Tanaka Effect of the Ruby Laser Microbeam on Mitochondria of Kb Cells Supravitally Stained by Pinacyanol . . . . . . . . . 424 Edgar F. Carell Studies on Chloroplast Development and Replication in Euglena . . . . . . . . . 431 Kin-Ichi Ohkawa and Molly T. Vogt and Emmanuel Farber Unusually High Mitochondrial Alpha Glycerophosphate Dehydrogenase Activity in Rat Brown Adipose Tissue . . . . . . 441 David Brandes and Elsa Anton An Electron Microscopic Cytochemical Study of Macrophages During Uterine Involution . . . . . . . . . . . . . . . 450 Peter M. Robinson A Cholinergic Component in the Innervation of the Longitudinal Smooth Muscle of the Guinea Pig Vas Deferens 462 Bernard Tandler and Robert A. Erlandson and Archie L. Smith and Ernest L. Wynder Riboflavin and Mouse Hepatic Cell Structure and Function . . . . . . . . . 477 Marko Zalokar Intracellular Centrifugal Separation of Organelles in \bionamePhycomyces . . . . 494 Moshe Siev and Robert Weinberg and Sheldon Penman The Selective Interruption of Nucleolar RNA Synthesis in HeLa Cells by Cordycepin . . . . . . . . . . . . . . . 510 Federico Leighton and Brian Poole and Paul B. Lazarow and Christian De Duve The Synthesis and Turnover of Rat Liver Peroxisomes . . . . . . . . . . . . . . 521 Brian Poole and Federico Leighton and Christian De Duve The Synthesis and Turnover of Rat Liver Peroxisomes . . . . . . . . . . . . . . 536 George C. Hill and Winston A. Anderson Effects of Acriflavine on the Mitochondria and Kinetoplast of Crithidia Fasciculata . . . . . . . . . 547 Jared J. Grantham and Charles E. Ganote and Maurice B. Burg and Jack Orloff Paths of Transtubular Water Flow in Isolated Renal Collecting Tubules . . . 562 Thomas Bibring and Jane Baxandall Immunochemical Studies of 22S Protein from Isolated Mitotic Apparatus . . . . 577 Hans D. Berendes and James B. Boyd Structural and Functional Properties of Polytene Nuclei Isolated from Salivary Glands of \bionameDrosophila Hydei . . . 591 Joel L. Rosenbaum and John E. Moulder and David L. Ringo Flagellar Elongation and Shortening in Chlamydomonas . . . . . . . . . . . . . 600 B. Daneholt and J.-E. Edström The DNA Base Composition of Individual Chromosomes and Chromosome Segments from Chironomus Tentans . . . . . . . . . . . 620 Srinivasan Rajalakshmi and W. Robert Adams and Robert E. Handschumacher Isolation and Characterization of Low Density Structures from Orotic Acid-Induced Fatty Livers . . . . . . . 625 R. Barton Investigation of Negatively Stained Plant Flagellar Microtubules by Optical Diffraction . . . . . . . . . . . . . . 637 R. A. Florentin and B. H. Choi and K. T. Lee and W. A. Thomas Stimulation of DNA Synthesis and Cell Division in Vitro by Serum from Cholesterol-Fed Swine . . . . . . . . . 641 C. A. R. Boyd and D. S. Parsons The Fine Structure of the Microvilli of Isolated Brush Borders of Intestinal Epithelial Cells . . . . . . . . . . . . 646 Joseph B. Warshaw Cellular Energy Metabolism During Fetal Development . . . . . . . . . . . . . . 651 Robert M. Lavker Fine Structure of Mucus Granules in Rumen Epithelium . . . . . . . . . . . . 657 Leroy Kuehl Effect of Various Inhibitors on Nuclear Protein Synthesis in Rat Liver . . . . . 660
A. W. Rogers and Z. Darzynkiewicz and M. M. Salpeter and K. Ostrowski and E. A. Barnard Quantitative Studies on Enzymes in Structures in Striated Muscles by Labeled Inhibitor Methods . . . . . . . 665 A. W. Rogers and E. A. Barnard Quantitative Studies on Enzymes in Structures in Striated Muscles by Labeled Inhibitor Methods . . . . . . . 686 Eleanor C. Adams and Arthur T. Hertig Studies on the Human Corpus Luteum . . . 696 Eleanor C. Adams and Arthur T. Hertig Studies on the Human Corpus Luteum . . . 716 David A. Sell and Edward S. Reynolds Liver Parenchymal Cell Injury . . . . . 736 Avraham Amsterdam and Itzhak Ohad and Michael Schramm Dynamic Changes in the Ultrastructure of the Acinar Cell of the Rat Parotid Gland During the Secretory Cycle . . . . . . . 753 Eugene Marquet and Harold John Sobel Crystalline Inclusions in the Nuclear Envelope and Granular Endoplasmic Reticulum of the Fish Spinal Cord . . . 774 Blair Bowers and Edward D. Korn The Fine Structure of \bionameAcanthamoeba Castellanii (Neff Strain) . . . . . . . . . . . . . . . . 786 R. H. Bottomley and A. L. Trainer and M. J. Griffin Enzymatic and Chromosomal Characterization of HeLa Variants . . . 806 Takami Oka and Robert T. Schimke Interaction of Estrogen and Progesterone in Chick Oviduct Development . . . . . . 816 Sonia Rude and Richard E. Coggeshall and Lucas S. Van Orden Chemical and Ultrastructural Identification of $5$-Hydroxytryptamine in an Identified Neuron . . . . . . . . 832 S. Schiaffino and A. Margreth Coordinated Development of the Sarcoplasmic Reticulum and T System During Postnatal Differentiation of Rat Skeletal Muscle . . . . . . . . . . . . 855 James A. Robb Maintenance of Imaginal Discs of \bionameDrosophila Melanogaster in Chemically Defined Media . . . . . . . . 876 G. C. Priestley and R. A. Malt Membrane-Bound Ribosomes in Kidney . . . 886 John M. Arnold Cleavage Furrow Formation in a Telolecithal Egg (\bionameLoligo Pealii) 894 Myra Jagendorf-Elfvin and Eva Eliasson Reversible Changes in the Ultrastructure of Chang Liver Cell Mitochondria Following Incubation of the Cells in a Glutamine-Deficient Medium . . . . . . . 905 Carole Kelley Wall Projections in the Sporophyte and Gametophyte of Sphaerocarpos . . . . . . 910 Mary Bell Langerhans Granules in Fetal Keratinocytes . . . . . . . . . . . . . 914 Lucien G. Caro A Common Source of Difficulty in High-Resolution Radioautography . . . . 918
Don W. Fawcett and N. Scott McNutt The Ultrastructure of the Cat Myocardium 1 N. Scott McNutt and Don W. Fawcett The Ultrastructure of the Cat Myocardium 46 Ewald R. Weibel and Willy Stäubli and Hans Rudolf Gnägi and Felix A. Hess Correlated Morphometric and Biochemical Studies on the Liver Cell . . . . . . . 68 Willy Stäubli and Robert Hess and Ewald R. Weibel Correlated Morphometric and Biochemical Studies on the Liver Cell . . . . . . . 92 Paul F. Kruse and Wilbur Whittle and Ed Miedema Mitotic and Nonmitotic Multiple-Layered Perfusion Cultures . . . . . . . . . . . 113 M. M. Salpeter Electron Microscope Radioautography As a Quantitative Tool in Enzyme Cytochemistry . . . . . . . . . . . . . 122 A. M. Kelly and S. I. Zacks The Histogenesis of Rat Intercostal Muscle . . . . . . . . . . . . . . . . . 135 A. M. Kelly and S. I. Zacks The Fine Structure of Motor Endplate Morphogenesis . . . . . . . . . . . . . 154 Lewis G. Tilney and Douglas Marsland A Fine Structural Analysis of Cleavage Induction and Furrowing in the Eggs of \bionameArbacia Punctulata . . . . . . . 170 R. G. Kessel and H. W. Beams Annulate Lamellae and ``Yolk Nuclei'' in Oocytes of the Dragonfly, Libellula Pulchella . . . . . . . . . . . . . . . 185 Toku Kanaseki and Ken Kadota The ``Vesicle in a Basket'' . . . . . . 202 Charles R. Hackenbrock and Arnold I. Caplan Ion-Induced Ultrastructural Transformations in Isolated Mitochondria 221 Lloyd Schick and Larry G. Butler Inorganic Pyrophosphatase of Rat Liver Mitochondria . . . . . . . . . . . . . . 235 A. Lasansky and M. G. F. Fuortes The Site of Origin of Electrical Responses in Visual Cells of the Leech, Hirudo Medicinalis . . . . . . . . . . . 241 Sidney Goldfischer and Jay Bernstein Lipofuscin (Aging) Pigment Granules of the Newborn Human Liver . . . . . . . . 253 Richard Holmes and Judy Helms and Gretchen Mercer Cholesterol Requirement of Primary Diploid Human Fibroblasts . . . . . . . 262 Ming C. Liau and Robert P. Perry Ribosome Precursor Particles in Nucleoli 272 Allen L. Bell and David B. Peakall Changes in Fine Structure During Silk Protein Production in the Ampullate Gland of the Spider \bionameAraneus Sericatus . . . . . . . . . . . . . . . 284 D. W. Deamer and R. J. Baskin Ultrastructure of Sarcoplasmic Reticulum Preparations . . . . . . . . . . . . . . 296 M. D. Enger and R. A. Tobey RNA Synthesis in Chinese Hamster Cells 308 G. R. Millward Cellulose contamination: a possible source of error in the interpretation of previous experimental evidence for the $ \alpha $-keratin protofibril . . . . . . 317 Robert S. Gardner The Use of Tricine Buffer in Animal Tissue Cultures . . . . . . . . . . . . 320 D. G. Rayns and F. O. Simpson and Janet M. Ledingham Ultrastructure of Desmosomes in Mammalian Intercalated Disc; Appearances After Lanthanum Treatment . . . . . . . 322 Werner W. Franke and Werner Schinko Nuclear Shape in Muscle Cells . . . . . 326 Walter Rubin Enzyme Cytochemistry of Gastric Parietal Cells at a Fine Structure Level . . . . 332 Bernard Tandler and Leonard L. Ross Observations of Nerve Terminals in Human Labial Salivary Glands . . . . . . . . . 339
J. P. Kraehenbuhl and M. A. Campiche Early Stages of Intestinal Absorption of Specific Antibodies in the Newborn . . . 345 M. M. Elkind and E. Kano and H. Sutton-Gilbert Cell Killing by Actinomycin D in Relation to the Growth Cycle of Chinese Hamster Cells . . . . . . . . . . . . . 366 G. M. Kellerman and D. R. Biggs and Anthony W. Linnane Biogenesis of Mitochondria . . . . . . . 377 Richard W. Young and Dean Bok Participation of the Retinal Pigment Epithelium in the Rod Outer Segment Renewal Process . . . . . . . . . . . . 392 Robert K. Trench and Richard W. Greene and Barbara G. Bystrom Chloroplasts As Functional Organelles in Animal Tissues . . . . . . . . . . . . . 404 Romaine R. Bruns A Symmetrical, Extracellular Fibril . . 418 Thomas L. Lentz Development of the Neuromuscular Junction . . . . . . . . . . . . . . . . 431 Cecilia Bibbiani and Roberto Tongiani and Maria Pia Viola-Magni I. Quantitative Determination of the Amount of DNA Per Nucleus by Interference Microscopy . . . . . . . . 444 Roberto Tongiani and Maria Pia Viola-Magni Ii. Differences in Adrenal Medulla Nuclear DNA Content Among Rats of Different Strains Following Intermittent Exposure to Cold . . . . . . . . . . . . 452 S. R. Pelc and Maria Pia Viola-Magni III. Decrease of Labeled DNA in Cells of the Adrenal Medulla After Intermittent Exposure to Cold . . . . . . . . . . . . 460 Agnes Horvat and Jane Baxandall and Oscar Touster The Isolation of Lysosomes from Ehrlich Ascites Tumor Cells Following Pretreatment of Mice with Triton Wr-1339 469 M. A. Venkatachalam and H. Dariush Fahimi The Use of Beef Liver Catalase As a Protein Tracer for Electron Microscopy 480 William O. Whetsell and Richard P. Bunge Reversible Alterations in the Golgi Complex of Cultured Neurons Treated with an Inhibitor of Active Na and K Transport . . . . . . . . . . . . . . . 490 Margaret E. Beard and Alex B. Novikoff Distribution of Peroxisomes (Microbodies) in the Nephron of the Rat 501 Ulrich Scheer and Werner W. Franke Negative Staining and Adenosine Triphosphatase Activity of Annulate Lamellae of Newt Oocytes . . . . . . . . 519 Jack Rosenbluth Sarcoplasmic Reticulum of an Unusually Fast-Acting Crustacean Muscle . . . . . 534 Martin Mendelson Electrical and Mechanical Characteristics of a Very Fast Lobster Muscle . . . . . . . . . . . . . . . . . 548 E. L. Carstensen and A. Coopersmith and M. Ingram and S. Z. Child Stability of Erythrocytes Fixed in Osmium Tetroxide Solutions . . . . . . . 565 Georgiana M. Jagiello Meiosis and Inhibition of Ovulation in Mouse Eggs Treated with Actinomycin D 571 Toby C. Rodman Morphology and Replication of Intranucleolar DNA in Polytene Nuclei 575 Heinz Falk Rough Thylakoids: Polysomes Attached to Chloroplast Membranes . . . . . . . . . 582 Janardan Reddy and Sukhum Bunyaratvej and Donald Svoboda Microbodies in Experimentally Altered Cells . . . . . . . . . . . . . . . . . 587 Stephen E. Malawista and Hidemi Sato Vinblastine Produces Uniaxial, Birefringent Crystals in Starfish Oocytes . . . . . . . . . . . . . . . . 596 Joel B. Kirkpatrick Stability of Brain Microtubules in Homogenates . . . . . . . . . . . . . . 600 Imogene Schneider Establishment of Three Diploid Cell Lines of Anopheles Stephensi (Diptera: Culicidae) . . . . . . . . . . . . . . . 603 Paul Urban The Fine Structure of Pronuclear Fusion in the Coenocytic Marine Alga Bryopsis Hypnoides Lamouroux . . . . . . . . . . 606
Walther Stoeckenius and Donald M. Engelman Current Models for the Structure of Biological Membranes . . . . . . . . . . 613 Guido Majno and Stephen M. Shea and Monika Leventhal Endothelial Contraction Induced by Histamine-Type Mediators . . . . . . . . 647 Martin A. Gorovsky and John Woodard Studies on Nuclear Structure and Function in \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 673 Robert E. Kelly and Robert V. Rice Ultrastructural Studies on the Contractile Mechanism of Smooth Muscle 683 S. L. Howell and M. Kostianovsky and P. E. Lacy Beta Granule Formation in Isolated Islets of Langerhans . . . . . . . . . . 695 Francesco Clementi and George E. Palade Intestinal Capillaries . . . . . . . . . 706 Richard W. Hendler and Amelia H. Burgess and Raymond Scharff Respiration and Protein Synthesis in \bionameEscherichia coli Membrane-Envelope Fragments . . . . . . 715 N. Nanninga Preservation of the Ultrastructure of Bacillus Subtilis by Chemical Fixation As Verified by Freeze-Etching . . . . . 733 Ronald M. Humphrey and B. R. Brinkley Ultrastructural Studies of Radiation-Induced Chromosome Damage . . 745 Cesar M. Libanati and Carlos J. Tandler The Distribution of the Water-Soluble Inorganic Orthophosphate Ions Within the Cell: Accumulation in the Nucleus . . . 754 Peter G. W. Plagemann Choline Metabolism and Membrane Formation in Rat Hepatoma Cells Grown in Suspension Culture . . . . . . . . . . . 766 Ken Shortman and Kathrin Seligman The Separation of Different Cell Classes from Lymphoid Organs . . . . . . . . . . 783 I-Li Chen and Robert D. Yates Electron Microscopic Radioautographic Studies of the Carotid Body Following Injections of Labeled Biogenic Amine Precursors . . . . . . . . . . . . . . . 794 I-Li Chen and Robert D. Yates and Donald Duncan The Effects of Reserpine and Hypoxia on the Amine-Storing Granules of the Hamster Carotid Body . . . . . . . . . . 804 Jack Rosenbluth Ultrastructure of Dyads in Muscle Fibers of Ascaris Lumbricoides . . . . . . . . 817 B. R. Brinkley and Ronald M. Humphrey Evidence for Subchromatid Organization in Marsupial Chromosomes . . . . . . . . 827 E. C. Raff and J. J. Blum Some Properties of a Model Assay for Ciliary Contractility . . . . . . . . . 831 Leonard Amaral and Louis G. Moriber and Marion Himes The Effect of Cortisone on the Volume and Total Protein Content of Mouse Liver Nuclei . . . . . . . . . . . . . . . . . 835 G. E. Stone Change in Histone\slash DNA Ratio During Population Growth in \bionameTetrahymena 837 Carl M. Feldherr A Comparative Study of Nucleocytoplasmic Interactions . . . . . . . . . . . . . . 841 M. M. Thaler and M. C. L. Cox and C. A. Villee Isolation of Nuclei from Sea Urchin Eggs and Embryos . . . . . . . . . . . . . . 846 Daniel M. Berkowitz and Tsuyoshi Kakefuda and Michael B. Sporn A Simple and Rapid Method for the Isolation of Enzymatically Active HeLa Cell Nuclei . . . . . . . . . . . . . . 851 Guillermo Jaim-Etcheverry and Luis Maria Zieher Selective Demonstration of a Type of Synaptic Vesicle by Phosphotungstic Acid Staining . . . . . . . . . . . . . . . . 855
Y. Marikovsky and D. Danon Electron Microscope Analysis of Young and Old Red Blood Cells Stained with Colloidal Iron for Surface Charge Evaluation . . . . . . . . . . . . . . . 1 E. Skutelsky and D. Danon Reduction in Surface Charge As an Explanation of the Recognition by Macrophages of Nuclei Expelled from Normoblasts . . . . . . . . . . . . . . 8 C. J. Arntzen and R. A. Dilley and F. L. Crane A Comparison of Chloroplast Membrane Surfaces Visualized by Freeze-Etch and Negative Staining Techniques; and Ultrastructural Characterization of Membrane Fractions Obtained from Digitonin-Treated Spinach Chloroplasts 16 S. I. Rubinow A Simple Model of a Steady State Differentiating Cell System . . . . . . 32 R. Bruce Nicklas and Carol A. Koch Chromosome Micromanipulation . . . . . . 40 R. S. Dwivedi and S. K. Dutta and D. P. Bloch Isolation and Characterization of Chromatin from Neurospora Crassa . . . . 51 Becca Fleischer and Sidney Fleischer and Hidehiro Ozawa Isolation and Characterization of Golgi Membranes from Bovine Liver . . . . . . 59 Gustav Niebauer and Walter S. Krawczyk and Richard L. Kidd and George F. Wilgram Osmium Zinc Iodide Reactive Sites in the Epidermal Langerhans Cell . . . . . . . 80 Mary G. Wetzel and Edward D. Korn Phagocytosis of Latex Beads by \bionameAcanthamoeba Castellanii (Neff) 90 Andrew G. Ulsamer and Frank Rees Smith and Edward D. Korn Lipids of \bionameAcanthamoeba Castellanii . . . . . . . . . . . . . . 105 William L. Robison and David Davis Determination of Iodine Concentration and Distribution in Rat Thyroid Follicles by Electron-Probe Microanalysis . . . . . . . . . . . . . 115 Takami Oka and Robert T. Schimke Interaction of Estrogen and Progesterone in Chick Oviduct Development . . . . . . 123 Alexandra von der Decke Activation in Vitro of Rat Liver Polyribosomes . . . . . . . . . . . . . 138 Lewis G. Tilney and Breck Byers Studies on the Microtubules in Heliozoa 148 Heinz Falk Fusiform Vesicles in Plant Cells . . . . 167 Caroline H. Damsky and William M. Nelson and Albert Claude Mitochondria in Anaerobically-Grown, Lipid-Limited Brewer's Yeast . . . . . . 174 Albert W. Sedar Uptake of Peroxidase into the Smooth-Surfaced Tubular System of the Gastric Acid-Secreting Cell . . . . . . 179 Philip B. Dunham and Larry C. Stoner Indentation of the Pellicle of \bionameTetrahymena at the Contractile Vacuole Pore Before Systole . . . . . . 184 D. Thines-Sempoux and A. Amar-Costesec and H. Beaufay and J. Berthet The Association of Cholesterol, 5'-Nucleotidase, and Alkaline Phosphodiesterase I with a Distinct Group of Microsomal Particles . . . . . 189 James L. S. Cobb Modified Cilia in the Gut of the Lamellibranch Mollusc Tapes Watlingi . . 192
J. Morris Johnson A Study of Nucleolar Vacuoles in Cultured Tobacco Cells Using Radioautography, Actinomycin D, and Electron Microscopy . . . . . . . . . . 197 Robert R. Klevecz Temporal Order in Mammalian Cells . . . 207 Harriet M. McCurdy Enzyme Localization During Melanogenesis 220 Edmund Guttes and Sophie Guttes Replication of Nucleolus-Associated DNA During ``G$_2$ Phase'' in \bionamePhysarum Polycephalum . . . . . 229 Charles A. Ashley and Theodore Peters Electron Microscopic Radioautographic Detection of Sites of Protein Synthesis and Migration in Liver . . . . . . . . . 237 Charles J. Flickinger The Development of Golgi Complexes and Their Dependence Upon the Nucleus in Amebae . . . . . . . . . . . . . . . . . 250 Selma Silagi Control of Pigment Production in Mouse Melanoma Cells in Vitro . . . . . . . . 263 H. Dariush Fahimi Cytochemical Localization of Peroxidatic Activity of Catalase in Rat Hepatic Microbodies (Peroxisomes) . . . . . . . 275 P. Whur and Annette Herscovics and C. P. Leblond Radioautographic Visualization of the Incorporation of Galactose-$^3$H and Mannose-$^3$H by Rat Thyroids in Vitro in Relation to the Stages of Thyroglobulin Synthesis . . . . . . . . 289 Harunori Ishikawa and Richard Bischoff and Howard Holtzer Formation of Arrowhead Complexes with Heavy Meromyosin in a Variety of Cell Types . . . . . . . . . . . . . . . . . 312 Emile Vivier and André Petitprez Le Complexe Membranaire Superficiel Et Son Evolution Lors De L'Elaboration Des Individus-Fils Chez Toxoplasma Gondii 329 Sue Ellen Frederick and Eldon H. Newcomb Cytochemical Localization of Catalase in Leaf Microbodies (Peroxisomes) . . . . . 343 Jerome J. Wolken Microspectrophotometry and the Photoreceptor of \bionamePhycomyces I 354 K. P. Dingemans The Relation Between Cilia and Mitoses in the Mouse Adenohypophysis . . . . . . 361 Peter G. Canonico and John W. C. Bird The Use of Acridine Orange As a Lysosomal Marker in Rat Skeletal Muscle 367 Elliott Robbins and Michael Shelanski Synthesis of a Colchicine-Binding Protein During the HeLa Cell Life Cycle 371 A. Macieira-Coelho and J. Ponten Analogy in Growth Between Late Passage Human Embryonic and Early Passage Human Adult Fibroblasts . . . . . . . . . . . 374 Lennart Boquist Intranuclear rods in pancreatic islet $ \beta $-cells . . . . . . . . . . . . . 377 Yutaka Shimada and D. A. Fischman and A. A. Moscona The Development of Nerve-Muscle Junctions in Monolayer Cultures of Embryonic Spinal Cord and Skeletal Muscle Cells . . . . . . . . . . . . . . 382
Arne Lòvlie Increase in Function During Growth of a Single Cell Organelle . . . . . . . . . 389 H. J. Stoltze and N. S. T. Lui and O. R. Anderson and O. A. Roels The Influence of the Mode of Nutrition on the Digestive System of Ochromonas Malhamensis . . . . . . . . . . . . . . 396 Olga Stein and Yechezkiel Stein and Dewitt S. Goodman and Noel H. Fidge The Metabolism of Chylomicron Cholesteryl Ester in Rat Liver . . . . . 410 Frank C. Bancroft and Lawrence Levine and Armen H. Tashjian Control of Growth Hormone Production by a Clonal Strain of Rat Pituitary Cells 432 Jacob E. Berger Optical Diffraction Studies of Crystalline Structures in Electron Micrographs . . . . . . . . . . . . . . 442 Irmin Sternlieb and Jacob E. Berger Optical Diffraction Studies of Crystalline Structures in Electron Micrographs . . . . . . . . . . . . . . 448 J. Metuzals and C. S. Izzard Spatial Patterns of Threadlike Elements in the Axoplasm of the Giant Nerve Fiber of the Squid (\bionameLoligo Pealii L.) As Disclosed by Differential Interference Microscopy and by Electron Microscopy . . . . . . . . . . . . . . . 456 J. Metuzals Configuration of a Filamentous Network in the Axoplasm of the Squid (\bionameLoligo Pealii L.) Giant Nerve Fiber . . . . . . . . . . . . . . . . . 480 M. N. Berry and D. S. Friend High-Yield Preparation of Isolated Rat Liver Parenchymal Cells . . . . . . . . 506 Clinton D. Stoner and Howard D. Sirak Osmotically-Induced Alterations in Volume and Ultrastructure of Mitochondria Isolated from Rat Liver and Bovine Heart . . . . . . . . . . . . . . 521 Katsuhide Nishi and Chikayoshi Oura and Wazir Pallie Fine Structure of Pacinian Corpuscles in the Mesentery of the Cat . . . . . . . . 539 Awtar Krishan and Dora Hsu Observations on the Association of Helical Polyribosomes and Filaments with Vincristine-Induced Crystals in Earle's L-Cell Fibroblasts . . . . . . . . . . . 553 Allen Costoff and W. H. McShan Isolation and Biological Properties of Secretory Granules from Rat Anterior Pituitary Glands . . . . . . . . . . . . 564 Susan G. Langreth Spermiogenesis in Cancer Crabs . . . . . 575 Francis J. Manasek The Appearance of Granules in the Golgi Complex of Embryonic Cardiac Myocytes 605 R. J. Baskin and D. W. Deamer Comparative Ultrastructure and Calcium Transport in Heart and Skeletal Muscle Microsomes . . . . . . . . . . . . . . . 610 Awtar Krishan and Ratna Ray-Chaudhuri Asynchrony of Nuclear Development in Cytochalasin-Induced Multinucleate Cells 618 M. W. Berns and R. S. Olson and D. E. Rounds Argon Laser Micro-Irradiation of Nucleoli . . . . . . . . . . . . . . . . 621 Andrea Mastro and Emma Shelton and W. C. Hymer DNA Synthesis in the Rat Anterior Pituitary . . . . . . . . . . . . . . . 626 Elliott Robbins and Gene A. Morrill Oxygen Uptake During the HeLa Cell Life Cycle and Its Correlation with Macromolecular Synthesis . . . . . . . . 629