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Volume 44, Number 1, January, 1970W. G. Forssmann and L. Girardier A Study of the T System in Rat Heart . . 1 Paul Personne and Winston Anderson Localisation Mitochondriale D'Enzymes Liees Au Metabolisme Du Glycogene Dans Le Spermatozoide De L'Escargot . . . . . 20 Winston A. Anderson and Paul Personne The Localization of Glycogen in the Spermatozoa of Various Invertebrate and Vertebrate Species . . . . . . . . . . . 29 Bernard J. Panner and Carl R. Honig Locus and State of Aggregation of Myosin in Tissue Sections of Vertebrate Smooth Muscle . . . . . . . . . . . . . . . . . 52 Virginia M. Tennyson The Fine Structure of the Axon and Growth Cone of the Dorsal Root Neuroblast of the Rabbit Embryo . . . . 62 T. W. Keenan and D. James Morré and Diane E. Olson and W. N. Yunghans and Stuart Patton Biochemical and Morphological Comparison of Plasma Membrane and Milk Fat Globule Membrane from Bovine Mammary Gland . . . 80 B. P. Gerhardt and Harry Beevers Developmental Studies on Glyoxysomes in Ricinus Endosperm . . . . . . . . . . . 94 Stephen R. Gross and Lewis Aronow and William B. Pratt The Outward Transport of Cortisol by Mammalian Cells in Vitro . . . . . . . . 103 David Bodian An Electron Microscopic Characterization of Classes of Synaptic Vesicles by Means of Controlled Aldehyde Fixation . . . . 115 Camillo Peracchia A System of Parallel Septa in Crayfish Nerve Fibers . . . . . . . . . . . . . . 125 Richard Bischoff and Howard Holtzer Inhibition of Myoblast Fusion After One Round of DNA Synthesis in $5$-Bromodeoxyuridine . . . . . . . . . 134 Mary A. Bonneville and Melvyn Weinstock Brush Border Development in the Intestinal Absorptive Cells of \bionameXenopus During Metamorphosis . . 151 Edmund B. Masurovsky and Helena H. Benitez and Seung U. Kim and Margaret R. Murray Origin, Development, and Nature of Intranuclear Rodlets and Associated Bodies in Chicken Sympathetic Neurons 172 Daniel Szollosi Cortical Cytoplasmic Filaments of Cleaving Eggs: a Structural Element Corresponding to the Contractile Ring 192 William H. J. Douglas and Robert C. Ripley and Richard A. Ellis Enzymatic Digestion of Desmosome and Hemidesmosome Plaques Performed on Ultrathin Sections . . . . . . . . . . . 211 Yasuo Uehara and Geoffrey Burnstock Demonstration of ``Gap Junctions'' Between Smooth Muscle Cells . . . . . . 215 Sherman Bloom Structural Changes in Nuclear Envelopes During Elongation of Heart Muscle Cells 218 A. Sengel and P. Stoebner Golgi Origin of Tubular Inclusions in Endothelial Cells . . . . . . . . . . . 223 Janardan Reddy and Masahiro Chiga and Sukhum Bunyaratvej and Donald Svoboda Microbodies in Experimentally Altered Cells . . . . . . . . . . . . . . . . . 226 Robert Marantz and Michael L. Shelanski Structure of Microtubular Crystals Induced by Vinblastine in Vitro . . . . 234
David M. Phillips Insect Sperm: Their Structure and Morphogenesis . . . . . . . . . . . . . 243 W. H. Butler and J. D. Judah Preparation of Isolated Rat Liver Mitochondria for Electron Microscopy . . 278 K. W. Henningsen and J. E. Boynton Macromolecular Physiology of Plastids 290 I. W. Craig and A. Gibor A Direct Light Effect on Maintaining Photosynthetic Activity of Nitella Chloroplasts . . . . . . . . . . . . . . 305 Elinor S. Mills and Yale J. Topper Some Ultrastructural Effects of Insulin, Hydrocortisone, and Prolactin on Mammary Gland Explants . . . . . . . . . . . . . 310 K. E. Kuettner and L. W. Soble and R. D. Ray and R. L. Croxen and M. Passovoy and R. Eisenstein Lysozyme in Epiphyseal Cartilage . . . . 329 Arthur R. Hand The Fine Structure of Von Ebner's Gland of the Rat . . . . . . . . . . . . . . . 340 Joseph B. Warshaw and Mary L. Terry Cellular Energy Metabolism During Fetal Development . . . . . . . . . . . . . . 354 Christopher L. F. Woodcock and Lawrence Bogorad Evidence for Variation in the Quantity of DNA Among Plastids of Acetabularia 361 Richard W. Hendler and Amelia H. Burgess and Raymond Scharff Respiration and Protein Synthesis in \bionameEscherichia coli Membrane-Envelope Fragments . . . . . . 376 Laurent Descarries and Bernard Droz Intraneural Distribution of Exogenous Norepinephrine in the Central Nervous System of the Rat . . . . . . . . . . . 385 Elliott Robbins and Thoru Pederson and Paul Klein Comparison of Mitotic Phenomena and Effects Induced by Hypertonic Solutions in HeLa Cells . . . . . . . . . . . . . 400 Daniel W. McKeel and Leonard Jarett Preparation and Characterization of a Plasma Membrane Fraction from Isolated Fat Cells . . . . . . . . . . . . . . . 417 Ray F. Everet and Bharati P. Deshpande Nuclear P Protein in Sieve Elements of \bionameTilia Americana . . . . . . . . 462 Talat A. Khan and Jane Overton Lanthanum Staining of Developing Chick Cartilage and Reaggregating Cartilage Cells . . . . . . . . . . . . . . . . . 433 Eric Holtzman and Alan R. Freeman and Leonard A. Kashner A Cytochemical and Electron Microscope Study of Channels in the Schwann Cells Surrounding Lobster Giant Axons . . . . 438 Wolf H. Fahrenbach The Cyanoblast: Hemocyanin Formation in Limulus Polyphemus . . . . . . . . . . . 445 John W. Moser and Gerald L. Kreitner Centrosome Structure in Anthoceros Laevis and Marchantia Polymorpha . . . . 454 F. P. Moss and C. P. Leblond Nature of Dividing Nuclei in Skeletal Muscle of Growing Rats . . . . . . . . . 459
Ruy Soeiro and James E. Darnell A Comparison Between Heterogeneous Nuclear RNA and Polysomal Messenger RNA in HeLa Cells by RNA-DNA Hybridization 467 Gerassimos N. Pagoulatos and James E. Darnell A Comparison of the Heterogeneous Nuclear RNA of HeLa Cells in Different Periods of the Cell Growth Cycle . . . . 476 D. James Morré and R. L. Hamilton and H. H. Mollenhauer and R. W. Mahley and W. P. Cunningham and R. D. Cheetham and V. S. Lequire Isolation of a Golgi Apparatus-Rich Fraction from Rat Liver . . . . . . . . 484 R. D. Cheetham and D. James Morré and Wayne N. Yunghans Isolation of a Golgi Apparatus-Rich Fraction from Rat Liver . . . . . . . . 492 Robert M. Lavker and A. Gedeon Matoltsy Formation of Horny Cells . . . . . . . . 501 Sidney Goldfischer and Alex B. Novikoff and Arline Albala and Luis Biempica Hemoglobin Uptake by Rat Hepatocytes and Its Breakdown Within Lysosomes . . . . . 513 R. K. Togasaki and R. P. Levine Chloroplast structure and function in \bionameac-20, a mutant strain of \bionameChlamydomonas reinhardi . . . . 531 R. P. Levine and A. Paszewski Chloroplast structure and function in \bionameac-20, a mutant strain of \bionameChlamydomonas reinhardi . . . . 540 Ursula W. Goodenough and R. P. Levine Chloroplast structure and function in \bionameac-20, a mutant strain of \bionameChlamydomonas reinhardi . . . . 547 I. Goldberg and I. Ohad Biogenesis of Chloroplast Membranes . . 563 I. Goldberg and I. Ohad Biogenesis of Chloroplast Membranes . . 572 M. V. L. Bennett and J. P. Trinkaus Electrical Coupling Between Embryonic Cells by Way of Extracellular Space and Specialized Junctions . . . . . . . . . 592 R. E. Stephens and R. E. Kane Some Properties of Hyalin . . . . . . . 611 Benita De Petrocellis and Philip Siekevitz and George E. Palade Changes in chemical composition of thylakoid membranes during greening of the \bionamey-1 mutant of \bionameChlamydomonas reinhardi . . . . 618 Joseph Bryan The Isolation of a Major Structural Element of the Sea Urchin Fertilization Membrane . . . . . . . . . . . . . . . . 635 Russell Ross and Newton B. Everett and Ruth Tyler Wound Healing and Collagen Formation . . 645 Judy M. Strum and Morris J. Karnovsky Cytochemical Localization of Endogenous Peroxidase in Thyroid Follicular Cells 655 J. Stuve and P. Galle Role of Mitochondria in the Handling of Gold by the Kidney . . . . . . . . . . . 667 H. Hartman and R. M. Dowben Polyribosomes from \bionameTetrahymena 676 H. Firket and A. F. Hopper Abnormal Cycle Phase Durations in Polyploid Cells Or Cells with Irregular Mitosis in a HeLa Cell Population . . . 678 Baccio Baccetti and Romano Dallai and Floriana Rosati The Spermatozoon of Arthropoda . . . . . 681 Martin Hagopian and David Spiro Derivation of the Z Line in the Embryonic Chick Heart . . . . . . . . . 683 Richard R. Lynn and Paul T. Magee Development of the Spore Wall During Ascospore Formation in \bionameSaccharomyces Cerevisiae . . . . 688 Paul R. Burton Optical Diffraction and Translational Reinforcement of Microtubules Having a Prominent Helical Wall Structure . . . . 693 R. J. Podolsky and T. Hall and S. L. Hatchett Identification of Oxalate Precipitates in Striated Muscle Fibers . . . . . . . 699
Emma Shelton and Edward L. Kuff and Elizabeth S. Maxwell and J. T. Harrington Cytoplasmic Particles and Aminoacyl Transferase I Activity . . . . . . . . . 1 J. J. Mire and W. J. Hendelman and R. P. Bunge Observations on a Transient Phase of Focal Swelling in Degenerating Unmyelinated Nerve Fibers . . . . . . . 9 H. Bruce Bosmann and R. Alan Winston Synthesis of Glycoprotein, Glycolipid, Protein, and Lipid in Synchronized L5178Y Cells . . . . . . . . . . . . . . 23 Robert L. Trelstad The Golgi Apparatus in Chick Corneal Epithelium: Changes in Intracellular Position During Development . . . . . . 34 A. J. Solari and Laura L. Tres The Three-Dimensional Reconstruction of the XY Chromosomal Pair in Human Spermatocytes . . . . . . . . . . . . . 43 Dorothy Ford Bainton and Marilyn G. Farquhar Segregation and Packaging of Granule Enzymes in Eosinophilic Leukocytes . . . 54 Robert J. Klebe and Tchaw-Ren Chen and Frank H. Ruddle Controlled Production of Proliferating Somatic Cell Hybrids . . . . . . . . . . 74 Charles C. Childress and Bertram Sacktor and I. William Grossman and Ernest Bueding Isolation, Ultrastructure, and Biochemical Characterization of Glycogen in Insect Flight Muscle . . . . . . . . 83 Judson D. Sheridan Low-Resistance Junctions Between Cancer Cells in Various Solid Tumors . . . . . 91 Mary A. Grillo Cytoplasmic Inclusions Resembling Nucleoli in Sympathetic Neurons of Adult Rats . . . . . . . . . . . . . . . . . . 100 Peter G. Legg and Richard L. Wood New Observations on Microbodies . . . . 118 G. Blobel and D. D. Sabatini Controlled Proteolysis of Nascent Polypeptides in Rat Liver Cell Fractions 130 D. D. Sabatini and G. Blobel Controlled Proteolysis of Nascent Polypeptides in Rat Liver Cell Fractions 146 Bong Yul Yoo Ultrastructural Changes in Cells of Pea Embryo Radicles During Germination . . . 158 Wiktor Djaczenko and Arrigo Benedetto and Renato Pezzi Formation of Helical Polyribosomes in Poliovirus-Infected Cells of the 37 Rc Line . . . . . . . . . . . . . . . . . . 173 Sibdas Ghosh and Renate Lettré and Ira Ghosh DNA Synthetic Pattern in the Nucleolus 177 Sibdas Ghosh and Ira Ghosh DNA Synthetic Pattern in the Nucleolus 181 Thoru Pederson and Seymour Gelfant Macromolecular Synthesis in Dogfish Peripheral Blood Cells . . . . . . . . . 183 Filiberto Giacomelli and Joseph Wiener and David Spiro Cross-Striated Arrays of Filaments in Endothelium . . . . . . . . . . . . . . 188 Jacob Dyckman and Joel K. Weltman A Morphological Analysis of Binding of a Hydrophobic Probe to Cells . . . . . . . 192 R. G. Herrmann and K. V. Kowallik Selective Presentation of DNA-Regions and Membranes in Chloroplasts and Mitochondria . . . . . . . . . . . . . . 198
Wincenty Kilarski and Andrzej Jasi\'nski The Formation of Multivesicular Bodies from the Nuclear Envelope . . . . . . . 205 Fredrick J. Seil and Robert M. Herndon Cerebellar Granule Cells in Vitro . . . 212 Anders Hamberger and Christian Blomstrand and Albert L. Lehninger Comparative Studies on Mitochondria Isolated from Neuron-Enriched and Glia-Enriched Fractions of Rabbit and Beef Brain . . . . . . . . . . . . . . . 221 Edith K. MacRae and Gerald D. Meetz Electron Microscopy of the Ammoniacal Silver Reaction for Histones in the Erythropoietic Cells of the Chick . . . 235 R. Malcolm Brown and Werner W. Franke and Hans Kleinig and Heinz Falk and Peter Sitte Scale Formation in Chrysophycean Algae 246 Daniel A. Goodenough and Jean Paul Revel A Fine Structural Analysis of Intercellular Junctions in the Mouse Liver . . . . . . . . . . . . . . . . . 272 T. L. Chan and John W. Greenawalt and Peter L. Pedersen Biochemical and Ultrastructural Properties of a Mitochondrial Inner Membrane Fraction Deficient in Outer Membrane and Matrix Activities . . . . . 291 Anthony P. Mahowald and Joan M. Strassheim Intercellular Migration of Centrioles in the Germarium of \bionameDrosophila Melanogaster . . . . . . . . . . . . . . 306 Peter G. Canonico and John W. C. Bird Lysosomes in Skeletal Muscle Tissue . . 321 Jerome J. Freed and Marcia M. Lebowitz The Association of a Class of Saltatory Movements with Microtubules in Cultured Cells . . . . . . . . . . . . . . . . . 334 Carlos J. Tandler and César M. Libanati and Carlos A. Sanchis The Intracellular Localization of Inorganic Cations with Potassium Pyroantimonate . . . . . . . . . . . . . 355 Robert M. Rosenbaum and Murray Wittner Ultrastructure of Bacterized and Axenic Trophozoites of Entamoeba Histolytica with Particular Reference to Helical Bodies . . . . . . . . . . . . . . . . . 367 Barry A. Palevitz and Eldon H. Newcomb A Study of Sieve Element Starch Using Sequential Enzymatic Digestion and Electron Microscopy . . . . . . . . . . 383 S. M. Cocucci and M. Sussman RNA in Cytoplasmic and Nuclear Fractions of Cellular Slime Mold Amebas . . . . . 399 Brian Poole and Tokuhiko Higashi and Christian de Duve The Synthesis and Turnover of Rat Liver Peroxisomes . . . . . . . . . . . . . . 408 Jerome S. Kaye The Fine Structure and Arrangement of Microcylinders in the Lumina of Flagellar Fibers in Cricket Spermatids 416 D. Zirwer and E. Buder and W. Schälike and R. Wetzel Lineardichroitische Untersuchungen zur DNS-Organisation in Spermienköpfen von \bionameLocusta Migratoria L. (German) [Linear dichroitics on DNA organization in sperm heads of \bionameLocusta Migratoria L] . . . . . . . . . . . . . 431 Allen L. Horwitz and Albert Dorfman The Growth of Cartilage Cells in Soft Agar and Liquid Suspension . . . . . . . 434 Peter K. Hepler and J. Richard McIntosh and Story Cleland Intermicrotubule Bridges in Mitotic Spindle Apparatus . . . . . . . . . . . 438 Ulrich Scheer The Ultrastructure of the Nuclear Envelope of Amphibian Oocytes: a Reinvestigation . . . . . . . . . . . . 445 Steven C. Mohos and Lorant Skoza Variations in the Sialic Acid Concentration of Glomerular Basement Membrane Preparations Obtained by Ultrasonic Treatment . . . . . . . . . . 450 Milton J. Finegold and Laura E. Greene Mitochondrial Damage in Experimental Congenital Adrenal Hyperplasia . . . . . 455 Dougald G. Scott and Charles W. Daniel Filaments in the Division Furrow of Mouse Mammary Cells . . . . . . . . . . 461 J. Norman Grim Ultrastructure of Ciliary Microtubules After Critical Point Drying . . . . . . 466 John Aronson and Shinya Inoué Reversal by Light of the Action of N-Methyl N-Desacetyl Colchicine on Mitosis . . . . . . . . . . . . . . . . 470
L. Recher and J. Whitescarver and L. Briggs A Cytochemical and Radioautographic Study of Human Tissue Culture Cell Nucleoli . . . . . . . . . . . . . . . . 479 George Weinbaum and Donald A. Fischman and Shinichi Okuda Membrane Modifications in Nutritionally Induced Filamentous \bionameEscherichia coli B . . . . . . . . . . . . . . . . . 493 Thoru Pederson and Elliott Robbins Absence of Translational Control of Histone Synthesis During the HeLa Cell Life Cycle . . . . . . . . . . . . . . . 509 David E. F. Harrison Undamped Oscillations of Pyridine Nucleotide and Oxygen Tension in Chemostat Cultures of Klebsiella Aerogenes . . . . . . . . . . . . . . . 514 Robert J. Mclean and George F. Pessoney A Large Scale Quasi-Crystalline Lamellar Lattice in Chloroplasts of the Green Alga Zygnema . . . . . . . . . . . . . . 522 Lennart Boquist Cilia and Vesicular Particles in the Endocrine Pancreas of the Mongolian Gerbil . . . . . . . . . . . . . . . . . 532 R. M. Hicks and B. Ketterer Isolation of the Plasma Membrane of the Luminal Surface of Rat Bladder Epithelium, and the Occurrence of a Hexagonal Lattice of Subunits Both in Negatively Stained Whole Mounts and in Sectioned Membranes . . . . . . . . . . 542 Nessly C. Craig and Robert P. Perry Aberrant Intranucleolar Maturation of Ribosomal Precursors in the Absence of Protein Synthesis . . . . . . . . . . . 554 Nicholas C. Spitzer Low Resistance Connections Between Cells in the Developing Anther of the Lily . . 565 Richard L. Wood and Peter G. Legg Peroxidase Activity in Rat Liver Microbodies After Amino-Triazole Inhibition . . . . . . . . . . . . . . . 576 Marco Baggiolini and James G. Hirsch and Christian de Duve Further Biochemical and Morphological Studies of Granule Fractions from Rabbit Heterophil Leukocytes . . . . . . . . . 586 Pedro Pinto da Silva and Daniel Branton Membrane Splitting in Freeze-Etching . . 598 Joseph Bryan On the Reconstitution of the Crystalline Components of the Sea Urchin Fertilization Membrane . . . . . . . . . 606 R. E. Kane Direct Isolation of the Hyaline Layer Protein Released from the Cortical Granules of the Sea Urchin Egg at Fertilization . . . . . . . . . . . . . 615 Ajit Kumar Ribosome Synthesis in \bionameTetrahymena Pyriformis . . . . . 623 Richard Rodewald Selective Antibody Transport in the Proximal Small Intestine of the Neonatal Rat . . . . . . . . . . . . . . . . . . 635 Yoshiyuki Ichikawa and Masao Kuroda and Toshio Yamano Zonation of hemoprotein P-450 and cytochrome $ b_5 $ in the adrenocortex of mammals . . . . . . . . . . . . . . . 640 Sin Hang Lee The Possible Role of the Vesicles in Renal Ammonia Excretion . . . . . . . . 644 Thomas W. Tillack and Vincent T. Marchesi Demonstration of the Outer Surface of Freeze-Etched Red Blood Cell Membranes 649 Kiyoshi Hama and Fumio Nagata A Stereoscope Observation of Tracheal Epithelium of Mouse by Means of the High Voltage Electron Microscope . . . . . . 654 B. W. Payton Histological Staining Properties of Procion Yellow M4Rs . . . . . . . . . . 659 Peter Barland and Eleanor A. Schroeder A New Rapid Method for the Isolation of Surface Membranes from Tissue Culture Cells . . . . . . . . . . . . . . . . . 662 Gary Bennett Migration of Glycoprotein from Golgi Apparatus to Cell Coat in the Columnar Cells of the Duodenal Epithelium . . . . 668
Yutaka Tashiro and Eiichi Otsuki Studies on the Posterior Silk Gland of the Silkworm Bombix Mori . . . . . . . . 1 John N. Loeb and Daniel V. Kimberg Sedimentation Properties of Rat Liver Mitochondria . . . . . . . . . . . . . . 17 Helen A. Padykula and Geraldine F. Gauthier The Ultrastructure of the Neuromuscular Junctions of Mammalian Red, White, and Intermediate Skeletal Muscle Fibers . . 27 Isaac Schenkein and Jonathan W. Uhr Immunoglobulin Synthesis and Secretion 42 Daniel Zagury and Jonathan W. Uhr and James D. Jamieson and George E. Palade Immunoglobulin Synthesis and Secretion 52 Virginia M. Tennyson and Miro Brzin The Appearance of Acetylcholinesterase in the Dorsal Root Neuroblast of the Rabbit Embryo . . . . . . . . . . . . . 64 Robert S. Redman and Leo M. Sreebny Proliferative Behavior of Differentiating Cells in the Developing Rat Parotid Gland . . . . . . . . . . . 81 K. Watson and J. M. Haslam and Anthony W. Linnane Biogenesis of Mitochondria . . . . . . . 88 J. M. Hanifin and M. J. Cline Human Monocytes and Macrophages . . . . 97 Peter M. M. Rae The Nature and Processing of Ribosomal Ribonucleic Acid in a Dinoflagellate . . 106 Richard W. Hendler and N. Nanninga Respiration and Protein Synthesis in \bionameEscherichia coli Membrane-Envelope Fragments . . . . . . 114 A. Tixier-Vidal and D. Gourdji Synthesis and Renewal of Proteins in Duck Anterior Hypophysis in Organ Culture . . . . . . . . . . . . . . . . 130 Hans-G. Heidrich and Roland Stahn and Kurt Hannig The Surface Charge of Rat Liver Mitochondria and Their Membranes . . . . 137 R. A. Tobey and K. D. Ley Regulation of Initiation of DNA Synthesis in Chinese Hamster Cells . . . 151 Eiichi Tani and Toshio Ametani Substructure of Microtubules in Brain Nerve Cells As Revealed by Ruthenium Red 159 P. Klein and E. Robbins An Ultrasensitive Assay for Soluble Sulfhydryl and Its Application to the Study of Glutathione Levels During the HeLa Life Cycle . . . . . . . . . . . . 165 M. A. Venkatachalam and M. H. Soltani and H. Dariush Fahimi Fine Structural Localization of Peroxidase Activity in the Epithelium of Large Intestine of Rat . . . . . . . . . 168 John W. Greenawalt and Carl Schnaitman An Appraisal of the Use of Monoamine Oxidase As an Enzyme Marker for the Outer Membrane of Rat Liver Mitochondria 173 James M. Hyde and Dietrich Peters The Influence of pH and Osmolality on Fixation of the Fowlpox Virus Core . . . 179 W. F. Harris The Arrangement of the Axonemal Microtubules and Links of Echinosphaerium Nucleofilum . . . . . . 183 Joseph Tupper and John W. Saunders and Charles Edwards The Onset of Electrical Communication Between Cells in the Developing Starfish Embryo . . . . . . . . . . . . . . . . . 187 Erwin Huebner and Everett Anderson The Effects of Vinblastine Sulfate on the Microtubular Organization of the Ovary of Rhodnius Prolixus . . . . . . . 191
David S. Smith and U. Järlfors and R. Beránek The Organization of Synaptic Axoplasm in the Lamprey (\bionamePetromyzon Marinus) Central Nervous System . . . . . . . . . 199 F. Rudolf Turner The Effects of Colchicine on Spermatogenesis in Nitella . . . . . . . 220 Donald R. DiBona and Mortimer M. Civan The Effect of Smooth Muscle on the Intercellular Spaces in Toad Urinary Bladder . . . . . . . . . . . . . . . . 235 Bland S. Montenecourt and Margaret E. Langsam and Donald T. Dubin Mitochondrial RNA from Cultured Animal Cells . . . . . . . . . . . . . . . . . 245 Daniel S. Friend and Gail E. Brassil Osmium Staining of Endoplasmic Reticulum and Mitochondria in the Rat Adrenal Cortex . . . . . . . . . . . . . . . . . 252 Thomas D. Pollard and Susumu Ito Cytoplasmic Filaments of Amoeba Proteus 267 Z. W. Hall and M. D. Bownds and E. A. Kravitz The Metabolism of Gamma Aminobutyric Acid in the Lobster Nervous System . . . 290 Isabelle R. Faeder and Miriam M. Salpeter Glutamate Uptake by a Stimulated Insect Nerve Muscle Preparation . . . . . . . . 300 Frank J. Longo and Everett Anderson The Effects of Nicotine on Fertilization in the Sea Urchin, \bionameArbacia Punctulata . . . . . . . . . . . . . . . 308 Samuel W. Cushman Structure-Function Relationships in the Adipose Cell . . . . . . . . . . . . . . 326 Samuel W. Cushman Structure-Function Relationships in the Adipose Cell . . . . . . . . . . . . . . 342 Samuel W. Cushman and Martin A. Rizack Structure-Function Relationships in the Adipose Cell . . . . . . . . . . . . . . 354 Geert Ab and Ronald A. Malt Metabolism of Ribosomal Precursor Ribonucleic Acid in Kidney . . . . . . . 362 T. Tidwell The Methylation of Transfer Ribonucleic Acid During Regeneration of the Liver 370 Werner W. Franke and Barbara Deumling and Baerbel Ermen and Ernst-Dieter Jarasch and Hans Kleinig Nuclear Membranes from Mammalian Liver 379 Hans Kleinig Nuclear Membranes from Mammalian Liver 396 Bunsuke Osogoe and Ayako Ueki A Radioautographic Study of the Utilization of Deoxycytidine for the Formation of Deoxyribonucleic Acid-Thymine in Lymphocytes . . . . . . 403 P. L. Senger and R. G. Saacke Unusual Mitochondria of the Bovine Oocyte . . . . . . . . . . . . . . . . . 405 G. Bennett and C. P. Leblond Formation of Cell Coat Material for the Whole Surface of Columnar Cells in the Rat Small Intestine, As Visualized by Radioautography with L-Fucose-$^3$H . . 409 R. E. Stephens and E. E. Levine Some Enzymatic Properties of Axonemes from the Cilia of Pecten Irradians . . . 416 Doreen E. Ashhurst An Insect Desmosome . . . . . . . . . . 421 H. J. Arnott and A. C. G. Best and J. A. C. Nicol Occurrence of Melanosomes and of Crystal Sacs Within the Same Cell in the \bionameTapetum Lucidum of the Stingaree 426 Costante Ceccarini and Maria S. Campo and Franca Andronico Ribosomal Subunit Exchange in \bionameDictyostelium Purpureum . . . . 428 Robert D. Prusch and Philip B. Dunham Contraction of Isolated Contractile Vacuoles from Amoeba Proteus . . . . . . 431
Eugene L. Vigil Cytochemical and Developmental Changes in Microbodies (Glyoxysomes) and Related Organelles of Castor Bean Endosperm . . 435 Kate M. Baldwin The Fine Structure and Electrophysiology of Heart Muscle Cell Injury . . . . . . 455 R. A. Boshes Drosophila Polyribosomes . . . . . . . . 477 John Walberg Anderson and Milton B. Yatvin Metabolic and Ultrastructural Changes in the Frog Ovarian Follicle in Response to Pituitary Stimulation . . . . . . . . . 491 Frank A. Rawlins and Betty G. Uzman Retardation of Peripheral Nerve Myelination in Mice Treated with Inhibitors of Cholesterol Biosynthesis 505 Betrand Bordier and Leonard Ornstein and Richard P. Wedeen The Intrarenal Distribution of Tritiated Para-Aminohippuric Acid Determined by a Modified Technique of Section Freeze-Dry Radioautography . . . . . . . . . . . . 518 William R. Jeffery and Kenneth D. Stuart and Joseph Frankel The Relationship Between Deoxyribonucleic Acid Replication and Cell Division in Heat-Synchronized \bionameTetrahymena . . . . . . . . . . 533 R. D. Yates and I-Li Chen and Donald Duncan Effects of Sinus Nerve Stimulation on Carotid Body Glomus Cells . . . . . . . 544 Lyndell L. Millecchia and Maria A. Rudzinska Basal Body Replication and Ciliogenesis in a Suctorian, \bionameTokophrya Infusionum . . . . . . . . . . . . . . . 553 Lewis G. Tilney and Janette Goddard Nucleating Sites for the Assembly of Cytoplasmic Microtubules in the Ectodermal Cells of Blastulae of \bionameArbacia Punctulata . . . . . . . 564 R. Stahn and K.-P. Maier and K. Hannig A New Method for the Preparation of Rat Liver Lysosomes . . . . . . . . . . . . 576 A. C. Esterhuizen and S. L. Howell Ultrastructure of the A-Cells of Cat Islets of Langerhans Following Sympathetic Stimulation of Glucagon Secretion . . . . . . . . . . . . . . . 593 Sarah P. Gibbs Nuclear and Organelle RNA Synthesis in Ochromonas: the Effects of Light . . . . 599 Gerd G. Maul Ultrastructure of Pore Complexes of Annulate Lamellae . . . . . . . . . . . 604 J. W. I. M. Simons Characterization of Somatic Cells by Determination of Their Volumes with a Coulter Counter . . . . . . . . . . . . 610 William G. Walther and Leland N. Edmunds Periodic Increase in Deoxyribonuclease Activity During the Cell Cycle in Synchronized Euglena . . . . . . . . . . 613 Izhak Nir and Arnold M. Seligman Photooxidation of Diaminobenzidine (Dab) by Chloroplast Lamellae . . . . . . . . 617 Gary E. Wise and Charles J. Flickinger Cytochemical Staining of the Golgi Apparatus in Amoeba Proteus . . . . . . 620 Reuben Eisenstein and Charalampos Arsenis and Klaus E. Kuettner Electron Microscopic Studies of Cartilage Matrix Using Lysozyme As a Vital Stain . . . . . . . . . . . . . . 626
A. Martinez-Palomo and J. Alanis and D. Benitez Transitional Cardiac Cells of the Conductive System of the Dog Heart . . . 1 S. C. Lakhotia and A. S. Mukherjee Chromosomal Basis of Dosage Compensation in \bionameDrosophila . . . . . . . . . 18 Hans Glaumann and Gustav Dallner Subfractionation of Smooth Microsomes from Rat Liver . . . . . . . . . . . . . 34 J. P. Chalcroft and S. Bullivant An Interpretation of Liver Cell Membrane and Junction Structure Based on Observation of Freeze-Fracture Replicas of Both Sides of the Fracture . . . . . 49 Armen H. Tashjian and Frank C. Bancroft and Lawrence Levine Production of Both Prolactin and Growth Hormone by Clonal Strains of Rat Pituitary Tumor Cells . . . . . . . . . 61 J. M. Papadimitriou and P. Van Duijn Effects of Fixation and Substrate Protection on the Isoenzymes of Aspartate Aminotransferase Studied in a Quantitative Cytochemical Model System 71 J. M. Papadimitriou and P. Van Duijn The Ultrastructural Localization of the Isozymes of Aspartate Aminotransferase in Murine Tissues . . . . . . . . . . . 84 Jean H. Priest and Robert H. Shikes Distribution of Labeled Chromatin . . . 99 S. Schiaffino and V\vera Hanzlíková and Sandra Pierobon Relations Between Structure and Function in Rat Skeletal Muscle Fibers . . . . . 107 Samuel B. Horowitz and I. Robert Fenichel Analysis of Sodium Transport in the Amphibian Oocyte by Extractive and Radioautographic Techniques . . . . . . 120 O. Wesley McBride and Elbert A. Peterson Separation of Nuclei Representing Different Phases of the Growth Cycle from Unsynchronized Mammalian Cell Cultures . . . . . . . . . . . . . . . . 132 Martin I. Sachs and Everett Anderson A Cytological Study of Artificial Parthenogenesis in the Sea Urchin \bionameArbacia Punctulata . . . . . . . 140 Fred D. Warner New Observations on Flagellar Fine Structure . . . . . . . . . . . . . . . 159 Robert V. Rice and Joan A. Moses and G. M. McManus and Arlene C. Brady and Lorraine M. Blasik The Organization of Contractile Filaments in a Mammalian Smooth Muscle 183 Peter B. Armstrong A Fine Structural Study of Adhesive Cell Junctions in Heterotypic Cell Aggregates 197 J. Y. Haga and M. G. Hamilton and M. L. Petermann Electron Microscopic Observations on the Large Subunit of the Rat Liver Ribosome 211 Philip L. Ballard and Gordon M. Tomkins Glucocorticoid-Induced Alteration of the Surface Membrane of Cultured Hepatoma Cells . . . . . . . . . . . . . . . . . 222 Brian S. Spooner and Bernt T. Walther and William J. Rutter The Development of the Dorsal and Ventral Mammalian Pancreas in Vivo and in Vitro . . . . . . . . . . . . . . . . 235 H. Dariush Fahimi The Fine Structural Localization of Endogenous and Exogenous Peroxidase Activity in Kupffer Cells of Rat Liver 247 M. M. Magalhães and Antonio Coimbra Electron Microscope Radioautographic Study of Glycogen Synthesis in the Rabbit Retina . . . . . . . . . . . . . 263 Peter A. Nickerson and Floyd R. Skelton and Agostino Molteni Observation of Filaments in the Adrenal of Androgen-Treated Rats . . . . . . . . 277 Rudolf Vracko and Earl P. Benditt Capillary Basal Lamina Thickening . . . 281 Gerhard Schreiber and Rainer Lesch and Ursula Weinssen and Josef Zähringer The Distribution of Albumin Synthesis Throughout the Liver Lobule . . . . . . 285 B. Hellman and I.-B. Täljedal Solubilizing Effect of Nucleotides on Isolated Insulin Secretory Granules . . 289 Dorothea Zucker-Franklin The Submembranous Fibrils of Human Blood Platelets . . . . . . . . . . . . . . . 293 R. G. Kessel The Permeability of Dragonfly Malpighian Tubule Cells to Protein Using Horseradish Peroxidase As a Tracer . . . 299 C. Ward Kischer and Joe S. Keeter Prostaglandin-B$_1$, Embryonic Skin, and the Dermo--Epidermal Junction . . . . . 303 Roslyn B. Weinstein and Elizabeth D. Hay Deoxyribonucleic Acid Synthesis and Mitosis in Differentiated Cardiac Muscle Cells of Chick Embryos . . . . . . . . . 310
Anders Hamberger and Hans-Arne Hansson and Johan Sjöstrand Surface Structure of Isolated Neurons 319 Satoru Murakami and Lester Packer Protonation and Chloroplast Membrane Structure . . . . . . . . . . . . . . . 332 Jacques Padawer The Reaction of Rat Mast Cells to Polylysine . . . . . . . . . . . . . . . 352 W. J. Larsen Genesis of Mitochondria in Insect Fat Body . . . . . . . . . . . . . . . . . . 373 Joel B. Kirkpatrick and Lyon Hyams and Virginia L. Thomas and Peter M. Howley Purification of Intact Microtubules from Brain . . . . . . . . . . . . . . . . . 384 John A. Kloetzel Compartmentalization of the Developing Macronucleus Following Conjugation in Stylonychia and Euplotes . . . . . . . . 395 Lewis G. Tilney and Robert R. Cardell Factors Controlling the Reassembly of the Microvillous Border of the Small Intestine of the Salamander . . . . . . 408 Thomas L. Lentz Development of the Neuromuscular Junction . . . . . . . . . . . . . . . . 423 Trudy M. Forte and John G. Forte Histochemical Staining and Characterization of Glycoproteins in Acid-Secreting Cells of Frog Stomach . . 437 K. D. Ley and R. A. Tobey Regulation of Initiation of DNA Synthesis in Chinese Hamster Cells . . . 453 Kuruganti G. Murti and David M. Prescott Micronuclear Ribonucleic Acid in \bionameTetrahymena Pyriformis . . . . . 460 P. Satir and N. B. Gilula The Cell Junction in a Lamellibranch Gill Ciliated Epithelium . . . . . . . . 468 Clara Franzini-Armstrong Studies of the Triad . . . . . . . . . . 488 Charles T. Ladoulis and Thomas J. Gill Physical Chemical Studies on the Specific Interaction of an Acriflavine-Phosphotungstic Acid Complex with Double-Stranded Nucleic Acids . . . 500 Fredric J. Silverblatt and Ruth Ellen Bulger Gap Junctions Occur in Vertebrate Renal Proximal Tubule Cells . . . . . . . . . 513 Evelyn Anagnosti and Henry Tedeschi The Mechanism of Low-Amplitude Orthophosphate-Induced Swelling in Isolated Rat Liver Mitochondria . . . . 520 Edgar F. Carell and Pamela Leban Johnston and Alan R. Christopher Vitamin B$_{12}$ and the Macromolecular Composition of Euglena . . . . . . . . . 525 Gertrude W. Hinsch Possible Role of Intranuclear Membranes in Nuclear-Cytoplasmic Exchange in Spider Crab Oocytes . . . . . . . . . . 531 Charles J. Kovacs and Jack Van't Hof Synchronization of a Proliferative Population in a Cultured Plant Tissue 536 Arthur R. Hand Nerve-Acinar Cell Relationships in the Rat Parotid Gland . . . . . . . . . . . 540 David Shepro and Frank A. Belamarich and Lois Robblee and Francis C. Chao Antimotility Effect of Cytochalasin B Observed in Mammalian Clot Retraction 544 Mary A. Grillo Extracellular Synaptic Vesicles in the Mouse Heart . . . . . . . . . . . . . . 547
Hans Glaumann and Jan L. E. Ericsson Evidence for the Participation of the Golgi Apparatus in the Intracellular Transport of Nascent Albumin in the Liver Cell . . . . . . . . . . . . . . . 555 John R. Kennedy and Arthur M. Zimmerman The Effects of High Hydrostatic Pressure on the Microtubules of \bionameTetrahymena Pyriformis . . . . . 568 J. J. Kennelly and R. H. Foote and R. C. Jones Duration of Premeiotic Deoxyribonucleic Acid Synthesis and the Stages of Prophase I in Rabbit Oocytes . . . . . . 577 George D. Bittner and Donald Kennedy Quantitative Aspects of Transmitter Release . . . . . . . . . . . . . . . . 585 A. Gedeon Matoltsy and Margit N. Matoltsy The Chemical Nature of Keratohyalin Granules of the Epidermis . . . . . . . 593 Oscar Touster and N. N. Aronson and John T. Dulaney and Herman Hendrickson Isolation of Rat Liver Plasma Membranes 604 Martin A. Gorovsky Studies on Nuclear Structure and Function in \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 619 Martin A. Gorovsky Studies on Nuclear Structure and Function in \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 631 Sosamma J. Berger and Bertram Sacktor Isolation and Biochemical Characterization of Brush Borders from Rabbit Kidney . . . . . . . . . . . . . 637 Frank J. Longo and Everett Anderson A Cytological Study of the Relation of the Cortical Reaction to Subsequent Events of Fertilization in Urethane-Treated Eggs of the Sea Urchin, \bionameArbacia Punctulata . . . . . . . 646 Hans E. Rugstad and Stephen H. Robinson and Claudine Yannoni and Armen H. Tashjian Metabolism of Bilirubin by a Clonal Strain of Rat Hepatoma Cells . . . . . . 703 Everett Anderson A Cytological Study of the Centrifuged Whole, Half, and Quarter Eggs of the Sea Urchin \bionameArbacia Punctulata . . . 711 Thoru Pederson and Elliott Robbins RNA Synthesis in HeLa Cells . . . . . . 734 Albert Claude Growth and Differentiation of Cytoplasmic Membranes in the Course of Lipoprotein Granule Synthesis in the Hepatic Cell . . . . . . . . . . . . . . 745 N. Scott McNutt and Ronald S. Weinstein The Ultrastructure of the Nexus . . . . 666 Hartmut C. Renger and David R. Wolstenholme Kinetoplast Deoxyribonucleic Acid of the Hemoflagellate Trypanosoma Lewisi . . . 689 G. Lawrence Vankin and E. Michael Brandt and William DeWitt Ultrastructural Studies of Red Blood Cells from Thyroxin-Treated \bionameRana Catesbeiana Tadpoles . . . . . . . . . . 767 Volker Speth and Frank Wunderlich The Macronuclear Envelope of \bionameTetrahymena Pyriformis Gl in Different Physiological States . . . . . 772 Brian Coyne and Joel L. Rosenbaum Flagellar Elongation and Shortening in Chlamydomonas . . . . . . . . . . . . . 777 Trudy M. Forte and John G. Forte Definition of the Extracellular Space in Secreting and Nonsecreting Oxyntic Cells 782 Eve Barak Briles and Alexander Tomasz Radioautographic Evidence for Equatorial Wall Growth in a Gram-Positive Bacterium 786 Martin Hagopian Contraction Bands at Short Sarcomere Length in Chick Muscle . . . . . . . . . 790 Karl T. Kleeman and J. L. Fryer and K. S. Pilcher Observed Differences in CO$_2$ Requirements Between Mammalian and Salmonid Fish Cell Lines . . . . . . . . 796
Edward W. Millhouse and John J. Chiakulas and Lawrence E. Scheving Long-Term Organ Culture of the Salamander Heart . . . . . . . . . . . . 1 Charles N. David and Kenneth Easterbrook Ferritin in the Fungus Phycomyces . . . 15 Nicholas J. Gross Control of Mitochondrial Turnover Under the Influence of Thyroid Hormone . . . . 29 Gerd G. Maul and J. A. Brumbaugh On the Possible Function of Coated Vesicles in Melanogenesis of the Regenerating Fowl Feather . . . . . . . 41 R. J. Baskin Ultrastructure and Calcium Transport in Crustacean Muscle Microsomes . . . . . . 49 M. Locke and J. T. McMahon The Origin and Fate of Microbodies in the Fat Body of an Insect . . . . . . . 61 Peter R. Dallman and Joseph R. Goodman The Effects of Iron Deficiency on the Hepatocyte: a Biochemical and Ultrastructural Study . . . . . . . . . 79 François M. M. Morel and Richard F. Baker and Harold Wayland Quantitation of Human Red Blood Cell Fixation by Glutaraldehyde . . . . . . . 91 R. A. Leyton and E. H. Sonnenblick Cardiac Muscle of the Horseshoe Crab, Limulus Polyphemus . . . . . . . . . . . 101 E. Egyházi and B. Daneholt and J.-E. Edström and B. Lambert and U. Ringborg Intracellular Distribution of Low Molecular Weight RNA in Chironomus Tentans . . . . . . . . . . . . . . . . 120 Yutaka Shimada Electron Microscope Observations on the Fusion of Chick Myoblasts in Vitro . . . 128 Birgit Satir and Ellen Roter Dirksen Nucleolar Aging in \bionameTetrahymena During the Cultural Growth Cycle . . . . 143 David T. Moran and Kent M. Chapman and Richard A. Ellis The Fine Structure of Cockroach Campaniform Sensilla . . . . . . . . . . 155 Jack Rosenbluth Myosin-Like Aggregates in Trypsin-Treated Smooth Muscle Cells . . 174 John H. Youson Prismatic Cristae and Matrix Granules in Mitochondria of the Kidneys of Ammocoetes . . . . . . . . . . . . . . . 189 B. K. Ghosh Grooves in the Plasmalemma of \bionameSaccharomyces Cerevisiae Seen in Glancing Sections of Double Aldehyde-Fixed Cells . . . . . . . . . . 192 C. J. Bentzel and D. R. Tourville and B. Parsa and T. B. Tomasi Bidirectional Transport of Horseradish Peroxidase in Proximal Tubule of Necturus Kidney . . . . . . . . . . . . 197 Samar Chatterjee and Lester Goldstein Proteins in Nucleocytoplasmic Interactions . . . . . . . . . . . . . . 202 C. C. Clawson and Robert A. Good Micropapillae . . . . . . . . . . . . . 207 J. Robert Waaland and Susan Drury Waaland and Daniel Branton Gas Vacuoles . . . . . . . . . . . . . . 212 Thomas D. Pollard and Edward D. Korn Filaments of Amoeba Proteus . . . . . . 216 N. Nanninga The Mesosome of Bacillus Subtilis As Affected by Chemical and Physical Fixation . . . . . . . . . . . . . . . . 219
Brian S. Spooner and S. Robert Hilfer The Expression of Differentiation by Chick Embryo Thyroid in Cell Culture . . 225 Camillo A. Benzo and Andrew M. Nemeth Factors Controlling Development of Chick Embryo Liver Cells During Organ Culture 235 S. H. Socher and D. Davidson $5$-Aminouracil Treatment . . . . . . . 248 G. A. Mueller and Mary Esther Gaulden and Wanzer Drane The Effects of Varying Concentrations of Colchicine on the Progression of Grasshopper Neuroblasts into Metaphase 253 William H. Massover Intramitochondrial Yolk-Crystals of Frog Oocytes . . . . . . . . . . . . . . . . 266 E. Gantt and M. R. Edwards and L. Provasoli Chloroplast Structure of the Cryptophyceae . . . . . . . . . . . . . 280 D. R. Myron and J. L. Connelly The Morphology of the Swelling Process in Rat Liver Mitochondria . . . . . . . 291 Steven J. Hausman and Lucy M. Anderson and William H. Telfer The Dependence of Cecropia Yolk Formation in Vitro on Specific Blood Proteins . . . . . . . . . . . . . . . . 303 Abraham L. Kierszenbaum and Cesar M. Libanati and Carlos J. Tandler The Distribution of Inorganic Cations in Mouse Testis . . . . . . . . . . . . . . 314 Thomas Bibring and Jane Baxandall Selective Extraction of Isolated Mitotic Apparatus . . . . . . . . . . . . . . . 324 Ellen Kundrat and Frank A. Pepe The M Band . . . . . . . . . . . . . . . 340 Henry deF. Webster The Geometry of Peripheral Myelin Sheaths During Their Formation and Growth in Rat Sciatic Nerves . . . . . . 348 J. H. Hardin and S. S. Spicer Ultrastructural Localization of Dialyzed Iron-Reactive Mucosubstance in Rabbit Heterophils, Basophils, and Eosinophils 368 Hilton H. Mollenhauer and Clara Totten Studies on Seeds . . . . . . . . . . . . 387 Hilton H. Mollenhauer and Clara Totten Studies on Seeds . . . . . . . . . . . . 395 Awtar Krishan and Dora Hsu Binding of Colchicine-$^3$H to Vinblastine- and Vincristine-Induced Crystals in Mammalian Tissue Culture Cells . . . . . . . . . . . . . . . . . 407 Michael K. Nemanic and Dorothy R. Pitelka A Scanning Electron Microscope Study of the Lactating Mammary Gland . . . . . . 410 A. Macieira-Coelho and D. Brouty-Boyé and M. T. Thomas and I. Gresser Interferon and Cell Division . . . . . . 415 J. D. Hall and F. L. Crane Intracristal Rods . . . . . . . . . . . 420 Fotis C. Kafatos and Vassili Kiortsis The Packaging of a Secretory Protein . . 426 Ronald D. MacDonald and Andrew G. Engel Observations on Organization of Z-Disk Components and on Rod-Bodies of Z-Disk Origin . . . . . . . . . . . . . . . . . 431 Lawrence L. Espey Multivesicular Structures in Proliferating Fibroblasts of Rabbit Ovarian Follicles During Ovulation . . . 437
A. R. Stevens and D. M. Prescott Reformation of Nucleolus-Like Bodies in the Absence of Postmitotic RNA Synthesis 443 Thomas L. Lentz and J. P. Trinkaus Differentiation of the Junctional Complex of Surface Cells in the Developing Fundulus Blastoderm . . . . . 455 Russell L. Deter Quantitative Characterization of Dense Body, Autophagic Vacuole, and Acid Phosphatase-Bearing Particle Populations During the Early Phases of Glucagon-Induced Autophagy in Rat Liver 473 S. Jakovcic and G. S. Getz and M. Rabinowitz and H. Jakob and H. Swift Cardiolipin Content of Wild Type and Mutant Yeasts in Relation to Mitochondrial Function and Development 490 James D. Jamieson and George E. Palade Condensing Vacuole Conversion and Zymogen Granule Discharge in Pancreatic Exocrine Cells: Metabolic Studies . . . 503 Yasusada Miura and Fred H. Wilt The Effects of $5$-Bromodeoxyuridine on Yolk Sac Erythropoiesis in the Chick Embryo . . . . . . . . . . . . . . . . . 523 Hilton H. Mollenhauer and Clara Totten Studies on Seeds . . . . . . . . . . . . 533 C. Freeman Allen and Pearl Good and Hilton H. Mollenhauer and Clara Totten Studies on Seeds . . . . . . . . . . . . 542 Adolph I. Cohen Electron Microscope Observations on Form Changes in Photoreceptor Outer Segments and Their Saccules in Response to Osmotic Stress . . . . . . . . . . . . . 547 Ken Shortman and Neil Williams and Heather Jackson and Pamela Russell and Pauline Byrt and E. Diener The Separation of Different Cell Classes from Lymphoid Organs . . . . . . . . . . 566 R. Seegmiller and F. C. Fraser and H. Sheldon A New Chondrodystrophic Mutant in Mice 580 Ursula W. Goodenough and L. Andrew Staehelin Structural Differentiation of Stacked and Unstacked Chloroplast Membranes . . 594 Werner Straus Comparative Analysis of the Concentration of Injected Horseradish Peroxidase in Cytoplasmic Granules of the Kidney Cortex, in the Blood, Urine, and Liver . . . . . . . . . . . . . . . 620 Joram Heller and Thomas J. Ostwald and Dean Bok The Osmotic Behavior of Rod Photoreceptor Outer Segment Discs . . . 633 Olivia C. McKenna and Jack Rosenbluth Characterization of an Unusual Catecholamine-Containing Cell Type in the Toad Hypothalamus . . . . . . . . . 650 Ruben Laguens Morphometric Study of Myocardial Mitochondria in the Rat . . . . . . . . 673 John W. Combs An Electron Microscope Study of Mouse Mast Cells Arising in Vivo and in Vitro 676 Alain Perrelet and Lelio Orci and Fritz Baumann Evidence for Granulolysis in the Retinula Cells of a Stomatopod Crustacean, Squilla Mantis . . . . . . . 684 Robert L. Trelstad Vacuoles in the Embryonic Chick Corneal Epithelium, an Epithelium Which Produces Collagen . . . . . . . . . . . . . . . . 689 Jared Grantham and F. E. Cuppage and Darrell Fanestil Direct Observation of Toad Bladder Response to Vasopressin . . . . . . . . 695 Takashi Iwayama and J. B. Furness Enhancement of the Granulation of Adrenergic Storage Vesicles in Drug-Free Solution . . . . . . . . . . . . . . . . 699 Jochen W. Heine and Carl A. Schnaitman A Method for the Isolation of Plasma Membrane of Animal Cells . . . . . . . . 703 David Bodian Presynaptic Organelles and Junctional Integrity . . . . . . . . . . . . . . . 707 Robert L. Benson and Bertram Sacktor and John W. Greenawalt Studies on the Ultrastructural Localization of Intestinal Disaccharidases . . . . . . . . . . . . 711
Richard D. Allen Fine Structure of Membranous and Microfibrillar Systems in the Cortex of Paramecium Caudatum . . . . . . . . . . 1 Gordon R. Campbell and Yasuo Uehara and Gerda Mark and Geoffrey Burnstock Fine Structure of Smooth Muscle Cells Grown in Tissue Culture . . . . . . . . 21 Colvin M. Redman Phospholipid Metabolism in Intact and Modified Erythrocyte Membranes . . . . . 35 Paul H. Jewett and J. R. Sommer and E. A. Johnson Cardiac Muscle . . . . . . . . . . . . . 50 Mina Perlin and Jules V. Hallum Effect of acid pH on macromolecular synthesis in L cells . . . . . . . . . . 66 Paula M. Orkand and Edward A. Kravitz Localization of the sites of $ \gamma $-aminobutyric acid (GABA) uptake in lobster nerve--muscle preparations . . . 75 E. M. Eddy and Susumu Ito Fine Structural and Radioautographic Observations on Dense Perinuclear Cytoplasmic Material in Tadpole Oocytes 90 J. Meldolesi and J. D. Jamieson and G. E. Palade Composition of Cellular Membranes in the Pancreas of the Guinea Pig . . . . . . . 109 J. Meldolesi and J. D. Jamieson and G. E. Palade Composition of Cellular Membranes in the Pancreas of the Guinea Pig . . . . . . . 130 J. Meldolesi and J. D. Jamieson and G. E. Palade Composition of Cellular Membranes in the Pancreas of the Guinea Pig . . . . . . . 150 Y. Asada and M. V. L. Bennett Experimental Alteration of Coupling Resistance at an Electrotonic Synapse 159 George D. Pappas and Y. Asada and M. V. L. Bennett Morphological Correlates of Increased Coupling Resistance at an Electrotonic Synapse . . . . . . . . . . . . . . . . 173 K. D. Stuart Evidence for the Retention of Kinetoplast DNA in an Acriflavine-Induced Dyskinetoplastic Strain of Trypanosoma Brucei Which Replicates the Altered Central Element of the Kinetoplast . . . . . . . . . . . 189 Clara Franzini-Armstrong Studies of the Triad . . . . . . . . . . 196 Robert C. Shaler and Richard L. McCarl The Mechanism of Cortisol Action in Cultured Rat Heart Cells . . . . . . . . 205 G. M. Vassart and J. E. Dumont and F. R. L. Cantraine Interpretation of Surface Aspects of Cell Sections . . . . . . . . . . . . . 210 Hilton H. Mollenhauer Fragmentation of Mature \bionameDictyosome Cisternae . . . . . . 212 Ronald J. Przybylski Occurrence of Centrioles During Skeletal and Cardiac Myogenesis . . . . . . . . . 214 Charles J. Flickinger Decreased Formation of Golgi Bodies in Amebae in the Presence of RNA and Protein Synthesis Inhibitors . . . . . . 221 Virginia G. Fonte and Robert L. Searls and S. Robert Hilfer The Relationship of Cilia with Cell Division and Differentiation . . . . . . 226 J. D. Chapman and R. G. Webb and J. Borsa ATP Pool Levels in Synchronously Growing Chinese Hamster Cells . . . . . . . . . 229
K. J. Ryan and H. Kalant and E. Llewellyn Thomas Free-Flow Electrophoretic Separation and Electrical Surface Properties of Subcellular Particles from Guinea Pig Brain . . . . . . . . . . . . . . . . . 235 Walter S. Krawczyk A Pattern of Epidermal Cell Migration During Wound Healing . . . . . . . . . . 247 A. Leskes and P. Siekevitz and G. E. Palade Differentiation of Endoplasmic Reticulum in Hepatocytes . . . . . . . . . . . . . 264 A. Leskes and P. Siekevitz and G. E. Palade Differentiation of Endoplasmic Reticulum in Hepatocytes . . . . . . . . . . . . . 288 Richard W. Young The Renewal of Rod and Cone Outer Segments in the Rhesus Monkey . . . . . 303 Eveline E. Schneeberger and Morris J. Karnovsky The Influence of Intravascular Fluid Volume on the Permeability of Newborn and Adult Mouse Lungs to Ultrastructural Protein Tracers . . . . . . . . . . . . 319 A. M. Kelly Sarcoplasmic Reticulum and T Tubules in Differentiating Rat Skeletal Muscle . . 335 Hilary K. Darrah and John Hedley-Whyte and E. Tessa Hedley-Whyte Radioautography of Cholesterol in Lung 345 Pat G. Model and Murray B. Bornstein and Stanley M. Crain and George D. Pappas An Electron Microscopic Study of the Development of Synapses in Cultured Fetal Mouse Cerebrum Continuously Exposed to Xylocaine . . . . . . . . . . 362 George M. Maniatis and Vernon M. Ingram Erythropoiesis During Amphibian Metamorphosis . . . . . . . . . . . . . 372 George M. Maniatis and Vernon M. Ingram Erythropoiesis During Amphibian Metamorphosis . . . . . . . . . . . . . 380 George M. Maniatis and Vernon M. Ingram Erythropoiesis During Amphibian Metamorphosis . . . . . . . . . . . . . 390 Arthur R. Ugel Studies on Isolated Aggregating Oligoribonucleoproteins of the Epidermis with Histochemical and Morphological Characteristics of Keratohyalin . . . . 405 Madhu M. Bhargava and Harlyn O. Halvorson Isolation of Nuclei from Yeast . . . . . 423 E. A. Comissiong and D. W. Stanley and H. O. Hultin Inhibition of Emptying of Skeletal Muscle Cell Segments by Adenine Nucleotides and Polyvalent Cations . . . 430 Heschel J. Raskas and Case K. Okubo Transport of Viral RNA in Kb Cells Infected with Adenovirus Type 2 . . . . 438 K. E. Kuettner and R. Eisenstein and L. W. Soble and C. Arsenis Lysozyme in Epiphyseal Cartilage . . . . 450 C. Arsenis and R. Eisenstein and L. W. Soble and K. E. Kuettner Enzyme Activities in Chick Embryonic Cartilage . . . . . . . . . . . . . . . 459 J. Richard McIntosh and Story C. Landis The Distribution of Spindle Microtubules During Mitosis in Cultured Human Cells 468 V. L. Rudick Relationships Between Nucleic Acid Synthetic Patterns and Encystment in Aging Unagitated Cultures of \bionameAcanthamoeba Castellanii . . . . 498 Fathy E. Mattar and Thomas J. Byers Morphological Changes and the Requirements for Macromolecule Synthesis During Excystment of \bionameAcanthamoeba Castellanii . . . . 507 Takashi Iwayama Nexuses Between Areas of the Surface Membrane of the Same Arterial Smooth Muscle Cell . . . . . . . . . . . . . . 521 Robert J. Pariser and Dennis D. Cunningham Transport Inhibitors Released by 3T3 Mouse Cells and Their Relation to Growth Control . . . . . . . . . . . . . . . . 525 F. Malaisse-Lagae and M. H. Greider and W. J. Malaisse and P. E. Lacy The Stimulus-Secretion Coupling of Glucose-Induced Insulin Release . . . . 530 William E. Cassady and Robert P. Wagner Separation of Mitochondrial Membranes of Neurospora Crassa . . . . . . . . . . . 536 R. Lenk and S. Penman Morphological Studies of Cells Grown in the Absence of Mitochondrial-Specific Protein Synthesis . . . . . . . . . . . 541 Henry B. Horwitz and Charles E. Holt Specific Inhibition by Ethidium Bromide of Mitochondrial DNA Synthesis in \bionamePhysarum Polycephalum . . . . . 546 Woutera van Iterson and J. B. Groen DNA-Membrane Complexes of Bacillus Subtilis . . . . . . . . . . . . . . . . 553 John Oberpriller and Jean C. Oberpriller Mitosis in Adult Newt Ventricle . . . . 560 N. Nanninga Uniqueness and Location of the Fracture Plane in the Plasma Membrane of Bacillus Subtilis . . . . . . . . . . . . . . . . 564
Q. Bone and E. J. Denton The Osmotic Effects of Electron Microscope Fixatives . . . . . . . . . . 571 Sandra K. Masur and Eric Holtzman and Irving L. Schwartz and Roderich Walter Correlation Between Pinocytosis and Hydroosmosis Induced by Neurohypophyseal Hormones and Mediated by Adenosine 3',5'-Cyclic Monophosphate . . . . . . . 582 Brian S. Spooner and Kenneth M. Yamada and Norman K. Wessells Microfilaments and Cell Locomotion . . . 595 Kenneth M. Yamada and Brian S. Spooner and Norman K. Wessells Ultrastructure and Function of Growth Cones and Axons of Cultured Nerve Cells 614 Carrick E. Devine and Andrew P. Somlyo Thick Filaments in Vascular Smooth Muscle . . . . . . . . . . . . . . . . . 636 H. Clarke Anderson and Stanley W. Sajdera The Fine Structure of Bovine Nasal Cartilage . . . . . . . . . . . . . . . 650 Dean Bok and Michael O. Hall The Role of the Pigment Epithelium in the Etiology of Inherited Retinal Dystrophy in the Rat . . . . . . . . . . 664 Se Yong Lee and Velibor Krsmanovic and George Brawerman Attachment of Ribosomes to Membranes During Polysome Formation in Mouse Sarcoma 180 Cells . . . . . . . . . . . 683 Brigid Hogan and Paul R. Gross The Effect of Protein Synthesis Inhibition on the Entry of Messenger RNA into the Cytoplasm of Sea Urchin Embryos 692 Sharon V. Radford and Donald W. Misch The Cytological Effect of Ecdysterone on the Midgut Cells of the Flesh-Fly Sarcophaga Bullata . . . . . . . . . . . 702 Yoshinori Nozawa and Guy A. Thompson Studies of Membrane Formation in \bionameTetrahymena Pyriformis . . . . . 712 Yoshinori Nozawa and Guy A. Thompson Studies of Membrane Formation in \bionameTetrahymena Pyriformis . . . . . 722 W. Bernhard and Annie Viron Improved Techniques for the Preparation of Ultrathin Frozen Sections . . . . . . 731 Barbara Szubinska ''New Membrane'' Formation in Amoeba Proteus Upon Injury of Individual Cells 747 Yvonne Kress and Murray Wittner and Robert M. Rosenbaum Sites of Cytoplasmic Ribonucleoprotein-Filament Assembly in Relation to Helical Body Formation in Axenic Trophozoites of Entamoeba Histolytica . . . . . . . . . . . . . . 773 Stephanie G. Phillips and David M. Phillips Nucleoli of Diploid Cell Strains . . . . 785 David M. Phillips and Stephanie G. Phillips Distinctive Characteristics of Nucleoli of Two Established Cell Lines . . . . . 803 Jean-Claude Wanson and Louis Tielemans Morphological and Biochemical Characteristics of Glycogen Particles Isolated from Rabbit Polymorphonuclear Leukocytes . . . . . . . . . . . . . . . 816 J. S. Noel and W. C. Dewey and J. H. Abel and R. P. Thompson Ultrastructure of the Nucleolus During the Chinese Hamster Cell Cycle . . . . . 830 Stephen E. Malawista The Melanocyte Model . . . . . . . . . . 848 A. Haddad and Meredith D. Smith and Annette Herscovics and N. J. Nadler and C. P. Leblond Radioautographic Study of in Vivo and in Vitro Incorporation of Fucose-$^3$H into Thyroglobulin by Rat Thyroid Follicular Cells . . . . . . . . . . . . . . . . . 856 A. Nakamura and F. Sreter and J. Gergely Comparative Studies of Light Meromyosin Paracrystals Derived from Red, White, and Cardiac Muscle Myosins . . . . . . . 883 R. D. Cheetham and D. James Morré and Carol Pannek and Daniel S. Friend Isolation of a Golgi Apparatus-Rich Fraction from Rat Liver . . . . . . . . 899 Ronald C. Rustad and Shuhei Yuyama and Lynne C. Rustad Nuclear-Cytoplasmic Relations in the Mitosis of Sea Urchin Eggs . . . . . . . 906 R. Meneghini and H. A. Armelin and J. Balsamo and F. J. S. Lara Indication of Gene Amplification in Rhynchosciara by RNA-DNA Hybridization 913 Morton H. Friedman Arm-Bearing Microtubules Associated with an Unusual Desmosome-Like Junction . . . 916 E. Brad Thompson and Gordon M. Tomkins A Histochemical Method for the Demonstration of Tyrosine Aminotransferase in Tissue Culture Cells, and Studies of This Enzyme in Hepatoma Tissue Culture Cells . . . . . 921 Awtar Krishan and Dora Hsu Vinblastine-Induced Ribosomal Complexes 927 Mary Bell A Comparative Study of Sebaceous Gland Ultrastructure in Subhuman Primates . . 932 D. M. Woolley Striations in the Peripheral Fibers of Rat and Mouse Spermatozoa . . . . . . . 936 Tsuneyoshi Kuroiwa and Nobunori Tanaka Fine Structures of Interphase Nuclei . . 939 Thoru Pederson and Elliott Robbins A Method for Improving Synchrony in the G$_2$ Phase of the Cell Cycle . . . . . 942 John R. Hodgson and Harold W. Fisher Formation of Polyribosomes During Recovery from Contact Inhibition of Replication . . . . . . . . . . . . . . 945 Jean-Marie Gillis and Maurice Wibo Accurate Measurement of the Thickness of Ultrathin Sections by Interference Microscopy . . . . . . . . . . . . . . . 947 I. W. Craig and A. Gibor Chloroplast Development in Charophyceae 950
LeRoy Kuehl and Earl N. Sumsion Studies on the Site of Synthesis of Several Soluble Enzymes of the Cell Nucleus . . . . . . . . . . . . . . . . 1 George E. Palade Albert Claude and the Beginnings of Biological Electron Microscopy . . . . . ?? Richard G. W. Anderson and Robert M. Brenner The Formation of Basal Bodies (Centrioles) in the Rhesus Monkey Oviduct . . . . . . . . . . . . . . . . 10 Christian de Duve Tissue Fraction-Past and Present . . . . ?? Ursula W. Goodenough The Effects of Inhibitors of RNA and Protein Synthesis on Chloroplast Structure and Function in Wild-Type Chlamydomonas Reinhardi . . . . . . . . 35 Ursula W. Goodenough and R. P. Levine The effects of inhibitors of RNA and protein synthesis on the recovery of chloroplast ribosomes, membrane organization, and photosynthetic electron transport in the \bionameac-20 strain of \bionameChlamydomonas reinhardi . . . . . . . . . . . . . . . 50 Gary G. Leppard and J. Ross Colvin and Dyson Rose and S. M. Martin Lignofibrils on the External Cell Wall Surface of Cultured Plant Cells . . . . 63 Daniel A. Goodenough and Jean-Paul Revel The Permeability of Isolated and in Situ Mouse Hepatic Gap Junctions Studied with Enzymatic Tracers . . . . . . . . . . . 81 A. J. Hudspeth and J. P. Revel Coexistence of Gap and Septate Junctions in an Invertebrate Epithelium . . . . . 92 Joan A. Higgins and Russell J. Barrnett Fine Structural Localization of Acyltransferases . . . . . . . . . . . . 102 Yasuko Nakajima Fine Structure of the Medial Nucleus of the Trapezoid Body of the Bat with Special Reference to Two Types of Synaptic Endings . . . . . . . . . . . . 121 James D. Jamieson and George E. Palade Synthesis, Intracellular Transport, and Discharge of Secretory Proteins in Stimulated Pancreatic Exocrine Cells . . 135 Russell Ross and Seymour J. Klebanoff The Smooth Muscle Cell . . . . . . . . . 159 Russell Ross The Smooth Muscle Cell . . . . . . . . . 172 Abraham Amsterdam and Michael Schramm and Itzhak Ohad and Yoram Salomon and Zvi Selinger Concomitant Synthesis of Membrane Protein and Exportable Protein of the Secretory Granule in Rat Parotid Gland 187 Winston A. Anderson and Andrew Spielman Permeability of the Ovarian Follicle of Aedes Aegypti Mosquitoes . . . . . . . . 201 D. Montgomery Bissell and Jeremiah G. Tilles Morphology and Function of Cells of Human Embryonic Liver in Monolayer Culture . . . . . . . . . . . . . . . . 222 Jeanne Pager Étude Morphométrique du Syst\`eme Tubulaire Transverse du Myocarde Ventriculaire de Rat. (French) [Morphometric Study of the Transverse Tubular System of Rat Ventricular Myocardium] . . . . . . . . . . . . . . 233 Gary G. Leppard and J. Ross Colvin Fine Structure of the Middle Lamella of Aggregates of Plant Cells in Suspension Culture . . . . . . . . . . . . . . . . 237 M. S. Shahrabadi and T. Yamamoto A Method for Staining Intracellular Antigens in Thin Sections with Ferritin-Labeled Antibody . . . . . . . 246 George R. Hunter and Gerald P. Brierley On the ``Energized-Twisted'' Configuration of Isolated Beef Heart Mitochondria . . . . . . . . . . . . . . 250 John A. Hermos and Minnie Mathan and Jerry S. Trier DNA Synthesis and Proliferation by Villous Epithelial Cells in Fetal Rats 255 Garth L. Nicolson Structure of the Photosynthetic Apparatus in Protein-Embedded Chloroplasts . . . . . . . . . . . . . . 258 H. L. Atwood Z and T Tubules in Stomach Muscles of the Spiny Lobster . . . . . . . . . . . 264 I. Friedberg and I. Goldberg and I. Ohad A Prolamellar Body-Like Structure in Chlamydomonas Reinhardi . . . . . . . . 268
A. Martinez-Palomo and D. Erlij and H. Bracho Localization of Permeability Barriers in the Frog Skin Epithelium . . . . . . . . 277 G. Niemeyer and W. G. Forssmann Comparison of Glycerol Treatment in Frog Skeletal Muscle and Mammalian Heart . . 288 Lee V. Leak Studies on the Permeability of Lymphatic Capillaries . . . . . . . . . . . . . . 300 M. M. Salpeter and E. E. Salpeter Resolution in Electron Microscope Radioautography . . . . . . . . . . . . 324 H. Reggio and H. Cailla-Deckmyn and G. Marchis-Mouren Effect of Pancreozymin on Rat Pancreatic Enzyme Biosynthesis . . . . . . . . . . 333 Peter B. Moens and Ellen Rapport Spindles, Spindle Plaques, and Meiosis in the Yeast \bionameSaccharomyces Cerevisiae (Hansen) . . . . . . . . . . 344 G. Benjamin Bouck The Structure, Origin, Isolation, and Composition of the Tubular Mastigonemes of the Ochromonas Flagellum . . . . . . 362 Genevieve S. Incefy and Attallah Kappas Isolation and Biochemical Characterization of Nuclei from Chick Embryo Liver . . . . . . . . . . . . . . 385 Walter Rubin and Michael D. Gershon and Leonard L. Ross Electron Microscope Radioautographic Identification of Serotonin-Synthesizing Cells in the Mouse Gastric Mucosa . . . 399 B. R. Brinkley and Joiner Cartwright Ultrastructural Analysis of Mitotic Spindle Elongation in Mammalian Cells in Vitro . . . . . . . . . . . . . . . . . 416 J. P. Kraehenbuhl and P. B. De Grandi and M. A. Campiche Ultrastructural Localization of Intracellular Antigen Using Enzyme-Labeled Antibody Fragments . . . 432 P. B. De Grandi and J. P. Kraehenbuhl and M. A. Campiche Ultrastructural localization of calcitonin in the parafollicular cells of pig thyroid gland with cytochrome $c$-labeled antibody fragments . . . . . 446 Judith Medoff and Jerome Gross In Vitro Aggregation of Mixed Embryonic Kidney and Nerve Cells . . . . . . . . . 457 Norton B. Berg and Richard W. Young Sulfate Metabolism in Pancreatic Acinar Cells . . . . . . . . . . . . . . . . . 469 Y. Uehara and G. R. Campbell and G. Burnstock Cytoplasmic Filaments in Developing and Adult Vertebrate Smooth Muscle . . . . . 484 Barbara A. Nichols and Dorothy Ford Bainton and Marilyn G. Farquhar Differentiation of Monocytes . . . . . . 498 Rudolf A. Raff and Gerald Greenhouse and Kenneth W. Gross and Paul R. Gross Synthesis and Storage of Microtubule Proteins by Sea Urchin Embryos . . . . . 516 E. L. Carstensen and William G. Aldridge and S. Z. Child and P. Sullivan and H. H. Brown Stability of Cells Fixed with Glutaraldehyde and Acrolein . . . . . . 529 Harmut C. Renger and David R. Wolstenholme Kinetoplast and other satellite DNAs of kinetoplastic and dyskinetoplastic strains of \bionameTrypanosoma . . . . . 533 M. Locke and N. Krishnan and J. T. McMahon A Routine Method for Obtaining High Contrast Without Staining Sections . . . 540 Elizabeth Gillespie Colchicine Binding in Tissue Slices . . 544 M. Locke and N. Krishnan Hot Alcoholic Phosphotungstic Acid and Uranyl Acetate As Routine Stains for Thick and Thin Sections . . . . . . . . 550 Avinash N. Bhisey and Jerome J. Freed Cross-Bridges on the Microtubules of Cooled Interphase HeLa Cells . . . . . . 557 C. A. Pasternak and A. M. H. Warmsley and D. B. Thomas Structural Alterations in the Surface Membrane During the Cell Cycle . . . . . 562
Lelio Orci and Andre E. Lambert and Yasunori Kanazawa and Mylene Amherdt and Charles Rouiller and Albert E. Renold Morphological and Biochemical Studies of B Cells of Fetal Rat Endocrine Pancreas in Organ Culture . . . . . . . . . . . . 565 Ramah W. La Pushin and Etienne de Harven A Study of Gluco-Corticosteroid-Induced Pyknosis in the Thymus and Lymph Node of the Adrenalectomized Rat . . . . . . . . 583 Richard D. Palmiter and Joan T. Wrenn Interaction of Estrogen and Progesterone in Chick Oviduct Development . . . . . . 598 Nicolae Simionescu and George E. Palade Dextrans and Glycogens As Particulate Tracers for Studying Capillary Permeability . . . . . . . . . . . . . . 616 Francis J. Chlapowski and R. Neal Band Assembly of Lipids into Membranes in \bionameAcanthamoeba Palestinensis . . . 625 Francis J. Chlapowski and R. Neal Band Assembly of Lipids into Membranes in \bionameAcanthamoeba Palestinensis . . . 634 Harold Weintraub and Graham Le M. Campbell and Howard Holtzer Primitive Erythropoiesis in Early Chick Embryogenesis . . . . . . . . . . . . . 652 G. Le M. Campbell and H. Weintraub and B. H. Mayall and H. Holtzer Primitive Erythropoiesis in Early Chick Embryogenesis . . . . . . . . . . . . . 669 Lloyd A. Culp and William J. Grimes and Paul H. Black Contact-Inhibited Revertant Cell Lines Isolated from Sv40-Transformed Cells . . 682 N. Scott McNutt and Lloyd A. Culp and Paul H. Black Contact-Inhibited Revertant Cell Lines Isolated from Sv40-Transformed Cells . . 691 John Rannestad and Norman E. Williams The Synthesis of Microtubule and Other Proteins of the Oral Apparatus in \bionameTetrahymena Pyriformis . . . . . 709 Neil Howell and Carol A. Zuiches and Kenneth D. Munkres Mitochondrial Biogenesis in Neurospora Crassa . . . . . . . . . . . . . . . . . 721 David J. McLaughlin Centrosomes and Microtubules During Meiosis in the Mushroom Boletus Rubinellus . . . . . . . . . . . . . . . 737 Stanley G. Sawicki and Gabriel C. Godman On the Differential Cytotoxicity of Actinomycin D . . . . . . . . . . . . . 746 Chandler Fulton and R. E. Kane and R. E. Stephens Serological Similarity of Flagellar and Mitotic Microtubules . . . . . . . . . . 762 Jay R. Greenberg and Robert P. Perry Hybridization Properties of DNA Sequences Directing the Synthesis of Messenger RNA and Heterogeneous Nuclear RNA . . . . . . . . . . . . . . . . . . 774 C. N. Nair and E. Knight Turnover of HeLa Ribosomal RNA . . . . . 787 Judson D. Sheridan Electrical Coupling Between Fat Cells in Newt Fat Body and Mouse Brown Fat . . . 795 Roger Wagner and Murray Rosenberg and Richard Estensen Endocytosis in Chang Liver Cells . . . . 804 Ronald H. Stevens and Harold Amos RNA Metabolism in HeLa Cells at Reduced Temperature . . . . . . . . . . . . . . 818 C. J. Tandler and A. L. Kierszenbaum Inorganic Cations in Rat Kidney . . . . 830 Robert L. Trelstad and Alfred J. Coulombre Morphogenesis of the Collagenous Stroma in the Chick Cornea . . . . . . . . . . 840 Phyllis M. Novikoff and Alex B. Novikoff and Nelson Quintana and Jean-Jacques Hauw Golgi Apparatus, Gerl, and Lysosomes of Neurons in Rat Dorsal Root Ganglia, Studied by Thick Section and Thin Section Cytochemistry . . . . . . . . . 859 P. M. Rose and A. F. Hopper and R. W. Wannemacher Cell Population Changes in the Intestinal Mucosa of Protein-Depleted Or Starved Rats . . . . . . . . . . . . . . 887 Pieter J. Helmsing and Hans D. Berendes Induced Accumulation of Nonhistone Proteins in Polytene Nuclei of \bionameDrosophila Hydei . . . . . . . . 893 Mercedes R. Edwards and Elisabeth Gantt Phycobilisomes of the Thermophilic Blue-Green Alga Synechococcus Lividus 896 Jack Rosenbluth Myosin-Like Tactoids in Trypsin-Treated Blood Platelets . . . . . . . . . . . . 900 Garth L. Nicolson and Robert Hyman and S. J. Singer The Two-Dimensional Topographic Distribution of H-2 Histocompatibility Alloantigens on Mouse Red Blood Cell Membranes . . . . . . . . . . . . . . . 905
E. Joan Blanchette-Mackie and Robert O. Scow Sites of Lipoprotein Lipase Activity in Adipose Tissue Perfused with Chylomicrons . . . . . . . . . . . . . . 1 Alfred Weinstock and C. P. Leblond Elaboration of the Matrix Glycoprotein of Enamel by the Secretory Ameloblasts of the Rat Incisor As Revealed by Radioautography After Galactose-$^3$H Injection . . . . . . . . . . . . . . . 26 Maurice Wibo and Alain Amar-Costesec and Jacques Berthet and Henri Beaufay Electron Microscope Examination of Subcellular Fractions . . . . . . . . . 52 Ernest W. April and Philip W. Brandt and Gerald F. Elliott The Myofilament Lattice: Studies on Isolated Fibers . . . . . . . . . . . . 72 William K. Ovalle Fine Structure of Rat Intrafusal Muscle Fibers . . . . . . . . . . . . . . . . . 83 Tatsuro Ikeuchi and Mitsuyoshi Sanbe and Herbert Weinfeld and Avery A. Sandberg Induction of Nuclear Envelopes Around Metaphase Chromosomes After Fusion with Interphase Cells . . . . . . . . . . . . 104 Robert D. Leibowitz The Effect of Ethidium Bromide on Mitochondrial DNA Synthesis and Mitochondrial DNA Structure in HeLa Cells . . . . . . . . . . . . . . . . . 116 Charles R. Hackenbrock and Terry G. Rehn and Eugene C. Weinbach and John J. Lemasters Oxidative Phosphorylation and Ultrastructural Transformation in Mitochondria in the Intact Ascites Tumor Cell . . . . . . . . . . . . . . . . . . 123 Howard Feit and Gary R. Dutton and Samuel H. Barondes and Michael L. Shelanski Microtubule Protein . . . . . . . . . . 138 Toshio Nagano and Iwao Ohtsuki Reinvestigation of the Fine Structure of Reinke's Crystal in the Human Testicular Interstitial Cell . . . . . . . . . . . 148 Judy M. Strum and Janice Wicken and John R. Stanbury and Morris J. Karnovsky Appearance and Function of Endogenous Peroxidase in Fetal Rat Thyroid . . . . 162 H. L. Fernandez and P. R. Burton and F. E. Samson Axoplasmic Transport in the Crayfish Nerve Cord . . . . . . . . . . . . . . . 176 Andrew G. Ulsamer and Paddy L. Wright and Mary G. Wetzel and Edward D. Korn Plasma and Phagosome Membranes of \bionameAcanthamoeba Castellanii . . . . 193 Ferenc Hajós and Sándor Kerpel-Fronius Electron Microscope Histochemical Evidence for a Partial Or Total Block of the Tricarboxylic Acid Cycle in the Mitochondria of Presynaptic Axon Terminals . . . . . . . . . . . . . . . 216 Camillo Peracchia and J. David Robertson Increase in Osmiophilia of Axonal Membranes of Crayfish As a Result of Electrical Stimulation, Asphyxia, Or Treatment with Reducing Agents . . . . . 223 Alfred Zweidler and Leonard H. Cohen Large-Scale Isolation and Fractionation of Organs of \bionameDrosophila Melanogaster Larvae . . . . . . . . . . 240 David D. Wood and David J. L. Luck A Paracrystalline Inclusion in Neurospora Crassa . . . . . . . . . . . 249 Garth L. Nicolson and V. T. Marchesi and S. J. Singer The Localization of Spectrin on the Inner Surface of Human Red Blood Cell Membranes by Ferritin-Conjugated Antibodies . . . . . . . . . . . . . . . 265 W. P. Cunningham and H. H. Mollenhauer and S. E. Nyquist Isolation of Germ Cell Golgi Apparatus from Seminiferous Tubules of Rat Testes 273 Ellen Roter Dirksen Centriole Morphogenesis in Developing Ciliated Epithelium of the Mouse Oviduct 286 Liane Beif-Lehrer Actinomycin-D Enhancement of Glutamine Synthetase Activity in Chick Embryo Retinas Cultured in the Presence of Cortisol . . . . . . . . . . . . . . . . 303 Dagmar Iványi Number and Size of Nucleoli in Binucleate Liver Cells . . . . . . . . . 313 Jane A. Westfall and S. Yamataka and Paul D. Enos Ultrastructural Evidence of Polarized Synapses in the Nerve Net of Hydra . . . 318 Peter A. Simpson and Allan D. Dingle Variable Periodicity in the Rhizoplast of Naegleria Flagellates . . . . . . . . 323 Stephen Gobel Axo-Axonic Septate Junctions in the Basket Formations of the Cat Cerebellar Cortex . . . . . . . . . . . . . . . . . 328 Jean A. Sage and Ralph A. Jersild Comparative Distribution of Carbohydrates and Lipid Droplets in the Golgi Apparatus of Intestinal Absorptive Cells . . . . . . . . . . . . . . . . . 333 Ned Feder Microperoxidase . . . . . . . . . . . . 339 G. C. Saunders and M. Wilder Repetitive Maturation Cycles in a Cultured Mouse Myeloma . . . . . . . . . 344 Matthew M. Lavail and Liane Reif-Lehrer Glutamine Synthetase in the Normal and Dystrophic Mouse Retina . . . . . . . . 348
U. Ringborg and L. Rydlander Nucleolar-Derived Ribonucleic Acid in Chromosomes, Nuclear Sap, and Cytoplasm of Chironomus Tentans Salivary Gland Cells . . . . . . . . . . . . . . . . . 355 A. R. Luff and H. L. Atwood Changes in the Sarcoplasmic Reticulum and Transverse Tubular System of Fast and Slow Skeletal Muscles of the Mouse During Postnatal Development . . . . . . 369 Robert A. Briggaman and Frederic G. Dalldorf and Clayton E. Wheeler Formation and Origin of Basal Lamina and Anchoring Fibrils in Adult Human Skin 384 Jacopo Meldolesi and Dario Cova In Vitro Stimulation of Enzyme Secretion and the Synthesis of Microsomal Membranes in the Pancreas of the Guinea Pig . . . . . . . . . . . . . . . . . . 396 Gerd G. Maul and Joseph W. Price and Michael W. Lieberman Formation and Distribution of Nuclear Pore Complexes in Interphase . . . . . . 405 John B. Richardson and Aur\`ele Beaulnes The Cellular Site of Action of Angiotensin . . . . . . . . . . . . . . 419 Linda W. Reynolds and Vernon M. Ingram Erythroid Cell Differentiation and the Inhibition of Cytokinesis by Cytochalasin . . . . . . . . . . . . . . 433 Helen K. Hagopian and Vernon M. Ingram Developmental Changes of Erythropoiesis in Cultured Chick Blastoderms . . . . . 440 E. M. Evans and J. M. Wrigglesworth and K. Burdett and W. F. R. Pover Studies on Epithelial Cells Isolated from Guinea Pig Small Intestine . . . . 452 Pál Röhlich and Per Anderson and Börje Uvnäs Electron Microscope Observations on Compound 48/$ 80$-Induced Degranulation in Rat Mast Cells . . . . . . . . . . . 465 Nicholas K. Gonatas and Lucila Autilio-Gambetti and Pierluigi Gambetti and Brenda Shafer Morphological and Biochemical Changes in Rat Synaptosome Fractions During Neonatal Development . . . . . . . . . . 484 Robert H. Holdsworth The Isolation and Partial Characterization of the Pyrenoid Protein of Eremosphaera Viridis . . . . . . . . 499 Gerald Soslau and Margit M. K. Nass Effects of Ethidium Bromide on the Cytochrome Content and Ultrastructure of L Cell Mitochondria . . . . . . . . . . 514 Stephen Roth and Edward J. McGuire and Saul Roseman An Assay for Intercellular Adhesive Specificity . . . . . . . . . . . . . . 525 Stephen Roth and Edward J. McGuire and Saul Roseman Evidence for Cell-Surface Glycosyltransferases . . . . . . . . . . 536 Peter R. Dallman Malnutrition: Incorporation of Thymidine-$^3$H into Nuclear and Mitochondrial DNA . . . . . . . . . . . 549 James B. Wade and Vincent A. Discala The Effect of Osmotic Flow on the Distribution of Horseradish Peroxidase Within the Intercellular Spaces of Toad Bladder Epithelium . . . . . . . . . . . 553 Gerd G. Maul On the Octagonality of the Nuclear Pore Complex . . . . . . . . . . . . . . . . 558 J. Zalta and J.-P. Zalta and R. Simard Isolation of Nucleoli . . . . . . . . . 563 B. D. Mulvaney Chemography of Lysosome-Like Structures in Olfactory Epithelium . . . . . . . . 568 Judy M. Strum Unusual Peroxidase-Positive Granules in the Developing Rat Submaxillary Gland 575 John F. Aronson Demonstration of a Colcemid-Sensitive Attractive Force Acting Between the Nucleus and a Center . . . . . . . . . . 579
David H. K. Chui and Meir Djaldetti and Paul A. Marks and Richard A. Rifkind Erythropoietin Effects on Fetal Mouse Erythroid Cells . . . . . . . . . . . . 585 K. Nakagami and H. Warshawsky and C. P. Leblond The Elaboration of Protein and Carbohydrate by Rat Parathyroid Cells As Revealed by Electron Microscope Radioautography . . . . . . . . . . . . 596 Stephen M. Shea Lanthanum Staining of the Surface Coat of Cells . . . . . . . . . . . . . . . . 611 Nobuhisa Baba and Hari M. Sharma Histochemistry of Lactic Dehydrogenase in Heart and Pectoralis Muscles of Rat 621 S. Granick and Donna Granick Nucleolar Necklaces in Chick Embryo Myoblasts Formed by Lack of Arginine . . 636 Roy S. Wu and Jonathan R. Warner Cytoplasmic Synthesis of Nuclear Proteins . . . . . . . . . . . . . . . . 643 J. R. Gautschi and R. Schindler and C. Hürni Studies on the Division Cycle of Mammalian Cells . . . . . . . . . . . . 653 Richard W. Hendler Respiration and Protein Synthesis in \bionameEscherichia coli Membrane-Envelope Fragments . . . . . . 664 R. W. Rowe Ultrastructure of the Z Line of Skeletal Muscle Fibers . . . . . . . . . . . . . 674 H. Rubin pH and population density in the regulation of animal cell multiplication 686 Virginia M. Tennyson and Miro Brzin and Paul Slotwiner The Appearance of Acetylcholinesterase in the Myotome of the Embryonic Rabbit 703 Andrew P. Somlyo and Carrick E. Devine and Avril V. Somlyo and Stanley R. North Sarcoplasmic Reticulum and the Temperature-Dependent Contraction of Smooth Muscle in Calcium-Free Solutions 722 Liselotte Mezger-Freed Puromycin Resistance in Haploid and Heteroploid Frog Cells: Gene Or Membrane Determined? . . . . . . . . . . . . . . 742 Robert D. Goldman The Role of Three Cytoplasmic Fibers in Bhk-21 Cell Motility . . . . . . . . . . 752 Richard H. Colby Intrinsic Birefringence of Glycerinated Myofibrils . . . . . . . . . . . . . . . 763 A. Kent Christensen Frozen Thin Sections of Fresh Tissue for Electron Microscopy, with a Description of Pancreas and Liver . . . . . . . . . 772 N. Scott McNutt and Robert A. Hershberg and Ronald S. Weinstein Further Observations on the Occurrence of Nexuses in Benign and Malignant Human Cervical Epithelium . . . . . . . . . . 805 Chandler Fulton and Allan D. Dingle Basal Bodies, But Not Centrioles, in Naegleria . . . . . . . . . . . . . . . 826 Lewis G. Tilney How Microtubule Patterns Are Generated 837 Christopher S. Potten Early and Late Incorporation of Tritiated Thymidine into Skin Cells and the Presence of a Long-Lived G$_0$-Specific Precursor Pool . . . . . 855 Christopher S. Potten and Jean C. Schaer Labeling of Murine Mastocytoma Cells in Vitro with Plasma Tritiated Thymidine-Labeled Animals . . . . . . . 862 Norton B. Gilula and Peter Satir Septate and Gap Junctions in Molluscan Gill Epithelium . . . . . . . . . . . . 869 Garry T. Cole and Henry C. Aldrich Demonstration of Myelin Figures in Unfixed, Freeze-Etched Fungus Spores . . 873 G. Bennett and C. P. Leblond Passage of Fucose-$^3$H Label from the Golgi Apparatus into Dense and Multivesicular Bodies in the Duodenal Columnar Cells and Hepatocytes of the Rat . . . . . . . . . . . . . . . . . . 875 Werner W. Franke and Jürgen Kartenbeck and Hanswalter Zentgraf and Ulrich Scheer and Heinz Falk Membrane-To-Membrane Cross-Bridges . . . 881 Carolyn M. Conway Evidence for RNA in the Heavy Bodies of Sea Urchin Eggs . . . . . . . . . . . . 889 Francis J. Chlapowski Regularly Arranged Particles on the Inner Lamella of the Plasma Membrane of \bionameAcanthamoeba Palestinensis . . . 893 Edward F. Haskins and A. Arlan Hinchee and Richard A. Cloney The Occurrence of Synaptonemal Complexes in the Slime Mold Echinostelium Minutum De Bary . . . . . . . . . . . . . . . . 898 George Gordon Brown and Walter J. Humphreys Sperm-Egg Interactions of Limulus Polyphemus with Scanning Electron Microscopy . . . . . . . . . . . . . . . 904
Allen W. Clark and William P. Hurlbut and Alexander Mauro Changes in the Fine Structure of the Neuromuscular Junction of the Frog Caused by Black Widow Spider Venom . . . 1 Harold I. Friedman and Robert R. Cardell Effects of Puromycin on the Structure of Rat Intestinal Epithelial Cells During Fat Absorption . . . . . . . . . . . . . 15 S. Schiaffino and V\vera Hanzlíková Autophagic Degradation of Glycogen in Skeletal Muscles of the Newborn Rat . . 41 Michael C. O'Neill and Frank E. Stockdale A Kinetic Analysis of Myogenesis in Vitro . . . . . . . . . . . . . . . . . 52 W. Gerald Robison Microtubular Patterns in Spermatozoa of Coccid Insects in Relation to Bending 66 J. Kenneth Hoober A Major Polypeptide of Chloroplast Membranes of Chlamydomonas Reinhardi . . 84 Tatsuro Ikeuchi and Herbert Weinfeld and Avery A. Sandberg Chromosome Pulverization in Micronuclei Induced by Tritiated Thymidine . . . . . 97 Peter H. Cooke and Fredric S. Fay Correlation Between Fiber Length, Ultrastructure, and the Length-Tension Relationship of Mammalian Smooth Muscle 105 James R. Stewart and Robert A. Weisman Exocytosis of Latex Beads During the Encystment of \bionameAcanthamoeba . . . 117 Peter G. W. Plagemann Nucleotide Pools in Novikoff Rat Hepatoma Cells Growing in Suspension Culture . . . . . . . . . . . . . . . . 131 M. F. Kramer and C. Poort Unstimulated Secretion of Protein from Rat Exocrine Pancreas Cells . . . . . . 147 Jean-Jacques Widmann and Ramzi S. Cotran and H. Dariush Fahimi Mononuclear Phagocytes (Kupffer Cells) and Endothelial Cells . . . . . . . . . 159 Arrigo Benedetto and Wiktor Djaczenko 37Rc Cells Rapidly Recover Their RNA Synthesis After Inhibition with High Doses of Actinomycin D . . . . . . . . . 171 P. G. Whitmore Isolation of Microfibrils from Rat Vibrissal Follicles . . . . . . . . . . 174 Ben Lung Ultrastructure and Chromatin Disaggregation of Human Sperm Head with Thioglycolate Treatment . . . . . . . . 179 Wiktor Djaczenko and Antonio Cassone Visualization of New Ultrastructural Components in the Cell Wall of Candida Albicans with Fixatives Containing Tapo 186 J. P. Tranzer and M. da Prada and A. Pletscher Storage of $5$-Hydroxytryptamine in Megakaryocytes . . . . . . . . . . . . . 191 Tsuranobu Shirahama and Alan S. Cohen The Role of Mucopolysaccharides in Vesicle Architecture and Endothelial Transport . . . . . . . . . . . . . . . 198 Nelly Auerspebg Microfilaments in Epithelial Morphogenesis . . . . . . . . . . . . . 206 Sandra K. Masur and Eric Holtzman and Roderich Walter Hormone-Stimulated Exocytosis in the Toad Urinary Bladder . . . . . . . . . . 211 Walter Rubin An Unusual Intimate Relationship Between Endocrine Cells and Other Types of Epithelial Cells in the Human Stomach 219
Colvin M. Redman and M. George Cherian The Secretory Pathways of Rat Serum Glycoproteins and Albumin . . . . . . . 231 Robert D. Goldman The Effects of Cytochalasin B on the Microfilaments of Baby Hamster Kidney (Bhk-21) Cells . . . . . . . . . . . . . 246 Frank A. Pepe and Barbara Drucker The Myosin Filament . . . . . . . . . . 255 Olga Greengard and Micheline Federman and W. Eugene Knox Cytomorphometry of Developing Rat Liver and Its Application to Enzymic Differentiation . . . . . . . . . . . . 261 Zane B. Carothers Studies of Spermatogenesis in the Hepaticae . . . . . . . . . . . . . . . 273 Joseph B. Warshaw and Miriam D. Rosenthal Changes in Glucose Oxidation During Growth of Embryonic Heart Cells in Culture . . . . . . . . . . . . . . . . 283 G. S. Stein and T. W. Borun The Synthesis of Acidic Chromosomal Proteins During the Cell Cycle of HeLa S-3 Cells . . . . . . . . . . . . . . . 292 T. W. Borun and G. S. Stein The Synthesis of Acidic Chromosomal Proteins During the Cell Cycle of HeLa S-3 Cells . . . . . . . . . . . . . . . 308 Elroy Cantrell and Edward Bresnick Benzpyrene Hydroxylase Activity in Isolated Parenchymal and Nonparenchymal Cells of Rat Liver . . . . . . . . . . . 316 Jack C. Vaughn and Lillian A. Thomson A Kinetic Study of DNA and Basic Protein Metabolism During Spermatogenesis in the Sand Crab, Emerita Analoga . . . . . . . 322 T. Morimoto and G. Blobel and D. D. Sabatini Ribosome Crystallization in Chicken Embryos . . . . . . . . . . . . . . . . 338 T. Morimoto and G. Blobel and D. D. Sabatini Ribosome Crystallization in Chicken Embryos . . . . . . . . . . . . . . . . 355 Wayne A. Busch and M. H. Stromer and Darrel E. Goll and A. Suzuki Ca$^{2+}$-specific removal of Z lines from rabbit skeletal muscle . . . . . . 367 William K. Ovalle Fine Structure of Rat Intrafusal Muscle Fibers . . . . . . . . . . . . . . . . . 382 Arthur R. Hand and Stephen Gobel The Structural Organization of the Septate and Gap Junctions of Hydra . . . 397 Philip J. Pawlowski and Maurice H. Vaughan Comparison of the Relative Synthesis of the Proteins of the 50 S Ribosomal Subunit in Growing and Valine-Deprived HeLa Cells . . . . . . . . . . . . . . . 409 L. R. Ganion and R. G. Kessel Intracellular Synthesis, Transport, and Packaging of Proteinaceous Yolk in Oocytes of Orconectes Immunis . . . . . 420 N. Kraft and Ken Shortman Differentiation of Antibody-Forming Cells in Toad Spleen . . . . . . . . . . 438 Arthur R. Ugel and William Idler Further Characterization of Bovine Keratohyalin . . . . . . . . . . . . . . 453 Bertram Sacktor and Yoshio Shimada Degenerative Changes in the Mitochondria of Flight Muscle from Aging Blowflies 465 Miklós Müller Secretion of Acid Hydrolases and Its Intracellular Source in \bionameTetrahymena Pyriformis . . . . . 478 Albert I. Farbman Differentiation of Taste Buds in Organ Culture . . . . . . . . . . . . . . . . 489 John D. Taylor and Mac E. Hadley The Fate of Amphibian Egg Melanosomes 493
Nagasumi Yago and Masatoshi Seki and Shigetaka Sekiyama and Shigeru Kobayashi and Hiromi Kurokawa and Yuko Iwai and Fumiaki Sato and Akihiro Shiragai Growth and Differentiation of Mitochondria in the Regenerating Rat Adrenal Cortex . . . . . . . . . . . . . 503 Peter J. Stambrook and Jesse E. Sisken Induced Changes in the Rates of Uridine-$^3$H Uptake and Incorporation During the G$_1$ and S Periods of Synchronized Chinese Hamster Cells . . . 514 P. Gambetti and L. A. Autilio-Gambetti and N. K. Gonatas and B. Shafer Protein Synthesis in Synaptosomal Fractions . . . . . . . . . . . . . . . 526 J. V. Simson and S. S. Spicer Ferritin Particles in Macrophages and in Associated Mast Cells . . . . . . . . . 536 Christopher C. Widnell Cytochemical Localization of 5'-Nucleotidase in Subcellular Fractions Isolated from Rat Liver . . . . . . . . 542 H. L. Leffert and D. Paul Studies on Primary Cultures of Differentiated Fetal Liver Cells . . . . 559 Lesley Watson Coggins and Joseph G. Gall The Timing of Meiosis and DNA Synthesis During Early Oogenesis in the Toad, \bionameXenopus Laevis . . . . . . . . . 569 Minnie Mathan and John A. Hermos and Jerry S. Trier Structural Features of the Epithelio-Mesenchymal Interface of Rat Duodenal Mucosa During Development . . . 577 Frank E. Stockdale and Michael C. O'neill Repair DNA Synthesis in Differentiated Embryonic Muscle Cells . . . . . . . . . 589 Heidi Smith-Johannsen and Sarah P. Gibbs Effects of Chloramphenicol on Chloroplast and Mitochondrial Ultrastructure in Ochromonas Danica . . 598 F. A. Rawlins and G. M. Villegas and E. T. Hedley-Whyte and B. G. Uzman Fine Structural Localization of Cholesterol-1,2-$^3$H in Degenerating and Regenerating Mouse Sciatic Nerve . . 615 Arieh Gilai and I. Parnas Electromechanical Coupling in Tubular Muscle Fibers . . . . . . . . . . . . . 626 David B. Dusenbery and Robert B. Uretz The Orientation of DNA Within $ 80$-Angstrom Chromatin Fibers . . . . . 639 Vivianne T. Nachmias Electron Microscope Observations on Myosin from \bionamePhysarum Polycephalum . . . . . . . . . . . . . . 648 Merton R. Bernfield and Shib D. Banerjee Acid Mucopolysaccharide (Glycosaminoglycan) at the Epithelial-Mesenchymal Interface of Mouse Embryo Salivary Glands . . . . . . 664 Merton R. Bernfield and Shib D. Banerjee and Ronald H. Cohn Dependence of Salivary Epithelial Morphology and Branching Morphogenesis Upon Acid Mucopolysaccharide-Protein (Proteoglycan) at the Epithelial Surface 674 Carrick E. Devine and Avril V. Somlyo and Andrew P. Somlyo Sarcoplasmic Reticulum and Excitation-Contraction Coupling in Mammalian Smooth Muscles . . . . . . . . 690 Thomas L. Lentz Distribution of Leucine-$^3$H During Axoplasmic Transport Within Regenerating Neurons As Determined by Electron-Microscope Radioautography . . 719 Owen Black and Edward Bresnick Ontogenetic Changes of Proteins of Endoplasmic Reticulum . . . . . . . . . 733 M. K. Raizada and C. R. Krishna Murti Transformation of Trophic Hartmannella Culbertsoni into Viable Cysts by Cyclic 3',5'-Adenosine Monophosphate . . . . . 743 Samuel Dales Concerning the Universality of a Microtubule Antigen in Animal Cells . . 748 Joseph McGuire and Gisela Moellmann and Frank McKeon Cytochalasin B and Pigment Granule Translocation . . . . . . . . . . . . . 754
R. Scharff and R. W. Hendler and N. Nanninga and A. H. Burgess Respiration and Protein Synthesis in \bionameEscherichia coli Membrane-Envelope Fragments . . . . . . 1 Donald L. Price and Keith R. Porter The Response of Ventral Horn Neurons to Axonal Transection . . . . . . . . . . . 24 Susannah T. Rohrlich and Keith R. Porter Fine Structural Observations Relating to the Production of Color by the Iridophores of a Lizard, Anolis Carolinensis . . . . . . . . . . . . . . 38 Ernest W. April and Philip W. Brandt and Gerald F. Elliott The Myofilament Lattice: Studies on Isolated Fibers . . . . . . . . . . . . 53 W. E. Cassady and E. H. Leiter and A. Bergquist and R. P. Wagner Separation of Mitochondrial Membranes of Neurospora Crassa . . . . . . . . . . . 66 L. Andrew Staehelin and Francis J. Chlapowski and Mary A. Bonneville Lumenal Plasma Membrane of the Urinary Bladder . . . . . . . . . . . . . . . . 73 Francis J. Chlapowski and Mary A. Bonneville and L. Andrew Staehelin Lumenal Plasma Membrane of the Urinary Bladder . . . . . . . . . . . . . . . . 92 Donald J. Cummings Isolation and Partial Characterization of Macro- and Micronuclei from Paramecium Aurelia . . . . . . . . . . . 105 Helmut Plattner and Walter M. Fischer and Werner W. Schmitt and Luis Bachmann Freeze Etching of Cells Without Cryoprotectants . . . . . . . . . . . . 116 Mary E. King and Gabriel C. Godman and Donald W. King Respiratory Enzymes and Mitochondrial Morphology of HeLa and L Cells Treated with Chloramphenicol and Ethidium Bromide . . . . . . . . . . . . . . . . 127 Brian E. Gilbert and Terry C. Johnson Protein Turnover During Maturation of Mouse Brain Tissue . . . . . . . . . . . 143 Daniel S. Friend and Norton B. Gilula A Distinctive Cell Contact in the Rat Adrenal Cortex . . . . . . . . . . . . . 148 Mathew P. Daniels Colchicine Inhibition of Nerve Fiber Formation in Vitro . . . . . . . . . . . 164 George L. Eliceiri The Ribosomal RNA of Hamster-Mouse Hybrid Cells . . . . . . . . . . . . . . 177 Matthew M. LaVail and Richard L. Sidman and Deborah O'Neil Photoreceptor-Pigment Epithelial Cell Relationships in Rats with Inherited Retinal Degeneration . . . . . . . . . . 185 S. G. Waxman and G. D. Pappas and M. V. L. Bennett Morphological Correlates of Functional Differentiation of Nodes of Ranvier Along Single Fibers in the Neurogenic Electric Organ of the Knife Fish Sternarchus . . . . . . . . . . . . . . 210 A. F. Hopper and P. M. Rose and R. W. Wannemacher Cell Population Changes in the Intestinal Mucosa of Protein-Depleted Or Starved Rats . . . . . . . . . . . . . . 225 C. A. Pasternak Relief from Contact Inhibition . . . . . 231 Camillo Peracchia and Brant S. Mittler Fixation by Means of Glutaraldehyde-Hydrogen Peroxide Reaction Products . . . . . . . . . . . 234 A. L. Kierszenbaum and Laura L. Tres and C. J. Tandler The Distribution of Inorganic Cations During Spermiogenesis in the Mouse . . . 239 Richard F. Baker Fusion of Human Red Blood Cell Membranes 244 C. Meban Localization of Phosphatidic Acid Phosphatase Activity in Granular Pneumonocytes . . . . . . . . . . . . . 249 Martin Hagopian and Eladio A. Nunez Sarcolemmal Scalloping at Short Sarcomere Lengths with Incidental Observations on the T Tubules . . . . . 252 Robert E. Hinkley and Frederick E. Samson Anesthetic-Induced Transformation of Axonal Microtubules . . . . . . . . . . 258 F. Rudolf Turner Modified Microtubules in the Testis of the Water Strider, Gerris Remigis (Say) 263
Constantino Sotelo and Rodolfo Llinás Specialized Membrane Junctions Between Neurons in the Vertebrate Cerebellar Cortex . . . . . . . . . . . . . . . . . 271 J. David Castle and James D. Jamieson and George E. Palade Radioautographic Analysis of the Secretory Process in the Parotid Acinar Cell of the Rabbit . . . . . . . . . . . 290 Phyllis R. Strauss Acriflavin Resistance in the Hemoflagellate, Leishmania Tarentolae 312 H. J. Mersmann and J. Goodman and J. M. Houk and S. Anderson Studies on the Biochemistry of Mitochondria and Cell Morphology in the Neonatal Swine Hepatocyte . . . . . . . 335 Bruce H. Lipton and Irwin R. Konigsberg A Fine-Structural Analysis of the Fusion of Myogenic Cells . . . . . . . . . . . 348 Nicolae Simionescu and Maia Simionescu and George E. Palade Permeability of Intestinal Capillaries 365 David R. Wolstenholme and Robert G. Kirschner and Nicholas J. Gross Heat Denaturation Studies of Rat Liver Mitochondrial DNA . . . . . . . . . . . 393 B. Lambert and L. Wieslander and B. Daneholt and E. Egyházi and U. Ringborg In Situ Demonstration of DNA Hybridizing with Chromosomal and Nuclear Sap RNA in Chironomus Tentans . . . . . . . . . . . 407 Thomas E. Schroeder The Contractile Ring . . . . . . . . . . 419 Irving Goldschneider and A. A. Moscona Tissue-Specific Cell-Surface Antigens in Embryonic Cells . . . . . . . . . . . . 435 Charles R. Hackenbrock Energy-Linked Ultrastructural Transformations in Isolated Liver Mitochondria and Mitoplasts . . . . . . 450 Steven A. Rosenberg and Albert B. Einstein Sialic Acids on the Plasma Membrane of Cultured Human Lymphoid Cells . . . . . 466 Bruce P. Brandhorst and Tom Humphreys Stabilities of Nuclear and Messenger RNA Molecules in Sea Urchin Embryos . . . . 474 Laura L. Tres and A. L. Kierszenbaum and C. J. Tandler Inorganic Cations in the Cell Nucleus 483 Norton B. Gilula and Peter Satir The Ciliary Necklace . . . . . . . . . . 494 Lynette Feeney and Steven L. Wissig A Biochemical and Radioautographic Analysis of Protein Secretion by Thyroid Lobes Incubated in Vitro . . . . . . . . 510 E. Egyházi and B. D'Monte and J.-E. Edström Effects of $ \alpha $-amanitin on in vitro labeling of RNA from defined nuclear components in salivary gland cells from \bionameChironomus tentans 523 Phyllis M. Novikoff and Alex B. Novikoff Peroxisomes in Absorptive Cells of Mammalian Small Intestine . . . . . . . 532 David M. Phillips Comparative Analysis of Mammalian Sperm Motility . . . . . . . . . . . . . . . . 561 G. T. O'Loughlin and T. C. Chambers Extracellular Microtubules in the Aphid Gut . . . . . . . . . . . . . . . . . . 575 P. F. Baker and Anne E. Warner Intracellular Calcium and Cell Cleavage in Early Embryos of \bionameXenopus Laevis . . . . . . . . . . . . . . . . . 579 S. S. Spicer and B. J. Martin and J. V. Simson The Junctional Complex Associated Body of Human Eccrine Sweat Gland . . . . . . 582 Joshua R. Sanes and Lawrence M. Okun Induction of DNA Synthesis in Cultured Neurons by Ultraviolet Light Or Methyl Methane Sulfonate . . . . . . . . . . . 587 Thomas W. O'Brien Occurrence of Active 80 S Ribosomes in Subcellular Particles in the Mitochondrial Fraction of Fetal Bovine Liver . . . . . . . . . . . . . . . . . 590 Jerry E. Manning and David R. Wolstenholme and Oliver C. Richards Circular DNA Molecules Associated with Chloroplasts of Spinach, Spinacia Oleracea . . . . . . . . . . . . . . . . 594 Thomas S. Lecount and Robert D. Grey Transient Shortening of Microvilli Induced by Cycloheximide in the Duodenal Epithelium of the Chicken . . . . . . . 601 James N. Dumont and R. A. Wallace The Effects of Vinblastine on Isolated \bionameXenopus Oocytes . . . . . . . . 605
Stephanie Gordon Phillips Repopulation of the Postmitotic Nucleolus by Preformed RNA . . . . . . . 611 William R. Jeffery Evidence for a Temporal Incompatibility Between DNA Replication and Division During the Cell Cycle of \bionameTetrahymena . . . . . . . . . . 624 Beatriz G. T. Pogo Early Events in Lymphocyte Transformation by Phytohemagglutinin . . 635 C. R. Hopkins The Biosynthesis, Intracellular Transport, and Packaging of Melanocyte-Stimulating Peptides in the Amphibian Pars Intermedia . . . . . . . 642 Fritz A. Henn and Hans-Arne Hansson and Anders Hamberger Preparation of Plasma Membrane from Isolated Neurons . . . . . . . . . . . . 654 V. Herzog and F. Miller The Localization of Endogenous Peroxidase in the Lacrimal Gland of the Rat During Postnatal Development . . . . 662 Blair Bowers and Thomas E. Olszewski Pinocytosis in \bionameAcanthamoeba Castellanii . . . . . . . . . . . . . . 681 Gary G. Leppard and J. Ross Colvin Electron-Opaque Fibrils and Granules in and Between the Cell Walls of Higher Plants . . . . . . . . . . . . . . . . . 695 Charles E. Stirling Radioautographic Localization of Sodium Pump Sites in Rabbit Intestine . . . . . 704 Donald E. Olins and Ada L. Olins Physical Studies of Isolated Eucaryotic Nuclei . . . . . . . . . . . . . . . . . 715 Eugene A. Arnold and David H. Yawn and David G. Brown and Robert C. Wyllie and Donald S. Coffey Structural Alteration in Isolated Rat Liver Nuclei After Removal of Template Restriction by Polyanions . . . . . . . 737 Daniel S. Friend and Norton B. Gilula Variations in Tight and Gap Junctions in Mammalian Tissues . . . . . . . . . . . 758 Pedro Pinto da Silva Translational Mobility of the Membrane Intercalated Particles of Human Erythrocyte Ghosts . . . . . . . . . . . 777 Daniel G. Wright and Stephen E. Malawista The Mobilization and Extracellular Release of Granular Enzymes from Human Leukocytes During Phagocytosis . . . . . 788 Roch Bernier and Roberto Iglesias and René Simard Detection of DNA by Tritiated Actinomycin D on Ultrathin Frozen Sections . . . . . . . . . . . . . . . . 798 P. S. Vassar and J. M. Hards and D. E. Brooks and B. Hagenberger and G. V. F. Seaman Physicochemical Effects of Aldehydes on the Human Erythrocyte . . . . . . . . . 809 D. Montgomery Bissell and Jeremiah G. Tilles Radioimmunoassay of Serum Albumin Produced by Human Embryonic Liver in Monolayer Culture . . . . . . . . . . . 819 Werner W. Franke and Ulrich Scheer and Hansjörg Fritsch Intranuclear and Cytoplasmic Annulate Lamellae in Plant Cells . . . . . . . . 823 Tom Brady and Mary E. Clutter Cytolocalization of Ribosomal Cistrons in Plant Polytene Chromosomes . . . . . 827 Milan Potmesil and Anna Goldfeder Nucleolar Morphology and Maturation of Thymic Lymphocytes . . . . . . . . . . . 832 Joan B. Peterson and Robert H. Gray and Hans Ris Meiotic Spindle Plaques in \bionameSaccharomyces Cerevisiae . . . . 837 Harold C. Slavkin and Richard Croissant and Pablo Bringas Epithelial-Mesenchymal Interactions During Odontogenesis . . . . . . . . . . 841 Yasuo Uehara and Geoffrey Burnstock Postsynaptic Specialization of Smooth Muscle at Close Neuromuscular Junctions in the Guinea Pig Sphincter Pupillae . . 849 Taisuke Nakao Fusion of Unit Membranes of the Endoplasmic Reticulum in the Gill Epithelial Cell of Shrimp, Caridina . . 853
Ronald H. Stevens and Harold Amos RNA Metabolism in HeLa Cells at Reduced Temperature . . . . . . . . . . . . . . 1 A. Adoutte and M. Balmefrézol and J. Beisson and J. André The Effects of Erythromycin and Chloramphenicol on the Ultrastructure of Mitochondria in Sensitive and Resistant Strains of Paramecium . . . . . . . . . 8 J. B. Rattner Observations of Centriole Formation in Male Meiosis . . . . . . . . . . . . . . 20 B. Ceccarelli and W. P. Hurlbut and A. Mauro Depletion of Vesicles from Frog Neuromuscular Junctions by Prolonged Tetanic Stimulation . . . . . . . . . . 30 Sidney L. Tamm Free Kinetosomes in Australian Flagellates . . . . . . . . . . . . . . 39 Paul M. Lizardi and David J. L. Luck The Intracellular Site of Synthesis of Mitochondrial Ribosomal Proteins in Neurospora Crassa . . . . . . . . . . . 56 Barbara H. Gibbons and I. R. Gibbons Flagellar Movement and Adenosine Triphosphatase Activity in Sea Urchin Sperm Extracted with Triton X-100 . . . 75 Helen K. Hagopian and Judith A. Lippke and Vernon M. Ingram Erythropoietic Cell Cultures from Chick Embryos . . . . . . . . . . . . . . . . 98 D. Montgomery Bissell and Lydia Hammaker and Rudi Schmid Liver Sinusoidal Cells . . . . . . . . . 107 Sei-Ichi Matsui and Hiroshi Yoshida and Herbert Weinfeld and Avery A. Sandberg Induction of Prophase in Interphase Nuclei by Fusion with Metaphase Cells 120 Ralph Nachman and James G. Hirsch and Marco Baggiolini Studies on Isolated Membranes of Azurophil and Specific Granules from Rabbit Polymorphonuclear Leukocytes . . 133 Marilyn G. Farquhar and Dorothy F. Bainton and Marco Baggiolini and Christian de Duve Cytochemical Localization of Acid Phosphatase Activity in Granule Fractions from Rabbit Polymorphonuclear Leukocytes . . . . . . . . . . . . . . . 141 John A. Williams and J. Wolff Colchicine-Binding Protein and the Secretion of Thyroid Hormone . . . . . . 157 Mark Nameroff Contact-Mediated Reversible Suppression of Myogenesis . . . . . . . . . . . . . 166 Richard G. Kulka and Gordon M. Tomkins and Richard B. Crook Clonal Differences in Glutamine Synthetase Activity of Hepatoma Cells 175 Earl Ettienne Subcellular Localization of Calcium Repositories in Plasmodia of the Acellular Slime Mold \bionamePhysarum Polycephalum . . . . . . . . . . . . . . 179 Susan Drury Waaland and J. Robert Waaland and Robert Cleland A New Pattern of Plant Cell Elongation: Bipolar Band Growth . . . . . . . . . . 184 D. K. Jasper and J. R. Bronk Polar Distribution of Intramitochondrial Granules of Mucosal Epithelial Cells . . 190
W. A. Walker and R. Cornell and L. M. Davenport and K. J. Isselbacher Macromolecular Absorption . . . . . . . 195 Jean-Claude Wanson and Pierre Drochmans Role of the Sarcoplasmic Reticulum in Glycogen Metabolism . . . . . . . . . . 206 Dominic M. K. Lam The Biosynthesis and Content of Gamma-Aminobutyric Acid in the Goldfish Retina . . . . . . . . . . . . . . . . . 225 Hans-G Heidrich and Rolf Kinne and Eva Kinne-Saffran and Kurt Hannig The Polarity of the Proximal Tubule Cell in Rat Kidney . . . . . . . . . . . . . 232 Richard G. W. Anderson The Three-Dimensional Structure of the Basal Body from the Rhesus Monkey Oviduct . . . . . . . . . . . . . . . . 246 Richard C. Weisenberg Changes in the Organization of Tubulin During Meiosis in the Eggs of the Surf Clam, Spisula Solidissima . . . . . . . 266 David C. Shephard and Wendy B. Levin Biosynthesis in Isolated Acetabularia Chloroplasts . . . . . . . . . . . . . . 279 R. Tanguay and K. D. Chaudhary Studies on Mitochondria . . . . . . . . 295 Terry E. Machen and David Erlij and F. B. P. Wooding Permeable Junctional Complexes . . . . . 302 E. Gantt and C. A. Lipschultz Phycobilisomes of Porphyridium Cruentum 313 Adrian R. L. Gear and Jana M. Bednarek Direct Counting and Sizing of Mitochondria in Solution . . . . . . . . 325 Hartmut C. Renger and David R. Wolstenholme The Form and Structure of Kinetoplast DNA of Crithidia . . . . . . . . . . . . 346 I. R. Gibbons and E. Fronk Some Properties of Bound and Soluble Dynein from Sea Urchin Sperm Flagella 365 James E. Bourdeau and Frank A. Carone and Charles E. Ganote Serum Albumin Uptake in Isolated Perfused Renal Tubules . . . . . . . . . 382 J. Ramus and S. T. Groves Incorporation of Sulfate into the Capsular Polysaccharide of the Red Alga Porphyridium . . . . . . . . . . . . . . 399 Tito Cavallo and Robert Sade and Judah Folkman and Ramzi S. Cotran Tumor Angiogenesis . . . . . . . . . . . 408 A. G. Gambarini and R. Meneghini Ribosomal RNA Genes in Salivary Gland and Ovary of Rhynchosciara Angelae . . . 421 Robert J. Chertok and Suzanne Lake A Simple Method for the Preparation of Renal Brush Borders . . . . . . . . . . 426 Kenneth D. Stewart and Gary L. Floyd and Karl R. Mattox and Melanie E. Davis Cytochemical Demonstration of a Single Peroxisome in a Filamentous Green Alga 431 Roger F. Searle Observations on the Unusual Cytoplasmic Lacunae of the Porcine Hepatocyte . . . 434
G. A. Langer and J. S. Frank Lanthanum in Heart Cell Culture . . . . 441 Judy M. Strum and Alain F. Junod Radioautographic Demonstration of $5$-Hydroxytryptamine-$^3$H Uptake by Pulmonary Endothelial Cells . . . . . . 456 Pierre V. Vignais and Barbara J. Stevens and Janine Huet and Jean André Mitoribosomes from Candida Utilis . . . 468 Edward Aiello and Michael A. Sleigh The Metachronal Wave of Lateral Cilia of Mytilus Edulis . . . . . . . . . . . . . 493 G. B. Witman and K. Carlson and J. Berliner and Joel L. Rosenbaum Chlamydomonas Flagella . . . . . . . . . 507 G. B. Witman and K. Carlson and Joel L. Rosenbaum Chlamydomonas Flagella . . . . . . . . . 540 N. Umiel and W. Plaut Interaction of Poly-L-Lysine with Chromatin . . . . . . . . . . . . . . . 556 Jack Rosenbluth Myoneural Junctions of Two Ultrastructurally Distinct Types in Earthworm Body Wall Muscle . . . . . . . 566 Giuseppina Barsacchi and Joseph G. Gall Chromosomal Localization of Repetitive DNA in the Newt, Triturus . . . . . . . 580 David C. Swinton and Philip C. Hanawalt In Vivo Specific Labeling of Chlamydomonas Chloroplast DNA . . . . . 592 Jerry W. Shay Electron Microscope Studies of Spermatozoa of Rhynchosciara Sp . . . . 598 Samuel B. Horowitz The Permeability of the Amphibian Oocyte Nucleus, in Situ . . . . . . . . . . . . 609 Tom Elsdale and Jonathan Bard Collagen Substrata for Studies on Cell Behavior . . . . . . . . . . . . . . . . 626 Robert A. Tobey and Harry A. Crissman and Paul M. Kraemer A Method for Comparing Effects of Different Synchronizing Protocols on Mammalian Cell Cycle Traverse . . . . . 638 Daniel A. Goodenough and Walther Stoeckenius The Isolation of Mouse Hepatocyte Gap Junctions . . . . . . . . . . . . . . . 646 Awtar Krishan Cytochalasin-B: Time-Lapse Cinematographic Studies on Its Effects on Cytokinesis . . . . . . . . . . . . . 657 H. Ono and S. Kobayashi and K. Yanagisawa Cell Fusion in the Cellular Slime Mold, \bionameDictyostelium Discoideum . . . . 665
Jacopo Meldolesi and Dario Cova Composition of Cellular Membranes in the Pancreas of the Guinea Pig . . . . . . . 1 Jeffrey E. Froehlich and Martin Rachmeler Effect of Adenosine 3'-5'-Cyclic Monophosphate on Cell Proliferation . . 19 Leonard Mindich and Samuel Dales Membrane Synthesis in Bacillus Subtilis 32 Asish C. Nag Ultrastructure and Adenosine Triphosphatase Activity of Red and White Muscle Fibers of the Caudal Region of a Fish, Salmo Gairdneri . . . . . . . . . 42 James L. Oschman and Betty J. Wall Calcium Binding to Intestinal Membranes 58 Brian L. Kotzin and Robert F. Baker Selective Inhibition of Genetic Transcription in Sea Urchin Embryos . . 74 Joram Piatigorsky and Henry deF. Webster and Miriam Wollberg Cell Elongation in the Cultured Embryonic Chick Lens Epithelium with and Without Protein Synthesis . . . . . . . 82 Thomas L. Lentz Development of the Neuromuscular Junction . . . . . . . . . . . . . . . . 93 Ariane Monneron and Günter Blobel and George E. Palade Fractionation of the Nucleus by Divalent Cations . . . . . . . . . . . . . . . . 104 Maria C. Magalhães A New Crystal-Containing Cell in Human Adrenal Cortex . . . . . . . . . . . . . 126 Sara E. Zalik and Vi Scott Cell Surface Changes During Dedifferentiation in the Metaplastic Transformation of Iris into Lens . . . . 134 H. Bruce Bosmann and Marjorie W. Myers and Delena Dehond and Richard Ball and Kenneth R. Case Mitochondrial Autonomy . . . . . . . . . 147 Peter G. W. Plagemann and John Erbe Thymidine Transport by Cultured Novikoff Hepatoma Cells and Uptake by Simple Diffusion and Relationship to Incorporation into Deoxyribonucleic Acid 161 Peter G. W. Plagemann and Richard D. Estensen Cytochalasin B . . . . . . . . . . . . . 179 Ralph M. Steinman and Zanvil A. Cohn The Interaction of Soluble Horseradish Peroxidase with Mouse Peritoneal Macrophages in Vitro . . . . . . . . . . 186 Dale Purves and Uel J. McMahan The Distribution of Synapses on a Physiologically Identified Motor Neuron in the Central Nervous System of the Leech . . . . . . . . . . . . . . . . . 205 Rhea J. C. Levine and Maynard M. Dewey and George W. de Villafranca Immunohistochemical Localization of Contractile Proteins in Limulus Striated Muscle . . . . . . . . . . . . . . . . . 221 Raymond J. Lasek and Carolyn K. Lee and Ronald J. Przybylski Granular Extensions of the Nucleoli in Giant Neurons of \bionameAplysia Californica . . . . . . . . . . . . . . 237 David A. Warner and James F. Perdue Cytochalasin B and the Adenosine Triphosphate Content of Treated Fibroblasts . . . . . . . . . . . . . . 242 Lelio Orci and Alain Perrelet and Arthur A. Like Fenestrae in the Rough Endoplasmic Reticulum of the Exocrine Pancreatic Cells . . . . . . . . . . . . . . . . . 245 Sidney L. Tamm Ciliary Motion in Paramecium . . . . . . 250
Hans J. Leenders and Pieter J. A. Beckers The Effect of Changes in the Respiratory Metabolism Upon Genome Activity . . . . 257 Richard W. Hendler and Amelia H. Burgess Respiration and Protein Synthesis in \bionameEscherichia coli Membrane-Envelope Fragments . . . . . . 266 Joan A. Higgins and Russell J. Barrnett Studies on the Biogenesis of Smooth Endoplasmic Reticulum Membranes in Livers of Phenobarbital-Treated Rats . . 282 Stanley G. Sawicki and Gabriel C. Godman On the Recovery of Transcription After Inhibition by Actinomycin D . . . . . . 299 Mac Donald Cave Localization of Ribosomal DNA Within Oocytes of the House Cricket, Acheta Domesticus (Orthoptera: Gryllidae) . . . 310 Thoru Pederson and Elliott Robbins Chromatin Structure and the Cell Division Cycle . . . . . . . . . . . . . 322 Wayne Hohman and Harald Schraer Low Temperature Ultramicroincineration of Thin-Sectioned Tissue . . . . . . . . 328 James E. Haber and John G. Peloquin and Harlyn O. Halvorson and Gary G. Borisy Colcemid Inhibition of Cell Growth and the Characterization of a Colcemid-Binding Activity in \bionameSaccharomyces Cerevisiae . . . . 355 James R. Aist and P. H. Williams Ultrastructure and Time Course of Mitosis in the Fungus Fusarium Oxysporum 368 Ann L. Hubbard and Zanvil A. Cohn The Enzymatic Iodination of the Red Cell Membrane . . . . . . . . . . . . . . . . 390 Rudolf Vracko and Earl P. Benditt Basal Lamina: the Scaffold for Orderly Cell Replacement . . . . . . . . . . . . 406 Anita C. Been and Ellen M. Rasch Cellular and Secretory Proteins of the Salivary Glands of Sciara Coprophila During the Larval-Pupal Transformation 420 Gerd G. Maul and Helmut M. Maul and Joseph E. Scogna and Michael W. Lieberman and Gary S. Stein and Betty Yee-Li Hsu and Thaddeus W. Borun Time Sequence of Nuclear Pore Formation in Phytohemagglutinin-Stimulated Lymphocytes and in HeLa Cells During the Cell Cycle . . . . . . . . . . . . . . . 433 Brian Burchell and Geoffrey J. Dutton and Andrew M. Nemeth Development of Phenobarbital-Sensitive Control Mechanisms for Uridine Diphosphate Glucuronyltransferase Activity in Chick Embryo Liver . . . . . 448 Nicholas E. Weber Ultrastructural Studies of Beef Heart Mitochondria . . . . . . . . . . . . . . 457 Jeanine-Anne Heuson-Stiennon and Jean-Claude Wanson and Pierre Drochmans Isolation and Characterization of the Sarcoplasmic Reticulum of Skeletal Muscle . . . . . . . . . . . . . . . . . 471 James Bearden and Irwin J. Bendet Birefringence of Spermatozoa . . . . . . 489 Irwin J. Bendet and James Bearden Birefringence of Spermatozoa . . . . . . 501 Frederick B. Merk and N. Scott McNutt Nexus Junctions Between Dividing and Interphase Granulosa Cells of the Rat Ovary . . . . . . . . . . . . . . . . . 511 Beatriz G. T. Pogo Specific Inhibition by Rifampicin of Transcription in Human Lymphocytes Stimulated by Phytohemagglutinin . . . . 515 S. Bullivant and D. G. Rayns and W. S. Bertaud and J. P. Chalcroft and G. F. Grayston Freeze-Fractured Myosin Filaments . . . 520 J. M. Sturgess and F. A. de la Iglesia Morphometry of the Golgi Apparatus in Developing Liver . . . . . . . . . . . . 524 G. Tripodi and P. Pizzolongo and M. Giannattasio A DNase-Sensitive Twisted Structure in the Mitochondrial Matrix of \bionamePolysiphonia (Rhodophyta) . . . 530
Bela J. Gulyas The Rabbit Zygote . . . . . . . . . . . 533 Peter B. Armstrong and David Parenti Cell Sorting in the Presence of Cytochalasin B . . . . . . . . . . . . . 542 Anna M. Novi and Renato Baserga Changes in Chromatin Template Activity and Their Relationship to DNA Synthesis in Mouse Parotid Glands Stimulated by Isoproterenol . . . . . . . . . . . . . 554 Joyce E. Purdy and Melvyn Lieberman and Anne E. Roggeveen and R. Gary Kirk Synthetic Strands of Cardiac Muscle . . 563 David A. Wolff and HÅkan Pertoft Separation of HeLa Cells by Colloidal Silica Density Gradient Centrifugation 579 F. Sreter and S. Holtzer and J. Gergely and H. Holtzer Some Properties of Embryonic Myosin . . 586 Alain Perrelet Protein Synthesis in the Visual Cells of the Honeybee Drone As Studied with Electron Microscope Radioautography . . 595 Malcolm S. Steinberg and Lawrence L. Wiseman Do Morphogenetic Tissue Rearrangements Require Active Cell Movements? . . . . . 606 Ralph M. Steinman and Zanvil A. Cohn The Interaction of Particulate Horseradish Peroxidase (Hrp)-Anti Hrp Immune Complexes with Mouse Peritoneal Macrophages in Vitro . . . . . . . . . . 616 Daniel V. Kimberg and John N. Loeb Effects of Cortisone Administration on Rat Liver Mitochondria . . . . . . . . . 635 Alan E. Organ and Eugene C. Bovee and Theodore L. Jahn The Mechanism of the Water Expulsion Vesicle of the Ciliate \bionameTetrahymena Pyriformis . . . . . 644 M. Paul and M. R. Goldsmith and J. R. Hunsley and F. C. Kafatos Specific Protein Synthesis in Cellular Differentiation . . . . . . . . . . . . 653 Barbra L. Eaton and Frank A. Pepe M Band Protein . . . . . . . . . . . . . 681 Carl W. Cotman and Dwan Taylor Isolation and Structural Studies on Synaptic Complexes from Rat Brain . . . 696 Paul M. Kraemer and Robert A. Tobey Cell-Cycle Dependent Desquamation of Heparan Sulfate from the Cell Surface 713 Roy Peach Nematosomes in the Rat Trigeminal Ganglion . . . . . . . . . . . . . . . . 718 Kenneth Watson The Organization of Ribosomal Granules Within Mitochondrial Structures of Aerobic and Anaerobic Cells of \bionameSaccharomyces Cerevisiae . . . . 721
J. Kenneth Hoober and William J. Stegeman Control of the Synthesis of a Major Polypeptide of Chloroplast Membranes in Chlamydomonas Reinhardi . . . . . . . . 1 Mark S. Mooseker and Lewis G. Tilney Isolation and Reactivation of the Axostyle . . . . . . . . . . . . . . . . 13 Ronald R. Minor Somite Chondrogenesis . . . . . . . . . 27 Clinton D. Stoner and Howard D. Sirak Adenine Nucleotide-Induced Contraction of the Inner Mitochondrial Membrane . . 51 Clinton D. Stoner and Howard D. Sirak Adenine Nucleotide-Induced Contraction of the Inner Mitochondrial Membrane . . 65 Graham Hoyle and Patricia A. McNeill and Allen I. Selverston Ultrastructure of Barnacle Giant Muscle Fibers . . . . . . . . . . . . . . . . . 74 Guido Zampighi and J. David Robertson Fine Structure of the Synaptic Discs Separated from the Goldfish Medulla Oblongata . . . . . . . . . . . . . . . 92 Donald Orlic and Robert Lev Fetal Rat Intestinal Absorption of Horseradish Peroxidase from Swallowed Amniotic Fluid . . . . . . . . . . . . . 106 Clara Franzini-Armstrong Studies of the Triad . . . . . . . . . . 120 Gary E. Wise and Lester Goldstein Electron Microscope Localization of Nuclear RNA's That Shuttle Between Cytoplasm and Nucleus and Nuclear RNA's That Do Not . . . . . . . . . . . . . . 129 N. Umiel and W. Plaut Interaction of Poly-L-Lysine with Chromatin . . . . . . . . . . . . . . . 139 Alberto J. Solari and Montrose J. Moses The Structure of the Central Region in the Synaptonemal Complexes of Hamster and Cricket Spermatocytes . . . . . . . 145 Birgit Satir and Caroline Schooley and Peter Satir Membrane Fusion in a Model System . . . 153 U. Oron and A. Bdolah Regulation of Protein Synthesis in the Venom Gland of Viperid Snakes . . . . . 177 M. R. Adelman and Gunter Blobel and David D. Sabatini An Improved Cell Fractionation Procedure for the Preparation of Rat Liver Membrane-Bound Ribosomes . . . . . . . . 191 M. R. Adelman and David D. Sabatini and Günter Blobel Ribosome-Membrane Interaction . . . . . 206 David R. Wolstenholme and Katsuro Koike and Patricia Cochran-Fouts Single Strand-Containing Replicating Molecules of Circular Mitochondrial DNA 230 David R. Wolstenholme and John D. McLaren and Katsuro Koike and Elaine L. Jacobson Catenated Oligomeric Circular DNA Molecules from Mitochondria of Malignant and Normal Mouse and Rat Tissues . . . . 247 Howard G. Sachs and Terence F. McDonald and Robert L. DeHaan Tetrodotoxin Sensitivity of Cultured Embryonic Heart Cells Depends on Cell Interactions . . . . . . . . . . . . . . 255 Gail Stetten and Seymour Lederberg Colcemid Sensitivity of Fission Yeast 259 Tomasz J. Wodzicki and Walter J. Humphreys Maturing Pine Tracheids . . . . . . . . 263 Bernard Tandler and Charles L. Hoppel Division of Giant Mitochondria During Recovery from Cuprizone Intoxication . . 266
Joseph W. DePierre and Manfred L. Karnovsky Plasma Membranes of Mammalian Cells . . 275 J. Richard McIntosh and Edward S. Ogata and Story C. Landis The Axostyle of Saccinobaculus . . . . . 304 J. Richard McIntosh The Axostyle of Saccinobaculus . . . . . 324 G. Benjamin Bouck and David L. Brown Microtubule Biogenesis and Cell Shape in Ochromonas . . . . . . . . . . . . . . . 340 David L. Brown and G. Benjamin Bouck Microtubule Biogenesis and Cell Shape in Ochromonas . . . . . . . . . . . . . . . 360 Michael S. Jensen and Dorothy F. Bainton Temporal Changes in pH Within the Phagocytic Vacuole of the Polymorphonuclear Neutrophilic Leukocyte 379 Juan I. Korenbrot and Dennis T. Brown and Richard A. Cone Membrane Characteristics and Osmotic Behavior of Isolated Rod Outer Segments 389 Fredric S. Fay and P. H. Cooke Reversible Disaggregation of Myofilaments in Vertebrate Smooth Muscle 399 N. Scott McNutt and Lloyd A. Culp and Paul H. Black Contact-Inhibited Revertant Cell Lines Isolated from Sv40-Transformed Cells . . 412 Russell Meints and Eugene Goldwasser The Persistence of Hemopoietic Stem Cells in Vitro . . . . . . . . . . . . . 429 Irving Finger and Patricia Lavanchy and Ann Meany Synthesis of Paramecium Surface Proteins 434 Norman E. Williams and Joseph Frankel Regulation of Microtubules in \bionameTetrahymena . . . . . . . . . . 441 Norman E. Williams and E. Marlo Nelsen Regulation of Microtubules in \bionameTetrahymena . . . . . . . . . . 458 R. Bruce Szamier and Michael V. L. Bennett Rapid Degeneration of Ampullary Electroreceptor Organs After Denervation 466 Asao Hirano and Herbert M. Dembitzer Cerebellar Alterations in the Weaver Mouse . . . . . . . . . . . . . . . . . 478 William J. Grimes and Judith L. Schroeder Dibutyryl Cyclic Adenosine 3' 5' Monophosphate, Sugar Transport, and Regulatory Control of Cell Division in Normal and Transformed Cells . . . . . . 487 Una Smith and J. W. Ryan and D. S. Smith Freeze-Etch Studies of the Plasma Membrane of Pulmonary Endothelial Cells 492 Peter J. Gruber and Wayne M. Becker and Eldon H. Newcomb The Development of Microbodies and Peroxisomal Enzymes in Greening Bean Leaves . . . . . . . . . . . . . . . . . 500 P. Seeman and D. Cheng and G. H. Iles Structure of Membrane Holes in Osmotic and Saponin Hemolysis . . . . . . . . . 519 G. H. Iles and P. Seeman and D. Naylor and B. Cinader Membrane Lesions in Immune Lysis . . . . 528 Susan J. Abrahams and Eric Holtzman Secretion and Endocytosis in Insulin-Stimulated Rat Adrenal Medulla Cells . . . . . . . . . . . . . . . . . 540 Richard D. Allen Structures Linking the Myonemes, Endoplasmic Reticulum, and Surface Membranes in the Contractile Ciliate Vorticella . . . . . . . . . . . . . . . 559 Mary Lake Polan and Susan Friedman and Joseph G. Gall and Walter Gehring Isolation and Characterization of Mitochondrial DNA from \bionameDrosophila Melanogaster . . . . 580 Robert B. Low and Alfred L. Goldberg Nonuniform Rates of Turnover of Myofibrillar Proteins in Rat Diaphragm 590 Paul H. Jewett and Stephen D. Leonard and Joachim R. Sommer Chicken Cardiac Muscle . . . . . . . . . 595 G. Pelletier and R. Puviani Detection of Glycoproteins and Autoradiographic Localization of [$^3$H]Fucose in the Thyroidectomy Cells of Rat Anterior Pituitary Gland . . . . 600 E. Robert Burns and Lawrence E. Scheving Isoproterenol-Induced Phase Shifts in Circadian Rhythm of Mitosis in Murine Corneal Epithelium . . . . . . . . . . . 605 Lawrence K. Schneider RNA Synthesis in Chromosome Connectives 608 J. D. Lutton The Effect of Phagocytosis and Spreading on Macrophage Surface Receptors for Concanavalin A . . . . . . . . . . . . . 611
Richard C. Franson and Moseley Waite Lysosomal Phospholipases A$_1$ and A$_2$ of Normal and \booktitleBacillus Calmette Guerin-Induced Alveolar Macrophages . . . . . . . . . . . . . . 621 Robert W. Rubin and Philip Filner Adenosine 3 ', 5 '-Cyclic Monophosphate in Chlamydomonas Reinhardtii . . . . . . 628 Jane Overton Experimental Manipulation of Desmosome Formation . . . . . . . . . . . . . . . 636 H. Beug and F. E. Katz and G. Gerisch Dynamics of Antigenic Membrane Sites Relating to Cell Aggregation in \bionameDictyostelium Discoideum . . . . 647 Frederick Grinnell and Mary Milam and Paul A. Srere Studies on Cell Adhesion . . . . . . . . 659 J. A. Wright Evidence for Pleiotropic Changes in Lines of Chinese Hamster Ovary Cells Resistant to Concanavalin a and Phytohemagglutinin-P . . . . . . . . . . 666 Michael D. Gershon and Eladio A. Nunez Subcellular Storage Organelles for $5$-Hydroxytryptamine in Parafollicular Cells of the Thyroid Gland . . . . . . . 676 Alex Matter A Morphometric Study on the Nexus of Rat Cardiac Muscle . . . . . . . . . . . . . 690 Martin A. Gorovsky and Stanley Hattman and Gloria Lorick Pleger [$^6$ N]Methyl Adenine in the Nuclear DNA of a Eucaryote, \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 697 D. Bray Branching Patterns of Individual Sympathetic Neurons in Culture . . . . . 702 Mary Bartlett Bunge Fine Structure of Nerve Fibers and Growth Cones of Isolated Sympathetic Neurons in Culture . . . . . . . . . . . 713 Dorothy Gerber and Margaret Davies and Lowell E. Hokin The Effects of Secretagogues on the Incorporation of [2-$^3$H]Myoinositol into Lipid in Cytological Fractions in the Pancreas of the Guinea Pig in Vivo 736 Robert P. Bolender and Ewald R. Weibel A Morphometric Study of the Removal of Phenobarbital-Induced Membranes from Hepatocytes After Cessation of Treatment 746 Robert Nilsson and Elisabeth Peterson and Gustav Dallner Permeability of Microsomal Membranes Isolated from Rat Liver . . . . . . . . 762 H. Rubin and T. Koide Inhibition of DNA Synthesis in Chick Embryo Cultures by Deprivation of Either Serum Or Zinc . . . . . . . . . . . . . 777 P. M. Quinton and C. W. Philpott A Role for Anionic Sites in Epithelial Architecture . . . . . . . . . . . . . . 787 Dorothy R. Pitelka and Susan T. Hamamoto and Joan G. Duafala and Michael K. Nemanic Cell Contacts in the Mouse Mammary Gland 797 Brian Storrie and Giuseppe Attardi Expression of the Mitochondrial Genome in HeLa Cells . . . . . . . . . . . . . 819 Brian Storrie and Giuseppe Attardi Mode of Mitochondrial Formation in HeLa Cells . . . . . . . . . . . . . . . . . 833 Melvyn Weinstock and C. P. Leblond Radioautographic Visualization of the Deposition of a Phosphoprotein at the Mineralization Front in the Dentin of the Rat Incisor . . . . . . . . . . . . 838 E. Knight Interferon: Effect on the Saturation Density to Which Mouse Cells Will Grow in Vitro . . . . . . . . . . . . . . . . 846 James N. Pratley and Nancy K. McQuillen The Role of Microfilaments in Frog Skin Ion Transport . . . . . . . . . . . . . 850 Fred R. Butcher and James F. Perdue Cytochalasin B . . . . . . . . . . . . . 857 Lee-Nien L. Chan and V. M. Ingram Culture of Erythropoietic Cells from Chick Blastoderms . . . . . . . . . . . 861 M. S. Forbes and N. Sperelakis A Labyrinthine Structure Formed from a Transverse Tubule of Mouse Ventricular Myocardium . . . . . . . . . . . . . . . 865 Margaret K. Clark and Paul A. Dahm Phenobarbital-Induced, Membrane-Like Scrolls in the Oenocytes of \bionameMusca Domestica Linnaeus . . . . 870 Walter J. Humphreys and Tomasz J. Wodzicki and Jerome J. Paulin Fractographic Studies of Plastic-Embedded Cells by Scanning Electron Microscopy . . . . . . . . . . 876
Owen Black and Paul D. Webster Protein Synthesis in Pancreas of Fasted Pigeons . . . . . . . . . . . . . . . . 1 N. M. Blackett and D. M. Parry A New Method for Analyzing Electron Microscope Autoradiographs Using Hypothetical Grain Distributions . . . . 9 D. M. Parry and N. M. Blackett Electron Microscope Autoradiography of Erythroid Cells Using Radioactive Iron 16 Michael Edidin and Douglas Fambrough Fluidity of the Surface of Cultured Muscle Fibers . . . . . . . . . . . . . 27 Alexander L. Kisch and Robert O. Kelley and Harry Crissman and Linda Paxton Dimethyl Sulfoxide-Induced Reversion of Several Features of Polyoma Transformed Baby Hamster Kidney Cells (Bhk-21) . . . 38 Camillo Peracchia Low Resistance Junctions in Crayfish . . 54 Camillo Peracchia Low Resistance Junctions in Crayfish . . 66 M. M. Magalhães and Antonio Coimbra Electron Microscope Autoradiographic Detection of Sites of Protein Synthesis in the Rabbit Retina Müler Cells . . . . 77 Saul Teichberg and Eric Holtzman Axonal Agranular Reticulum and Synaptic Vesicles in Cultured Embryonic Chick Sympathetic Neurons . . . . . . . . . . 88 J. V. Anastasia and R. L. McCarl Effects of Cortisol on Cultured Rat Heart Cells . . . . . . . . . . . . . . 109 Susan Y. Schmidt and Richard N. Lolley Cyclic-Nucleotide Phosphodiesterase . . 117 C. Brailovsky and M. Trudel and R. Lallier and V. N. Nigam Growth of Normal and Transformed Rat Embryo Fibroblasts . . . . . . . . . . . 124 R. E. Stephens A Thermodynamic Analysis of Mitotic Spindle Equilibrium at Active Metaphase 133 J. G. Williams and I. A. MacPherson The Differential Effect of Actinomycin D in Normal and Virus-Transformed Cells 148 J. J. Geuze and C. Poort Cell Membrane Resorption in the Rat Exocrine Pancreas Cell After in Vivo Stimulation of the Secretion, As Studied by in Vitro Incubation with Extracellular Space Markers . . . . . . 159 Richard W. Young The Role of the Golgi Complex in Sulfate Metabolism . . . . . . . . . . . . . . . 175 Elizabeth D. Hay and James W. Dodson Secretion of Collagen by Corneal Epithelium . . . . . . . . . . . . . . . 190 Bunsuke Osogoe and R. W. Tyler and N. B. Everett The Patterns of Labeling of Germinal-Center Cells with Tritiated Deoxycytidine . . . . . . . . . . . . . 215 Kenji Tanaka Intranuclear Microtubule Organizing Center in Early Prophase Nuclei of the Plasmodium of the Slime Mold, \bionamePhysarum Polycephalum . . . . . 220 Kenneth G. Orloff and Richard L. McCarl The Effects of Metabolic Inhibitors on Cultured Rat Heart Cells . . . . . . . . 225 Gary W. Grimes Morphological Discontinuity of Kinetosomes During the Life Cycle of Oxytricha Fallax . . . . . . . . . . . . 229 Ephraim Yavin and John H. Menkes The Culture of Dissociated Cells from Rat Cerebral Cortex . . . . . . . . . . 232 John L. Skosey and Donald Chow and Evelyn Damgaard and Leif B. Sorensen Effect of Cytochalasin B on Response of Human Polymorphonuclear Leukocytes to Zymosan . . . . . . . . . . . . . . . . 237 Arne Andersson and Birger Petersson and Jan Westman and John Edwards and Gudmar Lundqvist and Claes Hellerström Tissue Culture of A$_2$ Cell-Rich Pancreatic Islets Isolated from Guinea Pigs . . . . . . . . . . . . . . . . . . 241 Istvan Hüttner and Michel Boutet and Robert H. More Gap Junctions in Arterial Endothelium 247 David Lagunoff Membrane Fusion During Mast Cell Secretion . . . . . . . . . . . . . . . 252
R. W. D. Rowe The Ultrastructure of Z Disks from White, Intermediate, and Red Fibers of Mammalian Striated Muscles . . . . . . . 261 T. Ootaki and J. J. Wolken Octahedral Crystals in Phycomyces. II 278 Martha E. Fedorko and Nicholas L. Cross and James G. Hirsch Appearance and Distribution of Ferritin in Mouse Peritoneal Macrophages in Vitro After Uptake of Heterologous Erythrocytes . . . . . . . . . . . . . . 289 Jacquelyn C. Pendland and H. C. Aldrich Ultrastructural Organization of Chloroplast Thylakoids of the Green Alga ``Oocystis Marssonii'' . . . . . . . . . 306 J. E. Heuser and T. S. Reese Evidence for Recycling of Synaptic Vesicle Membrane During Transmitter Release at the Frog Neuromuscular Junction . . . . . . . . . . . . . . . . 315 Virginia H. Black and Bruce I. Bogart Peroxisomes in Inner Adrenocortical Cells of Fetal and Adult Guinea Pigs . . 345 J. B. Rattner and Stephanie G. Phillips Independence of Centriole Formation and DNA Synthesis . . . . . . . . . . . . . 359 Garth L. Nicolson Anionic Sites of Human Erythrocyte Membranes . . . . . . . . . . . . . . . 373 M. A. Wainberg and C. Howe and G. C. Godman Enhancement of Sendai Virus-Mediated Cell Fusion by Cupric Ions . . . . . . . 388 D. B. Thomas and Gay Medley and C. A. Lingwood Growth Inhibition of Murine Tumor Cells, in Vitro, by Puromycin, [$^6$N]O$^{2'}$-Dibutyryl 3',5'-Adenosine Monophosphate, or Adenosine . . . . . . . . . . . . . . . 397 Jean R. Wrathall and Constance Oliver and Selma Silagi and Edward Essner Suppression of Pigmentation in Mouse Melanoma Cells by 5-Bromodeoxyuridine 406 Nicolae Simionescu and Maia Simionescu and George E. Palade Permeability of Muscle Capillaries to Exogenous Myoglobin . . . . . . . . . . 424 Miklós Müller Biochemical Cytology of Trichomonad Flagellates . . . . . . . . . . . . . . 453 Annemarie Herzfeld and Micheline Federman and Olga Greengard Subcellular Morphometric and Biochemical Analyses of Developing Rat Hepatocytes 475 Rolf Seljelid and Samuel C. Silverstein and Zanvil A. Cohn The Effect of Poly-L-Lysine on the Uptake of Reovirus Double-Stranded RNA in Macrophages in Vitro . . . . . . . . 484 B. Ceccarelli and W. P. Hurlbut and A. Mauro Turnover of Transmitter and Synaptic Vesicles at the Frog Neuromuscular Junction . . . . . . . . . . . . . . . . 499 A. R. Stevens and P. F. Pachler RNA Synthesis and Turnover During Density-Inhibited Growth and Encystment of \bionameAcanthamoeba Castellanii . . 525 R. Sederoff and R. Clynes and M. Poncz and S. Hachtel RNA Synthesis by Exogenous RNA Polymerase on Cytological Preparations of Chromosomes . . . . . . . . . . . . . 538 K. T. Tokuyasu A Technique for Ultracryotomy of Cell Suspensions and Tissues . . . . . . . . 551 H. W. Seyberth and H. Schmidt-Gayk and K. H. Jakobs and E. Hackenthal Cyclic Adenosine Monophosphate in Phagocytizing Granulocytes and Alveolar Macrophages . . . . . . . . . . . . . . 567 N. Kislev and C. M. Spolsky and J. M. Eisenstadt Effect of Chloramphenicol on the Ultrastructure of Mitochondria in Sensitive and Resistant Strains of HeLa 571 John N. Telford and Efraim Racker A Method for Increasing Contrast of Mitochondrial Inner Membrane Spheres in Thin Sections of Epon-Araldite Embedded Tissue . . . . . . . . . . . . . . . . . 580 E. Weidner and W. Trager Adenosine Triphosphate in the Extracellular Survival of an Intracellular Parasite (\bionameNosema Michaelis, Microsporidia) . . . . . . . 586 Rhea J. C. Levine and Maynard M. Dewey and David E. Colflesh Unusual Striated Thick Filaments in Limulus Skeletal Muscle . . . . . . . . 591 Janet M. Ledingham and F. O. Simpson Bundles of Intracellular Tubules in Renal Medullary Interstitial Cells . . . 594
Robert W. Rubin and William P. Cunningham Partial Purification and Phosphotungstate Solubilization of Basal Bodies and Kinetodesmal Fibers from \bionameTetrahymena Pyriformis . . . . . 601 Francine Benes and Joan A. Higgins and Russell J. Barrnett Ultrastructural Localization of Phospholipid Synthesis in the Rat Trigeminal Nerve During Myelination . . 613 Thomas L. Rothstein and J. J. Blum Lysosomal Physiology in \bionameTetrahymena . . . . . . . . . . 630 Roger B. Howard and Joseph C. Lee and Leroy A. Pesch The Fine Structure, Potassium Content, and Respiratory Activity of Isolated Rat Liver Parenchymal Cells Prepared by Improved Enzymatic Techniques . . . . . 642 J. M. Lord and T. Kagawa and T. S. Moore and H. Beevers Endoplasmic Reticulum As the Site of Lecithin Formation in Castor Bean Endosperm . . . . . . . . . . . . . . . 659 Pamela Leban Johnston and Edgar F. Carell Vitamin B$_{12}$ and the Macromolecular Composition of Euglena . . . . . . . . . 668 Leslie A. Dendy and Russell L. Deter and Charles W. Philpott Localization of Na$^+$, K$^+$-ATPase and other enzymes in teleost pseudobranch 675 Leslie A. Dendy and Charles W. Philpott and Russell L. Deter Localization of Na$^+$, K$^+$-ATPase and other enzymes in teleost pseudobranch 689 B. Huang and D. R. Pitelka The Contractile Process in the Ciliate, \bionameStentor Coeruleus . . . . . . . 704 Harvey Bank and Peter Mazur Visualization of Freezing Damage . . . . 729 Charles K. Jablecki and John E. Heuser and Seymour Kaufman Autoradiographic Localization of New RNA Synthesis in Hypertrophying Skeletal Muscle . . . . . . . . . . . . . . . . . 743 Stephen H. Howell and Jay A. Naliboff Conditional Mutants in Chlamydomonas Reinhardtii Blocked in the Vegetative Cell Cycle . . . . . . . . . . . . . . . 760 Martin A. Gorovsky and Gloria Lorick Pleger and Josephine Bowen Keevert and Carol A. Johmann Studies on Histone Fraction F2A1 in Macro- and Micronuclei of \bionameTetrahymena Pyriformis . . . . . 773 Story C. Landis Ultrastructural Changes in the Mitochondria of Cerebellar Purkinje Cells of Nervous Mutant Mice . . . . . . 782 Nam-Hai Chua and G. Blobel and P. Siekevitz Isolation of Cytoplasmic and Chloroplast Ribosomes and Their Dissociation into Active Subunits from Chlamydomonas Reinhardtii . . . . . . . . . . . . . . 798 Keith Porter and David Prescott and Jearl Frye Changes in Surface Morphology of Chinese Hamster Ovary Cells During the Cell Cycle . . . . . . . . . . . . . . . . . 815 R. W. Rubin and L. P. Everhart The Effect of Cell-To-Cell Contact on the Surface Morphology of Chinese Hamster Ovary Cells . . . . . . . . . . 837 Bruce Magun Two Actions of Cyclic AMP on Melanosome Movement in Frog Skin . . . . . . . . . 845 Wiktor Djaczenko and Carmen Calenda Visualization of Polysaccharides in the Cuticle of Oligochaeta by the Tris $1$-Aziridinyl Phosphine Oxide Method 859 Cheng-Ming Chang and Robert D. Goldman The Localization of Actin-Like Fibers in Cultured Neuroblastoma Cells As Revealed by Heavy Meromyosin Binding . . . . . . 867 Velma C. Chambers The Use of Ruthenium Red in an Electron Microscope Study of Cytophagocytosis . . 872 John W. Fuseler Repetitive Procurement of Mature Gametes from Individual Sea Stars and Sea Urchins . . . . . . . . . . . . . . . . 879
A. Martinez-Palomo and D. Benitez and J. Alanis Selective Deposition of Lanthanum in Mammalian Cardiac Cell Membranes . . . . 1 Wolfgang Klietmann and Nobuhiro Sato and Margit M. K. Nass Establishment and Characterization of Ethidium Bromide Resistance in Simian Virus $ 40$-Transformed Hamster Cells 11 Robert B. Zurier and Sylvia Hoffstein and Gerald Weissmann Mechanisms of Lysosomal Enzyme Release from Human Leukocytes . . . . . . . . . 27 Frank A. Rawlins A Time-Sequence Autoradiographic Study of the in Vivo Incorporation of [1, 2-$^3$H]Cholesterol into Peripheral Nerve Myelin . . . . . . . . . . . . . . 42 David M. Phillips and Stephanie Gordon Phillips Repopulation of Postmitotic Nucleoli by Preformed RNA . . . . . . . . . . . . . 54 R. A. Corradino Embryonic Chick Intestine in Organ Culture . . . . . . . . . . . . . . . . 64 Peter S. Spencer and Edith R. Peterson and Ricardo Madrid A. and Cedric S. Raine Effects of Thallium Salts on Neuronal Mitochondria in Organotypic Cord-Ganglia-Muscle Combination Cultures 79 B. R. Brinkley and Potu N. Rao Nitrous Oxide: Effects on the Mitotic Apparatus and Chromosome Movement in HeLa Cells . . . . . . . . . . . . . . . 96 Mark Nameroff and John A. Trotter and John M. Keller and Erlynda Munar Inhibition of Cellular Differentiation by Phospholipase C . . . . . . . . . . . 107 Carol Johmann and Ronald A. Eckhardt and Martin A. Gorovsky The Histones Associated with Condensed and Extended Chromatin of Mouse Liver 119 John F. Aronson Nuclear Membrane Fusion in Fertilized Lytechinus Variegatus Eggs . . . . . . . 126 Ken Kadota and Tomoko Kadota Isolation of Coated Vesicles, Plain Synaptic Vesicles, and Flocculent Material from a Crude Synaptosome Fraction of Guinea Pig Whole Brain . . . 135 Joan Gil and Oscar K. Reiss Isolation and Characterization of Lamellar Bodies and Tubular Myelin from Rat Lung Homogenates . . . . . . . . . . 152 Richard I. Woodruff and William H. Telfer Polarized Intercellular Bridges in Ovarian Follicles of the Cecropia Moth 172 Richard Rodewald Intestinal Transport of Antibodies in the Newborn Rat . . . . . . . . . . . . 189 Portia A. Holt and John O. Corliss Pattern Variability in Microtubular Arrays Associated with the Tentacles of Actinobolina (Ciliatea: Gymnostomatida) 213 B. Allen Flaxman and Francis V. Cavoto Low-Resistance Junctions in Epithelial Outgrowths from Normal and Cancerous Epidermis in Vitro . . . . . . . . . . . 219 Francis V. Cavoto and B. Allen Flaxman Low-Resistance Pathways Between Mitotic and Interphase Epidermal Cells in Vitro 223 J. F. David-Ferreira and K. L. David-Ferreira Gap Junction-Ribosome Association After Autolysis . . . . . . . . . . . . . . . 226 Lucy T. Comly Microfilaments in Chaos Carolinensis . . 230 W. F. Harris The Geometry of Triplets in Ciliary Basal Bodies from Primate Oviducts . . . 237 Alexander Sutherland and Gregory A. Antipa and Charles F. Ehret Ultracytochemical Observations of Glycogen Synthesis and Storage During Infradian Growth of \bionameTetrahymena Pyriformis . . . . . . . . . . . . . . . 240 Robert H. Gray and Joan B. Peterson and Hans Ris The Organization of Yeast Nucleohistone Fibers . . . . . . . . . . . . . . . . . 244
Dorothy Ford Bainton Sequential Degranulation of the Two Types of Polymorphonuclear Leukocyte Granules During Phagocytosis of Microorganisms . . . . . . . . . . . . . 249 J. F. Perdue The Distribution, Ultrastructure, and Chemistry of Microfilaments in Cultured Chick Embryo Fibroblasts . . . . . . . . 265 M. John Chapman and Leonard R. Miller and Joseph A. Ontko Localization of the Enzymes of Ketogenesis in Rat Liver Mitochondria 284 Vijai N. Nigam and R. Lallier and C. Brailovsky Ganglioside Patterns and Phenotypic Characteristics in a Normal Variant and a Transformed Back Variant of a Simian Virus $ 40$-Induced Hamster Tumor Cell Line . . . . . . . . . . . . . . . . . . 307 Robert S. Lake Further Characterization of the F1-Histone Phosphokinase of Metaphase-Arrested Animal Cells . . . . 317 Miriam D. Rosenthal and Joseph B. Warshaw Interaction of Fatty Acid and Glucose Oxidation by Cultured Heart Cells . . . 332 Kenneth D. Ley and Marilyn M. Murphy Synchronization of Mitochondrial DNA Synthesis in Chinese Hamster Cells (Line Cho) Deprived of Isoleucine . . . . . . 340 Thomas P. Stossel Quantitative Studies of Phagocytosis . . 346 Lajos Pikó and David G. Chase Role of the Mitochondrial Genome During Early Development in Mice . . . . . . . 357 A. H. C. Huang and H. Beevers Localization of Enzymes Within Microbodies . . . . . . . . . . . . . . 379 Philippa Claude and Daniel A. Goodenough Fracture Faces of Zonulae Occludentes from ``Tight'' and ``Leaky'' Epithelia 390 B. L. A. Carter and H. O. Halvorson Periodic Changes in Rate of Amino Acid Uptake During Yeast Cell Cycle . . . . . 401 Roger Hand and Igor Tamm DNA Replication: Direction and Rate of Chain Growth in Mammalian Cells . . . . 410 Allen Bennett and Lawrence Bogorad Complementary Chromatic Adaptation in a Filamentous Blue-Green Alga . . . . . . 419 Gert Kreibich and Pascale Debey and David D. Sabatini Selective Release of Content from Microsomal Vesicles Without Membrane Disassembly . . . . . . . . . . . . . . 436 Mathew P. Daniels Fine Structural Changes in Neurons and Nerve Fibers Associated with Colchicine Inhibition of Nerve Fiber Formation in Vitro . . . . . . . . . . . . . . . . . 463 A. G. de Bianchi and W. R. Terra and F. J. S. Lara Formation of Salivary Secretion in \bionameRhynchosciara Americana . . . . 470 Bert M. Zuckerman and Marian Kisiel and Stanley Himmelhoch Unusual Mitochondrial Cristae in the Vinegar Eelworm . . . . . . . . . . . . 476 Ezzatollah Keyhani Ribosomal Granules Associated with Outer Mitochondrial Membrane in Aerobic Yeast Cells . . . . . . . . . . . . . . . . . 480 William H. Massover Complex Surface Invaginations in Frog Oocytes . . . . . . . . . . . . . . . . 485 Kenneth D. Noonan and Arnold J. Levine and Max M. Burger Cell Cycle-Dependent Changes in the Surface Membrane As Detected with [$^3$H] Concanavalin A . . . . . . . . . 491 Daniel K. Podolsky and Milton M. Weiser Specific Selection of Mitotically Active Intestinal Cells by Concanavalin A-Derivatized Fibers . . . . . . . . . . 497
C. Tougard and B. Kerdelhue and A. Tixier-Vidal and M. Jutisz Light and Electron Microscope Localization of Binding Sites of Antibodies Against Ovine Luteinizing Hormone and Its Two Subunits in Rat Adenohypophysis Using Peroxidase-Labeled Antibody Technique . . . . . . . . . . . 503 S. Githens and M. L. Karnovsky Biochemical Changes During Growth and Encystment of the Cellular Slime Mold Polysphondylium Pallidum . . . . . . . . 522 S. Githens and M. L. Karnovsky Phagocytosis by the Cellular Slime Mold Polysphondylium Pallidum During Growth and Development . . . . . . . . . . . . 536 Monica J. Trigg and Salome Gluecksohn-Waelsch Ultrastructural Basis of Biochemical Effects in a Series of Lethal Alleles in the Mouse . . . . . . . . . . . . . . . 549 Robert R. Klevecz and Leon N. Kapp Intermittent DNA Synthesis and Periodic Expression of Enzyme Activity in the Cell Cycle of Wi-38 . . . . . . . . . . 564 Maynard M. Dewey and Rhea J. C. Levine and David E. Colflesh Structure of Limulus Striated Muscle . . 574 Richard O. Williams and Lawrence A. Loeb Zinc Requirement for DNA Replication in Stimulated Human Lymphocytes . . . . . . 594 Frederick Grinnell Concanavalin a Increases the Strength of Baby Hamster Kidney Cell Attachment to Substratum . . . . . . . . . . . . . . . 602 Yoshitaka Obara and Hiroshi Yoshida and Lee S. Chai and Herbert Weinfeld and Avery A. Sandberg Contrast between the environmental pH dependencies of prophasing and nuclear membrane formation in interphase--metaphase cells . . . . . . 608 Keith E. Summers and I. R. Gibbons Effects of Trypsin Digestion on Flagellar Structures and Their Relationship to Motility . . . . . . . . 618 Clara Franzini-Armstrong The Structure of a Simple Z Line . . . . 630 H. Schmitt and H. Grossfeld and U. Z. Littauer Mitochondrial Biogenesis During Differentiation of Artemia Salina Cysts 643 Matthew M. LaVail Kinetics of Rod Outer Segment Renewal in the Developing Mouse Retina . . . . . . 650 C. F. Millette and P. G. Spear and W. E. Gall and G. M. Edelman Chemical Dissection of Mammalian Spermatozoa . . . . . . . . . . . . . . 662 William E. Grove and Terry C. Johnson and Paul Kelly and Marvin Luttges Qualitative and Quantitative Morphological Changes in Subcellular Fractions from Mouse Cerebral Cortex During Postnatal Development . . . . . . 676 E. Joan Blanchette-Mackie and Robert O. Scow Effects of Lipoprotein Lipase on the Structure of Chylomicrons . . . . . . . 689 Leslie Wilson and Isaura Meza The Mechanism of Action of Colchicine 709 Paula F. Dehn and Robin A. Wallace Sequestered and Injected Vitellogenin 721 P. M. Quinton and Ernest M. Wright and John McD. Tormey Localization of Sodium Pumps in the Choroid Plexus Epithelium . . . . . . . 724
William R. Jeffery and Joseph Frankel and Lawrence E. de Bault and Leslie M. Jenkins Analysis of the Schedule of DNA Replication in Heat-Synchronized \bionameTetrahymena . . . . . . . . . . 1 Eve P. Reaven and Stanton G. Axline Subplasmalemmal Microfilaments and Microtubules in Resting and Phagocytizing Cultivated Macrophages . . 12 Yukio Ikehara and Henry C. Pitot Localization of Polysome-Bound Albumin and Serine Dehydratase in Rat Liver Cell Fractions . . . . . . . . . . . . . . . 28 J. H. Ehrenreich and J. J. M. Bergeron and P. Siekevitz and G. E. Palade Golgi Fractions Prepared from Rat Liver Homogenates . . . . . . . . . . . . . . 45 J. J. M. Bergeron and J. H. Ehrenreich and P. Siekevitz and G. E. Palade Golgi Fractions Prepared from Rat Liver Homogenates . . . . . . . . . . . . . . 73 John G. Bluemink and Siegfried W. de Laat New Membrane Formation During Cytokinesis in Normal and Cytochalasin B-Treated Eggs of \bionameXenopus Laevis 89 Lewis G. Tilney and Sadashi Hatano and Harunori Ishikawa and Mark S. Mooseker The Polymerization of Actin: Its Role in the Generation of the Acrosomal Process of Certain Echinoderm Sperm . . . . . . 109 Lidia S. Watrud and Albert H. Ellingboe Cobalt As a Mitochondrial Density Marker in a Study of Cytoplasmic Exchange During Mating of Schizophyllum Commune 127 Kenneth D. Noonan and Max M. Burger The Relationship of Concanavalin a Binding to Lectin-Initiated Cell Agglutination . . . . . . . . . . . . . 134 Jack Rosenbluth Membrane Specialization at an Insect Myoneural Junction . . . . . . . . . . . 143 T. Simmons and P. Heywood and L. Hodge Nuclear Envelope-Associated Resumption of RNA Synthesis in Late Mitosis of HeLa Cells . . . . . . . . . . . . . . . . . 150 Michel Rabinovitch and Mary Jo de Stefano Manganese Stimulates Adhesion and Spreading of Mouse Sarcoma I Ascites Cells . . . . . . . . . . . . . . . . . 165 William E. Bowers Lysosomes in Rat Thoracic Duct Lymphocytes Fractionated by Zonal Centrifugation . . . . . . . . . . . . . 177 E. Bonucci and M. Derenzini and V. Marinozzi The Organic-Inorganic Relationship in Calcified Mitochondria . . . . . . . . . 185 Samuel James Davidson Protein Absorption by Renal Cells . . . 213 Adriana Hodârnâu and Silvia Dancea and Octavian Bârzu Isolation of Highly Purified Mitochondria from Rat Pancreas . . . . . 222 Gary W. Conrad and Daniel C. Williams and F. Rudolf Turner and Kenneth M. Newrock and Rudolf A. Raff Microfilaments in the Polar Lobe Constriction of Fertilized Eggs of Ilyanassa Obsoleta . . . . . . . . . . . 228 R. G. Sherman Unique Arrangement of Glial Membranes Between Adjacent Neuromuscular Synapses in a Spider Muscle . . . . . . . . . . . 234 Martin L. Pall Sexual Induction in Volvox Carteri . . . 238 Bruce Paterson and Joav Prives Appearance of Acetylcholine Receptor in Differentiating Cultures of Embryonic Chick Breast Muscle . . . . . . . . . . 241 Gloria D. Massaro and Donald Massaro Pulmonary Granular Pneumocytes . . . . . 246 Herbert L. Cooper Degradation of 28S RNA Late in Ribosomal RNA Maturation in Nongrowing Lymphocytes and Its Reversal After Growth Stimulation . . . . . . . . . . . . . . 250 R. A. Waugh and T. L. Spray and J. R. Sommer Fenestrations of Sarcoplasmic Reticulum 254 Manley McGill and T. C. Hsu and B. R. Brinkley Electron-Dense Structures in Mitochondria Induced by Short-Term Ethidium Bromide Treatment . . . . . . . 260
Lewis G. Tilney and Joseph Bryan and Doris J. Bush and Keigi Fujiwara and Mark S. Mooseker and Douglas B. Murphy and Daniel H. Snyder Microtubules: Evidence for 13 Protofilaments . . . . . . . . . . . . . 267 Colin R. Hopkins and Marilyn G. Farquhar Hormone Secretion by Cells Dissociated from Rat Anterior Pituitaries . . . . . 276 Donald E. Olins and Everline B. Wright Glutaraldehyde Fixation of Isolated Eucaryotic Nuclei . . . . . . . . . . . 304 Sarah P. Gibbs and Ronald J. Poole Autoradiographic Evidence for Many Segregating DNA Molecules in the Chloroplast of Ochromonas Danica . . . . 318 Richard E. Mains and Paul H. Patterson Primary Cultures of Dissociated Sympathetic Neurons . . . . . . . . . . 329 Richard E. Mains and Paul H. Patterson Primary Cultures of Dissociated Sympathetic Neurons . . . . . . . . . . 346 Richard E. Mains and Paul H. Patterson Primary Cultures of Dissociated Sympathetic Neurons . . . . . . . . . . 361 Robert L. Stavis and Rona Hirschberg Phototaxis in Chlamydomonas Reinhardtii 367 D. L. Taylor and J. S. Condeelis and P. L. Moore and R. D. Allen The Contractile Basis of Amoeboid Movement . . . . . . . . . . . . . . . . 378 Garth L. Nicolson and Richard G. Painter Anionic Sites of Human Erythrocyte Membranes . . . . . . . . . . . . . . . 395 Neil I. Spielholz and William G. Van der Kloot Localization and Properties of the Cholinesterase in Crustacean Muscle . . 407 F. C. Charalampous and N. K. Gonatas and A. D. Melbourne Isolation and Properties of the Plasma Membrane of Kb Cells . . . . . . . . . . 421 Nicholas K. Gonatas and Stratis Avrameas Detection of Plasma Membrane Carbohydrates with Lectin Peroxidase Conjugates . . . . . . . . . . . . . . . 436 Judith E. Armstrong and Russell L. Jones Osmotic regulation of $ \alpha $-amylase synthesis and polyribosome formation in aleurone cells of barley . . . . . . . . 444 W. W. Schlaepfer and R. P. Bunge Effects of Calcium Ion Concentration on the Degeneration of Amputated Axons in Tissue Culture . . . . . . . . . . . . . 456 Brian Storrie Antagonism by Dibutyryl Adenosine Cyclic 3',5'-Monophosphate and Testosterone of Cell Rounding Reactions . . . . . . . . 471 Joyce P. Cox and Manfred L. Karnovsky The Depression of Phagocytosis by Exogenous Cyclic Nucleotides, Prostaglandins, and Theophylline . . . . 480 Paul B. Lazarow and Christian de Duve The Synthesis and Turnover of Rat Liver Peroxisomes . . . . . . . . . . . . . . 491 Paul B. Lazarow and Christian de Duve The Synthesis and Turnover of Rat Liver Peroxisomes . . . . . . . . . . . . . . 507 P. P. C. Graziadei and R. S. DeHan Neuronal Regeneration in Frog Olfactory System . . . . . . . . . . . . . . . . . 525 Linda D. Heding and David A. Wolff The Cytochemical Examination of Poliovirus-Induced Cell Damage . . . . . 530 Earl L. Parr and Jane S. Oei Immobilization of Membrane H-2 Antigens by Paraformaldehyde Fixation . . . . . . 537 Issei Mabuchi A Myosin-Like Protein in the Cortical Layer of the Sea Urchin Egg . . . . . . 542
C. W. Abell and T. M. Monahan The Role of Adenosine 3',5'-Cyclic Monophosphate in the Regulation of Mammalian Cell Division . . . . . . . . 549 William B. Neaves Permeability of Sertoli Cell Tight Junctions to Lanthanum After Ligation of Ductus Deferens and Ductuli Efferentes 559 C. Richard Zobel Effect of Solution Composition and Proteolysis on the Conformation of Axonemal Components . . . . . . . . . . 573 R. Bruce Nicklas Methods for Gentle, Differential Heating of Part of a Single Living Cell . . . . 595 H. Bruce Bosmann Molecules at the External Nuclear Surface . . . . . . . . . . . . . . . . 601 P. R. Gabe and L. E. de Bault Macromolecular Syntheses Related to the Reproductive Cyst of \bionameTetrahymena Patula . . . . . . . . . . . . . . . . . 615 Leo Miller Control of 5S RNA Synthesis During Early Development of Anucleolate and Partial Nucleolate Mutants of \bionameXenopus Laevis . . . . . . . . . . . . . . . . . 624 Keith R. Porter and George J. Todaro and Virginia Fonte A Scanning Electron Microscope Study of Surface Features of Viral and Spontaneous Transformants of Mouse Balb\slash 3T3 Cells . . . . . . . . . . 633 Samuel Dales and Konrad C. Hsu and Ariaki Nagayama The Fine Structure and Immunological Labeling of the Achromatic Mitotic Apparatus After Disruption of Cell Membranes . . . . . . . . . . . . . . . 643 J. Derksen and H. D. Berendes and E. Willart Production and Release of a Locus-Specific Ribonucleoprotein Product in Polytene Nuclei of \bionameDrosophila Hydei . . . . . . . . . . . . . . . . . 661 Helmut M. Maul and Betty Yee Li Hsu and Thaddeus M. Borun and Gerd G. Maul Effect of Metabolic Inhibitors on Nuclear Pore Formation During the HeLa S$_3$ Cell Cycle . . . . . . . . . . . . 669 Pierluigi Gambetti and Lucila Autilio-Gambetti and Brenda Shafer and LaDorna Pfaff Quantitative Autoradiographic Study of Labeled RNA in Rabbit Optic Nerve After Intraocular Injection of [$^3$H]Uridine 677 John T. Knowler and Harold L. Moses and Thomas C. Spelsberg Comparison and Characterization of Nuclear Isolation Procedures As Applied to Chick Oviduct . . . . . . . . . . . . 685 Ursula Bretz and Marco Baggiolini Association of the Alkaline Phosphatase of Rabbit Polymorphonuclear Leukocytes with the Membrane of the Specific Granules . . . . . . . . . . . . . . . . 696 John H. Lillie and Seong S. Han Secretory Protein Synthesis in the Stimulated Rat Parotid Gland . . . . . . 708 D. Montgomery Bissell and Lydia E. Hammaker and Urs A. Meyer Parenchymal Cells from Adult Rat Liver in Nonproliferating Monolayer Culture 722 Geoffrey S. Chapman and Albert L. Jones and Urs A. Meyer and D. Montgomery Bissell Parenchymal Cells from Adult Rat Liver in Nonproliferating Monolayer Culture 735 A. Konishi and W. S. Beacham and C. C. Hunt Centrioles in Intrafusal Muscle Fibers 749 Beth Burnside and Chris Kozak and F. C. Kafatos Tubulin Determination by an Isotope Dilution-Vinblastine Precipitation Method . . . . . . . . . . . . . . . . . 755 Alois Knüsel and Béatrice Lehner and Clive C. Kuenzle and Gonzague S. Kistler Isolation of Neuronal Nuclei from Rat Brain Cortex . . . . . . . . . . . . . . 762 Harry A. Crissman and John A. Steinkamp Rapid, Simultaneous Measurement of DNA, Protein, and Cell Volume in Single Cells from Large Mammalian Cell Populations 766 J. J. M. Bergeron and W. H. Evans and I. I. Geschwind Insulin Binding to Rat Liver Golgi Fractions . . . . . . . . . . . . . . . 771 Yoshiaki Kuriyama and David J. L. Luck Membrane-Associated Ribosomes in Mitochondria of Neurospora Crassa . . . 776 Blair Bowers and Edward D. Korn Cytochemical Identification of Phosphatase Activity in the Contractile Vacuole of \bionameAcanthamoeba Castellanii . . . . . . . . . . . . . . 784
Tsuyoshi Sawai and Mitsuki Yoneda Wave of Stiffness Propagating Along the Surface of the Newt Egg During Cleavage 1 Marilyn G. Farquhar and J. J. M. Bergeron and George E. Palade Cytochemistry of Golgi Fractions Prepared from Rat Liver . . . . . . . . 8 Howard J. Allen and Charles Ault and Richard J. Winzler and James F. Danielli Chemical Characterization of the Isolated Cell Surface of Amoeba . . . . 26 A. L. Kierszenbaum and Laura L. Tres Nucleolar and Perichromosomal RNA Synthesis During Meiotic Prophase in the Mouse Testis . . . . . . . . . . . . . . 39 Joel B. Baseman and Domenic Paolini and Harold Amos Stimulation by Insulin of RNA Synthesis in Chick Fibroblasts . . . . . . . . . . 54 Maurice M. Margulies and Allan Michaels Ribosomes Bound to Chloroplast Membranes in Chlamydomonas Reinhardtii . . . . . . 65 William C. Dewel and Wallis H. Clark A Fine Structural Investigation of Surface Specializations and the Cortical Reaction in Eggs of the Cnidarian Bunodosoma Cavernata . . . . . . . . . . 78 Melvyn Weinstock and C. P. Leblond Synthesis, Migration, and Release of Precursor Collagen by Odontoblasts As Visualized by Radioautography After [$^3$H]Proline Administration . . . . . 92 Maia Simionescu and Nicolae Simionescu and George E. Palade Morphometric Data on the Endothelium of Blood Capillaries . . . . . . . . . . . 128 Harold P. Erickson Microtubule Surface Lattice and Subunit Structure and Observations on Reassembly 153 James B. Wade and Morris J. Karnovsky The Structure of the Zonula Occludens 168 Han van Rijn and Marinus M. Bevers and Roeland van Wijk and Wesley D. Wicks Regulation of Phosphoenolpyruvate Carboxykinase and Tyrosine Transaminase in Hepatoma Cell Cultures . . . . . . . 181 John A. McIntyre and Norton B. Gilula and Morris J. Karnovsky Cryoprotectant-Induced Redistribution of Intramembranous Particles in Mouse Lymphocytes . . . . . . . . . . . . . . 192 I. Brent Heath Mitosis in the Fungus Thraustotheca Clavata . . . . . . . . . . . . . . . . 204 Jamison Gilder and James Cronshaw A Biochemical and Cytochemical Study of Adenosine Triphosphatase Activity in the Phloem of Nicotian a Tabacum . . . . . . 221 Garth L. Nicolson and S. J. Singer The Distribution and Asymmetry of Mammalian Cell Surface Saccharides Utilizing Ferritin-Conjugated Plant Agglutinins As Specific Saccharide Stains . . . . . . . . . . . . . . . . . 236 Jeffrey E. Froehlich and Martin Rachmeler Inhibition of Cell Growth in the G$_1$ Phase by Adenosine 3',5'-Cyclic Monophosphate . . . . . . . . . . . . . 249 Gary Bennett and C. P. Leblond and Antonio Haddad Migration of Glycoprotein from the Golgi Apparatus to the Surface of Various Cell Types As Shown by Radioautography After Labeled Fucose Injection into Rats . . . 258 Richard D. Sjolund and Donna D. Smith Freeze-Fracture Studies of Photosynthetically Deficient ``Supergranal'' Chloroplasts in Tissue Cultures Containing Virus-Like Particles 285 G. H. Cope and M. A. Williams Improved Preservation of Parotid Tissue for Electron Microscopy . . . . . . . . 292 Joachim Stadleb and Werner W. Franke Characterization of the Colchicine Binding of Membrane Fractions from Rat and Mouse Liver . . . . . . . . . . . . 297 Volloer Herzog and H. Dariush Fahimi The Effect of Glutaraldehyde on Catalase 303 J. T. Stasny and R. C. Burns and B. D. Korant and R. W. F. Hardy Electron Microscopy of the Mo-Fe Protein from Azotobacter Nitrogenase . . . . . . 311 Dennis M. D. Landis and T. S. Reese Arrays of Particles in Freeze-Fractured Astrocytic Membranes . . . . . . . . . . 316 Keith Summers ATP-Induced Sliding of Microtubules in Bull Sperm Flagella . . . . . . . . . . 321
Marjorie B. Zucker and Walter Troll and Sidney Belman The Tumor-Promoter Phorbol Ester (12-$0$-Tetradecanoyl-Phorbol-$ 13$-Acetate), a Potent Aggregating Agent for Blood Platelets . . . . . . . . . . 325 Larry Sellers and Daryl Granner Regulation of Tyrosine Aminotransferase Activity in Two Liver-Derived Permanent Cell Lines . . . . . . . . . . . . . . . 337 Marijke E. Holtrop and Lawrence G. Raisz and Hollis A. Simmons The Effects of Parathyroid Hormone, Colchicine, and Calcitonin on the Ultrastructure and the Activity of Osteoclasts in Organ Culture . . . . . . 346 Lawrence R. Gurley and Ronald A. Walters and Robert A. Tobey Cell Cycle-Specific Changes in Histone Phosphorylation Associated with Cell Proliferation and Chromosome Condensation . . . . . . . . . . . . . . 356 Joseph J. Pysh and Ronald G. Wiley Synaptic Vesicle Depletion and Recovery in Cat Sympathetic Ganglia Electrically Stimulated in Vivo . . . . . . . . . . . 365 Yusuf Kapanci and André Assimacopoulos and Claude Irle and André Zwahlen and Giulio Gabbiani ''Contractile Interstitial Cells'' in Pulmonary Alveolar Septa: a Possible Regulator of Ventilation\slash Perfusion Ratio? . . . . . . . . . . . . . . . . . 375 Richard G. W. Anderson Isolation of Ciliated Or Unciliated Basal Bodies from the Rabbit Oviduct . . 393 Samuel B. Horowitz and Leonard C. Moore The Nuclear Permeability, Intracellular Distribution, and Diffusion of Inulin in the Amphibian Oocyte . . . . . . . . . . 405 G. P. M. Moore and Sue Lintern-Moore and Hannah Peters and M. Faber RNA Synthesis in the Mouse Oocyte . . . 416 Richard Rodewald and Morris J. Karnovsky Porous Substructure of the Glomerular Slit Diaphragm in the Rat and Mouse . . 423 Leighton P. Everhart and Robert W. Rubin Cyclic Changes in the Cell Surface . . . 434 Leighton P. Everhart and Robert W. Rubin Cyclic Changes in the Cell Surface . . . 442 Thomas M. O'Connor and Charles R. Wyttenbach Cell Death in the Embryonic Chick Spinal Cord . . . . . . . . . . . . . . . . . . 448 David H. DeHeer and Merle S. Olson and R. Neal Pinckard Characterization of Rat Liver Subcellular Membranes . . . . . . . . . 460 Harry L. Malech and Thomas L. Lentz Microfilaments in Epidermal Cancer Cells 473 Richard N. Trelease and Wayne M. Becker and John J. Burke Cytochemical Localization of Malate Synthase in Glyoxysomes . . . . . . . . 483 Jason Wolfe and Lewis Rodriguez Inhibition of Nuclear Reconstruction by Dithiothreitol . . . . . . . . . . . . . 497 G. Giménez-Martín and C. de la Torre and M. E. Fernández-Gómez and A. González-Fernández Experimental Analysis of Nucleolar Reorganization . . . . . . . . . . . . . 502 M. Johan Broekman and Nelson P. Westmoreland and Phin Cohen An Improved Method for Isolating Alpha Granules and Mitochondria from Human Platelets . . . . . . . . . . . . . . . 507 Fred R. Butcher and Rose H. Goldman Effect of cytochalasin B and colchicine on $ \alpha $-amylase release from rat parotid tissue slices . . . . . . . . . 519 Phillip N. Dean and James H. Jett Mathematical Analysis of DNA Distributions Derived from Flow Microfluorometry . . . . . . . . . . . . 523
Siegfried W. de Laat and John G. Bluemink New Membrane Formation During Cytokinesis in Normal and Cytochalasin B-Treated Eggs of \bionameXenopus Laevis 529 John R. Feagler and Thomas W. Tillack and David D. Chaplin and Philip W. Majerus The Effects of Thrombin on Phytohemagglutinin Receptor Sites in Human Platelets . . . . . . . . . . . . 541 Christine Kent and M. A. Williams The Nature of Hypothalamo-Neurohypophyseal Neurosecretion in the Rat . . . . . . . 554 Phyllis R. Strauss Effects of Serum on Membrane Transport 571 J. S. Frank and G. A. Langer The Myocardial Interstitium: Its Structure and Its Role in Ionic Exchange 586 M. S. Forbes and N. Sperelakis Spheroidal Bodies in the Junctional Sarcoplasmic Reticulum of Lizard Myocardial Cells . . . . . . . . . . . . 602 Gert Kreibich and Ann L. Hubbard and David D. Sabatini On the Spatial Arrangement of Proteins in Microsomal Membranes from Rat Liver 616 Jean-Jacques Curgy and Gérard Ledoigt and Barbara J. Stevens and Jean André Mitochondrial and Cytoplasmic Ribosomes from \bionameTetrahymena Pyriformis . . 628 Joris J. Deman and Erik A. Bruyneel and Marc M. Mareel A Study on the Mechanism of Intercellular Adhesion . . . . . . . . . 641 Akitsugu Saito and Murray Smigel and Sidney Fleischer Membrane Junctions in the Intermembrane Space of Mitochondria from Mammalian Tissues . . . . . . . . . . . . . . . . 653 James E. Vaughn and Charles K. Henrikson and Judith A. Grieshaber A Quantitative Study of Synapses on Motor Neuron Dendritic Growth Cones in Developing Mouse Spinal Cord . . . . . . 664 Michael A. Gimbrone and Ramzi S. Cotran and Judah Folkman Human Vascular Endothelial Cells in Culture . . . . . . . . . . . . . . . . 673 C. R. Scheid and I. A. Macchi Monolayer Cultures Derived from Neonatal Hamster Pancreas . . . . . . . . . . . . 685 F. C. Steward and H. W. Israel and M. M. Salpeter The Labeling of Cultured Cells of \bionameAcer with [$^{14}$C]Proline and Its Significance . . . . . . . . . . . . 695 Hans Ris and Donna F. Kubai An Unusual Mitotic Mechanism in the Parasitic Protozoan Syndinium Sp . . . . 702 Peter M. Leuenberger and Alex B. Novikoff Localization of Transport Adenosine Triphosphatase in Rat Cornea . . . . . . 721 Brenda R. Eisenberg and Aileen M. Kuda and James B. Peter Stereological Analysis of Mammalian Skeletal Muscle . . . . . . . . . . . . 732 Jonas B. Galper Mitochondrial Protein Synthesis in HeLa Cells . . . . . . . . . . . . . . . . . 755 Douglas M. Gersten and Thomas W. Kimmerer and H. Bruce Bosmann The Lysosome Periphery: Biochemical and Electrokinetic Properties of the Tritosome Surface . . . . . . . . . . . 764 James H. Martin and Freida L. Carson and George J. Race Calcium-Containing Platelet Granules . . 775 Robert M. Singer and William H. Fishman Characterization of Two HeLa Sublines: Tcrc-1 Produces Regan Isoenzyme and Tcrc-2, Non-Regan Isoenzyme . . . . . . 777 C. A. Sprague and H. Hoehn and G. M. Martin Ploidy of Living Clones of Human Somatic Cells Determined by Mensuration at Metaphase . . . . . . . . . . . . . . . 781 James R. LaFountain Microfilaments in Spermatocytes of Nephrotoma Suturalis . . . . . . . . . . 784 James K. Koehler and William D. Perkins Fine Structure Observations on the Distribution of Antigenic Sites on Guinea Pig Spermatozoa . . . . . . . . . 789 Harold C. Slavkin and Gary N. Trump and Virginia Mansour and Pamela Matosian and William G. Mino Localization of H-2 Histocompatibility Alloantigens on Mouse Embryonic Tooth Epithelial and Mesenchymal Cell Surfaces 795
J. Meldolesi Dynamics of Cytoplasmic Membranes in Guinea Pig Pancreatic Acinar Cells . . . 1 Katsuro Koike and David R. Wolstenholme Evidence for Discontinuous Replication of Circular Mitochondrial DNA Molecules from Novikoff Rat Ascites Hepatoma Cells 14 Allen W. Schuetz and Robin A. Wallace and James N. Dumont Steroid Inhibition of Protein Incorporation by Isolated Amphibian Oocytes . . . . . . . . . . . . . . . . 26 Saul Kit and Wai-Choi Leung Genetic Control of Mitochondrial Thymidine Kinase in Human-Mouse and Monkey-Mouse Somatic Cell Hybrids . . . 35 Nathan A. Berger and Sister Ann Marie Skinner Characterization of Lymphocyte Transformation Induced by Zinc Ions . . 45 Paul C. Letourneau and Norman K. Wessells Migratory Cell Locomotion Versus Nerve Axon Elongation . . . . . . . . . . . . 56 Thomas E. Ukena and Joan Z. Borysenko and Morris J. Karnovsky and Richard D. Berlin Effects of Colchicine, Cytochalasin B, and $2$-Deoxyglucose on the Topographical Organization of Surface-Bound Concanavalin a in Normal and Transformed Fibroblasts . . . . . . 70 J. Vergara and F. Zambrano and J. D. Robertson and H. Elrod Isolation and Characterization of Luminal Membranes from Urinary Bladder 83 R. Blair Evans and Vera Morhenn and Albert L. Jones and Gordon M. Tomkins Concomitant Effects of Insulin on Surface Membrane Conformation and Polysome Profiles of Serum-Starved Balb/c 3T3 Fibroblasts . . . . . . . . . 95 Camillo Peracchia Excitable Membrane Ultrastructure . . . 107 M. J. Connock and P. R. Kirk and A. P. Sturdee A Zonal Rotor Method for the Preparation of Microperoxisomes from Epithelial Cells of Guinea Pig Small Intestine . . 123 Martin A. Gorovsky and Josephine Bowen Keevert and Gloria Lorick Pleger Histone F1 of \bionameTetrahymena Macronuclei . . . . . . . . . . . . . . 134 D. E. Hillman and R. Llins Calcium-Containing Electron-Dense Structures in the Axons of the Squid Giant Synapse . . . . . . . . . . . . . 146 J. L. Oschman and T. A. Hall and P. D. Peters and B. J. Wall Association of Calcium with Membranes of Squid Giant Axon . . . . . . . . . . . . 156 J. R. McIntosh Bridges Between Microtubules . . . . . . 166 Henri Beaufay and Alain Amar-Costesec and Ernest Feytmans and Denise Thin\`es-Sempoux and Maurice Wibo and Mariette Robbi and Jacques Berthet Analytical Study of Microsomes and Isolated Subcellular Membranes from Rat Liver . . . . . . . . . . . . . . . . . 188 Alain Amar-Costesec and Henri Beaufay and Maurice Wibo and Denise Thin\`es-Sempoux and Ernest Feytmans and Mariette Robbi and Jacques Berthet Analytical Study of Microsomes and Isolated Subcellular Membranes from Rat Liver . . . . . . . . . . . . . . . . . 201 Henri Beaufay and Alain Amar-Costesec and Denise Thin\`es-Sempoux and Maurice Wibo and Mariette Robbi and Jacques Berthet Analytical Study of Microsomes and Isolated Subcellular Membranes from Rat Liver . . . . . . . . . . . . . . . . . 213 L. W. Roti Roti and A. R. Stevens Effect of $5$-Bromodeoxyuridine on Growth, Encystment, and Excystment of \bionameAcanthamoeba Castellanii . . . . 233 José Remacle and Stanley Fowler and Henri Beaufay and Jacques Berthet Ultrastructural localization of cytochrome B$_5$ on rat liver microsomes by means of hybrid antibodies labeled with ferritin . . . . . . . . . . . . . 237 Nehama Zakai and Abraham Loyter and Richard G. Kulka Fusion of Erythrocytes and Other Cells with Retention of Erythrocyte Cytoplasm 241 Lorraine F. Meisner and Thomas W. Chuprevich and Stanley L. Inhorn and Collin B. Johnson Dye-Nucleoprotein Interactions in Giemsa Banding . . . . . . . . . . . . . . . . 248 Guy A. Thompson and Lonnie C. Baugh and Laurie F. Walker Nonlethal Deciliation of \bionameTetrahymena by a Local Anesthetic and Its Utility As a Tool for Studying Cilia Regeneration . . . . . . 253 G. H. Weber and U. Heine and M. Cottler-Fox and G. Beaudreau Direct Visualization of Labeled Nucleotides in DNA Using Electron Microscopy and Autoradiography . . . . . 257 Eric Schabtach and Terry A. Parkening A Method for Sequential High Resolution Light and Electron Microscopy of Selected Areas of the Same Material . . 261
Robert P. Bolender Stereological Analysis of the Guinea Pig Pancreas . . . . . . . . . . . . . . . . 269 Michael L. Higgins and Lolita Daneo-Moore Factors Influencing the Frequency of Mesosomes Observed in Fixed and Unfixed Cells of Streptococcus Faecalis . . . . 288 Chung-Ho Chen and John W. Greenawalt and Albert L. Lehninger Biochemical and Ultrastructural Aspects of Ca$^{2+}$ Transport by Mitochondria of the Hepatopancreas of the Blue Crab \bionameCallinectes Sapidus . . . . . . 301 Gerald L. Becker and Chung-Ho Chen and John W. Greenawalt and Albert L. Lehninger Calcium Phosphate Granules in the Hepatopancreas of the Blue Crab Callinectes Sapidus . . . . . . . . . . 316 Carol Bibb and Richard W. Young Renewal of Fatty Acids in the Membranes of Visual Cell Outer Segments . . . . . 327 Jarnardan K. Reddy and Daniel L. Azarnoff and Donald J. Svoboda and Jada D. Prasad Nafenopin-Induced Hepatic Microbody (Peroxisome) Proliferation and Catalase Synthesis in Rats and Mice . . . . . . . 344 Clifford A. Lingwood and D. Brian Thomas Rapid Changes in Nucleoside Transport Induced by Growth Inhibitors . . . . . . 359 D. A. Newsome and R. T. Fletcher and W. G. Robison and K. R. Kenyon and G. J. Chader Effects of Cyclic AMP and Sephadex Fractions of Chick Embryo Extract on Cloned Retinal Pigmented Epithelium in Tissue Culture . . . . . . . . . . . . . 369 William B. Upholt and Piet Borst Accumulation of Replicative Intermediates of Mitochondrial DNA in \bionameTetrahymena Pyriformis Grown in Ethidium Bromide . . . . . . . . . . . . 383 David Schubert and A. John Harris and Carrick E. Devine and Stephen Heinemann Characterization of a Unique Muscle Cell Line . . . . . . . . . . . . . . . . . . 398 Robert S. Hikida and Joseph A. Lombardo Regeneration of Pigeon Fast and Slow Muscle Fiber Types After Partial Excision and Mincing . . . . . . . . . . 414 Itzhak Binderman and Dan Duksin and Arieh Harell and Ephraim Katzir (Katchalski) and Leo Sachs Formation of Bone Tissue in Culture from Isolated Bone Cells . . . . . . . . . . 427 C. Peter Wolk and Sam M. Austin and John Bortins and Aaron Galonsky Autoradiographic Localization Of $^{13}$N After Fixation Of $^{13}$N-Labeled Nitrogen Gas by a Heterocyst-Forming Blue--Green Alga . . 440 Dorothy A. Schlaeger and Morton S. Fuchs and Suk-Hee Kang Ecdysone-Mediated Stimulation of Dopa Decarboxylase Activity and Its Relationship to Ovarian Development in Aedes Aegypti . . . . . . . . . . . . . 454 Ursula Bretz and Marco Baggiolini and Rolf Hauser and Christian Hodel Resolution of Three Distinct Populations of Nerve Endings from Rat Brain Homogenates by Zonal Isopycnic Centrifugation . . . . . . . . . . . . . 466 Armand F. Miranda and Gabriel C. Godman and Arline D. Deitch and Stuart W. Tanenbaum Action of Cytochalasin D on Cells of Established Lines . . . . . . . . . . . 481 Clara Franzini-Armstrong Freeze Fracture of Skeletal Muscle from the Tarantula Spider . . . . . . . . . . 501 David L. Brown and G. Benjamin Bouck Microtubule Biogenesis and Cell Shape in Ochromonas . . . . . . . . . . . . . . . 514 Gordon I. Kaye and Cecilia M. Fenoglio and Frank B. Hoefle and Jorge Fischbarg Studies on the Cornea . . . . . . . . . 537 Walter L. Davis and David B. P. Goodman and James H. Martin and James L. Matthews and Howard Rasmussen Vasopressin-Induced Changes in the Toad Urinary Bladder Epithelial Surface . . . 544 J. H. M. Temmink and H. Spiele Ruthenium Red Staining of Normal and Transformed Murine Fibroblasts in Vitro 548 C. Walig and J. M. M. Walboomers and J. van der Noordaa Ultrastructural Localization of Concanavalin a Receptors in Somatic Cell Hybrids Between Normal Mouse Cells and Simian Virus $ 40$-Transformed Rat Cells 553 Daniel A. Goodenough Bulk Isolation of Mouse Hepatocyte Gap Junctions . . . . . . . . . . . . . . . 557
Gary W. Grimes and Henry R. Mahler and Philip S. Perlman Nuclear Gene Dosage Effects on Mitochondrial Mass and DNA . . . . . . . 565 Daniel A. Goodenough and Norton B. Gilula The Splitting of Hepatocyte Gap Junctions and Zonulae Occludentes with Hypertonic Disaccharides . . . . . . . . 575 Joan Smith-Sonneborn and Michael Klass Changes in the DNA Synthesis Pattern of Paramecium with Increased Clonal Age and Interfission Time . . . . . . . . . . . 591 Robert S. Decker Lysosomal Packaging in Differentiating and Degenerating Anuran Lateral Motor Column Neurons . . . . . . . . . . . . . 599 Frank Slaby and Carolyn Brown Changes in the Ribosome Content, Principal Microsomal Protein Composition, and Secretory Character of Mammary Epithelial Rough Endoplasmic Reticulum During Differentiation . . . . 613 Frank Wunderlich and Werner Batz and Volker Speth and Donald F. H. Wallach Reversible, Thermotropic Alteration of Nuclear Membrane Structure and Nucleocytoplasmic RNA Transport in \bionameTetrahymena . . . . . . . . . . 633 Jacques Padawer Identification of Mast Cells in the Scanning Electron Microscope by Means of X-Ray Spectrometry . . . . . . . . . . . 641 Richard T. Ambron and James E. Goldman and Elizabeth Barnes Thompson and James H. Schwartz Synthesis of Glycoproteins in a Single Identified Neuron of \bionameAplysia Californica . . . . . . . . . . . . . . 649 Richard T. Ambron and James E. Goldman and James H. Schwartz Axonal Transport of Newly Synthesized Glycoproteins in a Single Identified Neuron of \bionameAplysia Californica 665 Barbara Anne Wolf and P. W. Robbins Cell Mitotic Cycle Synthesis of Nil Hamster Glycolipids Including the Forssman Antigen . . . . . . . . . . . . 676 R. E. Jones and A. A. Moscona Effects of Cytosine Arabinoside on Differential Gene Expression in Embryonic Neural Retina . . . . . . . . 688 J. Metuzals and W. E. Mushynski Electron Microscope and Experimental Investigations of the Neurofilamentous Network in Deiters' Neurons . . . . . . 701 A. P. Somlyo and A. V. Somlyo and C. E. Devine and P. D. Peters and T. A. Hall Electron Microscopy and Electron Probe Analysis of Mitochondrial Cation Accumulation in Smooth Muscle . . . . . 723 E. R. Phillips and J. F. Perdue Ultrastructural Distribution of Cell Surface Antigens in Avian Tumor Virus-Infected Chick Embryo Fibroblasts 743 Douglas B. Murphy and Lewis G. Tilney The Role of Microtubules in the Movement of Pigment Granules in Teleost Melanophores . . . . . . . . . . . . . . 757 R. T. L. Chan and I. E. Scheffler Isopycnic Centrifugation of Chromatin in Renografin Solutions . . . . . . . . . . 780 Gert Kreibich and David D. Sabatini Selective Release of Content from Microsomal Vesicles Without Membrane Disassembly . . . . . . . . . . . . . . 789 David Lagunoff and Helen Wan Temperature Dependence of Mast Cell Histamine Secretion . . . . . . . . . . 809 Anders Edström. Effects of Ca$^{2+}$ and Mg$^{2+}$ on Rapid Axonal Transport of Proteins in Vitro in Frog Sciatic Nerves . . . . . . 812 Alberto L. Politoff and Steven Rose and George D. Pappas The Calcium Binding Sites of Synaptic Vesicles of the Frog Sartorius Neuromuscular Junction . . . . . . . . . 818 H. L. Leffert and S. Sell Alpha$_1$-Fetoprotein Biosynthesis During the Growth Cycle of Differentiated Fetal Rat Hepatocytes in Primary Monolayer Culture . . . . . . . 823 Ole Frederiksen and Jòrgen Rostgaard Absence of Dilated Lateral Intercellular Spaces in Fluid-Transporting Frog Gallbladder Epithelium . . . . . . . . . 830
Theodore L. Steck The Organization of Proteins in the Human Red Blood Cell Membrane . . . . . 1 Kou M. Hwang and Linda C. Yang and Christine K. Carrico and Rose A. Schulz and John B. Schenkman and Alan C. Sartorelli Production of Membrane Whorls in Rat Liver by Some Inhibitors of Protein Synthesis . . . . . . . . . . . . . . . 20 Robert S. Decker and Daniel S. Friend Assembly of Gap Junctions During Amphibian Neurulation . . . . . . . . . 32 J. R. Smith and L. Hayflick Variation in the Life-Span of Clones Derived from Human Diploid Cell Strains 48 V. T. Nachmias Properties of \bionamePhysarum Myosin Purified by a Potassium Iodide Procedure 54 Marie Kopecká and H. J. Phaff and G. H. Fleet Demonstration of a Fibrillar Component in the Cell Wall of the Yeast \bionameSaccharomyces Cerevisiae and Its Chemical Nature . . . . . . . . . . . . 66 L. Boquist and B. Hellman and Å. Lernmark and I.-B. Täljedal Influence of the Mutation ``Diabetes'' on Insulin Release and Islet Morphology in Mice of Different Genetic Backgrounds 77 O. Stein and L. Sanger and Y. Stein Colchicine-Induced Inhibition of Lipoprotein and Protein Secretion into the Serum and Lack of Interference with Secretion of Biliary Phospholipids and Cholesterol by Rat Liver in Vivo . . . . 90 Yoshitaka Obara and Lee S. Chai and Herbert Weinfeld and Avery A. Sandberg Prophasing of Interphase Nuclei and Induction of Nuclear Envelopes Around Metaphase Chromosomes in HeLa and Chinese Hamster Homo- and Heterokaryons 104 D. J. Kemp and P. Y. Dyer and G. E. Rogers Keratin Synthesis During Development of the Embryonic Chick Feather . . . . . . 114 Wu-Nan Wen and Pedro E. León and Donald R. Hague Multiple Gene Sites for 5S and 18 + 28S RNA on Chromosomes of Glyptotendipes Barbipes (Staeger) . . . . . . . . . . . 132 Joanne S. Ingwall and Cynthia D. Weiner and Manuel F. Morales and Elaine Davis and Frank E. Stockdale Specificity of Creatine in the Control of Muscle Protein Synthesis . . . . . . 145 G. L. Kimmel and F. G. Péron and A. Haksar and E. Bedigian and W. F. Robidoux and M. T. Lin Ultrastructure, Steroidogenic Potential, and Energy Metabolism of the Snell Adrenocortical Carcinoma 494 . . . . . . 152 Ilona Staprans and Ellen Roter Dirksen Microtubule Protein During Ciliogenesis in the Mouse Oviduct . . . . . . . . . . 164 Shinya Inoué and Gary G. Borisy and Daniel P. Kiehart Growth and Lability of \bionameChaetopterus Oocyte Mitotic Spindles Isolated in the Presence of Porcine Brain Tubulin . . . . . . . . . 175 Georges Pelletier Autoradiographic Studies of Synthesis and Intracellular Migration of Glycoproteins in the Rat Anterior Pituitary Gland . . . . . . . . . . . . 185 Albert DiPasquale and Paul B. Bell The Upper Cell Surface: Its Inability to Support Active Cell Movement in Culture 198 A. G. Gambarini and F. J. S. Lara Under-Replication of Ribosomal Cistrons in Polytene Chromosomes of Rhynchosciara 215 T. L. Spray and R. A. Waugh and J. R. Sommer Peripheral Couplings in Adult Vertebrate Skeletal Muscle . . . . . . . . . . . . 223 J. J. McCormick Physical Separation of Nuclei from Two Independent Plasmodia of \bionamePhysarum Polycephalum After Fusion . . . . . . . . . . . . . . . . . 227 Daniel W. McKeel and Leonard Jarett The Enrichment of Adenylate Cyclase in the Plasma Membrane and Golgi Subcellular Fractions of Porcine Adenohypophysis . . . . . . . . . . . . 231 C. W. Cotman and D. Taylor Localization and Characterization of Concanavalin a Receptors in the Synaptic Cleft . . . . . . . . . . . . . . . . . 236 John N. Howell Intracellular Binding of Ruthenium Red in Frog Skeletal Muscle . . . . . . . . 242 Brian Storrie Effect of Dibutyryl Adenosine Cyclic 3',5'-Monophosphate and Testololactone on Concanavalin a Binding and Cell Killing . . . . . . . . . . . . . . . . 247
Lily Yeh Jan and Jean-Paul Revel Ultrastructural Localization of Rhodopsin in the Vertebrate Retina . . . 257 Peggy R. Hudson and J. Robert Waaland Ultrastructure of Mitosis and Cytokinesis in the Multinucleate Green Alga Acrosiphonia . . . . . . . . . . . 274 Susannah T. Rohrlich Fine Structural Demonstration of Ordered Arrays of Cytoplasmic Filaments in Vertebrate Iridophores . . . . . . . . . 295 M. P. Siegers and J. C. Schaer and H. Hirsiger and R. Schindler Determination of Rates of DNA Synthesis in Cultured Mammalian Cell Populations 305 Anne E. Lykkesfeldt and H. A. Andersen The Effect of $5$-Bromodeoxyuridine on DNA Replication and Cell Division in \bionameTetrahymena Pyriformis . . . . . 316 M. E. J. Holwill and Patricia D. Peters Dynamics of the Hispid Flagellum of Ochromonas Danica . . . . . . . . . . . 322 Marilynn E. Etzler and Margaret L. Branstrator Differential Localization of Cell Surface and Secretory Components in Rat Intestinal Epithelium by Use of Lectins 329 James B. Wade and Morris J. Karnovsky Fracture Faces of Osmotically Disrupted Zonulae Occludentes . . . . . . . . . . 344 Graeme B. Ryan and Joan Z. Borysenko and Morris J. Karnovsky Factors Affecting the Redistribution of Surface-Bound Concanavalin a on Human Polymorphonuclear Leukocytes . . . . . . 351 Gary R. Gunther and John L. Wang and Gerald M. Edelman The Kinetics of Cellular Commitment During Stimulation of Lymphocytes by Lectins . . . . . . . . . . . . . . . . 366 Carol Bibb and Richard W. Young Renewal of Glycerol in the Visual Cells and Pigment Epithelium of the Frog Retina . . . . . . . . . . . . . . . . . 378 H. Paul Ehrlich and Russell Ross and Paul Bornstein Effects of Antimicrotubular Agents on the Secretion of Collagen . . . . . . . 390 Armand F. Miranda and Gabriel C. Godman and Stuart W. Tanenbaum Action of Cytochalasin D on Cells of Established Lines . . . . . . . . . . . 406 J. B. Tucker Microtubule Arms and Cytoplasmic Streaming and Microtubule Bending and Stretching of Intertubule Links in the Feeding Tentacle of the Suctorian Ciliate Tokophrya . . . . . . . . . . . 424 Richard O. Hynes and Kenneth C. Humphryes Characterization of the External Proteins of Hamster Fibroblasts . . . . 438 Andrew Churg and Winston A. Anderson Induction of Endometrial Peroxidase Synthesis and Secretion by Estrogen and Estrogen Antagonist . . . . . . . . . . 449 Marvin R. Kalt and Joseph G. Gall Observations on Early Germ Cell Development and Premeiotic Ribosomal DNA Amplification in \bionameXenopus Laevis 460 Carol A. Sattler and L. Andrew Staehelin Ciliary Membrane Differentiations in \bionameTetrahymena Pyriformis . . . . . 473 William P. Cunningham and L. Andrew Staehelin and Robert W. Rubin and Ross Wilkins and Mary Bonneville Effects of Phosphotungstate Negative Staining on the Morphology of the Isolated Golgi Apparatus . . . . . . . . 491 L. de Meis and W. Hasselbach and R. D. Machado Characterization of Calcium Oxalate and Calcium Phosphate Deposits in Sarcoplasmic Reticulum Vesicles . . . . 505 Hiroshi Nogami and Marshall R. Urist Substrata Prepared from Bone Matrix for Chondrogenesis in Tissue Culture . . . . 510 M. Kagayama and W. W. Douglas Electron Microscope Evidence of Calcium-Induced Exocytosis in Mast Cells Treated with 48/80 Or the Ionophores A-23187 and X-537A . . . . . . . . . . . 519 J. B. Rattner and Michael W. Berns Light and Electron Microscopy of Laser Microirradiated Chromosomes . . . . . . 526 Blair Bowers and Edward D. Korn Localization of Lipophosphonoglycan on Both Sides of \bionameAcanthamoeba Plasma Membrane . . . . . . . . . . . . 533 Ephraim Yavin and Ziva Yavin Attachment and Culture of Dissociated Cells from Rat Embryo Cerebral Hemispheres on Polylysine-Coated Surface 540 Samuel A. Latt Detection of DNA Synthesis in Interphase Nuclei by Fluorescence Microscopy . . . 546 Takami Oka and John W. Perry and Yale J. Topper Changes in Insulin Responsiveness During Development of Mammary Epithelium . . . 550 Richard L. Wood A Closely Packed Array of Membrane Intercalated Particles at the Free Surface of Hydra . . . . . . . . . . . . 556 Georgirene D. Vladutiu and Noel R. Rose Intracellular Distribution of a Primate-Specific Esterase in Cultured Cells and Tissues . . . . . . . . . . . 560 David R. Burgess and Robert D. Grey Alterations in Morphology of Developing Microvilli Elicited by Cytochalasin B 566 M. Borgers and S. de Nollin The Preservation of Subcellular Organelles of Candida Albicans with Conventional Fixatives . . . . . . . . . 574
Massimo Olivotto and Francesco Paoletti Protein Metabolism in Tumor Cells at Various Stages of Growth in Vivo . . . . 585 John I. Gallin and Alan S. Rosenthal The Regulatory Role of Divalent Cations in Human Granulocyte Chemotaxis . . . . 594 Michael D. Gershon and Martin Hagopian and Eladio A. Nunez An Electron Microscope Autoradiographic Study of the Neuronal and Extraneuronal Localization of Labeled Amine in the Heart of the Bat After Administration of Tritiated Norepinephrine . . . . . . . . 610 John L. Skosey and Evelyn Damgaard and Donald Chow and Leif B. Sorensen Modification of Zymosan-Induced Release of Lysosomal Enzymes from Human Polymorphonuclear Leukocytes by Cytochalasin B . . . . . . . . . . . . . 625 Joan A. Higgins Studies on the Biogenesis of Smooth Endoplasmic Reticulum Membranes in Hepatocytes of Phenobarbital-Treated Rats . . . . . . . . . . . . . . . . . . 635 Stanton G. Axline and Eve P. Reaven Inhibition of Phagocytosis and Plasma Membrane Mobility of the Cultivated Macrophage by Cytochalasin B . . . . . . 647 Robert A. Bloodgood and Kenneth R. Miller Freeze-Fracture of Microtubules and Bridges in Motile Axostyles . . . . . . 660 George H. Goetz and Pamela L. Johnston and Kathy Dobrosielski-Vergona and Edgar F. Carell Vitamin B$_{12}$ and the Macromolecular Composition of Euglena . . . . . . . . . 672 S. Knutton and A. R. Limbrick and J. D. Robertson Regular Structures in Membranes . . . . 679 Michael Durphy and Paul N. Manley and Errol C. Friedberg A Demonstration of Several Deoxyribonuclease Activities in Mammalian Cell Mitochondria . . . . . . 695 Charles T. Roberts and Eduardo Orias On the Mechanism of Adaptation to Protein Synthesis Inhibitors by \bionameTetrahymena . . . . . . . . . . 707 Alain Amar-Costesec and Maurice Wibo and Denise Thin\`es-Sempoux and Henri Beaufay and Jacques Berthet Analytical Study of Microsomes and Isolated Subcellular Membranes from Rat Liver . . . . . . . . . . . . . . . . . 717 Robert Peter Aaronson and Günter Blobel On the Attachment of the Nuclear Pore Complex . . . . . . . . . . . . . . . . 746 Jack Rosenbluth Substructure of Amphibian Motor End Plate . . . . . . . . . . . . . . . . . 755 H. L. Leffert Growth Control of Differentiated Fetal Rat Hepatocytes in Primary Monolayer Culture . . . . . . . . . . . . . . . . 767 K. Koch and H. L. Leffert Growth Control of Differentiated Fetal Rat Hepatocytes in Primary Monolayer Culture . . . . . . . . . . . . . . . . 780 H. L. Leffert Growth Control of Differentiated Fetal Rat Hepatocytes in Primary Monolayer Culture . . . . . . . . . . . . . . . . 792 Martha E. Fedorko Loss of Iron from Mouse Peritoneal Macrophages in Vitro After Uptake of [$^{55}$ Fe]Ferritin and [$^{55}$ Fe]Ferritin Rabbit Antiferritin Complexes . . . . . . . . . . . . . . . 802 Robert L. Trelstad and Kimiko Hayashi and Bryan P. Toole Epithelial Collagens and Glycosaminoglycans in the Embryonic Cornea . . . . . . . . . . . . . . . . . 815 George K. Chacko and David E. Goldman and Harish C. Malhotra and Maynard M. Dewey Isolation and Characterization of Plasma Membrane Fractions from Garfish Lepisosteus Osseus Olfactory Nerve . . . 831 Thomas L. Rothstein and J. J. Blum Lysosomal Physiology in \bionameTetrahymena . . . . . . . . . . 844 W. Kleinow and W. Neupert and F. Miller Electron Microscope Study of Mitochondrial 60S and Cytoplasmic 80S Ribosomes from Locusta Migratoria . . . 860 A. Carabez and F. Sandoval A mitochondrial inner membrane preparation that sediments at 100 $g$ 877 D. Huang Effect of Extracellular Chondroitin Sulfate on Cultured Chondrocytes . . . . 881 Joseph M. Harb and D. Eugene Copeland Helical Form Cristae in the Mitochondria of the Pseudobranch of Cyprinodon Variegatus Adapted to Conditions of Constant Light and Darkness . . . . . . 886 Elizabeth D. Hay and Stephen Meier Glycosaminoglycan Synthesis by Embryonic Inductors: Neural Tube, Notochord, and Lens . . . . . . . . . . . . . . . . . . 889 Ellen Roter Dirksen Ciliogenesis in the Mouse Oviduct . . . 899 Warren M. Pulich Resistance to High Oxygen Tension, Streptonigrin, and Ultraviolet Irradiation in the Green Alga Chlorella Sorokiniana Strain Ors . . . . . . . . . 904 M. Kumegawa and T. Nakamura and T. Yamada Studies on the Effect of Selective Membrane Filtration on the Differentiation of Tissue Cultures . . . 908 David M. Phillips Nuclear Shaping in the Absence of Microtubules in Scorpion Spermatids . . 911 Beverly H. Bergstrom and John M. Arnold Nonkinetochore Association of Chromatin and Microtubules . . . . . . . . . . . . 917
Hava Peretz and Zivia Toister and Yehudith Laster and Abraham Loyter Fusion of Intact Human Erythrocytes and Erythrocyte Ghosts . . . . . . . . . . . 1 Jean-Claude Antoine and Stratis Avrameas and Nicholas K. Gonatas and Anna Stieber and Jacqueline O. Gonatas Plasma Membrane and Internalized Immunoglobulins of Lymph Node Cells Studied with Conjugates of Antibody Or Its Fab Fragments with Horseradish Peroxidase . . . . . . . . . . . . . . . 12 Melvin P. Garber and Peter L. Steponkus Identification of Chloroplast Coupling Factor by Freeze-Etching and Negative-Staining Techniques . . . . . . 24 Fred D. Warner and Peter Satir The Structural Basis of Ciliary Bend Formation . . . . . . . . . . . . . . . 35 Robert Narotzky and William Bondareff Biogenic Amines in Cultured Neuroblastoma and Astrocytoma Cells . . 64 Lloyd A. Culp Substrate-Attached Glycoproteins Mediating Adhesion of Normal and Virus-Transformed Mouse Fibroblasts . . 71 Ronald A. Coss and Jeremy D. Pickett-Heaps The Effects of Isopropyl N-Phenyl Carbamate on the Green Alga \bionameOedogonium Cardiacum . . . . . . 84 William B. Winborn and Leonard L. Seelig Pattern of Osmium Deposition in the Parietal Cells of the Stomach . . . . . 99 Dominic K. Yip and Nelly Auersperg Structural and Functional Heterogeneity of the Surface of Rat Leukemia Cells . . 109 Robert S. Rew and Howard J. Saz Enzyme Localization in the Anaerobic Mitochondria of Ascaris Lumbricoides . . 125 James P. Whitlock and Haruko Miller and Harry V. Gelboin Induction of aryl hydrocarbon (benzo[a]pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture . . . . . . . . . . . . 136 Lloyd Matsumoto and Harumi Kasamatsu and Lajos Pikó and Jerome Vinograd Mitochondrial DNA Replication in Sea Urchin Oocytes . . . . . . . . . . . . . 146 Elizabeth H. Harris and John E. Boynton and Nicholas W. Gillham Chloroplast Ribosome Biogenesis in Chlamydomonas . . . . . . . . . . . . . 160 Karl H. Pfenninger and Richard P. Bunge Freeze-Fracturing of Nerve Growth Cones and Young Fibers . . . . . . . . . . . . 180 Antti Penttila and Hannu Kalimo and Benjamin F. Trump Influence of Glutaraldehyde And/Or Osmium Tetroxide on Cell Volume, Ion Content, Mechanical Stability, and Membrane Permeability of Ehrlich Ascites Tumor Cells . . . . . . . . . . . . . . 197 Philip B. Dunham and Ira M. Goldstein and Gerald Weissmann Potassium and Amino Acid Transport in Human Leukocytes Exposed to Phagocytic Stimuli . . . . . . . . . . . . . . . . 215 Wojciech Sawicki and Jan Rowínski and Jan Abramczuk Image Analysis of Chromatin in Cells of Preimplantation Mouse Embryos . . . . . 227 David F. Albertini and Everett Anderson The Appearance and Structure of Intercellular Connections During the Ontogeny of the Rabbit Ovarian Follicle with Particular Reference to Gap Junctions . . . . . . . . . . . . . . . 234 Ursula Bretz and Marco Baggiolini Biochemical and Morphological Characterization of Azurophil and Specific Granules of Human Neutrophilic Polymorphonuclear Leukocytes . . . . . . 251 Nina Strömgren Allen Endoplasmic Filaments Generate the Motive Force for Rotational Streaming in Nitella . . . . . . . . . . . . . . . . 270 Mark C. Willingham and Ira Pastan Cyclic AMP Mediates the Concanavalin a Agglutinability of Mouse Fibroblasts . . 288 Richard A. Miller and Frank H. Ruddle Enucleated Neuroblastoma Cells Form Neurites When Treated with Dibutyryl Cyclic Amp . . . . . . . . . . . . . . . 295 Tsuneyoshi Kuroiwa Studies on Mitochondrial Structure and Function in \bionamePhysarum Polycephalum . . . . . . . . . . . . . . 299 Marcia Perlman and Jules L. Baum and Gordon I. Kaye Fine Structure and Collagen Synthesis Activity of Monolayer Cultures of Rabbit Corneal Endothelium . . . . . . . . . . 306 Liane Reif-Lehrer Effect of washout of inducing steroid on $ \gamma $-glutamyl transferase activity in the cultured chick embryo retina . . 312 James A. McKanna Permeability Modulating Membrane Coats 317 B. R. Oakley and J. D. Dodge Kinetochores Associated with the Nuclear Envelope in the Mitosis of a Dinoflagellate . . . . . . . . . . . . . 322 Ronald A. Coss Mitosis in Chlamydomonas Reinhardtii Basal Bodies and the Mitotic Apparatus 325 H. L. Atwood and B. Pomeranz Crustacean Motor Neuron Connections Traced by Backfilling for Electron Microscopy . . . . . . . . . . . . . . . 329 K. T. Tokuyasu Spoke Heads in Sperm Tail of \bionameDrosophila Melanogaster . . . . 334 R. A. Waugh and J. R. Sommer Lamellar Junctional Sarcoplasmic Reticulum . . . . . . . . . . . . . . . 337 Tom Elsdale and Jonathan Bard Cellular Interactions in Morphogenesis of Epithelial Mesenchymal Systems . . . 343 Claude Pricam and Fabienne Humbert and Alain Perrelet and Lelio Orci Gap Junctions in Mesangial and Lacis Cells . . . . . . . . . . . . . . . . . 349
Sven Johnsen and Torbjòrn Stokke and Hans Prydz HeLa Cell Plasma Membranes . . . . . . . 357 S. Ito and G. C. Schofield Studies on the Depletion and Accumulation of Microvilli and Changes in the Tubulovesicular Compartment of Mouse Parietal Cells in Relation to Gastric Acid Secretion . . . . . . . . . 364 Paul Tulkens and Henry Beaufay and André Trouet Analytical Fractionation of Homogenates from Cultured Rat Embryo Fibroblasts . . 383 P. R. Harrison and D. Conkie and N. Affara and J. Paul In Situ Localization of Globin Messenger RNA Formation . . . . . . . . . . . . . 402 D. Conkie and N. Affara and P. R. Harrison and J. Paul and K. Jones In Situ Localization of Globin Messenger RNA Formation . . . . . . . . . . . . . 414 David H. Miller and Ira Seth Mellman and Derek T. A. Lamport and Maureen Miller The Chemical Composition of the Cell Wall of Chlamydomonas Gymnogama and the Concept of a Plant Cell Wall Protein . . 420 Maurice Wibo and Brian Poole Protein Degradation in Cultured Cells 430 C. W. Cotman and G. Banker and L. Churchill and D. Taylor Isolation of Postsynaptic Densities from Rat Brain . . . . . . . . . . . . . . . 441 G. Banker and L. Churchill and C. W. Cotman Proteins of the Postsynaptic Density . . 456 Daniel S. Friend and Irene Rudolf Acrosomal Disruption in Sperm . . . . . 466 John C. Saari The Accessibility of Bovine Rhodopsin in Photoreceptor Membranes . . . . . . . . 480 Wayne E. Magee and Charles W. Goff and Jean Schoknecht and M. Diane Smith and K. Cherian The Interaction of Cationic Liposomes Containing Entrapped Horseradish Peroxidase with Cells in Culture . . . . 492 Saul Kit and Wai-Choi Leung and George Jorgensen and David Trkula and Del Rose Dubbs Acquisition of Chick Cytosol Thymidine Kinase Activity by Thymidine Kinase-Deficient Mouse Fibroblast Cells After Fusion with Chick Erythrocytes . . 505 Christine J. Skerrow and A. Gedeon Matoltsy Isolation of Epidermal Desmosomes . . . 515 Christine J. Skerrow and A. Gedeon Matoltsy Chemical Characterization of Isolated Epidermal Desmosomes . . . . . . . . . . 524 Robert E. Hinkley and Alvin G. Telser The Effects of Halothane on Cultured Mouse Neuroblastoma Cells . . . . . . . 531 John G. Wood and Barbara J. McLaughlin and Robert P. Barber The Visualization of Concanavalin a Binding Sites in Purkinje Cell Somata and Dendrites of Rat Cerebellum . . . . 541 Robert H. Warren Microtubular Organization in Elongating Myogenic Cells . . . . . . . . . . . . . 550 John E. Rash and Mark H. Ellisman Studies of Excitable Membranes . . . . . 567 Izhak Nir and Michael O. Hall The Ultrastructure of Lipid-Depleted Rod Photoreceptor Membranes . . . . . . . . 587 S. S. Jahromi and H. L. Atwood Three-Dimensional Ultrastructure of the Crayfish Neuromuscular Apparatus . . . . 599 Lionel F. Jaffe and Richard Nuccitelli An Ultrasensitive Vibrating Probe for Measuring Steady Extracellular Currents 614 S. Matsuura and T. Morimoto and Y. Tashiro and T. Higashinakagawa and M. Muramatsu Ultrastructural and Biochemical Studies on the Precursor Ribosomal Particles Isolated from Rat Liver Nucleoli . . . . 629 Daniel S. Friend and Don W. Fawcett Membrane Differentiations in Freeze-Fractured Mammalian Sperm . . . . 641 V. Mare\vs and B. Schultze and W. Maurer Stability of DNA in Purkinje Cell Nuclei of the Mouse . . . . . . . . . . . . . . 665 H. Dariush Fahimi Effect of Buffer Storage on Fine Structure and Catalase Cytochemistry of Peroxisomes . . . . . . . . . . . . . . 675 Kenjiro Wake Development of Vitamin A-Rich Lipid Droplets in Multivesicular Bodies of Rat Liver Stellate Cells . . . . . . . . . . 683 Mathew P. Daniels and Bernd Hamprecht The Ultrastructure of Neuroblastoma Glioma Somatic Cell Hybrids . . . . . . 691 Nancy K. Weller Visualization of Concanavalin A-Binding Sites with Scanning Electron Microscopy 699 Barbara K. Vonderhaar and Yale J. Topper A Role of the Cell Cycle in Hormone-Dependent Differentiation . . . 707
Audrey M. Glauert The High Voltage Electron Microscope in Biology . . . . . . . . . . . . . . . . 717 Yoichi Tamai and Shigeko Matsukawa Araki and Kimio Katsuta and Mei Satake Molecular Composition of the Submicrosomal Membrane Lipid of Rat Brain . . . . . . . . . . . . . . . . . 749 David P. Beck and R. P. Levine Synthesis of Chloroplast Membrane Polypeptides During Synchronous Growth of Chlamydomonas Reinhardtii . . . . . . 759 Robert H. F. Peterson and Judith A. O'Neil and June L. Biedler Some Biochemical Properties of Chinese Hamster Cells Sensitive and Resistant to Actinomycin D . . . . . . . . . . . . . 773 Alan F. Boyne and Timothy P. Bohan and Terence H. Williams Effects of Calcium-Containing Fixation Solutions on Cholinergic Synaptic Vesicles . . . . . . . . . . . . . . . . 780 Glenda C. Webb and Stephen Roth Cell Contact Dependence of Surface Galactosyltransferase Activity As a Function of the Cell Cycle . . . . . . . 796 Wei-Yeh Wang and Wenan Lee Wang and John E. Boynton and Nicholas W. Gillham Genetic Control of Chlorophyll Biosynthesis in Chlamydomonas . . . . . 806 Karl W. Lanks and Jan M. Dorwin and Bruno Papirmeister Increased Rate of Acetylcholinesterase Synthesis in Differentiating Neuroblastoma Cells . . . . . . . . . . 824 Claude Kedinger and Rene Simard The action of $ \alpha $-amanitin on RNA synthesis in Chinese hamster ovary cells 831 Jon C. Daniel and Robert A. Kosher and James E. Hamos and James W. Lash Influence of External Potassium on the Synthesis and Deposition of Matrix Components by Chondrocytes in Vitro . . 843 Dorothea Zucker-Franklin and George Grusky Ultrastructural Analysis of Hematopoietic Colonies Derived from Human Peripheral Blood . . . . . . . . . 855 Stephen J. O'Brien and Yoshio Shimada The $ \alpha $-glycerophosphate cycle in \bionameDrosophila melanogaster . . . . 864 John P. Caulfield and Marilyn G. Farquhar The Permeability of Glomerular Capillaries to Graded Dextrans . . . . . 883 Richard D. Allen Food Vacuole Membrane Growth with Microtubule-Associated Membrane Transport in Paramecium . . . . . . . . 904 A. L. Kierszenbaum and Laura L. Tres Transcription Sites in Spread Meiotic Prophase Chromosomes from Mouse Spermatocytes . . . . . . . . . . . . . 923 Susan Oleszko and Evangelos N. Moudrianakis The Visualization of the Photosynthetic Coupling Factor in Embedded Spinach Chloroplasts . . . . . . . . . . . . . . 936 Ralph M. Steinman and Jonathan M. Silver and Zanvil A. Cohn Pinocytosis in Fibroblasts . . . . . . . 949 Barbara H. Gibbons and I. R. Gibbons Properties of Flagellar ``Rigor Waves'' Formed by Abrupt Removal of Adenosine Triphosphate from Actively Swimming Sea Urchin Sperm . . . . . . . . . . . . . . 970 Walter L. Davis and David B. P. Goodman and Richard J. Schuster and Howard Rasmussen and James H. Martin Effects of Cytochalasin B on the Response of Toad Urinary Bladder to Vasopressin . . . . . . . . . . . . . . 986 Folkert Bode and Hannelore Pockrandt-Hemstedt and Karl Baumann and Rolf Kinne Analysis of the Pinocytic Process in Rat Kidney . . . . . . . . . . . . . . . . . 998 John Rannestad The Regeneration of Cilia in Partially Deciliated \bionameTetrahymena . . . . . 1009 Arnljot Elgsaeter and Daniel Branton Intramembrane Particle Aggregation in Erythrocyte Ghosts . . . . . . . . . . . 1018 A. Amsterdam and J. D. Jamieson Studies on Dispersed Pancreatic Exocrine Cells . . . . . . . . . . . . . . . . . 1037 A. Amsterdam and J. D. Jamieson Studies on Dispersed Pancreatic Exocrine Cells . . . . . . . . . . . . . . . . . 1057 S. L. Palay and S. Billings-Gagliardi and V. Chan-Palay Neuronal Perikarya with Dispersed, Single Ribosomes in the Visual Cortex of Macaca Mulatta . . . . . . . . . . . . . 1074 Kiyoshi Kishi Electron Microscope Studies on Puromycin-Induced Changes in Nerve Cells of the Medulla Oblongata . . . . . . . . 1091 M. Clutter and T. Brady and V. Walbot and I. Sussex Macromolecular Synthesis During Plant Embryogeny . . . . . . . . . . . . . . . 1097