Table of contents for issues of Journal of Cell Biology

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Volume 148, Number 1, January, 2000
Volume 148, Number 2, January, 2000
Volume 148, Number 3, February, 2000
Volume 148, Number 4, February, 2000
Volume 148, Number 5, March, 2000
Volume 148, Number 6, March, 2000
Volume 149, Number 1, April, 2000
Volume 149, Number 2, April, 2000
Volume 149, Number 3, May, 2000
Volume 149, Number 4, May, 2000
Volume 149, Number 5, May, 2000
Volume 149, Number 6, June, 2000
Volume 149, Number 7, June, 2000
Volume 150, Number 1, July, 2000
Volume 150, Number 2, July, 2000
Volume 150, Number 3, August, 2000
Volume 150, Number 4, August, 2000
Volume 150, Number 5, September, 2000
Volume 150, Number 6, September, 2000
Volume 151, Number 1, October, 2000
Volume 151, Number 2, October, 2000
Volume 151, Number 3, October, 2000
Volume 151, Number 4, November, 2000
Volume 151, Number 5, November, 2000
Volume 151, Number 6, December, 2000
Volume 151, Number 7, December, 2000
Volume 152, Number 1, January, 2001
Volume 152, Number 2, January, 2001
Volume 152, Number 3, February, 2001
Volume 152, Number 4, February, 2001
Volume 152, Number 5, March, 2001
Volume 152, Number 6, March, 2001
Volume 153, Number 1, April, 2001
Volume 153, Number 2, April, 2001
Volume 153, Number 3, April, 2001
Volume 153, Number 4, May, 2001
Volume 153, Number 5, May, 2001
Volume 153, Number 6, June, 2001
Volume 153, Number 7, June, 2001
Volume 154, Number 1, July, 2001
Volume 154, Number 2, July, 2001
Volume 154, Number 3, August, 2001
Volume 154, Number 4, August, 2001
Volume 154, Number 5, September, 2001
Volume 154, Number 6, September, 2001
Volume 155, Number 1, October, 2001
Volume 155, Number 2, October, 2001
Volume 155, Number 3, October, 2001
Volume 155, Number 4, November, 2001
Volume 155, Number 5, November, 2001
Volume 155, Number 6, December, 2001
Volume 155, Number 7, December, 2001
Volume 156, Number 1, January, 2002
Volume 156, Number 2, January, 2002
Volume 156, Number 3, February, 2002
Volume 156, Number 4, February, 2002
Volume 156, Number 5, March, 2002
Volume 156, Number 6, March, 2002
Volume 157, Number 1, April, 2002
Volume 157, Number 2, April, 2002
Volume 157, Number 3, April, 2002
Volume 157, Number 4, May, 2002
Volume 157, Number 5, May, 2002
Volume 157, Number 6, June, 2002
Volume 157, Number 7, June, 2002
Volume 158, Number 1, July, 2002
Volume 158, Number 2, July, 2002
Volume 158, Number 3, August, 2002
Volume 158, Number 4, August, 2002
Volume 158, Number 5, September, 2002
Volume 158, Number 6, September, 2002
Volume 158, Number 7, September, 2002
Volume 159, Number 1, October, 2002
Volume 159, Number 2, October, 2002
Volume 159, Number 3, November, 2002
Volume 159, Number 4, November, 2002
Volume 159, Number 5, December, 2002
Volume 159, Number 6, December, 2002
Volume 160, Number 1, January, 2003
Volume 160, Number 2, January, 2003
Volume 160, Number 3, February, 2003
Volume 160, Number 4, February, 2003
Volume 160, Number 5, March, 2003
Volume 160, Number 6, March, 2003
Volume 160, Number 7, March, 2003
Volume 161, Number 1, April, 2003
Volume 161, Number 2, April, 2003
Volume 161, Number 3, May, 2003
Volume 161, Number 4, May, 2003
Volume 161, Number 5, June, 2003
Volume 161, Number 6, June, 2003
Volume 162, Number 1, July, 2003
Volume 162, Number 2, July, 2003
Volume 162, Number 3, August, 2003
Volume 162, Number 4, August, 2003
Volume 162, Number 5, September, 2003
Volume 162, Number 6, September, 2003
Volume 162, Number 7, September, 2003
Volume 163, Number 1, October, 2003
Volume 163, Number 2, October, 2003
Volume 163, Number 3, November, 2003
Volume 163, Number 4, November, 2003
Volume 163, Number 5, December, 2003
Volume 163, Number 6, December, 2003
Volume 164, Number 1, January, 2004
Volume 164, Number 2, January, 2004
Volume 164, Number 3, February, 2004
Volume 164, Number 4, February, 2004
Volume 164, Number 5, March, 2004
Volume 164, Number 6, March, 2004
Volume 164, Number 7, March, 2004
Volume 165, Number 1, April, 2004
Volume 165, Number 2, April, 2004
Volume 165, Number 3, May, 2004
Volume 165, Number 4, May, 2004
Volume 165, Number 5, June, 2004
Volume 165, Number 6, June, 2004
Volume 166, Number 1, July, 2004
Volume 166, Number 2, July, 2004
Volume 166, Number 3, August, 2004
Volume 166, Number 4, August, 2004
Volume 166, Number 5, August, 2004
Volume 166, Number 6, September, 2004
Volume 166, Number 7, September, 2004
Volume 167, Number 1, October, 2004
Volume 167, Number 2, October, 2004
Volume 167, Number 3, November, 2004
Volume 167, Number 4, November, 2004
Volume 167, Number 5, December, 2004
Volume 167, Number 6, December, 2004
Volume 220, Number 5, May 3, 2021


Journal of Cell Biology
Volume 148, Number 1, January, 2000

               William A. Wells   In Brief . . . . . . . . . . . . . . . . ??
                    Ira Mellman   A New Year's Letter from The Editor  . . ??
          David J. DeRosier and   
                Lewis G. Tilney   F-Actin Bundles Are Derivatives of
                                  Microvilli . . . . . . . . . . . . . . . 1
         Michael P. Czubryt and   
       J. Alejandro Austria and   
                Grant N. Pierce   Hydrogen Peroxide Inhibition of Nuclear
                                  Protein Import Is Mediated by the
                                  Mitogen--Activated Protein Kinase, Erk2  7
           Thomas Machleidt and   
                Wei-Ping Li and   
              Pingsheng Liu and   
         Richard G. W. Anderson   Multiple Domains in Caveolin-1 Control
                                  Its Intracellular Traffic  . . . . . . . 17
      Vladimir I. Titorenko and   
                 Honey Chan and   
         Richard A. Rachubinski   Fusion of Small Peroxisomal Vesicles in
                                  Vitro Reconstructs an Early Step in the
                                  in Vivo Multistep Peroxisome Assembly
                                  Pathway of Yarrowia lipolytica . . . . . 29
        Roman S. Polishchuk and   
        Elena V. Polishchuk and   
        Pierfrancesco Marra and   
            Saverio Alberti and   
           Roberto Buccione and   
              Alberto Luini and   
           Alexander A. Mironov   Correlative Light--Electron Microscopy
                                  Reveals the Tubular--Saccular
                                  Ultrastructure of Carriers Operating
                                  between Golgi Apparatus and Plasma
                                  Membrane . . . . . . . . . . . . . . . . 45
            Kevin J. Harvey and   
              Dunja Lukovic and   
                 David S. Ucker   Caspase-Dependent Cdk Activity Is a
                                  Requisite Effector of Apoptotic Death
                                  Events . . . . . . . . . . . . . . . . . 59
          Monique A. Lorson and   
          H. Robert Horvitz and   
          Sander van den Heuvel   LIN-5 Is a Novel Component of the
                                  Spindle Apparatus Required for
                                  Chromosome Segregation and Cleavage
                                  Plane Specification in
                                  \bionameCaenorhabditis elegans . . . . . 73
            Lewis G. Tilney and   
       Patricia S. Connelly and   
           Kelly A. Vranich and   
            Michael K. Shaw and   
               Gregory M. Guild   Regulation of Actin Filament
                                  Cross-linking and Bundle Shape in
                                  \bionameDrosophila Bristles  . . . . . . 87
              Satoko Hakeda and   
               Sachiko Endo and   
                    Kaoru Saigo   Requirements of Kettin, a Giant Muscle
                                  Protein Highly Conserved in Overall
                                  Structure in Evolution, for Normal
                                  Muscle Function, Viability, and Flight
                                  Activity of \bionameDrosophila . . . . . 101
          Terri G. Thompson and   
                Yiu-Mo Chan and   
             Andrew A. Hack and   
            Melissa Brosius and   
             Michael Rajala and   
           Hart G. W. Lidov and   
       Elizabeth M. McNally and   
              Simon Watkins and   
                Louis M. Kunkel   Filamin 2 (FLN2): a Muscle-specific
                                  Sarcoglycan Interacting Protein  . . . . 115
             Drazen Raucher and   
              Michael P. Sheetz   Cell Spreading and Lamellipodial
                                  Extension Rate Is Regulated by Membrane
                                  Tension  . . . . . . . . . . . . . . . . 127
       Michael A. McCloskey and   
                      Lei Zhang   Potentiation of Fc$ \epsilon $ Receptor
                                  I-activated Ca$^{2+}$ Current (I$_{\rm
                                  CRAC}$) by Cholera Toxin: Possible
                                  Mediation by ADP Ribosylation Factor . . 137
          Amanda M. Tiffany and   
          Louis N. Manganas and   
                Eunjoon Kim and   
              Yi-Ping Hsueh and   
               Morgan Sheng and   
               James S. Trimmer   PSD-95 and SAP97 Exhibit Distinct
                                  Mechanisms for Regulating K$^+$ Channel
                                  Surface Expression and Clustering  . . . 147
        Alaa E. El-Husseini and   
            Sarah E. Craven and   
         Dane M. Chetkovich and   
        Bonnie L. Firestein and   
               Eric Schnell and   
                 Chiye Aoki and   
                 David S. Bredt   Dual Palmitoylation of Psd-95 Mediates
                                  Its Vesiculotubular Sorting,
                                  Postsynaptic Targeting, and Ion Channel
                                  Clustering . . . . . . . . . . . . . . . 159
               Andreas Eger and   
         Andreas Stockinger and   
        Birgit Schaffhauser and   
               Hartmut Beug and   
                 Roland Foisner   Epithelial Mesenchymal Transition by
                                  c-Fos Estrogen Receptor Activation
                                  Involves Nuclear Translocation of $
                                  \beta $-Catenin and Upregulation of $
                                  \beta $-Catenin/Lymphoid Enhancer
                                  Binding Factor-1 Transcriptional
                                  Activity . . . . . . . . . . . . . . . . 173
          Molly A. Thoreson and   
      Panos Z. Anastasiadis and   
           Juliet M. Daniel and   
     Reneé C. Ireton and   
       Margaret J. Wheelock and   
           Keith R. Johnson and   
       Diana K. Hummingbird and   
             Albert B. Reynolds   Selective Uncoupling of P120$^{\rm ctn}$
                                  from E--Cadherin Disrupts Strong
                                  Adhesion . . . . . . . . . . . . . . . . 189
        Jennifer R. Allport and   
          William A. Muller and   
          Francis W. Luscinskas   Monocytes Induce Reversible Focal
                                  Changes in Vascular Endothelial Cadherin
                                  Complex during Transendothelial
                                  Migration under Flow . . . . . . . . . . 203

Journal of Cell Biology
Volume 148, Number 2, January, 2000

              Laura M. Machesky   The Tails of Two Myosins . . . . . . . . 219
                 Patrik Ernfors   Nuclear Factor-$ \kappa $ b to the
                                  Rescue of Cytokine--Induced Neuronal
                                  Survival . . . . . . . . . . . . . . . . 223
           Arthur D. Lander and   
               Scott B. Selleck   The Elusive Functions of Proteoglycans   227
     Enrique Martinez-Perez and   
              Peter J. Shaw and   
                   Graham Moore   Polyploidy Induces Centromere
                                  Association  . . . . . . . . . . . . . . 233
        Josée Dostie and   
          Flavio Lejbkowicz and   
                Nahum Sonenberg   Nuclear Eukaryotic Initiation Factor 4e
                                  (Eif4e) Colocalizes with Splicing
                                  Factors in Speckles  . . . . . . . . . . 239
                   Bin Yang and   
          Martin Steegmaier and   
           Lino C. Gonzalez and   
            Richard H. Scheller   Nsec1 Binds a Closed Conformation of
                                  Syntaxin1a . . . . . . . . . . . . . . . 247
       Kathleen L. O'Connor and   
             Bao-Kim Nguyen and   
             Arthur M. Mercurio   Rhoa Function in Lamellae Formation and
                                  Migration Is Regulated by the $ \alpha
                                  $6$ \beta $4 Integrin and Camp
                                  Metabolism . . . . . . . . . . . . . . . 253
            Valentina Sirri and   
             Pascal Roussel and   
     Dani\`ele Hernandez-Verdun   In Vivo Release of Mitotic Silencing of
                                  Ribosomal Gene Transcription Does Not
                                  Give Rise to Precursor Ribosomal RNA
                                  Processing . . . . . . . . . . . . . . . 259
          Francesc Miralles and   
Lars-Göran Öfverstedt and   
              Nafiseh Sabri and   
           Youssef Aissouni and   
                Ulf Hellman and   
               Ulf Skoglund and   
                      Neus Visa   Electron Tomography Reveals
                                  Posttranscriptional Binding of
                                  Pre--Mrnps to Specific Fibers in the
                                  Nucleoplasm  . . . . . . . . . . . . . . 271
François-Michel Boisvert and   
         Michael J. Hendzel and   
          David P. Bazett-Jones   Promyelocytic Leukemia (Pml) Nuclear
                                  Bodies Are Protein Structures That Do
                                  Not Accumulate RNA . . . . . . . . . . . 283
              Martin Hetzer and   
                 Iain W. Mattaj   An ATP--Dependent, Ran--Independent
                                  Mechanism for Nuclear Import of the U1a
                                  and U2b'' Spliceosome Proteins . . . . . 293
         Florencia Schapiro and   
           Jason Sparkowski and   
                Alex Adduci and   
          Frank Suprynowicz and   
           Richard Schlegel and   
               Sergio Grinstein   Golgi Alkalinization by the
                                  Papillomavirus E5 Oncoprotein  . . . . . 305
                Julia Avery and   
            Darren J. Ellis and   
              Thorsten Lang and   
            Phillip Holroyd and   
             Dietmar Riedel and   
        Robert M. Henderson and   
       J. Michael Edwardson and   
                  Reinhard Jahn   A Cell--Free System for Regulated
                                  Exocytosis in Pc12 Cells . . . . . . . . 317
            Gayle Middleton and   
            Makoto Hamanoue and   
            Yasushi Enokido and   
                 Sean Wyatt and   
              Diane Pennica and   
              Ellis Jaffray and   
              Ronald T. Hay and   
                 Alun M. Davies   Cytokine-Induced Nuclear Factor Kappa B
                                  Activation Promotes the Survival of
                                  Developing Neurons . . . . . . . . . . . 325
          Tsuyoshi Miyazaki and   
            Hideki Katagiri and   
               Yumi Kanegae and   
         Hiroshi Takayanagi and   
            Yasuhiro Sawada and   
          Aiichiro Yamamoto and   
            Mattew P. Pando and   
           Tomoichiro Asano and   
             Inder M. Verma and   
                 Hiromi Oda and   
              Kozo Nakamura and   
                   Sakae Tanaka   Reciprocal Role of ERK and Nf-$ \kappa $
                                  b Pathways in Survival and Activation of
                                  Osteoclasts  . . . . . . . . . . . . . . 333
               Connie Myers and   
           Aubri Charboneau and   
                 Nancy Boudreau   Homeobox B3 Promotes Capillary
                                  Morphogenesis and Angiogenesis . . . . . 343
          Marie Evangelista and   
              Bert M. Klebl and   
             Amy H. Y. Tong and   
            Bradley A. Webb and   
               Thomas Leeuw and   
           Ekkehard Leberer and   
           Malcolm Whiteway and   
            David Y. Thomas and   
                  Charles Boone   A Role for Myosin-I in Actin Assembly
                                  through Interactions with Vrp1p, Bee1p,
                                  and the Arp2/3 Complex . . . . . . . . . 353
              Terry Lechler and   
            Anna Shevchenko and   
          Andrej Shevchenko and   
                        Rong Li   Direct Involvement of Yeast Type I
                                  Myosins in Cdc42-Dependent Actin
                                  Polymerization . . . . . . . . . . . . . 363
                 Wanyuan Ao and   
                   Dave Pilgrim   \bionameCaenorhabditis elegans Unc-45 Is
                                  a Component of Muscle Thick Filaments
                                  and Colocalizes with Myosin Heavy Chain
                                  B, but Not Myosin Heavy Chain A  . . . . 375
      Kathryn S. R. Spencer and   
          Diana Graus-Porta and   
                   Jie Leng and   
             Nancy E. Hynes and   
              Richard L. Klemke   ErbB2 Is Necessary for Induction of
                                  Carcinoma Cell Invasion by Erbb Family
                                  Receptor Tyrosine Kinases  . . . . . . . 385

Journal of Cell Biology
Volume 148, Number 3, February, 2000

              Barry M. Gumbiner   Regulation of Cadherin Adhesive Activity 399
        Sandrine Middendorp and   
      Thomas Küntziger and   
               Yann Abraham and   
               Simon Holmes and   
              Nicole Bordes and   
           Michel Paintrand and   
              Anne Paoletti and   
                 Michel Bornens   A Role for Centrin 3 in Centrosome
                                  Reproduction . . . . . . . . . . . . . . 405
             Hengjiang Dong and   
             G. Shirleen Roeder   Organization of the Yeast Zip1 Protein
                                  within the Central Region of the
                                  Synaptonemal Complex . . . . . . . . . . 417
           James E. Wilhelm and   
         Jennifer Mansfield and   
            Nora Hom-Booher and   
             Shengxian Wang and   
         Christoph W. Turck and   
            Tulle Hazelrigg and   
                 Ronald D. Vale   Isolation of a Ribonucleoprotein Complex
                                  Involved in mRNA Localization in
                                  \bionameDrosophila Oocytes . . . . . . . 427
               Marisa Segal and   
           Duncan J. Clarke and   
                Paul Maddox and   
               E. D. Salmon and   
                Kerry Bloom and   
                 Steven I. Reed   Coordinated Spindle Assembly and
                                  Orientation Requires Clb5p--Dependent
                                  Kinase in Budding Yeast  . . . . . . . . 441
           Kiminori Toyooka and   
            Takashi Okamoto and   
               Takao Minamikawa   Mass Transport of Proform of a
                                  Kdel--Tailed Cysteine Proteinase
                                  (Sh--EP) to Protein Storage Vacuoles by
                                  Endoplasmic Reticulum--Derived Vesicle
                                  Is Involved in Protein Mobilization in
                                  Germinating Seeds  . . . . . . . . . . . 453
               Takeshi Noda and   
                   John Kim and   
             Wei-Pang Huang and   
                Misuzu Baba and   
           Chikara Tokunaga and   
           Yoshinori Ohsumi and   
             Daniel J. Klionsky   Apg9p\slash Cvt7p Is an Integral
                                  Membrane Protein Required for Transport
                                  Vesicle Formation in the Cvt and
                                  Autophagy Pathways . . . . . . . . . . . 465
      Elizabeth Hong-Geller and   
             Richard A. Cerione   Cdc42 and Rac Stimulate Exocytosis of
                                  Secretory Granules by Activating the
                                  Ip$_3$ /Calcium Pathway in Rbl-2h3 Mast
                                  Cells  . . . . . . . . . . . . . . . . . 481
         Jennifer R. Henkel and   
          Gregory A. Gibson and   
             Paul A. Poland and   
              Mark A. Ellis and   
          Rebecca P. Hughey and   
                   Ora A. Weisz   Influenza M2 Proton Channel Activity
                                  Selectively Inhibits Trans-Golgi Network
                                  Release of Apical Membrane and Secreted
                                  Proteins in Polarized Madin--Darby
                                  Canine Kidney Cells  . . . . . . . . . . 495
        Yuko Mimori-Kiyosue and   
            Nobuyuki Shiina and   
              Shoichiro Tsukita   Adenomatous Polyposis Coli (APC) Protein
                                  Moves along Microtubules and
                                  Concentrates at Their Growing Ends in
                                  Epithelial Cells . . . . . . . . . . . . 505
               Jack Taunton and   
           Brian A. Rowning and   
       Margaret L. Coughlin and   
                 Michael Wu and   
            Randall T. Moon and   
       Timothy J. Mitchison and   
            Carolyn A. Larabell   Actin-Dependent Propulsion of Endosomes
                                  and Lysosomes by Recruitment of N-Wasp   519
             Amanda Y. Chan and   
              Maryse Bailly and   
           Noureddine Zebda and   
          Jeffrey E. Segall and   
              John S. Condeelis   Role of Cofilin in Epidermal Growth
                                  Factor--Stimulated Actin Polymerization
                                  and Lamellipod Protrusion  . . . . . . . 531
            Marc J. Servant and   
          Philippe Coulombe and   
           Benjamin Turgeon and   
                Sylvain Meloche   Differential Regulation of P27$^{\rm
                                  Kip1}$ Expression by Mitogenic and
                                  Hypertrophic Factors . . . . . . . . . . 543
            Hirotaka Kazama and   
                  Shin Yonehara   Oncogenic K--Ras and Basic Fibroblast
                                  Growth Factor Prevent FAS-Mediated
                                  Apoptosis in Fibroblasts through
                                  Activation of Mitogen-Activated Protein
                                  Kinase . . . . . . . . . . . . . . . . . 557
             Joerg Huelsken and   
               Regina Vogel and   
           Volker Brinkmann and   
            Bettina Erdmann and   
          Carmen Birchmeier and   
              Walter Birchmeier   Requirement for $ \beta $-Catenin in
                                  Anterior--Posterior Axis Formation in
                                  Mice . . . . . . . . . . . . . . . . . . 567
              Wei-Song Shan and   
            Hidekazu Tanaka and   
           Greg R. Phillips and   
              Kirsten Arndt and   
               Mika Yoshida and   
            David R. Colman and   
               Lawrence Shapiro   Functional Cis--Heterodimers of N- and
                                  R--Cadherins . . . . . . . . . . . . . . 579
                    Wen Shi and   
                Huizhou Fan and   
               Lillian Shum and   
                    Rik Derynck   The Tetraspanin Cd9 Associates with
                                  Transmembrane TGF-$ \alpha $ and
                                  Regulates TGF-$ \alpha $-Induced Egf
                                  Receptor Activation and Cell
                                  Proliferation  . . . . . . . . . . . . . 591
                  Adam Zweifach   Target-Cell Contact Activates a Highly
                                  Selective Capacitative Calcium Entry
                                  Pathway in Cytotoxic T Lymphocytes . . . 603
          Naohiko Koshikawa and   
        Gianluigi Giannelli and   
           Vincenzo Cirulli and   
             Kaoru Miyazaki and   
                  Vito Quaranta   Role of Cell Surface Metalloprotease
                                  Mt1-Mmp in Epithelial Cell Migration
                                  over Laminin-5 . . . . . . . . . . . . . 615

Journal of Cell Biology
Volume 148, Number 4, February, 2000

                    Po Chen and   
                 John M. Abrams   Drosophila Apoptosis and Bcl-2 Genes . . 625
             Wolfgang Mayer and   
                Avril Smith and   
            Reinald Fundele and   
                    Thomas Haaf   Spatial Separation of Parental Genomes
                                  in Preimplantation Mouse Embryos . . . . 629
            Michael P. Rout and   
          John D. Aitchison and   
     Adisetyantari Suprapto and   
             Kelly Hjertaas and   
              Yingming Zhao and   
                 Brian T. Chait   The Yeast Nuclear Pore Complex . . . . . 635
           Tsuyoshi Okagaki and   
              Akio Nakamura and   
            Tomohiko Suzuki and   
              Kazuhiro Ohmi and   
                Kazuhiro Kohama   Assembly of Smooth Muscle Myosin by the
                                  38k Protein, a Homologue of a Subunit of
                                  Pre-mRNA Splicing Factor-2 . . . . . . . 653
        Meenakshi Chellaiah and   
                 Neil Kizer and   
              Matthew Silva and   
             Ulises Alvarez and   
          David Kwiatkowski and   
                Keith A. Hruska   Gelsolin Deficiency Blocks Podosome
                                  Assembly and Produces Increased Bone
                                  Mass and Strength  . . . . . . . . . . . 665
           Andrea D. Weston and   
                Vicki Rosen and   
Roshantha A. S. Chandraratna and   
           T. Michael Underhill   Regulation of Skeletal Progenitor
                                  Differentiation by the Bmp and Retinoid
                                  Signaling Pathways . . . . . . . . . . . 679
               Gist H. Farr and   
           Denise M. Ferkey and   
               Cynthia Yost and   
            Sarah B. Pierce and   
              Carole Weaver and   
                 David Kimelman   Interaction among Gsk-3, Gbp, Axin, and
                                  APC in \bionameXenopus Axis
                                  Specification  . . . . . . . . . . . . . 691
            Paul A. Colussi and   
            Leonie M. Quinn and   
          David C. S. Huang and   
            Michelle Coombe and   
             Stuart H. Read and   
          Helena Richardson and   
                   Sharad Kumar   Debcl, a Proapoptotic Bcl-2 Homologue,
                                  Is a Component of the \bionameDrosophila
                                  melanogaster Cell Death Machinery  . . . 703
           Rainer Pepperkok and   
      Agnes Hotz-Wagenblatt and   
         Norbert König and   
              Andreas Girod and   
            Dirk Bossemeyer and   
                  Volker Kinzel   Intracellular Distribution of Mammalian
                                  Protein Kinase a Catalytic Subunit
                                  Altered by Conserved Asn2 Deamidation    715
               Paul Verkade and   
              Thomas Harder and   
               Frank Lafont and   
                     Kai Simons   Induction of Caveolae in the Apical
                                  Plasma Membrane of Madin--Darby Canine
                                  Kidney Cells . . . . . . . . . . . . . . 727
           Konark Mukherjee and   
          Shadab A. Siddiqi and   
              Shehla Hashim and   
                 Manoj Raje and   
             Sandip K. Basu and   
          Amitabha Mukhopadhyay   Live Salmonella Recruits N
                                  --Ethylmaleimide--Sensitive Fusion
                                  Protein on Phagosomal Membrane and
                                  Promotes Fusion with Early Endosome  . . 741
            Robert M. Smith and   
             Boris Baibakov and   
         Yoshihide Ikebuchi and   
          Benjamin H. White and   
           Nevin A. Lambert and   
       Leonard K. Kaczmarek and   
                Steven S. Vogel   Exocytotic Insertion of Calcium Channels
                                  Constrains Compensatory Endocytosis to
                                  Sites of Exocytosis  . . . . . . . . . . 755
             Lisa A. Dunbar and   
               Paul Aronson and   
              Michael J. Caplan   A Transmembrane Segment Determines the
                                  Steady--State Localization of an
                                  Ion--Transporting Adenosine
                                  Triphosphatase . . . . . . . . . . . . . 769
            Rachel B. Hazan and   
           Greg R. Phillips and   
              Rui Fang Qiao and   
               Larry Norton and   
             Stuart A. Aaronson   Exogenous Expression of N--Cadherin in
                                  Breast Cancer Cells Induces Cell
                                  Migration, Invasion, and Metastasis  . . 779
                   Danxi Li and   
               Randall J. Mrsny   Oncogenic Raf-1 Disrupts Epithelial
                                  Tight Junctions via Downregulation of
                                  Occludin . . . . . . . . . . . . . . . . 791
               Mark A. Bowe and   
            Duane B. Mendis and   
               Justin R. Fallon   The Small Leucine--Rich Repeat
                                  Proteoglycan Biglycan Binds to $ \alpha
                                  $-Dystroglycan and Is Upregulated in
                                  Dystrophic Muscle  . . . . . . . . . . . 801
      Marilyn L. Fitzgerald and   
                 Zihua Wang and   
             Pyong Woo Park and   
             Gillian Murphy and   
               Merton Bernfield   Shedding of Syndecan-1 and -4
                                  Ectodomains Is Regulated by Multiple
                                  Signaling Pathways and Mediated by a
                                  Timp-3--Sensitive Metalloproteinase  . . 811
           Sergey S. Akimov and   
              Dmitry Krylov and   
       Laurie F. Fleischman and   
               Alexey M. Belkin   Tissue Transglutaminase Is an
                                  Integrin--Binding Adhesion Coreceptor
                                  for Fibronectin  . . . . . . . . . . . . 825

Journal of Cell Biology
Volume 148, Number 5, March, 2000

                     Mark Noble   Precursor Cell Transitions in
                                  Oligodendrocyte Development  . . . . . . 839
       Sergei N. Prokopenko and   
               Robert Saint and   
                 Hugo J. Bellen   Untying the Gordian Knot of Cytokinesis  843
              Makoto Adachi and   
              Makoto Fukuda and   
                 Eisuke Nishida   Nuclear Export of Map Kinase (ERK)
                                  Involves a Map Kinase Kinase
                                  (Mek--Dependent) Active Transport
                                  Mechanism  . . . . . . . . . . . . . . . 849
               Paolo Pinton and   
             Davide Ferrari and   
     Paulo Magalhães and   
      Klaus Schulze-Osthoff and   
      Francesco Di Virgilio and   
              Tullio Pozzan and   
                Rosario Rizzuto   Reduced Loading of Intracellular
                                  Ca$^{2+}$ Stores and Downregulation of
                                  Capacitative Ca$^{2+}$ Influx in
                                  Bcl-2--Overexpressing Cells  . . . . . . 857
                    Yu Chen and   
               Sanford M. Simon   In Situ Biochemical Demonstration That
                                  P--Glycoprotein Is a Drug Efflux Pump
                                  with Broad Specificity . . . . . . . . . 863
          Kevin G. Hardwick and   
        Raymond C. Johnston and   
              Dana L. Smith and   
               Andrew W. Murray   MAD3 Encodes a Novel Component of the
                                  Spindle Checkpoint Which Interacts with
                                  Bub3p, Cdc20p, and Mad2p . . . . . . . . 871
                Lars Dreier and   
                Tom A. Rapoport   In Vitro Formation of the Endoplasmic
                                  Reticulum Occurs Independently of
                                  Microtubules by a Controlled Fusion
                                  Reaction . . . . . . . . . . . . . . . . 883
        Emanuela Pedrazzini and   
            Antonello Villa and   
              Renato Longhi and   
      Alessandra Bulbarelli and   
                   Nica Borgese   Mechanism of Residence of Cytochrome
                                  B(5), a Tail--Anchored Protein, in the
                                  Endoplasmic Reticulum  . . . . . . . . . 899
          Stephen R. Cronin and   
                Afif Khoury and   
              Dana K. Ferry and   
            Randolph Y. Hampton   Regulation of HMG--Coa Reductase
                                  Degradation Requires the P-Type ATPase
                                  Cod1p/Spf1p  . . . . . . . . . . . . . . 915
        Manuel Muñiz and   
             Claude Nuoffer and   
           Hans-Peter Hauri and   
                 Howard Riezman   The Emp24 Complex Recruits a Specific
                                  Cargo Molecule into Endoplasmic
                                  Reticulum--Derived Vesicles  . . . . . . 925
    Katherine A. Sacksteder and   
             Jacob M. Jones and   
             Sarah T. South and   
                Xiaoling Li and   
                  Yifei Liu and   
               Stephen J. Gould   Pex19 Binds Multiple Peroxisomal
                                  Membrane Proteins, Is Predominantly
                                  Cytoplasmic, and Is Required for
                                  Peroxisome Membrane Synthesis  . . . . . 931
            Steven P. Gross and   
           Michael A. Welte and   
            Steven M. Block and   
              Eric F. Wieschaus   Dynein-Mediated Cargo Transport in Vivo  945
       Valérie Petit and   
             Brigitte Boyer and   
             Delphine Lentz and   
      Christopher E. Turner and   
           Jean Paul Thiery and   
           Ana M. Vallés   Phosphorylation of Tyrosine Residues 31
                                  and 118 on Paxillin Regulates Cell
                                  Migration through an Association with
                                  Crk in Nbt--II Cells . . . . . . . . . . 957
               Dean G. Tang and   
       Yasuhito M. Tokumoto and   
                 Martin C. Raff   Long-Term Culture of Purified Postnatal
                                  Oligodendrocyte Precursor Cells  . . . . 971
                   Q. L. Lu and   
               G. E. Morris and   
               S. D. Wilton and   
                      T. Ly and   
           O. V. Artem'yeva and   
                  P. Strong and   
                T. A. Partridge   Massive Idiosyncratic Exon Skipping
                                  Corrects the Nonsense Mutation in
                                  Dystrophic Mouse Muscle and Produces
                                  Functional Revertant Fibers by Clonal
                                  Expansion  . . . . . . . . . . . . . . . 985
                  A. Pralle and   
                  P. Keller and   
               E.-L. Florin and   
                  K. Simons and   
           J. K. H. Hörber   Sphingolipid--Cholesterol Rafts Diffuse
                                  as Small Entities in the Plasma Membrane
                                  of Mammalian Cells . . . . . . . . . . . 997
                     X. Yin and   
                 G. J. Kidd and   
                 L. Wrabetz and   
               M. L. Feltri and   
                 A. Messing and   
                    B. D. Trapp   Schwann Cell Myelination Requires Timely
                                  and Precise Targeting of P$_0$ Protein   1009
           Lawrence Wrabetz and   
         Maria Laura Feltri and   
           Angelo Quattrini and   
          Daniele Imperiale and   
          Stefano Previtali and   
         Maurizio D'Antonio and   
             Rudolf Martini and   
                Xinghua Yin and   
             Bruce D. Trapp and   
                   Lei Zhou and   
             Shing-Yan Chiu and   
                  Albee Messing   P$_0$ Glycoprotein Overexpression Causes
                                  Congenital Hypomyelination of Peripheral
                                  Nerves . . . . . . . . . . . . . . . . . 1021
        Alistair N. Garratt and   
        Octavian Voiculescu and   
              Piotr Topilko and   
            Patrick Charnay and   
              Carmen Birchmeier   A Dual Role of erbB2 in Myelination and
                                  in Expansion of the Schwann Cell
                                  Precursor Pool . . . . . . . . . . . . . 1035
            Britta Qualmann and   
                 Regis B. Kelly   Syndapin Isoforms Participate in
                                  Receptor-Mediated Endocytosis and Actin
                                  Organization . . . . . . . . . . . . . . 1047
         Arjan Pieter Quist and   
            Seung Keun Rhee and   
                    Hai Lin and   
                 Ratneshwar Lal   Physiological Role of Gap--Junctional
                                  Hemichannels . . . . . . . . . . . . . . 1063
              Roumen Pankov and   
             Edna Cukierman and   
              Ben-Zion Katz and   
            Kazue Matsumoto and   
               Diane C. Lin and   
                   Shin Lin and   
              Cornelia Hahn and   
              Kenneth M. Yamada   Integrin Dynamics and Matrix Assembly    1075

Journal of Cell Biology
Volume 148, Number 6, March, 2000

             Thoru Pederson and   
                 Joan C. Politz   The Nucleolus and the Four
                                  Ribonucleoproteins of Translation  . . . 1091
               N. Ronald Morris   Nuclear Migration  . . . . . . . . . . . 1097
             Harold P. Erickson   Dynamin and Ftsz . . . . . . . . . . . . 1103
           Roberto Giordano and   
          Anna Rosa Magnano and   
         Germana Zaccagnini and   
           Carmine Pittoggi and   
             Nicola Moscufo and   
          Rodolfo Lorenzini and   
              Corrado Spadafora   Reverse Transcriptase Activity in Mature
                                  Spermatozoa of Mouse . . . . . . . . . . 1107
              Aljoscha Nern and   
             Robert A. Arkowitz   Nucleocytoplasmic Shuttling of the
                                  Cdc42p Exchange Factor Cdc24p  . . . . . 1115
        E. Sergio Trombetta and   
                   Ari Helenius   Conformational Requirements for
                                  Glycoprotein Reglucosylation in the
                                  Endoplasmic Reticulum  . . . . . . . . . 1123
              Chantal Guiet and   
                  Pasquale Vito   Caspase Recruitment Domain
                                  (Card--Dependent) Cytoplasmic Filaments
                                  Mediate Bcl10-Induced Nf-$ \kappa $ b
                                  Activation . . . . . . . . . . . . . . . 1131
      Iñigo Martinez and   
     Sabyasachi Chakrabarti and   
             Turid Hellevik and   
          Jennifer Morehead and   
            Kimberly Fowler and   
               Norma W. Andrews   Synaptotagmin VII Regulates Ca$^{2+}$
                                  -Dependent Exocytosis of Lysosomes in
                                  Fibroblasts  . . . . . . . . . . . . . . 1141
          Kris A. Reedquist and   
                  Ewan Ross and   
            Elianne A. Koop and   
         Rob M. F. Wolthuis and   
     Fried J. T. Zwartkruis and   
           Yvette van Kooyk and   
                Mike Salmon and   
     Christopher D. Buckley and   
                Johannes L. Bos   The Small Gtpase, Rap1, Mediates
                                  Cd31-Induced Integrin Adhesion . . . . . 1151
        Snezhana Oliferenko and   
             Irina Kaverina and   
            J. Victor Small and   
                 Lukas A. Huber   Hyaluronic Acid (Ha) Binding to Cd44
                                  Activates Rac1 and Induces Lamellipodia
                                  Outgrowth  . . . . . . . . . . . . . . . 1159
                  Sirpa Aho and   
            Monique Buisson and   
              Tiina Pajunen and   
              Young W. Ryoo and   
  Jean-François Giot and   
              Henry Gruffat and   
             Alain Sergeant and   
                    Jouni Uitto   Ubinuclein, a Novel Nuclear Protein
                                  Interacting with Cellular and Viral
                                  Transcription Factors  . . . . . . . . . 1165
           Bernard Charroux and   
           Livio Pellizzoni and   
        Robert A. Perkinson and   
              Jeongsik Yong and   
          Andrej Shevchenko and   
              Matthias Mann and   
                Gideon Dreyfuss   Gemin4 . . . . . . . . . . . . . . . . . 1177
         R. Montgomery Gill and   
                  Paul A. Hamel   Subcellular Compartmentalization of E2f
                                  Family Members Is Required for
                                  Maintenance of the Postmitotic State in
                                  Terminally Differentiated Muscle . . . . 1187
              Anton Schmitz and   
              Helga Herrgen and   
         Alexandra Winkeler and   
                  Volker Herzog   Cholera Toxin Is Exported from
                                  Microsomes by the Sec61p Complex . . . . 1203
                Karen Sohrt and   
               Jürgen Soll   Toc64, a New Component of the Protein
                                  Translocon of Chloroplasts . . . . . . . 1213
               Albert Price and   
            William Wickner and   
            Christian Ungermann   Proteins Needed for Vesicle Budding from
                                  the Golgi Complex Are Also Required for
                                  the Docking Step of Homotypic Vacuole
                                  Fusion . . . . . . . . . . . . . . . . . 1223
               Albert Price and   
               Darren Seals and   
            William Wickner and   
            Christian Ungermann   The Docking Stage of Yeast Vacuole
                                  Fusion Requires the Transfer of Proteins
                                  from a Cis-Snare Complex to a Rab/Ypt
                                  Protein  . . . . . . . . . . . . . . . . 1231
          Marion MacFarlane and   
             Wendy Merrison and   
             David Dinsdale and   
                Gerald M. Cohen   Active Caspases and Cleaved Cytokeratins
                                  Are Sequestered into Cytoplasmic
                                  Inclusions in Trail--Induced Apoptosis   1239
                 Sen Takeda and   
            Hiroto Yamazaki and   
              Dae-Hyun Seog and   
           Yoshimitsu Kanai and   
               Sumio Terada and   
              Nobutaka Hirokawa   Kinesin Superfamily Protein 3 (Kif3)
                                  Motor Transports Fodrin--Associating
                                  Vesicles Important for Neurite Building  1255
                K. A. DeFea and   
                J. Zalevsky and   
                M. S. Thoma and   
             O. Déry and   
              R. D. Mullins and   
                  N. W. Bunnett   $ \beta $-Arrestin--Dependent
                                  Endocytosis of Proteinase--Activated
                                  Receptor 2 Is Required for Intracellular
                                  Targeting of Activated Erk1/2  . . . . . 1267
           Masayuki Shimizu and   
          Yasunori Murakami and   
              Fumikazu Suto and   
                Hajime Fujisawa   Determination of Cell Adhesion Sites of
                                  Neuropilin-1 . . . . . . . . . . . . . . 1283
                Yan Ping Wu and   
              Chia-Jen Siao and   
                 Weiquan Lu and   
           Tsung-Chang Sung and   
         Michael A. Frohman and   
                Peter Milev and   
            Thomas H. Bugge and   
               Jay L. Degen and   
             Joel M. Levine and   
        Richard U. Margolis and   
               Stella E. Tsirka   The Tissue Plasminogen Activator
                                  (Tpa/Plasmin) Extracellular Proteolytic
                                  System Regulates Seizure-Induced
                                  Hippocampal Mossy Fiber Outgrowth
                                  through a Proteoglycan Substrate . . . . 1295
Yolanda S. López-Boado and   
           Carole L. Wilson and   
             Lora V. Hooper and   
          Jeffrey I. Gordon and   
          Scott J. Hultgren and   
               William C. Parks   Bacterial Exposure Induces and Activates
                                  Matrilysin in Mucosal Epithelial Cells   1305


Journal of Cell Biology
Volume 149, Number 1, April, 2000

              Patrick Brennwald   Reversal of Fortune  . . . . . . . . . . ??
       Susan L. Kline-Smith and   
              Claire E. Walczak   Microtubules in orbit  . . . . . . . . . 5
          Thomas M. Roberts and   
                 Murray Stewart   Acting like Actin  . . . . . . . . . . . 7
          Shoichiro Tsukita and   
                   Mikio Furuse   Pores in the Wall  . . . . . . . . . . . 13
              Carlos Caulin and   
               Carl F. Ware and   
            Thomas M. Magin and   
               Robert G. Oshima   Keratin-Dependent, Epithelial Resistance
                                  to Tumor Necrosis Factor--Induced
                                  Apoptosis  . . . . . . . . . . . . . . . 17
            Jan Schmoranzer and   
               Mark Goulian and   
                Dan Axelrod and   
               Sanford M. Simon   Imaging Constitutive Exocytosis with
                                  Total Internal Reflection Fluorescence
                                  Microscopy . . . . . . . . . . . . . . . 23
               Derek Toomre and   
      Jürgen A. Steyer and   
             Patrick Keller and   
            Wolfhard Almers and   
                     Kai Simons   Fusion of Constitutive Membrane Traffic
                                  with the Cell Surface Observed by
                                  Evanescent Wave Microscopy . . . . . . . 33
        Symeon Siniossoglou and   
             Malik Lutzmann and   
         Helena Santos-Rosa and   
              Kevin Leonard and   
            Shirley Mueller and   
                  Ueli Aebi and   
                        Ed Hurt   Structure and Assembly of the Nup84p
                                  Complex  . . . . . . . . . . . . . . . . 41
               Xiaochun Cao and   
                Charles Barlowe   Asymmetric Requirements for a Rab Gtpase
                                  and Snare Proteins in Fusion of Copii
                                  Vesicles with Acceptor Membranes . . . . 55
             Jennifer Hirst and   
           Winnie W. Y. Lui and   
         Nicholas A. Bright and   
             Nicholas Totty and   
       Matthew N. J. Seaman and   
           Margaret S. Robinson   A Family of Proteins with $ \gamma
                                  $-Adaptin and VHS Domains That
                                  Facilitate Trafficking between the
                                  Trans-Golgi Network and the
                                  Vacuole/Lysosome . . . . . . . . . . . . 67
   Esteban C. Dell'Angelica and   
           Rosa Puertollano and   
              Chris Mullins and   
    Rubén C. Aguilar and   
      José D. Vargas and   
           Lisa M. Hartnell and   
             Juan S. Bonifacino   Ggas . . . . . . . . . . . . . . . . . . 81
            N. Barry Elkind and   
  Christiane Walch-Solimena and   
                Peter J. Novick   The Role of the COOH Terminus of Sec2p
                                  in the Transport of post-Golgi Vesicles  95
           Audra J. Charron and   
             Sakie Nakamura and   
            Robert Bacallao and   
          Angela Wandinger-Ness   Compromised Cytoarchitecture and
                                  Polarized Trafficking in Autosomal
                                  Dominant Polycystic Kidney Disease Cells 111
            Andrew Bloecher and   
                 Kelly Tatchell   Dynamic Localization of Protein
                                  Phosphatase Type 1 in the Mitotic Cell
                                  Cycle of \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 125
              Diego Peretti and   
              Leticia Peris and   
              Silvana Rosso and   
           Santiago Quiroga and   
         Alfredo Cáceres   Evidence for the Involvement of Kif4 in
                                  the Anterograde Transport of
                                  L1-Containing Vesicles . . . . . . . . . 141
         Yoshihiro H. Inoue and   
      Maria do Carmo Avides and   
            Michina Shiraki and   
                 Peter Deak and   
        Masamitsu Yamaguchi and   
           Yoshio Nishimoto and   
             Akio Matsukage and   
                David M. Glover   Orbit, a Novel Microtubule--Associated
                                  Protein Essential for Mitosis in
                                  \bionameDrosophila melanogaster  . . . . 153
           Isabelle Coppens and   
           Anthony P. Sinai and   
                Keith A. Joiner   \bionameToxoplasma gondii Exploits Host
                                  Low-Density Lipoprotein
                                  Receptor-Mediated Endocytosis for
                                  Cholesterol Acquisition  . . . . . . . . 167
            Matthias Krause and   
           Antonio S. Sechi and   
            Marlies Konradt and   
               David Monner and   
           Frank B. Gertler and   
            Jürgen Wehland   Fyn-Binding Protein
                                  (Fyb)/SLP-76-Associated Protein (SLAP),
                                  Ena/Vasodilator-Stimulated
                                  Phosphoprotein (VASP) Proteins and the
                                  Arp2/3 Complex Link T Cell Receptor
                                  (Tcr) Signaling to the Actin
                                  Cytoskeleton . . . . . . . . . . . . . . 181
     Iakowos Karakesisoglou and   
                Yanmin Yang and   
                   Elaine Fuchs   An Epidermal Plakin That Integrates
                                  Actin and Microtubule Networks at
                                  Cellular Junctions . . . . . . . . . . . 195
         Mechthild Hatzfeld and   
           Christof Haffner and   
             Katrin Schulze and   
                    Ute Vinzens   The Function of Plakophilin 1 in
                                  Desmosome Assembly and Actin Filament
                                  Organization . . . . . . . . . . . . . . 209
              Samuel Y. Cho and   
              Richard L. Klemke   Extracellular-Regulated Kinase
                                  Activation and CAS/Crk Coupling Regulate
                                  Cell Migration and Suppress Apoptosis
                                  during Invasion of the Extracellular
                                  Matrix . . . . . . . . . . . . . . . . . 223

Journal of Cell Biology
Volume 149, Number 2, April, 2000

                W. James Nelson   W(H)ither the Golgi during Mitosis?  . . 243
          Ken-Ichi Takemaru and   
                Randall T. Moon   The Transcriptional Coactivator Cbp
                                  Interacts with $ \beta $-Catenin to
                                  Activate Gene Expression . . . . . . . . 249
            Matthias Becker and   
                Elke Martin and   
            Jean Schneikert and   
             Harald F. Krug and   
              Andrew C. B. Cato   Cytoplasmic Localization and the Choice
                                  of Ligand Determine Aggregate Formation
                                  by Androgen Receptor with Amplified
                                  Polyglutamine Stretch  . . . . . . . . . 255
             Siegfried Wahl and   
               Holger Barth and   
             Thomas Ciossek and   
             Klaus Aktories and   
            Bernhard K. Mueller   Ephrin-A5 Induces Collapse of Growth
                                  Cones by Activating Rho and Rho Kinase   263
         Heinrich Leonhardt and   
            Hans-Peter Rahn and   
            Peter Weinzierl and   
              Anje Sporbert and   
              Thomas Cremer and   
               Daniele Zink and   
            M. Cristina Cardoso   Dynamics of DNA Replication Factories in
                                  Living Cells . . . . . . . . . . . . . . 271
                  Asoke Mal and   
      Debasis Chattopadhyay and   
            Mrinal K. Ghosh and   
           Randy Y. C. Poon and   
                Tony Hunter and   
               Marian L. Harter   P21 and Retinoblastoma Protein Control
                                  the Absence of DNA Replication in
                                  Terminally Differentiated Muscle Cells   281
    Céline Verheggen and   
       Genevi\`eve Almouzni and   
     Dani\`ele Hernandez-Verdun   The Ribosomal RNA Processing Machinery
                                  Is Recruited to the Nucleolar Domain
                                  before RNA Polymerase I during
                                  \bionameXenopus laevis Development . . . 293
Willemien van der Houven van Oordt and   
  María T. Diaz-Meco and   
         José Lozano and   
          Adrian R. Krainer and   
               Jorge Moscat and   
       Javier F. Cáceres   The Mkk$_{3 \slash 6}$-p38-Signaling
                                  Cascade Alters the Subcellular
                                  Distribution of Hnrnp A1 and Modulates
                                  Alternative Splicing Regulation  . . . . 307
              Matthieu Piel and   
                Pablo Meyer and   
           Alexey Khodjakov and   
            Conly L. Rieder and   
                 Michel Bornens   The Respective Contributions of the
                                  Mother and Daughter Centrioles to
                                  Centrosome Activity and Behavior in
                                  Vertebrate Cells . . . . . . . . . . . . 317
           Antonino Colanzi and   
         Thomas J. Deerinck and   
           Mark H. Ellisman and   
                 Vivek Malhotra   A Specific Activation of the
                                  Mitogen--Activated Protein Kinase Kinase
                                  1 (Mek1) Is Required for Golgi
                                  Fragmentation during Mitosis . . . . . . 331
                Martin Lowe and   
        Nicholas K. Gonatas and   
                  Graham Warren   The Mitotic Phosphorylation Cycle of the
                                  cis-Golgi Matrix Protein Gm130 . . . . . 341
                  Fumi Kano and   
           Katsuya Takenaka and   
          Akitsugu Yamamoto and   
           Kuniaki Nagayama and   
             Eisuke Nishida and   
                Masayuki Murata   Mek and Cdc2 Kinase Are Sequentially
                                  Required for Golgi Disassembly in Mdck
                                  Cells by the Mitotic \bionameXenopus
                                  Extracts . . . . . . . . . . . . . . . . 357
              Stephanie Ruf and   
              Klaus Biehler and   
                     Ralph Bock   A Small Chloroplast--Encoded Protein as
                                  a Novel Architectural Component of the
                                  Light--Harvesting Antenna  . . . . . . . 369
            David E. Krantz and   
            Clarissa Waites and   
             Viola Oorschot and   
               Yongjian Liu and   
           Rachel I. Wilson and   
              Philip K. Tan and   
          Judith Klumperman and   
              Robert H. Edwards   A Phosphorylation Site Regulates Sorting
                                  of the Vesicular Acetylcholine
                                  Transporter to Dense Core Vesicles . . . 379
         Andreas Wiederkehr and   
             Sandrine Avaro and   
Cristina Prescianotto-Baschong and   
   Rosine Haguenauer-Tsapis and   
                 Howard Riezman   The F--Box Protein Rcy1p Is Involved in
                                  Endocytic Membrane Traffic and Recycling
                                  Out of an Early Endosome in
                                  \bionameSaccharomyces cerevisiae . . . . 397
         Alyson E. Fournier and   
             Fumio Nakamura and   
            Susumu Kawamoto and   
             Yoshio Goshima and   
             Robert G. Kalb and   
        Stephen M. Strittmatter   Semaphorin3a Enhances Endocytosis at
                                  Sites of Receptor--F--Actin
                                  Colocalization during Growth Cone
                                  Collapse . . . . . . . . . . . . . . . . 411
                Hiroki Ueda and   
                 Smita Abbi and   
             Chuanhai Zheng and   
                   Jun-Lin Guan   Suppression of Pyk2 Kinase and Cellular
                                  Activities by Fip200 . . . . . . . . . . 423
          Andrew P. Gilmore and   
        Anthony D. Metcalfe and   
             Lewis H. Romer and   
             Charles H. Streuli   Integrin-Mediated Survival Signals
                                  Regulate the Apoptotic Function of Bax
                                  through Its Conformation and Subcellular
                                  Localization . . . . . . . . . . . . . . 431
               Kirill Rosen and   
                 Janusz Rak and   
               Thomas Leung and   
           Nicholas M. Dean and   
           Robert S. Kerbel and   
                   Jorge Filmus   Activated ras Prevents Downregulation of
                                  Bcl--X$_L$ Triggered by Detachment from
                                  the Extracellular Matrix . . . . . . . . 447
         Sarang V. Kulkarni and   
                Gerald Gish and   
         Peter van der Geer and   
            Mark Henkemeyer and   
                    Tony Pawson   Role of P120 Ras--Gap in Directed Cell
                                  Movement . . . . . . . . . . . . . . . . 457
          Daniel P. Kiehart and   
     Catherine G. Galbraith and   
           Kevin A. Edwards and   
           Wayne L. Rickoll and   
               Ruth A. Montague   Multiple Forces Contribute to Cell Sheet
                                  Morphogenesis for Dorsal Closure in
                                  \bionameDrosophila . . . . . . . . . . . 471
  Catherine Faivre-Sarrailh and   
            France Gauthier and   
 Natalia Denisenko-Nehrbass and   
      André Le Bivic and   
         Genevi\`eve Rougon and   
           Jean-Antoine Girault   The Glycosylphosphatidyl
                                  Inositol-Anchored Adhesion Molecule
                                  F3/Contactin Is Required for Surface
                                  Transport of
                                  Paranodin/Contactin-Associated Protein
                                  (Caspr)  . . . . . . . . . . . . . . . . 491
     Emmanuelle Charpentier and   
           Robert M. Lavker and   
         Elizabeth Acquista and   
                   Pamela Cowin   Plakoglobin Suppresses Epithelial
                                  Proliferation and Hair Growth in Vivo    503
           Sambra D. Redick and   
          Daniel L. Settles and   
               Gina Briscoe and   
             Harold P. Erickson   Defining Fibronectin's Cell Adhesion
                                  Synergy Site by Site-Directed
                                  Mutagenesis  . . . . . . . . . . . . . . 521

Journal of Cell Biology
Volume 149, Number 3, May, 2000

                    Ira Mellman   Quo Vadis: Polarized Membrane Recycling
                                  in Motility and Phagocytosis . . . . . . 529
           Rikke Lise Steen and   
          Fabien Cubizolles and   
       Katherine Le Guellec and   
                Philippe Collas   A Kinase-Anchoring Protein (Akap95)
                                  Recruits Human Chromosome-Associated
                                  Protein (Hcap--D2/Eg7) for Chromosome
                                  Condensation in Mitotic Extract  . . . . 531
                 Joel Hyman and   
                  Hong Chen and   
        Pier Paolo Di Fiore and   
          Pietro De Camilli and   
                Axel T. Brunger   Epsin 1 Undergoes Nucleocytosolic
                                  Shuttling and Its Eps15 Interactor
                                  Nh$_2$ -Terminal Homology (Enth) Domain,
                                  Structurally Similar to Armadillo and
                                  Heat Repeats, Interacts with the
                                  Transcription Factor Promyelocytic
                                  Leukemia Zn$^2$ + Finger Protein (Plzf)  537
                  Nam-On Ku and   
                 M. Bishr Omary   Keratins Turn over by Ubiquitination in
                                  a Phosphorylation--Modulated Fashion . . 547
 Soundarapandian Velmurugan and   
              Xian-Mei Yang and   
        Clarence S.-M. Chan and   
             Melanie Dobson and   
                Makkuni Jayaram   Partitioning of the 2-$ \mu $ m Circle
                                  Plasmid of \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 553
               Young-Gyu Ko and   
             Young-Sun Kang and   
             Eun-Kyoung Kim and   
              Sang Gyu Park and   
                   Sunghoon Kim   Nucleolar Localization of Human
                                  Methionyl--Trna Synthetase and Its Role
                                  in Ribosomal RNA Synthesis . . . . . . . 567
               Stephan Fath and   
          Philipp Milkereit and   
 Alexandre V. Podtelejnikov and   
           Nicolas Bischler and   
            Patrick Schultz and   
                 Mirko Bier and   
              Matthias Mann and   
             Herbert Tschochner   Association of Yeast RNA Polymerase I
                                  with a Nucleolar Substructure Active in
                                  Rrna Synthesis and Processing  . . . . . 575
      Christine D. McCallum and   
                    Hung Do and   
          Arthur E. Johnson and   
                 Judith Frydman   The Interaction of the Chaperonin
                                  Tailless Complex Polypeptide 1 (Tcp1)
                                  Ring Complex (Tric) with Ribosome--Bound
                                  Nascent Chains Examined Using
                                  Photo--Cross--Linking  . . . . . . . . . 591
              Marie Mancini and   
        Carolyn E. Machamer and   
                 Sophie Roy and   
        Donald W. Nicholson and   
        Nancy A. Thornberry and   
    Livia A. Casciola-Rosen and   
                   Antony Rosen   Caspase-2 Is Localized at the Golgi
                                  Complex and Cleaves Golgin-160 during
                                  Apoptosis  . . . . . . . . . . . . . . . 603
             Shin-Jung Kang and   
                 Suyue Wang and   
               Hideaki Hara and   
           Erin P. Peterson and   
               Shobu Namura and   
       Sepideh Amin-Hanjani and   
              Zhihong Huang and   
             Anu Srinivasan and   
         Kevin J. Tomaselli and   
        Nancy A. Thornberry and   
       Michael A. Moskowitz and   
                   Junying Yuan   Dual Role of Caspase-11 in Mediating
                                  Activation of Caspase-1 and Caspase-3
                                  under Pathological Conditions  . . . . . 613
            George Hausmann and   
       Lorraine A. O'Reilly and   
         Rosemary van Driel and   
       Jennifer G. Beaumont and   
           Andreas Strasser and   
             Jerry M. Adams and   
              David C. S. Huang   Pro-Apoptotic Apoptosis
                                  Protease--Activating Factor 1 (Apaf-1)
                                  Has a Cytoplasmic Localization Distinct
                                  from Bcl-2 or Bcl--X$_L$ . . . . . . . . 623
          Kenneth A. Taylor and   
           Dianne W. Taylor and   
                  Fred Schachat   Isoforms of $ \alpha $-Actinin from
                                  Cardiac, Smooth, and Skeletal Muscle
                                  Form Polar Arrays of Actin Filaments . . 635
         Ronald R. Dubreuil and   
                  Ping Wang and   
                 Steve Dahl and   
                   John Lee and   
       Lawrence S. B. Goldstein   Drosophila $ \beta $ Spectrin Functions
                                  Independently of $ \alpha $ Spectrin to
                                  Polarize the Na,k Atpase in Epithelial
                                  Cells  . . . . . . . . . . . . . . . . . 647
             Bret B. Friday and   
            Valerie Horsley and   
               Grace K. Pavlath   Calcineurin Activity Is Required for the
                                  Initiation of Skeletal Muscle
                                  Differentiation  . . . . . . . . . . . . 657
                  Lisa Choy and   
         Jeremy Skillington and   
                    Rik Derynck   Roles of Autocrine TGF-$ \beta $
                                  Receptor and Smad Signaling in Adipocyte
                                  Differentiation  . . . . . . . . . . . . 667
           Cedric S. Wesley and   
                      Lino Saez   Analysis of Notch Lacking the Carboxyl
                                  Terminus Identified in
                                  \bionameDrosophila Embryos . . . . . . . 683
                Lydia Bajno and   
             Xiao-Rong Peng and   
          Alan D. Schreiber and   
           Hsiao-Ping Moore and   
         William S. Trimble and   
               Sergio Grinstein   Focal Exocytosis of Vamp3-Containing
                                  Vesicles at Sites of Phagosome Formation 697
                Petr Tvrdik and   
            Rolf Westerberg and   
               Sandra Silve and   
             Abolfazl Asadi and   
          Andreas Jakobsson and   
             Barbara Cannon and   
              Gerard Loison and   
               Anders Jacobsson   Role of a New Mammalian Gene Family in
                                  the Biosynthesis of Very Long Chain
                                  Fatty Acids and Sphingolipids  . . . . . 707
         David W. Schmidtke and   
               Scott L. Diamond   Direct Observation of Membrane Tethers
                                  Formed during Neutrophil Attachment to
                                  Platelets or P--Selectin under
                                  Physiological Flow . . . . . . . . . . . 719
              Hans Reinecke and   
          Glen H. MacDonald and   
        Stephen D. Hauschka and   
               Charles E. Murry   Electromechanical Coupling between
                                  Skeletal and Cardiac Muscle  . . . . . . 731
      Eduardo A. C. Almeida and   
             Du\vsko Ili\'c and   
                    Qin Han and   
          Christof R. Hauck and   
                   Fang Jin and   
          Hisaaki Kawakatsu and   
        David D. Schlaepfer and   
             Caroline H. Damsky   Matrix Survival Signaling  . . . . . . . 741

Journal of Cell Biology
Volume 149, Number 4, May, 2000

                Urs Rutishauser   Defining a Role and Mechanism for Igcam
                                  Function in Vertebrate Axon Guidance . . 757
       Jennifer S. Tirnauer and   
              Barbara E. Bierer   Eb1 Proteins Regulate Microtubule
                                  Dynamics, Cell Polarity, and Chromosome
                                  Stability  . . . . . . . . . . . . . . . 761
             Isabelle Arnal and   
              Eric Karsenti and   
               Anthony A. Hyman   Structural Transitions at Microtubule
                                  Ends Correlate with Their Dynamic
                                  Properties in \bionameXenopus Egg
                                  Extracts . . . . . . . . . . . . . . . . 767
        Gerben C. M. Zondag and   
               Eva E. Evers and   
       Jean P. ten Klooster and   
            Lennert Janssen and   
      Rob A. van der Kammen and   
                John G. Collard   Oncogenic Ras Downregulates Rac
                                  Activity, Which Leads to Increased Rho
                                  Activity and Epithelial--Mesenchymal
                                  Transition . . . . . . . . . . . . . . . 775
              Xiang-ping He and   
                  Feng Yang and   
               Zuo-ping Xie and   
                         Bai Lu   Intracellular Ca$^{2+}$ and Ca$^{2+}$
                                  /Calmodulin--Dependent Kinase II Mediate
                                  Acute Potentiation of Neurotransmitter
                                  Release by Neurotrophin-3  . . . . . . . 783
       Malcolm A. Leissring and   
                Yama Akbari and   
      Christopher M. Fanger and   
         Michael D. Cahalan and   
            Mark P. Mattson and   
               Frank M. LaFerla   Capacitative Calcium Entry Deficits and
                                  Elevated Luminal Calcium Content in
                                  Mutant Presenilin-1 Knockin Mice . . . . 793
              Yaron Daniely and   
              James A. Borowiec   Formation of a Complex between Nucleolin
                                  and Replication Protein a after Cell
                                  Stress Prevents Initiation of DNA
                                  Replication  . . . . . . . . . . . . . . 799
               Lita Freeman and   
        Luis Aragon-Alcaide and   
           Alexander Strunnikov   The Condensin Complex Governs Chromosome
                                  Condensation and Mitotic Transmission of
                                  Rdna . . . . . . . . . . . . . . . . . . 811
          Jacquelyn Gerhart and   
            Michael Baytion and   
              Steven DeLuca and   
               Robert Getts and   
            Christian Lopez and   
          Robert Niewenhuis and   
                Thor Nilsen and   
                 Scott Olex and   
           Harold Weintraub and   
         Mindy George-Weinstein   DNA Dendrimers Localize Myod mRNA in
                                  Presomitic Tissues of the Chick Embryo   825
        Michael E. Nemergut and   
                  Ian G. Macara   Nuclear Import of the Ran Exchange
                                  Factor, Rcc1, Is Mediated by at Least
                                  Two Distinct Mechanisms  . . . . . . . . 835
             Andreas Merdes and   
              Rebecca Heald and   
            Kumiko Samejima and   
        William C. Earnshaw and   
               Don W. Cleveland   Formation of Spindle Poles by
                                  Dynein/Dynactin-Dependent Transport of
                                  Numa . . . . . . . . . . . . . . . . . . 851
             Neil R. Adames and   
                 John A. Cooper   Microtubule Interactions with the Cell
                                  Cortex Causing Nuclear Movements in
                                  \bionameSaccharomyces cerevisiae . . . . 863
               Holger Knaut and   
          Francisco Pelegri and   
            Kerstin Bohmann and   
              Heinz Schwarz and   
Christiane Nüsslein-Volhard   Zebrafish vasa RNA but Not Its Protein
                                  Is a Component of the Germ Plasm and
                                  Segregates Asymmetrically before
                                  Germline Specification . . . . . . . . . 875
        Sonia Martinez-Arca and   
            Philipp Alberts and   
             Ahmed Zahraoui and   
             Daniel Louvard and   
                  Thierry Galli   Role of Tetanus Neurotoxin Insensitive
                                  Vesicle--Associated Membrane Protein
                                  (Ti--Vamp) in Vesicular Transport
                                  Mediating Neurite Outgrowth  . . . . . . 889
      Birte Sönnichsen and   
          Stefano De Renzis and   
               Erik Nielsen and   
              Jens Rietdorf and   
                  Marino Zerial   Distinct Membrane Domains on Endosomes
                                  in the Recycling Pathway Visualized by
                                  Multicolor Imaging of Rab4, Rab5, and
                                  Rab11  . . . . . . . . . . . . . . . . . 901
              Suraj Moorthy and   
                Lihsia Chen and   
                   Vann Bennett   \bionameCaenorhabditis elegans $ \beta
                                  $-G Spectrin Is Dispensable for
                                  Establishment of Epithelial Polarity,
                                  but Essential for Muscular and Neuronal
                                  Function . . . . . . . . . . . . . . . . 915
            Marc Hammarlund and   
            Warren S. Davis and   
              Erik M. Jorgensen   Mutations in $ \beta $-Spectrin Disrupt
                                  Axon Outgrowth and Sarcomere Structure   931
          Takayuki Kanazawa and   
           Sachiko Nakamura and   
              Michiko Momoi and   
           Toshiyuki Yamaji and   
           Hiromu Takematsu and   
                Hajime Yano and   
              Hisataka Sabe and   
          Akitsugu Yamamoto and   
         Toshisuke Kawasaki and   
             Yasunori Kozutsumi   Inhibition of Cytokinesis by a Lipid
                                  Metabolite, Psychosine . . . . . . . . . 943
                Dora Fitzli and   
         Esther T. Stoeckli and   
                Stefan Kunz and   
          Kingsley Siribour and   
            Christoph Rader and   
                  Beat Kunz and   
          Serguei V. Kozlov and   
         Andrea Buchstaller and   
             Robert P. Lane and   
            Daniel M. Suter and   
          William J. Dreyer and   
              Peter Sonderegger   A Direct Interaction of Axonin-1 with
                                  Ngcam--Related Cell Adhesion Molecule
                                  (Nrcam) Results in Guidance, but Not
                                  Growth of Commissural Axons  . . . . . . 951
         Lotus M. Th. Sterk and   
       Cecile A. W. Geuijen and   
      Lauran C. J. M. Oomen and   
               Jero Calafat and   
               Hans Janssen and   
              Arnoud Sonnenberg   The Tetraspan Molecule Cd151, a Novel
                                  Constituent of Hemidesmosomes,
                                  Associates with the Integrin $ \alpha
                                  $6$ \beta $4 and May Regulate the
                                  Spatial Organization of Hemidesmosomes   969
         Catherine J. Gress and   
                  Olena Jacenko   Growth Plate Compressions and Altered
                                  Hematopoiesis in Collagen X Null Mice    983

Journal of Cell Biology
Volume 149, Number 5, May, 2000

              Alan C. Rapraeger   Syndecan-Regulated Receptor Signaling    995
         Charles K. Kaufman and   
                   Elaine Fuchs   It's Got You Covered . . . . . . . . . . 999
                     Ye Jin and   
               Yanming Wang and   
     Jòrgen Johansen and   
            Kristen M. Johansen   Jil-1, a Chromosomal Kinase Implicated
                                  in Regulation of Chromatin Structure,
                                  Associates with the Male Specific Lethal
                                  (Msl) Dosage Compensation Complex  . . . 1005
           Girish V. Putcha and   
          Mohanish Deshmukh and   
              Eugene M. Johnson   Inhibition of Apoptotic Signaling
                                  Cascades Causes Loss of Trophic Factor
                                  Dependence during Neuronal Maturation    1011
               Lucio Gnessi and   
           Sabrina Basciani and   
           Stefania Mariani and   
               Mario Arizzi and   
             Giovanni Spera and   
              Chiayeng Wang and   
           Cecilia Bondjers and   
             Linda Karlsson and   
             Christer Betsholtz   Leydig Cell Loss and Spermatogenic
                                  Arrest in Platelet--Derived Growth
                                  Factor (Pdgf)--a--Deficient Mice . . . . 1019
            Nataliya Shulga and   
         Nima Mosammaparast and   
            Richard Wozniak and   
              David S. Goldfarb   Yeast Nucleoporins Involved in Passive
                                  Nuclear Envelope Permeability  . . . . . 1027
             Tadashi Suzuki and   
                Hangil Park and   
     Nancy M. Hollingsworth and   
            Rolf Sternglanz and   
             William J. Lennarz   PNG1, a Yeast Gene Encoding a Highly
                                  Conserved Peptide: N -Glycanase  . . . . 1039
              Paul R. Pryor and   
         Barbara M. Mullock and   
         Nicholas A. Bright and   
              Sally R. Gray and   
                  J. Paul Luzio   The Role of Intraorganellar Ca$^{2+}$ In
                                  Late Endosome--Lysosome Heterotypic
                                  Fusion and in the Reformation of
                                  Lysosomes from Hybrid Organelles . . . . 1053
               Thomas Weber and   
          Francesco Parlati and   
             James A. McNew and   
         Robert J. Johnston and   
        Benedikt Westermann and   
     Thomas H. Söllner and   
               James E. Rothman   Snarepins Are Functionally Resistant to
                                  Disruption by Nsf and $ \alpha $SNAP . . 1063
                Toru Hirota and   
           Tetsuro Morisaki and   
         Yasuyuki Nishiyama and   
         Tomotoshi Marumoto and   
                 Kenji Tada and   
             Toshihiro Hara and   
               Norio Masuko and   
             Masaki Inagaki and   
      Katsuyoshi Hatakeyama and   
                  Hideyuki Saya   Zyxin, a Regulator of Actin Filament
                                  Assembly, Targets the Mitotic Apparatus
                                  by Interacting with H-Warts/Lats1 Tumor
                                  Suppressor . . . . . . . . . . . . . . . 1073
     Arunashree Bhamidipati and   
             Sally A. Lewis and   
              Nicholas J. Cowan   Adp Ribosylation Factor-like Protein 2
                                  (Arl2) Regulates the Interaction of
                                  Tubulin--Folding Cofactor D with Native
                                  Tubulin  . . . . . . . . . . . . . . . . 1087
                     Lu Xia and   
                   Bing Hai and   
                    Yan Gao and   
             Dylan Burnette and   
             Rupal Thazhath and   
              Jianming Duan and   
    Marie-Helene Bré and   
       Nicolette Levilliers and   
         Martin A. Gorovsky and   
                  Jacek Gaertig   Polyglycylation of Tubulin Is Essential
                                  and Affects Cell Motility and Division
                                  in \bionameTetrahymena thermophila . . . 1097
               Julie Y. Pan and   
          William E. Fieles and   
              Anne M. White and   
            Mark M. Egerton and   
           David S. Silberstein   Ges, a Human GTPase of the Rad/Gem/Kir
                                  Family, Promotes Endothelial Cell
                                  Sprouting and Cytoskeleton
                                  Reorganization . . . . . . . . . . . . . 1107
            Elena Dellambra and   
           Osvaldo Golisano and   
            Sergio Bondanza and   
           Emanuela Siviero and   
                Pedro Lacal and   
             Marta Molinari and   
            Stefania D'Atri and   
                Michele De Luca   Downregulation of 14-3-3$ \sigma $
                                  Prevents Clonal Evolution and Leads to
                                  Immortalization of Primary Human
                                  Keratinocytes  . . . . . . . . . . . . . 1117
          Bridget S. Wilson and   
          Janet R. Pfeiffer and   
                Janet M. Oliver   Observing Fc$ \epsilon $ ri Signaling
                                  from the Inside of the Mast Cell
                                  Membrane . . . . . . . . . . . . . . . . 1131
                Kousuke Iba and   
         Reidar Albrechtsen and   
               Brent Gilpin and   
      Camilla Fröhlich and   
             Frosty Loechel and   
            Anna Zolkiewska and   
          Kazuhiro Ishiguro and   
           Tetsuhito Kojima and   
                    Wei Liu and   
          J. Kevin Langford and   
         Ralph D. Sanderson and   
            Cord Brakebusch and   
      Reinhard Fässler and   
                  Ulla M. Wewer   The Cysteine--Rich Domain of Human Adam
                                  12 Supports Cell Adhesion through
                                  Syndecans and Triggers Signaling Events
                                  That Lead to $ \beta $1
                                  Integrin--Dependent Cell Spreading . . . 1143
        Katerina Akassoglou and   
         Keith W. Kombrinck and   
               Jay L. Degen and   
              Sidney Strickland   Tissue Plasminogen Activator-Mediated
                                  Fibrinolysis Protects against Axonal
                                  Degeneration and Demyelination after
                                  Sciatic Nerve Injury . . . . . . . . . . 1157

Journal of Cell Biology
Volume 149, Number 6, June, 2000

                  Vito Quaranta   Cell Migration through Extracellular
                                  Matrix . . . . . . . . . . . . . . . . . 1167
          William B. Snyder and   
            Antonius Koller and   
               A. Jobu Choy and   
               Suresh Subramani   The Peroxin Pex19p Interacts with
                                  Multiple, Integral Membrane Proteins at
                                  the Peroxisomal Membrane . . . . . . . . 1171
             Robert D. Moir and   
           Timothy P. Spann and   
            Harald Herrmann and   
              Robert D. Goldman   Disruption of Nuclear Lamin Organization
                                  Blocks the Elongation Phase of DNA
                                  Replication  . . . . . . . . . . . . . . 1179
         Masakiyo Sakaguchi and   
          Masahiro Miyazaki and   
               Yusuke Inoue and   
              Toshiya Tsuji and   
            Hirosuke Kouchi and   
              Toshio Tanaka and   
            Hidenori Yamada and   
                Masayoshi Namba   Relationship between Contact Inhibition
                                  and Intranuclear S100c of Normal Human
                                  Fibroblasts  . . . . . . . . . . . . . . 1193
                Kurt De Vos and   
              Fedor Severin and   
      Franky Van Herreweghe and   
       Katia Vancompernolle and   
              Vera Goossens and   
              Anthony Hyman and   
                  Johan Grooten   Tumor Necrosis Factor Induces
                                  Hyperphosphorylation of Kinesin Light
                                  Chain and Inhibits Kinesin-Mediated
                                  Transport of Mitochondria  . . . . . . . 1207
                Kazuo Emoto and   
                   Masato Umeda   An Essential Role for a Membrane Lipid
                                  in Cytokinesis . . . . . . . . . . . . . 1215
         Thorsten Hornemann and   
               Martin Stolz and   
                 Theo Wallimann   Isoenzyme-Specific Interaction of
                                  Muscle--Type Creatine Kinase with the
                                  Sarcomeric M--Line Is Mediated by Nh$_2$
                                  -Terminal Lysine Charge--Clamps  . . . . 1225
       H. Llewelyn Roderick and   
        James D. Lechleiter and   
               Patricia Camacho   Cytosolic Phosphorylation of Calnexin
                                  Controls Intracellular Ca$^{2+}$
                                  Oscillations via an Interaction with
                                  Serca2b  . . . . . . . . . . . . . . . . 1235
               David Sancho and   
                Marta Nieto and   
               Manuel Llano and   
José L. Rodríguez-Fernández and   
              Reyes Tejedor and   
             Shalom Avraham and   
      Carlos Cabañas and   
  Miguel López-Botet and   
Francisco Sánchez-Madrid   The Tyrosine Kinase Pyk-2/Raftk
                                  Regulates Natural Killer (Nk) Cell
                                  Cytotoxic Response, and Is Translocated
                                  and Activated upon Specific Target Cell
                                  Recognition and Killing  . . . . . . . . 1249
             Carlos Arregui and   
             Purnima Pathre and   
                Jack Lilien and   
                  Janne Balsamo   The Nonreceptor Tyrosine Kinase Fer
                                  Mediates Cross--Talk between N--Cadherin
                                  and $ \beta $1-Integrins . . . . . . . . 1263
                  Hedong Li and   
            Tin-Chung Leung and   
            Stanley Hoffman and   
              Janne Balsamo and   
                    Jack Lilien   Coordinate Regulation of Cadherin and
                                  Integrin Function by the Chondroitin
                                  Sulfate Proteoglycan Neurocan  . . . . . 1275
            Brent J. Miller and   
Elisabeth Georges-Labouesse and   
             Paul Primakoff and   
                 Diana G. Myles   Normal Fertilization Occurs with Eggs
                                  Lacking the Integrin $ \alpha $6$ \beta
                                  $1 and Is Cd9-Dependent  . . . . . . . . 1289
            Alka Mansukhani and   
             Paola Bellosta and   
               Malika Sahni and   
               Claudio Basilico   Signaling by Fibroblast Growth Factors
                                  (Fgf) and Fibroblast Growth Factor
                                  Receptor 2 (Fgfr2)--Activating Mutations
                                  Blocks Mineralization and Induces
                                  Apoptosis in Osteoblasts . . . . . . . . 1297
               Kevin Hotary and   
               Edward Allen and   
       Antonello Punturieri and   
                  Ikuo Yana and   
               Stephen J. Weiss   Regulation of Cell Invasion and
                                  Morphogenesis in a Three--Dimensional
                                  Type I Collagen Matrix by Membrane--Type
                                  Matrix Metalloproteinases 1, 2, and 3    1309

Journal of Cell Biology
Volume 149, Number 7, June, 2000

                   Feng Wei and   
                  Zao C. Xu and   
                  Zhican Qu and   
          Jeffrey Milbrandt and   
                       Min Zhuo   Role of Egr1 in Hippocampal Synaptic
                                  Enhancement Induced by Tetanic
                                  Stimulation and Amputation . . . . . . . 1325
            Sharif U. Ahmed and   
               Enrique Rojo and   
         Valentina Kovaleva and   
       Sridhar Venkataraman and   
        James E. Dombrowski and   
               Ken Matsuoka and   
             Natasha V. Raikhel   The Plant Vacuolar Sorting Receptor
                                  Atelp Is Involved in Transport of Nh$_2$
                                  -Terminal Propeptide--Containing
                                  Vacuolar Proteins in Arabidopsis
                                  thaliana . . . . . . . . . . . . . . . . 1335
             Sarah T. South and   
    Katherine A. Sacksteder and   
                Xiaoling Li and   
                  Yifei Liu and   
               Stephen J. Gould   Inhibitors of COPI and COPII Do Not
                                  Block PEX3-Mediated Peroxisome Synthesis 1345
             Adam D. Rudner and   
          Kevin G. Hardwick and   
               Andrew W. Murray   Cdc28 Activates Exit from Mitosis in
                                  Budding Yeast  . . . . . . . . . . . . . 1361
             Adam D. Rudner and   
               Andrew W. Murray   Phosphorylation by Cdc28 Activates the
                                  Cdc20-Dependent Activity of the
                                  Anaphase--Promoting Complex  . . . . . . 1377
     Verena Jantsch-Plunger and   
         Pierre Gönczy and   
               Alper Romano and   
            Heinke Schnabel and   
            Danielle Hamill and   
              Ralf Schnabel and   
           Anthony A. Hyman and   
                Michael Glotzer   Cyk-4  . . . . . . . . . . . . . . . . . 1391
           Torsten Wittmann and   
              Matthias Wilm and   
              Eric Karsenti and   
                Isabelle Vernos   Tpx2, a Novel \bionameXenopus Map
                                  Involved in Spindle Pole Organization    1405
               Ute Schaeper and   
           Niels H. Gehring and   
             Klaus P. Fuchs and   
               Martin Sachs and   
            Bettina Kempkes and   
              Walter Birchmeier   Coupling of Gab1 to C--Met, Grb2, and
                                  Shp2 Mediates Biological Responses . . . 1419
           Monica A. Torres and   
                W. James Nelson   Colocalization and Redistribution of
                                  Dishevelled and Actin during
                                  WNT--Induced Mesenchymal Morphogenesis   1433
                 Dunja Frey and   
              Thorsten Laux and   
                     Lan Xu and   
          Corinna Schneider and   
                    Pico Caroni   Shared and Unique Roles of Cap23 and
                                  Gap43 in Actin Regulation, Neurite
                                  Outgrowth, and Anatomical Plasticity . . 1443
              Thorsten Laux and   
              Kiyoko Fukami and   
              Marcus Thelen and   
               Tamara Golub and   
                 Dunja Frey and   
                    Pico Caroni   Gap43, Marcks, and Cap23 Modulate
                                  Pi(4,5)p$_2$ at Plasmalemmal Rafts, and
                                  Regulate Cell Cortex Actin Dynamics
                                  through a Common Mechanism . . . . . . . 1455
            Pamela J. Plant and   
               Frank Lafont and   
               Sandra Lecat and   
               Paul Verkade and   
                 Kai Simons and   
                  Daniela Rotin   Apical Membrane Targeting of Nedd4 Is
                                  Mediated by an Association of Its C2
                                  Domain with Annexin Xiiib  . . . . . . . 1473
             Steve Silletti and   
                   Fang Mei and   
              Dean Sheppard and   
       Anthony M. P. Montgomery   Plasmin-Sensitive Dibasic Sequences in
                                  the Third Fibronectin-like Domain of
                                  L1--Cell Adhesion Molecule (Cam)
                                  Facilitate Homomultimerization and
                                  Concomitant Integrin Recruitment . . . . 1485
              Paul D. Lampe and   
          Erica M. TenBroek and   
              Janis M. Burt and   
            Wendy E. Kurata and   
            Ross G. Johnson and   
                    Alan F. Lau   Phosphorylation of Connexin43 on
                                  Serine368 by Protein Kinase C Regulates
                                  Gap Junctional Communication . . . . . . 1503
            Nathalie Rouach and   
          Jacques Glowinski and   
               Christian Giaume   Activity-Dependent Neuronal Control of
                                  Gap--Junctional Communication in
                                  Astrocytes . . . . . . . . . . . . . . . 1513


Journal of Cell Biology
Volume 150, Number 1, July, 2000

        Lindsay S. Shopland and   
             Jeanne B. Lawrence   Seeking Common Ground in Nuclear
                                  Complexity . . . . . . . . . . . . . . . ??
               Douglas R. Green   Apoptosis and Sphingomyelin Hydrolysis   ??
            Michael D. Schaller   Unc112 . . . . . . . . . . . . . . . . . ??
                 Ronald D. Vale   Aaa Proteins . . . . . . . . . . . . . . ??
          Jennifer K. Yucel and   
         Janet D. Marszalek and   
        J. Richard McIntosh and   
   Lawrence S. B. Goldstein and   
           Don W. Cleveland and   
       Alastair Valentine Philp   CENP-meta, an Essential Kinetochore
                                  Kinesin Required for the Maintenance of
                                  Metaphase Chromosome Alignment in
                                  \bionameDrosophila . . . . . . . . . . . ??
       Charlotte A. Spencer and   
         Michael J. Kruhlak and   
         Heather L. Jenkins and   
                 Xuejun Sun and   
          David P. Bazett-Jones   Mitotic Transcription Repression in Vivo
                                  in the Absence of Nucleosomal Chromatin
                                  Condensation . . . . . . . . . . . . . . 13
           Masahiro Iwamoto and   
          Yoshinobu Higuchi and   
                Eiki Koyama and   
     Motomi Enomoto-Iwamoto and   
              Kojiro Kurisu and   
                 Helena Yeh and   
          William R. Abrams and   
            Joel Rosenbloom and   
              Maurizio Pacifici   Transcription Factor Erg Variants and
                                  Functional Diversification of
                                  Chondrocytes during Limb Long Bone
                                  Development  . . . . . . . . . . . . . . 27
         Michael J. Kruhlak and   
            Melody A. Lever and   
           Wolfgang Fischle and   
                Eric Verdin and   
      David P. Bazett-Jones and   
             Michael J. Hendzel   Reduced Mobility of the Alternate
                                  Splicing Factor (Asf) through the
                                  Nucleoplasm and Steady State Speckle
                                  Compartments . . . . . . . . . . . . . . 41
                David Raden and   
                Weiqun Song and   
                   Reid Gilmore   Role of the Cytoplasmic Segments of
                                  Sec61$ \alpha $ in the Ribosome--Binding
                                  and Translocation--Promoting Activities
                                  of the Sec61 Complex . . . . . . . . . . 53
           C. Randell Brown and   
          Jameson A. McCann and   
                Hui-Ling Chiang   The Heat Shock Protein Ssa2p Is Required
                                  for Import of
                                  Fructose-1,6-Bisphosphatase into Vid
                                  Vesicles . . . . . . . . . . . . . . . . 65
             Davis T. W. Ng and   
              Eric D. Spear and   
                   Peter Walter   The Unfolded Protein Response Regulates
                                  Multiple Aspects of Secretory and
                                  Membrane Protein Biogenesis and
                                  Endoplasmic Reticulum Quality Control    77
           Christelle Alory and   
               William E. Balch   Molecular Basis for Rab Prenylation  . . 89
             James A. McNew and   
               Thomas Weber and   
          Francesco Parlati and   
         Robert J. Johnston and   
            Thomas J. Melia and   
     Thomas H. Söllner and   
               James E. Rothman   Close Is Not Enough  . . . . . . . . . . 105
          Harald Hölzl and   
           Barbara Kapelari and   
           Josef Kellermann and   
       Erika Seemüller and   
Máté Sümegi and   
              Andor Udvardy and   
               Ohad Medalia and   
            Joseph Sperling and   
     Shirley A. Müller and   
              Andreas Engel and   
            Wolfgang Baumeister   The Regulatory Complex of
                                  \bionameDrosophila melanogaster 26s
                                  Proteasomes  . . . . . . . . . . . . . . 119
          Mohanish Deshmukh and   
              Keisuke Kuida and   
              Eugene M. Johnson   Caspase Inhibition Extends the
                                  Commitment to Neuronal Death Beyond
                                  Cytochrome c Release to the Point of
                                  Mitochondrial Depolarization . . . . . . 131
            Kenneth N. Fish and   
           Sandra L. Schmid and   
                    Hanna Damke   Evidence That Dynamin-2 Functions as a
                                  Signal--Transducing Gtpase . . . . . . . 145
         Annemiek D. Tepper and   
                Paula Ruurs and   
            Therese Wiedmer and   
              Peter J. Sims and   
               Jannie Borst and   
        Wim J. van Blitterswijk   Sphingomyelin Hydrolysis to Ceramide
                                  during the Execution Phase of Apoptosis
                                  Results from Phospholipid Scrambling and
                                  Alters Cell--Surface Morphology  . . . . 155
            Steven Ackerley and   
         Andrew J. Grierson and   
            Janet Brownlees and   
             Paul Thornhill and   
          Brian H. Anderton and   
             P. Nigel Leigh and   
        Christopher E. Shaw and   
       Christopher C. J. Miller   Glutamate Slows Axonal Transport of
                                  Neurofilaments in Transfected Neurons    165
    Lilly Y. W. Bourguignon and   
                 Hongbo Zhu and   
                 Lijun Shao and   
                   Yue Wei Chen   Ankyrin--Tiam1 Interaction Promotes Rac1
                                  Signaling and Metastatic Breast Tumor
                                  Cell Invasion and Migration  . . . . . . 177
            Alexis Gautreau and   
             Daniel Louvard and   
                  Monique Arpin   Morphogenic Effects of Ezrin Require a
                                  Phosphorylation--Induced Transition from
                                  Oligomers to Monomers at the Plasma
                                  Membrane . . . . . . . . . . . . . . . . 193
             Christi Weston and   
                  Barry Yee and   
                  Eldad Hod and   
                    Joav Prives   Agrin-Induced Acetylcholine Receptor
                                  Clustering Is Mediated by the Small
                                  Guanosine Triphosphatases Rac and Cdc42  205
           Orit Aharonovitz and   
               Hans C. Zaun and   
                Tamas Balla and   
               John D. York and   
              John Orlowski and   
               Sergio Grinstein   Intracellular Ph Regulation by Na$^+$
                                  /H$^+$ Exchange Requires
                                  Phosphatidylinositol 4,5-Bisphosphate    213
         Toshihiko Toyofuku and   
                 Zhang Hong and   
           Tsunehiko Kuzuya and   
             Michihiko Tada and   
                 Masatsugu Hori   WNT\slash Frizzled-2 Signaling Induces
                                  Aggregation and Adhesion among Cardiac
                                  Myocytes by Increased Cadherin-$ \beta
                                  $-Catenin Complex  . . . . . . . . . . . 225
                    Li Tian and   
            Henrietta Nyman and   
          Patrick Kilgannon and   
        Yoshihiro Yoshihara and   
               Kensaku Mori and   
          Leif C. Andersson and   
              Sami Kaukinen and   
             Heikki Rauvala and   
        W. Michael Gallatin and   
               Carl G. Gahmberg   Intercellular Adhesion Molecule-5
                                  Induces Dendritic Outgrowth by
                                  Homophilic Adhesion  . . . . . . . . . . 243
         Teresa M. Rogalski and   
          Gregory P. Mullen and   
            Mary M. Gilbert and   
       Benjamin D. Williams and   
              Donald G. Moerman   The UNC-112 Gene in
                                  \bionameCaenorhabditis elegans Encodes a
                                  Novel Component of Cell--Matrix Adhesion
                                  Structures Required for Integrin
                                  Localization in the Muscle Cell Membrane 253
            Anna von Mikecz and   
             Suisheng Zhang and   
              Marc Montminy and   
                 Eng M. Tan and   
                Peter Hemmerich   Creb-Binding Protein (Cbp/P300) and RNA
                                  Polymerase II Colocalize in
                                  Transcriptionally Active Domains in the
                                  Nucleus  . . . . . . . . . . . . . . . . 265
   Laurent Créancier and   
          Dominique Morello and   
            Pascale Mercier and   
           Anne-Catherine Prats   Fibroblast Growth Factor 2 Internal
                                  Ribosome Entry Site (Ires) Activity Ex
                                  Vivo and in Transgenic Mice Reveals a
                                  Stringent Tissue--Specific Regulation    275

Journal of Cell Biology
Volume 150, Number 2, July, 2000

                    Ira Mellman   Genomics Comes to Cell Biology . . . . . 1
            Mark E. Fortini and   
          Marian P. Skupski and   
            Mark S. Boguski and   
             Iswar K. Hariharan   A Survey of Human Disease Gene
                                  Counterparts in the \bionameDrosophila
                                  Genome . . . . . . . . . . . . . . . . . ??
           Jeff J. Sekelsky and   
         Michael H. Brodsky and   
              Kenneth C. Burtis   DNA Repair in \bionameDrosophila . . . . ??
           Stephen M. Mount and   
                  Helen K. Salz   Pre-Messenger RNA Processing Factors in
                                  the \bionameDrosophila Genome  . . . . . ??
            Norikazu Aoyagi and   
             David A. Wassarman   Genes Encoding \bionameDrosophila
                                  melanogaster RNA Polymerase II General
                                  Transcription Factors  . . . . . . . . . ??
                     Paul Lasko   The \bionameDrosophila melanogaster
                                  Genome . . . . . . . . . . . . . . . . . ??
        Deborah K. Morrison and   
         Monica S. Murakami and   
                 Vaughn Cleghon   Protein Kinases and Phosphatases in the
                                  \bionameDrosophila Genome  . . . . . . . ??
   Lawrence S. B. Goldstein and   
           Shermali Gunawardena   Flying through the \bionameDrosophila
                                  Cytoskeletal Genome  . . . . . . . . . . ??
       Stephanie Y. Vernooy and   
           Jeffrey Copeland and   
             Nazli Ghaboosi and   
            Erik E. Griffin and   
                Soon Ji Yoo and   
                   Bruce A. Hay   Cell Death Regulation in
                                  \bionameDrosophila . . . . . . . . . . . ??
              J. Troy Littleton   A Genomic Analysis of Membrane
                                  Trafficking and Neurotransmitter Release
                                  in \bionameDrosophila  . . . . . . . . . ??
               Thomas Brody and   
                Anibal Cravchik   Drosophila melanogaster G
                                  Protein--Coupled Receptors . . . . . . . ??
           Richard O. Hynes and   
                        Qi Zhao   The Evolution of Cell Adhesion . . . . . ??
            Satoshi Tashiro and   
             Joachim Walter and   
            Akira Shinohara and   
               Nanao Kamada and   
                  Thomas Cremer   Rad51 Accumulation at Sites of DNA
                                  Damage and in Postreplicative Chromatin  283
                 S. Homburg and   
                L. Visochek and   
                   N. Moran and   
                 F. Dantzer and   
                   E. Priel and   
                 E. Asculai and   
                D. Schwartz and   
                  V. Rotter and   
                   N. Dekel and   
                 M. Cohen-Armon   A Fast Signal--Induced Activation of
                                  Poly(Adp--Ribose) Polymerase . . . . . . 293
               Tim McGarvey and   
           Emanuel Rosonina and   
            Susan McCracken and   
                    Qiyu Li and   
               Ramy Arnaout and   
             Edwin Mientjes and   
       Jeffrey A. Nickerson and   
                  Don Awrey and   
            Jack Greenblatt and   
            Gerard Grosveld and   
           Benjamin J. Blencowe   The Acute Myeloid Leukemia--Associated
                                  Protein, Dek, Forms a
                                  Splicing--Dependent Interaction with
                                  Exon--Product Complexes  . . . . . . . . 309
        Delphine Lechardeur and   
              Luke Drzymala and   
                Manu Sharma and   
               Danuta Zylka and   
              Robert Kinach and   
               Joanna Pacia and   
          Christopher Hicks and   
              Nawaid Usmani and   
         Johanna M. Rommens and   
              Gergely L. Lukacs   Determinants of the Nuclear Localization
                                  of the Heterodimeric DNA Fragmentation
                                  Factor (Icad/Cad)  . . . . . . . . . . . 321
               Saadi Ghatan and   
             Stephen Larner and   
          Yoshito Kinoshita and   
              Michal Hetman and   
                Leena Patel and   
                Zhengui Xia and   
           Richard J. Youle and   
            Richard S. Morrison   p38 Map Kinase Mediates Bax
                                  Translocation in Nitric Oxide--Induced
                                  Apoptosis in Neurons . . . . . . . . . . 335
            Norman R. Watts and   
             Dan L. Sackett and   
               Rita D. Ward and   
             Mill W. Miller and   
          Paul T. Wingfield and   
           Stephen S. Stahl and   
             Alasdair C. Steven   HIV-1 Rev Depolymerizes Microtubules to
                                  Form Stable Bilayered Rings  . . . . . . 349
      Clare Waterman-Storer and   
              Devin Y. Duey and   
              Kari L. Weber and   
                 John Keech and   
          Richard E. Cheney and   
               E. D. Salmon and   
              William M. Bement   Microtubules Remodel Actomyosin Networks
                                  in \bionameXenopus Egg Extracts via Two
                                  Mechanisms of F--Actin Transport . . . . 361
           Gian-Carlo Ochoa and   
        Vladimir I. Slepnev and   
                  Lynn Neff and   
             Niels Ringstad and   
                Kohji Takei and   
             Laurie Daniell and   
                 Warren Kim and   
                   Hong Cao and   
               Mark McNiven and   
               Roland Baron and   
              Pietro De Camilli   A Functional Link between Dynamin and
                                  the Actin Cytoskeleton at Podosomes  . . 377
           Christine Hunter and   
                 Eric Wieschaus   Regulated Expression of nullo Is
                                  Required for the Formation of Distinct
                                  Apical and Basal Adherens Junctions in
                                  the \bionameDrosophila Blastoderm  . . . 391

Journal of Cell Biology
Volume 150, Number 3, August, 2000

             Bruce D. Trapp and   
                Grahame J. Kidd   Axo-Glial Septate Junctions  . . . . . . 1
              Ying-Hao Chou and   
              Robert D. Goldman   Intermediate Filaments on the Move . . . ??
                 Ana Losada and   
             Tomoki Yokochi and   
            Ryuji Kobayashi and   
                 Tatsuya Hirano   Identification and Characterization of
                                  Sa/Scc3p Subunits in the \bionameXenopus
                                  and Human Cohesin Complexes  . . . . . . 405
              Carol Johnson and   
            Dragan Primorac and   
          Monique McKinstry and   
                John McNeil and   
                 David Rowe and   
        Jeanne Bentley Lawrence   Tracking Col1a1 RNA in Osteogenesis
                                  Imperfecta . . . . . . . . . . . . . . . 417
             Miroslav Dundr and   
                Tom Misteli and   
               Mark O. J. Olson   The Dynamics of Postmitotic Reassembly
                                  of the Nucleolus . . . . . . . . . . . . 433
        Rajendra K. Agrawal and   
      Christian M. T. Spahn and   
              Pawel Penczek and   
        Robert A. Grassucci and   
           Knud H. Nierhaus and   
                  Joachim Frank   Visualization of Trna Movements on the
                                  \bionameEscherichia coli 70s Ribosome
                                  during the Elongation Cycle  . . . . . . 447
           William A. Prinz and   
                 Lara Grzyb and   
            Marten Veenhuis and   
            Jason A. Kahana and   
           Pamela A. Silver and   
                Tom A. Rapoport   Mutants Affecting the Structure of the
                                  Cortical Endoplasmic Reticulum in
                                  \bionameSaccharomyces cerevisiae . . . . 461
 A. Barbara Dirac-Svejstrup and   
              James Shorter and   
           M. Gerard Waters and   
                  Graham Warren   Phosphorylation of the
                                  Vesicle--Tethering Protein P115 by a
                                  Casein Kinase II-like Enzyme Is Required
                                  for Golgi Reassembly from Isolated
                                  Mitotic Fragments  . . . . . . . . . . . 475
   Carlo W. T. van Roermund and   
              Henk F. Tabak and   
       Marlene van den Berg and   
       Ronald J. A. Wanders and   
               Ewald H. Hettema   Pex11p Plays a Primary Role in
                                  Medium--Chain Fatty Acid Oxidation, a
                                  Process That Affects Peroxisome Number
                                  and Size in \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 489
          Gregory C. Rogers and   
              Kitty K. Chui and   
               Edwin W. Lee and   
           Karen P. Wedaman and   
             David J. Sharp and   
               Gina Holland and   
           Robert L. Morris and   
            Jonathan M. Scholey   A Kinesin--Related Protein, Krp$_{180}$,
                                  Positions Prometaphase Spindle Poles
                                  during Early Sea Urchin Embryonic Cell
                                  Division . . . . . . . . . . . . . . . . 499
         Natalie L. Catlett and   
              Jason E. Duex and   
               Fusheng Tang and   
                Lois S. Weisman   Two Distinct Regions in a Yeast
                                  Myosin--V Tail Domain Are Required for
                                  the Movement of Different Cargoes  . . . 513
              Justin Skoble and   
          Daniel A. Portnoy and   
               Matthew D. Welch   Three Regions within ActA Promote Arp2/3
                                  Complex-Mediated Actin Nucleation and
                                  \bionameListeria monocytogenes Motility  527
               Karen Oegema and   
         Matthew S. Savoian and   
       Timothy J. Mitchison and   
             Christine M. Field   Functional Analysis of a Human Homologue
                                  of the \bionameDrosophila Actin Binding
                                  Protein Anillin Suggests a Role in
                                  Cytokinesis  . . . . . . . . . . . . . . 539
                   K. Ojima and   
                  Z. X. Lin and   
                 M.-L. Bang and   
                 S. Holtzer and   
                 R. Matsuda and   
                  S. Labeit and   
              H. L. Sweeney and   
                     H. Holtzer   Distinct Families of Z--Line Targeting
                                  Modules in the Cooh--Terminal Region of
                                  Nebulin  . . . . . . . . . . . . . . . . 553
            Nicole K. Noren and   
               Betty P. Liu and   
             Keith Burridge and   
                  Bertolt Kreft   P120 Catenin Regulates the Actin
                                  Cytoskeleton via Rho Family Gtpases  . . 567
              Ingeborg Berg and   
         Barry V. L. Potter and   
              Georg W. Mayr and   
                Andreas H. Guse   Nicotinic Acid Adenine Dinucleotide
                                  Phosphate (Naadp$^+$) Is an Essential
                                  Regulator of T-Lymphocyte
                                  Ca$^{2+}$-Signaling  . . . . . . . . . . 581
             Todd W. Harris and   
             Erika Hartwieg and   
          H. Robert Horvitz and   
              Erik M. Jorgensen   Mutations in Synaptojanin Disrupt
                                  Synaptic Vesicle Recycling . . . . . . . 589
                    Yves Gaudin   Rabies Virus--Induced Membrane Fusion
                                  Pathway  . . . . . . . . . . . . . . . . 601
         Robert A. Screaton and   
              Luisa DeMarte and   
         Petr Dráber and   
           Clifford P. Stanners   The Specificity for the Differentiation
                                  Blocking Activity of Carcinoembryonic
                                  Antigen Resides in Its
                                  Glycophosphatidyl--Inositol Anchor . . . 613
       Jeffrey A. Greenwood and   
           Anne B. Theibert and   
         Glenn D. Prestwich and   
       Joanne E. Murphy-Ullrich   Restructuring of Focal Adhesion Plaques
                                  by Pi 3-Kinase . . . . . . . . . . . . . 627
             Mana M. Parast and   
                  Carol A. Otey   Characterization of Palladin, a Novel
                                  Protein Localized to Stress Fibers and
                                  Cell Adhesions . . . . . . . . . . . . . 643
                Steven Tait and   
           Frank Gunn-Moore and   
        J. Martin Collinson and   
              Jeffery Huang and   
         Catherine Lubetzki and   
            Liliana Pedraza and   
           Diane L. Sherman and   
            David R. Colman and   
                Peter J. Brophy   An Oligodendrocyte Cell Adhesion
                                  Molecule at the Site of Assembly of the
                                  Paranodal Axo--Glial Junction  . . . . . 657
            Barbara Gayraud and   
           Douglas R. Keene and   
              Lynn Y. Sakai and   
              Francesco Ramirez   New Insights into the Assembly of
                                  Extracellular Microfibrils from the
                                  Analysis of the Fibrillin 1 Mutation in
                                  the Tight skin Mouse . . . . . . . . . . 667
         Vladimir P. Efimov and   
               N. Ronald Morris   The Lis1-Related Nudf Protein of
                                  \bionameAspergillus nidulans Interacts
                                  with the Coiled-Coil Domain of the
                                  Nude/Ro11 Protein  . . . . . . . . . . . 681
            Hans-Georg Koch and   
           Matthias Müller   Dissecting the Translocase and Integrase
                                  Functions of the \bionameEscherichia
                                  coli Secyeg Translocon . . . . . . . . . 689

Journal of Cell Biology
Volume 150, Number 4, August, 2000

                    Anne Ridley   Rho Gtpases  . . . . . . . . . . . . . . 0
   Katja Sträßer and   
        Jochen Baßler and   
                        Ed Hurt   Binding of the Mex67p/Mtr2p Heterodimer
                                  to Fxfg, Glfg, and Fg Repeat
                                  Nucleoporins Is Essential for Nuclear
                                  mRNA Export  . . . . . . . . . . . . . . 695
                 Chi Y. Yun and   
                  Xiang-Dong Fu   Conserved Sr Protein Kinase Functions in
                                  Nuclear Import and Its Action Is
                                  Counteracted by Arginine Methylation in
                                  \bionameSaccharomyces cerevisiae . . . . 707
              Yuichiro Kida and   
            Masao Sakaguchi and   
           Mitsunori Fukuda and   
        Katsuhiko Mikoshiba and   
              Katsuyoshi Mihara   Membrane Topogenesis of a Type I
                                  Signal--Anchor Protein, Mouse
                                  Synaptotagmin Ii, on the Endoplasmic
                                  Reticulum  . . . . . . . . . . . . . . . 719
         Kimitoshi Nakamura and   
          Ella Bossy-Wetzel and   
             Kimberly Burns and   
              Marc P. Fadel and   
                 Mira Lozyk and   
            Ing Swie Goping and   
                Michal Opas and   
         R. Chris Bleackley and   
           Douglas R. Green and   
                 Marek Michalak   Changes in Endoplasmic Reticulum Luminal
                                  Environment Affect Cell Sensitivity to
                                  Apoptosis  . . . . . . . . . . . . . . . 731
         Graham C. Fletcher and   
                Luzheng Xue and   
      Shareta K. Passingham and   
             Aviva M. Tolkovsky   Death Commitment Point Is Advanced by
                                  Axotomy in Sympathetic Neurons . . . . . 741
                Liwen Jiang and   
         Thomas E. Phillips and   
            Sally W. Rogers and   
                 John C. Rogers   Biogenesis of the Protein Storage
                                  Vacuole Crystalloid  . . . . . . . . . . 755
         Jeffrey A. Spencer and   
              Susan Eliazer and   
           Robert L. Ilaria and   
        James A. Richardson and   
                  Eric N. Olson   Regulation of Microtubule Dynamics and
                                  Myogenic Differentiation by Murf, a
                                  Striated Muscle Ring--Finger Protein . . 771
                M. Glogauer and   
                 J. Hartwig and   
                     T. Stossel   Two Pathways through Cdc42 Couple the N
                                  -Formyl Receptor to Actin Nucleation in
                                  Permeabilized Human Neutrophils  . . . . 785
               Go Totsukawa and   
         Yoshihiko Yamakita and   
          Shigeko Yamashiro and   
        David J. Hartshorne and   
            Yasuharu Sasaki and   
                Fumio Matsumura   Distinct Roles of Rock (Rho--Kinase) and
                                  Mlck in Spatial Regulation of Mlc
                                  Phosphorylation for Assembly of Stress
                                  Fibers and Focal Adhesions in 3t3
                                  Fibroblasts  . . . . . . . . . . . . . . 797
      Josephine Clare Adams and   
      Martin Alexander Schwartz   Stimulation of Fascin Spikes by
                                  Thrombospondin-1 Is Mediated by the
                                  Gtpases Rac and Cdc42  . . . . . . . . . 807
        Douglas N. Robinson and   
               James A. Spudich   Dynacortin, a Genetic Link between
                                  Equatorial Contractility and Global
                                  Shape Control Discovered by Library
                                  Complementation of a
                                  \bionameDictyostelium discoideum
                                  Cytokinesis Mutant . . . . . . . . . . . 823
         Amanda J. Cochilla and   
         Joseph K. Angleson and   
                William J. Betz   Differential Regulation of
                                  Granule--to--Granule and
                                  Granule--to--Plasma Membrane Fusion
                                  during Secretion from Rat Pituitary
                                  Lactotrophs  . . . . . . . . . . . . . . 839
              Thomas Lecuit and   
                 Eric Wieschaus   Polarized Insertion of New Membrane from
                                  a Cytoplasmic Reservoir during Cleavage
                                  of the \bionameDrosophila Embryo . . . . 849
                  Yao Huang and   
                      Ji Li and   
              Yongjun Zhang and   
                    Chuanyue Wu   The Roles of Integrin--Linked Kinase in
                                  the Regulation of Myogenic
                                  Differentiation  . . . . . . . . . . . . 861
             Ayako Yamamoto and   
        Yoshihiro Hashimoto and   
              Kenjiro Kohri and   
               Etsuro Ogata and   
             Shige-aki Kato and   
                Kyoji Ikeda and   
               Makoto Nakanishi   Cyclin E as a Coactivator of the
                                  Androgen Receptor  . . . . . . . . . . . 873
      Vladimir I. Titorenko and   
         Richard A. Rachubinski   Peroxisomal Membrane Fusion Requires Two
                                  Aaa Family Atpases, Pex1p and Pex6p  . . 881
         Toshiyuki Nakagawa and   
                   Junying Yuan   Cross-Talk between Two Cysteine Protease
                                  Families . . . . . . . . . . . . . . . . 887
              Amy K. Wolven and   
            Lisa D. Belmont and   
          Nicole M. Mahoney and   
             Steven C. Almo and   
                David G. Drubin   In Vivo Importance of Actin Nucleotide
                                  Exchange Catalyzed by Profilin . . . . . 895
       Stefano Confalonieri and   
    Anna Elisabetta Salcini and   
               Claudia Puri and   
            Carlo Tacchetti and   
            Pier Paolo Di Fiore   Tyrosine Phosphorylation of Eps15 Is
                                  Required for Ligand--Regulated, but Not
                                  Constitutive, Endocytosis  . . . . . . . 905
            Melissa B. Wenk and   
             Kim S. Midwood and   
           Jean E. Schwarzbauer   Tenascin-C Suppresses Rho Activation . . 913
               Pauline Wong and   
         Emma Colucci-Guyon and   
            Kenzo Takahashi and   
               Changhong Gu and   
            Charles Babinet and   
             Pierre A. Coulombe   Introducing a Null Mutation in the Mouse
                                  K6$ \alpha $ and K6$ \beta $ Genes
                                  Reveals Their Essential Structural Role
                                  in the Oral Mucosa . . . . . . . . . . . 921
            Yosef Landesman and   
       Daniel A. Goodenough and   
                  David L. Paul   Gap Junctional Communication in the
                                  Early \bionameXenopus Embryo . . . . . . 929

Journal of Cell Biology
Volume 150, Number 5, September, 2000

            Britta Qualmann and   
         Michael M. Kessels and   
                 Regis B. Kelly   Molecular Links between Endocytosis and
                                  the Actin Cytoskeleton . . . . . . . . . 0
           Jonathan D. Wood and   
      Frederick C. Nucifora and   
                   Kui Duan and   
              Chuanyi Zhang and   
             Jianxiang Wang and   
                  Yujin Kim and   
         Gabriele Schilling and   
           Nicoletta Sacchi and   
             Johnson M. Liu and   
            Christopher A. Ross   Atrophin-1, the Dentato--Rubral and
                                  Pallido--Luysian Atrophy Gene Product,
                                  Interacts with Eto/Mtg8 in the Nuclear
                                  Matrix and Represses Transcription . . . 939
              Oliver Nayler and   
        Annette M. Hartmann and   
                   Stefan Stamm   The ER Repeat Protein Yt521-B Localizes
                                  to a Novel Subnuclear Compartment  . . . 949
Daniel Pérez-Mongiovi and   
          Clare Beckhelling and   
              Patrick Chang and   
        Christopher C. Ford and   
               Evelyn Houliston   Nuclei and Microtubule Asters Stimulate
                                  Maturation/M Phase Promoting Factor
                                  (Mpf) Activation in \bionameXenopus Eggs
                                  and Egg Cytoplasmic Extracts . . . . . . 963
            Tarun M. Kapoor and   
            Thomas U. Mayer and   
       Margaret L. Coughlin and   
           Timothy J. Mitchison   Probing Spindle Assembly Mechanisms with
                                  Monastrol, a Small Molecule Inhibitor of
                                  the Mitotic Kinesin, Eg5 . . . . . . . . 975
               Yosuke Takei and   
                Junlin Teng and   
             Akihiro Harada and   
              Nobutaka Hirokawa   Defects in Axonal Elongation and
                                  Neuronal Migration in Mice with
                                  Disrupted tau and map1b Genes  . . . . . 989
             Changsong Yang and   
              Minzhou Huang and   
              John DeBiasio and   
               Martin Pring and   
              Michael Joyce and   
               Hiroaki Miki and   
           Tadaomi Takenawa and   
               Sally H. Zigmond   Profilin Enhances Cdc42-Induced
                                  Nucleation of Actin Polymerization . . . 1001
             Eva M. Neuhaus and   
                Thierry Soldati   A Myosin I Is Involved in Membrane
                                  Recycling from Early Endosomes . . . . . 1013
           Oliver von Ahsen and   
           Christian Renken and   
                Guy Perkins and   
              Ruth M. Kluck and   
          Ella Bossy-Wetzel and   
             Donald D. Newmeyer   Preservation of Mitochondrial Structure
                                  and Function after Bid- or Bax-Mediated
                                  Cytochrome c Release . . . . . . . . . . 1027
     Josée N. Lavoie and   
          Claudia Champagne and   
       Marie-Claude Gingras and   
           Amélie Robert   Adenovirus E4 Open Reading Frame
                                  4--Induced Apoptosis Involves
                                  Dysregulation of Src Family Kinases  . . 1037
        Richard D. Minshall and   
     Chinnaswamy Tiruppathi and   
           Stephen M. Vogel and   
            Walter D. Niles and   
          Annette Gilchrist and   
              Heidi E. Hamm and   
                 Asrar B. Malik   Endothelial Cell--Surface Gp60 Activates
                                  Vesicle Formation and Trafficking via
                                  G$_i$ -Coupled Src Kinase Signaling
                                  Pathway  . . . . . . . . . . . . . . . . 1057
           Larry S. Sherman and   
             Tilat A. Rizvi and   
           Saikumar Karyala and   
                   Nancy Ratner   Cd44 Enhances Neuregulin Signaling by
                                  Schwann Cells  . . . . . . . . . . . . . 1071
              Joon Yung Lee and   
        Zhuqing Qu-Petersen and   
                Baohong Cao and   
             Shigemi Kimura and   
              Ron Jankowski and   
              James Cummins and   
               Arvydas Usas and   
              Charley Gates and   
               Paul Robbins and   
               Anton Wernig and   
                   Johnny Huard   Clonal Isolation of Muscle--Derived
                                  Cells Capable of Enhancing Muscle
                                  Regeneration and Bone Healing  . . . . . 1085
              Dong Min Shin and   
             Xiao-Song Zhao and   
              Weizhong Zeng and   
           Marina Mozhayeva and   
                 Shmuel Muallem   The Mammalian Sec6/8 Complex Interacts
                                  with Ca$^{2+}$ Signaling Complexes and
                                  Regulates Their Activity . . . . . . . . 1101
        Eduard B. Babiychuk and   
                Annette Draeger   Annexins in Cell Membrane Dynamics . . . 1113
           Radhika C. Desai and   
                 Bimal Vyas and   
          Cynthia A. Earles and   
          J. Troy Littleton and   
       Judith A. Kowalchyck and   
        Thomas F. J. Martin and   
                  E. R. Chapman   The C2b Domain of Synaptotagmin Is a
                                  Ca$^{2+}$ --Sensing Module Essential for
                                  Exocytosis . . . . . . . . . . . . . . . 1125
                Sanja Sever and   
                Hanna Damke and   
               Sandra L. Schmid   Dynamin: GTP Controls the Formation of
                                  Constricted Coated Pits, the Rate
                                  Limiting Step in Clathrin-Mediated
                                  Endocytosis  . . . . . . . . . . . . . . 1137
           Srikala Raghavan and   
            Christoph Bauer and   
             Gina Mundschau and   
                 Qingqin Li and   
                   Elaine Fuchs   Conditional Ablation of $ \beta $1
                                  Integrin in Skin . . . . . . . . . . . . 1149
          Kouichi Tachibana and   
         Hiroyuki Nakanishi and   
               Kenji Mandai and   
                 Kumi Ozaki and   
               Wataru Ikeda and   
          Yasunori Yamamoto and   
            Akira Nagafuchi and   
          Shoichiro Tsukita and   
                  Yoshimi Takai   Two Cell Adhesion Molecules, Nectin and
                                  Cadherin, Interact through Their
                                  Cytoplasmic Domain--Associated Proteins  1161
        Atsuko Ishizuya-Oka and   
                    Qing Li and   
             Tosikazu Amano and   
         Sashko Damjanovski and   
               Shuichi Ueda and   
                     Yun-Bo Shi   Requirement for Matrix Metalloproteinase
                                  Stromelysin-3 in Cell Migration and
                                  Apoptosis during Tissue Remodeling in
                                  \bionameXenopus laevis . . . . . . . . . 1177
      Theodore P. Rasmussen and   
       Mary-Ann Mastrangelo and   
                  Amir Eden and   
            John R. Pehrson and   
                Rudolf Jaenisch   Dynamic Relocalization of Histone
                                  Macroh2a1 from Centrosomes to Inactive X
                                  Chromosomes during X Inactivation  . . . 1189
María Victoria González and   
     Benilde Jiménez and   
   María T. Berciano and   
José Manuel González-Sancho and   
              Carme Caelles and   
             Miguel Lafarga and   
           Alberto Muñoz   Glucocorticoids Antagonize Ap-1 by
                                  Inhibiting the
                                  Activation/Phosphorylation of Jnk
                                  without Affecting Its Subcellular
                                  Distribution . . . . . . . . . . . . . . 1199
           Inna N. Rybakova and   
     Jitandrakumar R. Patel and   
               James M. Ervasti   The Dystrophin Complex Forms a
                                  Mechanically Strong Link between the
                                  Sarcolemma and Costameric Actin  . . . . 1209
            Patricia Murray and   
                    David Edgar   Regulation of Programmed Cell Death by
                                  Basement Membranes in Embryonic
                                  Development  . . . . . . . . . . . . . . 1215

Journal of Cell Biology
Volume 150, Number 6, September, 2000

               Sally H. Zigmond   How Wasp Regulates Actin Polymerization  0
               Louise P. Cramer   Myosin VI  . . . . . . . . . . . . . . . ??
       Leocadia V. Paliulis and   
               R. Bruce Nicklas   The Reduction of Chromosome Number in
                                  Meiosis Is Determined by Properties
                                  Built into the Chromosomes . . . . . . . 1223
               B. J. Howell and   
              D. B. Hoffman and   
                    G. Fang and   
               A. W. Murray and   
                   E. D. Salmon   Visualization of Mad2 Dynamics at
                                  Kinetochores, along Spindle Fibers, and
                                  at Spindle Poles in Living Cells . . . . 1233
             Rikke L. Steen and   
          Sandra B. Martins and   
       Kjetil Taskén and   
                Philippe Collas   Recruitment of Protein Phosphatase 1 to
                                  the Nuclear Envelope by a--Kinase
                                  Anchoring Protein Akap149 Is a
                                  Prerequisite for Nuclear Lamina Assembly 1251
                 Lelio Orci and   
           Myl\`ene Amherdt and   
         Mariella Ravazzola and   
             Alain Perrelet and   
               James E. Rothman   Exclusion of Golgi Residents from
                                  Transport Vesicles Budding from Golgi
                                  Cisternae in Intact Cells  . . . . . . . 1263
            Alison J. Davis and   
           Naresh B. Sepuri and   
               Jason Holder and   
          Arthur E. Johnson and   
               Robert E. Jensen   Two Intermembrane Space Tim Complexes
                                  Interact with Different Domains of
                                  Tim23p during Its Import into
                                  Mitochondria . . . . . . . . . . . . . . 1271
            Derek J. Milner and   
          Manolis Mavroidis and   
             Noah Weisleder and   
             Yassemi Capetanaki   Desmin Cytoskeleton Linked to Muscle
                                  Mitochondrial Distribution and
                                  Respiratory Function . . . . . . . . . . 1283
              Rajat Rohatgi and   
           Hsin-yi Henry Ho and   
              Marc W. Kirschner   Mechanism of N--Wasp Activation by Cdc42
                                  and Phosphatidylinositol
                                  4,5-Bisphosphate . . . . . . . . . . . . 1299
             Henry N. Higgs and   
              Thomas D. Pollard   Activation by Cdc42 and Pip$_2$ of
                                  Wiskott--Aldrich Syndrome Protein (Wasp)
                                  Stimulates Actin Nucleation by Arp2/3
                                  Complex  . . . . . . . . . . . . . . . . 1311
              Zhengshan Dai and   
                Xiaoyan Luo and   
                 Hongbo Xie and   
               H. Benjamin Peng   The Actin-Driven Movement and Formation
                                  of Acetylcholine Receptor Clusters . . . 1321
              Ritsuko Fujii and   
           Susumu Yamashita and   
              Masahiko Hibi and   
                  Toshio Hirano   Asymmetric p38 Activation in Zebrafish   1335
László Homolya and   
        Thomas H. Steinberg and   
             Richard C. Boucher   Cell to Cell Communication in Response
                                  to Mechanical Stress via Bilateral
                                  Release of ATP and Utp in Polarized
                                  Epithelia  . . . . . . . . . . . . . . . 1349
             Andreas Wodarz and   
            Andreas Ramrath and   
            Alexandra Grimm and   
                Elisabeth Knust   Drosophila Atypical Protein Kinase C
                                  Associates with Bazooka and Controls
                                  Polarity of Epithelia and Neuroblasts    1361
               Martin Sachs and   
           Henning Brohmann and   
            Dietmar Zechner and   
         Thomas Müller and   
     Jörg Hülsken and   
             Ingrid Walther and   
               Ute Schaeper and   
          Carmen Birchmeier and   
              Walter Birchmeier   Essential Role of Gab1 for Signaling by
                                  the C--Met Receptor in Vivo  . . . . . . 1375
            Marvin E. Adams and   
              Neal Kramarcy and   
            Stuart P. Krall and   
            Susana G. Rossi and   
         Richard L. Rotundo and   
             Robert Sealock and   
            Stanley C. Froehner   Absence of $ \alpha $-Syntrophin Leads
                                  to Structurally Aberrant Neuromuscular
                                  Synapses Deficient in Utrophin . . . . . 1385
        Gregory E. Crawford and   
           John A. Faulkner and   
        Rachelle H. Crosbie and   
          Kevin P. Campbell and   
        Stanley C. Froehner and   
         Jeffrey S. Chamberlain   Assembly of the Dystrophin--Associated
                                  Protein Complex Does Not Require the
                                  Dystrophin Cooh--Terminal Domain . . . . 1399
              Hong-Sheng Li and   
                  Craig Montell   TRP and the PDZ Protein, Inad, Form the
                                  Core Complex Required for Retention of
                                  the Signalplex in \bionameDrosophila
                                  Photoreceptor Cells  . . . . . . . . . . 1411
                    Jing Du and   
                Linyin Feng and   
                  Feng Yang and   
                         Bai Lu   Activity- and Ca$^{2+}$-Dependent
                                  Modulation of Surface Expression of
                                  Brain-Derived Neurotrophic Factor
                                  Receptors in Hippocampal Neurons . . . . 1423
             Alla F. Fomina and   
      Christopher M. Fanger and   
             J. Ashot Kozak and   
             Michael D. Cahalan   Single Channel Properties and Regulated
                                  Expression of Ca$^{2+}$
                                  Release--Activated Ca$^{2+}$ (Crac)
                                  Channels in Human T Cells  . . . . . . . 1435
           Vincenzo Cirulli and   
         Gillian M. Beattie and   
               George Klier and   
              Mark Ellisman and   
            Camillo Ricordi and   
              Vito Quaranta and   
           Francine Frasier and   
          Jennifer K. Ishii and   
              Alberto Hayek and   
              Daniel R. Salomon   Expression and Function of $ \alpha_v
                                  \beta_3 $ and $ \alpha_v \beta_5 $
                                  Integrins in the Developing Pancreas . . 1445
            Richard L. Roll and   
           Eve Marie Bauman and   
            Joel S. Bennett and   
              Charles S. Abrams   Phosphorylated Pleckstrin Induces Cell
                                  Spreading via an Integrin--Dependent
                                  Pathway  . . . . . . . . . . . . . . . . 1461
               Thomas Plath and   
           Katharina Detjen and   
             Martina Welzel and   
        Zofia von Marschall and   
               Derek Murphy and   
           Michael Schirner and   
         Bertram Wiedenmann and   
                Stefan Rosewicz   A Novel Function for the Tumor
                                  Suppressor p16$^{\rm INK4a}$ . . . . . . 1467
     Gaëlle Le'Negrate and   
                 Eric Selva and   
           Patrick Auberger and   
              Bernard Rossi and   
                    Paul Hofman   Sustained Polymorphonuclear Leukocyte
                                  Transmigration Induces Apoptosis in T84
                                  Intestinal Epithelial Cells  . . . . . . 1479
               Hui-Jun Wang and   
               Ginette Guay and   
                Liviu Pogan and   
          Remy Sauvé and   
                   Ivan R. Nabi   Calcium Regulates the Association
                                  between Mitochondria and a Smooth
                                  Subdomain of the Endoplasmic Reticulum   1489
                Naoko Nagai and   
          Masanori Hosokawa and   
         Shigeyoshi Itohara and   
              Eijiro Adachi and   
       Takatoshi Matsushita and   
            Nobuko Hosokawa and   
                Kazuhiro Nagata   Embryonic Lethality of Molecular
                                  Chaperone Hsp47 Knockout Mice Is
                                  Associated with Defects in Collagen
                                  Biosynthesis . . . . . . . . . . . . . . 1499
            Yoshiaki Kamada and   
           Tomoko Funakoshi and   
          Takahiro Shintani and   
              Kazuya Nagano and   
              Mariko Ohsumi and   
               Yoshinori Ohsumi   Tor-Mediated Induction of Autophagy via
                                  an Apg1 Protein Kinase Complex . . . . . 1507


Journal of Cell Biology
Volume 151, Number 1, October, 2000

     Christopher M. Brennan and   
       Imed-Eddine Gallouzi and   
                 Joan A. Steitz   Protein Ligands to Hur Modulate Its
                                  Interaction with Target Mrnas in Vivo    1
             Heidi Browning and   
          Jacqueline Hayles and   
                  Juan Mata and   
             Lauren Aveline and   
                 Paul Nurse and   
            J. Richard McIntosh   Tea2p Is a Kinesin-like Protein Required
                                  to Generate Polarized Growth in Fission
                                  Yeast  . . . . . . . . . . . . . . . . . 15
              Scott A. Weed and   
         Andrei V. Karginov and   
         Dorothy A. Schafer and   
           Alissa M. Weaver and   
           Andrew W. Kinley and   
             John A. Cooper and   
              J. Thomas Parsons   Cortactin Localization to Sites of Actin
                                  Assembly in \bionameLamellipodia
                                  Requires Interactions with F-Actin and
                                  the Arp2/3 Complex . . . . . . . . . . . 29
          Robert W. Burgess and   
         William C. Skarnes and   
                Joshua R. Sanes   Agrin Isoforms with Distinct Amino
                                  Termini  . . . . . . . . . . . . . . . . 41
            Iryna M. Ethell and   
            Kazuki Hagihara and   
             Yoshiaki Miura and   
             Fumitoshi Irie and   
                   Yu Yamaguchi   Synbindin, a Novel Syndecan-2--Binding
                                  Protein in Neuronal Dendritic Spines . . 53
         Richard G. Gardner and   
     Gwendolyn M. Swarbrick and   
             Nathan W. Bays and   
          Stephen R. Cronin and   
           Sharon Wilhovsky and   
               Linda Seelig and   
              Christine Kim and   
            Randolph Y. Hampton   Endoplasmic Reticulum Degradation
                                  Requires Lumen to Cytosol Signaling  . . 69
               Olga Krylova and   
        Marcus J. Messenger and   
            Patricia C. Salinas   Dishevelled-1 Regulates Microtubule
                                  Stability  . . . . . . . . . . . . . . . 83
      Edgar Trelles-Sticken and   
         Michael E. Dresser and   
                Harry Scherthan   Meiotic Telomere Protein Ndj1p Is
                                  Required for Meiosis--Specific Telomere
                                  Distribution, Bouquet Formation and
                                  Efficient Homologue Pairing  . . . . . . 95
        Kimberly S. Straley and   
                Samuel A. Green   Rapid Transport of Internalized
                                  P--Selectin to Late Endosomes and the
                                  Tgn  . . . . . . . . . . . . . . . . . . 107
                   Syed Haq and   
          Gabriel Choukroun and   
              Zhao Bin Kang and   
               Hardeep Ranu and   
             Takashi Matsui and   
         Anthony Rosenzweig and   
       Jeffrey D. Molkentin and   
    Alessandro Alessandrini and   
             James Woodgett and   
               Roger Hajjar and   
             Ashour Michael and   
                   Thomas Force   Glycogen Synthase Kinase-3$ \beta $ Is a
                                  Negative Regulator of Cardiomyocyte
                                  Hypertrophy  . . . . . . . . . . . . . . 117
                Hong-Guo Yu and   
                  R. Kelly Dawe   Functional Redundancy in the Maize
                                  Meiotic Kinetochore  . . . . . . . . . . 131
              Mikael Simons and   
      Eva-Maria Krämer and   
           Christoph Thiele and   
            Wilhelm Stoffel and   
             Jacqueline Trotter   Assembly of Myelin by Association of
                                  Proteolipid Protein with Cholesterol-
                                  and Galactosylceramide--Rich Membrane
                                  Domains  . . . . . . . . . . . . . . . . 143
              Eric L. Reese and   
                  Leah T. Haimo   Dynein, Dynactin, and Kinesin II's
                                  Interaction with Microtubules Is
                                  Regulated during Bidirectional Organelle
                                  Transport  . . . . . . . . . . . . . . . 155
              Kathrin Plath and   
                Tom A. Rapoport   Spontaneous Release of Cytosolic
                                  Proteins from Posttranslational
                                  Substrates before Their Transport into
                                  the Endoplasmic Reticulum  . . . . . . . 167
         Eustratios Bananis and   
             John W. Murray and   
        Richard J. Stockert and   
                Peter Satir and   
               Allan W. Wolkoff   Microtubule and Motor--Dependent
                                  Endocytic Vesicle Sorting in Vitro . . . 179
            Mark A. McNiven and   
                  Leung Kim and   
          Eugene W. Krueger and   
              James D. Orth and   
                   Hong Cao and   
                   Tai Wai Wong   Regulated Interactions between Dynamin
                                  and the Actin--Binding Protein Cortactin
                                  Modulate Cell Shape  . . . . . . . . . . 187

Journal of Cell Biology
Volume 151, Number 2, October, 2000

     Alexander M. van der Bliek   A Mitochondrial Division Apparatus Takes
                                  Shape  . . . . . . . . . . . . . . . . . 0
              Peter M. Steinert   The Complexity and Redundancy of
                                  Epithelial Barrier Function  . . . . . . ??
             Robert W. Doms and   
                  John P. Moore   HIV-1 Membrane Fusion  . . . . . . . . . ??
              Thomas Harder and   
                    Marina Kuhn   Selective Accumulation of
                                  Raft--Associated Membrane Protein Lat in
                                  T Cell Receptor Signaling Assemblies . . 199
               Sho Tokumaru and   
        Shigeki Higashiyama and   
               Takeshi Endo and   
         Takatoshi Nakagawa and   
        Jun-ichiro Miyagawa and   
           Katsumi Yamamori and   
           Yasushi Hanakawa and   
             Hiroshi Ohmoto and   
          Kohichiro Yoshino and   
             Yuji Shirakata and   
             Yuji Matsuzawa and   
             Koji Hashimoto and   
              Naoyuki Taniguchi   Ectodomain Shedding of Epidermal Growth
                                  Factor Receptor Ligands Is Required for
                                  Keratinocyte Migration in Cutaneous
                                  Wound Healing  . . . . . . . . . . . . . 209
                Manuel Koch and   
           Julie R. Murrell and   
             Dale D. Hunter and   
            Pamela F. Olson and   
                William Jin and   
           Douglas R. Keene and   
         William J. Brunken and   
             Robert E. Burgeson   A Novel Member of the Netrin Family, $
                                  \beta $-Netrin, Shares Homology with the
                                  $ \beta $ Chain of Laminin . . . . . . . 221
    Peter F. M. van der Ven and   
          Sebastian Wiesner and   
          Paula Salmikangas and   
            Daniel Auerbach and   
               Mirko Himmel and   
               Stefan Kempa and   
         Katrin Hayeß and   
             Dirk Pacholsky and   
              Anu Taivainen and   
         Rolf Schröder and   
         Olli Carpén and   
           Dieter O. Fürst   Indications for a Novel Muscular
                                  Dystrophy Pathway  . . . . . . . . . . . 235
Concepción Jiménez and   
      Rosario Armas Portela and   
              Mario Mellado and   
Jose Miguel Rodríguez-Frade and   
               John Collard and   
            Antonio Serrano and   
   Carlos Martínez-A and   
                Jesus Avila and   
                 Ana C. Carrera   Role of the Pi3k Regulatory Subunit in
                                  the Control of Actin Organization and
                                  Cell Migration . . . . . . . . . . . . . 249
         Takayoshi Kirisako and   
         Yoshinobu Ichimura and   
              Hisashi Okada and   
              Yukiko Kabeya and   
           Noboru Mizushima and   
          Tamotsu Yoshimori and   
              Mariko Ohsumi and   
            Toshifumi Takao and   
               Takeshi Noda and   
               Yoshinori Ohsumi   The Reversible Modification Regulates
                                  the Membrane-Binding State of Apg8/Aut7
                                  Essential for Autophagy and the
                                  Cytoplasm to Vacuole Targeting Pathway   263
             Sachiko Kanaji and   
               Jun Iwahashi and   
              Yuichiro Kida and   
            Masao Sakaguchi and   
              Katsuyoshi Mihara   Characterization of the Signal That
                                  Directs Tom20 to the Mitochondrial Outer
                                  Membrane . . . . . . . . . . . . . . . . 277
                   Wei Wang and   
             Michael Sacher and   
             Susan Ferro-Novick   Trapp Stimulates Guanine Nucleotide
                                  Exchange on Ypt1p  . . . . . . . . . . . 289
         Steven F. Nothwehr and   
                 Seon-Ah Ha and   
                  Paul Bruinsma   Sorting of Yeast Membrane Proteins into
                                  an Endosome-to-Golgi Pathway Involves
                                  Direct Interaction of Their Cytosolic
                                  Domains with Vps35p  . . . . . . . . . . 297
            Marilena Marzia and   
            Natalie A. Sims and   
               Susanne Voit and   
          Silvia Migliaccio and   
               Anna Taranta and   
          Silvia Bernardini and   
          Tullio Faraggiana and   
           Toshiyuki Yoneda and   
           Gregory R. Mundy and   
           Brendan F. Boyce and   
               Roland Baron and   
                      Anna Teti   Decreased C--Src Expression Enhances
                                  Osteoblast Differentiation and Bone
                                  Formation  . . . . . . . . . . . . . . . 311
            Cynthia M. Lane and   
                Ian Cushman and   
             Mary Shannon Moore   Selective Disruption of Nuclear Import
                                  by a Functional Mutant Nuclear Transport
                                  Carrier  . . . . . . . . . . . . . . . . 321
               Peter Fekkes and   
           Kelly A. Shepard and   
               Michael P. Yaffe   Gag3p, an Outer Membrane Protein
                                  Required for Fission of Mitochondrial
                                  Tubules  . . . . . . . . . . . . . . . . 333
              Edith D. Wong and   
         Jennifer A. Wagner and   
          Steven W. Gorsich and   
       J. Michael McCaffery and   
              Janet M. Shaw and   
                   Jodi Nunnari   The Dynamin--Related Gtpase, Mgm1p, Is
                                  an Intermembrane Space Protein Required
                                  for Maintenance of Fusion Competent
                                  Mitochondria . . . . . . . . . . . . . . 341
               Quinton Tieu and   
                   Jodi Nunnari   Mdv1p Is a Wd Repeat Protein That
                                  Interacts with the Dynamin--Related
                                  Gtpase, Dnm1p, to Trigger Mitochondrial
                                  Division . . . . . . . . . . . . . . . . 353
                A. D. Mozdy and   
            J. M. McCaffery and   
                     J. M. Shaw   Dnm1p GTPase-Mediated Mitochondrial
                                  Fission Is a Multi-Step Process
                                  Requiring the Novel Integral Membrane
                                  Component Fis1p  . . . . . . . . . . . . 367
             Philippe Djian and   
               Karen Easley and   
                   Howard Green   Targeted Ablation of the Murine
                                  Involucrin Gene  . . . . . . . . . . . . 381
              Peter J. Koch and   
        Pierre A. de Viragh and   
          Elisabeth Scharer and   
             Donnie Bundman and   
           Mary Ann Longley and   
          Jackie Bickenbach and   
           Yasuhiro Kawachi and   
               Yasushi Suga and   
               Zhijian Zhou and   
               Marcel Huber and   
                Daniel Hohl and   
            Tonja Kartasova and   
              Michal Jarnik and   
         Alasdair C. Steven and   
                 Dennis R. Roop   Lessons from Loricrin--Deficient Mice    389
               Yasushi Suga and   
              Michal Jarnik and   
              Paul S. Attar and   
            Mary A. Longley and   
             Donnie Bundman and   
         Alasdair C. Steven and   
              Peter J. Koch and   
                 Dennis R. Roop   Transgenic Mice Expressing a Mutant Form
                                  of Loricrin Reveal the Molecular Basis
                                  of the Skin Diseases, Vohwinkel Syndrome
                                  and Progressive Symmetric
                                  Erythrokeratoderma . . . . . . . . . . . 401
        Grigory B. Melikyan and   
         Ruben M. Markosyan and   
               Hila Hemmati and   
          Mary K. Delmedico and   
          Dennis M. Lambert and   
               Fredric S. Cohen   Evidence That the Transition of HIV-1
                                  Gp41 into a Six--Helix Bundle, Not the
                                  Bundle Configuration, Induces Membrane
                                  Fusion . . . . . . . . . . . . . . . . . 413
          R. Todd Armstrong and   
            Anna S. Kushnir and   
                Judith M. White   The Transmembrane Domain of Influenza
                                  Hemagglutinin Exhibits a Stringent
                                  Length Requirement to Support the
                                  Hemifusion to Fusion Transition  . . . . 425
                 Eric Grote and   
            Chavela M. Carr and   
                Peter J. Novick   Ordering the Final Events in Yeast
                                  Exocytosis . . . . . . . . . . . . . . . 439
                 Eric Grote and   
                Misuzu Baba and   
           Yoshinori Ohsumi and   
                Peter J. Novick   Geranylgeranylated Snares Are Dominant
                                  Inhibitors of Membrane Fusion  . . . . . 453
        Bernhard E. Flucher and   
            Nicole Kasielke and   
                Manfred Grabner   The Triad Targeting Signal of the
                                  Skeletal Muscle Calcium Channel Is
                                  Localized in the Cooh Terminus of the $
                                  \alpha $$_{1S}$ Subunit  . . . . . . . . 467

Journal of Cell Biology
Volume 151, Number 3, October, 2000

               Honglin Zhou and   
                Xin-Ming Li and   
              Judy Meinkoth and   
             Randall N. Pittman   Akt Regulates Cell Survival and
                                  Apoptosis at a Postmitochondrial Level   483
         Florence A. Scholl and   
        Patricia McLoughlin and   
            Elisabeth Ehler and   
          Carla de Giovanni and   
           Beat W. Schäfer   Dral Is a P53-Responsive Gene Whose Four
                                  and a Half Lim Domain Protein Product
                                  Induces Apoptosis  . . . . . . . . . . . 495
        Britta Brügger and   
             Roger Sandhoff and   
          Sabine Wegehingel and   
               Karin Gorgas and   
           Jörg Malsam and   
             J. Bernd Helms and   
        Wolf-Dieter Lehmann and   
              Walter Nickel and   
               Felix T. Wieland   Evidence for Segregation of
                                  Sphingomyelin and Cholesterol during
                                  Formation of Copi--Coated Vesicles . . . 507
         Oliver Müller and   
              Tanja Sattler and   
  Matthias Flötenmeyer and   
              Heinz Schwarz and   
            Helmut Plattner and   
                  Andreas Mayer   Autophagic Tubes . . . . . . . . . . . . 519
              Tanja Sattler and   
                  Andreas Mayer   Cell-Free Reconstitution of
                                  Microautophagic Vacuole Invagination and
                                  Vesicle Formation  . . . . . . . . . . . 529
      M. Alejandro Barbieri and   
         Richard L. Roberts and   
            Aysel Gumusboga and   
           Hilary Highfield and   
   Carmen Alvarez-Dominguez and   
                 Alan Wells and   
                Philip D. Stahl   Epidermal Growth Factor and Membrane
                                  Trafficking  . . . . . . . . . . . . . . 539
          Andrew E. Wurmser and   
               Trey K. Sato and   
                   Scott D. Emr   New Component of the Vacuolar Class
                                  C--Vps Complex Couples Nucleotide
                                  Exchange on the Ypt7 Gtpase to
                                  Snare--Dependent Docking and Fusion  . . 551
            Yoshitaka Tamai and   
            Tomo-o Ishikawa and   
       Michael R. Bösl and   
              Masahiko Mori and   
              Masami Nozaki and   
    Heléne Baribault and   
           Robert G. Oshima and   
               Makoto M. Taketo   Cytokeratins 8 and 19 in the Mouse
                                  Placental Development  . . . . . . . . . 563
         Teresa DiColandrea and   
          Tadashi Karashima and   
 Arto Määttä and   
                  Fiona M. Watt   Subcellular Distribution of Envoplakin
                                  and Periplakin . . . . . . . . . . . . . 573
           Michael W. Black and   
              Hugh R. B. Pelham   A Selective Transport Route from Golgi
                                  to Late Endosomes That Requires the
                                  Yeast Gga Proteins . . . . . . . . . . . 587
               Erik Nielsen and   
      Savvas Christoforidis and   
Sandrine Uttenweiler-Joseph and   
           Marta Miaczynska and   
         Frederique Dewitte and   
              Matthias Wilm and   
            Bernard Hoflack and   
                  Marino Zerial   Rabenosyn-5, a Novel Rab5 Effector, Is
                                  Complexed with Hvps45 and Recruited to
                                  Endosomes through a Fyve Finger Domain   601
            Theresa Hartman and   
              Kristen Stead and   
           Douglas Koshland and   
                 Vincent Guacci   Pds5p Is an Essential Chromosomal
                                  Protein Required for Both Sister
                                  Chromatid Cohesion and Condensation in
                                  \bionameSaccharomyces cerevisiae . . . . 613
          Trevor R. Jackson and   
            Fraser D. Brown and   
              Zhongzhen Nie and   
               Koichi Miura and   
             Letizia Foroni and   
                Jianlan Sun and   
              Victor W. Hsu and   
         Julie G. Donaldson and   
               Paul A. Randazzo   Acaps Are Arf6 Gtpase--Activating
                                  Proteins That Function in the Cell
                                  Periphery  . . . . . . . . . . . . . . . 627
           Cristina Machado and   
              Deborah J. Andrew   D-Titin  . . . . . . . . . . . . . . . . 639
               Sabine Snaar and   
          Karien Wiesmeijer and   
          Aart G. Jochemsen and   
              Hans J. Tanke and   
               Roeland W. Dirks   Mutational Analysis of Fibrillarin and
                                  Its Mobility in Living Human Cells . . . 653
            Shannon E. Dunn and   
                Eva R. Chin and   
                Robin N. Michel   Matching of Calcineurin Activity to
                                  Upstream Effectors Is Critical for
                                  Skeletal Muscle Fiber Growth . . . . . . 663
             Karsten Mahnke and   
                   Ming Guo and   
                   Sena Lee and   
           Homero Sepulveda and   
              Suzy L. Swain and   
         Michel Nussenzweig and   
              Ralph M. Steinman   The Dendritic Cell Receptor for
                                  Endocytosis, Dec-205, Can Recycle and
                                  Enhance Antigen Presentation via Major
                                  Histocompatibility Complex Class
                                  II--Positive Lysosomal Compartments  . . 673
       Katarzyna Bialkowska and   
           Sucheta Kulkarni and   
                Xiaoping Du and   
             Darrel E. Goll and   
           Takaomi C. Saido and   
                 Joan E. B. Fox   Evidence That $ \beta $3
                                  Integrin--Induced Rac Activation
                                  Involves the Calpain--Dependent
                                  Formation of Integrin Clusters That Are
                                  Distinct from the Focal Complexes and
                                  Focal Adhesions That Form as Rac and
                                  Rhoa Become Active . . . . . . . . . . . 685
        Angela Poperechnaya and   
             Olga Varlamova and   
                 Pei-ju Lin and   
             James T. Stull and   
               Anne R. Bresnick   Localization and Activity of Myosin
                                  Light Chain Kinase Isoforms during the
                                  Cell Cycle . . . . . . . . . . . . . . . 697
          Gregory J. Pazour and   
         Bethany L. Dickert and   
              Yvonne Vucica and   
            E. Scott Seeley and   
          Joel L. Rosenbaum and   
           George B. Witman and   
                Douglas G. Cole   Chlamydomonas IFT 88 and Its Mouse
                                  Homologue, Polycystic Kidney Disease
                                  Gene Tg 737, Are Required for Assembly
                                  of Cilia and Flagella  . . . . . . . . . 709
          Maxwell G. Heiman and   
                   Peter Walter   Prm1p, a Pheromone--Regulated
                                  Multispanning Membrane Protein,
                                  Facilitates Plasma Membrane Fusion
                                  during Yeast Mating  . . . . . . . . . . 719
                 Linyi Chen and   
              Nicholas G. Davis   Recycling of the Yeast a -Factor
                                  Receptor . . . . . . . . . . . . . . . . 731

Journal of Cell Biology
Volume 151, Number 4, November, 2000

             Helmut Krämer   The Ups and Downs of Life in an
                                  Epithelium . . . . . . . . . . . . . . . 0
           Geoffrey I. McFadden   Skeletons in the Closet  . . . . . . . . ??
           Jennifer M. King and   
                Tom S. Hays and   
               R. Bruce Nicklas   Dynein Is a Transient Kinetochore
                                  Component Whose Binding Is Regulated by
                                  Microtubule Attachment, Not Tension  . . 739
             Izabela Sumara and   
        Elisabeth Vorlaufer and   
         Christian Gieffers and   
            Beate H. Peters and   
             Jan-Michael Peters   Characterization of Vertebrate Cohesin
                                  Complexes and Their Regulation in
                                  Prophase . . . . . . . . . . . . . . . . 749
               Mark R. Frey and   
          Jennifer A. Clark and   
             Olga Leontieva and   
           Joshua M. Uronis and   
            Adrian R. Black and   
              Jennifer D. Black   Protein Kinase C Signaling Mediates a
                                  Program of Cell Cycle Withdrawal in the
                                  Intestinal Epithelium  . . . . . . . . . 763
               Yoichi Ezura and   
         Shukti Chakravarti and   
          Åke Oldberg and   
            Inna Chervoneva and   
                  David E. Birk   Differential Expression of Lumican and
                                  Fibromodulin Regulate Collagen
                                  Fibrillogenesis in Developing Mouse
                                  Tendons  . . . . . . . . . . . . . . . . 779
                Wei-Lih Lee and   
        Magdalena Bezanilla and   
              Thomas D. Pollard   Fission Yeast Myosin-I, Myo1p,
                                  Stimulates Actin Assembly by Arp2/3
                                  Complex and Shares Functions with Wasp   789
        Aino Paasinen-Sohns and   
              Mari Kielosto and   
Essi Kääriäinen and   
             Terho Eloranta and   
                 Aire Laine and   
         Olli A. Jänne and   
          Michael J. Birrer and   
         Erkki Hölttä   C-Jun Activation--Dependent Tumorigenic
                                  Transformation Induced Paradoxically by
                                  Overexpression or Block of S
                                  -Adenosylmethionine Decarboxylase  . . . 801
             Gary A. Wayman and   
         Melinda J. Walters and   
           Kathryn Kolibaba and   
        Thomas R. Soderling and   
               Jan L. Christian   CAM Kinase IV Regulates Lineage
                                  Commitment and Survival of Erythroid
                                  Progenitors in a Non-Cell-Autonomous
                                  Manner . . . . . . . . . . . . . . . . . 811
          Erika S. Wittchen and   
              Julie Haskins and   
             Bruce R. Stevenson   Exogenous Expression of the
                                  Amino--Terminal Half of the Tight
                                  Junction Protein Zo-3 Perturbs
                                  Junctional Complex Assembly  . . . . . . 825
             Thibault Mayor and   
       York-Dieter Stierhof and   
              Kayoko Tanaka and   
              Andrew M. Fry and   
                  Erich A. Nigg   The Centrosomal Protein C--Nap1 Is
                                  Required for Cell Cycle--Regulated
                                  Centrosome Cohesion  . . . . . . . . . . 837
                Alex L. Mah and   
               George Perry and   
              Mark A. Smith and   
             Mervyn J. Monteiro   Identification of Ubiquilin, a Novel
                                  Presenilin Interactor That Increases
                                  Presenilin Protein Accumulation  . . . . 847
              Arash Komeili and   
           Karen P. Wedaman and   
             Erin K. O'Shea and   
                     Ted Powers   Mechanism of Metabolic Control . . . . . 863
          Michael T. Engsig and   
              Qing-Jun Chen and   
              Thiennu H. Vu and   
      Anne-Cecilie Pedersen and   
           Bente Therkidsen and   
               Leif R. Lund and   
              Kim Henriksen and   
             Thomas Lenhard and   
             Niels T. Foged and   
                  Zena Werb and   
     Jean-Marie Delaissé   Matrix Metalloproteinase 9 and Vascular
                                  Endothelial Growth Factor Are Essential
                                  for Osteoclast Recruitment into
                                  Developing Long Bones  . . . . . . . . . 879
             Guy Tanentzapf and   
            Christian Smith and   
               Jane McGlade and   
                  Ulrich Tepass   Apical, Lateral, and Basal Polarization
                                  Cues Contribute to the Development of
                                  the Follicular Epithelium during
                                  \bionameDrosophila Oogenesis . . . . . . 891
             John C. Sisson and   
            Christine Field and   
            Richard Ventura and   
                 Anne Royou and   
               William Sullivan   Lava Lamp, a Novel Peripheral Golgi
                                  Protein, Is Required for
                                  \bionameDrosophila melanogaster
                                  Cellularization  . . . . . . . . . . . . 905
             E. J. Kamsteeg and   
                 I. Heijnen and   
               C. H. van Os and   
                  P. M. T. Deen   The Subcellular Localization of an
                                  Aquaporin-2 Tetramer Depends on the
                                  Stoichiometry of Phosphorylated and
                                  Nonphosphorylated Monomers . . . . . . . 919
           Fernando Lecanda and   
           Pamela M. Warlow and   
             Sharmin Sheikh and   
            Federico Furlan and   
        Thomas H. Steinberg and   
              Roberto Civitelli   Connexin43 Deficiency Causes Delayed
                                  Ossification, Craniofacial
                                  Abnormalities, and Osteoblast
                                  Dysfunction  . . . . . . . . . . . . . . 931
          Justine Kiessling and   
                 Sven Kruse and   
          Stefan A. Rensing and   
               Klaus Harter and   
              Eva L. Decker and   
                     Ralf Reski   Visualization of a Cytoskeleton-like
                                  Ftsz Network in Chloroplasts . . . . . . 945

Journal of Cell Biology
Volume 151, Number 5, November, 2000

          John D. Aitchison and   
                Michael P. Rout   The Road to Ribosomes  . . . . . . . . . 0
            Edwin W. Taylor and   
                 Gary G. Borisy   Kinesin Processivity . . . . . . . . . . ??
             Ahmed Zahraoui and   
             Daniel Louvard and   
                  Thierry Galli   Tight Junction, a Platform for
                                  Trafficking and Signaling Protein
                                  Complexes  . . . . . . . . . . . . . . . ??
             Mary E. Porter and   
               Winfield S. Sale   The 9 + 2 Axoneme Anchors Multiple Inner
                                  Arm Dyneins and a Network of Kinases and
                                  Phosphatases That Control Motility . . . ??
             Lavina Faleiro and   
                  Yuri Lazebnik   Caspases Disrupt the
                                  Nuclear--Cytoplasmic Barrier . . . . . . 951
                    Ping Hu and   
             Fang-Ming Deng and   
             Feng-Xia Liang and   
               Chuan-Min Hu and   
           Anna B. Auerbach and   
              Ellen Shapiro and   
                  Xue-Ru Wu and   
             Bechara Kachar and   
                  Tung-Tien Sun   Ablation of Uroplakin III Gene Results
                                  in Small Urothelial Plaques, Urothelial
                                  Leakage, and Vesicoureteral Reflux . . . 961
              Yuval Shimoni and   
            Tatsuo Kurihara and   
         Mariella Ravazzola and   
           Myl\`ene Amherdt and   
                 Lelio Orci and   
                 Randy Schekman   Lst1p and Sec24p Cooperate in Sorting of
                                  the Plasma Membrane Atpase into Copii
                                  Vesicles in \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 973
              Stanny Berghs and   
             Diego Aggujaro and   
               Ronald Dirkx and   
            Elena Maksimova and   
               Paul Stabach and   
         Jean-Michel Hermel and   
            Jian-Ping Zhang and   
          William Philbrick and   
           Vladimir Slepnev and   
                Tatiana Ort and   
               Michele Solimena   $ \beta $ iv Spectrin, a New Spectrin
                                  Localized at Axon Initial Segments and
                                  Nodes of Ranvier in the Central and
                                  Peripheral Nervous System  . . . . . . . 985
         Anne-Marie C. Yvon and   
             Patricia Wadsworth   Region-Specific Microtubule Transport in
                                  Motile Cells . . . . . . . . . . . . . . 1003
    Ivelisse Sánchez and   
            Linda Hassinger and   
               Ram K. Sihag and   
           Don W. Cleveland and   
             Panaiyur Mohan and   
                 Ralph A. Nixon   Local Control of Neurofilament
                                  Accumulation during Radial Growth of
                                  Myelinating Axons in Vivo  . . . . . . . 1013
           Hagai Abeliovich and   
            William A. Dunn and   
                   John Kim and   
             Daniel J. Klionsky   Dissection of Autophagosome Biogenesis
                                  into Distinct Nucleation and Expansion
                                  Steps  . . . . . . . . . . . . . . . . . 1025
       Stefano C. Previtali and   
           Angelo Quattrini and   
            Marina Fasolini and   
        Maria Carla Panzeri and   
            Antonello Villa and   
            Marie T. Filbin and   
                  Wenhui Li and   
             Shing-Yan Chiu and   
              Albee Messing and   
           Lawrence Wrabetz and   
                M. Laura Feltri   Epitope-Tagged P$_0$ Glycoprotein Causes
                                  Charcot--Marie--Tooth-like Neuropathy in
                                  Transgenic Mice  . . . . . . . . . . . . 1035
            Shikha Laloraya and   
             Vincent Guacci and   
               Douglas Koshland   Chromosomal Addresses of the Cohesin
                                  Component Mcd1p  . . . . . . . . . . . . 1047
       Jennifer Hei-Ngam Ho and   
           George Kallstrom and   
               Arlen W. Johnson   Nmd3p Is a Crm1p--Dependent Adapter
                                  Protein for Nuclear Export of the Large
                                  Ribosomal Subunit  . . . . . . . . . . . 1057
       Cécile Barret and   
              Christian Roy and   
      Philippe Montcourrier and   
               Paul Mangeat and   
                  Verena Niggli   Mutagenesis of the Phosphatidylinositol
                                  4,5-Bisphosphate (Pip$_2$) Binding Site
                                  in the Nh$_2$-Terminal Domain of Ezrin
                                  Correlates with Its Altered Cellular
                                  Distribution . . . . . . . . . . . . . . 1067
           Michio Tomishige and   
                 Ronald D. Vale   Controlling Kinesin by Reversible
                                  Disulfide Cross--Linking . . . . . . . . 1081
              Kurt S. Thorn and   
         Jeffrey A. Ubersax and   
                 Ronald D. Vale   Engineering the Processive Run Length of
                                  the Kinesin Motor  . . . . . . . . . . . 1093
               Ursula Fleig and   
            Sandra S. Salus and   
                 Inga Karig and   
                  Shelley Sazer   The Fission Yeast Ran Gtpase Is Required
                                  for Microtubule Integrity  . . . . . . . 1101
          Richard D. Shelby and   
              Karine Monier and   
              Kevin F. Sullivan   Chromatin Assembly at Kinetochores Is
                                  Uncoupled from DNA Replication . . . . . 1113
           Noureddine Zebda and   
                Ora Bernard and   
              Maryse Bailly and   
                Susan Welti and   
          David S. Lawrence and   
              John S. Condeelis   Phosphorylation of Adf/Cofilin Abolishes
                                  Egf-Induced Actin Nucleation at the
                                  Leading Edge and Subsequent Lamellipod
                                  Extension  . . . . . . . . . . . . . . . 1119

Journal of Cell Biology
Volume 151, Number 6, December, 2000

         Jeffrey S. Chamberlain   Muscular Dystrophy Meets the Gene Chip   0
         Margaret A. Lawlor and   
                  Peter Rotwein   Coordinate Control of Muscle Cell
                                  Survival by Distinct Insulin-like Growth
                                  Factor Activated Signaling Pathways  . . 1131
          Suresh K. Alahari and   
              Jung Weon Lee and   
                Rudy L. Juliano   Nischarin, a Novel Protein That
                                  Interacts with the Integrin $ \alpha $5
                                  Subunit and Inhibits Cell Migration  . . 1141
             Robert D. Moir and   
                  Miri Yoon and   
                Satya Khuon and   
              Robert D. Goldman   Nuclear Lamins a and B1  . . . . . . . . 1155
           Arabella Meixner and   
            Silke Haverkamp and   
          Heinz Wässle and   
        Susanne Führer and   
          Johann Thalhammer and   
                 Nina Kropf and   
        Reginald E. Bittner and   
              Hans Lassmann and   
              Gerhard Wiche and   
               Friedrich Propst   Map1b Is Required for Axon Guidance and
                                  Is Involved in the Development of the
                                  Central and Peripheral Nervous System    1169
              Hadas Reuveni and   
               Tamar Geiger and   
            Benjamin Geiger and   
             Alexander Levitzki   Reversal of the Ras-Induced Transformed
                                  Phenotype by Hr12, a Novel Ras
                                  Farnesylation Inhibitor, Is Mediated by
                                  the Mek/ERK Pathway  . . . . . . . . . . 1179
               Jae-Beom Kim and   
             Shahidul Islam and   
               Young J. Kim and   
            Ryan S. Prudoff and   
            Kristin M. Sass and   
       Margaret J. Wheelock and   
               Keith R. Johnson   N-Cadherin Extracellular Repeat 4
                                  Mediates Epithelial to Mesenchymal
                                  Transition and Increased Motility  . . . 1193
                Mona Wilcke and   
            Ludger Johannes and   
              Thierry Galli and   
     Véronique Mayau and   
                 Bruno Goud and   
                  Jean Salamero   Rab11 Regulates the Compartmentalization
                                  of Early Endosomes Required for
                                  Efficient Transport from Early Endosomes
                                  to the Trans-Golgi Network . . . . . . . 1207
      Jonathan R. Beauchamp and   
              Louise Heslop and   
             David S. W. Yu and   
        Shahragim Tajbakhsh and   
            Robert G. Kelly and   
               Anton Wernig and   
     Margaret E. Buckingham and   
       Terence A. Partridge and   
                Peter S. Zammit   Expression of Cd34 and Myf5 Defines the
                                  Majority of Quiescent Adult Skeletal
                                  Muscle Satellite Cells . . . . . . . . . 1221
             Chinami Hikita and   
Soundarapandian Vijayakumar and   
                Jiro Takito and   
  Hediyet Erdjument-Bromage and   
                Paul Tempst and   
                 Qais Al-Awqati   Induction of Terminal Differentiation in
                                  Epithelial Cells Requires Polymerization
                                  of Hensin by Galectin 3  . . . . . . . . 1235
         Hirotaka Matsumura and   
             Yusuke Shimizu and   
           Yoshiyuki Ohsawa and   
             Atsuo Kawahara and   
             Yasuo Uchiyama and   
               Shigekazu Nagata   Necrotic Death Pathway in FAS Receptor
                                  Signaling  . . . . . . . . . . . . . . . 1247
             Nancy Kedersha and   
             Michael R. Cho and   
                     Wei Li and   
          Patrick W. Yacono and   
              Samantha Chen and   
              Natalie Gilks and   
             David E. Golan and   
                  Paul Anderson   Dynamic Shuttling of Tia-1 Accompanies
                                  the Recruitment of mRNA to Mammalian
                                  Stress Granules  . . . . . . . . . . . . 1257
             Jason M. Haugh and   
             Franca Codazzi and   
                Mary Teruel and   
                   Tobias Meyer   Spatial Sensing in Fibroblasts Mediated
                                  by 3' Phosphoinositides  . . . . . . . . 1269
          Nathalie Signoret and   
  Annegret Pelchen-Matthews and   
              Matthias Mack and   
     Amanda E. I. Proudfoot and   
                     Mark Marsh   Endocytosis and Recycling of the HIV
                                  Coreceptor Ccr5  . . . . . . . . . . . . 1281
        Alessandro Porrello and   
    Maria Antonietta Cerone and   
               Sabrina Coen and   
             Aymone Gurtner and   
          Giulia Fontemaggi and   
             Letizia Cimino and   
             Giulia Piaggio and   
                 Ada Sacchi and   
                   Silvia Soddu   P53 Regulates Myogenesis by Triggering
                                  the Differentiation Activity of Prb  . . 1295
            Ben B. Whitlock and   
               Shyra Gardai and   
              Valerie Fadok and   
              Donna Bratton and   
                Peter M. Henson   Differential Roles for $ \alpha $$_M$ $
                                  \beta_2$ Integrin Clustering or
                                  Activation in the Control of Apoptosis
                                  via Regulation of Akt and ERK Survival
                                  Mechanisms . . . . . . . . . . . . . . . 1305
                Yi-Wen Chen and   
                    Po Zhao and   
             Rehannah Borup and   
                Eric P. Hoffman   Expression Profiling in the Muscular
                                  Dystrophies  . . . . . . . . . . . . . . 1321
Richard A. Heil-Chapdelaine and   
          Jessica R. Oberle and   
                 John A. Cooper   The Cortical Protein Num1p Is Essential
                                  for Dynein--Dependent Interactions of
                                  Microtubules with the Cortex . . . . . . 1337
            Elisa Santolini and   
               Claudia Puri and   
    Anna Elisabetta Salcini and   
    Maria Cristina Gagliani and   
      Pier Giuseppe Pelicci and   
            Carlo Tacchetti and   
            Pier Paolo Di Fiore   Numb Is an Endocytic Protein . . . . . . 1345

Journal of Cell Biology
Volume 151, Number 7, December, 2000

         Roberto J. Botelho and   
                Mary Teruel and   
            Renee Dierckman and   
           Richard Anderson and   
                 Alan Wells and   
               John D. York and   
               Tobias Meyer and   
               Sergio Grinstein   Localized Biphasic Changes in
                                  Phosphatidylinositol-4,5-Bisphosphate at
                                  Sites of Phagocytosis  . . . . . . . . . 1353
            Beatrice M. Tam and   
            Orson L. Moritz and   
           Lawrence B. Hurd and   
           David S. Papermaster   Identification of an Outer Segment
                                  Targeting Signal in the Cooh Terminus of
                                  Rhodopsin Using Transgenic
                                  \bionameXenopus laevis . . . . . . . . . 1369
           Linda B. Schultz and   
            Nabil H. Chehab and   
              Asra Malikzay and   
          Thanos D. Halazonetis   P53 Binding Protein 1 (53bp1) Is an
                                  Early Participant in the Cellular
                                  Response to DNA Double--Strand Breaks    1381
             Jesse J. Smith and   
             Erica K. Evans and   
            Monica Murakami and   
              Mary B. Moyer and   
          M. Arthur Moseley and   
         George Vande Woude and   
                Sally Kornbluth   Wee1-Regulated Apoptosis Mediated by the
                                  Crk Adaptor Protein in \bionameXenopus
                                  Egg Extracts . . . . . . . . . . . . . . 1391
            Diana L. Walker and   
                  Dong Wang and   
                     Ye Jin and   
                Uttama Rath and   
               Yanming Wang and   
     Jòrgen Johansen and   
            Kristen M. Johansen   Skeletor, a Novel Chromosomal Protein
                                  That Redistributes during Mitosis
                                  Provides Evidence for the Formation of a
                                  Spindle Matrix . . . . . . . . . . . . . 1401
           Erik H. J. Danen and   
            Petra Sonneveld and   
          Arnoud Sonnenberg and   
              Kenneth M. Yamada   Dual Stimulation of
                                  Ras/Mitogen-Activated Protein Kinase and
                                  Rhoa by Cell Adhesion to Fibronectin
                                  Supports Growth Factor-Stimulated Cell
                                  Cycle Progression  . . . . . . . . . . . 1413
             Boris Striepen and   
        Michael J. Crawford and   
            Michael K. Shaw and   
            Lewis G. Tilney and   
               Frank Seeber and   
                  David S. Roos   The Plastid of Toxoplasma gondii Is
                                  Divided by Association with the
                                  Centrosomes  . . . . . . . . . . . . . . 1423
    Sotiris N. Nikolopoulos and   
          Christopher E. Turner   Actopaxin, a New Focal Adhesion Protein
                                  That Binds Paxillin Ld Motifs and Actin
                                  and Regulates Cell Adhesion  . . . . . . 1435
             Mary Ann Sells and   
               Amanda Pfaff and   
              Jonathan Chernoff   Temporal and Spatial Distribution of
                                  Activated Pak1 in Fibroblasts  . . . . . 1449
                    He Wang and   
          David A. D. Parry and   
            Leslie N. Jones and   
           William W. Idler and   
          Lyuben N. Marekov and   
              Peter M. Steinert   In Vitro Assembly and Structure of
                                  Trichocyte Keratin Intermediate
                                  Filaments  . . . . . . . . . . . . . . . 1459
                Andy Golden and   
            Penny L. Sadler and   
      Matthew R. Wallenfang and   
         Jill M. Schumacher and   
         Danielle R. Hamill and   
                Gayle Bates and   
             Bruce Bowerman and   
          Geraldine Seydoux and   
                Diane C. Shakes   Metaphase to Anaphase (mat)
                                  Transition--Defective Mutants in
                                  \bionameCaenorhabditis elegans . . . . . 1469
              Mary C. Reedy and   
            Belinda Bullard and   
               Jim O. Vigoreaux   Flightin Is Essential for Thick Filament
                                  Assembly and Sarcomere Stability in
                                  \bionameDrosophila Flight Muscles  . . . 1483
               Matthew Lord and   
             Melody C. Yang and   
           Michelle Mischke and   
                     John Chant   Cell Cycle Programs of Gene Expression
                                  Control Morphogenetic Protein
                                  Localization . . . . . . . . . . . . . . 1501
    Ruwanthi N. Gunawardane and   
              Ona C. Martin and   
                    Kan Cao and   
                Lijun Zhang and   
               Kimberly Dej and   
           Akihiro Iwamatsu and   
                   Yixian Zheng   Characterization and Reconstitution of
                                  \bionameDrosophila $ \gamma $-Tubulin
                                  Ring Complex Subunits  . . . . . . . . . 1513
                Lijun Zhang and   
          Thomas J. Keating and   
               Andrew Wilde and   
             Gary G. Borisy and   
                   Yixian Zheng   The Role of Xgrip210 in $ \gamma
                                  $-Tubulin Ring Complex Assembly and
                                  Centrosome Recruitment . . . . . . . . . 1525
               Rolf Heumann and   
          Christoph Goemans and   
            Daniela Bartsch and   
       Kurt Lingenhöhl and   
         Peter C. Waldmeier and   
           Bastian Hengerer and   
         Peter R. Allegrini and   
           Karl Schellander and   
            Erwin F. Wagner and   
              Thomas Arendt and   
         Rigobert H. Kamdem and   
      Kirstin Obst-Pernberg and   
                 Frank Narz and   
                Petra Wahle and   
                  Hartmut Berns   Transgenic Activation of Ras in Neurons
                                  Promotes Hypertrophy and Protects from
                                  Lesion--Induced Degeneration . . . . . . 1537
         Allison L. Berrier and   
     Anthony M. Mastrangelo and   
            Julian Downward and   
              Mark Ginsberg and   
              Susan E. LaFlamme   Activated R--Ras, Rac1, Pi 3-Kinase and
                                  Pkc$ \epsilon $ Can Each Restore Cell
                                  Spreading Inhibited by Isolated Integrin
                                  $ \beta $1 Cytoplasmic Domains . . . . . 1549
          Melpomeni Platani and   
              Ilya Goldberg and   
           Jason R. Swedlow and   
                Angus I. Lamond   In Vivo Analysis of Cajal Body Movement,
                                  Separation, and Joining in Live Human
                                  Cells  . . . . . . . . . . . . . . . . . 1561
      Dimitrios A. Skoufias and   
        Cristiana Mollinari and   
Françoise B. Lacroix and   
             Robert L. Margolis   Human Survivin Is a
                                  Kinetochore--Associated Passenger
                                  Protein  . . . . . . . . . . . . . . . . 1575
           Isabelle Richard and   
            Carinne Roudaut and   
            Sylvie Marchand and   
        Stephen Baghdiguian and   
             Muriel Herasse and   
           Daniel Stockholm and   
                 Yasuko Ono and   
              Laurence Suel and   
             Nathalie Bourg and   
         Hiroyuki Sorimachi and   
      Gérard Lefranc and   
             Michel Fardeau and   
       Alain Sébille and   
            Jacques S. Beckmann   Loss of Calpain 3 Proteolytic Activity
                                  Leads to Muscular Dystrophy and to
                                  Apoptosis-Associated I$ \kappa $ b$
                                  \alpha $/Nuclear Factor $ \kappa $ b
                                  Pathway Perturbation in Mice . . . . . . 1583
         Arunas A. Gineitis and   
        Irina A. Zalenskaya and   
               Peter M. Yau and   
         E. Morton Bradbury and   
             Andrei O. Zalensky   Human Sperm Telomere--Binding Complex
                                  Involves Histone H2b and Secures
                                  Telomere Membrane Attachment . . . . . . 1591


Journal of Cell Biology
Volume 152, Number 1, January, 2001

                Eva Nogales and   
            Nikolaus Grigorieff   Molecular Machines . . . . . . . . . . . 0
            Sari Ben-Yaacov and   
           Roland Le Borgne and   
              Irit Abramson and   
François Schweisguth and   
               Eyal D. Schejter   Wasp, the \bionameDrosophila
                                  Wiskott--Aldrich Syndrome Gene
                                  Homologue, Is Required for Cell Fate
                                  Decisions Mediated by Notch Signaling    1
             J. Julian Blow and   
         Peter J. Gillespie and   
             Dennis Francis and   
                Dean A. Jackson   Replication Origins in \bionameXenopus
                                  Egg Extract Are 5--15 Kilobases Apart
                                  and Are Activated in Clusters That Fire
                                  at Different Times . . . . . . . . . . . 15
               Sanne Jensen and   
               Marisa Segal and   
           Duncan J. Clarke and   
                 Steven I. Reed   A Novel Role of the Budding Yeast
                                  Separin Esp1 in Anaphase Spindle
                                  Elongation . . . . . . . . . . . . . . . 27
             Stefan Hillmer and   
              Ali Movafeghi and   
          David G. Robinson and   
                 Giselbert Hinz   Vacuolar Storage Proteins Are Sorted in
                                  the Cis--Cisternae of the Pea Cotyledon
                                  Golgi Apparatus  . . . . . . . . . . . . 41
                   John Kim and   
             Wei-Pang Huang and   
             Daniel J. Klionsky   Membrane Recruitment of Aut7p in the
                                  Autophagy and Cytoplasm to Vacuole
                                  Targeting Pathways Requires Aut1p,
                                  Aut2p, and the Autophagy Conjugation
                                  Complex  . . . . . . . . . . . . . . . . 51
               Tieming Zhao and   
                Peter J. Newman   Integrin Activation by Regulated
                                  Dimerization and Oligomerization of
                                  Platelet Endothelial Cell Adhesion
                                  Molecule (Pecam)-1 from within the Cell  65
           Livio Pellizzoni and   
           Bernard Charroux and   
            Juri Rappsilber and   
              Matthias Mann and   
                Gideon Dreyfuss   A Functional Interaction between the
                                  Survival Motor Neuron Complex and RNA
                                  Polymerase II  . . . . . . . . . . . . . 75
             Shaoqiong Chen and   
         Denis C. Guttridge and   
               Zongbing You and   
             Zhaochen Zhang and   
             Andrew Fribley and   
              Marty W. Mayo and   
             Jan Kitajewski and   
                    Cun-Yu Wang   WNT-1 Signaling Inhibits Apoptosis by
                                  Activating $ \beta $-Catenin/T Cell
                                  Factor-Mediated Transcription  . . . . . 87
       Candice K. Klingbeil and   
          Christof R. Hauck and   
             Datsun A. Hsia and   
                K. C. Jones and   
          Shannon R. Reider and   
            David D. Schlaepfer   Targeting Pyk2 to $ \beta
                                  $1--Integrin--Containing Focal Contacts
                                  Rescues Fibronectin--Stimulated
                                  Signaling and Haptotactic Motility
                                  Defects of Focal Adhesion Kinase--Null
                                  Cells  . . . . . . . . . . . . . . . . . 97
           David Michaelson and   
            Joseph Silletti and   
            Gretchen Murphy and   
          Peter D'Eustachio and   
                  Mark Rush and   
                Mark R. Philips   Differential Localization of Rho Gtpases
                                  in Live Cells  . . . . . . . . . . . . . 111
           James M. Holaska and   
               Ben E. Black and   
               Dona C. Love and   
            John A. Hanover and   
                John Leszyk and   
               Bryce M. Paschal   Calreticulin Is a Receptor for Nuclear
                                  Export . . . . . . . . . . . . . . . . . 127
               Ben E. Black and   
           James M. Holaska and   
       Lyne Lévesque and   
      Batool Ossareh-Nazari and   
              Carol Gwizdek and   
        Catherine Dargemont and   
               Bryce M. Paschal   Nxt1 Is Necessary for the Terminal Step
                                  of Crm1-Mediated Nuclear Export  . . . . 141
      Valerie A. Kickhoefer and   
                    Yie Liu and   
           Lawrence B. Kong and   
              Bryan E. Snow and   
          Phoebe L. Stewart and   
             Lea Harrington and   
                Leonard H. Rome   The Telomerase/Vault-Associated Protein
                                  Tep1 Is Required for Vault RNA Stability
                                  and Its Association with the Vault
                                  Particle . . . . . . . . . . . . . . . . 157
        Jérome Garin and   
               Roberto Diez and   
             Sylvie Kieffer and   
Jean-François Dermine and   
              Sophie Duclos and   
             Etienne Gagnon and   
                Remy Sadoul and   
         Christiane Rondeau and   
              Michel Desjardins   The Phagosome Proteome . . . . . . . . . 165
             Archana Sanjay and   
              Adam Houghton and   
                  Lynn Neff and   
          Emilia DiDomenico and   
           Chantal Bardelay and   
            Evelyne Antoine and   
                  Joan Levy and   
               James Gailit and   
              David Bowtell and   
           William C. Horne and   
                   Roland Baron   Cbl Associates with Pyk2 and Src to
                                  Regulate Src Kinase Activity, $ \alpha_v
                                  \beta_3 $ Integrin-Mediated Signaling,
                                  Cell Adhesion, and Osteoclast Motility   181
          Iain M. Cheeseman and   
       Maria Enquist-Newman and   
Thomas Müller-Reichert and   
            David G. Drubin and   
                Georjana Barnes   Mitotic Spindle Integrity and
                                  Kinetochore Function Linked by the
                                  Duo1p/Dam1p Complex  . . . . . . . . . . 197
                Meir Aridor and   
            Kenneth N. Fish and   
             Sergei Bannykh and   
           Jacques Weissman and   
         Theresa H. Roberts and   
Jennifer Lippincott-Schwartz and   
               William E. Balch   The Sar1 Gtpase Coordinates Biosynthetic
                                  Cargo Selection with Endoplasmic
                                  Reticulum Export Site Assembly . . . . . 213
            Laurie G. Smith and   
        Suzanne M. Gerttula and   
             Shengcheng Han and   
                    Joshua Levy   Tangled1 . . . . . . . . . . . . . . . . 231

Journal of Cell Biology
Volume 152, Number 2, January, 2001

               David M. Gilbert   Nuclear Position Leaves Its Mark on
                                  Replication Timing . . . . . . . . . . . 0
           Shigeomi Shimizu and   
            Yosuke Matsuoka and   
            Yasuo Shinohara and   
           Yoshihiro Yoneda and   
            Yoshihide Tsujimoto   Essential Role of Voltage--Dependent
                                  Anion Channel in Various Forms of
                                  Apoptosis in Mammalian Cells . . . . . . 237
         Marian Farkasovsky and   
              Hans Küntzel   Cortical Num1p Interacts with the Dynein
                                  Intermediate Chain Pac11p and
                                  Cytoplasmic Microtubules in Budding
                                  Yeast  . . . . . . . . . . . . . . . . . 251
          Michael F. Crouch and   
            Deborah A. Davy and   
         Francis S. Willard and   
                Leise A. Berven   Activation of Endogenous Thrombin
                                  Receptors Causes Clustering and
                                  Sensitization of Epidermal Growth Factor
                                  Receptors of Swiss 3t3 Cells without
                                  Transactivation  . . . . . . . . . . . . 263
             Akira Kawasaki and   
            Itaru Matsumura and   
        Jun-ichiro Miyagawa and   
               Sachiko Ezoe and   
            Hirokazu Tanaka and   
            Yasuhiko Terada and   
            Masaaki Tatsuka and   
             Takashi Machii and   
           Hiroshi Miyazaki and   
            Yusuke Furukawa and   
                Yuzuru Kanakura   Downregulation of an Aim-1 Kinase
                                  Couples with Megakaryocytic
                                  Polyploidization of Human Hematopoietic
                                  Cells  . . . . . . . . . . . . . . . . . 275
             Thomas Krimmer and   
             Doron Rapaport and   
            Michael T. Ryan and   
            Chris Meisinger and   
     C. Kenneth Kassenbrock and   
    Elizabeth Blachly-Dyson and   
              Michael Forte and   
         Michael G. Douglas and   
             Walter Neupert and   
           Frank E. Nargang and   
               Nikolaus Pfanner   Biogenesis of Porin of the Outer
                                  Mitochondrial Membrane Involves an
                                  Import Pathway via Receptors and the
                                  General Import Pore of the Tom Complex   289
           Stefano Carenini and   
        Mathias Mäurer and   
           Alexander Werner and   
           Heinrich Blazyca and   
             Klaus V. Toyka and   
        Christoph D. Schmid and   
           Gennadij Raivich and   
                 Rudolf Martini   The Role of Macrophages in Demyelinating
                                  Peripheral Nervous System of Mice
                                  Heterozygously Deficient in P0 . . . . . 301
                Elaine Hill and   
        Jeroen van der Kaay and   
            C. Peter Downes and   
               Elizabeth Smythe   The Role of Dynamin and Its Binding
                                  Partners in Coated Pit Invagination and
                                  Scission . . . . . . . . . . . . . . . . 309
             Heike Keilhack and   
          Marit Müller and   
 Sylvia-Annette Böhmer and   
              Carsten Frank and   
         K. Michael Weidner and   
          Walter Birchmeier and   
              Tanja Ligensa and   
           Alexander Berndt and   
            Hartwig Kosmehl and   
         Bernd Günther and   
         Thomas Müller and   
          Carmen Birchmeier and   
           Frank D. Böhmer   Negative Regulation of Ros Receptor
                                  Tyrosine Kinase Signaling  . . . . . . . 325
              Yuan Torrente and   
         Jacques-P Tremblay and   
            Federica Pisati and   
            Marzia Belicchi and   
              Barbara Rossi and   
             Manuela Sironi and   
           Franco Fortunato and   
          Mostafa El Fahime and   
      Maria Grazia D'Angelo and   
           Nicolas J. Caron and   
        Gabriela Constantin and   
              Denise Paulin and   
         Guglielmo Scarlato and   
                 Nereo Bresolin   Intraarterial Injection of
                                  Muscle--Derived Cd34$^+$ Sca-1$^+$ Stem
                                  Cells Restores Dystrophin in mdx Mice    335
            Philip A. Wigge and   
              John V. Kilmartin   The Ndc80p Complex from
                                  \bionameSaccharomyces cerevisiae
                                  Contains Conserved Centromere Components
                                  and Has a Function in Chromosome
                                  Segregation  . . . . . . . . . . . . . . 349
            Ichiro Nakamura and   
           Lorraine Lipfert and   
            Gideon A. Rodan and   
                    Le T. Duong   Convergence of $ \alpha_v \beta_3 $
                                  Integrin- and Macrophage Colony
                                  Stimulating Factor-Mediated Signals on
                                  Phospholipase C$ \gamma $ in Prefusion
                                  Osteoclasts  . . . . . . . . . . . . . . 361
          Brian P. Chadwick and   
          Huntington F. Willard   A Novel Chromatin Protein, Distantly
                                  Related to Histone H2a, Is Largely
                                  Excluded from the Inactive X Chromosome  375
               Patrick Heun and   
            Thierry Laroche and   
           M. K. Raghuraman and   
                Susan M. Gasser   The Positioning and Dynamics of Origins
                                  of Replication in the Budding Yeast
                                  Nucleus  . . . . . . . . . . . . . . . . 385
      Alyson E. Aiken Hobbs and   
      Maithreyan Srinivasan and   
       J. Michael McCaffery and   
               Robert E. Jensen   Mmm1p, a Mitochondrial Outer Membrane
                                  Protein, Is Connected to Mitochondrial
                                  DNA (Mtdna) Nucleoids and Required for
                                  Mtdna Stability  . . . . . . . . . . . . 401
            Iris Ben-Efraim and   
                   Larry Gerace   Gradient of Increasing Affinity of
                                  Importin $ \beta $ for Nucleoporins
                                  along the Pathway of Nuclear Import  . . 411

Journal of Cell Biology
Volume 152, Number 3, February, 2001

          Michael B. Gordon and   
              Louisa Howard and   
               Duane A. Compton   Chromosome Movement in Mitosis Requires
                                  Microtubule Anchorage at Spindle Poles   425
         Christian Jacobson and   
Patrice D. Côté and   
            Susana G. Rossi and   
         Richard L. Rotundo and   
           Salvatore Carbonetto   The Dystroglycan Complex Is Necessary
                                  for Stabilization of Acetylcholine
                                  Receptor Clusters at Neuromuscular
                                  Junctions and Formation of the Synaptic
                                  Basement Membrane  . . . . . . . . . . . 435
                Sukgil Song and   
                   Kyung S. Lee   A Novel Function of
                                  \bionameSaccharomyces cerevisiae CDC5 in
                                  Cytokinesis  . . . . . . . . . . . . . . 451
              Maiko Fukuoka and   
             Shiro Suetsugu and   
               Hiroaki Miki and   
              Kiyoko Fukami and   
               Takeshi Endo and   
               Tadaomi Takenawa   A Novel Neural Wiskott--Aldrich Syndrome
                                  Protein (N--Wasp) Binding Protein, Wish,
                                  Induces Arp2/3 Complex Activation
                                  Independent of Cdc42 . . . . . . . . . . 471
              Paul G. Ekert and   
                 John Silke and   
       Christine J. Hawkins and   
           Anne M. Verhagen and   
                  David L. Vaux   Diablo Promotes Apoptosis by Removing
                                  Miha/Xiap from Processed Caspase 9 . . . 483
      Anke Reinacher-Schick and   
              Barry M. Gumbiner   Apical Membrane Localization of the
                                  Adenomatous Polyposis Coli Tumor
                                  Suppressor Protein and Subcellular
                                  Distribution of the $ \beta $-Catenin
                                  Destruction Complex in Polarized
                                  Epithelial Cells . . . . . . . . . . . . 491
                Stefan Otte and   
          William J. Belden and   
           Matthew Heidtman and   
                    Jay Liu and   
              Ole N. Jensen and   
                Charles Barlowe   Erv41p and Erv46p  . . . . . . . . . . . 503
                Akio Kihara and   
               Takeshi Noda and   
           Naotada Ishihara and   
               Yoshinori Ohsumi   Two Distinct Vps34 Phosphatidylinositol
                                  3--Kinase Complexes Function in
                                  Autophagy and Carboxypeptidase Y Sorting
                                  in \bionameSaccharomyces cerevisiae  . . 519
           Farhah F. Assaad and   
                 Yoann Huet and   
               Ulrike Mayer and   
              Gerd Jürgens   The Cytokinesis Gene KEULE Encodes a
                                  Sec1 Protein That Binds the Syntaxin
                                  Knolle . . . . . . . . . . . . . . . . . 531
              Tord A. Hjalt and   
             Brad A. Amendt and   
              Jeffrey C. Murray   Pitx2 Regulates Procollagen Lysyl
                                  Hydroxylase (Plod) Gene Expression . . . 545
        Per Nòrgaard and   
            Vibeke Westphal and   
        Christine Tachibana and   
          Lene Alsòe and   
         Bjòrn Holst and   
               Jakob R. Winther   Functional Differences in Yeast Protein
                                  Disulfide Isomerases . . . . . . . . . . 553
             Matthias Reiss and   
              Nicola Viebig and   
               Susan Brecht and   
      Marie-Noelle Fourmaux and   
              Martine Soete and   
         Manlio Di Cristina and   
Jean François Dubremetz and   
              Dominique Soldati   Identification and Characterization of
                                  an Escorter for Two Secretory Adhesins
                                  in \bionameToxoplasma gondii . . . . . . 563
              Sheila Govind and   
               Robert Kozma and   
           Clinton Monfries and   
                  Louis Lim and   
                   Sohail Ahmed   Cdc42hs Facilitates Cytoskeletal
                                  Reorganization and Neurite Outgrowth by
                                  Localizing the 58-Kd Insulin Receptor
                                  Substrate to Filamentous Actin . . . . . 579
          Heike Fölsch and   
               Marc Pypaert and   
                 Peter Schu and   
                    Ira Mellman   Distribution and Function of Ap-1
                                  Clathrin Adaptor Complexes in Polarized
                                  Epithelial Cells . . . . . . . . . . . . 595
          Sherri L. Newmyer and   
               Sandra L. Schmid   Dominant-Interfering Hsc70 Mutants
                                  Disrupt Multiple Stages of the
                                  Clathrin--Coated Vesicle Cycle in Vivo   607
              Saskia van Es and   
            Deborah Wessels and   
              David R. Soll and   
               Jane Borleis and   
             Peter N. Devreotes   Tortoise, a Novel Mitochondrial Protein,
                                  Is Required for Directional Responses of
                                  \bionameDictyostelium in Chemotactic
                                  Gradients  . . . . . . . . . . . . . . . 621
              Fawzi Aoudjit and   
                Kristiina Vuori   Matrix Attachment Regulates FAS--Induced
                                  Apoptosis in Endothelial Cells . . . . . 633
              Meral J. Arin and   
           Mary Ann Longley and   
             Xiao-Jing Wang and   
                 Dennis R. Roop   Focal Activation of a Mutant Allele
                                  Defines the Role of Stem Cells in Mosaic
                                  Skin Disorders . . . . . . . . . . . . . 645
                 Tongyu Cao and   
           Mary Ann Longley and   
             Xiao-Jing Wang and   
                 Dennis R. Roop   An Inducible Mouse Model for
                                  Epidermolysis Bullosa Simplex  . . . . . 651

Journal of Cell Biology
Volume 152, Number 4, February, 2001

           Bart De Strooper and   
                    Wim Annaert   Where Notch and WNT Signaling Meet . . . 0
             Sean W. Deacon and   
            Vladimir I. Gelfand   Of Yeast, Mice, and Men  . . . . . . . . ??
           Noboru Mizushima and   
          Akitsugu Yamamoto and   
            Masahiko Hatano and   
        Yoshinori Kobayashi and   
              Yukiko Kabeya and   
            Kuninori Suzuki and   
           Takeshi Tokuhisa and   
           Yoshinori Ohsumi and   
              Tamotsu Yoshimori   Dissection of Autophagosome Formation
                                  Using Apg5-Deficient Mouse Embryonic
                                  Stem Cells . . . . . . . . . . . . . . . 657
          Régis Giet and   
                David M. Glover   Drosophila Aurora B Kinase Is Required
                                  for Histone H3 Phosphorylation and
                                  Condensin Recruitment during Chromosome
                                  Condensation and to Organize the Central
                                  Spindle during Cytokinesis . . . . . . . 669
               Stefan Fritz and   
             Doron Rapaport and   
          Elisabeth Klanner and   
             Walter Neupert and   
            Benedikt Westermann   Connection of the Mitochondrial Outer
                                  and Inner Membranes by Fzo1 Is Critical
                                  for Organellar Fusion  . . . . . . . . . 683
      Caroline M. Alexander and   
          Sushma Selvarajan and   
               John Mudgett and   
                      Zena Werb   Stromelysin-1 Regulates Adipogenesis
                                  during Mammary Gland Involution  . . . . 693
              Jeanne L. Dul and   
             David P. Davis and   
       Edward K. Williamson and   
            Fred J. Stevens and   
                     Yair Argon   Hsp70 and Antifibrillogenic Peptides
                                  Promote Degradation and Inhibit
                                  Intracellular Aggregation of
                                  Amyloidogenic Light Chains . . . . . . . 705
                Claire Bony and   
                Serge Roche and   
               Ueno Shuichi and   
            Takehiko Sasaki and   
       Michael A. Crackower and   
            Josef Penninger and   
              Hiroyuki Mano and   
           Michel Pucéat   A Specific Role of Phosphatidylinositol
                                  3--Kinase $ \gamma $ . . . . . . . . . . 717
           Kimihisa Yoshida and   
             Günter Blobel   The Karyopherin Kap142p/Msn5p Mediates
                                  Nuclear Import and Nuclear Export of
                                  Different Cargo Proteins . . . . . . . . 729
              Donna J. Webb and   
            Keena S. Thomas and   
               Steven L. Gonias   Plasminogen Activator Inhibitor 1
                                  Functions as a Urokinase Response
                                  Modifier at the Level of Cell Signaling
                                  and Thereby Promotes Mcf-7 Cell Growth   741
            Nguyen Truc Bui and   
            Antonia Livolsi and   
Jean-François Peyron and   
             Jochen H. M. Prehn   Activation of Nuclear Factor $ \kappa $
                                  b and bcl-x Survival Gene Expression by
                                  Nerve Growth Factor Requires Tyrosine
                                  Phosphorylation of I$ \kappa $B$ \alpha
                                  $  . . . . . . . . . . . . . . . . . . . 753
        Winfried Wunderlich and   
               Irene Fialka and   
                 David Teis and   
                  Arno Alpi and   
             Andrea Pfeifer and   
           Robert G. Parton and   
       Friedrich Lottspeich and   
                 Lukas A. Huber   A Novel 14-Kilodalton Protein Interacts
                                  with the Mitogen-Activated Protein
                                  Kinase Scaffold Mp1 on a Late
                                  Endosomal/Lysosomal Compartment  . . . . 765
               Khalid Bajou and   
    Véronique Masson and   
           Robert D. Gerard and   
           Petra M. Schmitt and   
      Valérie Albert and   
              Michael Praus and   
               Leif R. Lund and   
         Thomas L. Frandsen and   
               Nils Brunner and   
                  Keld Dano and   
         Norbert E. Fusenig and   
              Ulrich Weidle and   
            Geert Carmeliet and   
            David Loskutoff and   
       Desiré Collen and   
            Peter Carmeliet and   
        Jean Michel Foidart and   
              Agn\`es Noël   The Plasminogen Activator Inhibitor
                                  PAI-1 Controls in Vivo Tumor
                                  Vascularization by Interaction with
                                  Proteases, Not Vitronectin . . . . . . . 777
           Salvador Soriano and   
              David E. Kang and   
                   Maofu Fu and   
            Richard Pestell and   
        Nathalie Chevallier and   
                  Hui Zheng and   
                  Edward H. Koo   Presenilin 1 Negatively Regulates $
                                  \beta $-Catenin/T Cell Factor/Lymphoid
                                  Enhancer Factor-1 Signaling
                                  Independently of $ \beta $-Amyloid
                                  Precursor Protein and Notch Processing   785
           Alistair N. Hume and   
          Lucy M. Collinson and   
              Andrzej Rapak and   
             Anita Q. Gomes and   
           Colin R. Hopkins and   
               Miguel C. Seabra   Rab27a Regulates the Peripheral
                                  Distribution of Melanosomes in
                                  Melanocytes  . . . . . . . . . . . . . . 795
        Graça Raposo and   
             Danielle Tenza and   
            Diane M. Murphy and   
           Joanne F. Berson and   
               Michael S. Marks   Distinct Protein Sorting and
                                  Localization to Premelanosomes,
                                  Melanosomes, and Lysosomes in Pigmented
                                  Melanocytic Cells  . . . . . . . . . . . 809
        Jane C. Stinchcombe and   
           Duarte C. Barral and   
            Emilie H. Mules and   
                Sarah Booth and   
           Alistair N. Hume and   
          Laura M. Machesky and   
           Miguel C. Seabra and   
           Gillian M. Griffiths   Rab27a Is Required for Regulated
                                  Secretion in Cytotoxic T Lymphocytes . . 825
            Elias K. Haddad and   
                  Xufeng Wu and   
             John A. Hammer and   
              Pierre A. Henkart   Defective Granule Exocytosis in
                                  Rab27a--Deficient Lymphocytes from Ashen
                                  Mice . . . . . . . . . . . . . . . . . . 835
         Philippe Bahadoran and   
              Edith Aberdam and   
Frédéric Mantoux and   
              Roser Busc\`a and   
               Karine Bille and   
               Nevin Yalman and   
Genevi\`eve de Saint-Basile and   
    Ricardo Casaroli-Marano and   
          Jean-Paul Ortonne and   
                Robert Ballotti   Rab27a . . . . . . . . . . . . . . . . . 843
            Jill L. Johnson and   
             Elizabeth A. Craig   An Essential Role for the
                                  Substrate--Binding Region of Hsp40s in
                                  \bionameSaccharomyces cerevisiae . . . . 851

Journal of Cell Biology
Volume 152, Number 5, March, 2001

               P. J. Hollenbeck   Kinesin Delivers . . . . . . . . . . . . 0
                Gerrit van Meer   Caveolin, Cholesterol, and Lipid
                                  Droplets?  . . . . . . . . . . . . . . . ??
              Betty Y. Poon and   
        Christopher A. Ward and   
            Conan B. Cooper and   
             Wayne R. Giles and   
              Alan R. Burns and   
                     Paul Kubes   $ \alpha $$_4$ -Integrin Mediates
                                  Neutrophil--Induced Free Radical Injury
                                  to Cardiac Myocytes  . . . . . . . . . . 857
            Masaya Yamamoto and   
        Donald H. Hilgemann and   
                  Siyi Feng and   
              Haruhiko Bito and   
         Hisamitsu Ishihara and   
        Yoshikazu Shibasaki and   
                   Helen L. Yin   Phosphatidylinositol 4,5-Bisphosphate
                                  Induces Actin Stress--Fiber Formation
                                  and Inhibits Membrane Ruffling in Cv1
                                  Cells  . . . . . . . . . . . . . . . . . 867
               Ya-sheng Gao and   
                Elizabeth Sztul   A Novel Interaction of the Golgi Complex
                                  with the Vimentin Intermediate Filament
                                  Cytoskeleton . . . . . . . . . . . . . . 877
              Wilma Hofmann and   
             Beate Reichart and   
               Andrea Ewald and   
       Eleonora Müller and   
               Iris Schmitt and   
          Roland H. Stauber and   
       Friedrich Lottspeich and   
       Brigitte M. Jockusch and   
              Ulrich Scheer and   
             Joachim Hauber and   
     Marie-Christine Dabauvalle   Cofactor Requirements for Nuclear Export
                                  of Rev Response Element (Rre)--And
                                  Constitutive Transport Element
                                  (Cte)--Containing Retroviral RNAs  . . . 895
              Lasse Lehnert and   
            Markus M. Lerch and   
                Yohei Hirai and   
          Marie-Luise Kruse and   
            Wolff Schmiegel and   
                Holger Kalthoff   Autocrine Stimulation of Human
                                  Pancreatic Duct-like Development by
                                  Soluble Isoforms of Epimorphin in Vitro  911
           Jason H. Walenta and   
            Aaron J. Didier and   
                 Xinran Liu and   
             Helmut Krämer   The Golgi--Associated Hook3 Protein Is a
                                  Member of a Novel Family of
                                  Microtubule--Binding Proteins  . . . . . 923
                   Ken Sato and   
                Miyuki Sato and   
                 Akihiko Nakano   Rer1p, a Retrieval Receptor for
                                  Endoplasmic Reticulum Membrane Proteins,
                                  Is Dynamically Localized to the Golgi
                                  Apparatus by Coatomer  . . . . . . . . . 935
       Viji Mythily Draviam and   
            Simona Orrechia and   
                Martin Lowe and   
              Ruggero Pardi and   
                 Jonathon Pines   The Localization of Human Cyclins B1 and
                                  B2 Determines Cdk1 Substrate Specificity
                                  and Neither Enzyme Requires Mek to
                                  Disassemble the Golgi Apparatus  . . . . 945
          Kristen J. Verhey and   
                Debra Meyer and   
        Reneé Deehan and   
                John Blenis and   
           Bruce J. Schnapp and   
            Tom A. Rapoport and   
                   Ben Margolis   Cargo of Kinesin Identified as Jip
                                  Scaffolding Proteins and Associated
                                  Signaling Molecules  . . . . . . . . . . 959
               Xiu-Rong Ren and   
              Quan-Sheng Du and   
           Yang-Zhong Huang and   
                Shi-Zhou Ao and   
                    Lin Mei and   
                Wen-Cheng Xiong   Regulation of Cdc42 Gtpase by
                                  Proline-Rich Tyrosine Kinase 2
                                  Interacting with Psgap, a Novel
                                  Pleckstrin Homology and Src Homology 3
                                  Domain Containing Rhogap Protein . . . . 971
               Chin-Yi Chen and   
             Jeanine Graham and   
                       Hong Yan   Evidence for a Replication Function of
                                  Ffa-1, the \bionameXenopus Orthologue of
                                  Werner Syndrome Protein  . . . . . . . . 985
                Shirlee Tan and   
               Nikunj Somia and   
               Pamela Maher and   
                 David Schubert   Regulation of Antioxidant Metabolism by
                                  Translation Initiation Factor 2$ \alpha
                                  $  . . . . . . . . . . . . . . . . . . . 997
         Christos G. Zervas and   
         Stephen L. Gregory and   
              Nicholas H. Brown   Drosophila Integrin--Linked Kinase Is
                                  Required at Sites of Integrin Adhesion
                                  to Link the Cytoskeleton to the Plasma
                                  Membrane . . . . . . . . . . . . . . . . 1007
                    Ying Fu and   
                   Guang Wu and   
                  Zhenbiao Yang   ROP Gtpase--Dependent Dynamics of
                                  Tip--Localized F--Actin Controls Tip
                                  Growth in Pollen Tubes . . . . . . . . . 1019
                Nurul Kabir and   
         Andrew W. Schaefer and   
              Arash Nakhost and   
            Wayne S. Sossin and   
                  Paul Forscher   Protein Kinase C Activation Promotes
                                  Microtubule Advance in Neuronal Growth
                                  Cones by Increasing Average Microtubule
                                  Growth Lifetimes . . . . . . . . . . . . 1033
              Clair Baldock and   
          Abraham J. Koster and   
               Ulrike Ziese and   
            Matthew J. Rock and   
        Michael J. Sherratt and   
             Karl E. Kadler and   
     C. Adrian Shuttleworth and   
                  Cay M. Kielty   The Supramolecular Organization of
                                  Fibrillin--Rich Microfibrils . . . . . . 1045
                 Albert Pol and   
        Robert Luetterforst and   
           Margaret Lindsay and   
                Sanna Heino and   
               Elina Ikonen and   
               Robert G. Parton   A Caveolin Dominant Negative Mutant
                                  Associates with Lipid Bodies and Induces
                                  Intracellular Cholesterol Imbalance  . . 1057
         Anne G. Ostermeyer and   
              James M. Paci and   
               Youchun Zeng and   
          Douglas M. Lublin and   
                 Sean Munro and   
               Deborah A. Brown   Accumulation of Caveolin in the
                                  Endoplasmic Reticulum Redirects the
                                  Protein to Lipid Storage Droplets  . . . 1071
           Toyoshi Fujimoto and   
               Hiroshi Kogo and   
            Kimiko Ishiguro and   
                Kumi Tauchi and   
                   Ryuji Nomura   Caveolin-2 Is Targeted to Lipid
                                  Droplets, a New ``Membrane Domain'' in
                                  the Cell . . . . . . . . . . . . . . . . 1079
Maria-Antonietta Impagnatiello and   
             Stefan Weitzer and   
             Grainne Gannon and   
            Amelia Compagni and   
                Matt Cotten and   
            Gerhard Christofori   Mammalian Sprouty-1 and -2 Are
                                  Membrane-Anchored Phosphoprotein
                                  Inhibitors of Growth Factor Signaling in
                                  Endothelial Cells  . . . . . . . . . . . 1087
François-Michel Boisvert and   
         Michael J. Kruhlak and   
                Alan K. Box and   
         Michael J. Hendzel and   
          David P. Bazett-Jones   The Transcription Coactivator Cbp Is a
                                  Dynamic Component of the Promyelocytic
                                  Leukemia Nuclear Body  . . . . . . . . . 1099
      Carmen Cifuentes-Diaz and   
               Tony Frugier and   
       Francesco D. Tiziano and   
        Emmanuelle Lac\`ene and   
             Natacha Roblot and   
              Vandana Joshi and   
        Marie Helene Moreau and   
                   Judith Melki   Deletion of Murine SMN Exon 7 Directed
                                  to Skeletal Muscle Leads to Severe
                                  Muscular Dystrophy . . . . . . . . . . . 1107
               Margot Thome and   
              Olivier Gaide and   
            Olivier Micheau and   
             Fabio Martinon and   
               David Bonnet and   
        Montserrat Gonzalez and   
              Jürg Tschopp   Equine Herpesvirus Protein E10 Induces
                                  Membrane Recruitment and Phosphorylation
                                  of Its Cellular Homologue, Bcl-10  . . . 1115

Journal of Cell Biology
Volume 152, Number 6, March, 2001

                Bruce R. Zetter   Hold That Line . . . . . . . . . . . . . 0
              Hiromi Sesaki and   
               Robert E. Jensen   UGO1 Encodes an Outer Membrane Protein
                                  Required for Mitochondrial Fusion  . . . 1123
          Matthew K. Topham and   
            Stephen M. Prescott   Diacylglycerol Kinase $ \zeta $
                                  Regulates Ras Activation by a Novel
                                  Mechanism  . . . . . . . . . . . . . . . 1135
        Lars Kjòller and   
                      Alan Hall   Rac Mediates Cytoskeletal Rearrangements
                                  and Increased Cell Motility Induced by
                                  Urokinase--Type Plasminogen Activator
                                  Receptor Binding to Vitronectin  . . . . 1145
         Clarissa L. Waites and   
                Anand Mehta and   
              Philip K. Tan and   
                Gary Thomas and   
          Robert H. Edwards and   
                David E. Krantz   An Acidic Motif Retains Vesicular
                                  Monoamine Transporter 2 on Large Dense
                                  Core Vesicles  . . . . . . . . . . . . . 1159
         Josephine C. Adams and   
              Nina Kureishy and   
               Amanda L. Taylor   A Role for Syndecan-1 in Coupling Fascin
                                  Spike Formation by Thrombospondin-1  . . 1169
             Atsushi Suzuki and   
          Tomoyuki Yamanaka and   
            Tomonori Hirose and   
             Naoyuki Manabe and   
               Keiko Mizuno and   
               Miki Shimizu and   
           Kazunori Akimoto and   
              Yasushi Izumi and   
             Tetsuo Ohnishi and   
                    Shigeo Ohno   Atypical Protein Kinase C Is Involved in
                                  the Evolutionarily Conserved Par Protein
                                  Complex and Plays a Critical Role in
                                  Establishing Epithelia--Specific
                                  Junctional Structures  . . . . . . . . . 1183
            Bernard Degryse and   
            Tiziana Bonaldi and   
             Paola Scaffidi and   
        Susanne Müller and   
            Massimo Resnati and   
          Francesca Sanvito and   
         Gianluigi Arrigoni and   
               Marco E. Bianchi   The High Mobility Group (Hmg) Boxes of
                                  the Nuclear Protein Hmg1 Induce
                                  Chemotaxis and Cytoskeleton
                                  Reorganization in Rat Smooth Muscle
                                  Cells  . . . . . . . . . . . . . . . . . 1197
             Dean J. Burkin and   
         Gregory Q. Wallace and   
          Kimberly J. Nicol and   
           David J. Kaufman and   
             Stephen J. Kaufman   Enhanced Expression of the $ \alpha $7$
                                  \beta $1 Integrin Reduces Muscular
                                  Dystrophy and Restores Viability in
                                  Dystrophic Mice  . . . . . . . . . . . . 1207
            Brian D. Ackley and   
           Jennifer R. Crew and   
               Harri Elamaa and   
         Tania Pihlajaniemi and   
              Calvin J. Kuo and   
                James M. Kramer   The Nc1/Endostatin Domain of
                                  \bionameCaenorhabditis elegans Type
                                  XVIII Collagen Affects Cell Migration
                                  and Axon Guidance  . . . . . . . . . . . 1219
              Calvin J. Kuo and   
      Kenneth R. LaMontagne and   
Guillermo Garcia-Cardeña and   
            Brian D. Ackley and   
              Daniel Kalman and   
                 Susan Park and   
        Rolf Christofferson and   
             Junne Kamihara and   
              Yuan-Hua Ding and   
                Kin-Ming Lo and   
            Stephen Gillies and   
              Judah Folkman and   
        Richard C. Mulligan and   
               Kashi Javaherian   Oligomerization-Dependent Regulation of
                                  Motility and Morphogenesis by the
                                  Collagen XVIII Nc1/Endostatin Domain . . 1233
          Boris Troyanovsky and   
          Tetyana Levchenko and   
   Göran Månsson and   
            Olga Matvijenko and   
                  Lars Holmgren   Angiomotin . . . . . . . . . . . . . . . 1247
            Chad G. Pearson and   
             Paul S. Maddox and   
               E. D. Salmon and   
                    Kerry Bloom   Budding Yeast Chromosome Structure and
                                  Dynamics during Mitosis  . . . . . . . . 1255
          Laura Furstenthal and   
            Brett K. Kaiser and   
              Craig Swanson and   
               Peter K. Jackson   Cyclin E Uses Cdc6 as a
                                  Chromatin--Associated Receptor Required
                                  for DNA Replication  . . . . . . . . . . 1267
                  Yi-Tao Yu and   
                 Mei-Di Shu and   
           Aarthi Narayanan and   
           Rebecca M. Terns and   
           Michael P. Terns and   
                 Joan A. Steitz   Internal Modification of U2 Small
                                  Nuclear (Snrna) Occurs in Nucleoli of
                                  \bionameXenopus Oocytes  . . . . . . . . 1279
             George Zanazzi and   
            Steven Einheber and   
          Richard Westreich and   
      Melanie-Jane Hannocks and   
         Debra Bedell-Hogan and   
         Mark A. Marchionni and   
                James L. Salzer   Glial Growth Factor/Neuregulin Inhibits
                                  Schwann Cell Myelination and Induces
                                  Demyelination  . . . . . . . . . . . . . 1289
            Yuri V. Fedorov and   
         R. Scott Rosenthal and   
               Bradley B. Olwin   Oncogenic Ras--Induced Proliferation
                                  Requires Autocrine Fibroblast Growth
                                  Factor 2 Signaling in Skeletal Muscle
                                  Cells  . . . . . . . . . . . . . . . . . 1301
             John F. Reilly and   
                Pamela A. Maher   Importin $ \beta $--Mediated Nuclear
                                  Import of Fibroblast Growth Factor
                                  Receptor . . . . . . . . . . . . . . . . 1307
                  Shoichiro Ono   The \bionameCaenorhabditis elegans
                                  unc-78 Gene Encodes a Homologue of
                                  Actin--Interacting Protein 1 Required
                                  for Organized Assembly of Muscle Actin
                                  Filaments  . . . . . . . . . . . . . . . 1313


Journal of Cell Biology
Volume 153, Number 1, April, 2001

     Lúcia S. Borges and   
                  Michael Ferns   Agrin-Induced Phosphorylation of the
                                  Acetylcholine Receptor Regulates
                                  Cytoskeletal Anchoring and Clustering    1
               Carlo Iomini and   
    Veronica Babaev-Khaimov and   
          Massimo Sassaroli and   
                 Gianni Piperno   Protein Particles in Chlamydomonas
                                  Flagella Undergo a Transport Cycle
                                  Consisting of Four Phases  . . . . . . . 13
                Wanjoo Chun and   
             Mathieu Lesort and   
           Janusz Tucholski and   
        Christopher A. Ross and   
             Gail V. W. Johnson   Tissue Transglutaminase Does Not
                                  Contribute to the Formation of Mutant
                                  Huntingtin Aggregates  . . . . . . . . . 25
                  Xiao Yang and   
                   Lin Chen and   
                Xiaoling Xu and   
                 Cuiling Li and   
               Cuifen Huang and   
                   Chu-Xia Deng   TGF-$ \beta $ \slash Smad3 Signals
                                  Repress Chondrocyte Hypertrophic
                                  Differentiation and Are Required for
                                  Maintaining Articular Cartilage  . . . . 35
        Olivia W. Rossanese and   
        Catherine A. Reinke and   
            Brooke J. Bevis and   
            Adam T. Hammond and   
             Irina B. Sears and   
             James O'Connor and   
              Benjamin S. Glick   A Role for Actin, Cdc1p, and Myo2p in
                                  the Inheritance of Late Golgi Elements
                                  in \bionameSaccharomyces cerevisiae  . . 47
         Carolyn D. Silflow and   
             Matthew LaVoie and   
                 Lai-Wa Tam and   
               Susan Tousey and   
               Mark Sanders and   
               Wei-chien Wu and   
            Mark Borodovsky and   
               Paul A. Lefebvre   The Vfl1 Protein in Chlamydomonas
                                  Localizes in a Rotationally Asymmetric
                                  Pattern at the Distal Ends of the Basal
                                  Bodies . . . . . . . . . . . . . . . . . 63
           Vitold E. Galkin and   
              Albina Orlova and   
         Natalya Lukoyanova and   
             Willy Wriggers and   
              Edward H. Egelman   Actin Depolymerizing Factor Stabilizes
                                  an Existing State of F--Actin and Can
                                  Change the Tilt of F--Actin Subunits . . 75
               Chisato Ueta and   
           Masahiro Iwamoto and   
             Naoko Kanatani and   
           Carolina Yoshida and   
                   Yang Liu and   
     Motomi Enomoto-Iwamoto and   
            Tomoharu Ohmori and   
           Hirayuki Enomoto and   
                 Ken Nakata and   
               Kenji Takada and   
              Kojiro Kurisu and   
               Toshihisa Komori   Skeletal Malformations Caused by
                                  Overexpression of Cbfa1 or Its Dominant
                                  Negative Form in Chondrocytes  . . . . . 87
                 Kami Ahmad and   
                Steven Henikoff   Centromeres Are Specialized Replication
                                  Domains in Heterochromatin . . . . . . . 101
            Stanislav Vitha and   
       Rosemary S. McAndrew and   
        Katherine W. Osteryoung   Ftsz Ring Formation at the Chloroplast
                                  Division Site in Plants  . . . . . . . . 111
           Nicole den Elzen and   
                 Jonathon Pines   Cyclin a Is Destroyed in Prometaphase
                                  and Can Delay Chromosome Alignment and
                                  Anaphase . . . . . . . . . . . . . . . . 121
              Stephan Geley and   
               Edgar Kramer and   
         Christian Gieffers and   
              Julian Gannon and   
         Jan-Michael Peters and   
                       Tim Hunt   Anaphase-Promoting
                                  Complex/Cyclosome-Dependent Proteolysis
                                  of Human Cyclin a Starts at the
                                  Beginning of Mitosis and Is Not Subject
                                  to the Spindle Assembly Checkpoint . . . 137
        Priya Prakash Budde and   
              Akiko Kumagai and   
          William G. Dunphy and   
                  Rebecca Heald   Regulation of Op18 during Spindle
                                  Assembly in \bionameXenopus Egg Extracts 149
             Neil R. Adames and   
          Jessica R. Oberle and   
                 John A. Cooper   The Surveillance Mechanism of the
                                  Spindle Position Checkpoint in Yeast . . 159
               Danyang Chen and   
                      Sui Huang   Nucleolar Components Involved in
                                  Ribosome Biogenesis Cycle between the
                                  Nucleolus and Nucleoplasm in Interphase
                                  Cells  . . . . . . . . . . . . . . . . . 169
             Laura M. Johns and   
           Edwin S. Levitan and   
            Eric A. Shelden and   
             Ronald W. Holz and   
                 Daniel Axelrod   Restriction of Secretory Granule Motion
                                  near the Plasma Membrane of Chromaffin
                                  Cells  . . . . . . . . . . . . . . . . . 177
               David Reczek and   
              Anthony Bretscher   Identification of Epi64, a Tbc/Rabgap
                                  Domain--Containing Microvillar Protein
                                  That Binds to the First PDZ Domain of
                                  Ebp50 and E3karp . . . . . . . . . . . . 191
Miguel Angel Sanjuán and   
             David R. Jones and   
           Manuel Izquierdo and   
           Isabel Mérida   Role of Diacylglycerol Kinase $ \alpha $
                                  in the Attenuation of Receptor Signaling 207
          Darren L. Roberts and   
             Wendy Merrison and   
          Marion MacFarlane and   
                Gerald M. Cohen   The Inhibitor of Apoptosis
                                  Protein--Binding Domain of Smac Is Not
                                  Essential for Its Proapoptotic Activity  221
     Piergiorgio Percipalle and   
                  Jian Zhao and   
                 Brian Pope and   
                 Alan Weeds and   
               Uno Lindberg and   
                Bertil Daneholt   Actin Bound to the Heterogeneous Nuclear
                                  Ribonucleoprotein Hrp36 Is Associated
                                  with Balbiani Ring mRNA from the Gene to
                                  Polysomes  . . . . . . . . . . . . . . . 229
           Alexey Khodjakov and   
                Conly L. Rieder   Centrosomes Enhance the Fidelity of
                                  Cytokinesis in Vertebrates and Are
                                  Required for Cell Cycle Progression  . . 237

Journal of Cell Biology
Volume 153, Number 2, April, 2001

                T. J. Mitchison   Psychosine, Cytokinesis, and Orphan
                                  Receptors  . . . . . . . . . . . . . . . 0
             Peter M. Elias and   
        Norihisa Matsuyoshi and   
                    Hong Wu and   
                Chenyan Lin and   
              Zhi Hong Wang and   
           Barbara E. Brown and   
                John R. Stanley   Desmoglein Isoform Distribution Affects
                                  Stratum Corneum Structure and Function   243
         Nima Mosammaparast and   
          Kelley R. Jackson and   
                 Yurong Guo and   
           Cynthia J. Brame and   
        Jeffrey Shabanowitz and   
             Donald F. Hunt and   
              Lucy F. Pemberton   Nuclear Import of Histone H2a and H2b Is
                                  Mediated by a Network of Karyopherins    251
               Mikio Furuse and   
               Kyoko Furuse and   
            Hiroyuki Sasaki and   
              Shoichiro Tsukita   Conversion of Zonulae Occludentes from
                                  Tight to Leaky Strand Type by
                                  Introducing Claudin-2 into Madin--Darby
                                  Canine Kidney I Cells  . . . . . . . . . 263
            Andrew E. Aplin and   
          Sheryl A. Stewart and   
         Richard K. Assoian and   
                  R. L. Juliano   Integrin-Mediated Adhesion Regulates ERK
                                  Nuclear Translocation and
                                  Phosphorylation of Elk-1 . . . . . . . . 273
             Steven T. Suhr and   
         Marie-Claude Senut and   
       Julian P. Whitelegge and   
               Kym F. Faull and   
           Denise B. Cuizon and   
                   Fred H. Gage   Identities of Sequestered Proteins in
                                  Aggregates from Cells with Induced
                                  Polyglutamine Expression . . . . . . . . 283
   Seema K. Tiwari-Woodruff and   
           Alex G. Buznikov and   
                Trung Q. Vu and   
           Paul E. Micevych and   
               Kendall Chen and   
         Harley I. Kornblum and   
              Jeff M. Bronstein   Osp\slash Claudin-11 Forms a Complex
                                  with a Novel Member of the Tetraspanin
                                  Super Family and $ \beta $1 Integrin and
                                  Regulates Proliferation and Migration of
                                  Oligodendrocytes . . . . . . . . . . . . 295
                Roy M. Long and   
                     Wei Gu and   
                Xiuhua Meng and   
          Graydon Gonsalvez and   
           Robert H. Singer and   
               Pascal Chartrand   An Exclusively Nuclear RNA--Binding
                                  Protein Affects Asymmetric Localization
                                  of ASH1 mRNA and Ash1p in Yeast  . . . . 307
        Nigel J. Waterhouse and   
        Joshua C. Goldstein and   
           Oliver von Ahsen and   
             Martin Schuler and   
         Donald D. Newmeyer and   
               Douglas R. Green   Cytochrome C Maintains Mitochondrial
                                  Transmembrane Potential and ATP
                                  Generation after Outer Mitochondrial
                                  Membrane Permeabilization during the
                                  Apoptotic Process  . . . . . . . . . . . 319
            Valerie Horsley and   
             Bret B. Friday and   
             Sarah Matteson and   
       Kristy Miller Kegley and   
           Jonathan Gephart and   
               Grace K. Pavlath   Regulation of the Growth of
                                  Multinucleated Muscle Cells by an
                                  Nfatc2-Dependent Pathway . . . . . . . . 329
           Sahar F. Mahmoud and   
                 Clare Fewtrell   Microdomains of High Calcium Are Not
                                  Required for Exocytosis in Rbl-2h3
                                  Mucosal Mast Cells . . . . . . . . . . . 339
         Michael M. Kessels and   
Åsa E. Y. Engqvist-Goldstein and   
            David G. Drubin and   
                Britta Qualmann   Mammalian Abp1, a Signal--Responsive
                                  F--Actin--Binding Protein, Links the
                                  Actin Cytoskeleton to Endocytosis via
                                  the Gtpase Dynamin . . . . . . . . . . . 351
             Oliver Bischof and   
                Sahn-Ho Kim and   
                John Irving and   
            Sergey Beresten and   
            Nathan A. Ellis and   
                 Judith Campisi   Regulation and Localization of the Bloom
                                  Syndrome Protein in Response to DNA
                                  Damage . . . . . . . . . . . . . . . . . 367
                   John Kim and   
            Yoshiaki Kamada and   
           Per E. Stromhaug and   
                    Ju Guan and   
         Ann Hefner-Gravink and   
                Misuzu Baba and   
            Sidney V. Scott and   
           Yoshinori Ohsumi and   
            William A. Dunn and   
             Daniel J. Klionsky   Cvt9\slash Gsa9 Functions in
                                  Sequestering Selective Cytosolic Cargo
                                  Destined for the Vacuole . . . . . . . . 381
                 P. T. Tran and   
                   L. Marsh and   
                    V. Doye and   
            S. Inoué and   
                       F. Chang   A Mechanism for Nuclear Positioning in
                                  Fission Yeast Based on Microtubule
                                  Pushing  . . . . . . . . . . . . . . . . 397
          Marie-Louise Bang and   
              Ryan E. Mudry and   
       Abigail S. McElhinny and   
    Karoly Trombitás and   
              Adam J. Geach and   
               Rob Yamasaki and   
         Hiroyuki Sorimachi and   
              Henk Granzier and   
          Carol C. Gregorio and   
               Siegfried Labeit   Myopalladin, a Novel 145-Kilodalton
                                  Sarcomeric Protein with Multiple Roles
                                  in Z--Disc and I--Band Protein
                                  Assemblies . . . . . . . . . . . . . . . 413
               Dong-Soon Im and   
       Christopher E. Heise and   
                Tuan Nguyen and   
            Brian F. O'Dowd and   
                 Kevin R. Lynch   Identification of a Molecular Target of
                                  Psychosine and Its Role in Globoid Cell
                                  Formation  . . . . . . . . . . . . . . . 429
              Fedor Severin and   
           Bianca Habermann and   
               Tim Huffaker and   
                     Tony Hyman   Stu2 Promotes Mitotic Spindle Elongation
                                  in Anaphase  . . . . . . . . . . . . . . 435
        Anne Roush Gaillard and   
           Dennis R. Diener and   
          Joel L. Rosenbaum and   
               Winfield S. Sale   Flagellar Radial Spoke Protein 3 Is an
                                  a--Kinase Anchoring Protein (Akap) . . . 443

Journal of Cell Biology
Volume 153, Number 3, April, 2001

                    Brian Burke   Lamins and Apoptosis . . . . . . . . . . 0
             Colin M. Heath and   
             Miriam Windsor and   
                 Thomas Wileman   Aggresomes Resemble Sites Specialized
                                  for Virus Assembly . . . . . . . . . . . 449
                Jin Woo Kim and   
            Tong-Shin Chang and   
                 Ji Eun Lee and   
                Sung-Ho Huh and   
             Seung Woo Yeon and   
              Wan Seok Yang and   
               Cheol O. Joe and   
            Inhee Mook-Jung and   
           Rudolph E. Tanzi and   
                Tae-Wan Kim and   
                    Eui-Ju Choi   Negative Regulation of the Sapk/Jnk
                                  Signaling Pathway by Presenilin 1  . . . 457
           Edith Hintermann and   
              Martin Bilban and   
             Andrew Sharabi and   
                  Vito Quaranta   Inhibitory Role of $ \alpha $6$ \beta
                                  $4-Associated Erbb-2 and
                                  Phosphoinositide 3-Kinase in
                                  Keratinocyte Haptotactic Migration
                                  Dependent on $ \alpha $3$ \beta $1
                                  Integrin . . . . . . . . . . . . . . . . 465
           Eric C. Schirmer and   
                Tinglu Guan and   
                   Larry Gerace   Involvement of the Lamin Rod Domain in
                                  Heterotypic Lamin Interactions Important
                                  for Nuclear Organization . . . . . . . . 479
                 Laurie Erb and   
                    Jun Liu and   
       Jonathan Ockerhausen and   
              Qiongman Kong and   
          Richard C. Garrad and   
              Korey Griffin and   
                 Chris Neal and   
                Brent Krugh and   
Laura I. Santiago-Pérez and   
Fernando A. González and   
          Hattie D. Gresham and   
             John T. Turner and   
                Gary A. Weisman   An Rgd Sequence in the P2y$_2$ Receptor
                                  Interacts with $ \alpha_V \beta_3 $
                                  Integrins and Is Required for
                                  G$_o$-Mediated Signal Transduction . . . 491
            Kyeong Han Yoon and   
                  Miri Yoon and   
             Robert D. Moir and   
                Satya Khuon and   
       Frederick W. Flitney and   
              Robert D. Goldman   Insights into the Dynamic Properties of
                                  Keratin Intermediate Filaments in Living
                                  Epithelial Cells . . . . . . . . . . . . 503
             Daniela Cimini and   
              Bonnie Howell and   
                Paul Maddox and   
           Alexey Khodjakov and   
         Francesca Degrassi and   
                   E. D. Salmon   Merotelic Kinetochore Orientation Is a
                                  Major Mechanism of Aneuploidy in Mitotic
                                  Mammalian Tissue Cells . . . . . . . . . 517
        Benjamin J. Nichols and   
          Anne K. Kenworthy and   
        Roman S. Polishchuk and   
               Robert Lodge and   
         Theresa H. Roberts and   
           Koret Hirschberg and   
            Robert D. Phair and   
   Jennifer Lippincott-Schwartz   Rapid Cycling of Lipid Raft Markers
                                  between the Cell Surface and Golgi
                                  Complex  . . . . . . . . . . . . . . . . 529
        Mats Hellström and   
            Holger Gerhardt and   
       Mattias Kalén and   
                    Xuri Li and   
               Ulf Eriksson and   
            Hartwig Wolburg and   
             Christer Betsholtz   Lack of Pericytes Leads to Endothelial
                                  Hyperplasia and Abnormal Vascular
                                  Morphogenesis  . . . . . . . . . . . . . 543
           Alexandra Imbert and   
             Rachel Eelkema and   
                Sara Jordan and   
               Helen Feiner and   
                   Pamela Cowin   $ \Delta $n89$ \beta $-Catenin Induces
                                  Precocious Development, Differentiation,
                                  and Neoplasia in Mammary Gland . . . . . 555
                Kazuo Katoh and   
                Yumiko Kano and   
              Mutsuki Amano and   
            Hirofumi Onishi and   
              Kozo Kaibuchi and   
                 Keigi Fujiwara   Rho-Kinase--Mediated Contraction of
                                  Isolated Stress Fibers . . . . . . . . . 569
                  Yizeng Tu and   
                  Yao Huang and   
              Yongjun Zhang and   
                    Yun Hua and   
                    Chuanyue Wu   A New Focal Adhesion Protein That
                                  Interacts with Integrin--Linked Kinase
                                  and Regulates Cell Adhesion and
                                  Spreading  . . . . . . . . . . . . . . . 585
               Miho Matsuda and   
           Hugh F. Paterson and   
            Rosie Rodriguez and   
          Amanda C. Fensome and   
             Moira V. Ellis and   
                 Karl Swann and   
                  Matilda Katan   Real Time Fluorescence Imaging of Plc$
                                  \gamma $ Translocation and Its
                                  Interaction with the Epidermal Growth
                                  Factor Receptor  . . . . . . . . . . . . 599
              Irene Rappold and   
         Kuniyoshi Iwabuchi and   
              Takayasu Date and   
                    Junjie Chen   Tumor Suppressor P53 Binding Protein 1
                                  (53bp1) Is Involved in DNA
                                  Damage--Signaling Pathways . . . . . . . 613
             Rikke L. Steen and   
                Philippe Collas   Mistargeting of B--Type Lamins at the
                                  End of Mitosis . . . . . . . . . . . . . 621
             Bruce L. Goode and   
            Avital A. Rodal and   
            Georjana Barnes and   
                David G. Drubin   Activation of the Arp2/3 Complex by the
                                  Actin Filament Binding Protein Abp1p . . 627

Journal of Cell Biology
Volume 153, Number 4, May, 2001

                   Ellis Cooper   A New Role for Ion Channels in Myoblast
                                  Fusion . . . . . . . . . . . . . . . . . 0
              Richard J. Maraia   La Protein and the Trafficking of
                                  Nascent RNA Polymerase III Transcripts   ??
         James G. Wakefield and   
          Silvia Bonaccorsi and   
                 Maurizio Gatti   The \bionameDrosophila Protein Asp Is
                                  Involved in Microtubule Organization
                                  during Spindle Formation and Cytokinesis 637
       Stephen B. Helliwell and   
               Sascha Losko and   
                Chris A. Kaiser   Components of a Ubiquitin Ligase Complex
                                  Specify Polyubiquitination and
                                  Intracellular Trafficking of the General
                                  Amino Acid Permease  . . . . . . . . . . 649
          Mary M. Donaldson and   
Álvaro A. M. Tavares and   
            Hiroyuki Ohkura and   
                 Peter Deak and   
                David M. Glover   Metaphase Arrest with Centromere
                                  Separation in polo Mutants of
                                  \bionameDrosophila . . . . . . . . . . . 663
Jacqueline Fischer-Lougheed and   
               Jian-Hui Liu and   
            Estelle Espinos and   
            David Mordasini and   
           Charles R. Bader and   
            Dominique Belin and   
               Laurent Bernheim   Human Myoblast Fusion Requires
                                  Expression of Functional Inward
                                  Rectifier Kir2.1 Channels  . . . . . . . 677
             Koshiro Monzen and   
                Yukio Hiroi and   
               Sumiyo Kudoh and   
            Hiroshi Akazawa and   
                   Toru Oka and   
              Eiki Takimoto and   
             Doubun Hayashi and   
                Toru Hosoda and   
          Masahiro Kawabata and   
             Kohei Miyazono and   
             Shunsuke Ishii and   
              Yoshio Yazaki and   
                Ryozo Nagai and   
                   Issei Komuro   Smads, Tak1, and Their Common Target
                                  Atf-2 Play a Critical Role in
                                  Cardiomyocyte Differentiation  . . . . . 687
             Steven O. Marx and   
              Steven Reiken and   
             Yuji Hisamatsu and   
          Marta Gaburjakova and   
           Jana Gaburjakova and   
               Yi-Ming Yang and   
             Nora Rosemblit and   
                Andrew R. Marks   Phosphorylation-Dependent Regulation of
                                  Ryanodine Receptors  . . . . . . . . . . 699
           Marcello Marelli and   
            C. Patrick Lusk and   
                 Honey Chan and   
          John D. Aitchison and   
             Richard W. Wozniak   A Link between the Synthesis of
                                  Nucleoporins and the Biogenesis of the
                                  Nuclear Envelope . . . . . . . . . . . . 709
         Kawther Abu-Elneel and   
        Derrick R. Robinson and   
               Mark E. Drew and   
            Paul T. Englund and   
                 Joseph Shlomai   Intramitochondrial Localization of
                                  Universal Minicircle Sequence--Binding
                                  Protein, a Trypanosomatid Protein That
                                  Binds Kinetoplast Minicircle Replication
                                  Origins  . . . . . . . . . . . . . . . . 725
               Mark E. Drew and   
                Paul T. Englund   Intramitochondrial Location and Dynamics
                                  of Crithidia fasciculata Kinetoplast
                                  Minicircle Replication Intermediates . . 735
            Helge Grosshans and   
             Karina Deinert and   
                    Ed Hurt and   
                   George Simos   Biogenesis of the Signal Recognition
                                  Particle (Srp) Involves Import of Srp
                                  Proteins into the Nucleolus, Assembly
                                  with the Srp--RNA, and Xpo1p-Mediated
                                  Export . . . . . . . . . . . . . . . . . 745
            Elisabeth Ehler and   
            Robert Horowits and   
        Christian Zuppinger and   
            Robert L. Price and   
           Evelyne Perriard and   
                 Martin Leu and   
                Pico Caroni and   
               Mark Sussman and   
        Hans M. Eppenberger and   
           Jean-Claude Perriard   Alterations at the Intercalated Disk
                                  Associated with the Absence of Muscle
                                  Lim Protein  . . . . . . . . . . . . . . 763
   Györgyi Csankovszki and   
         András Nagy and   
                Rudolf Jaenisch   Synergism of Xist RNA, DNA Methylation,
                                  and Histone Hypoacetylation in
                                  Maintaining X Chromosome Inactivation    773
                Yohei Hirai and   
              Derek Radisky and   
           Rosanne Boudreau and   
              Marina Simian and   
            Mary E. Stevens and   
                 Yumiko Oka and   
               Kyoko Takebe and   
            Shinichiro Niwa and   
                Mina J. Bissell   Epimorphin Mediates Mammary Luminal
                                  Morphogenesis through Control of C/EBP$
                                  \beta $  . . . . . . . . . . . . . . . . 785
            Satoru Funamoto and   
             Kristina Milan and   
                Ruedi Meili and   
              Richard A. Firtel   Role of Phosphatidylinositol 3' Kinase
                                  and a Downstream Pleckstrin Homology
                                  Domain--Containing Protein in
                                  Controlling Chemotaxis in
                                  \bionameDictyostelium  . . . . . . . . . 795
                Xiaofeng Li and   
                  Yali Chen and   
     Susanne Schéele and   
               Esther Arman and   
     Rebecca Haffner-Krausz and   
               Peter Ekblom and   
                    Peter Lonai   Fibroblast Growth Factor Signaling and
                                  Basement Membrane Assembly Are Connected
                                  during Epithelial Morphogenesis of the
                                  Embryoid Body  . . . . . . . . . . . . . 811
             Reto Caldelari and   
             Alain de Bruin and   
          Dominique Baumann and   
              Maja M. Suter and   
        Christiane Bierkamp and   
               Vreni Balmer and   
             Eliane Müller   A Central Role for the Armadillo Protein
                                  Plakoglobin in the Autoimmune Disease
                                  Pemphigus Vulgaris . . . . . . . . . . . 823
   Laurent Gagnoux-Palacios and   
           Maryline Allegra and   
             Flavia Spirito and   
           Olivier Pommeret and   
           Christine Romero and   
          Jean-paul Ortonne and   
             Guerrino Meneguzzi   The Short Arm of the Laminin $ \gamma $2
                                  Chain Plays a Pivotal Role in the
                                  Incorporation of Laminin 5 into the
                                  Extracellular Matrix and in Cell
                                  Adhesion . . . . . . . . . . . . . . . . 835
          Anatoli B. Meriin and   
          Katsuhide Mabuchi and   
          Vladimir L. Gabai and   
            Julia A. Yaglom and   
             Alex Kazantsev and   
             Michael Y. Sherman   Intracellular Aggregation of
                                  Polypeptides with Expanded Polyglutamine
                                  Domain Is Stimulated by
                                  Stress--Activated Kinase Mekk1 . . . . . 851
           Richard R. Adams and   
              Helder Maiato and   
        William C. Earnshaw and   
                    Mar Carmena   Essential Roles of \bionameDrosophila
                                  Inner Centromere Protein (Incenp) and
                                  Aurora B in Histone H3 Phosphorylation,
                                  Metaphase Chromosome Alignment,
                                  Kinetochore Disjunction, and Chromosome
                                  Segregation  . . . . . . . . . . . . . . 865
           Karen A. Beningo and   
                Micah Dembo and   
             Irina Kaverina and   
            J. Victor Small and   
                     Yu-li Wang   Nascent Focal Adhesions Are Responsible
                                  for the Generation of Strong Propulsive
                                  Forces in Migrating Fibroblasts  . . . . 881

Journal of Cell Biology
Volume 153, Number 5, May, 2001

              Susumu Tomita and   
            Roger A. Nicoll and   
                 David S. Bredt   PDZ Protein Interactions Regulating
                                  Glutamate Receptor Function and
                                  Plasticity . . . . . . . . . . . . . . . 0
            Masahiro Kajita and   
             Yoshifumi Itoh and   
            Tadashige Chiba and   
             Hidetoshi Mori and   
                Akiko Okada and   
              Hiroaki Kinoh and   
                 Motoharu Seiki   Membrane-Type 1 Matrix Metalloproteinase
                                  Cleaves Cd44 and Promotes Cell Migration 893
             Erkki Koivunen and   
          Tanja-Maria Ranta and   
                Arto Annila and   
                Seija Taube and   
                Asko Uppala and   
           Marjukka Jokinen and   
      Gijsbert van Willigen and   
            Eveliina Ihanus and   
               Carl G. Gahmberg   Inhibition of $ \beta_2 $
                                  Integrin-Mediated Leukocyte Cell
                                  Adhesion by Leucine--Leucine--Glycine
                                  Motif-Containing Peptides  . . . . . . . 905
         Rebecca S. Muraoka and   
       Anne E. G. Lenferink and   
               Jean Simpson and   
           Dana M. Brantley and   
           L. Renee Roebuck and   
           F. Michael Yakes and   
              Carlos L. Arteaga   Cyclin-Dependent Kinase Inhibitor
                                  P27$^{\rm Kip1}$ Is Required for Mouse
                                  Mammary Gland Morphogenesis and Function 917
               Michael Sixt and   
          Britta Engelhardt and   
          Friederike Pausch and   
            Rupert Hallmann and   
               Olaf Wendler and   
               Lydia M. Sorokin   Endothelial Cell Laminin Isoforms,
                                  Laminins 8 and 10, Play Decisive Roles
                                  in T Cell Recruitment across the
                                  Blood--Brain Barrier in Experimental
                                  Autoimmune Encephalomyelitis . . . . . . 933
             Niels Volkmann and   
             David DeRosier and   
            Paul Matsudaira and   
                   Dorit Hanein   An Atomic Model of Actin Filaments
                                  Cross--Linked by Fimbrin and Its
                                  Implications for Bundle Assembly and
                                  Function . . . . . . . . . . . . . . . . 947
         Mohamed Benharouga and   
              Martin Haardt and   
            Norbert Kartner and   
              Gergely L. Lukacs   Cooh-Terminal Truncations Promote
                                  Proteasome--Dependent Degradation of
                                  Mature Cystic Fibrosis Transmembrane
                                  Conductance Regulator from post-Golgi
                                  Compartments . . . . . . . . . . . . . . 957
                E. Bonnelye and   
                  L. Merdad and   
                    V. Kung and   
                    J. E. Aubin   The Orphan Nuclear Estrogen
                                  Receptor--Related Receptor $ \alpha $
                                  (Err$ \alpha $) Is Expressed Throughout
                                  Osteoblast Differentiation and Regulates
                                  Bone Formation in Vitro  . . . . . . . . 971
               Steve Palmer and   
              Nicola Groves and   
           Aaron Schindeler and   
                Thomas Yeoh and   
            Christine Biben and   
            Cheng-Chun Wang and   
          Duncan B. Sparrow and   
             Louise Barnett and   
           Nancy A. Jenkins and   
           Neal G. Copeland and   
             Frank Koentgen and   
                  Tim Mohun and   
              Richard P. Harvey   The Small Muscle--Specific Protein Csl
                                  Modifies Cell Shape and Promotes Myocyte
                                  Fusion in an Insulin-like Growth Factor
                                  1--Dependent Manner  . . . . . . . . . . 985
           Lasse Foghsgaard and   
              Dorte Wissing and   
               Daniel Mauch and   
             Ulrik Lademann and   
              Lone Bastholm and   
              Marianne Boes and   
              Folmer Elling and   
               Marcel Leist and   
  Marja Jäättelä   Cathepsin B Acts as a Dominant Execution
                                  Protease in Tumor Cell Apoptosis Induced
                                  by Tumor Necrosis Factor . . . . . . . . 999
               Isabel Novoa and   
               Huiqing Zeng and   
         Heather P. Harding and   
                      David Ron   Feedback Inhibition of the Unfolded
                                  Protein Response by GADD34-Mediated
                                  Dephosphorylation of eIF2$ \alpha $  . . 1011
                  Rong Wang and   
           Linda D. Ferrell and   
              Saadia Faouzi and   
         Jacquelyn J. Maher and   
              J. Michael Bishop   Activation of the Met Receptor by Cell
                                  Attachment Induces and Sustains
                                  Hepatocellular Carcinomas in Transgenic
                                  Mice . . . . . . . . . . . . . . . . . . 1023
                 Partha Roy and   
               Zenon Rajfur and   
                David Jones and   
            Gerard Marriott and   
                Leslie Loew and   
                   Ken Jacobson   Local Photorelease of Caged Thymosin $
                                  \beta $4 in Locomoting Keratocytes
                                  Causes Cell Turning  . . . . . . . . . . 1035
           Cara J. Gottardi and   
                 Ellen Wong and   
              Barry M. Gumbiner   E-Cadherin Suppresses Cellular
                                  Transformation by Inhibiting $ \beta
                                  $-Catenin Signaling in an
                                  Adhesion--Independent Manner . . . . . . 1049
        Shuh-ichi Nishikawa and   
           Sheara W. Fewell and   
             Yoshihito Kato and   
         Jeffrey L. Brodsky and   
                   Toshiya Endo   Molecular Chaperones in the Yeast
                                  Endoplasmic Reticulum Maintain the
                                  Solubility of Proteins for
                                  Retrotranslocation and Degradation . . . 1061
             Feng-quan Zhou and   
           Christopher S. Cohan   Growth Cone Collapse through Coincident
                                  Loss of Actin Bundles and Leading Edge
                                  Actin without Actin Depolymerization . . 1071
                Marc Preuss and   
             Klaus Leonhard and   
                   Kai Hell and   
         Rosemary A. Stuart and   
             Walter Neupert and   
           Johannes M. Herrmann   Mba1, a Novel Component of the
                                  Mitochondrial Protein Export Machinery
                                  of the Yeast \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 1085
         Tulia Maria Savino and   
Jeannine Gébrane-Youn\`es and   
                 Jan De Mey and   
     Jean-Baptiste Sibarita and   
     Dani\`ele Hernandez-Verdun   Nucleolar Assembly of the Rrna
                                  Processing Machinery in Living Cells . . 1097
     José A. Martina and   
     Cecilia J. Bonangelino and   
    Rubén C. Aguilar and   
             Juan S. Bonifacino   Stonin 2 . . . . . . . . . . . . . . . . 1111
    Samara L. Reck-Peterson and   
           Matthew J. Tyska and   
            Peter J. Novick and   
               Mark S. Mooseker   The Yeast Class V Myosins, Myo2p and
                                  Myo4p, Are Nonprocessive Actin--Based
                                  Motors . . . . . . . . . . . . . . . . . 1121
            Laure Strochlic and   
              Annie Cartaud and   
       Valérie Labas and   
                Werner Hoch and   
               Jean Rossier and   
                   Jean Cartaud   Magi-1c  . . . . . . . . . . . . . . . . 1127
        Sergei A. Kuznetsov and   
          Mahesh H. Mankani and   
              Stan Gronthos and   
          Kazuhito Satomura and   
               Paolo Bianco and   
            Pamela Gehron Robey   Circulating Skeletal Stem Cells  . . . . 1133

Journal of Cell Biology
Volume 153, Number 6, June, 2001

            J. Richard McIntosh   Electron Microscopy of Cells . . . . . . 0
               Abby F. Dernburg   Here, There, and Everywhere  . . . . . . ??
             Jacob M. Jones and   
           James C. Morrell and   
               Stephen J. Gould   Multiple Distinct Targeting Signals in
                                  Integral Peroxisomal Membrane Proteins   1141
                 Uwe Ahting and   
            Michel Thieffry and   
          Harald Engelhardt and   
              Reiner Hegerl and   
             Walter Neupert and   
             Stephan Nussberger   Tom40, the Pore--Forming Component of
                                  the Protein--Conducting Tom Channel in
                                  the Outer Membrane of Mitochondria . . . 1151
              Sujata Persad and   
       Armelle A. Troussard and   
          Timothy R. McPhee and   
        David J. Mulholland and   
                 Shoukat Dedhar   Tumor Suppressor Pten Inhibits Nuclear
                                  Accumulation of $ \beta $-Catenin and T
                                  Cell/Lymphoid Enhancer Factor 1-Mediated
                                  Transcriptional Activation . . . . . . . 1161
            Daniel Riveline and   
                  Eli Zamir and   
        Nathalie Q. Balaban and   
          Ulrich S. Schwarz and   
         Toshimasa Ishizaki and   
              Shuh Narumiya and   
                    Zvi Kam and   
            Benjamin Geiger and   
        Alexander D. Bershadsky   Focal Contacts as Mechanosensors . . . . 1175
              Bao-yan Zhang and   
                  Amy Chang and   
         Thomas B. Kjeldsen and   
                    Peter Arvan   Intracellular Retention of Newly
                                  Synthesized Insulin in Yeast Is Caused
                                  by Endoproteolytic Processing in the
                                  Golgi Complex  . . . . . . . . . . . . . 1187
            Landon L. Moore and   
                   Mark B. Roth   Hcp-4, a Cenp--C-like Protein in
                                  \bionameCaenorhabditis elegans, Is
                                  Required for Resolution of Sister
                                  Centromeres  . . . . . . . . . . . . . . 1199
               Karen Oegema and   
               Arshad Desai and   
               Sonja Rybina and   
            Matthew Kirkham and   
               Anthony A. Hyman   Functional Analysis of Kinetochore
                                  Assembly in \bionameCaenorhabditis
                                  elegans  . . . . . . . . . . . . . . . . 1209
                  Mary Howe and   
           Kent L. McDonald and   
         Donna G. Albertson and   
               Barbara J. Meyer   Him-10 Is Required for Kinetochore
                                  Structure and Function on
                                  \bionameCaenorhabditis elegans
                                  Holocentric Chromosomes  . . . . . . . . 1227
         Hilary Sharp-Baker and   
                  Rey-Huei Chen   Spindle Checkpoint Protein Bub1 Is
                                  Required for Kinetochore Localization of
                                  Mad1, Mad2, Bub3, and Cenp--E,
                                  Independently of Its Kinase Activity . . 1239
             Satoshi Yamaji and   
             Atsushi Suzuki and   
              Yuki Sugiyama and   
              Yu-ichi Koide and   
          Michihiko Yoshida and   
             Heiwa Kanamori and   
              Hiroshi Mohri and   
                Shigeo Ohno and   
           Yoshiaki Ishigatsubo   A Novel Integrin--Linked Kinase--Binding
                                  Protein, Affixin, Is Involved in the
                                  Early Stage of Cell--Substrate
                                  Interaction  . . . . . . . . . . . . . . 1251
           Amotz Nechushtan and   
           Carolyn L. Smith and   
         Itschak Lamensdorf and   
               Soo-Han Yoon and   
               Richard J. Youle   Bax and Bak Coalesce into Novel
                                  Mitochondria--Associated Clusters during
                                  Apoptosis  . . . . . . . . . . . . . . . 1265
       Charles J. Dimitroff and   
                Jack Y. Lee and   
               Shahin Rafii and   
       Robert C. Fuhlbrigge and   
               Robert Sackstein   Cd44 Is a Major E--Selectin Ligand on
                                  Human Hematopoietic Progenitor Cells . . 1277
     Dieter R. Klopfenstein and   
          Judith Klumperman and   
               Ariel Lustig and   
        Richard A. Kammerer and   
             Viola Oorschot and   
               Hans-Peter Hauri   Subdomain-Specific Localization of
                                  Climp-63 (P63) in the Endoplasmic
                                  Reticulum Is Mediated by Its Luminal $
                                  \alpha $-Helical Segment . . . . . . . . 1287
               Mounia Chami and   
            Devrim Gozuacik and   
              David Lagorce and   
               Marisa Brini and   
              Pierre Falson and   
  Gérard Peaucellier and   
               Paolo Pinton and   
       Hervé Lecoeur and   
         Marie-Lyse Gougeon and   
              Marc le Maire and   
            Rosario Rizzuto and   
   Christian Bréchot and   
Patrizia Paterlini-Bréchot   Serca1 Truncated Proteins Unable to Pump
                                  Calcium Reduce the Endoplasmic Reticulum
                                  Calcium Concentration and Induce
                                  Apoptosis  . . . . . . . . . . . . . . . 1301
                Pinfen Yang and   
           Dennis R. Diener and   
          Joel L. Rosenbaum and   
               Winfield S. Sale   Localization of Calmodulin and Dynein
                                  Light Chain Lc8 in Flagellar Radial
                                  Spokes . . . . . . . . . . . . . . . . . 1315
     Vladislav V. Speransky and   
         Kimberly L. Taylor and   
           Herman K. Edskes and   
            Reed B. Wickner and   
             Alasdair C. Steven   Prion Filament Networks in [Ure3] Cells
                                  of \bionameSaccharomyces cerevisiae  . . 1327

Journal of Cell Biology
Volume 153, Number 7, June, 2001

            Hiroki Hagiwara and   
               Justin R. Fallon   Shaping Membrane Architecture  . . . . . 0
             Hiroshi Kimura and   
                  Peter R. Cook   Kinetics of Core Histones in Living
                                  Human Cells  . . . . . . . . . . . . . . 1341
                Hyukjin Cha and   
                   Paul Shapiro   Tyrosine-Phosphorylated Extracellular
                                  Signal-Regulated Kinase Associates with
                                  the Golgi Complex during G2/M Phase of
                                  the Cell Cycle . . . . . . . . . . . . . 1355
           John G. Marshall and   
             James W. Booth and   
              Vuk Stambolic and   
                    Tak Mak and   
                Tamas Balla and   
          Alan D. Schreiber and   
               Tobias Meyer and   
               Sergio Grinstein   Restricted Accumulation of
                                  Phosphatidylinositol 3-Kinase Products
                                  in a Plasmalemmal Subdomain during Fc$
                                  \gamma $ Receptor-Mediated Phagocytosis  1369
          Andrea C. Carrano and   
                 Michele Pagano   Role of the F--Box Protein Skp2 in
                                  Adhesion--Dependent Cell Cycle
                                  Progression  . . . . . . . . . . . . . . 1381
            Mark E. Lindsay and   
           James M. Holaska and   
                Katie Welch and   
           Bryce M. Paschal and   
                  Ian G. Macara   Ran-Binding Protein 3 Is a Cofactor for
                                  Crm1-Mediated Nuclear Protein Export . . 1391
             Shasta L. Sabo and   
              Annat F. Ikin and   
          Joseph D. Buxbaum and   
                 Paul Greengard   The Alzheimer Amyloid Precursor Protein
                                  (APP) and Fe65, an APP--Binding Protein,
                                  Regulate Cell Movement . . . . . . . . . 1403
                Jon D. Lane and   
  Ma\"\ilys A. S. Vergnolle and   
          Philip G. Woodman and   
              Victoria J. Allan   Apoptotic Cleavage of Cytoplasmic Dynein
                                  Intermediate Chain and P150 $^{\rm
                                  Glued}$ Stops Dynein--Dependent Membrane
                                  Motility . . . . . . . . . . . . . . . . 1415
     Christina M. Laukaitis and   
              Donna J. Webb and   
               Karen Donais and   
                Alan F. Horwitz   Differential Dynamics of $ \alpha $5
                                  Integrin, Paxillin, and $ \alpha
                                  $-Actinin during Formation and
                                  Disassembly of Adhesions in Migrating
                                  Cells  . . . . . . . . . . . . . . . . . 1427
          Gabriela Bezakova and   
           Johannes P. Helm and   
           Maura Francolini and   
              Terje Lòmo   Effects of Purified Recombinant Neural
                                  and Muscle Agrin on Skeletal Muscle
                                  Fibers in Vivo . . . . . . . . . . . . . 1441
          Gabriela Bezakova and   
              Terje Lòmo   Muscle Activity and Muscle Agrin
                                  Regulate the Organization of
                                  Cytoskeletal Proteins and Attached
                                  Acetylcholine Receptor (Achr) Aggregates
                                  in Skeletal Muscle Fibers  . . . . . . . 1453
          David J. Dilworth and   
     Adisetyantari Suprapto and   
           Julio C. Padovan and   
             Brian T. Chait and   
         Richard W. Wozniak and   
            Michael P. Rout and   
              John D. Aitchison   Nup2p Dynamically Associates with the
                                  Distal Regions of the Yeast Nuclear Pore
                                  Complex  . . . . . . . . . . . . . . . . 1465
                  Goeh Jung and   
            Kirsten Remmert and   
                  Xufeng Wu and   
          Joanne M. Volosky and   
                 John A. Hammer   The \bionameDictyostelium Carmil Protein
                                  Links Capping Protein and the Arp2/3
                                  Complex to Type I Myosins through Their
                                  Sh3 Domains  . . . . . . . . . . . . . . 1479
              Andrew W. Tai and   
             Jen-Zen Chuang and   
                 Ching-Hwa Sung   Cytoplasmic Dynein Regulation by Subunit
                                  Heterogeneity and Its Role in Apical
                                  Transport  . . . . . . . . . . . . . . . 1499
             Manuela Vecchi and   
                Simona Polo and   
             Viviane Poupon and   
      Jan-Willem van de Loo and   
         Alexandre Benmerah and   
            Pier Paolo Di Fiore   Nucleocytoplasmic Shuttling of Endocytic
                                  Proteins . . . . . . . . . . . . . . . . 1511


Journal of Cell Biology
Volume 154, Number 1, July, 2001

                    Ira Mellman   Cell biology's journal gets a new look   9
                   Alan W. Dove   Long live the pore . . . . . . . . . . . ??
                   Alan W. Dove   Transcription in tight quarters  . . . . ??
                   Alan W. Dove   RhoA brings up the rear  . . . . . . . . ??
                   Alan W. Dove   Cataracts and NrCAM  . . . . . . . . . . ??
                   Alan W. Dove   How Toxoplasma hooks up  . . . . . . . . ??
                   Alan W. Dove   Clumping lysosomes . . . . . . . . . . . ??
               William A. Wells   Algal Rb sets size limits  . . . . . . . ??
               William A. Wells   Translation in the nucleus . . . . . . . ??
               William A. Wells   Containing the bullet  . . . . . . . . . ??
               William A. Wells   Taking tea with actin and microtubules   ??
               William A. Wells   Microtubules concentrate . . . . . . . . ??
               William A. Wells   Death and Destruction  . . . . . . . . . 14
             Susan K. Lyman and   
                   Larry Gerace   Nuclear pore complexes: dynamics in
                                  unexpected places  . . . . . . . . . . . 17
           Joseph W. Sanger and   
                 Jean M. Sanger   Fishing out proteins that bind to titin  21
             David J. Adams and   
      Louise van der Weyden and   
               Akila Mayeda and   
               Stefan Stamm and   
            Brian J. Morris and   
               John E. J. Rasko   ZNF265 --- a novel spliceosomal protein
                                  able to induce alternative splicing  . . 25
    Waltraud G. Müller and   
                Dawn Walker and   
            Gordon L. Hager and   
               James G. McNally   Large-scale chromatin decondensation and
                                  recondensation regulated by
                                  transcription from a natural promoter    33
             Enrique Samper and   
 Fermín A. Goytisolo and   
Josiane Ménissier-de Murcia and   
Eva González-Suárez and   
           Juan C. Cigudosa and   
          Gilbert de Murcia and   
         María A. Blasco   Normal telomere length and chromosomal
                                  end capping in poly(ADP-ribose)
                                  polymerase--deficient mice and primary
                                  cells despite increased chromosomal
                                  instability  . . . . . . . . . . . . . . 49
     Reynold I. Lopez-Soler and   
             Robert D. Moir and   
           Timothy P. Spann and   
               Reimer Stick and   
              Robert D. Goldman   A role for nuclear lamins in nuclear
                                  envelope assembly  . . . . . . . . . . . 61
            Nathalie Daigle and   
        Joël Beaudouin and   
              Lisa Hartnell and   
             Gabriela Imreh and   
             Einar Hallberg and   
Jennifer Lippincott-Schwartz and   
                  Jan Ellenberg   Nuclear pore complexes form immobile
                                  networks and have a very low turnover in
                                  live mammalian cells . . . . . . . . . . 71
             James N. Huang and   
                   Iha Park and   
             Eric Ellingson and   
       Laurie E. Littlepage and   
                  David Pellman   Activity of the APC$^{\rm Cdh1}$ form of
                                  the anaphase-promoting complex persists
                                  until S phase and prevents the premature
                                  expression of Cdc20p . . . . . . . . . . 85
           Anthony P. Sinai and   
                Keith A. Joiner   The Toxoplasma gondii protein ROP2
                                  mediates host organelle association with
                                  the parasitophorous vacuole membrane . . 95
               Steve Caplan and   
           Lisa M. Hartnell and   
    Rubén C. Aguilar and   
            Naava Naslavsky and   
             Juan S. Bonifacino   Human Vam6p promotes lysosome clustering
                                  and fusion in vivo . . . . . . . . . . . 109
                 Paul Young and   
            Elisabeth Ehler and   
                 Mathias Gautel   Obscurin, a giant sarcomeric Rho guanine
                                  nucleotide exchange factor protein
                                  involved in sarcomere assembly . . . . . 123
               Shigehiko Yumura   Myosin II dynamics and cortical flow
                                  during contractile ring formation in
                                  \bionameDictyostelium cells  . . . . . . 137
      Rebecca A. Worthylake and   
               Sean Lemoine and   
           Joanna M. Watson and   
                 Keith Burridge   RhoA is required for monocyte tail
                                  retraction during transendothelial
                                  migration  . . . . . . . . . . . . . . . 147
                Kip A. West and   
                Huaye Zhang and   
           Michael C. Brown and   
    Sotiris N. Nikolopoulos and   
                M. C. Riedy and   
            Alan F. Horwitz and   
          Christopher E. Turner   The LD4 motif of paxillin regulates cell
                                  spreading and motility through an
                                  interaction with paxillin kinase linker
                                  (PKL)  . . . . . . . . . . . . . . . . . 161
         Paola A. Marignani and   
       Christopher L. Carpenter   Vav2 is required for cell spreading  . . 177
     Margret I. Moré and   
            Frank-P. Kirsch and   
               Fritz G. Rathjen   Targeted ablation of NrCAM or ankyrin--B
                                  results in disorganized lens fibers
                                  leading to cataract formation  . . . . . 187
              Anh-Chi N. Le and   
                 Linda S. Musil   A novel role for FGF and extracellular
                                  signal--regulated kinase in gap
                                  junction--mediated intercellular
                                  communication in the lens  . . . . . . . 197
                      X. Xu and   
                W. E. I. Li and   
                G. Y. Huang and   
                   R. Meyer and   
                    T. Chen and   
                     Y. Luo and   
               M. P. Thomas and   
               G. L. Radice and   
                       C. W. Lo   Modulation of mouse neural crest cell
                                  motility by N-cadherin and connexin 43
                                  gap junctions  . . . . . . . . . . . . . 217
    Sophie Chappuis-Flament and   
                 Ellen Wong and   
               Les D. Hicks and   
               Cyril M. Kay and   
              Barry M. Gumbiner   Multiple cadherin extracellular repeats
                                  mediate homophilic binding and adhesion  231

Journal of Cell Biology
Volume 154, Number 2, July, 2001

                 Karin Jegalian   A dystroglycan ligand in the brain . . . ??
                 Karin Jegalian   Of coilin and Cajal bodies . . . . . . . ??
                 Karin Jegalian   Matrix patterning of digits  . . . . . . ??
                 Karin Jegalian   Tenascin turns on the EGFR . . . . . . . ??
                 Karin Jegalian   Bringing channels into the node  . . . . ??
            Tabitha M. Powledge   Fail-safe replication  . . . . . . . . . ??
            Tabitha M. Powledge   Tensegrity lives . . . . . . . . . . . . ??
            Tabitha M. Powledge   Christmas in July  . . . . . . . . . . . ??
            Tabitha M. Powledge   Keeping the lid on destruction . . . . . ??
               Jeffrey H. Miner   Mystery solved . . . . . . . . . . . . . 257
        Jonathan M. Scholey and   
          Gregory C. Rogers and   
                 David J. Sharp   Mitosis, microtubules, and the matrix    261
             Jason C. Young and   
             Ismail Moarefi and   
                F. Ulrich Hartl   Hsp90  . . . . . . . . . . . . . . . . . 267
       Emilio Arteaga-Solis and   
            Barbara Gayraud and   
                 Sui Y. Lee and   
               Lillian Shum and   
                 Lynn Sakai and   
              Francesco Ramirez   Regulation of limb patterning by
                                  extracellular microfibrils . . . . . . . 275
                    Feng Li and   
               Jianhua Chen and   
               Masako Izumi and   
             Mark C. Butler and   
            Susan M. Keezer and   
               David M. Gilbert   The replication timing program of the
                                  Chinese hamster $ \beta $-globin locus
                                  is established coincident with its
                                  repositioning near peripheral
                                  heterochromatin in early G1 phase  . . . 283
            Karen E. Tucker and   
      Maria Teresa Berciano and   
            Erica Y. Jacobs and   
            David F. LePage and   
           Karl B. Shpargel and   
        Jennifer J. Rossire and   
          Edward K. L. Chan and   
             Miguel Lafarga and   
           Ronald A. Conlon and   
              A. Gregory Matera   Residual Cajal bodies in coilin knockout
                                  mice fail to recruit Sm snRNPs and SMN,
                                  the spinal muscular atrophy gene product 293
        Andreas Hiltbrunner and   
            Jörg Bauer and   
      Pierre-Alexandre Vidi and   
           Sibylle Infanger and   
               Petra Weibel and   
               Morten Hohwy and   
                  Felix Kessler   Targeting of an abundant cytosolic form
                                  of the protein import receptor at Toc159
                                  to the outer chloroplast membrane  . . . 309
              Eija Jokitalo and   
         Noemi Cabrera-Poch and   
              Graham Warren and   
                 David T. Shima   Golgi clusters and vesicles mediate
                                  mitotic inheritance independently of the
                                  endoplasmic reticulum  . . . . . . . . . 317
           Daniel Kornitzer and   
              Rakefet Sharf and   
              Tamar Kleinberger   Adenovirus E4orf4 protein induces
                                  PP2A-dependent growth arrest in
                                  \bionameSaccharomyces cerevisiae and
                                  interacts with the anaphase-promoting
                                  complex/cyclosome  . . . . . . . . . . . 331
                  Jan Grimm and   
               Martin Sachs and   
             Stefan Britsch and   
          Silvana Di Cesare and   
      Thomas Schwarz-Romond and   
               Kari Alitalo and   
              Walter Birchmeier   Novel p62dok family members, dok-4 and
                                  dok-5, are substrates of the c--Ret
                                  receptor tyrosine kinase and mediate
                                  neuronal differentiation . . . . . . . . 345
        Kristina D. Micheva and   
             Ronald W. Holz and   
               Stephen J. Smith   Regulation of presynaptic
                                  phosphatidylinositol 4,5-biphosphate by
                                  neuronal activity  . . . . . . . . . . . 355
Héctor G. Pálmer and   
José Manuel González-Sancho and   
        Jesús Espada and   
   María T. Berciano and   
                Isabel Puig and   
              Josep Baulida and   
         Miguel Quintanilla and   
                Amparo Cano and   
Antonio García de Herreros and   
             Miguel Lafarga and   
           Alberto Muñoz   Vitamin D$_3$ promotes the
                                  differentiation of colon carcinoma cells
                                  by the induction of E-cadherin and the
                                  inhibition of $ \beta $-catenin
                                  signaling  . . . . . . . . . . . . . . . 369
        Michael Hollinshead and   
              Gaener Rodger and   
         Henriette Van Eijl and   
                 Mansun Law and   
           Ruth Hollinshead and   
           David J. T. Vaux and   
              Geoffrey L. Smith   Vaccinia virus utilizes microtubules for
                                  movement to the cell surface . . . . . . 389
                Leexan Hong and   
                Tricia Elbl and   
                 James Ward and   
   Clara Franzini-Armstrong and   
        Krystyna K. Rybicka and   
           Beth K. Gatewood and   
           David L. Baillie and   
            Elizabeth A. Bucher   MUP-4 is a novel transmembrane protein
                                  with functions in epithelial cell
                                  adhesion in \bionameCaenorhabditis
                                  elegans  . . . . . . . . . . . . . . . . 403
               Mark Bercher and   
                   Jim Wahl and   
             Bruce E. Vogel and   
                 Charles Lu and   
        Edward M. Hedgecock and   
              David H. Hall and   
             John D. Plenefisch   mua-3, a gene required for mechanical
                                  tissue integrity in
                                  \bionameCaenorhabditis elegans, encodes
                                  a novel transmembrane protein of
                                  epithelial attachment complexes  . . . . 415
     Charlotte F. Ratcliffe and   
        Ruth E. Westenbroek and   
                Rory Curtis and   
           William A. Catterall   Sodium channel $ \beta $1 and $ \beta $3
                                  subunits associate with neurofascin
                                  through their extracellular
                                  immunoglobulin-like domain . . . . . . . 427
               Shuzo Sugita and   
              Fumiaki Saito and   
                 Jiong Tang and   
                 Jakob Satz and   
             Kevin Campbell and   
          Thomas C. Südhof   A stoichiometric complex of neurexins
                                  and dystroglycan in brain  . . . . . . . 435
        Ralph Brandenberger and   
             Andrea Schmidt and   
               James Linton and   
                 Denan Wang and   
               Carey Backus and   
               Sumiko Denda and   
        Ullrich Müller and   
             Louis F. Reichardt   Identification and characterization of a
                                  novel extracellular matrix protein
                                  nephronectin that is associated with
                                  integrin $ \alpha $8$ \beta $1 in the
                                  embryonic kidney . . . . . . . . . . . . 447
           C. Scott Swindle and   
               Kien T. Tran and   
           Terry D. Johnson and   
            Pallab Banerjee and   
              Anne M. Mayes and   
             Linda Griffith and   
                     Alan Wells   Epidermal growth factor (EGF)-like
                                  repeats of human tenascin--C as ligands
                                  for EGF receptor . . . . . . . . . . . . 459

Journal of Cell Biology
Volume 154, Number 3, August, 2001

                   Alan W. Dove   Putting cell polarity on the map . . . . ??
                   Alan W. Dove   How to survive a macrophage attack . . . ??
                   Alan W. Dove   The hidden power of platelets  . . . . . ??
                   Alan W. Dove   ARNO gets things moving  . . . . . . . . ??
                   Alan W. Dove   Deleting keratins to find one  . . . . . ??
               William A. Wells   Sudden bacterial death syndrome  . . . . ??
               William A. Wells   A nurse for bicoid . . . . . . . . . . . ??
               William A. Wells   Transcription gets a licence . . . . . . ??
               William A. Wells   Formin a link to microtubules  . . . . . ??
               William A. Wells   Touching cells transform . . . . . . . . ??
               William A. Wells   Biotechnology on Parade  . . . . . . . . 482
          Stephan Lindemann and   
             Neal D. Tolley and   
               Dan A. Dixon and   
         Thomas M. McIntyre and   
        Stephen M. Prescott and   
           Guy A. Zimmerman and   
              Andrew S. Weyrich   Activated platelets mediate inflammatory
                                  signaling by regulated interleukin 1$
                                  \beta $ synthesis  . . . . . . . . . . . 485
              Masahiko Itoh and   
            Hiroyuki Sasaki and   
               Mikio Furuse and   
             Harunobu Ozaki and   
                  Toru Kita and   
              Shoichiro Tsukita   Junctional adhesion molecule (JAM) binds
                                  to PAR-3 . . . . . . . . . . . . . . . . 491
               Mark R. Frey and   
              A. Gregory Matera   RNA-mediated interaction of Cajal bodies
                                  and U2 snRNA genes . . . . . . . . . . . 499
 Fredericus J. M. van Eeden and   
         Isabel M. Palacios and   
            Mark Petronczki and   
       Matthew J. D. Weston and   
             Daniel St Johnston   Barentsz is essential for the posterior
                                  localization of oskar mRNA and
                                  colocalizes with it to the posterior
                                  pole . . . . . . . . . . . . . . . . . . 511
             Giuliana Gatti and   
               Sara Trifari and   
             Nasrin Mesaeli and   
        J. M. Robert Parker and   
             Marek Michalak and   
               Jacopo Meldolesi   Head-to-tail oligomerization of
                                  calsequestrin  . . . . . . . . . . . . . 525
            Vishwajeet Puri and   
             Rikio Watanabe and   
           Raman Deep Singh and   
           Michel Dominguez and   
          Jennifer C. Brown and   
      Christine L. Wheatley and   
             David L. Marks and   
              Richard E. Pagano   Clathrin-dependent and -independent
                                  internalization of plasma membrane
                                  sphingolipids initiates two Golgi
                                  targeting pathways . . . . . . . . . . . 535
             Becky L. Drees and   
               Bryan Sundin and   
          Elizabeth Brazeau and   
        Juliane P. Caviston and   
            Guang-Chao Chen and   
                    Wei Guo and   
         Keith G. Kozminski and   
            Michelle W. Lau and   
             John J. Moskow and   
                   Amy Tong and   
         Laura R. Schenkman and   
              Amos McKenzie and   
          Patrick Brennwald and   
              Mark Longtine and   
                   Erfei Bi and   
              Clarence Chan and   
               Peter Novick and   
              Charles Boone and   
            John R. Pringle and   
            Trisha N. Davis and   
             Stanley Fields and   
                David G. Drubin   A protein interaction map for cell
                                  polarity development . . . . . . . . . . 549
       Shyuichiro Matsubara and   
                 Masayuki Ozawa   Expression of $ \alpha $-catenin in $
                                  \alpha $-catenin--deficient cells
                                  increases resistance to
                                  sphingosine-induced apoptosis  . . . . . 573
               Joaquim Egea and   
              Carme Espinet and   
              Rosa M. Soler and   
              Xavier Dolcet and   
     Víctor J. Yuste and   
              Mario Encinas and   
        Montserrat Iglesias and   
         Nativitat Rocamora and   
                Joan X. Comella   Neuronal survival induced by
                                  neurotrophins requires calmodulin  . . . 585
          Lorraine C. Santy and   
              James E. Casanova   Activation of ARF6 by ARNO stimulates
                                  epithelial cell migration through
                                  downstream activation of both Rac1 and
                                  phospholipase D  . . . . . . . . . . . . 599
             Victoria Hatch and   
                   Gang Zhi and   
                 Lula Smith and   
             James T. Stull and   
                Roger Craig and   
                 William Lehman   Myosin light chain kinase binding to a
                                  unique site on F-actin revealed by
                                  three-dimensional image reconstruction   611
            Sonja M. Wojcik and   
            Mary A. Longley and   
                 Dennis R. Roop   Discovery of a novel murine keratin 6
                                  (K6) isoform explains the absence of
                                  hair and nail defects in mice deficient
                                  for K6a and K6b  . . . . . . . . . . . . 619
          Rutilio A. Fratti and   
         Jonathan M. Backer and   
             Jean Gruenberg and   
             Silvia Corvera and   
                   Vojo Deretic   Role of phosphatidylinositol $3$-kinase
                                  and Rab5 effectors in phagosomal
                                  biogenesis and mycobacterial phagosome
                                  maturation arrest  . . . . . . . . . . . 631
          Bridget S. Wilson and   
          Janet R. Pfeiffer and   
           Zurab Surviladze and   
        Elizabeth A. Gaudet and   
                Janet M. Oliver   High resolution mapping of mast cell
                                  membranes reveals primary and secondary
                                  domains of Fc$ \epsilon $RI and LAT  . . 645
                Bill Newman and   
            Laure I. Gigout and   
                Laure Sudre and   
           Michael E. Grant and   
              Gillian A. Wallis   Coordinated expression of matrix Gla
                                  protein is required during endochondral
                                  ossification for chondrocyte survival    659

Journal of Cell Biology
Volume 154, Number 4, August, 2001

               William A. Wells   Cross-linking can be good  . . . . . . . ??
               William A. Wells   CENP-E falls off . . . . . . . . . . . . ??
               William A. Wells   Compartmentalized insulin signaling  . . ??
               William A. Wells   Zones and rings in wound healing . . . . ??
               William A. Wells   Making virus in the axon . . . . . . . . ??
            Tabitha M. Powledge   Garbage in, garbage out  . . . . . . . . ??
            Tabitha M. Powledge   Running interference . . . . . . . . . . ??
            Tabitha M. Powledge   Cell cycling with Rac  . . . . . . . . . ??
            Tabitha M. Powledge   The (formerly) missing link  . . . . . . ??
            Tabitha M. Powledge   Shedding light on protein folding  . . . ??
         Isabel M. Olazabal and   
              Laura M. Machesky   Abp1p and cortactin, new ``hand-holds''
                                  for actin  . . . . . . . . . . . . . . . 679
              Beth Sullivan and   
                    Gary Karpen   Centromere identity in
                                  \bionameDrosophila is not determined in
                                  vivo by replication timing . . . . . . . 683
            Conrad L. Leung and   
                  Min Zheng and   
            Susan M. Prater and   
              Ronald K. H. Liem   The BPAG1 locus  . . . . . . . . . . . . 691
                     Jun Xu and   
                    Dan Liu and   
                Gordon Gill and   
                  Zhou Songyang   Regulation of cytokine-independent
                                  survival kinase (CISK) by the Phox
                                  homology domain and phosphoinositides    699
            Leana M. Topper and   
            Holger Bastians and   
           Joan V. Ruderman and   
                Gary J. Gorbsky   Elevating the level of Cdc34/Ubc3
                                  ubiquitin-conjugating enzyme in mitosis
                                  inhibits association of CENP-E with
                                  kinetochores and blocks the metaphase
                                  alignment of chromosomes . . . . . . . . 707
              Kenneth Cline and   
                    Hiroki Mori   Thylakoid $ \Delta $ pH-dependent
                                  precursor proteins bind to a
                                  cpTatC--Hcf106 complex before
                                  Tha4-dependent transport . . . . . . . . 719
            Philippe Cupers and   
          Mustapha Bentahir and   
        Katleen Craessaerts and   
            Isabelle Orlans and   
        Hugo Vanderstichele and   
                Paul Saftig and   
           Bart De Strooper and   
                    Wim Annaert   The discrepancy between presenilin
                                  subcellular localization and $ \gamma
                                  $-secretase processing of amyloid
                                  precursor protein  . . . . . . . . . . . 731
            M. J. Tomishima and   
                  L. W. Enquist   A conserved $ \alpha $-herpesvirus
                                  protein necessary for axonal
                                  localization of viral membrane proteins  741
              Wilhelm Bloch and   
                    Yun Fan and   
                     Ji Han and   
                  Sheng Xue and   
    Torsten Schöneberg and   
                  Guanju Ji and   
                Zhong J. Lu and   
            Michael Walther and   
      Reinhard Fässler and   
      Jürgen Hescheler and   
              Klaus Addicks and   
           Bernd K. Fleischmann   Disruption of cytoskeletal integrity
                                  impairs G$_i$-mediated signaling due to
                                  displacement of G$_i$ proteins . . . . . 753
    Stéphane Gilbert and   
              Anne Loranger and   
            Nathalie Daigle and   
                Normand Marceau   Simple epithelium keratins 8 and 18
                                  provide resistance to Fas-mediated
                                  apoptosis. The protection occurs through
                                  a receptor-targeting modulation  . . . . 763
               Walter Witke and   
                     Wei Li and   
       David J. Kwiatkowski and   
         Frederick S. Southwick   Comparisons of CapG and gelsolin-null
                                  macrophages  . . . . . . . . . . . . . . 775
           Craig A. Mandato and   
              William M. Bement   Contraction and polymerization cooperate
                                  to assemble and close actomyosin rings
                                  around \bionameXenopus oocyte wounds . . 785
           Liliane Michalik and   
  Béatrice Desvergne and   
             Nguan Soon Tan and   
        Sharmila Basu-Modak and   
              Pascal Escher and   
          Jennifer Rieusset and   
          Jeffrey M. Peters and   
           Gürkan Kaya and   
          Frank J. Gonzalez and   
              Jozsef Zakany and   
             Daniel Metzger and   
             Pierre Chambon and   
              Denis Duboule and   
                   Walter Wahli   Impaired skin wound healing in
                                  peroxisome proliferator--activated
                                  receptor (PPAR) $ \alpha $ and PPAR $
                                  \beta $ mutant mice  . . . . . . . . . . 799
                    Rui Lin and   
      Bonnie J. Warn-Cramer and   
            Wendy E. Kurata and   
                    Alan F. Lau   v-Src phosphorylation of connexin 43 on
                                  Tyr247 and Tyr265 disrupts gap
                                  junctional communication . . . . . . . . 815
           Robert T. Watson and   
         Satoshi Shigematsu and   
          Shian-Huey Chiang and   
                Silvia Mora and   
             Makoto Kanzaki and   
              Ian G. Macara and   
            Alan R. Saltiel and   
              Jeffrey E. Pessin   Lipid raft microdomain
                                  compartmentalization of TC10 is required
                                  for insulin signaling and GLUT4
                                  translocation  . . . . . . . . . . . . . 829
                Lihsia Chen and   
                  Bryan Ong and   
                   Vann Bennett   LAD-1, the \bionameCaenorhabditis
                                  elegans L1CAM homologue, participates in
                                  embryonic and gonadal morphogenesis and
                                  is a substrate for fibroblast growth
                                  factor receptor pathway-dependent
                                  phosphotyrosine-based signaling  . . . . 841
            Nadine Jarousse and   
                 Regis B. Kelly   The AP2 binding site of synaptotagmin 1
                                  is not an internalization signal but a
                                  regulator of endocytosis . . . . . . . . 857
            Laurie Stepanek and   
                 Qi Lun Sun and   
                   Jun Wang and   
                  Cong Wang and   
                  John L. Bixby   CRYP-2\slash cPTPRO is a neurite
                                  inhibitory repulsive guidance cue for
                                  retinal neurons in vitro . . . . . . . . 867
           William A. Edens and   
              Lisa Sharling and   
             Guangjie Cheng and   
            Raymond Shapira and   
          Joseph M. Kinkade and   
                Taehoon Lee and   
           Heather A. Edens and   
                Xuexin Tang and   
           Cameron Sullards and   
         Denise B. Flaherty and   
              Guy M. Benian and   
               J. David Lambeth   Tyrosine cross-linking of extracellular
                                  matrix is catalyzed by Duox, a
                                  multidomain oxidase/peroxidase with
                                  homology to the phagocyte oxidase
                                  subunit gp91 phox  . . . . . . . . . . . 879

Journal of Cell Biology
Volume 154, Number 5, September, 2001

                   Alan W. Dove   Collagen reveals a hidden talent . . . . ??
                   Alan W. Dove   The spindle assembly checkpoint gets a
                                  complex  . . . . . . . . . . . . . . . . ??
                   Alan W. Dove   Flight of the titins . . . . . . . . . . ??
                   Alan W. Dove   Chk1, Chk2, is the amplifier on? . . . . ??
                   Alan W. Dove   Two new ways to eat beans  . . . . . . . ??
               William A. Wells   All skin and brain . . . . . . . . . . . ??
               William A. Wells   An organelle knockout  . . . . . . . . . ??
               William A. Wells   Squeezing in with sugar  . . . . . . . . ??
               William A. Wells   Rafts to the front; rafts to the rear    ??
               William A. Wells   Cohesin's cohesion . . . . . . . . . . . ??
               William A. Wells   Histones Rule!: The FASEB Conference on
                                  Chromatin and Transcription. July 7--12,
                                  2001 . . . . . . . . . . . . . . . . . . 906
                 M. Andrew Hoyt   A new view of the spindle checkpoint . . 909
              Carmen Feijoo and   
         Clare Hall-Jackson and   
                    Rong Wu and   
              David Jenkins and   
                Jane Leitch and   
           David M. Gilbert and   
                    Carl Smythe   Activation of mammalian Chk1 during DNA
                                  replication arrest . . . . . . . . . . . 913
             Valery Sudakin and   
          Gordon K. T. Chan and   
                     Tim J. Yen   Checkpoint inhibition of the APC/C in
                                  HeLa cells is mediated by a complex of
                                  BUBR1, BUB3, CDC20, and MAD2 . . . . . . 925
             Daniel Denning and   
              Brook Mykytka and   
          Nadia P. C. Allen and   
                  Lan Huang and   
              Al Burlingame and   
                 Michael Rexach   The nucleoporin Nup60p functions as a
                                  Gsp1p--GTP--sensitive tether for Nup2p
                                  at the nuclear pore complex  . . . . . . 937
  Renée S. Polizotto and   
                Martha S. Cyert   Calcineurin-dependent nuclear import of
                                  the transcription factor Crz1p requires
                                  Nmd5p  . . . . . . . . . . . . . . . . . 951
         Kimitoshi Nakamura and   
               Anna Zuppini and   
            Serge Arnaudeau and   
              Jeffery Lynch and   
                Irfan Ahsan and   
               Ryoko Krause and   
                Sylvia Papp and   
           Humbert De Smedt and   
               Jan B. Parys and   
  Werner Müller-Esterl and   
              Daniel P. Lew and   
          Karl-Heinz Krause and   
           Nicolas Demaurex and   
                Michal Opas and   
                 Marek Michalak   Functional specialization of
                                  calreticulin domains . . . . . . . . . . 961
           Kiminori Toyooka and   
            Takashi Okamoto and   
               Takao Minamikawa   Cotyledon cells of \bionameVigna mungo
                                  seedlings use at least two distinct
                                  autophagic machineries for degradation
                                  of starch granules and cellular
                                  components . . . . . . . . . . . . . . . 973
                  Ethan Lee and   
               Adrian Salic and   
              Marc W. Kirschner   Physiological regulation of $ \beta
                                  $-catenin stability by Tcf3 and CK1$
                                  \epsilon $ . . . . . . . . . . . . . . . 983
                 Nina Orike and   
            Gayle Middleton and   
             Emma Borthwick and   
           Vladimir Buchman and   
              Timothy Cowen and   
                 Alun M. Davies   Role of PI $3$-kinase, Akt and
                                  Bcl-2--related proteins in sustaining
                                  the survival of neurotrophic
                                  factor--independent adult sympathetic
                                  neurons  . . . . . . . . . . . . . . . . 995
            Fraser D. Brown and   
          Andrew L. Rozelle and   
               Helen L. Yin and   
         Tamás Balla and   
             Julie G. Donaldson   Phosphatidylinositol 4,5-bisphosphate
                                  and Arf6-regulated membrane traffic  . . 1007
             Joshua Sussman and   
               David Stokoe and   
             Natalya Ossina and   
                Emma Shtivelman   Protein kinase B phosphorylates AHNAK
                                  and regulates its subcellular
                                  localization . . . . . . . . . . . . . . 1019
              Giorgio Scita and   
            Pierluigi Tenca and   
          Liliana B. Areces and   
          Arianna Tocchetti and   
          Emanuela Frittoli and   
        Giuseppina Giardina and   
        Isabella Ponzanelli and   
              Patrizia Sini and   
          Metello Innocenti and   
            Pier Paolo Di Fiore   An effector region in Eps8 is
                                  responsible for the activation of the
                                  Rac-specific GEF activity of Sos-1 and
                                  for the proper localization of the
                                  Rac-based actin--polymerizing machine    1031
              Michael Kulke and   
             Ciprian Neagoe and   
          Bernhard Kolmerer and   
               Ave Minajeva and   
              Horst Hinssen and   
            Belinda Bullard and   
              Wolfgang A. Linke   Kettin, a major source of myofibrillar
                                  stiffness in \bionameDrosophila indirect
                                  flight muscle  . . . . . . . . . . . . . 1045
                 Koichi Ito and   
            Shinji Komazaki and   
         Kazushige Sasamoto and   
          Morikatsu Yoshida and   
               Miyuki Nishi and   
             Kenji Kitamura and   
              Hiroshi Takeshima   Deficiency of triad junction and
                                  contraction in mutant skeletal muscle
                                  lacking junctophilin type 1  . . . . . . 1059
                Jingsong Xu and   
          Dorothy Rodriguez and   
            Eric Petitclerc and   
               Jenny J. Kim and   
            Masanori Hangai and   
               S. Moon Yuen and   
            George E. Davis and   
                Peter C. Brooks   Proteolytic exposure of a cryptic site
                                  within collagen type IV is required for
                                  angiogenesis and tumor growth in vivo    1069
             Jan L. Sechler and   
                Hongwei Rao and   
        Anne Marie Cumiskey and   
   Irbert Vega-Colón and   
           Michael S. Smith and   
           Takatoshi Murata and   
           Jean E. Schwarzbauer   A novel fibronectin binding site
                                  required for fibronectin fibril growth
                                  during matrix assembly . . . . . . . . . 1081

Journal of Cell Biology
Volume 154, Number 6, September, 2001

               William A. Wells   Joined at the Hip  . . . . . . . . . . . ??
               William A. Wells   Sticky utrophin messages . . . . . . . . ??
               William A. Wells   Cooperation in the cerebellum  . . . . . ??
               William A. Wells   Mitosis without wind . . . . . . . . . . ??
               William A. Wells   From nuclear pore to kinetochore . . . . ??
                   Vicki Glaser   Tales from the crypt . . . . . . . . . . ??
                   Vicki Glaser   Antagonistic drivers share BuMPy pathway ??
                   Vicki Glaser   Arp bent out of shape  . . . . . . . . . ??
                   Vicki Glaser   Desmosomes sort it out . . . . . . . . . ??
                   Vicki Glaser   Tagged From birth  . . . . . . . . . . . ??
               William A. Wells   Searching for a spindle matrix . . . . . 1102
        Yuko Mimori-Kiyosue and   
              Shoichiro Tsukita   Where is APC going?  . . . . . . . . . . 1105
            Joan B. Mannick and   
      Christopher Schonhoff and   
             Natalia Papeta and   
         Pedram Ghafourifar and   
              Marten Szibor and   
               Kezhong Fang and   
                Benjamin Gaston   S-Nitrosylation of mitochondrial
                                  caspases . . . . . . . . . . . . . . . . 1111
          Cynthia A. Earles and   
                 Jihong Bai and   
                  Ping Wang and   
               Edwin R. Chapman   The tandem C2 domains of synaptotagmin
                                  contain redundant Ca$^2$ + binding sites
                                  that cooperate to engage t--SNAREs and
                                  trigger exocytosis . . . . . . . . . . . 1117
            Tarun M. Kapoor and   
           Timothy J. Mitchison   Eg5 is static in bipolar spindles
                                  relative to tubulin  . . . . . . . . . . 1125
           Aime A. Levesque and   
               Duane A. Compton   The chromokinesin Kid is necessary for
                                  chromosome arm orientation and
                                  oscillation, but not congression, on
                                  mitotic spindles . . . . . . . . . . . . 1135
          Na\"\ima Belgareh and   
  Gwénaël Rabut and   
            Siau Wei Ba\"\i and   
         Megan van Overbeek and   
        Joël Beaudouin and   
            Nathalie Daigle and   
          Olga V. Zatsepina and   
             Fabien Pasteau and   
       Valérie Labas and   
   Micheline Fromont-Racine and   
              Jan Ellenberg and   
            Valérie Doye   An evolutionarily conserved NPC
                                  subcomplex, which redistributes in part
                                  to kinetochores in mammalian cells . . . 1147
              Xiangming Gao and   
              Tanya Chandra and   
     Michel-Olivier Gratton and   
      Isabelle Quélo and   
    Josée Prud'homme and   
            Stefano Stifani and   
          René St-Arnaud   HES6 acts as a transcriptional repressor
                                  in myoblasts and can induce the myogenic
                                  differentiation program  . . . . . . . . 1161
       Anthony O. Gramolini and   
        Guy Bélanger and   
              Bernard J. Jasmin   Distinct regions in the 3' untranslated
                                  region are responsible for targeting and
                                  stabilizing utrophin transcripts in
                                  skeletal muscle cells  . . . . . . . . . 1173
         Andreas Stockinger and   
               Andreas Eger and   
                 Julia Wolf and   
               Hartmut Beug and   
                 Roland Foisner   E-cadherin regulates cell growth by
                                  modulating proliferation-dependent $
                                  \beta $-catenin transcriptional activity 1185
             Pamela L. Tuma and   
            Lydia K. Nyasae and   
         Jonathan M. Backer and   
                 Ann L. Hubbard   Vps34p differentially regulates
                                  endocytosis from the apical and
                                  basolateral domains in polarized hepatic
                                  cells  . . . . . . . . . . . . . . . . . 1197
Åsa E. Y. Engqvist-Goldstein and   
            Robin A. Warren and   
         Michael M. Kessels and   
              James H. Keen and   
                John Heuser and   
                David G. Drubin   The actin-binding protein Hip1R
                                  associates with clathrin during early
                                  stages of endocytosis and promotes
                                  clathrin assembly in vitro . . . . . . . 1209
                 Songwei Wu and   
             Jose Sangerman and   
                    Ming Li and   
           George H. Brough and   
          Steven R. Goodman and   
                   Troy Stevens   Essential control of an endothelial cell
                                  I$_{SOC}$ by the spectrin membrane
                                  skeleton . . . . . . . . . . . . . . . . 1225
           Monica Carmosino and   
           Giuseppe Procino and   
       Grazia Paola Nicchia and   
           Roberta Mannucci and   
        Jean-Marc Verbavatz and   
              Ren\`ee Gobin and   
               Maria Svelto and   
               Giovanna Valenti   Histamine treatment induces
                                  rearrangements of orthogonal arrays of
                                  particles (OAPs) in human
                                  AQP4-expressing gastric cells  . . . . . 1235
              Song-Kyu Park and   
              Robert Miller and   
                  Ian Krane and   
              Timothy Vartanian   The erbB2 gene is required for the
                                  development of terminally differentiated
                                  spinal cord oligodendrocytes . . . . . . 1245
            Takeshi Sakurai and   
                Marc Lustig and   
             Joanne Babiarz and   
        Andrew J. W. Furley and   
                Steven Tait and   
            Peter J. Brophy and   
           Stephen A. Brown and   
             Lucia Y. Brown and   
             Carol A. Mason and   
                  Martin Grumet   Overlapping functions of the cell
                                  adhesion molecules Nr--CAM and L1 in
                                  cerebellar granule cell development  . . 1259


Journal of Cell Biology
Volume 155, Number 1, October, 2001

                   Alan W. Dove   Saying NO to muscular dystrophy  . . . . ??
                   Alan W. Dove   Muscle cells experience a nuclear
                                  buildup  . . . . . . . . . . . . . . . . ??
               William A. Wells   Bone breakage  . . . . . . . . . . . . . ??
                   Alan W. Dove   Apical transport gets motorized  . . . . ??
                   Alan W. Dove   Knock twice before invading  . . . . . . ??
                   Alan W. Dove   Disgorging the MVB . . . . . . . . . . . ??
               William A. Wells   Wingless and the argosomes . . . . . . . ??
               William A. Wells   Cold-induced dwarfism  . . . . . . . . . ??
               William A. Wells   Actin's origins  . . . . . . . . . . . . ??
               William A. Wells   Beware the Borg  . . . . . . . . . . . . ??
               William A. Wells   Remaking the heart . . . . . . . . . . . ??
          David J. Gillooly and   
              Anne Simonsen and   
                Harald Stenmark   Phosphoinositides and phagocytosis . . . 15
           Otilia V. Vieira and   
         Roberto J. Botelho and   
                Lucia Rameh and   
        Saskia M. Brachmann and   
            Tsuyoshi Matsuo and   
         Howard W. Davidson and   
             Alan Schreiber and   
         Jonathan M. Backer and   
           Lewis C. Cantley and   
               Sergio Grinstein   Distinct roles of class I and class III
                                  phosphatidylinositol $3$-kinases in
                                  phagosome formation and maturation . . . 19
                  Yewei Liu and   
Zoltán Cseresnyés and   
         William R. Randall and   
            Martin F. Schneider   Activity-dependent nuclear translocation
                                  and intranuclear distribution of NFATc
                                  in adult skeletal muscle fibers  . . . . 27
        Kathryn J. Mitchell and   
               Paolo Pinton and   
               Aniko Varadi and   
            Carlo Tacchetti and   
          Edward K. Ainscow and   
              Tullio Pozzan and   
            Rosario Rizzuto and   
                  Guy A. Rutter   Dense core secretory vesicles revealed
                                  as a dynamic Ca$^{2+}$ store in
                                  neuroendocrine cells with a
                                  vesicle-associated membrane protein
                                  \bionameaequorin chimaera  . . . . . . . 41
          Monique Kleijmeer and   
                 Georg Ramm and   
          Danita Schuurhuis and   
            Janice Griffith and   
             Maria Rescigno and   
 Paola Ricciardi-Castagnoli and   
      Alexander Y. Rudensky and   
            Ferry Ossendorp and   
      Cornelis J. M. Melief and   
          Willem Stoorvogel and   
                  Hans J. Geuze   Reorganization of multivesicular bodies
                                  regulates MHC class II antigen
                                  presentation by dendritic cells  . . . . 53
                Junlin Teng and   
               Yosuke Takei and   
             Akihiro Harada and   
               Takao Nakata and   
               Jianguo Chen and   
              Nobutaka Hirokawa   Synergistic effects of MAP2 and MAP1B
                                  knockout in neuronal migration,
                                  dendritic outgrowth, and microtubule
                                  organization . . . . . . . . . . . . . . 65
                Yasuko Noda and   
              Yasushi Okada and   
             Nobuhito Saito and   
           Mitsutoshi Setou and   
                    Ying Xu and   
             Zheizeng Zhang and   
              Nobutaka Hirokawa   KIFC3, a microtubule minus end--directed
                                  motor for the apical transport of
                                  annexin XIIIb--associated
                                  Triton-insoluble membranes . . . . . . . 77
              Justin Skoble and   
          Victoria Auerbuch and   
              Erin D. Goley and   
           Matthew D. Welch and   
              Daniel A. Portnoy   Pivotal role of VASP in Arp2/3
                                  complex--mediated actin nucleation,
                                  actin branch-formation, and
                                  \bionameListeria monocytogenes motility  89
     Hél\`ene Bierne and   
                Edith Gouin and   
                Pascal Roux and   
                Pico Caroni and   
               Helen L. Yin and   
                Pascale Cossart   A role for cofilin and LIM kinase in
                                  \bionameListeria-induced phagocytosis    101
            Marvin E. Adams and   
         Heather A. Mueller and   
            Stanley C. Froehner   In vivo requirement of the $ \alpha
                                  $-syntrophin PDZ domain for the
                                  sarcolemmal localization of nNOS and
                                  aquaporin-4  . . . . . . . . . . . . . . 113
           Michelle Wehling and   
         Melissa J. Spencer and   
               James G. Tidball   A nitric oxide synthase transgene
                                  ameliorates muscular dystrophy in mdx
                                  mice . . . . . . . . . . . . . . . . . . 123
          Isabelle Hoffmann and   
          Emmanuel Eug\`ene and   
              Xavier Nassif and   
     Pierre-Olivier Couraud and   
           Sandrine Bourdoulous   Activation of ErbB2 receptor tyrosine
                                  kinase supports invasion of endothelial
                                  cells by Neisseria meningitidis  . . . . 133
                  Oren Dwir and   
         Geoffrey S. Kansas and   
                     Ronen Alon   Cytoplasmic anchorage of L-selectin
                                  controls leukocyte capture and rolling
                                  by increasing the mechanical stability
                                  of the selectin tether . . . . . . . . . 145
               Wenguang Liu and   
            Satoru Toyosawa and   
           Tatsuya Furuichi and   
             Naoko Kanatani and   
           Carolina Yoshida and   
                   Yang Liu and   
                Miki Himeno and   
               Satoru Narai and   
            Akira Yamaguchi and   
               Toshihisa Komori   Overexpression of Cbfa1 in osteoblasts
                                  inhibits osteoblast maturation and
                                  causes osteopenia with multiple
                                  fractures  . . . . . . . . . . . . . . . 157

Journal of Cell Biology
Volume 155, Number 2, October, 2001

               William A. Wells   An extended release for surfactant . . . ??
               William A. Wells   Virus one; laminin nil . . . . . . . . . ??
               William A. Wells   Bind and bend  . . . . . . . . . . . . . ??
               William A. Wells   p115 untethered  . . . . . . . . . . . . ??
               William A. Wells   Exchanging clathrin  . . . . . . . . . . ??
                   Mitch Leslie   Stayin' alive, without antigen . . . . . ??
                   Mitch Leslie   A mobile transcription factor  . . . . . ??
                   Mitch Leslie   Sizing up cell division  . . . . . . . . ??
                   Mitch Leslie   Leaf starter . . . . . . . . . . . . . . ??
                   Mitch Leslie   Death by mistake . . . . . . . . . . . . ??
                    Tom Misteli   The concept of self-organization in
                                  cellular architecture  . . . . . . . . . 181
            Andrew E. Aplin and   
                  R. L. Juliano   Regulation of nucleocytoplasmic
                                  trafficking by cell adhesion receptors
                                  and the cytoskeleton . . . . . . . . . . 187
           Khashayar Farsad and   
             Niels Ringstad and   
                Kohji Takei and   
             Scott R. Floyd and   
               Kristin Rose and   
              Pietro De Camilli   Generation of high curvature membranes
                                  mediated by direct endophilin bilayer
                                  interactions . . . . . . . . . . . . . . 193
                  Kai Schuh and   
           Stjepan Uldrijan and   
             Myriam Telkamp and   
       Nicola Röthlein and   
                  Ludwig Neyses   The plasmamembrane calmodulin-dependent
                                  calcium pump . . . . . . . . . . . . . . 201
               Andre Fortin and   
             Sean P. Cregan and   
         Jason G. MacLaurin and   
             Neena Kushwaha and   
            Emma S. Hickman and   
        Charlie S. Thompson and   
              Antoine Hakim and   
             Paul R. Albert and   
          Francesco Cecconi and   
             Kristian Helin and   
              David S. Park and   
                  Ruth S. Slack   APAF1 is a key transcriptional target
                                  for p53 in the regulation of neuronal
                                  cell death . . . . . . . . . . . . . . . 207
           Janice Robertson and   
       Jean-Martin Beaulieu and   
      Mohammad M. Doroudchi and   
          Heather D. Durham and   
         Jean-Pierre Julien and   
            Walter E. Mushynski   Apoptotic death of neurons exhibiting
                                  peripherin aggregates is mediated by the
                                  proinflammatory cytokine tumor necrosis
                                  factor-$ \alpha $  . . . . . . . . . . . 217
  Manojkumar A. Puthenveedu and   
               Adam D. Linstedt   Evidence that Golgi structure depends on
                                  a p115 activity that is independent of
                                  the vesicle tether components giantin
                                  and GM130  . . . . . . . . . . . . . . . 227
                Maren Heese and   
              Xavier Gansel and   
            Liliane Sticher and   
                 Peter Wick and   
               Markus Grebe and   
           Fabienne Granier and   
              Gerd Jürgens   Functional characterization of the
                                  KNOLLE-interacting t--SNARE AtSNAP33 and
                                  its role in plant cytokinesis  . . . . . 239
            Sandra Palmgren and   
             Pauli J. Ojala and   
             Martin A. Wear and   
             John A. Cooper and   
              Pekka Lappalainen   Interactions with PIP$_2$, ADP-actin
                                  monomers, and capping protein regulate
                                  the activity and localization of yeast
                                  twinfilin  . . . . . . . . . . . . . . . 251
              Terry Lechler and   
       Gudrun A. Jonsdottir and   
             Saskia K. Klee and   
              David Pellman and   
                        Rong Li   A two-tiered mechanism by which Cdc42
                                  controls the localization and activation
                                  of an Arp2/3-activating motor complex in
                                  yeast  . . . . . . . . . . . . . . . . . 261
      Florian Mullershausen and   
           Michael Russwurm and   
         W. Joseph Thompson and   
                     Li Liu and   
             Doris Koesling and   
                 Andreas Friebe   Rapid nitric oxide--induced
                                  desensitization of the cGMP response is
                                  caused by increased activity of
                                  phosphodiesterase type 5 paralleled by
                                  phosphorylation of the enzyme  . . . . . 271
              Thomas Haller and   
                 Paul Dietl and   
           Kristian Pfaller and   
              Manfred Frick and   
               Norbert Mair and   
           Markus Paulmichl and   
            Michael W. Hess and   
        Johannes Fürst and   
                      Karl Maly   Fusion pore expansion is a slow,
                                  discontinuous, and Ca$^{2+}$-dependent
                                  process regulating secretion from
                                  alveolar type II cells . . . . . . . . . 279
                  Xufeng Wu and   
              Xiaohong Zhao and   
              Lauren Baylor and   
            Shivani Kaushal and   
             Evan Eisenberg and   
                 Lois E. Greene   Clathrin exchange during
                                  clathrin-mediated endocytosis  . . . . . 291
                Stefan Kunz and   
       Noemí Sevilla and   
         Dorian B. McGavern and   
          Kevin P. Campbell and   
         Michael B. A. Oldstone   Molecular analysis of the interaction of
                                  LCMV with its cellular receptor $ \alpha
                                  $-dystroglycan . . . . . . . . . . . . . 301

Journal of Cell Biology
Volume 155, Number 3, October, 2001

                   Alan W. Dove   Potential muscles everywhere . . . . . . ??
                   Alan W. Dove   Shape up or ship out . . . . . . . . . . ??
                   Alan W. Dove   How big is your organelle? . . . . . . . ??
                   Alan W. Dove   Death by unligated integrin  . . . . . . ??
                   Alan W. Dove   The growth cone gets a grip  . . . . . . ??
               William A. Wells   Old cells gone bad . . . . . . . . . . . ??
               William A. Wells   Sustained specificity  . . . . . . . . . ??
               William A. Wells   Swimming with sperm  . . . . . . . . . . ??
               William A. Wells   Arms together, CENs apart  . . . . . . . ??
               William A. Wells   Killing for love . . . . . . . . . . . . ??
                  Daniel G. Jay   A Src-astic response to mounting tension 327
            Martin Villalba and   
                     Kun Bi and   
         Fernando Rodriguez and   
           Yoshihiko Tanaka and   
       Stephen Schoenberger and   
                   Amnon Altman   Vav1\slash Rac-dependent actin
                                  cytoskeleton reorganization is required
                                  for lipid raft clustering in T cells . . 331
                Sanjay Vasu and   
               Sundeep Shah and   
              Arturo Orjalo and   
                Minkyu Park and   
        Wolfgang H. Fischer and   
             Douglass J. Forbes   Novel vertebrate nucleoporins Nup133 and
                                  Nup160 play a role in mRNA export  . . . 339
             Shilpa Vashist and   
                  Woong Kim and   
          William J. Belden and   
              Eric D. Spear and   
            Charles Barlowe and   
                 Davis T. W. Ng   Distinct retrieval and retention
                                  mechanisms are required for the quality
                                  control of endoplasmic reticulum protein
                                  folding  . . . . . . . . . . . . . . . . 355
                Hein Sprong and   
            Sophie Degroote and   
             Tijs Claessens and   
          Judith van Drunen and   
             Viola Oorschot and   
        Ben H. C. Westerink and   
         Yoshio Hirabayashi and   
          Judith Klumperman and   
       Peter van der Sluijs and   
                Gerrit van Meer   Glycosphingolipids are required for
                                  sorting melanosomal proteins in the
                                  Golgi complex  . . . . . . . . . . . . . 369
          Jacquelyn Gerhart and   
                 Brian Bast and   
            Christine Neely and   
              Stephanie Iem and   
               Paula Amegbe and   
          Robert Niewenhuis and   
             Steven Miklasz and   
             Pei Feng Cheng and   
         Mindy George-Weinstein   MyoD-positive myoblasts are present in
                                  mature fetal organs lacking skeletal
                                  muscle . . . . . . . . . . . . . . . . . 381
               Astrid Weins and   
              Karin Schwarz and   
             Christian Faul and   
             Laura Barisoni and   
          Wolfgang A. Linke and   
                   Peter Mundel   Differentiation- and stress-dependent
                                  nuclear cytoplasmic redistribution of
                                  myopodin, a novel actin-bundling protein 393
        Wallace F. Marshall and   
              Joel L. Rosenbaum   Intraflagellar transport balances
                                  continuous turnover of outer doublet
                                  microtubules . . . . . . . . . . . . . . 405
             Hiroyasu Inada and   
               Ichiro Izawa and   
           Miwako Nishizawa and   
               Eriko Fujita and   
               Tohru Kiyono and   
        Toshitada Takahashi and   
              Takashi Momoi and   
                 Masaki Inagaki   Keratin attenuates tumor necrosis
                                  factor--induced cytotoxicity through
                                  association with TRADD . . . . . . . . . 415
            Daniel M. Suter and   
                  Paul Forscher   Transmission of growth cone traction
                                  force through apCAM--cytoskeletal
                                  linkages is regulated by Src family
                                  tyrosine kinase activity . . . . . . . . 427
                   Wenbo Xu and   
                Michael Shy and   
               John Kamholz and   
              Lisa Elferink and   
                    Gang Xu and   
                Jack Lilien and   
                  Janne Balsamo   Mutations in the cytoplasmic domain of
                                  P0 reveal a role for PKC-mediated
                                  phosphorylation in adhesion and
                                  myelination  . . . . . . . . . . . . . . 439
            Agnese Mariotti and   
          Paul A. Kedeshian and   
               Michael Dans and   
        Anna Maria Curatola and   
   Laurent Gagnoux-Palacios and   
           Filippo G. Giancotti   EGF-R signaling through Fyn kinase
                                  disrupts the function of integrin $
                                  \alpha $6$ \beta $4 at hemidesmosomes    447
          Dwayne G. Stupack and   
             Xose S. Puente and   
  Souphaphone Boutsaboualoy and   
          Chris M. Storgard and   
               David A. Cheresh   Apoptosis of adherent cells by
                                  recruitment of caspase-8 to unligated
                                  integrins  . . . . . . . . . . . . . . . 459
       Victoria L. Seewaldt and   
    Krzysztof Mrózek and   
                Randy Sigle and   
             Eric C. Dietze and   
                Kevin Heine and   
        David M. Hockenbery and   
         Katherine B. Hobbs and   
          L. Elizabeth Caldwell   Suppression of p53 function in normal
                                  human mammary epithelial cells increases
                                  sensitivity to extracellular
                                  matrix--induced apoptosis  . . . . . . . 471

Journal of Cell Biology
Volume 155, Number 4, November, 2001

               William A. Wells   Cleaving and migrating . . . . . . . . . ??
               William A. Wells   Battle of the actin junctions  . . . . . ??
               William A. Wells   Toxic apoptosis  . . . . . . . . . . . . ??
               William A. Wells   Myosin V . . . . . . . . . . . . . . . . ??
               William A. Wells   A marker for munching  . . . . . . . . . ??
                   Mitch Leslie   A fatal break up . . . . . . . . . . . . ??
                   Mitch Leslie   In the nick of time  . . . . . . . . . . ??
                   Mitch Leslie   Staying connected  . . . . . . . . . . . ??
                   Mitch Leslie   To branch or not to branch . . . . . . . ??
                   Mitch Leslie   Slide this way . . . . . . . . . . . . . ??
               William A. Wells   Let's make Golgi . . . . . . . . . . . . 498
             Selin Somersan and   
                  Nina Bhardwaj   Tethering and tickling . . . . . . . . . 501
                Chuanyue Wu and   
                 Shoukat Dedhar   Integrin-linked kinase (ILK) and its
                                  interactors  . . . . . . . . . . . . . . 505
           Lisa A. Flanagan and   
                 Janet Chou and   
         Hervé Falet and   
              Ralph Neujahr and   
            John H. Hartwig and   
              Thomas P. Stossel   Filamin A, the Arp2/3 complex, and the
                                  morphology and function of cortical
                                  actin filaments in human melanoma cells  511
         Christopher L. Pin and   
       J. Michael Rukstalis and   
             Charis Johnson and   
           Stephen F. Konieczny   The bHLH transcription factor Mist1 is
                                  required to maintain exocrine pancreas
                                  cell organization and acinar cell
                                  identity . . . . . . . . . . . . . . . . 519
              Keiko Miyoshi and   
   Jonathan M. Shillingford and   
           Gilbert H. Smith and   
            Sandra L. Grimm and   
             Kay-Uwe Wagner and   
                 Takami Oka and   
           Jeffrey M. Rosen and   
       Gertraud W. Robinson and   
            Lothar Hennighausen   Signal transducer and activator of
                                  transcription (Stat) 5 controls the
                                  proliferation and differentiation of
                                  mammary alveolar epithelium  . . . . . . 531
              Suzanne Miles and   
            Heather McManus and   
        Kimberly E. Forsten and   
                  Brian Storrie   Evidence that the entire Golgi apparatus
                                  cycles in interphase HeLa cells  . . . . 543
            Theresa H. Ward and   
        Roman S. Polishchuk and   
               Steve Caplan and   
           Koret Hirschberg and   
   Jennifer Lippincott-Schwartz   Maintenance of Golgi structure and
                                  function depends on the integrity of ER
                                  export . . . . . . . . . . . . . . . . . 557
           Keisuke Tateishi and   
                Masao Omata and   
               Keiji Tanaka and   
                   Tomoki Chiba   The NEDD8 system is essential for cell
                                  cycle progression and morphogenetic
                                  pathway in mice  . . . . . . . . . . . . 571
              Joan E. Adamo and   
             John J. Moskow and   
          Amy S. Gladfelter and   
            Domenic Viterbo and   
              Daniel J. Lew and   
           Patrick J. Brennwald   Yeast Cdc42 functions at a late step in
                                  exocytosis, specifically during
                                  polarized growth of the emerging bud . . 581
             Charles Yeaman and   
         Kent K. Grindstaff and   
          Jessica R. Wright and   
                W. James Nelson   Sec6\slash 8 complexes on trans-Golgi
                                  network and plasma membrane regulate
                                  late stages of exocytosis in mammalian
                                  cells  . . . . . . . . . . . . . . . . . 593
                 Qiang Zhou and   
               Po-Hsien Chu and   
              Chenqun Huang and   
           Ching-Feng Cheng and   
         Maryann E. Martone and   
               Gudrun Knoll and   
           G. Diane Shelton and   
               Sylvia Evans and   
                        Ju Chen   Ablation of Cypher, a PDZ--LIM domain
                                  Z-line protein, causes a severe form of
                                  congenital myopathy  . . . . . . . . . . 605
Frédéric Delbac and   
         Astrid Sänger and   
             Eva M. Neuhaus and   
             Rolf Stratmann and   
            James W. Ajioka and   
          Catherine Toursel and   
    Angelika Herm-Götz and   
           Stanislas Tomavo and   
            Thierry Soldati and   
              Dominique Soldati   Toxoplasma gondii myosins B/C  . . . . . 613
           Jeffrey R. Moore and   
       Elena B. Krementsova and   
         Kathleen M. Trybus and   
               David M. Warshaw   Myosin V exhibits a high duty cycle and
                                  large unitary displacement . . . . . . . 625
               Heike Bantel and   
                Bhanu Sinha and   
           Wolfram Domschke and   
               Georg Peters and   
      Klaus Schulze-Osthoff and   
         Reiner U. Jänicke   $ \alpha $-Toxin is a mediator of
                                  Staphylococcus aureus --induced cell
                                  death and activates caspases via the
                                  intrinsic death pathway independently of
                                  death receptor signaling . . . . . . . . 637
          Peter R. Hoffmann and   
     Aimee M. deCathelineau and   
           Carol Anne Ogden and   
             Yann Leverrier and   
           Donna L. Bratton and   
            David L. Daleke and   
             Anne J. Ridley and   
           Valerie A. Fadok and   
                Peter M. Henson   Phosphatidylserine (PS) induces PS
                                  receptor--mediated macropinocytosis and
                                  promotes clearance of apoptotic cells    649
      Sabine Mechtersheimer and   
               Paul Gutwein and   
          Nancy Agmon-Levin and   
           Alexander Stoeck and   
        Matthias Oleszewski and   
              Svenja Riedle and   
               Rolf Postina and   
            Falk Fahrenholz and   
                 Mina Fogel and   
               Vance Lemmon and   
                 Peter Altevogt   Ectodomain shedding of L1 adhesion
                                  molecule promotes cell migration by
                                  autocrine binding to integrins . . . . . 661

Journal of Cell Biology
Volume 155, Number 5, November, 2001

                   Alan W. Dove   Ready \ldots set \ldots fuse . . . . . . ??
                   Alan W. Dove   Ankyrin recruits a fleet . . . . . . . . ??
                   Alan W. Dove   Heparan sulfate gets specific  . . . . . ??
                   Alan W. Dove   The leg bone's connected to the \ldots
                                  cerebellum?  . . . . . . . . . . . . . . ??
                   Alan W. Dove   Another Notch in CD44  . . . . . . . . . ??
               William A. Wells   Vpr makes holes  . . . . . . . . . . . . ??
               William A. Wells   A TORrific ATP sensor  . . . . . . . . . ??
               William A. Wells   Pinning down NuMA  . . . . . . . . . . . ??
               William A. Wells   Sigma separation . . . . . . . . . . . . ??
               William A. Wells   Surviving in low oxygen  . . . . . . . . ??
            Alexei Degterev and   
              Michael Boyce and   
                   Junying Yuan   The channel of death . . . . . . . . . . 695
       Konstantinos Meletis and   
            Jonas Frisén   Have the bloody cells gone to our heads? 699
         Peter G. Gillespie and   
         Joseph P. Albanesi and   
         Martin Bähler and   
          William M. Bement and   
           Jonathan S. Berg and   
           David R. Burgess and   
              Beth Burnside and   
          Richard E. Cheney and   
             David P. Corey and   
           Evelyne Coudrier and   
        Primal de Lanerolle and   
             John A. Hammer and   
                Tama Hasson and   
            Jeffrey R. Holt and   
             A. J. Hudspeth and   
               Mitsuo Ikebe and   
        John Kendrick-Jones and   
             Edward D. Korn and   
                    Rong Li and   
             John A. Mercer and   
         Ronald A. Milligan and   
           Mark S. Mooseker and   
           E. Michael Ostap and   
            Christine Petit and   
          Thomas D. Pollard and   
           James R. Sellers and   
            Thierry Soldati and   
              Margaret A. Titus   Myosin-I nomenclature  . . . . . . . . . 703
           Arcady Mushegian and   
               Ruslan Medzhitov   Evolutionary perspective on innate
                                  immune recognition . . . . . . . . . . . 705
              Fedor Severin and   
           Anthony A. Hyman and   
               Simonetta Piatti   Correct spindle elongation at the
                                  metaphase/anaphase transition is an
                                  APC-dependent event in budding yeast . . 711
             Berna S. Sayan and   
               Gulayse Ince and   
              A. Emre Sayan and   
                  Mehmet Ozturk   NAPO as a novel marker for apoptosis . . 719
           Evgeny V. Pavlov and   
             Muriel Priault and   
           Dawn Pietkiewicz and   
          Emily H.-Y. Cheng and   
            Bruno Antonsson and   
              Stephen Manon and   
       Stanley J. Korsmeyer and   
         Carmen A. Mannella and   
           Kathleen W. Kinnally   A novel, high conductance channel of
                                  mitochondria linked to apoptosis in
                                  mammalian cells and Bax expression in
                                  yeast  . . . . . . . . . . . . . . . . . 725
              Josef Priller and   
           Derek A. Persons and   
         Francisco F. Klett and   
            Gerd Kempermann and   
        Georg W. Kreutzberg and   
                 Ulrich Dirnagl   Neogenesis of cerebellar Purkinje
                                  neurons from gene-marked bone marrow
                                  cells in vivo  . . . . . . . . . . . . . 733
           Scott M. Jenkins and   
                   Vann Bennett   Ankyrin-G coordinates assembly of the
                                  spectrin-based membrane skeleton,
                                  voltage-gated sodium channels, and L1
                                  CAMs at Purkinje neuron initial segments 739
           Olivier Bousquet and   
                 Linglei Ma and   
            Soichiro Yamada and   
               Changhong Gu and   
             Toshihiro Idei and   
            Kenzo Takahashi and   
                Denis Wirtz and   
             Pierre A. Coulombe   The nonhelical tail domain of keratin 14
                                  promotes filament bundling and enhances
                                  the mechanical properties of keratin
                                  intermediate filaments in vitro  . . . . 747
              Isamu Okamoto and   
            Yoshiaki Kawano and   
             Daizo Murakami and   
           Takashi Sasayama and   
                Norie Araki and   
                  Toru Miki and   
             Albert J. Wong and   
                  Hideyuki Saya   Proteolytic release of CD44
                                  intracellular domain and its role in the
                                  CD44 signaling pathway . . . . . . . . . 755
             Jung-seog Kang and   
          Iain M. Cheeseman and   
           George Kallstrom and   
 Soundarapandian Velmurugan and   
            Georjana Barnes and   
            Clarence S. M. Chan   Functional cooperation of Dam1, Ipl1,
                                  and the inner centromere protein
                                  (INCENP)--related protein Sli15 during
                                  chromosome segregation . . . . . . . . . 763
    Stefan Hüttelmaier and   
        Susanne Illenberger and   
             Irina Grosheva and   
       Manfred Rüdiger and   
           Robert H. Singer and   
           Brigitte M. Jockusch   Raver1, a dual compartment protein, is a
                                  ligand for PTB/hnRNPI and microfilament
                                  attachment proteins  . . . . . . . . . . 775
      Gudrun Wahlström and   
           Maria Vartiainen and   
              Lumi Yamamoto and   
           Pieta K. Mattila and   
          Pekka Lappalainen and   
                 Tapio I. Heino   Twinfilin is required for
                                  actin-dependent developmental processes
                                  in \bionameDrosophila  . . . . . . . . . 787
         Hiroyuki Tachikawa and   
            Andrew Bloecher and   
             Kelly Tatchell and   
                Aaron M. Neiman   A Gip1p--Glc7p phosphatase complex
                                  regulates septin organization and spore
                                  wall formation . . . . . . . . . . . . . 797
            Shinichiro Taya and   
            Naoyuki Inagaki and   
            Hiroaki Sengiku and   
             Hiroshi Makino and   
           Akihiro Iwamatsu and   
              Itaru Urakawa and   
                Kenji Nagao and   
              Shiro Kataoka and   
                  Kozo Kaibuchi   Direct interaction of insulin-like
                                  growth factor-1 receptor with
                                  leukemia-associated RhoGEF . . . . . . . 809
             Martyn Chidgey and   
            Cord Brakebusch and   
           Erika Gustafsson and   
              Alan Cruchley and   
                 Chris Hail and   
                 Sarah Kirk and   
              Anita Merritt and   
               Alison North and   
             Chris Tselepis and   
                Jane Hewitt and   
              Carolyn Byrne and   
           Reinhard Fassler and   
                   David Garrod   Mice lacking desmocollin 1 show
                                  epidermal fragility accompanied by
                                  barrier defects and abnormal
                                  differentiation  . . . . . . . . . . . . 821
            Ingrid Markovic and   
            Eugenia Leikina and   
          Mikhail Zhukovsky and   
          Joshua Zimmerberg and   
         Leonid V. Chernomordik   Synchronized activation and refolding of
                                  influenza hemagglutinin in multimeric
                                  fusion machines  . . . . . . . . . . . . 833
          Benjamin L. Allen and   
              Mark S. Filla and   
              Alan C. Rapraeger   Role of heparan sulfate as a
                                  tissue-specific regulator of FGF-4 and
                                  FGF receptor recognition . . . . . . . . 845

Journal of Cell Biology
Volume 155, Number 6, December, 2001

               William A. Wells   Tmod points the way  . . . . . . . . . . ??
               William A. Wells   Peroxisomes on the move  . . . . . . . . ??
               William A. Wells   Chopping and storing in one  . . . . . . ??
               William A. Wells   Calcium-coated chromosomes . . . . . . . ??
               William A. Wells   An unfolding breast cancer story . . . . ??
                   Mitch Leslie   Freed by light . . . . . . . . . . . . . ??
                   Mitch Leslie   Going separate ways  . . . . . . . . . . ??
                   Mitch Leslie   Growing together . . . . . . . . . . . . ??
                   Mitch Leslie   A lupus explanation  . . . . . . . . . . ??
                   Mitch Leslie   Kiss of death  . . . . . . . . . . . . . ??
             Suzanne R. Pfeffer   Constructing a Golgi complex . . . . . . 873
             Benjamin Short and   
       Christian Preisinger and   
          Roman Körner and   
           Robert Kopajtich and   
                Olwyn Byron and   
                Francis A. Barr   A GRASP55-rab2 effector complex linking
                                  Golgi structure to membrane traffic  . . 877
            Francis A. Barr and   
       Christian Preisinger and   
           Robert Kopajtich and   
              Roman Körner   Golgi matrix proteins interact with p24
                                  cargo receptors and aid their efficient
                                  retention in the Golgi apparatus . . . . 885
           Rachelle Franzen and   
           Sandra L. Tanner and   
        Suzanne M. Dashiell and   
      Catherine A. Rottkamp and   
          Jeffrey A. Hammer and   
             Richard H. Quarles   Microtubule-associated protein 1B  . . . 893
              Reiner Strick and   
         Pamela L. Strissel and   
        Konstantin Gavrilov and   
            Riccardo Levi-Setti   Cation--chromatin binding as shown by
                                  ion microscopy is essential for the
                                  structural integrity of chromosomes  . . 899
                  Qinong Ye and   
                 Yan-Fen Hu and   
              Hongjun Zhong and   
                Anne C. Nye and   
          Andrew S. Belmont and   
                        Rong Li   BRCA1-induced large-scale chromatin
                                  unfolding and allele-specific effects of
                                  cancer-predisposing mutations  . . . . . 911
    Pierre-Emmanuel Gleizes and   
Jacqueline Noaillac-Depeyre and   
Isabelle Léger-Silvestre and   
Frédéric Teuli\`eres and   
          Jean-Yves Dauxois and   
               Denys Pommet and   
   Marie-Claude Azum-Gelade and   
                     Nicole Gas   Ultrastructural localization of rRNA
                                  shows defective nuclear export of
                                  preribosomes in mutants of the Nup82p
                                  complex  . . . . . . . . . . . . . . . . 923
             Mingdong Huang and   
        Jacques T. Weissman and   
Sophie Béraud-Dufour and   
                  Peng Luan and   
              Chenqian Wang and   
                   Wei Chen and   
                Meir Aridor and   
              Ian A. Wilson and   
               William E. Balch   Crystal structure of Sar1-GDP at 1.7 Å
                                  resolution and the role of the NH$_2$
                                  terminus in ER export  . . . . . . . . . 937
             Kouichi Funato and   
                 Howard Riezman   Vesicular and nonvesicular transport of
                                  ceramide from ER to the Golgi apparatus
                                  in yeast . . . . . . . . . . . . . . . . 949
            Fabienne Paumet and   
        Britta Brügger and   
          Francesco Parlati and   
             James A. McNew and   
     Thomas H. Söllner and   
               James E. Rothman   A t--SNARE of the endocytic pathway must
                                  be activated for fusion  . . . . . . . . 961
          Jason H. Brickner and   
     Jennifer M. Blanchette and   
          György Sipos and   
               Robert S. Fuller   The Tlg SNARE complex is required for
                                  TGN homotypic fusion . . . . . . . . . . 969
           Dominic Hoepfner and   
       Marlene van den Berg and   
           Peter Philippsen and   
              Henk F. Tabak and   
               Ewald H. Hettema   A role for Vps1p, actin, and the Myo2p
                                  motor in peroxisome abundance and
                                  inheritance in \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 979
                Liwen Jiang and   
         Thomas E. Phillips and   
        Christopher A. Hamm and   
      Yolanda M. Drozdowicz and   
              Philip A. Rea and   
         Masayoshi Maeshima and   
            Sally W. Rogers and   
                 John C. Rogers   The protein storage vacuole  . . . . . . 991
           Muniswamy Madesh and   
   György Hajnóczky   VDAC-dependent permeabilization of the
                                  outer mitochondrial membrane by
                                  superoxide induces rapid and massive
                                  cytochrome c release . . . . . . . . . . 1003
                  Aki Hanyu and   
           Yasuhiro Ishidou and   
           Takanori Ebisawa and   
         Tomomasa Shimanuki and   
            Takeshi Imamura and   
                 Kohei Miyazono   The N domain of Smad7 is essential for
                                  specific inhibition of transforming
                                  growth factor-$ \beta $ signaling  . . . 1017
                 Julien Cau and   
             Sandrine Faure and   
               Michel Comps and   
             Claude Delsert and   
                 Nathalie Morin   A novel p21-activated kinase binds the
                                  actin and microtubule networks and
                                  induces microtubule stabilization  . . . 1029
  Michelle Mardahl-Dumesnil and   
                Velia M. Fowler   Thin filaments elongate from their
                                  pointed ends during myofibril assembly
                                  in \bionameDrosophila indirect flight
                                  muscle . . . . . . . . . . . . . . . . . 1043
                    Wei Hsu and   
               Reena Shakya and   
               Frank Costantini   Impaired mammary gland and lymphoid
                                  development caused by inducible
                                  expression of Axin in transgenic mice    1055
          Jennifer M. Dyson and   
          Cindy J. O'Malley and   
           Jelena Becanovic and   
             Adam D. Munday and   
          Michael C. Berndt and   
          Imogen D. Coghill and   
       Harshal H. Nandurkar and   
               Lisa M. Ooms and   
          Christina A. Mitchell   The SH2-containing inositol
                                  polyphosphate $5$-phosphatase, SHIP-2,
                                  binds filamin and regulates
                                  submembraneous actin . . . . . . . . . . 1065

Journal of Cell Biology
Volume 155, Number 7, December, 2001

                   Alan W. Dove   A PHD in T cell evasion  . . . . . . . . ??
                   Alan W. Dove   Motoring through the checkpoint  . . . . ??
                   Alan W. Dove   Turning back an invasion . . . . . . . . ??
                   Alan W. Dove   Finding Rho attractive . . . . . . . . . ??
                   Alan W. Dove   Self-stimulation feels different . . . . ??
               William A. Wells   Dead cells get the squeeze . . . . . . . ??
               William A. Wells   Enter the virus  . . . . . . . . . . . . ??
               William A. Wells   Repair long and prosper  . . . . . . . . ??
               William A. Wells   Romeo and Leishmania . . . . . . . . . . ??
               William A. Wells   Making room for new memories . . . . . . ??
               William A. Wells   Connect the Nerves . . . . . . . . . . . 1096
              Hugh R. B. Pelham   Traffic through the Golgi apparatus  . . 1099
               Martin E. Hemler   Specific tetraspanin functions . . . . . 1103
                 Eva Hannak and   
            Matthew Kirkham and   
           Anthony A. Hyman and   
                   Karen Oegema   Aurora-A kinase is required for
                                  centrosome maturation in
                                  \bionameCaenorhabditis elegans . . . . . 1109
             Greg J. Bashaw and   
                  Hailan Hu and   
         Catherine D. Nobes and   
               Corey S. Goodman   A novel Dbl family RhoGEF promotes
                                  Rho-dependent axon attraction to the
                                  central nervous system midline in
                                  \bionameDrosophila and overcomes Robo
                                  repulsion  . . . . . . . . . . . . . . . 1117
           Gargi Maheshwari and   
            H. Steven Wiley and   
       Douglas A. Lauffenburger   Autocrine epidermal growth factor
                                  signaling stimulates directionally
                                  persistent mammary epithelial cell
                                  migration  . . . . . . . . . . . . . . . 1123
         Larissa Kotelevets and   
         Jolanda van Hengel and   
              Erik Bruyneel and   
                Marc Mareel and   
              Frans van Roy and   
                   Eric Chastre   The lipid phosphatase activity of PTEN
                                  is critical for stabilizing
                                  intercellular junctions and reverting
                                  invasiveness . . . . . . . . . . . . . . 1129
          Iain M. Cheeseman and   
             Christine Brew and   
           Michael Wolyniak and   
               Arshad Desai and   
             Scott Anderson and   
              Nemone Muster and   
              John R. Yates and   
            Tim C. Huffaker and   
            David G. Drubin and   
                Georjana Barnes   Implication of a novel multiprotein
                                  Dam1p complex in outer kinetochore
                                  function . . . . . . . . . . . . . . . . 1137
        Samantha G. Zeitlin and   
          Richard D. Shelby and   
              Kevin F. Sullivan   CENP-A is phosphorylated by Aurora B
                                  kinase and plays an unexpected role in
                                  completion of cytokinesis  . . . . . . . 1147
               B. J. Howell and   
               B. F. McEwen and   
               J. C. Canman and   
              D. B. Hoffman and   
               E. M. Farrar and   
               C. L. Rieder and   
                   E. D. Salmon   Cytoplasmic dynein/dynactin drives
                                  kinetochore protein transport to the
                                  spindle poles and has a role in mitotic
                                  spindle checkpoint inactivation  . . . . 1159
               Haijiang Lin and   
          Pedro de Carvalho and   
                  David Kho and   
               Chin-Yin Tai and   
            Philippe Pierre and   
             Gerald R. Fink and   
                  David Pellman   Polyploids require Bik1 for
                                  kinetochore--microtubule attachment  . . 1173
    Elizabeth E. Grevengoed and   
         Joseph J. Loureiro and   
             Traci L. Jesse and   
                    Mark Peifer   Abelson kinase regulates epithelial
                                  morphogenesis in \bionameDrosophila  . . 1185
                Joel Lanoix and   
             Joke Ouwendijk and   
               Annika Stark and   
               Edith Szafer and   
                 Dan Cassel and   
              Kurt Dejgaard and   
             Matthias Weiss and   
                  Tommy Nilsson   Sorting of Golgi resident proteins into
                                  different subpopulations of COPI
                                  vesicles . . . . . . . . . . . . . . . . 1199
José A. Martínez-Menárguez and   
             Rytis Prekeris and   
       Viola M. J. Oorschot and   
           Richard Scheller and   
                Jan W. Slot and   
              Hans J. Geuze and   
              Judith Klumperman   Peri-Golgi vesicles contain retrograde
                                  but not anterograde proteins consistent
                                  with the cisternal progression model of
                                  intra-Golgi transport  . . . . . . . . . 1213
       Alexander A. Mironov and   
     Galina V. Beznoussenko and   
            Paolo Nicoziani and   
          Oliviano Martella and   
               Alvar Trucco and   
             Hee-Seok Kweon and   
    Daniele Di Giandomenico and   
        Roman S. Polishchuk and   
             Aurora Fusella and   
             Pietro Lupetti and   
             Eric G. Berger and   
        Willie J. C. Geerts and   
          Abraham J. Koster and   
         Koert N. J. Burger and   
                  Alberto Luini   Small cargo proteins and large
                                  aggregates can traverse the Golgi by a
                                  common mechanism without leaving the
                                  lumen of cisternae . . . . . . . . . . . 1225
               Pak Phi Poon and   
         Steven F. Nothwehr and   
          Richard A. Singer and   
             Gerald C. Johnston   The Gcs1 and Age2 ArfGAP proteins
                                  provide overlapping essential function
                                  for transport from the yeast trans-Golgi
                                  network  . . . . . . . . . . . . . . . . 1239
               C. E. Futter and   
            L. M. Collinson and   
               J. M. Backer and   
                  C. R. Hopkins   Human VPS34 is required for internal
                                  vesicle formation within multivesicular
                                  endosomes  . . . . . . . . . . . . . . . 1251
             Laurent Coscoy and   
        David Jesse Sanchez and   
                      Don Ganem   A novel class of herpesvirus-encoded
                                  membrane-bound E3 ubiquitin ligases
                                  regulates endocytosis of proteins
                                  involved in immune recognition . . . . . 1265
               Marta Majdan and   
           Gregory S. Walsh and   
               Raquel Aloyz and   
                Freda D. Miller   TrkA mediates developmental sympathetic
                                  neuron survival in vivo by silencing an
                                  ongoing p75NTR-mediated death signal . . 1275
             Andreas Sander and   
            Boris A. Hesser and   
                 Veit Witzemann   MuSK induces in vivo acetylcholine
                                  receptor clusters in a
                                  ligand-independent manner  . . . . . . . 1287
            Kazuki Horikawa and   
             Masatoshi Takeichi   Requirement of the juxtamembrane domain
                                  of the cadherin cytoplasmic tail for
                                  morphogenetic cell rearrangement during
                                  myotome development  . . . . . . . . . . 1297
          Erica M. TenBroek and   
              Paul D. Lampe and   
             Joell L. Solan and   
          James K. Reynhout and   
                Ross G. Johnson   Ser364 of connexin43 and the
                                  upregulation of gap junction assembly by
                                  cAMP . . . . . . . . . . . . . . . . . . 1307
       Christoph Ballestrem and   
                 Boris Hinz and   
              Beat A. Imhof and   
         Bernhard Wehrle-Haller   Marching at the front and dragging
                                  behind . . . . . . . . . . . . . . . . . 1319
 Maria J. G. Jiménez and   
     Milagros Balbín and   
       Jesús Alvarez and   
           Toshihisa Komori and   
               Paolo Bianco and   
              Kenn Holmbeck and   
    Henning Birkedal-Hansen and   
José M. López and   
Carlos López-Otín   A regulatory cascade involving retinoic
                                  acid, Cbfa1, and matrix
                                  metalloproteinases is coupled to the
                                  development of a process of
                                  perichondrial invasion and osteogenic
                                  differentiation during bone formation    1333
            Takamasa Uekita and   
             Yoshifumi Itoh and   
                  Ikuo Yana and   
               Hiroshi Ohno and   
                 Motoharu Seiki   Cytoplasmic tail-dependent
                                  internalization of membrane-type 1
                                  matrix metalloproteinase is important
                                  for its invasion-promoting activity  . . 1345


Journal of Cell Biology
Volume 156, Number 1, January, 2002

               William A. Wells   Sticking together a signal . . . . . . . ??
               William A. Wells   Let's make liver . . . . . . . . . . . . ??
               William A. Wells   Polo meets the APC . . . . . . . . . . . ??
               William A. Wells   To Rb or not to Rb . . . . . . . . . . . ??
               William A. Wells   Squeezing for healing  . . . . . . . . . ??
                   Mitch Leslie   Greater risk from radiation? . . . . . . ??
                   Mitch Leslie   Numbers game . . . . . . . . . . . . . . ??
                   Mitch Leslie   Grow-your-own synapses . . . . . . . . . ??
                   Mitch Leslie   The good side of a maligned protein  . . ??
                   Mitch Leslie   Waltz of the chromosomes . . . . . . . . ??
              Steven S. Scherer   Myelination  . . . . . . . . . . . . . . 13
            Helge Grosshans and   
                 Frank J. Slack   Micro-RNAs . . . . . . . . . . . . . . . 17
               Karen M. May and   
            Nicola Reynolds and   
            C. Fiona Cullen and   
         Mitsuhiro Yanagida and   
                Hiroyuki Ohkura   Polo boxes and Cut23 (Apc8) mediate an
                                  interaction between polo kinase and the
                                  anaphase-promoting complex for fission
                                  yeast mitosis  . . . . . . . . . . . . . 23
       Valérie Denis and   
                Martha S. Cyert   Internal Ca$^{2+}$ release in yeast is
                                  triggered by hypertonic shock and
                                  mediated by a TRP channel homologue  . . 29
           Daniel H. Schott and   
            Ruth N. Collins and   
              Anthony Bretscher   Secretory vesicle transport velocity in
                                  living cells depends on the myosin--V
                                  lever arm length . . . . . . . . . . . . 35
                     Wei Gu and   
                   Feng Pan and   
              Honglai Zhang and   
            Gary J. Bassell and   
               Robert H. Singer   A predominantly nuclear protein
                                  affecting cytoplasmic localization of $
                                  \beta $-actin mRNA in fibroblasts and
                                  neurons  . . . . . . . . . . . . . . . . 41
          Amy M. Brownawell and   
                  Ian G. Macara   Exportin-5, a novel karyopherin,
                                  mediates nuclear export of
                                  double-stranded RNA binding proteins . . 53
           Angelika Hausser and   
                Gisela Link and   
              Linda Bamberg and   
            Annett Burzlaff and   
                 Sylke Lutz and   
          Klaus Pfizenmaier and   
           Franz-Josef Johannes   Structural requirements for localization
                                  and activation of protein kinase C $ \mu
                                  $ (PKC$ \mu $) at the Golgi compartment  65
             Khaled Machaca and   
                   Shirley Haun   Induction of maturation-promoting factor
                                  during \bionameXenopus oocyte maturation
                                  uncouples Ca$^{2+}$ store depletion from
                                  store-operated Ca$^{2+}$ entry . . . . . 75
               Toshiro Ohta and   
             Russell Essner and   
               Jung-Hwa Ryu and   
          Robert E. Palazzo and   
                Yumi Uetake and   
                 Ryoko Kuriyama   Characterization of Cep135, a novel
                                  coiled-coil centrosomal protein involved
                                  in microtubule organization in mammalian
                                  cells  . . . . . . . . . . . . . . . . . 87
              Kyoungtae Kim and   
            Thomas C. S. Keller   Smitin, a novel smooth muscle titin-like
                                  protein, interacts with myosin filaments
                                  in vivo and in vitro . . . . . . . . . . 101
           Arthur S. Rovner and   
        Patricia M. Fagnant and   
                Susan Lowey and   
             Kathleen M. Trybus   The carboxyl-terminal isoforms of smooth
                                  muscle myosin heavy chain determine
                                  thick filament assembly properties . . . 113
          Metello Innocenti and   
            Pierluigi Tenca and   
          Emanuela Frittoli and   
              Mario Faretta and   
          Arianna Tocchetti and   
        Pier Paolo Di Fiore and   
                  Giorgio Scita   Mechanisms through which Sos-1
                                  coordinates the activation of Ras and
                                  Rac  . . . . . . . . . . . . . . . . . . 125
              Enzo Calautti and   
           Maddalena Grossi and   
         Cristina Mammucari and   
                Yumi Aoyama and   
                Maria Pirro and   
              Yoshitaka Ono and   
                     Jie Li and   
                 G. Paolo Dotto   Fyn tyrosine kinase is a downstream
                                  mediator of Rho/PRK2 function in
                                  keratinocyte cell--cell adhesion . . . . 137
             Taro Matsumoto and   
            Ingela Turesson and   
                Majlis Book and   
           Pär Gerwins and   
            Lena Claesson-Welsh   p38 MAP kinase negatively regulates
                                  endothelial cell survival,
                                  proliferation, and differentiation in
                                  FGF-2--stimulated angiogenesis . . . . . 149
           Jo Ellen Feugate and   
                  QiJing Li and   
                  Lina Wong and   
          Manuela Martins-Green   The cxc chemokine cCAF stimulates
                                  differentiation of fibroblasts into
                                  myofibroblasts and accelerates wound
                                  closure  . . . . . . . . . . . . . . . . 161
             Atsushi Suzuki and   
              Yun-wen Zheng and   
                Shin Kaneko and   
           Masafumi Onodera and   
              Katashi Fukao and   
         Hiromitsu Nakauchi and   
               Hideki Taniguchi   Clonal identification and
                                  characterization of self-renewing
                                  pluripotent stem cells in the developing
                                  liver  . . . . . . . . . . . . . . . . . 173
                  Zhe Jiang and   
              Eldad Zacksenhaus   Activation of retinoblastoma protein in
                                  mammary gland leads to ductal growth
                                  suppression, precocious differentiation,
                                  and adenocarcinoma . . . . . . . . . . . 185
            M. Laura Feltri and   
          Diana Graus Porta and   
       Stefano C. Previtali and   
          Alessandro Nodari and   
        Barbara Migliavacca and   
           Arianna Cassetti and   
    Amanda Littlewood-Evans and   
         Louis F. Reichardt and   
              Albee Messing and   
           Angelo Quattrini and   
             Ulrich Mueller and   
               Lawrence Wrabetz   Conditional disruption of $ \beta $1
                                  integrin in Schwann cells impedes
                                  interactions with axons  . . . . . . . . 199

Journal of Cell Biology
Volume 156, Number 2, January, 2002

                   Alan W. Dove   It's a chaperone \ldots it's a
                                  gatekeeper \ldots it's BiP . . . . . . . ??
                   Alan W. Dove   Sorting out secretion  . . . . . . . . . ??
                   Alan W. Dove   Finding degradation at the checkpoint    ??
                   Alan W. Dove   Survival gets more complicated . . . . . ??
                   Alan W. Dove   A GTPase that goes both ways . . . . . . ??
                Rabiya Tuma and   
               William A. Wells   Cells and More Cells . . . . . . . . . . 220
             Branka Dabovic and   
                   Yan Chen and   
         Cristina Colarossi and   
               Hiroto Obata and   
              Laura Zambuto and   
             Mary Ann Perle and   
               Daniel B. Rifkin   Bone abnormalities in latent TGF-$ \beta
                                  $ binding protein (Ltbp)-3--null mice
                                  indicate a role for Ltbp-3 in modulating
                                  TGF-$ \beta $ bioavailability  . . . . . 227
             Giovanna Lalli and   
             Giampietro Schiavo   Analysis of retrograde transport in
                                  motor neurons reveals common endocytic
                                  carriers for tetanus toxin and
                                  neurotrophin receptor p75$^{\rm NTR}$    233
           Amy K. A. deHart and   
          Joshua D. Schnell and   
            Damian A. Allen and   
                    Linda Hicke   The conserved Pkh--Ypk kinase cascade is
                                  required for endocytosis in yeast  . . . 241
               Dongmin Kang and   
                 James Chen and   
                   Jim Wong and   
                    Guowei Fang   The checkpoint protein Chfr is a ligase
                                  that ubiquitinates Plk1 and inhibits
                                  Cdc2 at the G2 to M transition . . . . . 249
              Nora G. Haigh and   
              Arthur E. Johnson   A new role for BiP . . . . . . . . . . . 261
               Edina Harsay and   
                 Randy Schekman   A subset of yeast vacuolar protein
                                  sorting mutants is blocked in one branch
                                  of the exocytic pathway  . . . . . . . . 271
           Ulrich Schweizer and   
         Jennifer Gunnersen and   
            Christoph Karch and   
               Stefan Wiese and   
           Bettina Holtmann and   
             Kiyoshi Takeda and   
               Shizuo Akira and   
               Michael Sendtner   Conditional gene ablation of Stat3
                                  reveals differential signaling
                                  requirements for survival of motoneurons
                                  during development and after nerve
                                  injury in the adult  . . . . . . . . . . 287
             Elzbieta Janda and   
            Kerstin Lehmann and   
              Iris Killisch and   
          Martin Jechlinger and   
            Michaela Herzig and   
            Julian Downward and   
               Hartmut Beug and   
            Stefan Grünert   Ras and TGF$ \beta $ cooperatively
                                  regulate epithelial cell plasticity and
                                  metastasis . . . . . . . . . . . . . . . 299
          Amy S. Gladfelter and   
               Indrani Bose and   
             Trevin R. Zyla and   
        Elaine S. G. Bardes and   
                  Daniel J. Lew   Septin ring assembly involves cycles of
                                  GTP loading and hydrolysis by Cdc42p . . 315
            Andrew A. Peden and   
            Rachel E. Rudge and   
           Winnie W. Y. Lui and   
           Margaret S. Robinson   Assembly and function of AP-3 complexes
                                  in cells expressing mutant subunits  . . 327
            Masayuki Komada and   
               Philippe Soriano   $ \beta $IV-spectrin regulates sodium
                                  channel clustering through ankyrin--G at
                                  axon initial segments and nodes of
                                  Ranvier  . . . . . . . . . . . . . . . . 337
           Olga Krylyshkina and   
             Irina Kaverina and   
       Wolfgang Kranewitter and   
             Walter Steffen and   
            Maria C. Alonso and   
            Robert A. Cross and   
                J. Victor Small   Modulation of substrate adhesion
                                  dynamics via microtubule targeting
                                  requires kinesin-1 . . . . . . . . . . . 349
        Arjan van der Flier and   
             Ingrid Kuikman and   
                Duco Kramer and   
                Dirk Geerts and   
               Maaike Kreft and   
           Toshiro Takafuta and   
          Sandor S. Shapiro and   
              Arnoud Sonnenberg   Different splice variants of filamin--B
                                  affect myogenesis, subcellular
                                  distribution, and determine binding to
                                  integrin $ \beta $ subunits  . . . . . . 361
              Simona Degani and   
            Fiorella Balzac and   
            Mara Brancaccio and   
            Simona Guazzone and   
    Saverio Francesco Retta and   
            Lorenzo Silengo and   
             Alessandra Eva and   
                   Guido Tarone   The integrin cytoplasmic
                                  domain-associated protein ICAP-1 binds
                                  and regulates Rho family GTPases during
                                  cell spreading . . . . . . . . . . . . . 377
          Carien M. Niessen and   
              Barry M. Gumbiner   Cadherin-mediated cell sorting not
                                  determined by binding or adhesion
                                  specificity  . . . . . . . . . . . . . . 389

Journal of Cell Biology
Volume 156, Number 3, February, 2002

               William A. Wells   Monitoring MLCK  . . . . . . . . . . . . ??
               William A. Wells   Visualizing vesicles . . . . . . . . . . ??
               William A. Wells   With A$ \beta $, the danger lies within  ??
               William A. Wells   GRASP65 gets the chop  . . . . . . . . . ??
               William A. Wells   Building a spindle pole  . . . . . . . . ??
               William A. Wells   Cloning confusion  . . . . . . . . . . . ??
               William A. Wells   What makes Ran run?  . . . . . . . . . . ??
               William A. Wells   A JAK/STAT invasion  . . . . . . . . . . ??
               William A. Wells   The Hippi did it . . . . . . . . . . . . ??
               William A. Wells   Crossed TRAILs . . . . . . . . . . . . . ??
               Suresh Subramani   Hitchhiking fads en route to peroxisomes 415
          David E. Anderson and   
                 Ana Losada and   
         Harold P. Erickson and   
                 Tatsuya Hirano   Condensin and cohesin display different
                                  arm conformations with characteristic
                                  hinge angles . . . . . . . . . . . . . . 419
        Paula Sacco-Bubulya and   
               David L. Spector   Disassembly of interchromatin granule
                                  clusters alters the coordination of
                                  transcription and pre-mRNA splicing  . . 425
          Régis Giet and   
               Doris McLean and   
             Simon Descamps and   
             Michael J. Lee and   
             Jordan W. Raff and   
             Claude Prigent and   
                David M. Glover   Drosophila Aurora A kinase is required
                                  to localize D--TACC to centrosomes and
                                  to regulate astral microtubules  . . . . 437
         Andrea R. Castillo and   
             Janet B. Meehl and   
               Garry Morgan and   
     Amy Schutz-Geschwender and   
                     Mark Winey   The yeast protein kinase Mps1p is
                                  required for assembly of the integral
                                  spindle pole body component Spc42p . . . 453
               Jochen Huber and   
            Achim Dickmanns and   
         Reinhard Lührmann   The importin-$ \beta $ binding domain of
                                  snurportin1 is responsible for the Ran-
                                  and energy-independent nuclear import of
                                  spliceosomal U snRNPs in vitro . . . . . 467
      Vladimir I. Titorenko and   
           Jean-Marc Nicaud and   
                Huijie Wang and   
                 Honey Chan and   
         Richard A. Rachubinski   Acyl-CoA oxidase is imported as a
                                  heteropentameric, cofactor-containing
                                  complex into peroxisomes of Yarrowia
                                  lipolytica . . . . . . . . . . . . . . . 481
                Jon D. Lane and   
                John Lucocq and   
                James Pryde and   
            Francis A. Barr and   
          Philip G. Woodman and   
          Victoria J. Allan and   
                    Martin Lowe   Caspase-mediated cleavage of the
                                  stacking protein GRASP65 is required for
                                  Golgi fragmentation during apoptosis . . 495
             Pierre Barbero and   
              Lenka Bittova and   
             Suzanne R. Pfeffer   Visualization of Rab9-mediated vesicle
                                  transport from endosomes to the
                                  trans-Golgi in living cells  . . . . . . 511
                  Yan Zhang and   
         Richard McLaughlin and   
            Cynthia Goodyer and   
          Andréa LeBlanc   Selective cytotoxicity of intracellular
                                  amyloid $ \beta $ peptide$_{1 - - 42}$
                                  through p53 and Bax in cultured primary
                                  human neurons  . . . . . . . . . . . . . 519
         Pascale F. Dijkers and   
          Kim U. Birkenkamp and   
             Eric W.-F. Lam and   
         N. Shaun B. Thomas and   
      Jan-Willem J. Lammers and   
             Leo Koenderman and   
                 Paul J. Coffer   FKHR-L1 can act as a critical effector
                                  of cell death induced by cytokine
                                  withdrawal . . . . . . . . . . . . . . . 531
            Teng-Leong Chew and   
              Wendy A. Wolf and   
      Patricia J. Gallagher and   
            Fumio Matsumura and   
                Rex L. Chisholm   A fluorescent resonant energy
                                  transfer--based biosensor reveals
                                  transient and regional myosin light
                                  chain kinase activation in lamella and
                                  cleavage furrows . . . . . . . . . . . . 543
            Akira Mizoguchi and   
         Hiroyuki Nakanishi and   
             Kazushi Kimura and   
             Kaho Matsubara and   
          Kumi Ozaki-Kuroda and   
              Tatsuo Katata and   
             Tomoyuki Honda and   
         Yoshimoto Kiyohara and   
                   Kyun Heo and   
             Mikito Higashi and   
          Tomonari Tsutsumi and   
              Satomi Sonoda and   
                Chizuka Ide and   
                  Yoshimi Takai   Nectin . . . . . . . . . . . . . . . . . 555
                Jill Marcus and   
          Jeffrey L. Dupree and   
                    Brian Popko   Myelin-associated glycoprotein and
                                  myelin galactolipids stabilize
                                  developing axo-glial interactions  . . . 567

Journal of Cell Biology
Volume 156, Number 4, February, 2002

                   Alan W. Dove   The sound of one foot walking  . . . . . ??
                   Alan W. Dove   Activating actin . . . . . . . . . . . . ??
                   Alan W. Dove   Do cells have mouths?  . . . . . . . . . ??
                   Alan W. Dove   If you stretch it, they will come  . . . ??
                   Alan W. Dove   Meanwhile, back at the ring canal \ldots ??
              Nicole LeBrasseur   Sex, Sox, and splicing . . . . . . . . . ??
              Nicole LeBrasseur   Structural Mad-ness  . . . . . . . . . . ??
              Nicole LeBrasseur   Keeping the cord in place  . . . . . . . ??
              Nicole LeBrasseur   Swallowing pain relief . . . . . . . . . ??
              Nicole LeBrasseur   Collagen melt-down . . . . . . . . . . . ??
              Kathryn G. Miller   Extending the Arp2/3 complex and its
                                  regulation beyond the leading edge . . . 591
               Jomon Joseph and   
               Shyh-Han Tan and   
         Tatiana S. Karpova and   
           James G. McNally and   
                     Mary Dasso   SUMO-1 targets RanGAP1 to kinetochores
                                  and mitotic spindles . . . . . . . . . . 595
           Timothy P. Spann and   
            Anne E. Goldman and   
                  Chen Wang and   
                  Sui Huang and   
              Robert D. Goldman   Alteration of nuclear lamin organization
                                  inhibits RNA polymerase II-dependent
                                  transcription  . . . . . . . . . . . . . 603
            Yasuhiro Sawada and   
              Michael P. Sheetz   Force transduction by Triton
                                  cytoskeletons  . . . . . . . . . . . . . 609
             Phyllis Frosst and   
                Tinglu Guan and   
           Cecilia Subauste and   
                 Klaus Hahn and   
                   Larry Gerace   Tpr is localized within the nuclear
                                  basket of the pore complex and has a
                                  role in nuclear protein export . . . . . 617
               Franck Perez and   
        Karin Pernet-Gallay and   
       Clément Nizak and   
           Holly V. Goodson and   
            Thomas E. Kreis and   
                     Bruno Goud   CLIPR-59, a new trans-Golgi/TGN
                                  cytoplasmic linker protein belonging to
                                  the CLIP-170 family  . . . . . . . . . . 631
                Xiaoling Li and   
               Stephen J. Gould   PEX11 promotes peroxisome division
                                  independently of peroxisome metabolism   643
Frédéric Mallard and   
              Bor Luen Tang and   
              Thierry Galli and   
            Dani\`ele Tenza and   
          Agn\`es Saint-Pol and   
                     Xu Yue and   
              Claude Antony and   
                Wanjin Hong and   
                 Bruno Goud and   
                Ludger Johannes   Early\slash recycling endosomes--to--TGN
                                  transport involves two SNARE complexes
                                  and a Rab6 isoform . . . . . . . . . . . 653
          Francesca Santini and   
           Ibragim Gaidarov and   
                  James H. Keen   G protein--coupled receptor/arrestin3
                                  modulation of the endocytic machinery    665
           Andrew M. Hudson and   
                    Lynn Cooley   A subset of dynamic actin rearrangements
                                  in \bionameDrosophila requires the
                                  Arp2/3 complex . . . . . . . . . . . . . 677
         Jennifer A. Zallen and   
              Yehudit Cohen and   
           Andrew M. Hudson and   
                Lynn Cooley and   
             Eric Wieschaus and   
               Eyal D. Schejter   SCAR is a primary regulator of
                                  Arp2/$3$-dependent morphological events
                                  in \bionameDrosophila  . . . . . . . . . 689
              Reed J. Kelso and   
           Andrew M. Hudson and   
                    Lynn Cooley   Drosophila Kelch regulates actin
                                  organization via Src64-dependent
                                  tyrosine phosphorylation . . . . . . . . 703
            Steven P. Gross and   
           Michael A. Welte and   
            Steven M. Block and   
              Eric F. Wieschaus   Coordination of opposite-polarity
                                  microtubule motors . . . . . . . . . . . 715
              Samuel Y. Cho and   
              Richard L. Klemke   Purification of pseudopodia from
                                  polarized cells reveals redistribution
                                  and activation of Rac through assembly
                                  of a CAS/Crk scaffold  . . . . . . . . . 725
            Gerhard Schratt and   
           Ulrike Philippar and   
         Jürgen Berger and   
              Heinz Schwarz and   
           Olaf Heidenreich and   
                Alfred Nordheim   Serum response factor is crucial for
                                  actin cytoskeletal organization and
                                  focal adhesion assembly in embryonic
                                  stem cells . . . . . . . . . . . . . . . 737
           Angelika C. Paul and   
                Nadia Rosenthal   Different modes of hypertrophy in
                                  skeletal muscle fibers . . . . . . . . . 751

Journal of Cell Biology
Volume 156, Number 5, March, 2002

              Nicole LeBrasseur   The bud is all in the timing . . . . . . ??
              Nicole LeBrasseur   Shocking localization  . . . . . . . . . ??
              Nicole LeBrasseur   Actin to completion  . . . . . . . . . . ??
              Nicole LeBrasseur   A kinase kick for endocytosis  . . . . . ??
              Nicole LeBrasseur   Enabling actin . . . . . . . . . . . . . ??
               William A. Wells   One brain fits all . . . . . . . . . . . ??
               William A. Wells   Getting biorientated . . . . . . . . . . ??
               William A. Wells   Systemic destruction . . . . . . . . . . ??
               William A. Wells   Cristae in crisis  . . . . . . . . . . . ??
               William A. Wells   Put that hunchback over here . . . . . . ??
            Valerie Horsley and   
               Grace K. Pavlath   Nfat . . . . . . . . . . . . . . . . . . 771
             Caroline Jolly and   
               Lara Konecny and   
           Deborah L. Grady and   
          Yulia A. Kutskova and   
       José J. Cotto and   
        Richard I. Morimoto and   
                 Claire Vourc'h   In vivo binding of active heat shock
                                  transcription factor 1 to human
                                  chromosome 9 heterochromatin during
                                  stress . . . . . . . . . . . . . . . . . 775
             Ryoko Kuriyama and   
             Charles Gustus and   
            Yasuhiko Terada and   
                Yumi Uetake and   
              Jurgita Matuliene   CHO1, a mammalian kinesin-like protein,
                                  interacts with F-actin and is involved
                                  in the terminal phase of cytokinesis . . 783
              Doris Ricotta and   
             Sean D. Conner and   
           Sandra L. Schmid and   
            Kurt von Figura and   
             Stefan Höning   Phosphorylation of the AP2 $ \mu $
                                  subunit by AAK1 mediates high affinity
                                  binding to membrane protein sorting
                                  signals  . . . . . . . . . . . . . . . . 791
                David Sheff and   
         Laurence Pelletier and   
   Christopher B. O'Connell and   
              Graham Warren and   
                    Ira Mellman   Transferrin receptor recycling in the
                                  absence of perinuclear recycling
                                  endosomes  . . . . . . . . . . . . . . . 797
         Brigitte D. Lavoie and   
               Eileen Hogan and   
               Douglas Koshland   In vivo dissection of the chromosome
                                  condensation machinery . . . . . . . . . 805
                Anne Brunet and   
             Fumihiko Kanai and   
              Justine Stehn and   
                    Jian Xu and   
          Dilara Sarbassova and   
          John V. Frangioni and   
             Sorab N. Dalal and   
          James A. DeCaprio and   
       Michael E. Greenberg and   
               Michael B. Yaffe   14-3-3 transits to the nucleus and
                                  participates in dynamic
                                  nucleocytoplasmic transport  . . . . . . 817
         Laura R. Schenkman and   
               Carlo Caruso and   
        Nicolas Pagé and   
                John R. Pringle   The role of cell cycle--regulated
                                  expression in the localization of
                                  spatial landmark proteins in yeast . . . 829
         Karianne E. Longva and   
  Fròydis D. Blystad and   
                Espen Stang and   
           Astrid M. Larsen and   
        Lene E. Johannessen and   
               Inger H. Madshus   Ubiquitination and proteasomal activity
                                  is required for transport of the EGF
                                  receptor to inner membranes of
                                  multivesicular bodies  . . . . . . . . . 843
            Steven P. Gross and   
           M. Carolina Tuma and   
             Sean W. Deacon and   
        Anna S. Serpinskaya and   
             Amy R. Reilein and   
            Vladimir I. Gelfand   Interactions and regulation of molecular
                                  motors in \bionameXenopus melanophores   855
        Nathan R. Hutchings and   
           John E. Donelson and   
                   Kent L. Hill   Trypanin is a cytoskeletal linker
                                  protein and is required for cell
                                  motility in African trypanosomes . . . . 867
         Pamela J. Woodring and   
           E. David Litwack and   
       Dennis D. M. O'Leary and   
           Ginger R. Lucero and   
            Jean Y. J. Wang and   
                    Tony Hunter   Modulation of the F-actin cytoskeleton
                                  by c--Abl tyrosine kinase in cell
                                  spreading and neurite extension  . . . . 879
              Safedin Beqaj and   
          Sandhya Jakkaraju and   
       Raymond R. Mattingly and   
                   Desi Pan and   
                  Lucia Schuger   High RhoA activity maintains the
                                  undifferentiated mesenchymal cell
                                  phenotype, whereas RhoA down-regulation
                                  by laminin-2 induces smooth muscle
                                  myogenesis . . . . . . . . . . . . . . . 893
             Julian C. Braz and   
           Orlando F. Bueno and   
           Leon J. De Windt and   
           Jeffery D. Molkentin   PKC$ \alpha $ regulates the hypertrophic
                                  growth of cardiomyocytes through
                                  extracellular signal-regulated kinase1/2
                                  (ERK1/2) . . . . . . . . . . . . . . . . 905
             Sean D. Conner and   
               Sandra L. Schmid   Identification of an adaptor-associated
                                  kinase, AAK1, as a regulator of
                                  clathrin-mediated endocytosis  . . . . . 921

Journal of Cell Biology
Volume 156, Number 6, March, 2002

                   Alan W. Dove   Tubulin but not microtubule  . . . . . . ??
                   Alan W. Dove   Finding the dark side of tau . . . . . . ??
                   Alan W. Dove   Only one way to skin a mouse . . . . . . ??
                   Alan W. Dove   Tropomyosin keeps actin tough  . . . . . ??
                   Alan W. Dove   An acid invasion . . . . . . . . . . . . ??
              Nicole LeBrasseur   Anticancer lubrication . . . . . . . . . ??
              Nicole LeBrasseur   Coming undone at the seams . . . . . . . ??
              Nicole LeBrasseur   A trip to the ER . . . . . . . . . . . . ??
              Nicole LeBrasseur   Crumbs turns the corner  . . . . . . . . ??
              Nicole LeBrasseur   A dual purpose antideath agent . . . . . ??
            Shaynoor Dramsi and   
                Pascale Cossart   Listeriolysin O  . . . . . . . . . . . . 943
         Gianfranco Bazzoni and   
              Elisabetta Dejana   Keratinocyte junctions and the epidermal
                                  barrier  . . . . . . . . . . . . . . . . 947
               Shaun W. Lee and   
           Robert A. Bonnah and   
          Dustin L. Higashi and   
           John P. Atkinson and   
          Sharon L. Milgram and   
                   Magdalene So   CD46 is phosphorylated at tyrosine 354
                                  upon infection of epithelial cells by
                                  Neisseria gonorrhoeae  . . . . . . . . . 951
               Chin-Yin Tai and   
          Denis L. Dujardin and   
         Nicole E. Faulkner and   
              Richard B. Vallee   Role of dynein, dynactin, and CLIP-170
                                  interactions in LIS1 kinetochore
                                  function . . . . . . . . . . . . . . . . 959
            Valentina Sirri and   
 Dani\`ele Hernandez-Verdun and   
                 Pascal Roussel   Cyclin-dependent kinases govern
                                  formation and maintenance of the
                                  nucleolus  . . . . . . . . . . . . . . . 969
             Hiromichi Wada and   
              Koji Hasegawa and   
           Tatsuya Morimoto and   
            Tsuyoshi Kakita and   
         Tetsuhiko Yanazume and   
                Mitsuru Abe and   
             Shigetake Sasayama   Calcineurin-GATA-6 pathway is involved
                                  in smooth muscle-specific transcription  983
               Maureen Hyde and   
          Laura Block-Alper and   
              Jahaira Felix and   
               Paul Webster and   
                 David I. Meyer   Induction of secretory pathway
                                  components in yeast is associated with
                                  increased stability of their mRNA  . . . 993
         C. Stewart Gillmor and   
        Patricia Poindexter and   
             Justin Lorieau and   
           Monica M. Palcic and   
               Chris Somerville   $ \alpha $-Glucosidase I is required for
                                  cellulose biosynthesis and morphogenesis
                                  in Arabidopsis . . . . . . . . . . . . . 1003
     Cecilia J. Bonangelino and   
           Johnathan J. Nau and   
              Jason E. Duex and   
            Mikala Brinkman and   
          Andrew E. Wurmser and   
           Jonathan D. Gary and   
               Scott D. Emr and   
                Lois S. Weisman   Osmotic stress--induced increase of
                                  phosphatidylinositol 3,5-bisphosphate
                                  requires Vac14p, an activator of the
                                  lipid kinase Fab1p . . . . . . . . . . . 1015
             Ian J. Glomski and   
          Margaret M. Gedde and   
            Albert W. Tsang and   
            Joel A. Swanson and   
              Daniel A. Portnoy   The \bionameListeria monocytogenes
                                  hemolysin has an acidic pH optimum to
                                  compartmentalize activity and prevent
                                  damage to infected host cells  . . . . . 1029
                      Ke Hu and   
              David S. Roos and   
                 John M. Murray   A novel polymer of tubulin forms the
                                  conoid of Toxoplasma gondii  . . . . . . 1039
                  K. Stamer and   
                   R. Vogel and   
                   E. Thies and   
               E. Mandelkow and   
                E.-M. Mandelkow   Tau blocks traffic of organelles,
                                  neurofilaments, and APP vesicles in
                                  neurons and enhances oxidative stress    1051
              Shoichiro Ono and   
                     Kanako Ono   Tropomyosin inhibits
                                  ADF/cofilin-dependent actin filament
                                  dynamics . . . . . . . . . . . . . . . . 1065
        Katja C. Zimmermann and   
         Jean-Ehrland Ricci and   
          Nathalie M. Droin and   
               Douglas R. Green   The role of ARK in stress-induced
                                  apoptosis in \bionameDrosophila cells    1077
            Loretta Dorstyn and   
                Stuart Read and   
         Dimitrios Cakouros and   
                 Jun R. Huh and   
               Bruce A. Hay and   
                   Sharad Kumar   The role of cytochrome c in caspase
                                  activation in \bionameDrosophila
                                  melanogaster cells . . . . . . . . . . . 1089
               Mikio Furuse and   
                Masaki Hata and   
               Kyoko Furuse and   
               Yoko Yoshida and   
           Akinori Haratake and   
         Yoshinobu Sugitani and   
                Tetsuo Noda and   
               Akiharu Kubo and   
              Shoichiro Tsukita   Claudin-based tight junctions are
                                  crucial for the mammalian epidermal
                                  barrier  . . . . . . . . . . . . . . . . 1099


Journal of Cell Biology
Volume 157, Number 1, April, 2002

              Nicole LeBrasseur   Peroxide perturbations . . . . . . . . . ??
              Nicole LeBrasseur   Clash of the titin . . . . . . . . . . . ??
              Nicole LeBrasseur   Seeing through the cilium  . . . . . . . ??
              Nicole LeBrasseur   Topo II on the move? . . . . . . . . . . ??
              Nicole LeBrasseur   p115 SNAREs a vesicle  . . . . . . . . . ??
               William A. Wells   A BAFfling actin function  . . . . . . . ??
               William A. Wells   Sticky polarity  . . . . . . . . . . . . ??
               William A. Wells   A chemokine tug-of-war . . . . . . . . . ??
               William A. Wells   Make junction, will travel . . . . . . . ??
               William A. Wells   An ES cell caution . . . . . . . . . . . ??
               William A. Wells   Is transdifferentiation in trouble?  . . 15
       Annapaola Franchitto and   
               Pietro Pichierri   Bloom's syndrome protein is required for
                                  correct relocalization of
                                  RAD50/MRE11/NBS1 complex after
                                  replication fork arrest  . . . . . . . . 19
      Morten O. Christensen and   
           Morten K. Larsen and   
    Hans Ullrich Barthelmes and   
                Robert Hock and   
          Claus L. Andersen and   
             Eigil Kjeldsen and   
        Birgitta R. Knudsen and   
            Ole Westergaard and   
                Fritz Boege and   
               Christian Mielke   Dynamics of human DNA topoisomerases II$
                                  \alpha $ and II$ \beta $ in living cells 31
              James Shorter and   
           Matthew B. Beard and   
            Joachim Seemann and   
 A. Barbara Dirac-Svejstrup and   
                  Graham Warren   Sequential tethering of Golgins and
                                  catalysis of SNAREpin assembly by the
                                  vesicle-tethering protein p115 . . . . . 45
                  Xinmin Li and   
            Marcos P. Rivas and   
                   Min Fang and   
          Jennifer Marchena and   
            Bharat Mehrotra and   
              Anu Chaudhary and   
                    Li Feng and   
         Glenn D. Prestwich and   
             Vytas A. Bankaitis   Analysis of oxysterol binding protein
                                  homologue Kes1p function in regulation
                                  of Sec14p-dependent protein transport
                                  from the yeast Golgi complex . . . . . . 63
     Christine Boeddinghaus and   
             Alexey J. Merz and   
                 Rico Laage and   
            Christian Ungermann   A cycle of Vam7p release from and PtdIns
                                  3-P-dependent rebinding to the yeast
                                  vacuole is required for homotypic
                                  vacuole fusion . . . . . . . . . . . . . 79
               Naomi Bishop and   
            Alistair Horman and   
                 Philip Woodman   Mammalian class E vps proteins recognize
                                  ubiquitin and act in the removal of
                                  endosomal protein--ubiquitin conjugates  91
          Gregory J. Pazour and   
            Sheila A. Baker and   
             James A. Deane and   
            Douglas G. Cole and   
         Bethany L. Dickert and   
          Joel L. Rosenbaum and   
           George B. Witman and   
             Joseph C. Besharse   The intraflagellar transport protein,
                                  IFT88, is essential for vertebrate
                                  photoreceptor assembly and maintenance   103
                 John Silke and   
       Christine J. Hawkins and   
              Paul G. Ekert and   
                Joanne Chew and   
           Catherine L. Day and   
               Miha Pakusch and   
           Anne M. Verhagen and   
                  David L. Vaux   The anti-apoptotic activity of XIAP is
                                  retained upon mutation of both the
                                  caspase 3-- and caspase $9$--interacting
                                  sites  . . . . . . . . . . . . . . . . . 115
       Abigail S. McElhinny and   
            Kazumi Kakinuma and   
         Hiroyuki Sorimachi and   
           Siegfried Labeit and   
              Carol C. Gregorio   Muscle-specific RING finger-1 interacts
                                  with titin to regulate sarcomeric M-line
                                  and thick filament structure and may
                                  have nuclear functions via its
                                  interaction with glucocorticoid
                                  modulatory element binding protein-1 . . 125
        Elisabeth R. Barton and   
               Linda Morris and   
             Antonio Musaro and   
            Nadia Rosenthal and   
                 H. Lee Sweeney   Muscle-specific expression of
                                  insulin-like growth factor I counters
                                  muscle decline in mdx mice . . . . . . . 137
          Brian P. Eliceiri and   
             Xose S. Puente and   
               John D. Hood and   
          Dwayne G. Stupack and   
        David D. Schlaepfer and   
           Xiaozhu Z. Huang and   
              Dean Sheppard and   
               David A. Cheresh   Src-mediated coupling of focal adhesion
                                  kinase to integrin $ \alpha $ v $ \beta
                                  $ 5 in vascular endothelial growth
                                  factor signaling . . . . . . . . . . . . 149
             Michael H. Roh and   
              Olga Makarova and   
               Chia-Jen Liu and   
                       Shin and   
                 Seonok Lee and   
         Stephanie Laurinec and   
                Meera Goyal and   
              Roger Wiggins and   
                   Ben Margolis   The Maguk protein, Pals1, functions as
                                  an adapter, linking mammalian homologues
                                  of Crumbs and Discs Lost . . . . . . . . 161
                 Guangju Ji and   
     Christopher D. O'Brien and   
             Morris Feldman and   
             Yefim Manevich and   
                   Poay Lim and   
                   Jing Sun and   
          Steven M. Albelda and   
           Michael I. Kotlikoff   PECAM-1 (CD31) regulates a hydrogen
                                  peroxide--activated nonselective cation
                                  channel in endothelial cells . . . . . . 173

Journal of Cell Biology
Volume 157, Number 2, April, 2002

                   Alan W. Dove   Consequences of a traffic jam  . . . . . ??
                   Alan W. Dove   Utrophin gets a new look . . . . . . . . ??
                   Alan W. Dove   Knowing when to let go . . . . . . . . . ??
                   Alan W. Dove   Adapting to the pit  . . . . . . . . . . ??
                   Alan W. Dove   For healthy eyes and bones . . . . . . . ??
              Nicole LeBrasseur   Learning by palmitoylation . . . . . . . ??
              Nicole LeBrasseur   Proteases commit microbicide . . . . . . ??
              Nicole LeBrasseur   Traffic jam suppresses immunity  . . . . ??
              Nicole LeBrasseur   Pressured into making a kidney . . . . . ??
              Nicole LeBrasseur   From migration to circulation  . . . . . ??
          Iain M. Cheeseman and   
            David G. Drubin and   
                Georjana Barnes   Simple centromere, complex kinetochore   199
                Hiroki Mori and   
                  Kenneth Cline   A twin arginine signal peptide and the
                                  pH gradient trigger reversible assembly
                                  of the thylakoid $ \Delta $ pH/Tat
                                  translocase  . . . . . . . . . . . . . . 205
         Britta J. Eickholt and   
             Frank S. Walsh and   
                Patrick Doherty   An inactive pool of GSK-3 at the leading
                                  edge of growth cones is implicated in
                                  Semaphorin 3A signaling  . . . . . . . . 211
                Eric Rogers and   
             John D. Bishop and   
            James A. Waddle and   
         Jill M. Schumacher and   
                   Rueyling Lin   The aurora kinase AIR-2 functions in the
                                  release of chromosome cohesion in
                                  \bionameCaenorhabditis elegans meiosis   219
           Peter M. Carlton and   
               W. Zacheus Cande   Telomeres act autonomously in maize to
                                  organize the meiotic bouquet from a
                                  semipolarized chromosome orientation . . 231
           Vitold E. Galkin and   
              Albina Orlova and   
       Margaret S. VanLoock and   
           Inna N. Rybakova and   
           James M. Ervasti and   
              Edward H. Egelman   The utrophin actin-binding domain binds
                                  F-actin in two different modes . . . . . 243
            Martin Villalba and   
                     Kun Bi and   
                   Junru Hu and   
                Yoav Altman and   
               Paul Bushway and   
                 Eric Reits and   
            Jacques Neefjes and   
            Gottfried Baier and   
          Robert T. Abraham and   
                   Amnon Altman   Translocation of PKC$ \theta $ in T
                                  cells is mediated by a nonconventional,
                                  PI3-K- and Vav-dependent pathway, but
                                  does not absolutely require
                                  phospholipase C  . . . . . . . . . . . . 253
            Achim Obergfell and   
                   Koji Eto and   
              Attila Mocsai and   
         Charito Buensuceso and   
            Sheri L. Moores and   
             Joan S. Brugge and   
         Clifford A. Lowell and   
             Sanford J. Shattil   Coordinate interactions of Csk, Src, and
                                  Syk kinases with $ \alpha $IIb$ \beta $3
                                  initiate integrin signaling to the
                                  cytoskeleton . . . . . . . . . . . . . . 265
           Rosa Ana Lacalle and   
                Emilia Mira and   
Concepción Gómez-Moutón and   
Sonia Jiménez-Baranda and   
  Carlos Martínez-A. and   
            Santos Mañes   Specific SHP-2 partitioning in raft
                                  domains triggers integrin-mediated
                                  signaling via Rho activation . . . . . . 277
                 Yvona Ward and   
              Seow-Fong Yap and   
            V. Ravichandran and   
            Fumio Matsumura and   
                Masaaki Ito and   
              Beth Spinelli and   
                 Kathleen Kelly   The GTP binding proteins Gem and Rad are
                                  negative regulators of the Rho--Rho
                                  kinase pathway . . . . . . . . . . . . . 291
                Masaki Kato and   
            Millan S. Patel and   
            Regis Levasseur and   
                 Ivan Lobov and   
          Benny H.-J. Chang and   
            Donald A. Glass and   
         Christine Hartmann and   
                     Lan Li and   
               Tae-Ho Hwang and   
            Cory F. Brayton and   
            Richard A. Lang and   
            Gerard Karsenty and   
                  Lawrence Chan   Cbfa1-independent decrease in osteoblast
                                  proliferation, osteopenia, and
                                  persistent embryonic eye vascularization
                                  in mice deficient in Lrp5, a Wnt
                                  coreceptor . . . . . . . . . . . . . . . 303
            James P. Howard and   
            Jenna L. Hutton and   
              John M. Olson and   
               Gregory S. Payne   Sla1p serves as the targeting signal
                                  recognition factor for NPFX$_{(1, 2)}$
                                  D-mediated endocytosis . . . . . . . . . 315
              Mikael Simons and   
      Eva-Maria Krämer and   
               Paolo Macchi and   
     Silvia Rathke-Hartlieb and   
         Jacqueline Trotter and   
           Klaus-Armin Nave and   
            Jörg B. Schulz   Overexpression of the myelin proteolipid
                                  protein leads to accumulation of
                                  cholesterol and proteolipid protein in
                                  endosomes/lysosomes  . . . . . . . . . . 327

Journal of Cell Biology
Volume 157, Number 3, April, 2002

               William A. Wells   The Golgi's central COG  . . . . . . . . ??
               William A. Wells   Wnt defeats death  . . . . . . . . . . . ??
               William A. Wells   Bring in the SNAREs  . . . . . . . . . . ??
               William A. Wells   Cdc14p turns MEN on and off  . . . . . . ??
               William A. Wells   Death by autophagy . . . . . . . . . . . ??
              Nicole LeBrasseur   Ras on the inside  . . . . . . . . . . . ??
              Nicole LeBrasseur   Blood cells expand their numbers . . . . ??
              Nicole LeBrasseur   Exchange is necessary for migration  . . ??
              Nicole LeBrasseur   Suicidal yeast . . . . . . . . . . . . . ??
              Nicole LeBrasseur   A new member joins the yeast filament
                                  party  . . . . . . . . . . . . . . . . . ??
        Farrukh A. Chaudhry and   
          Richard J. Reimer and   
              Robert H. Edwards   The glutamine commute  . . . . . . . . . 349
             Lisa A. Porter and   
          Ryan W. Dellinger and   
              John A. Tynan and   
        Elizabeth A. Barnes and   
                Monica Kong and   
         Jean-Luc Lenormand and   
             Daniel J. Donoghue   Human Speedy . . . . . . . . . . . . . . 357
            Gislene Pereira and   
              Claire Manson and   
              Joan Grindlay and   
                 Elmar Schiebel   Regulation of the Bfa1p--Bub2p complex
                                  at spindle pole bodies by the cell cycle
                                  phosphatase Cdc14p . . . . . . . . . . . 367
           Judy K. VanSlyke and   
                 Linda S. Musil   Dislocation and degradation from the ER
                                  are regulated by cytosolic stress  . . . 381
                Ulrike Rein and   
                  Uwe Andag and   
               Rainer Duden and   
        Hans Dieter Schmitt and   
                     Anne Spang   ARF-GAP-mediated interaction between the
                                  ER--Golgi v--SNAREs and the COPI coat    395
               Daniel Ungar and   
              Toshihiko Oka and   
       Elizabeth E. Brittle and   
               Eliza Vasile and   
       Vladimir V. Lupashin and   
          Jon E. Chatterton and   
             John E. Heuser and   
              Monty Krieger and   
               M. Gerard Waters   Characterization of a mammalian
                                  Golgi-localized protein complex, COG,
                                  that is required for normal Golgi
                                  morphology and function  . . . . . . . . 405
          Kristina Lindsten and   
        Femke M. S. de Vrij and   
   Lisette G. G. C. Verhoef and   
           David F. Fischer and   
        Fred W. van Leeuwen and   
                Elly M. Hol and   
           Maria G. Masucci and   
                Nico P. Dantuma   Mutant ubiquitin found in
                                  neurodegenerative disorders is a
                                  ubiquitin fusion degradation substrate
                                  that blocks proteasomal degradation  . . 417
               Zongbing You and   
               Daniel Saims and   
             Shaoqiong Chen and   
            Zhaocheng Zhang and   
         Denis C. Guttridge and   
             Kun-liang Guan and   
       Ormond A. MacDougald and   
        Anthony M. C. Brown and   
                Gerard Evan and   
             Jan Kitajewski and   
                    Cun-Yu Wang   Wnt signaling promotes oncogenic
                                  transformation by inhibiting
                                  c--Myc--induced apoptosis  . . . . . . . 429
           Girish V. Putcha and   
          Charles A. Harris and   
          Krista L. Moulder and   
          Rachael M. Easton and   
          Craig B. Thompson and   
              Eugene M. Johnson   Intrinsic and extrinsic pathway
                                  signaling during neuronal apoptosis  . . 441
                 Boaz Inbal and   
               Shani Bialik and   
              Ilana Sabanay and   
                 Gidi Shani and   
                     Adi Kimchi   DAP kinase and DRP-1 mediate membrane
                                  blebbing and the formation of autophagic
                                  vesicles during programmed cell death    455
           Mireille Lambert and   
             Daniel Choquet and   
        René-Marc M\`ege   Dynamics of ligand-induced,
                                  Rac1-dependent anchoring of cadherins to
                                  the actin cytoskeleton . . . . . . . . . 469
              Emilio Hirsch and   
             Laura Barberis and   
            Mara Brancaccio and   
           Ornella Azzolino and   
                 Dazhong Xu and   
           John M. Kyriakis and   
            Lorenzo Silengo and   
       Filippo G. Giancotti and   
               Guido Tarone and   
      Reinhard Fässler and   
               Fiorella Altruda   Defective Rac-mediated proliferation and
                                  survival after targeted mutation of the
                                  $ \beta_1 $ integrin cytodomain  . . . . 481
                   Dezhi Mu and   
          Stephanie Cambier and   
        Lars Fjellbirkeland and   
              Jody L. Baron and   
             John S. Munger and   
          Hisaaki Kawakatsu and   
              Dean Sheppard and   
       V. Courtney Broaddus and   
           Stephen L. Nishimura   The integrin $ \alpha $v$ \beta $8
                                  mediates epithelial homeostasis through
                                  MT1-MMP-dependent activation of TGF-$
                                  \beta $1 . . . . . . . . . . . . . . . . 493
                 Zhuqing Li and   
           Maria J. Calzada and   
              John M. Sipes and   
             Jo Anne Cashel and   
          Henry C. Krutzsch and   
           Douglas S. Annis and   
            Deane F. Mosher and   
               David D. Roberts   Interactions of thrombospondins with $
                                  \alpha $4$ \beta $1 integrin and CD47
                                  differentially modulate T cell behavior  509
         Philipp Niethammer and   
             Markus Delling and   
            Vladimir Sytnyk and   
         Alexander Dityatev and   
              Kiyoko Fukami and   
              Melitta Schachner   Cosignaling of NCAM via lipid rafts and
                                  the FGF receptor is required for
                                  neuritogenesis . . . . . . . . . . . . . 521

Journal of Cell Biology
Volume 157, Number 4, May, 2002

                   Alan W. Dove   Turn-ons for axons . . . . . . . . . . . ??
                   Alan W. Dove   Nuclear proteins get around  . . . . . . ??
                   Alan W. Dove   Transcription in tight spaces  . . . . . ??
                   Alan W. Dove   Arresting development  . . . . . . . . . ??
                   Alan W. Dove   A muscular job for spectrin  . . . . . . ??
              Nicole LeBrasseur   Getting a GRIP on kinesin movement . . . ??
              Nicole LeBrasseur   Playing FtsZ before sporulation  . . . . ??
              Nicole LeBrasseur   Sorting it out, without clathrin . . . . ??
              Nicole LeBrasseur   Widening the target for cancer treatment ??
              Nicole LeBrasseur   Connexin the dots  . . . . . . . . . . . ??
               William A. Wells   Stop That Cell . . . . . . . . . . . . . 548
            Tarun M. Kapoor and   
               Duane A. Compton   Searching for the middle ground  . . . . 551
            Keith A. Joiner and   
                  David S. Roos   Secretory traffic in the eukaryotic
                                  parasite Toxoplasma gondii . . . . . . . 557
        Toshihide Yamashita and   
           Haruhisa Higuchi and   
                 Masaya Tohyama   The p75 receptor transduces the signal
                                  from myelin-associated glycoprotein to
                                  Rho  . . . . . . . . . . . . . . . . . . 565
             Tetsuro Tamaki and   
             Akira Akatsuka and   
               Kiyoshi Ando and   
         Yoshihiko Nakamura and   
         Hideyuki Matsuzawa and   
            Tomomitsu Hotta and   
              Roland R. Roy and   
             V. Reggie Edgerton   Identification of myogenic-endothelial
                                  progenitor cells in the interstitial
                                  spaces of skeletal muscle  . . . . . . . 571
             Nicola L. Mahy and   
              Paul E. Perry and   
            Susan Gilchrist and   
         Richard A. Baldock and   
              Wendy A. Bickmore   Spatial organization of active and
                                  inactive genes and noncoding DNA within
                                  chromosome territories . . . . . . . . . 579
                 Eva Hannak and   
               Karen Oegema and   
            Matthew Kirkham and   
         Pierre Gönczy and   
           Bianca Habermann and   
               Anthony A. Hyman   The kinetically dominant assembly
                                  pathway for centrosomal asters in
                                  \bionameCaenorhabditis elegans is $
                                  \gamma $-tubulin dependent . . . . . . . 591
        Christophe Lefebvre and   
           M. Emilie Terret and   
           Alexandre Djiane and   
          Pascale Rassinier and   
               Bernard Maro and   
  Marie-Hél\`ene Verlhac   Meiotic spindle stability depends on
                                  MAPK-interacting and spindle-stabilizing
                                  protein (MISS), a new MAPK substrate . . 603
        Anthony K. L. Leung and   
                Angus I. Lamond   In vivo analysis of NHPX reveals a novel
                                  nucleolar localization pathway involving
                                  a transient accumulation in splicing
                                  speckles . . . . . . . . . . . . . . . . 615
          Elena S. Suvorova and   
               Rainer Duden and   
           Vladimir V. Lupashin   The Sec34/Sec35p complex, a Ypt1p
                                  effector required for retrograde
                                  intra-Golgi trafficking, interacts with
                                  Golgi SNAREs and COPI vesicle coat
                                  proteins . . . . . . . . . . . . . . . . 631
               Renwang Peng and   
                Dieter Gallwitz   Sly1 protein bound to Golgi syntaxin
                                  Sed5p allows assembly and contributes to
                                  specificity of SNARE fusion complexes    645
                 Boris Hinz and   
            Giulio Gabbiani and   
           Christine Chaponnier   The NH$_2$-terminal peptide of $ \alpha
                                  $-smooth muscle actin inhibits force
                                  generation by the myofibroblast in vitro
                                  and in vivo  . . . . . . . . . . . . . . 657
          Kenneth R. Norman and   
              Donald G. Moerman   $ \alpha $ spectrin is essential for
                                  morphogenesis and body wall muscle
                                  formation in \bionameCaenorhabditis
                                  elegans  . . . . . . . . . . . . . . . . 665
                Yufang Shao and   
             Wendy Akmentin and   
      Juan Jose Toledo-Aral and   
            Julie Rosenbaum and   
            Gregorio Valdez and   
              John B. Cabot and   
           Brian S. Hilbush and   
                 Simon Halegoua   Pincher, a pinocytic chaperone for nerve
                                  growth factor/TrkA signaling endosomes   679
         Jennifer E. Morgan and   
        Jacqueline G. Gross and   
           Charles N. Pagel and   
      Jonathan R. Beauchamp and   
           Ariberto Fassati and   
         Adrian J. Thrasher and   
          James P. Di Santo and   
             Ivan B. Fisher and   
                  Xu Shiwen and   
           David J. Abraham and   
           Terence A. Partridge   Myogenic cell proliferation and
                                  generation of a reversible tumorigenic
                                  phenotype are triggered by
                                  preirradiation of the recipient site . . 693
              Bryan E. Welm and   
           Kevin W. Freeman and   
                 Mercy Chen and   
        Alejandro Contreras and   
           David M. Spencer and   
               Jeffrey M. Rosen   Inducible dimerization of FGFR1  . . . . 703
              Arie Horowitz and   
           Eugene Tkachenko and   
                 Michael Simons   Fibroblast growth factor--specific
                                  modulation of cellular response by
                                  syndecan-4 . . . . . . . . . . . . . . . 715

Journal of Cell Biology
Volume 157, Number 5, May, 2002

              Nicole LeBrasseur   Bundle loss makes turning possible . . . ??
              Nicole LeBrasseur   Blocking caspase-independent death . . . ??
              Nicole LeBrasseur   ROCK and Rho will never Dia  . . . . . . ??
              Nicole LeBrasseur   ROCK-steady centriole migration  . . . . ??
              Nicole LeBrasseur   Dynein takes its vimentin  . . . . . . . ??
               William A. Wells   How to make a helix  . . . . . . . . . . ??
               William A. Wells   Cadherins jump into the pool . . . . . . ??
               William A. Wells   A flipping permease  . . . . . . . . . . ??
               William A. Wells   Attack of the microvesicles  . . . . . . ??
               William A. Wells   The transcription--export link . . . . . ??
                      Sui Huang   Building an efficient factory  . . . . . 739
              Karel Koberna and   
 Jan Malínský and   
                Artem Pliss and   
            Martin Ma\vsata and   
Jaromíra Ve\vce\vrová and   
Markéta Fialová and   
          Jan Bednár and   
                   Ivan Ra\vska   Ribosomal genes in focus . . . . . . . . 743
              Helder Maiato and   
              Paula Sampaio and   
          Catarina L. Lemos and   
               John Findlay and   
                Mar Carmena and   
        William C. Earnshaw and   
              Claudio E. Sunkel   MAST\slash Orbit has a role in
                                  microtubule--kinetochore attachment and
                                  is essential for chromosome alignment
                                  and maintenance of spindle bipolarity    749
Carine Bossenmeyer-Pourié and   
                Rama Kannan and   
   Stéphane Ribieras and   
           Corinne Wendling and   
             Isabelle Stoll and   
                  Lars Thim and   
        Catherine Tomasetto and   
            Marie-Christine Rio   The trefoil factor 1 participates in
                                  gastrointestinal cell differentiation by
                                  delaying G1-S phase transition and
                                  reducing apoptosis . . . . . . . . . . . 761
             Louis K. Chang and   
              Eugene M. Johnson   Cyclosporin A inhibits
                                  caspase-independent death of
                                  NGF-deprived sympathetic neurons . . . . 771
               Ralf Behrens and   
                     Paul Nurse   Roles of fission yeast tea1p in the
                                  localization of polarity factors and in
                                  organizing the microtubular cytoskeleton 783
           Brian T. Helfand and   
             Atsushi Mikami and   
          Richard B. Vallee and   
              Robert D. Goldman   A requirement for cytoplasmic dynein and
                                  dynactin in intermediate filament
                                  network assembly and organization  . . . 795
  Véronique Chevrier and   
              Matthieu Piel and   
               Nora Collomb and   
             Yasmina Saoudi and   
               Ronald Frank and   
           Michel Paintrand and   
              Shuh Narumiya and   
             Michel Bornens and   
                     Didier Job   The Rho-associated protein kinase
                                  p160ROCK is required for centrosome
                                  positioning  . . . . . . . . . . . . . . 807
             Takahiro Tsuji and   
         Toshimasa Ishizaki and   
              Muneo Okamoto and   
          Chiharu Higashida and   
            Kazuhiro Kimura and   
       Tomoyuki Furuyashiki and   
            Yoshiki Arakawa and   
           Raymond B. Birge and   
           Tetsuya Nakamoto and   
             Hisamaru Hirai and   
                  Shuh Narumiya   ROCK and mDia1 antagonize in
                                  Rho-dependent Rac activation in Swiss
                                  3T3 fibroblasts  . . . . . . . . . . . . 819
            Olivier Geneste and   
           John W. Copeland and   
               Richard Treisman   LIM kinase and Diaphanous cooperate to
                                  regulate serum response factor and actin
                                  dynamics . . . . . . . . . . . . . . . . 831
             Feng-Quan Zhou and   
   Clare M. Waterman-Storer and   
           Christopher S. Cohan   Focal loss of actin bundles causes
                                  microtubule redistribution and growth
                                  cone turning . . . . . . . . . . . . . . 839
        Zhuqing Qu-Petersen and   
              Bridget Deasy and   
              Ron Jankowski and   
             Makato Ikezawa and   
              James Cummins and   
              Ryan Pruchnic and   
              John Mytinger and   
                Baohong Cao and   
              Charley Gates and   
               Anton Wernig and   
                   Johnny Huard   Identification of a novel population of
                                  muscle stem cells in mice  . . . . . . . 851
                  Hagit Niv and   
                Orit Gutman and   
                 Yoel Kloog and   
                  Yoav I. Henis   Activated K--Ras and H--Ras display
                                  different interactions with saturable
                                  nonraft sites at the surface of live
                                  cells  . . . . . . . . . . . . . . . . . 865
      Jennifer K. Sengbusch and   
                     Wei He and   
             Karen A. Pinco and   
                    Joy T. Yang   Dual functions of $ \alpha $4$ \beta $1
                                  integrin in epicardial development . . . 873
          P. Angelo Marangi and   
           Simon T. Wieland and   
               Christian Fuhrer   Laminin-1 redistributes postsynaptic
                                  proteins and requires rapsyn, tyrosine
                                  phosphorylation, and Src and Fyn to
                                  stably cluster acetylcholine receptors   883

Journal of Cell Biology
Volume 157, Number 6, June, 2002

                   Alan W. Dove   Fences catch free-ranging lipids . . . . ??
                   Alan W. Dove   Making straps from small movements . . . ??
                   Alan W. Dove   A vitamin makes minerals . . . . . . . . ??
                   Alan W. Dove   How fish oils work . . . . . . . . . . . ??
                   Alan W. Dove   A prion in yeast Huntington's disease    ??
              Nicole LeBrasseur   Getting sick from Sic  . . . . . . . . . ??
              Nicole LeBrasseur   A time for cytokinesis . . . . . . . . . ??
              Nicole LeBrasseur   How tumors escape oblivion . . . . . . . ??
              Nicole LeBrasseur   Slow and steady moves the cell . . . . . ??
              Nicole LeBrasseur   Desensitizing interactions . . . . . . . ??
          Ian Marc Bonapace and   
              Lucia Latella and   
             Roberto Papait and   
         Francesco Nicassio and   
           Alessandra Sacco and   
              Masahiro Muto and   
            Marco Crescenzi and   
            Pier Paolo Di Fiore   Np95 is regulated by E1A during mitotic
                                  reactivation of terminally
                                  differentiated cells and is essential
                                  for S phase entry  . . . . . . . . . . . 909
           Nicole R. Murray and   
              Capella Weems and   
                    Lu Chen and   
               Jessica Leon and   
               Wangsheng Yu and   
         Laurie A. Davidson and   
               Lee Jamieson and   
          Robert S. Chapkin and   
         E. Aubrey Thompson and   
                 Alan P. Fields   Protein kinase C $ \beta $II and TGF$
                                  \beta $RII in $ \omega $-3 fatty
                                  acid--mediated inhibition of colon
                                  carcinogenesis . . . . . . . . . . . . . 915
                   Min Zhao and   
                   Tian Jin and   
            Colin D. McCaig and   
          John V. Forrester and   
             Peter N. Devreotes   Genetic analysis of the role of G
                                  protein--coupled receptor signaling in
                                  electrotaxis . . . . . . . . . . . . . . 921
        Martin Offterdinger and   
     Christian Schöfer and   
       Klara Weipoltshammer and   
                Thomas W. Grunt   c-erbB-$3$ . . . . . . . . . . . . . . . 929
              Olivier Gadal and   
            Daniela Strauss and   
        Elisabeth Petfalski and   
    Pierre-Emmanuel Gleizes and   
                 Nicole Gas and   
            David Tollervey and   
                        Ed Hurt   Rlp7p is associated with 60S
                                  preribosomes, restricted to the granular
                                  component of the nucleolus, and required
                                  for pre-rRNA processing  . . . . . . . . 941
      Andrea H. Auchincloss and   
             William Zerges and   
                Karl Perron and   
   Jacqueline Girard-Bascou and   
             Jean-David Rochaix   Characterization of Tbc2, a
                                  nucleus-encoded factor specifically
                                  required for translation of the
                                  chloroplast psbC mRNA in Chlamydomonas
                                  reinhardtii  . . . . . . . . . . . . . . 953
          Eric D. Schwoebel and   
                 Thai H. Ho and   
             Mary Shannon Moore   The mechanism of inhibition of
                                  Ran-dependent nuclear transport by
                                  cellular ATP depletion . . . . . . . . . 963
             Michael Morgan and   
        Jacqueline Thorburn and   
        Pier Paolo Pandolfi and   
                Andrew Thorburn   Nuclear and cytoplasmic shuttling of
                                  TRADD induces apoptosis via different
                                  mechanisms . . . . . . . . . . . . . . . 975
         Dimitrios Cakouros and   
               Tasman Daish and   
              Damali Martin and   
          Eric H. Baehrecke and   
                   Sharad Kumar   Ecdysone-induced expression of the
                                  caspase DRONC during hormone-dependent
                                  programmed cell death in
                                  \bionameDrosophila is regulated by
                                  Broad--Complex . . . . . . . . . . . . . 985
          Anatoli B. Meriin and   
             Xiaoqian Zhang and   
                Xiangwei He and   
             Gary P. Newnam and   
           Yury O. Chernoff and   
             Michael Y. Sherman   Huntingtin toxicity in yeast model
                                  depends on polyglutamine aggregation
                                  mediated by a prion-like protein Rnq1    997
              Darinel Ortiz and   
            Martina Medkova and   
  Christiane Walch-Solimena and   
                   Peter Novick   Ypt32 recruits the Sec4p guanine
                                  nucleotide exchange factor, Sec2p, to
                                  secretory vesicles; evidence for a Rab
                                  cascade in yeast . . . . . . . . . . . . 1005
          Stephen R. Cronin and   
                 Rajini Rao and   
            Randolph Y. Hampton   Cod1p\slash Spf1p is a P-type ATPase
                                  involved in ER function and Ca$^{2+}$
                                  homeostasis  . . . . . . . . . . . . . . 1017
Anna L. Okorokova Façanha and   
           Henrik Appelgren and   
            Mohammad Tabish and   
               Lev Okorokov and   
                    Karl Ekwall   The endoplasmic reticulum cation P-type
                                  ATPase Cta4p is required for control of
                                  cell shape and microtubule dynamics  . . 1029
          Mette M. Mogensen and   
             John B. Tucker and   
             John B. Mackie and   
           Alan R. Prescott and   
            Inke S. Näthke   The adenomatous polyposis coli protein
                                  unambiguously localizes to microtubule
                                  plus ends and is involved in
                                  establishing parallel arrays of
                                  microtubule bundles in highly polarized
                                  epithelial cells . . . . . . . . . . . . 1041
                  Ming Zhao and   
          Stephen E. Harris and   
                 Diane Horn and   
                Zhaopo Geng and   
             Riko Nishimura and   
           Gregory R. Mundy and   
                        Di Chen   Bone morphogenetic protein receptor
                                  signaling is necessary for normal murine
                                  postnatal bone formation . . . . . . . . 1049
                   Wei Wang and   
                Thorsten Kirsch   Retinoic acid stimulates
                                  annexin-mediated growth plate
                                  chondrocyte mineralization . . . . . . . 1061
          Takahiro Fujiwara and   
                Ken Ritchie and   
           Hideji Murakoshi and   
               Ken Jacobson and   
                 Akihiro Kusumi   Phospholipids undergo hop diffusion in
                                  compartmentalized cell membrane  . . . . 1071
            Ravi K. Sawhney and   
                Jonathon Howard   Slow local movements of collagen fibers
                                  by fibroblasts drive the rapid global
                                  self-organization of collagen gels . . . 1083

Journal of Cell Biology
Volume 157, Number 7, June, 2002

              Nicole LeBrasseur   Prostate stem cells identified . . . . . ??
              Nicole LeBrasseur   Bundle up for cytokinesis  . . . . . . . ??
              Nicole LeBrasseur   Lon plays the chaperone  . . . . . . . . ??
              Nicole LeBrasseur   Mapping MAP binding  . . . . . . . . . . ??
              Nicole LeBrasseur   L1 sticks around . . . . . . . . . . . . ??
                    Rabiya Tuma   A Molotov cocktail . . . . . . . . . . . ??
                    Rabiya Tuma   Gluing cells into the niche  . . . . . . ??
                    Rabiya Tuma   Cajal body finds its function  . . . . . ??
                    Rabiya Tuma   And the winner is \ldots the
                                  phosphatase! . . . . . . . . . . . . . . ??
                    Rabiya Tuma   The nuclear pore as a chromatin boundary ??
          Tracey C. Dickson and   
             C. David Mintz and   
           Deanna L. Benson and   
           Stephen R. J. Salton   Functional binding interaction
                                  identified between the axonal CAM L1 and
                                  members of the ERM family  . . . . . . . 1105
          Brian P. Chadwick and   
          Huntington F. Willard   Cell cycle-dependent localization of
                                  macroH2A in chromatin of the inactive X
                                  chromosome . . . . . . . . . . . . . . . 1113
               Anja Hagting and   
           Nicole den Elzen and   
      Hartmut C. Vodermaier and   
       Irene C. Waizenegger and   
         Jan-Michael Peters and   
                 Jonathon Pines   Human securin proteolysis is controlled
                                  by the spindle checkpoint and reveals
                                  when the APC/C switches from activation
                                  by Cdc20 to Cdh1 . . . . . . . . . . . . 1125
             Jordan W. Raff and   
                Kim Jeffers and   
                 Jun-yong Huang   The roles of Fzy/Cdc20 and Fzr/Cdh1 in
                                  regulating the destruction of cyclin B
                                  in space and time  . . . . . . . . . . . 1139
                 Osamu Hori and   
             Fusae Ichinoda and   
           Takashi Tamatani and   
          Atsushi Yamaguchi and   
                 Naoya Sato and   
              Kentaro Ozawa and   
               Yasuko Kitao and   
            Mayuki Miyazaki and   
         Heather P. Harding and   
                  David Ron and   
             Masaya Tohyama and   
             David M. Stern and   
                  Satoshi Ogawa   Transmission of cell stress from
                                  endoplasmic reticulum to mitochondria    1151
    Joyce M. M. Müller and   
              James Shorter and   
             Richard Newman and   
           Katrin Deinhardt and   
                Yuval Sagiv and   
              Zvulun Elazar and   
              Graham Warren and   
                 David T. Shima   Sequential SNARE disassembly and
                                  GATE-16--GOS-28 complex assembly
                                  mediated by distinct NSF activities
                                  drives Golgi membrane fusion . . . . . . 1161
        Cristiana Mollinari and   
       Jean-Philippe Kleman and   
                  Wei Jiang and   
                Guy Schoehn and   
                Tony Hunter and   
             Robert L. Margolis   PRC1 is a microtubule binding and
                                  bundling protein essential to maintain
                                  the mitotic spindle midzone  . . . . . . 1175
           Jawdat Al-Bassam and   
             Rachel S. Ozer and   
               Daniel Safer and   
            Shelley Halpain and   
             Ronald A. Milligan   MAP2 and tau bind longitudinally along
                                  the outer ridges of microtubule
                                  protofilaments . . . . . . . . . . . . . 1187
             Pascal Steiner and   
         J.-C. Floyd Sarria and   
            Liliane Glauser and   
               Sarah Magnin and   
            Stefan Catsicas and   
                 Harald Hirling   Modulation of receptor cycling by
                                  neuron-enriched endosomal protein of 21
                                  kD . . . . . . . . . . . . . . . . . . . 1197
László Hunyady and   
           Albert J. Baukal and   
   Zsuzsanna Gáborik and   
    Jesus A. Olivares-Reyes and   
           Márta Bor and   
Márta Szaszák and   
               Robert Lodge and   
              Kevin J. Catt and   
                    Tamas Balla   Differential PI $3$-kinase dependence of
                                  early and late phases of recycling of
                                  the internalized AT$_1$ angiotensin
                                  receptor . . . . . . . . . . . . . . . . 1211
         Andrew W. Schaefer and   
            Yoshimasa Kamei and   
         Hiroyuki Kamiguchi and   
               Eric V. Wong and   
              Iris Rapoport and   
          Tomas Kirchhausen and   
             Carol M. Beach and   
              Gary Landreth and   
           Sandra K. Lemmon and   
                   Vance Lemmon   L1 endocytosis is controlled by a
                                  phosphorylation-dephosphorylation cycle
                                  stimulated by outside-in signaling by L1 1223
              Olga Barreiro and   
María Yáñez-Mó and   
           Juan M. Serrador and   
    María C. Montoya and   
  Miguel Vicente-Manzanares and   
              Reyes Tejedor and   
            Heinz Furthmayr and   
Francisco Sánchez-Madrid   Dynamic interaction of VCAM-1 and ICAM-1
                                  with moesin and ezrin in a novel
                                  endothelial docking structure for
                                  adherent leukocytes  . . . . . . . . . . 1233
               Leora Gollan and   
             Helena Sabanay and   
           Sebastian Poliak and   
           Erik O. Berglund and   
            Barbara Ranscht and   
                    Elior Peles   Retention of a cell adhesion complex at
                                  the paranodal junction requires the
                                  cytoplasmic region of Caspr  . . . . . . 1247
            Akira Tsujimura and   
           Yasuhiro Koikawa and   
                 Sarah Salm and   
              Tetsuya Takao and   
             Sandra Coetzee and   
           David Moscatelli and   
              Ellen Shapiro and   
              Herbert Lepor and   
              Tung-Tien Sun and   
              E. Lynette Wilson   Proximal location of mouse prostate
                                  epithelial stem cells  . . . . . . . . . 1257
            Donna L. Cioffi and   
           Timothy M. Moore and   
              Jerry Schaack and   
          Judy R. Creighton and   
        Dermot M. F. Cooper and   
                   Troy Stevens   Dominant regulation of interendothelial
                                  cell gap formation by calcium-inhibited
                                  type 6 adenylyl cyclase  . . . . . . . . 1267
                 Shaohua Li and   
             David Harrison and   
       Salvatore Carbonetto and   
      Reinhard Fässler and   
                 Neil Smyth and   
                David Edgar and   
             Peter D. Yurchenco   Matrix assembly, regulation, and
                                  survival functions of laminin and its
                                  receptors in embryonic stem cell
                                  differentiation  . . . . . . . . . . . . 1279


Journal of Cell Biology
Volume 158, Number 1, July, 2002

                   Alan W. Dove   The needs of the pore  . . . . . . . . . ??
                   Alan W. Dove   Only one way to organize a movement? . . ??
                   Alan W. Dove   Another way to break down  . . . . . . . ??
                   Alan W. Dove   Coordinating myosin with mitosis . . . . ??
                   Alan W. Dove   Topoisomerase gets around  . . . . . . . ??
              Nicole LeBrasseur   Bacteria tear down microtubules  . . . . ??
              Nicole LeBrasseur   Arteries play follow the leader  . . . . ??
              Nicole LeBrasseur   Stable globin needs a partner  . . . . . ??
              Nicole LeBrasseur   Ubiquitin receptor found . . . . . . . . ??
              Nicole LeBrasseur   Securin correct separation . . . . . . . ??
                Ira Mellman and   
                    Anne Ridley   Regulation and Functional Insights in
                                  Cellular Polarity Madrid, Spain June
                                  3--5, 2002 . . . . . . . . . . . . . . . 12
             Susan S. Smyth and   
                  Cam Patterson   Tiny dancers . . . . . . . . . . . . . . 17
         Penny A. Tavormina and   
    Marie-George Côme and   
           Joanna R. Hudson and   
                Yin-Yuan Mo and   
            William T. Beck and   
                Gary J. Gorbsky   Rapid exchange of mammalian
                                  topoisomerase II$ \alpha $ at
                                  kinetochores and chromosome arms in
                                  mitosis  . . . . . . . . . . . . . . . . 23
            Wendy C. Salmon and   
           Michael C. Adams and   
       Clare M. Waterman-Storer   Dual-wavelength fluorescent speckle
                                  microscopy reveals coupling of
                                  microtubule and actin movements in
                                  migrating cells  . . . . . . . . . . . . 31
           Andrea D. Weston and   
Roshantha A. S. Chandraratna and   
             Joseph Torchia and   
           T. Michael Underhill   Requirement for RAR-mediated gene
                                  repression in skeletal progenitor
                                  differentiation  . . . . . . . . . . . . 39
         Sheona P. Drummond and   
            Katherine L. Wilson   Interference with the cytoplasmic tail
                                  of gp210 disrupts ``close apposition''
                                  of nuclear membranes and blocks nuclear
                                  pore dilation  . . . . . . . . . . . . . 53
          Tobias C. Walther and   
       Helen S. Pickersgill and   
           Volker C. Cordes and   
         Martin W. Goldberg and   
             Terry D. Allen and   
             Iain W. Mattaj and   
               Maarten Fornerod   The cytoplasmic filaments of the nuclear
                                  pore complex are dispensable for
                                  selective nuclear protein import . . . . 63
                    Qi Chen and   
               Hideo Kimura and   
                 David Schubert   A novel mechanism for the regulation of
                                  amyloid precursor protein metabolism . . 79
             Cole M. Haynes and   
           Sabrina Caldwell and   
               Antony A. Cooper   An HRD /DER-independent ER quality
                                  control mechanism involves
                                  Rsp5p-dependent ubiquitination and
                                  ER--Golgi transport  . . . . . . . . . . 91
                    Jian Li and   
       Michel Pucéat and   
        Carmen Perez-Terzic and   
             Annabelle Mery and   
         Kimitoshi Nakamura and   
             Marek Michalak and   
          Karl-Heinz Krause and   
               Marisa E. Jaconi   Calreticulin reveals a critical
                                  Ca$^{2+}$ checkpoint in cardiac
                                  myofibrillogenesis . . . . . . . . . . . 103
             Raffi Gugasyan and   
              Cathy Quilici and   
            Stacey T. T. I. and   
               Dianne Grail and   
           Anne M. Verhagen and   
             Andrew Roberts and   
            Toshio Kitamura and   
             Ashley R. Dunn and   
                     Peter Lock   Dok-related protein negatively regulates
                                  T cell development via its
                                  RasGTPase-activating protein and Nck
                                  docking sites  . . . . . . . . . . . . . 115
                 Anne Royou and   
           William Sullivan and   
                   Roger Karess   Cortical recruitment of nonmuscle myosin
                                  II in early syncytial \bionameDrosophila
                                  embryos  . . . . . . . . . . . . . . . . 127
         Andrew W. Schaefer and   
                Nurul Kabir and   
                  Paul Forscher   Filopodia and actin arcs guide the
                                  assembly and transport of two
                                  populations of microtubules with unique
                                  dynamic parameters in neuronal growth
                                  cones  . . . . . . . . . . . . . . . . . 139
              Akira Katsumi and   
             Julie Milanini and   
         William B. Kiosses and   
         Miguel A. del Pozo and   
              Roland Kaunas and   
                  Shu Chien and   
              Klaus M. Hahn and   
      Martin Alexander Schwartz   Effects of cell tension on the small
                                  GTPase Rac . . . . . . . . . . . . . . . 153
                  Jun Chung and   
         Robin E. Bachelder and   
      Elizabeth A. Lipscomb and   
             Leslie M. Shaw and   
             Arthur M. Mercurio   Integrin ($ \alpha $6$ \beta $4)
                                  regulation of eIF-4E activity and VEGF
                                  translation  . . . . . . . . . . . . . . 165

Journal of Cell Biology
Volume 158, Number 2, July, 2002

                   Alan W. Dove   New tricks for old neurons . . . . . . . ??
                   Alan W. Dove   A glue for microtubule cargos  . . . . . ??
                   Alan W. Dove   Another name for autotaxin . . . . . . . ??
                   Alan W. Dove   Signaling from strange places  . . . . . ??
                   Alan W. Dove   Watching Ca$^{2+}$ waves break . . . . . ??
               William A. Wells   Plasmid segregation actin' up  . . . . . ??
               William A. Wells   Nervous chemokines . . . . . . . . . . . ??
               William A. Wells   Condensin wraps it up  . . . . . . . . . ??
               William A. Wells   Attack of the waves  . . . . . . . . . . ??
               William A. Wells   Let there be a channel . . . . . . . . . ??
            Wouter H. Moolenaar   Lysophospholipids in the limelight . . . 197
             Igor Prudovsky and   
              Cinzia Bagala and   
        Francesca Tarantini and   
             Anna Mandinova and   
            Raffaella Soldi and   
             Stephen Bellum and   
                  Thomas Maciag   The intracellular translocation of the
                                  components of the fibroblast growth
                                  factor 1 release complex precedes their
                                  assembly prior to export . . . . . . . . 201
              Gundula Rohde and   
                Dirk Wenzel and   
                  Volker Haucke   A phosphatidylinositol
                                  (4,5)-bisphosphate binding site within $
                                  \mu $2-adaptin regulates
                                  clathrin-mediated endocytosis  . . . . . 209
                Sayaka Ueno and   
           Masako Tsukamoto and   
              Tomoya Hirano and   
             Kazuya Kikuchi and   
             Maki K. Yamada and   
        Nobuyoshi Nishiyama and   
              Tetsuo Nagano and   
              Norio Matsuki and   
                   Yuji Ikegaya   Mossy fiber Zn$^{2+}$ spillover
                                  modulates heterosynaptic
                                  N-methyl-d-aspartate receptor activity
                                  in hippocampal CA3 circuits  . . . . . . 215
                 Yibing Yan and   
            Kyoko Shirakabe and   
                      Zena Werb   The metalloprotease Kuzbanian (ADAM10)
                                  mediates the transactivation of EGF
                                  receptor by G protein--coupled receptors 221
          Makiko Umezu-Goto and   
             Yasuhiro Kishi and   
               Akitsu Taira and   
                Kotaro Hama and   
              Naoshi Dohmae and   
                 Koji Takio and   
               Takao Yamori and   
            Gordon B. Mills and   
                Keizo Inoue and   
                Junken Aoki and   
                  Hiroyuki Arai   Autotaxin has lysophospholipase D
                                  activity leading to tumor cell growth
                                  and motility by lysophosphatidic acid
                                  production . . . . . . . . . . . . . . . 227
              J.-C. Bourdon and   
                 J. Renzing and   
            P. L. Robertson and   
            K. N. Fernandes and   
                     D. P. Lane   Scotin, a novel p53-inducible
                                  proapoptotic protein located in the ER
                                  and the nuclear membrane . . . . . . . . 235
          Maurizio Molinari and   
              Carmela Galli and   
           Verena Piccaluga and   
              Michel Pieren and   
                Paolo Paganetti   Sequential assistance of molecular
                                  chaperones and transient formation of
                                  covalent complexes during protein
                                  degradation from the ER  . . . . . . . . 247
          Jennifer J. Smith and   
           Marcello Marelli and   
         Rowan H. Christmas and   
      Franco J. Vizeacoumar and   
          David J. Dilworth and   
                Trey Ideker and   
           Timothy Galitski and   
           Krassen Dimitrov and   
     Richard A. Rachubinski and   
              John D. Aitchison   Transcriptome profiling to identify
                                  genes involved in peroxisome assembly
                                  and function . . . . . . . . . . . . . . 259
              Lara K. Mahal and   
          Sonia M. Sequeira and   
           Jodi M. Gureasko and   
         Thomas H. Söllner   Calcium-independent stimulation of
                                  membrane fusion and SNAREpin formation
                                  by synaptotagmin I . . . . . . . . . . . 273
           Michael C. Ashby and   
           Madeleine Craske and   
            Myoung Kyu Park and   
        Oleg V. Gerasimenko and   
         Robert D. Burgoyne and   
            Ole H. Petersen and   
              Alexei V. Tepikin   Localized Ca$^{2+}$ uncaging reveals
                                  polarized distribution of
                                  Ca$^{2+}$-sensitive Ca$^{2+}$ release
                                  sites  . . . . . . . . . . . . . . . . . 283
                    Ying Xu and   
                 Sen Takeda and   
               Takao Nakata and   
                Yasuko Noda and   
              Yosuke Tanaka and   
              Nobutaka Hirokawa   Role of KIFC3 motor protein in Golgi
                                  positioning and integration  . . . . . . 293
        Patricia S. Vaughan and   
                Pedro Miura and   
          Matthew Henderson and   
              Belinda Byrne and   
               Kevin T. Vaughan   A role for regulated binding of p150
                                  $^{\rm Glued}$ to microtubule plus ends
                                  in organelle transport . . . . . . . . . 305
            Hiroyuki Tanaka and   
        Toshihide Yamashita and   
               Minoru Asada and   
             Shuki Mizutani and   
           Hideki Yoshikawa and   
                 Masaya Tohyama   Cytoplasmic p21$^{\rm Cip1} \slash W A
                                  F1$ regulates neurite remodeling by
                                  inhibiting Rho-kinase activity . . . . . 321
           Ramanuj DasGupta and   
                Horace Rhee and   
                   Elaine Fuchs   A developmental conundrum  . . . . . . . 331
                 Mina Ryten and   
             Philip M. Dunn and   
            Joseph T. Neary and   
             Geoffrey Burnstock   ATP regulates the differentiation of
                                  mammalian skeletal muscle by activation
                                  of a P2X$_5$ receptor on satellite cells 345
               Erica Werner and   
                      Zena Werb   Integrins engage mitochondrial function
                                  for signal transduction by a mechanism
                                  dependent on Rho GTPases . . . . . . . . 357

Journal of Cell Biology
Volume 158, Number 3, August, 2002

                   Alan W. Dove   CAST into the synapse  . . . . . . . . . ??
                   Alan W. Dove   Getting trapped in a rough neighborhood  ??
                   Alan W. Dove   Two channels, one program  . . . . . . . ??
                   Alan W. Dove   BAF goes nuclear . . . . . . . . . . . . ??
                   Alan W. Dove   A new path for endostatin  . . . . . . . ??
              Nicole LeBrasseur   A molecule with a sense of timing  . . . ??
              Nicole LeBrasseur   Active cells choose life . . . . . . . . ??
              Nicole LeBrasseur   Coordination of replication  . . . . . . ??
              Nicole LeBrasseur   The ER contributes to engulfment . . . . ??
              Nicole LeBrasseur   Decoding Ca$^{2+}$ signals through cAMP  ??
          Jorge E. Galán   The cell biology of microbial infections 387
               Norma W. Andrews   Lysosomes and the plasma membrane  . . . 389
             Martin Bushell and   
                   Peter Sarnow   Hijacking the translation apparatus by
                                  RNA viruses  . . . . . . . . . . . . . . 395
                Guy R. Cornelis   Yersinia type III secretion  . . . . . . 401
          Daniel A. Portnoy and   
          Victoria Auerbuch and   
                 Ian J. Glomski   The cell biology of \bionameListeria
                                  monocytogenes infection  . . . . . . . . 409
               Craig R. Roy and   
                Lewis G. Tilney   The road less traveled . . . . . . . . . 415
           David G. Russell and   
         Henry C. Mwandumba and   
           Elizabeth E. Rhoades   Mycobacterium and the coat of many
                                  lipids . . . . . . . . . . . . . . . . . 421
              Jianqing Ding and   
                Jia-Jia Liu and   
           Anthony S. Kowal and   
            Timothy Nardine and   
      Priyanka Bhattacharya and   
                 Arthur Lee and   
                    Yanmin Yang   Microtubule-associated protein 1B  . . . 427
              Eric Rutledge and   
               Jerod Denton and   
                  Kevin Strange   Cell cycle-- and swelling-induced
                                  activation of a \bionameCaenorhabditis
                                  elegans ClC channel is mediated by
                                  CeGLC-7$ \alpha $ /$ \beta $
                                  phosphatases . . . . . . . . . . . . . . 435
               Quinton Tieu and   
            Voytek Okreglak and   
                Kari Naylor and   
                   Jodi Nunnari   The WD repeat protein, Mdv1p, functions
                                  as a molecular adaptor by interacting
                                  with Dnm1p and Fis1p during
                                  mitochondrial fission  . . . . . . . . . 445
                 M. Palmada and   
                  S. Kanwal and   
             N. J. Rutkoski and   
         C. Gustafson-Brown and   
              R. S. Johnson and   
                  R. Wisdom and   
                   B. D. Carter   c-jun is essential for sympathetic
                                  neuronal death induced by NGF withdrawal
                                  but not by p75 activation  . . . . . . . 453
      Beata Fuchsová and   
          Petr Novák and   
     Jarmila Kafková and   
             Pavel Hozák   Nuclear DNA helicase II is recruited to
                                  IFN-$ \alpha $-activated transcription
                                  sites at PML nuclear bodies  . . . . . . 463
       Miriam Segura-Totten and   
            Amy K. Kowalski and   
             Robert Craigie and   
            Katherine L. Wilson   Barrier-to-autointegration factor  . . . 475
                  Rey-Huei Chen   BubR1 is essential for kinetochore
                                  localization of other spindle checkpoint
                                  proteins and its phosphorylation
                                  requires Mad1  . . . . . . . . . . . . . 487
          Andrei V. Nikonov and   
                 Erik Snapp and   
Jennifer Lippincott-Schwartz and   
                  Gert Kreibich   Active translocon complexes labeled with
                                  GFP--Dad1 diffuse slowly as large
                                  polysome arrays in the endoplasmic
                                  reticulum  . . . . . . . . . . . . . . . 497
             Sean P. Cregan and   
               Andre Fortin and   
         Jason G. MacLaurin and   
        Steven M. Callaghan and   
          Francesco Cecconi and   
              Seong-Woon Yu and   
              Ted M. Dawson and   
           Valina L. Dawson and   
              David S. Park and   
              Guido Kroemer and   
                  Ruth S. Slack   Apoptosis-inducing factor is involved in
                                  the regulation of caspase-independent
                                  neuronal cell death  . . . . . . . . . . 507
       Amélie Robert and   
    Marie-Joëlle Miron and   
          Claudia Champagne and   
       Marie-Claude Gingras and   
          Philip E. Branton and   
         Josée N. Lavoie   Distinct cell death pathways triggered
                                  by the adenovirus early region 4 ORF 4
                                  protein  . . . . . . . . . . . . . . . . 519
             Jun-ichi Hanai and   
               Joachim Gloy and   
       S. Ananth Karumanchi and   
                Sujata Kale and   
                  Jian Tang and   
                   Guang Hu and   
                Barden Chan and   
         Ramani Ramchandran and   
                  Vivek Jha and   
          Vikas P. Sukhatme and   
                   Sergei Sokol   Endostatin is a potential inhibitor of
                                  Wnt signaling  . . . . . . . . . . . . . 529
             Akihiro Harada and   
                Junlin Teng and   
               Yosuke Takei and   
               Keiko Oguchi and   
              Nobutaka Hirokawa   MAP2 is required for dendrite
                                  elongation, PKA anchoring in dendrites,
                                  and proper PKA signal transduction . . . 541
          Christoph Kaether and   
               Sven Lammich and   
             Dieter Edbauer and   
              Michaela Ertl and   
              Jens Rietdorf and   
                Anja Capell and   
             Harald Steiner and   
                Christian Haass   Presenilin-1 affects trafficking and
                                  processing of $ \beta $APP and is
                                  targeted in a complex with nicastrin to
                                  the plasma membrane  . . . . . . . . . . 551
Sathyamangla V. Naga Prasad and   
 Stéphane A. Laporte and   
           Dean Chamberlain and   
              Marc G. Caron and   
                Larry Barak and   
              Howard A. Rockman   Phosphoinositide $3$-kinase regulates $
                                  \beta $2-adrenergic receptor endocytosis
                                  by AP-2 recruitment to the receptor/$
                                  \beta $-arrestin complex . . . . . . . . 563
          Toshihisa Ohtsuka and   
       Etsuko Takao-Rikitsu and   
                 Eiji Inoue and   
                Marie Inoue and   
          Masakazu Takeuchi and   
             Kaho Matsubara and   
      Maki Deguchi-Tawarada and   
                Keiko Satoh and   
              Koji Morimoto and   
         Hiroyuki Nakanishi and   
                  Yoshimi Takai   Cast . . . . . . . . . . . . . . . . . . 577

Journal of Cell Biology
Volume 158, Number 4, August, 2002

              Nicole LeBrasseur   Rabs make their way to mitochondria  . . ??
              Nicole LeBrasseur   Quantity assurance . . . . . . . . . . . ??
              Nicole LeBrasseur   PECAM-1 senses the pressure  . . . . . . ??
              Nicole LeBrasseur   ABU to perform under stress  . . . . . . ??
              Nicole LeBrasseur   Selectin flexible cells  . . . . . . . . ??
               William A. Wells   A mitochondrial ratchet  . . . . . . . . ??
               William A. Wells   The numbers come to light  . . . . . . . ??
               William A. Wells   Is that a fly in your leg? . . . . . . . ??
               William A. Wells   Stop and die . . . . . . . . . . . . . . ??
               William A. Wells   Brave new eggs . . . . . . . . . . . . . ??
               William A. Wells   The youth revolution . . . . . . . . . . 609
               Hudson H. Freeze   Sweet solution . . . . . . . . . . . . . 615
            Thomas A. Kufer and   
 Herman H. W. Silljé and   
          Roman Körner and   
            Oliver J. Gruss and   
            Patrick Meraldi and   
                  Erich A. Nigg   Human TPX2 is required for targeting
                                  Aurora--A kinase to the spindle  . . . . 617
              Shwetal Mehta and   
              Xian Mei Yang and   
           Clarence S. Chan and   
          Melanie J. Dobson and   
            Makkuni Jayaram and   
     Soundarapandian Velmurugan   The 2 micron plasmid purloins the yeast
                                  cohesin complex  . . . . . . . . . . . . 625
             Fumihiko Urano and   
            Marcella Calfon and   
            Takunari Yoneda and   
                    Chi Yun and   
                Moni Kiraly and   
             Scott G. Clark and   
                      David Ron   A survival pathway for
                                  \bionameCaenorhabditis elegans with a
                                  blocked unfolded protein response  . . . 639
          Björn Schwer and   
             Brian J. North and   
                Roy A. Frye and   
                Melanie Ott and   
                    Eric Verdin   The human silent information regulator
                                  (Sir)2 homologue hSIRT3 is a
                                  mitochondrial nicotinamide adenine
                                  dinucleotide-dependent deacetylase . . . 647
               Neal M. Alto and   
        Jacquelyn Soderling and   
                  John D. Scott   Rab32 is an A-kinase anchoring protein
                                  and participates in mitochondrial
                                  dynamics . . . . . . . . . . . . . . . . 659
                Gary Eitzen and   
                    Li Wang and   
            Naomi Thorngren and   
                William Wickner   Remodeling of organelle-bound actin is
                                  required for yeast vacuole fusion  . . . 669
                Mala V. Rao and   
          Michael L. Garcia and   
             Yukio Miyazaki and   
             Takahiro Gotow and   
                Aidong Yuan and   
          Salvatore Mattina and   
              Chris M. Ward and   
           Nigel A. Calcutt and   
             Yasuo Uchiyama and   
             Ralph A. Nixon and   
               Don W. Cleveland   Gene replacement in mice reveals that
                                  the heavily phosphorylated tail of
                                  neurofilament heavy subunit does not
                                  affect axonal caliber or the transit of
                                  cargoes in slow axonal transport . . . . 681
             Matthew Kofron and   
              Janet Heasman and   
          Stephanie A. Lang and   
           Christopher C. Wylie   Plakoglobin is required for maintenance
                                  of the cortical actin skeleton in early
                                  \bionameXenopus embryos and for
                                  cdc42-mediated wound healing . . . . . . 695
     Stéphane Genoud and   
       Corinna Lappe-Siefke and   
            Sandra Goebbels and   
              Freddy Radtke and   
               Michel Aguet and   
          Steven S. Scherer and   
                 Ueli Suter and   
           Klaus-Armin Nave and   
                     Ned Mantei   Notch1 control of oligodendrocyte
                                  differentiation in the spinal cord . . . 709
                J. M. Edgar and   
             T. J. Anderson and   
            P. J. Dickinson and   
               J. A. Barrie and   
            M. C. McCulloch and   
                 K.-A. Nave and   
                I. R. Griffiths   Survival of, and competition between,
                                  oligodendrocytes expressing different
                                  alleles of the Plp gene  . . . . . . . . 719
                 Rita Gallo and   
        Francesca Zazzeroni and   
             Edoardo Alesse and   
           Claudia Mincione and   
                Ugo Borello and   
            Pasquale Buanne and   
          Roberta D'Eugenio and   
           Andrew R. Mackay and   
           Beatrice Argenti and   
            Roberto Gradini and   
            Matteo A. Russo and   
            Marella Maroder and   
               Giulio Cossu and   
                Luigi Frati and   
         Isabella Screpanti and   
                 Alberto Gulino   Ren  . . . . . . . . . . . . . . . . . . 731
        Emmanuel Laplantine and   
            Ferdinand Rossi and   
               Malika Sahni and   
           Claudio Basilico and   
                 David Cobrinik   FGF signaling targets the pRb-related
                                  p107 and p130 proteins to induce
                                  chondrocyte growth arrest  . . . . . . . 741
              Thorsten Lang and   
           Martin Margittai and   
        Helmut Hölzler and   
                  Reinhard Jahn   SNAREs in native plasma membranes are
                                  active and readily form core complexes
                                  with endogenous and exogenous SNAREs . . 751
          Andrew E. Wurmser and   
                   Scott D. Emr   Novel PtdIns(3)P-binding protein Etf1
                                  functions as an effector of the Vps34
                                  PtdIns $3$-kinase in autophagy . . . . . 761
               Masaki Osawa and   
           Michitaka Masuda and   
            Ken-ichi Kusano and   
                 Keigi Fujiwara   Evidence for a role of platelet
                                  endothelial cell adhesion molecule-1 in
                                  endothelial cell mechanosignal
                                  transduction . . . . . . . . . . . . . . 773
              Tadayuki Yago and   
         Anne Leppänen and   
                Haiying Qiu and   
           Warren D. Marcus and   
        Matthias U. Nollert and   
                  Cheng Zhu and   
        Richard D. Cummings and   
               Rodger P. McEver   Distinct molecular and cellular
                                  contributions to stabilizing
                                  selectin-mediated rolling under flow . . 787
             Peter L. Smith and   
               Jay T. Myers and   
            Clare E. Rogers and   
                   Lan Zhou and   
           Bronia Petryniak and   
           Daniel J. Becker and   
      Jonathon W. Homeister and   
                   John B. Lowe   Conditional control of selectin ligand
                                  expression and global fucosylation
                                  events in mice with a targeted mutation
                                  at the FX locus  . . . . . . . . . . . . 801

Journal of Cell Biology
Volume 158, Number 5, September, 2002

                   Alan W. Dove   Protecting the ends  . . . . . . . . . . ??
                   Alan W. Dove   Less is pore . . . . . . . . . . . . . . ??
                   Alan W. Dove   A zipper designed to snag  . . . . . . . ??
                   Alan W. Dove   Crumbs under the skin  . . . . . . . . . ??
                   Alan W. Dove   Unattached kinetochore seeks short-term
                                  relationship . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Seeing in motion . . . . . . . . . . . . ??
              Nicole LeBrasseur   Traveling backward . . . . . . . . . . . ??
              Nicole LeBrasseur   When LDH says ``open,'' channels listen  ??
              Nicole LeBrasseur   Neurons are translationally smart  . . . ??
              Nicole LeBrasseur   Lipids tell channel to open wide . . . . ??
           R. C. Liddington and   
                 M. H. Ginsberg   Integrin activation takes shape  . . . . 833
            Marko J. Kallio and   
      Victoria A. Beardmore and   
        Jasminder Weinstein and   
                Gary J. Gorbsky   Rapid microtubule-independent dynamics
                                  of Cdc20 at kinetochores and centrosomes
                                  in mammalian cells . . . . . . . . . . . 841
        Jan Peter Siebrasse and   
             Elias Coutavas and   
                  Reiner Peters   Reconstitution of nuclear protein export
                                  in isolated nuclear envelopes  . . . . . 849
              Sylwia Wasiak and   
 Valerie Legendre-Guillemin and   
           Rosa Puertollano and   
   François Blondeau and   
             Martine Girard and   
           Elaine de Heuvel and   
            Daniel Boismenu and   
          Alexander W. Bell and   
         Juan S. Bonifacino and   
             Peter S. McPherson   Enthoprotin  . . . . . . . . . . . . . . 855
          Matthew P. Stokes and   
            Ruth Van Hatten and   
          Howard D. Lindsay and   
             W. Matthew Michael   DNA replication is required for the
                                  checkpoint response to damaged DNA in
                                  \bionameXenopus egg extracts . . . . . . 863
          Stephen L. Rogers and   
          Gregory C. Rogers and   
             David J. Sharp and   
                 Ronald D. Vale   Drosophila EB1 is important for proper
                                  assembly, dynamics, and positioning of
                                  the mitotic spindle  . . . . . . . . . . 873
              Eric L. Weiss and   
         Cornelia Kurischko and   
                 Chao Zhang and   
               Kevan Shokat and   
            David G. Drubin and   
                Francis C. Luca   The \bionameSaccharomyces cerevisiae
                                  Mob2p--Cbk1p kinase complex promotes
                                  polarized growth and acts with the
                                  mitotic exit network to facilitate
                                  daughter cell--specific localization of
                                  Ace2p transcription factor . . . . . . . 885
           Ulrike Gruneberg and   
            Michael Glotzer and   
              Anton Gartner and   
                  Erich A. Nigg   The CeCDC-14 phosphatase is required for
                                  cytokinesis in the
                                  \bionameCaenorhabditis elegans embryo    901
          Janet M. Cronshaw and   
      Andrew N. Krutchinsky and   
               Wenzhu Zhang and   
             Brian T. Chait and   
             Michael J. Matunis   Proteomic analysis of the mammalian
                                  nuclear pore complex . . . . . . . . . . 915
            Thomas J. Melia and   
               Thomas Weber and   
             James A. McNew and   
          Lillian E. Fisher and   
         Robert J. Johnston and   
              Frank Parlati and   
              Lara K. Mahal and   
     Thomas H. Söllner and   
               James E. Rothman   Regulation of membrane fusion by the
                                  membrane-proximal coil of the t--SNARE
                                  during zippering of SNAREpins  . . . . . 929
   Emmanuelle Médina and   
            Janice Williams and   
         Elizabeth Klipfell and   
           Daniela Zarnescu and   
              Graham Thomas and   
          André Le Bivic   Crumbs interacts with moesin and $
                                  \beta_{Heavy} $-spectrin in the apical
                                  membrane skeleton of \bionameDrosophila  941
           Sophie Charrasse and   
              Mayya Meriane and   
            Franck Comunale and   
                Anne Blangy and   
Cécile Gauthier-Rouvi\`ere   N-cadherin-dependent cell--cell contact
                                  regulates Rho GTPases and $ \beta
                                  $-catenin localization in mouse C2C12
                                  myoblasts  . . . . . . . . . . . . . . . 953
     Viyada Nunbhakdi-Craig and   
           Thomas Machleidt and   
                 Egon Ogris and   
            Dennis Bellotto and   
           Charles L. White and   
                 Estelle Sontag   Protein phosphatase 2A associates with
                                  and regulates atypical PKC and the
                                  epithelial tight junction complex  . . . 967

Journal of Cell Biology
Volume 158, Number 6, September, 2002

              Nicole LeBrasseur   Microtubules get swept up in the
                                  excitement of mitosis  . . . . . . . . . ??
              Nicole LeBrasseur   COPs are held up by Sec16p . . . . . . . ??
              Nicole LeBrasseur   Pinosomes help a virus escape  . . . . . ??
              Nicole LeBrasseur   DEDD spells death to caspase substrates  ??
              Nicole LeBrasseur   Gnawing at the bone  . . . . . . . . . . ??
               William A. Wells   Comm with me . . . . . . . . . . . . . . ??
               William A. Wells   RNAi takes on DNA  . . . . . . . . . . . ??
               William A. Wells   A titinic extension  . . . . . . . . . . ??
               William A. Wells   Channeling hedgehogs . . . . . . . . . . ??
               William A. Wells   Send Me a Message: The FASEB Conference
                                  on Signal Transduction Salt Lake City,
                                  UT June 29--July 3, 2002 . . . . . . . . 994
            Nasser M. Rusan and   
             U. Serdar Tulu and   
           Carey Fagerstrom and   
             Patricia Wadsworth   Reorganization of the microtubule array
                                  in prophase/prometaphase requires
                                  cytoplasmic dynein-dependent microtubule
                                  transport  . . . . . . . . . . . . . . . 997
François Nédélec   Computer simulations reveal motor
                                  properties generating stable
                                  antiparallel microtubule interactions    1005
             Sean P. Curran and   
       Danielle Leuenberger and   
            Einhard Schmidt and   
               Carla M. Koehler   The role of the Tim8p--Tim13p complex in
                                  a conserved import pathway for
                                  mitochondrial polytopic inner membrane
                                  proteins . . . . . . . . . . . . . . . . 1017
            Frantisek Supek and   
            David T. Madden and   
             Susan Hamamoto and   
                 Lelio Orci and   
                 Randy Schekman   Sec16p potentiates the action of COPII
                                  proteins to bud transport vesicles . . . 1029
     Hervé Le Stunff and   
        Ismael Galve-Roperh and   
          Courtney Peterson and   
           Sheldon Milstien and   
                  Sarah Spiegel   Sphingosine-1-phosphate phosphohydrolase
                                  in regulation of sphingolipid metabolism
                                  and apoptosis  . . . . . . . . . . . . . 1039
             Justine C. Lee and   
            Olaf Schickling and   
         Alexander H. Stegh and   
           Robert G. Oshima and   
             David Dinsdale and   
            Gerald M. Cohen and   
                Marcus E. Peter   DEDD regulates degradation of
                                  intermediate filaments during apoptosis  1051
            Margaret S. Lee and   
           Karen A. D'Amour and   
                 Jackie Papkoff   A yeast model system for functional
                                  analysis of $ \beta $-catenin signaling  1067
            Hans R. Widlund and   
        Martin A. Horstmann and   
            E. Roydon Price and   
                Junqing Cui and   
        Stephen L. Lessnick and   
                     Min Wu and   
                      Xi He and   
                David E. Fisher   $ \beta $-Catenin-induced melanoma
                                  growth requires the downstream target
                                  \bionameMicrophthalmia-associated
                                  transcription factor . . . . . . . . . . 1079
       Clarisse Vandebrouck and   
           Dominique Martin and   
  Monique Colson-Van Schoor and   
            Huguette Debaix and   
                Philippe Gailly   Involvement of TRPC in the abnormal
                                  calcium influx observed in dystrophic
                                  (mdx) mouse skeletal muscle fibers . . . 1089
               Yukio Hosaka and   
           Toshifumi Yokota and   
        Yuko Miyagoe-Suzuki and   
           Katsutoshi Yuasa and   
          Michihiro Imamura and   
            Ryoichi Matsuda and   
            Takaaki Ikemoto and   
              Shuhei Kameya and   
               Shin'ichi Takeda   $ \alpha $1-Syntrophin--deficient
                                  skeletal muscle exhibits hypertrophy and
                                  aberrant formation of neuromuscular
                                  junctions during regeneration  . . . . . 1097
           Jacinthe Gingras and   
             Siamak Rassadi and   
               Ellis Cooper and   
                  Michael Ferns   Agrin plays an organizing role in the
                                  formation of sympathetic synapses  . . . 1109
               Oliver Meier and   
               Karin Boucke and   
         Silvija Vig Hammer and   
             Stephan Keller and   
         Robert P. Stidwill and   
               Silvio Hemmi and   
                  Urs F. Greber   Adenovirus triggers macropinocytosis and
                                  endosomal leakage together with its
                                  clathrin-mediated uptake . . . . . . . . 1119
            Paola Spessotto and   
      Francesca Maria Rossi and   
              Massimo Degan and   
        Raffaele Di Francia and   
             Roberto Perris and   
         Alfonso Colombatti and   
                  Valter Gattei   Hyaluronan-CD44 interaction hampers
                                  migration of osteoclast-like cells by
                                  down-regulating MMP-9  . . . . . . . . . 1133

Journal of Cell Biology
Volume 158, Number 7, September, 2002

                   Mike Rossner   Figure manipulation  . . . . . . . . . . 1151
                   Alan W. Dove   Birth control for centrioles . . . . . . ??
                   Alan W. Dove   Signaling clusters caught in the act . . ??
                   Alan W. Dove   Herpes spoils excitement . . . . . . . . ??
                   Alan W. Dove   Finding a heat-shock absorber  . . . . . ??
                   Alan W. Dove   An endosomal switchboard . . . . . . . . ??
              Nicole LeBrasseur   Hiding telomerase from chromatin . . . . ??
              Nicole LeBrasseur   Semaphorins --- not just for axons . . . ??
              Nicole LeBrasseur   Promiscuous Ras turns on the wrong
                                  partner  . . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   SynCAM and sidekick synchronize synapse
                                  synthesis  . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Stand up and take hold . . . . . . . . . ??
               William A. Wells   Does size matter?  . . . . . . . . . . . 1156
                   Yali Dou and   
            Josephine Bowen and   
                  Yifan Liu and   
             Martin A. Gorovsky   Phosphorylation and an ATP-dependent
                                  process increase the dynamic exchange of
                                  H1 in chromatin  . . . . . . . . . . . . 1161
           Alexey Khodjakov and   
            Conly L. Rieder and   
          Greenfield Sluder and   
             Grisel Cassels and   
                  Ody Sibon and   
                 Chuo-Lung Wang   De novo formation of centrosomes in
                                  vertebrate cells arrested during S phase 1171
    Pascale Dupuis-Williams and   
       Anne Fleury-Aubusson and   
Nicole Garreau de Loubresse and   
   Hél\`ene Geoffroy and   
    Laurence Vayssié and   
   Angélique Galvani and   
               Aude Espigat and   
                   Jean Rossier   Functional role of $ \epsilon $-tubulin
                                  in the assembly of the centriolar
                                  microtubule scaffold . . . . . . . . . . 1183
                Yuhua Shang and   
                    Bing Li and   
             Martin A. Gorovsky   \bionameTetrahymena thermophila contains
                                  a conventional $ \gamma $-tubulin that
                                  is differentially required for the
                                  maintenance of different
                                  microtubule-organizing centers . . . . . 1195
       Thomas J. Diefenbach and   
          Vaughan M. Latham and   
              Dean Yimlamai and   
              Canwen A. Liu and   
              Ira M. Herman and   
                  Daniel G. Jay   Myosin 1c and myosin IIB serve opposing
                                  roles in lamellipodial dynamics of the
                                  neuronal growth cone . . . . . . . . . . 1207
             Gianluca Gallo and   
                 Hal F. Yee and   
             Paul C. Letourneau   Actin turnover is required to prevent
                                  axon retraction driven by endogenous
                                  actomyosin contractility . . . . . . . . 1219
              Jamil Kanaani and   
    Alaa El-Din El-Husseini and   
     Andrea Aguilera-Moreno and   
           Julia M. Diacovo and   
             David S. Bredt and   
            Steinunn Baekkeskov   A combination of three distinct
                                  trafficking signals mediates axonal
                                  targeting and presynaptic clustering of
                                  GAD65  . . . . . . . . . . . . . . . . . 1229
                Susan Hayes and   
                Anil Chawla and   
                 Silvia Corvera   TGF$ \beta $ receptor internalization
                                  into EEA1-enriched early endosomes . . . 1239
                Nina Storey and   
             David Latchman and   
                   Stuart Bevan   Selective internalization of sodium
                                  channels in rat dorsal root ganglion
                                  neurons infected with herpes simplex
                                  virus-1  . . . . . . . . . . . . . . . . 1251
         Stephen C. Bunnell and   
              David I. Hong and   
            Julia R. Kardon and   
            Tetsuo Yamazaki and   
            C. Jane McGlade and   
            Valarie A. Barr and   
           Lawrence E. Samelson   T cell receptor ligation induces the
                                  formation of dynamically regulated
                                  signaling assemblies . . . . . . . . . . 1263
              Thalia Becker and   
            F.-Ulrich Hartl and   
                  Felix Wieland   CD40, an extracellular receptor for
                                  binding and uptake of Hsp70--peptide
                                  complexes  . . . . . . . . . . . . . . . 1277
             Hongquan Zhang and   
                  Zhilun Li and   
          Eva-Karin Viklund and   
         Staffan Strömblad   p21-activated kinase 4 interacts with
                                  integrin $ \alpha $v$ \beta $5 and
                                  regulates $ \alpha $v$ \beta $5-mediated
                                  cell migration . . . . . . . . . . . . . 1287
       Alexander R. Kazarov and   
                Xiuwei Yang and   
       Christopher S. Stipp and   
              Bantoo Sehgal and   
               Martin E. Hemler   An extracellular site on tetraspanin
                                  CD151 determines $ \alpha $3 and $
                                  \alpha $6 integrin-dependent cellular
                                  morphology . . . . . . . . . . . . . . . 1299


Journal of Cell Biology
Volume 159, Number 1, October, 2002

              Nicole LeBrasseur   Calcium increases the appetite . . . . . ??
              Nicole LeBrasseur   Big proteins Ran into import
                                  difficulties . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Everyone needs a home  . . . . . . . . . ??
              Nicole LeBrasseur   Neutrophils choose the right direction   ??
              Nicole LeBrasseur   A GAP in COPI vesicle formation is
                                  filled . . . . . . . . . . . . . . . . . ??
               William A. Wells   Electrical healing . . . . . . . . . . . ??
               William A. Wells   Old and unattracted  . . . . . . . . . . ??
               William A. Wells   Adenovirus takes the back door . . . . . ??
               William A. Wells   MS as a disease of immaturity  . . . . . ??
               William A. Wells   The real role of reelin  . . . . . . . . ??
             Stephen C. Ogg and   
                Angus I. Lamond   Cajal bodies and coilin --- moving
                                  towards function . . . . . . . . . . . . 17
                Amy F. Roth and   
                  Ying Feng and   
                 Linyi Chen and   
              Nicholas G. Davis   The yeast DHHC cysteine-rich domain
                                  protein Akr1p is a palmitoyl transferase 23
               Caroline Pot and   
              Marjo Simonen and   
            Oliver Weinmann and   
               Lisa Schnell and   
           Franziska Christ and   
            Sascha Stoeckle and   
             Philipp Berger and   
        Thomas Rülicke and   
                 Ueli Suter and   
               Martin E. Schwab   Nogo-A expressed in Schwann cells
                                  impairs axonal regeneration after
                                  peripheral nerve injury  . . . . . . . . 29
   María C. de Marco and   
Fernando Martín-Belmonte and   
              Leonor Kremer and   
              Juan P. Albar and   
             Isabel Correas and   
            Jean P. Vaerman and   
    Mónica Marazuela and   
          Jennifer A. Byrne and   
               Miguel A. Alonso   MAL2, a novel raft protein of the MAL
                                  family, is an essential component of the
                                  machinery for transcytosis in hepatoma
                                  HepG2 cells  . . . . . . . . . . . . . . 37
           Maki Murata-Hori and   
                     Yu-li Wang   Both midzone and astral microtubules are
                                  involved in the delivery of cytokinesis
                                  signals  . . . . . . . . . . . . . . . . 45
             Susan K. Lyman and   
                Tinglu Guan and   
             Janna Bednenko and   
             Harald Wodrich and   
                   Larry Gerace   Influence of cargo size on Ran and
                                  energy requirements for nuclear protein
                                  import . . . . . . . . . . . . . . . . . 55
               Jia-Shu Yang and   
              Stella Y. Lee and   
               Minggeng Gao and   
           Sylvain Bourgoin and   
           Paul A. Randazzo and   
         Richard T. Premont and   
                  Victor W. Hsu   ARFGAP1 promotes the formation of COPI
                                  vesicles, suggesting function as a
                                  component of the coat  . . . . . . . . . 69
             Nicolas Vitale and   
   Sylvette Chasserot-Golaz and   
             Yannick Bailly and   
             Naoko Morinaga and   
         Michael A. Frohman and   
             Marie-France Bader   Calcium-regulated exocytosis of
                                  dense-core vesicles requires the
                                  activation of ADP-ribosylation factor
                                  (ARF)6 by ARF nucleotide binding site
                                  opener at the plasma membrane  . . . . . 79
                 Bryan Heit and   
           Samantha Tavener and   
                Eko Raharjo and   
                     Paul Kubes   An intracellular signaling hierarchy
                                  determines direction of migration in
                                  opposing chemotactic gradients . . . . . 91
                     Ti Cai and   
              Keigo Nishida and   
              Toshio Hirano and   
                Paul A. Khavari   Gab1 and SHP-2 promote Ras/MAPK
                                  regulation of epidermal growth and
                                  differentiation  . . . . . . . . . . . . 103
               Bernd Martin and   
          Richard Schneider and   
          Stefanie Janetzky and   
                Zoe Waibler and   
               Petra Pandur and   
          Michael Kühl and   
        Jürgen Behrens and   
         Klaus von der Mark and   
     Anna Starzinski-Powitz and   
                  Viktor Wixler   The LIM-only protein FHL2 interacts with
                                  $ \beta $-catenin and promotes
                                  differentiation of mouse myoblasts . . . 113
            Atsushi Asakura and   
              Patrick Seale and   
       Adele Girgis-Gabardo and   
            Michael A. Rudnicki   Myogenic specification of side
                                  population cells in skeletal muscle  . . 123
         Jeremy Skillington and   
                  Lisa Choy and   
                    Rik Derynck   Bone morphogenetic protein and retinoic
                                  acid signaling cooperate to induce
                                  osteoblast differentiation of
                                  preadipocytes  . . . . . . . . . . . . . 135
                 Toru Akune and   
               Naoshi Ogata and   
               Kazuto Hoshi and   
               Naoto Kubota and   
             Yasuo Terauchi and   
              Kazuyuki Tobe and   
              Hideko Takagi and   
             Yoshiaki Azuma and   
           Takashi Kadowaki and   
              Kozo Nakamura and   
              Hiroshi Kawaguchi   Insulin receptor substrate-2 maintains
                                  predominance of anabolic function over
                                  catabolic function of osteoblasts  . . . 147
               H. Peterziel and   
                K. Unsicker and   
                 K. Krieglstein   TGF$ \beta $ induces GDNF responsiveness
                                  in neurons by recruitment of GFR$ \alpha
                                  $1 to the plasma membrane  . . . . . . . 157
              Won-Jing Wang and   
             Jean-Cheng Kuo and   
             Chung-Chen Yao and   
                  Ruey-Hwa Chen   DAP-kinase induces apoptosis by
                                  suppressing integrin activity and
                                  disrupting matrix survival signals . . . 169
              Sharon Dewitt and   
             Maurice B. Hallett   Cytosolic free Ca$^{2+}$ changes and
                                  calpain activation are required for $
                                  \beta $ integrin--accelerated
                                  phagocytosis by human neutrophils  . . . 181

Journal of Cell Biology
Volume 159, Number 2, October, 2002

                   Alan W. Dove   A motor for neurofilaments . . . . . . . ??
                   Alan W. Dove   Initiate then elongate . . . . . . . . . ??
                   Alan W. Dove   Building the pore  . . . . . . . . . . . ??
                   Alan W. Dove   Chromosomal cliques  . . . . . . . . . . ??
                   Alan W. Dove   Gazing into the gap  . . . . . . . . . . ??
              Nicole LeBrasseur   Choose a side  . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Little PIP, little PIP, let me in  . . . ??
              Nicole LeBrasseur   Branching out requires VEGF  . . . . . . ??
              Nicole LeBrasseur   An amidation a day keeps apoptosis away  ??
              Nicole LeBrasseur   Arrested cells are Mad as Hec  . . . . . ??
             Roy L. Silverstein   The face of TSR revealed . . . . . . . . 203
                 Billy Tsai and   
                Tom A. Rapoport   Unfolded cholera toxin is transferred to
                                  the ER membrane and released from
                                  protein disulfide isomerase upon
                                  oxidation by Ero1  . . . . . . . . . . . 207
              Anja Jaeschke and   
             Joerg Hartkamp and   
               Masao Saitoh and   
              Wendy Roworth and   
          Takahiro Nobukuni and   
              Angela Hodges and   
             Julian Sampson and   
              George Thomas and   
                   Richard Lamb   Tuberous sclerosis complex tumor
                                  suppressor--mediated S6 kinase
                                  inhibition by phosphatidylinositide-3-OH
                                  kinase is mTOR independent . . . . . . . 217
          Julie M. Claycomb and   
         David M. MacAlpine and   
             James G. Evans and   
            Stephen P. Bell and   
            Terry L. Orr-Weaver   Visualization of replication initiation
                                  and elongation in \bionameDrosophila . . 225
       Michael N. Cornforth and   
     Karin M. Greulich-Bode and   
         Bradford D. Loucas and   
             Javier Arsuaga and   
      Mariel Vázquez and   
            Rainer K. Sachs and   
      Martina Brückner and   
              Michael Molls and   
           Philip Hahnfeldt and   
                Lynn Hlatky and   
               David J. Brenner   Chromosomes are predominantly located
                                  randomly with respect to each other in
                                  interphase human cells . . . . . . . . . 237
       Nicholas J. Quintyne and   
               Trina A. Schroer   Distinct cell cycle-dependent roles for
                                  dynactin and dynein at centrosomes . . . 245
       Alexander Dammermann and   
                 Andreas Merdes   Assembly of centrosomal proteins and
                                  microtubule organization depends on
                                  PCM-1  . . . . . . . . . . . . . . . . . 255
            C. Patrick Lusk and   
           Taras Makhnevych and   
           Marcello Marelli and   
          John D. Aitchison and   
             Richard W. Wozniak   Karyopherins in nuclear pore biogenesis  267
                Mala V. Rao and   
             Linda J. Engle and   
          Panaiyur S. Mohan and   
                Aidong Yuan and   
                   Dike Qiu and   
               Anne Cataldo and   
            Linda Hassinger and   
           Stephen Jacobsen and   
          Virginia M-Y. Lee and   
           Athena Andreadis and   
         Jean-Pierre Julien and   
           Paul C. Bridgman and   
                 Ralph A. Nixon   Myosin Va binding to neurofilaments is
                                  essential for correct myosin Va
                                  distribution and transport and
                                  neurofilament density  . . . . . . . . . 279
           Johannes C. Lenz and   
            H. Peter Reusch and   
            Nadine Albrecht and   
        Günter Schultz and   
               Michael Schaefer   Ca$^{2+}$-controlled competitive
                                  diacylglycerol binding of protein kinase
                                  C isoenzymes in living cells . . . . . . 291
              Yves Heremans and   
       Mark Van De Casteele and   
            Peter in't Veld and   
            Gerard Gradwohl and   
                Palle Serup and   
                 Ole Madsen and   
           Daniel Pipeleers and   
                 Harry Heimberg   Recapitulation of embryonic
                                  neuroendocrine differentiation in adult
                                  human pancreatic duct cells expressing
                                  neurogenin 3 . . . . . . . . . . . . . . 303
          Ketu Mishra-Gorur and   
            Matthew D. Rand and   
     Beatriz Perez-Villamil and   
      Spyros Artavanis-Tsakonas   Down-regulation of Delta by proteolytic
                                  processing . . . . . . . . . . . . . . . 313
             Juan Arredondo and   
           Vu Thuong Nguyen and   
   Alexander I. Chernyavsky and   
             Dani Bercovich and   
           Avi Orr-Urtreger and   
            Wolfgang Kummer and   
                Katrin Lips and   
          Douglas E. Vetter and   
               Sergei A. Grando   Central role of $ \alpha $7 nicotinic
                                  receptor in differentiation of the
                                  stratified squamous epithelium . . . . . 325
         Maëlle Jospin and   
         Vincent Jacquemond and   
     Marie-Christine Mariol and   
     Laurent Ségalat and   
                   Bruno Allard   The L-type voltage-dependent Ca$^{2+}$
                                  channel EGL-19 controls body wall muscle
                                  function in \bionameCaenorhabditis
                                  elegans  . . . . . . . . . . . . . . . . 337
             I. M. Skerrett and   
               J. Aronowitz and   
                 J. H. Shin and   
                   G. Cymes and   
                E. Kasperek and   
                  F. L. Cao and   
                B. J. Nicholson   Identification of amino acid residues
                                  lining the pore of a gap junction
                                  channel  . . . . . . . . . . . . . . . . 349
           Sebastian Poliak and   
                Sean Matlis and   
           Christoph Ullmer and   
          Steven S. Scherer and   
                    Elior Peles   Distinct claudins and associated PDZ
                                  proteins form different autotypic tight
                                  junctions in myelinating Schwann cells   361
                  Kemin Tan and   
              Mark Duquette and   
               Jin-huan Liu and   
               Yicheng Dong and   
            Rongguang Zhang and   
         Andrzej Joachimiak and   
                Jack Lawler and   
                  Jia-huai Wang   Crystal structure of the TSP-1 type 1
                                  repeats  . . . . . . . . . . . . . . . . 373

Journal of Cell Biology
Volume 159, Number 3, November, 2002

              Nicole LeBrasseur   cGMP steers axons home . . . . . . . . . ??
              Nicole LeBrasseur   ECM communicates with MMP  . . . . . . . ??
              Nicole LeBrasseur   E-Cadherin in a stabilizing relationship ??
              Nicole LeBrasseur   Tension seals axons fate . . . . . . . . ??
              Nicole LeBrasseur   Ribosomes pile up  . . . . . . . . . . . ??
               William A. Wells   Flicking the chromosome--attachment
                                  switch . . . . . . . . . . . . . . . . . ??
               William A. Wells   Repressing differentiation . . . . . . . ??
               William A. Wells   Switch to survival . . . . . . . . . . . ??
               William A. Wells   An unlikely culprit in prion diseases    ??
               William A. Wells   Transcriptional segregation  . . . . . . ??
                   Beate Sodeik   Unchain my heart, baby let me go --- the
                                  entry and intracellular transport of HIV 393
          Svetlana Rashkova and   
             Sarah E. Karam and   
             Rebecca Kellum and   
                Mary-Lou Pardue   Gag proteins of the two
                                  \bionameDrosophila telomeric
                                  retrotransposons are targeted to
                                  chromosome ends  . . . . . . . . . . . . 397
         Anat A. Herskovits and   
               Eyal Shimoni and   
             Abraham Minsky and   
                     Eitan Bibi   Accumulation of endoplasmic membranes
                                  and novel membrane-bound
                                  ribosome--signal recognition particle
                                  receptor complexes in
                                  \bionameEscherichia coli . . . . . . . . 403
             Joan C. Politz and   
       Laura B. Lewandowski and   
                 Thoru Pederson   Signal recognition particle RNA
                                  localization within the nucleolus
                                  differs from the classical sites of
                                  ribosome synthesis . . . . . . . . . . . 411
           Jeffrey D. Amack and   
          Shannon R. Reagan and   
              Mani S. Mahadevan   Mutant DMPK 3'-UTR transcripts disrupt
                                  C2C12 myogenic differentiation by
                                  compromising MyoD  . . . . . . . . . . . 419
                   Jun Yang and   
               Xiaoqing Liu and   
                 Guohua Yue and   
            Michael Adamian and   
              Oleg Bulgakov and   
                     Tiansen Li   Rootletin, a novel coiled-coil protein,
                                  is a structural component of the ciliary
                                  rootlet  . . . . . . . . . . . . . . . . 431
             David McDonald and   
           Marie A. Vodicka and   
              Ginger Lucero and   
        Tatyana M. Svitkina and   
             Gary G. Borisy and   
            Michael Emerman and   
                 Thomas J. Hope   Visualization of the intracellular
                                  behavior of HIV in living cells  . . . . 441
        Marie-Ange Deugnier and   
          Marisa M. Faraldo and   
               Bassam Janji and   
         Patricia Rousselle and   
           Jean Paul Thiery and   
             Marina A. Glukhova   EGF controls the in vivo developmental
                                  potential of a mammary epithelial cell
                                  line possessing progenitor properties    453
     Reneé C. Ireton and   
           Michael A. Davis and   
         Jolanda van Hengel and   
         Deborah J. Mariner and   
                Kirk Barnes and   
          Molly A. Thoreson and   
      Panos Z. Anastasiadis and   
           Linsey Matrisian and   
             Linda M. Bundy and   
                Linda Sealy and   
            Barbara Gilbert and   
              Frans van Roy and   
             Albert B. Reynolds   A novel role for p120 catenin in
                                  E-cadherin function  . . . . . . . . . . 465
             Henry C. Chang and   
          Sherri L. Newmyer and   
            Michael J. Hull and   
           Melanie Ebersold and   
           Sandra L. Schmid and   
                    Ira Mellman   Hsc70 is required for endocytosis and
                                  clathrin function in \bionameDrosophila  477
             Hannes Schmidt and   
            Matthias Werner and   
        Paul A. Heppenstall and   
          Mechthild Henning and   
     Margret I. Moré and   
    Susanne Kühbandner and   
              Gary R. Lewin and   
              Franz Hofmann and   
                Robert Feil and   
               Fritz G. Rathjen   cGMP-mediated signaling via cGKI$ \alpha
                                  $ is required for the guidance and
                                  connectivity of sensory axons  . . . . . 489
          Phillip Lamoureux and   
              Gordon Ruthel and   
          Robert E. Buxbaum and   
            Steven R. Heidemann   Mechanical tension can specify axonal
                                  fate in hippocampal neurons  . . . . . . 499
   Beatriz G. Gálvez and   
Salomón Matías-Román and   
María Yáñez-Mó and   
Francisco Sánchez-Madrid and   
               Alicia G. Arroyo   ECM regulates MT1-MMP localization with
                                  $ \beta $1 or $ \alpha $v$ \beta $3
                                  integrins at distinct cell compartments
                                  modulating its internalization and
                                  activity on human endothelial cells  . . 509

Journal of Cell Biology
Volume 159, Number 4, November, 2002

                   Alan W. Dove   Suicide attempt linked to breakdown  . . ??
                   Alan W. Dove   CLIPs to the rescue  . . . . . . . . . . ??
                   Alan W. Dove   ER takes a faster track  . . . . . . . . ??
                   Alan W. Dove   Selecting synapse start sites  . . . . . ??
                   Alan W. Dove   A chaperone in motoneuron disease  . . . ??
              Nicole LeBrasseur   Viva the worm  . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Polyamino acids take amyloid form  . . . ??
              Nicole LeBrasseur   Poking a hole in mitochondria  . . . . . ??
              Nicole LeBrasseur   Putting a cap on reinitiation  . . . . . ??
              Nicole LeBrasseur   Dendritic cells can be self sustaining   ??
         Ruth A. Van Hatten and   
          Antonin V. Tutter and   
          Antonia H. Holway and   
        Alyssa M. Khederian and   
         Johannes C. Walter and   
             W. Matthew Michael   The \bionameXenopus Xmus101 protein is
                                  required for the recruitment of Cdc45 to
                                  origins of DNA replication . . . . . . . 541
         Jennifer G. DeLuca and   
                  Ben Moree and   
         Jennifer M. Hickey and   
          John V. Kilmartin and   
                   E. D. Salmon   hNuf2 inhibition blocks stable
                                  kinetochore--microtubule attachment and
                                  induces mitotic cell death in HeLa cells 549
            Yulia Ovechkina and   
          Michael Wagenbach and   
                 Linda Wordeman   K-loop insertion restores microtubule
                                  depolymerizing activity of a
                                  ``neckless'' MCAK mutant . . . . . . . . 557
          Heike Bömmel and   
                   Gang Xie and   
           Wilfried Rossoll and   
               Stefan Wiese and   
           Sibylle Jablonka and   
               Thomas Boehm and   
               Michael Sendtner   Missense mutation in the
                                  tubulin-specific chaperone E (Tbce) gene
                                  in the mouse mutant progressive motor
                                  neuronopathy, a model of human
                                  motoneuron disease . . . . . . . . . . . 563
       Torsten Wöllert and   
            Dieter G. Weiss and   
        Hans-Hermann Gerdes and   
            Sergei A. Kuznetsov   Activation of myosin V-based motility
                                  and F-actin-dependent network formation
                                  of endoplasmic reticulum during mitosis  571
             David Gatfield and   
               Elisa Izaurralde   REF1\slash Aly and the additional exon
                                  junction complex proteins are
                                  dispensable for nuclear mRNA export  . . 579
          Yulia A. Komarova and   
          Anna S. Akhmanova and   
         Shin-ichiro Kojima and   
              Niels Galjart and   
                 Gary G. Borisy   Cytoplasmic linker proteins promote
                                  microtubule rescue in vivo . . . . . . . 589
           Mahasin A. Osman and   
           James B. Konopka and   
             Richard A. Cerione   Iqg1p links spatial and secretion
                                  landmarks to polarity and cytokinesis    601
              Elena Rapizzi and   
               Paolo Pinton and   
      György Szabadkai and   
      Mariusz R. Wieckowski and   
Grégoire Vandecasteele and   
                Geoff Baird and   
            Richard A. Tuft and   
           Kevin E. Fogarty and   
                Rosario Rizzuto   Recombinant expression of the
                                  voltage-dependent anion channel enhances
                                  the transfer of Ca$^{2+}$ microdomains
                                  to mitochondria  . . . . . . . . . . . . 613
           Jyoti K. Jaiswal and   
           Norma W. Andrews and   
               Sanford M. Simon   Membrane proximal lysosomes are the
                                  major vesicles responsible for
                                  calcium-dependent exocytosis in
                                  nonsecretory cells . . . . . . . . . . . 625
               Raymond Chiu and   
             Leonid Novikov and   
           Shaeri Mukherjee and   
                 Dennis Shields   A caspase cleavage fragment of p115
                                  induces fragmentation of the Golgi
                                  apparatus and apoptosis  . . . . . . . . 637
            Vladimir Sytnyk and   
         Iryna Leshchyns'ka and   
             Markus Delling and   
           Galina Dityateva and   
         Alexander Dityatev and   
              Melitta Schachner   Neural cell adhesion molecule promotes
                                  accumulation of TGN organelles at sites
                                  of neuron-to-neuron contacts . . . . . . 649
         Matthew N. Rasband and   
             Eunice W. Park and   
               Dongkai Zhen and   
       Margaret I. Arbuckle and   
           Sebastian Poliak and   
                Elior Peles and   
           Seth G. N. Grant and   
               James S. Trimmer   Clustering of neuronal potassium
                                  channels is independent of their
                                  interaction with PSD-95  . . . . . . . . 663
            Asako Tsubouchi and   
             Junko Sakakura and   
                Ryohei Yagi and   
              Yuichi Mazaki and   
              Erik Schaefer and   
                Hajime Yano and   
                  Hisataka Sabe   Localized suppression of RhoA activity
                                  by Tyr31/$ 118$-phosphorylated paxillin
                                  in cell adhesion and migration . . . . . 673
             Fang-Ming Deng and   
             Feng-Xia Liang and   
                    Liyu Tu and   
         Katheryn A. Resing and   
                    Ping Hu and   
                Mark Supino and   
         Chih-Chi Andrew Hu and   
                    Ge Zhou and   
              Mingxiao Ding and   
              Gert Kreibich and   
                  Tung-Tien Sun   Uroplakin IIIb, a urothelial
                                  differentiation marker, dimerizes with
                                  uroplakin Ib as an early step of
                                  urothelial plaque assembly . . . . . . . 685
     Catherine G. Galbraith and   
          Kenneth M. Yamada and   
              Michael P. Sheetz   The relationship between force and focal
                                  complex development  . . . . . . . . . . 695

Journal of Cell Biology
Volume 159, Number 5, December, 2002

              Nicole LeBrasseur   Build actin at the right place, right
                                  time . . . . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Mads at the nuclear pore . . . . . . . . ??
              Nicole LeBrasseur   Nuclear travel costs energy  . . . . . . ??
              Nicole LeBrasseur   Sequences specify centromeric chromatin  ??
              Nicole LeBrasseur   Microtubules get early release . . . . . ??
               William A. Wells   When more is not more  . . . . . . . . . ??
               William A. Wells   Cells spin into view . . . . . . . . . . ??
               William A. Wells   Redox regulation . . . . . . . . . . . . ??
               William A. Wells   An exit strategy for the clean-up crew   ??
               William A. Wells   14-3-3, set me free  . . . . . . . . . . ??
                Miguel Abal and   
              Matthieu Piel and   
Veronique Bouckson-Castaing and   
             Mette Mogensen and   
     Jean-Baptiste Sibarita and   
                 Michel Bornens   Microtubule release from the centrosome
                                  in migrating cells . . . . . . . . . . . 731
             Stuart H. Read and   
          Belinda C. Baliga and   
              Paul G. Ekert and   
              David L. Vaux and   
                   Sharad Kumar   A novel Apaf-1--independent putative
                                  caspase-2 activation complex . . . . . . 739
             Claudio Rivera and   
                    Hong Li and   
     Judith Thomas-Crusells and   
           Hannele Lahtinen and   
              Tero Viitanen and   
      Avtandil Nanobashvili and   
                Zaal Kokaia and   
        Matti S. Airaksinen and   
                Juha Voipio and   
                  Kai Kaila and   
                    Mart Saarma   BDNF-induced TrkB activation
                                  down-regulates the K$^+$ -Cl$^{} - $
                                  cotransporter KCC2 and impairs neuronal
                                  Cl$^{} - $ extrusion . . . . . . . . . . 747
             Nicola L. Mahy and   
              Paul E. Perry and   
              Wendy A. Bickmore   Gene density and transcription influence
                                  the localization of chromatin outside of
                                  chromosome territories detectable by
                                  FISH . . . . . . . . . . . . . . . . . . 753
         Jun-ichirou Ohzeki and   
              Megumi Nakano and   
              Teruaki Okada and   
               Hiroshi Masumoto   CENP-B box is required for de novo
                                  centromere chromatin assembly on human
                                  alphoid DNA  . . . . . . . . . . . . . . 765
             Hiroshi Kimura and   
            Kimihiko Sugaya and   
                  Peter R. Cook   The transcription cycle of RNA
                                  polymerase II in living cells  . . . . . 777
           R. Ileng Kumaran and   
  Bhattiprolu Muralikrishna and   
               Veena K. Parnaik   Lamin A/C speckles mediate spatial
                                  organization of splicing factor
                                  compartments and RNA polymerase II
                                  transcription  . . . . . . . . . . . . . 783
          Alexandre Calapez and   
        Henrique M. Pereira and   
              Angelo Calado and   
          José Braga and   
           José Rino and   
      Célia Carvalho and   
  João Paulo Tavanez and   
                Elmar Wahle and   
          Agostinho C. Rosa and   
            Maria Carmo-Fonseca   The intranuclear mobility of messenger
                                  RNA binding proteins is ATP dependent
                                  and temperature sensitive  . . . . . . . 795
               Tatiana Iouk and   
            Oliver Kerscher and   
            Robert J. Scott and   
           Munira A. Basrai and   
             Richard W. Wozniak   The yeast nuclear pore complex
                                  functionally interacts with components
                                  of the spindle assembly checkpoint . . . 807
                 Sun H. Kim and   
                Seok J. Won and   
            Seonghyang Sohn and   
               Hyuk J. Kwon and   
                 Jee Y. Lee and   
               Jong H. Park and   
                 Byoung J. Gwag   Brain-derived neurotrophic factor can
                                  act as a pronecrotic factor through
                                  transcriptional and translational
                                  activation of NADPH oxidase  . . . . . . 821
           Matthew D. Smith and   
        Andreas Hiltbrunner and   
              Felix Kessler and   
               Danny J. Schnell   The targeting of the atToc159 preprotein
                                  receptor to the chloroplast outer
                                  membrane is mediated by its GTPase
                                  domain and is regulated by GTP . . . . . 833
            Jörg Bauer and   
        Andreas Hiltbrunner and   
               Petra Weibel and   
      Pierre-Alexandre Vidi and   
       Mayte Alvarez-Huerta and   
           Matthew D. Smith and   
           Danny J. Schnell and   
                  Felix Kessler   Essential role of the G-domain in
                                  targeting of the protein import receptor
                                  atToc159 to the chloroplast outer
                                  membrane . . . . . . . . . . . . . . . . 845
             Keiji Uchiyama and   
              Eija Jokitalo and   
                  Fumi Kano and   
            Masayuki Murata and   
             Xiaodong Zhang and   
               Benito Canas and   
             Richard Newman and   
        Catherine Rabouille and   
              Darryl Pappin and   
              Paul Freemont and   
                    Hisao Kondo   VCIP135, a novel essential factor for
                                  p97/p47-mediated membrane fusion, is
                                  required for Golgi and ER assembly in
                                  vivo . . . . . . . . . . . . . . . . . . 855
               Lisette Hari and   
    Véronique Brault and   
      Maurice Kléber and   
               Hye-Youn Lee and   
                Fabian Ille and   
           Rainer Leimeroth and   
         Christian Paratore and   
                 Ueli Suter and   
                Rolf Kemler and   
                   Lukas Sommer   Lineage-specific requirements of $ \beta
                                  $-catenin in neural crest development    867
             Kris A. DeMali and   
          Christy A. Barlow and   
                 Keith Burridge   Recruitment of the Arp2/3 complex to
                                  vinculin . . . . . . . . . . . . . . . . 881
         Katherine M. Smith and   
             Alban Gaultier and   
              Helene Cousin and   
        Dominique Alfandari and   
            Judith M. White and   
            Douglas W. DeSimone   The cysteine-rich domain regulates ADAM
                                  protease function in vivo  . . . . . . . 893

Journal of Cell Biology
Volume 159, Number 6, December, 2002

                   Alan W. Dove   Shining a light on growth cones  . . . . ??
                   Alan W. Dove   Making \bionameDictyostelium stick . . . ??
                   Alan W. Dove   Arp2\slash 3 gets inhibited  . . . . . . ??
                   Alan W. Dove   How to start a motor . . . . . . . . . . ??
                   Alan W. Dove   Using acid to find direction . . . . . . ??
              Nicole LeBrasseur   Vesicles slide on a synaptic body  . . . ??
              Nicole LeBrasseur   PilT . . . . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Neurons go toward the light  . . . . . . ??
              Nicole LeBrasseur   The brightest dots in the bunch  . . . . ??
              Nicole LeBrasseur   Vesicles that promise enlargement  . . . ??
                 Per Malkus and   
                 Feng Jiang and   
                 Randy Schekman   Concentrative sorting of secretory cargo
                                  proteins into COPII-coated vesicles  . . 915
             Damien Arnoult and   
            Philippe Parone and   
       Jean-Claude Martinou and   
            Bruno Antonsson and   
Jérôme Estaquier and   
            Jean Claude Ameisen   Mitochondrial release of
                                  apoptosis-inducing factor occurs
                                  downstream of cytochrome c release in
                                  response to several proapoptotic stimuli 923
          Mariusz Karbowski and   
                Yang-Ja Lee and   
             Brigitte Gaume and   
            Seon-Yong Jeong and   
              Stephan Frank and   
           Amotz Nechushtan and   
              Ansgar Santel and   
            Margaret Fuller and   
           Carolyn L. Smith and   
               Richard J. Youle   Spatial and temporal association of Bax
                                  with mitochondrial fission sites, Drp1,
                                  and Mfn2 during apoptosis  . . . . . . . 931
           Elaine C. Larsen and   
            Takehiko Ueyama and   
         Pamela M. Brannock and   
            Yasuhito Shirai and   
               Naoaki Saito and   
           Christer Larsson and   
           Daniel Loegering and   
             Peter B. Weber and   
           Michelle R. Lennartz   A role for PKC-$ \epsilon $ in Fc$
                                  \gamma $R-mediated phagocytosis by RAW
                                  264.7 cells  . . . . . . . . . . . . . . 939
           Sue L. Jaspersen and   
         Thomas H. Giddings and   
                     Mark Winey   Mps3p is a novel component of the yeast
                                  spindle pole body that interacts with
                                  the yeast centrin homologue Cdc31p . . . 945
François-Michel Boisvert and   
  Jocelyn Côté and   
Marie-Chloé Boulanger and   
     Patrick Cléroux and   
    François Bachand and   
           Chantal Autexier and   
        Stéphane Richard   Symmetrical dimethylarginine methylation
                                  is required for the localization of SMN
                                  in Cajal bodies and pre-mRNA splicing    957
              Claudia Kruse and   
           Andreas Jaedicke and   
        Joël Beaudouin and   
          Florian Böhl and   
              Dunja Ferring and   
        Thomas Güttler and   
              Jan Ellenberg and   
              Ralf-Peter Jansen   Ribonucleoprotein-dependent localization
                                  of the yeast class V myosin Myo4p  . . . 971
               Stan Burgess and   
                Matt Walker and   
                   Fei Wang and   
           James R. Sellers and   
            Howard D. White and   
            Peter J. Knight and   
                   John Trinick   The prepower stroke conformation of
                                  myosin V . . . . . . . . . . . . . . . . 983
     Christine L. Humphries and   
            Heath I. Balcer and   
      Jessica L. D'Agostino and   
             Barbara Winsor and   
            David G. Drubin and   
            Georjana Barnes and   
          Brenda J. Andrews and   
                 Bruce L. Goode   Direct regulation of Arp2/3 complex
                                  activity and function by the actin
                                  binding protein coronin  . . . . . . . . 993
             Arthur C. Huen and   
               Jung K. Park and   
             Lisa M. Godsel and   
                Xuejun Chen and   
           Leslie J. Bannon and   
       Evangeline V. Amargo and   
           Tracie Y. Hudson and   
             Anne K. Mongiu and   
             Irene M. Leigh and   
           David P. Kelsell and   
          Barry M. Gumbiner and   
              Kathleen J. Green   Intermediate filament--membrane
                                  attachments function synergistically
                                  with actin-dependent contacts to
                                  regulate intercellular adhesive strength 1005
          Sudhiranjan Gupta and   
          Nicole H. Purcell and   
                 Anning Lin and   
                      Subha Sen   Activation of nuclear factor-$ \kappa $B
                                  is necessary for myotrophin-induced
                                  cardiac hypertrophy  . . . . . . . . . . 1019
          Gianluca Baldanzi and   
       Nicoletta Filigheddu and   
            Santina Cutrupi and   
          Filomena Catapano and   
             Sara Bonissoni and   
             Alberto Fubini and   
              Daniela Malan and   
                Germano Baj and   
           Riccarda Granata and   
              Fabio Broglio and   
              Mauro Papotti and   
              Nicola Surico and   
         Federico Bussolino and   
             Jorgen Isgaard and   
           Romano Deghenghi and   
         Fabiola Sinigaglia and   
                 Maria Prat and   
         Giampiero Muccioli and   
                 Ezio Ghigo and   
                Andrea Graziani   Ghrelin and des-acyl ghrelin inhibit
                                  cell death in cardiomyocytes and
                                  endothelial cells through ERK1/2 and PI
                                  3-kinase/AKT . . . . . . . . . . . . . . 1029
           Vicki A. Sciorra and   
             Simon A. Rudge and   
                 Jiyao Wang and   
          Stuart McLaughlin and   
          JoAnne Engebrecht and   
               Andrew J. Morris   Dual role for phosphoinositides in
                                  regulation of yeast and mammalian
                                  phospholipase D enzymes  . . . . . . . . 1039
                   Paul Lee and   
                    Jie Rao and   
               Albert Fliss and   
                   Emy Yang and   
            Stephen Garrett and   
                Avrom J. Caplan   The Cdc37 protein kinase--binding domain
                                  is sufficient for protein kinase
                                  activity and cell viability  . . . . . . 1051
                   Zhong Ma and   
            Keena S. Thomas and   
              Donna J. Webb and   
              Radim Moravec and   
        Ana Maria Salicioni and   
              Wendy M. Mars and   
               Steven L. Gonias   Regulation of Rac1 activation by the low
                                  density lipoprotein receptor--related
                                  protein  . . . . . . . . . . . . . . . . 1061
           Erik H. J. Danen and   
            Petra Sonneveld and   
            Cord Brakebusch and   
      Reinhard Fässler and   
              Arnoud Sonnenberg   The fibronectin-binding integrins $
                                  \alpha $5$ \beta $1 and $ \alpha $v$
                                  \beta $3 differentially modulate
                                  RhoA--GTP loading, organization of cell
                                  matrix adhesions, and fibronectin
                                  fibrillogenesis  . . . . . . . . . . . . 1071
           Sheryl P. Denker and   
                Diane L. Barber   Cell migration requires both ion
                                  translocation and cytoskeletal anchoring
                                  by the Na--H exchanger NHE1  . . . . . . 1087
                 Yoko Nakai and   
             Hiroyuki Kamiguchi   Migration of nerve growth cones requires
                                  detergent-resistant membranes in a
                                  spatially defined and
                                  substrate-dependent manner . . . . . . . 1097
                  Petra Fey and   
           Stephen Stephens and   
          Margaret A. Titus and   
                Rex L. Chisholm   SadA, a novel adhesion receptor in
                                  \bionameDictyostelium  . . . . . . . . . 1109


Journal of Cell Biology
Volume 160, Number 1, January, 2003

              Nicole LeBrasseur   Caspases chew on electron transport  . . ??
              Nicole LeBrasseur   Rafts and the evil amyloids  . . . . . . ??
              Nicole LeBrasseur   The complex life of a GEF  . . . . . . . ??
              Nicole LeBrasseur   FRET-ing over scaffolds  . . . . . . . . ??
              Nicole LeBrasseur   RNA travels with ZBP1  . . . . . . . . . ??
               William A. Wells   The importance of catastrophe  . . . . . ??
               William A. Wells   Tubes go apical  . . . . . . . . . . . . ??
               William A. Wells   Cohesin resolves to let go . . . . . . . ??
               William A. Wells   Oscillating wildly . . . . . . . . . . . ??
               William A. Wells   A trigger for myelination  . . . . . . . ??
               Alpha S. Yap and   
                  Eva M. Kovacs   Direct cadherin-activated cell signaling 11
          Metello Innocenti and   
          Emanuela Frittoli and   
        Isabella Ponzanelli and   
              John R. Falck and   
        Saskia M. Brachmann and   
        Pier Paolo Di Fiore and   
                  Giorgio Scita   Phosphoinositide $3$-kinase activates
                                  Rac by entering in a complex with Eps8,
                                  Abi1, and Sos-1  . . . . . . . . . . . . 17
              Gohta Goshima and   
           Tomomi Kiyomitsu and   
                 Kinya Yoda and   
             Mitsuhiro Yanagida   Human centromere chromatin protein
                                  hMis12, essential for equal segregation,
                                  is independent of CENP--A loading
                                  pathway  . . . . . . . . . . . . . . . . 25
            Umrao R. Monani and   
         Matthew T. Pastore and   
       Tatiana O. Gavrilina and   
           Sibylle Jablonka and   
                Thanh T. Le and   
            Catia Andreassi and   
        Jennifer M. DiCocco and   
           Christian Lorson and   
         Elliot J. Androphy and   
           Michael Sendtner and   
             Michael Podell and   
           Arthur H. M. Burghes   A transgene carrying an A2G missense
                                  mutation in the SMN gene modulates
                                  phenotypic severity in mice with severe
                                  (type I) spinal muscular atrophy . . . . 41
            Thomas Kaufmann and   
              Sarah Schlipf and   
                Javier Sanz and   
              Karin Neubert and   
               Reuven Stein and   
               Christoph Borner   Characterization of the signal that
                                  directs Bcl-x$_L$, but not Bcl-2, to the
                                  mitochondrial outer membrane . . . . . . 53
         Jean-Ehrland Ricci and   
        Roberta A. Gottlieb and   
               Douglas R. Green   Caspase-mediated loss of mitochondrial
                                  function and generation of reactive
                                  oxygen species during apoptosis  . . . . 65
              Kim L. Farina and   
    Stefan Hüttelmaier and   
             Kiran Musunuru and   
             Robert Darnell and   
               Robert H. Singer   Two ZBP1 KH domains facilitate $ \beta
                                  $-actin mRNA localization, granule
                                  formation, and cytoskeletal attachment   77
              Carsten Brock and   
           Michael Schaefer and   
            H. Peter Reusch and   
          Cornelia Czupalla and   
           Manuela Michalke and   
            Karsten Spicher and   
        Günter Schultz and   
            Bernd Nürnberg   Roles of G$ \beta \gamma $ in membrane
                                  recruitment and activation of p110$
                                  \gamma $ /p101 phosphoinositide
                                  $3$-kinase $ \gamma $  . . . . . . . . . 89
           Seth F. Oliveria and   
              Lisa L. Gomez and   
             Mark L. Dell'Acqua   Imaging kinase--AKAP79--phosphatase
                                  scaffold complexes at the plasma
                                  membrane in living cells using FRET
                                  microscopy . . . . . . . . . . . . . . . 101
             Robert Ehehalt and   
             Patrick Keller and   
            Christian Haass and   
           Christoph Thiele and   
                     Kai Simons   Amyloidogenic processing of the
                                  Alzheimer $ \beta $-amyloid precursor
                                  protein depends on lipid rafts . . . . . 113
           Natsuko Tanimura and   
          Masakazu Nagafuku and   
              Yasuko Minaki and   
                Yukio Umeda and   
              Fumie Hayashi and   
             Junko Sakakura and   
                 Akiko Kato and   
       Douglas R. Liddicoat and   
               Masato Ogata and   
          Toshiyuki Hamaoka and   
                 Atsushi Kosugi   Dynamic changes in the mobility of LAT
                                  in aggregated lipid rafts upon T cell
                                  activation . . . . . . . . . . . . . . . 125
                    Li Zeng and   
                Xiaoning Si and   
                Wei-Ping Yu and   
                 Hoa Thi Le and   
               Kwok Peng Ng and   
         Raymond M. H. Teng and   
               Kenneth Ryan and   
          Dennis Z.-M. Wang and   
           Sathivel Ponniah and   
            Catherine J. Pallen   PTP$ \alpha $ regulates
                                  integrin-stimulated FAK
                                  autophosphorylation and cytoskeletal
                                  rearrangement in cell spreading and
                                  migration  . . . . . . . . . . . . . . . 137

Journal of Cell Biology
Volume 160, Number 2, January, 2003

                   Alan W. Dove   Tumor cells get primitive  . . . . . . . ??
                   Alan W. Dove   Venus dye trap catches executioners  . . ??
                   Alan W. Dove   Taking close-ups of a rafting trip . . . ??
                   Alan W. Dove   Rejection and killing, without MPR . . . ??
                   Alan W. Dove   An interaction that gets things started  ??
           Gillian M. Griffiths   Endocytosing the death sentence  . . . . 155
                  Lianwu Fu and   
                Elizabeth Sztul   Traffic-independent function of the
                                  Sar1p/COPII machinery in proteasomal
                                  sorting of the cystic fibrosis
                                  transmembrane conductance regulator  . . 157
               Ian A. Prior and   
            Cornelia Muncke and   
           Robert G. Parton and   
                John F. Hancock   Direct visualization of Ras proteins in
                                  spatially distinct cell surface
                                  microdomains . . . . . . . . . . . . . . 165
               Doris Martin and   
       Marianne Brown-Luedi and   
         Ruth Chiquet-Ehrismann   Tenascin-C signaling through induction
                                  of 14-3-3 tau  . . . . . . . . . . . . . 171
             Sandra Martins and   
              Sissel Eikvar and   
          Kazuhiro Furukawa and   
                Philippe Collas   HA95 and LAP2$ \beta $ mediate a novel
                                  chromatin--nuclear envelope interaction
                                  implicated in initiation of DNA
                                  replication  . . . . . . . . . . . . . . 177
              Hsiuchen Chen and   
            Scott A. Detmer and   
            Andrew J. Ewald and   
            Erik E. Griffin and   
            Scott E. Fraser and   
                  David C. Chan   Mitofusins Mfn1 and Mfn2 coordinately
                                  regulate mitochondrial fusion and are
                                  essential for embryonic development  . . 189
                  Aipo Diao and   
               Dinah Rahman and   
        Darryl J. C. Pappin and   
                John Lucocq and   
                    Martin Lowe   The coiled-coil membrane protein
                                  golgin-84 is a novel rab effector
                                  required for Golgi ribbon formation  . . 201
               Ian G. Mills and   
      Gerrit J. K. Praefcke and   
              Yvonne Vallis and   
             Brian J. Peter and   
             Lene E. Olesen and   
         Jennifer L. Gallop and   
      P. Jonathan G. Butler and   
            Philip R. Evans and   
              Harvey T. McMahon   EpsinR . . . . . . . . . . . . . . . . . 213
          Joseph A. Trapani and   
           Vivien R. Sutton and   
           Kevin Y. T. Thia and   
                  Yu Qin Li and   
    Christopher J. Froelich and   
              David A. Jans and   
           Mauro S. Sandrin and   
                Kylie A. Browne   A clathrin/dynamin- and
                                  mannose-$6$-phosphate
                                  receptor--independent pathway for
                                  granzyme B--induced cell death . . . . . 223
            Kiwamu Takemoto and   
             Takeharu Nagai and   
           Atsushi Miyawaki and   
                 Masayuki Miura   Spatio-temporal activation of caspase
                                  revealed by indicator that is
                                  insensitive to environmental effects . . 235
              Paola Bagnato and   
            Virigina Barone and   
        Emiliana Giacomello and   
              Daniela Rossi and   
            Vincenzo Sorrentino   Binding of an ankyrin-1 isoform to
                                  obscurin suggests a molecular link
                                  between the sarcoplasmic reticulum and
                                  myofibrils in striated muscles . . . . . 245
           Amy Shaub Maddox and   
                 Keith Burridge   RhoA is required for cortical retraction
                                  and rigidity during mitotic cell
                                  rounding . . . . . . . . . . . . . . . . 255
              Katarina Wolf and   
                 Irina Mazo and   
                Harry Leung and   
          Katharina Engelke and   
      Ulrich H. von Andrian and   
         Elena I. Deryugina and   
           Alex Y. Strongin and   
        Eva-B. Bröcker and   
                   Peter Friedl   Compensation mechanism in tumor cell
                                  migration  . . . . . . . . . . . . . . . 267

Journal of Cell Biology
Volume 160, Number 3, February, 2003

                   Alan W. Dove   Two motors, one transmission . . . . . . ??
                   Alan W. Dove   A model of missegregation  . . . . . . . ??
                   Alan W. Dove   Multimembrane fusion . . . . . . . . . . ??
                   Alan W. Dove   Urge to merge erects filopodia . . . . . ??
                   Alan W. Dove   Anthrax toxin takes charge . . . . . . . ??
               William A. Wells   Is Botryllus a natural killer? . . . . . ??
               William A. Wells   Bacterial aging  . . . . . . . . . . . . ??
               William A. Wells   Replicating dominos  . . . . . . . . . . ??
               William A. Wells   Hearts grow with the flow  . . . . . . . ??
               William A. Wells   Poised to migrate  . . . . . . . . . . . ??
                      Xin Xiang   LIS1 at the microtubule plus end and its
                                  role in dynein-mediated nuclear
                                  migration  . . . . . . . . . . . . . . . 289
                  Karen R. Dell   Dynactin polices two-way organelle
                                  traffic  . . . . . . . . . . . . . . . . 291
            Teymuras Kurzchalia   Anthrax toxin rafts into cells . . . . . 295
             Sean W. Deacon and   
        Anna S. Serpinskaya and   
        Patricia S. Vaughan and   
     Monica Lopez Fanarraga and   
            Isabelle Vernos and   
           Kevin T. Vaughan and   
            Vladimir I. Gelfand   Dynactin is required for bidirectional
                                  organelle transport  . . . . . . . . . . 297
              Edith D. Wong and   
         Jennifer A. Wagner and   
            Sidney V. Scott and   
            Voytek Okreglak and   
      Timothy J. Holewinske and   
          Ann Cassidy-Stone and   
                   Jodi Nunnari   The intramitochondrial dynamin-related
                                  GTPase, Mgm1p, is a component of a
                                  protein complex that mediates
                                  mitochondrial fusion . . . . . . . . . . 303
             Anne Pacquelet and   
                     Li Lin and   
          Pernille Ròrth   Binding site for p120/$ \delta $-catenin
                                  is not required for \bionameDrosophila
                                  E-cadherin function in vivo  . . . . . . 313
            Laurence Abrami and   
                 Shihui Liu and   
              Pierre Cosson and   
          Stephen H. Leppla and   
          F. Gisou van der Goot   Anthrax toxin triggers endocytosis of
                                  its receptor via a lipid raft--mediated
                                  clathrin-dependent process . . . . . . . 321
   Stéphanie Buvelot and   
          Sean Y. Tatsutani and   
           Danielle Vermaak and   
                    Sue Biggins   The budding yeast Ipl1/Aurora protein
                                  kinase regulates mitotic spindle
                                  disassembly  . . . . . . . . . . . . . . 329
             J. Ramesh Babu and   
      Karthik B. Jeganathan and   
            Darren J. Baker and   
               Xiaosheng Wu and   
       Ningling Kang-Decker and   
             Jan M. van Deursen   Rae1 is an essential mitotic checkpoint
                                  regulator that cooperates with Bub3 to
                                  prevent chromosome missegregation  . . . 341
                Wei-Lih Lee and   
          Jessica R. Oberle and   
                 John A. Cooper   The role of the lissencephaly protein
                                  Pac1 during nuclear migration in budding
                                  yeast  . . . . . . . . . . . . . . . . . 355
                    Li Wang and   
             Alexey J. Merz and   
           Kevin M. Collins and   
                William Wickner   Hierarchy of protein assembly at the
                                  vertex ring domain for yeast vacuole
                                  docking and fusion . . . . . . . . . . . 365
         Supriya Srinivasan and   
                   Fei Wang and   
              Suzana Glavas and   
              Alexander Ott and   
               Fred Hofmann and   
             Klaus Aktories and   
              Daniel Kalman and   
                Henry R. Bourne   Rac and Cdc42 play distinct roles in
                                  regulating PI(3,4,5)P$_3$ and polarity
                                  during neutrophil chemotaxis . . . . . . 375
          Sebastian Wiesner and   
           Emmanuele Helfer and   
            Dominique Didry and   
          Guylaine Ducouret and   
    Françoise Lafuma and   
       Marie-France Carlier and   
            Dominique Pantaloni   A biomimetic motility assay provides
                                  insight into the mechanism of
                                  actin-based motility . . . . . . . . . . 387
            Raymond S. Maul and   
                Yuhong Song and   
              Kurt J. Amann and   
            Sachi C. Gerbin and   
          Thomas D. Pollard and   
                 David D. Chang   EPLIN regulates actin dynamics by
                                  cross-linking and stabilizing filaments  399
        Tatyana M. Svitkina and   
          Elena A. Bulanova and   
              Oleg Y. Chaga and   
      Danijela M. Vignjevic and   
         Shin-ichiro Kojima and   
           Jury M. Vasiliev and   
                 Gary G. Borisy   Mechanism of filopodia initiation by
                                  reorganization of a dendritic network    409
             Maria S. Balda and   
        Michelle D. Garrett and   
                    Karl Matter   The ZO-1--associated Y-box factor ZONAB
                                  regulates epithelial cell proliferation
                                  and cell density . . . . . . . . . . . . 423
           Steven H. Myster and   
             Robert Cavallo and   
        Charles T. Anderson and   
              Donald T. Fox and   
                    Mark Peifer   Drosophila p120catenin plays a
                                  supporting role in cell adhesion but is
                                  not an essential adherens junction
                                  component  . . . . . . . . . . . . . . . 433

Journal of Cell Biology
Volume 160, Number 4, February, 2003

                   Alan W. Dove   Sticky cells in a prickly system . . . . ??
                   Alan W. Dove   TRAP builds a better translocon  . . . . ??
                   Alan W. Dove   This is your neuron on cannabinoids  . . ??
                   Alan W. Dove   Cajal compartments . . . . . . . . . . . ??
                   Alan W. Dove   Four channels, but only one program  . . ??
              Nicole LeBrasseur   Hox signals death for neuronal
                                  precursors . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Rec'd and repaired . . . . . . . . . . . ??
              Nicole LeBrasseur   Promoting passage in plasmodesmata . . . ??
              Nicole LeBrasseur   Keeping wing cells in line . . . . . . . ??
              Nicole LeBrasseur   A minus-end motor sees the plus side . . ??
           William A. Wells and   
              Nicole LeBrasseur   Stories of Cells . . . . . . . . . . . . 466
                    S. Papp and   
                   E. Dziak and   
                M. Michalak and   
                        M. Opas   Is all of the endoplasmic reticulum
                                  created equal? The effects of the
                                  heterogeneous distribution of
                                  endoplasmic reticulum Ca$^{2+}$-handling
                                  proteins . . . . . . . . . . . . . . . . 475
         Emma-Jane Williams and   
             Frank S. Walsh and   
                Patrick Doherty   The FGF receptor uses the
                                  endocannabinoid signaling system to
                                  couple to an axonal growth response  . . 481
        Savithri Rangarajan and   
         Jorrit M. Enserink and   
            H. Bea Kuiperij and   
             Johan de Rooij and   
               Leo S. Price and   
              Frank Schwede and   
                Johannes L. Bos   Cyclic AMP induces integrin-mediated
                                  cell adhesion through Epac and Rap1 upon
                                  stimulation of the $ \beta_2
                                  $-adrenergic receptor  . . . . . . . . . 487
        Korie E. Handwerger and   
           Christine Murphy and   
                 Joseph G. Gall   Steady-state dynamics of Cajal body
                                  components in the \bionameXenopus
                                  germinal vesicle . . . . . . . . . . . . 495
             David Stan\uek and   
           Stephen D. Rader and   
             Mirko Klingauf and   
            Karla M. Neugebauer   Targeting of U4/U6 small nuclear RNP
                                  assembly factor SART3/p110 to Cajal
                                  bodies . . . . . . . . . . . . . . . . . 505
          Scott C. Schuyler and   
               Jenny Y. Liu and   
                  David Pellman   The molecular function of Ase1p  . . . . 517
               Ryen D. Fons and   
         Brigitte A. Bogert and   
             Ramanujan S. Hegde   Substrate-specific function of the
                                  translocon-associated protein complex
                                  during translocation across the ER
                                  membrane . . . . . . . . . . . . . . . . 529
            Enrico Schleiff and   
           Jürgen Soll and   
       Michael Küchler and   
     Werner Kühlbrandt and   
                Roswitha Harrer   Characterization of the translocon of
                                  the outer envelope of chloroplasts . . . 541
      Marlies Messerschmitt and   
              Stefan Jakobs and   
                Frank Vogel and   
               Stefan Fritz and   
          Kai Stefan Dimmer and   
             Walter Neupert and   
            Benedikt Westermann   The inner membrane protein Mdm33
                                  controls mitochondrial morphology in
                                  yeast  . . . . . . . . . . . . . . . . . 553
                 Qiang Wang and   
                     Yi Xie and   
              Quan-Sheng Du and   
                Xiao-Jun Wu and   
                    Xu Feng and   
                    Lin Mei and   
            Jay M. McDonald and   
                Wen-Cheng Xiong   Regulation of the formation of
                                  osteoclastic actin rings by proline-rich
                                  tyrosine kinase 2 interacting with
                                  gelsolin . . . . . . . . . . . . . . . . 565
        Murray C. H. Clarke and   
                John Savill and   
             David B. Jones and   
           Brendon S. Noble and   
                 Simon B. Brown   Compartmentalized megakaryocyte death
                                  generates functional platelets committed
                                  to caspase-independent death . . . . . . 577
           Richard D. Evans and   
        Vivienne C. Perkins and   
             Alistair Henry and   
           Paul E. Stephens and   
         Martyn K. Robinson and   
                  Fiona M. Watt   A tumor-associated $ \beta $1 integrin
                                  mutation that abrogates epithelial
                                  differentiation control  . . . . . . . . 589
           Brian J. Hillier and   
             Victor D. Vacquier   Amassin, an olfactomedin protein,
                                  mediates the massive intercellular
                                  adhesion of sea urchin coelomocytes  . . 597
        Josephine M. Enciso and   
            Dita Gratzinger and   
          Todd D. Camenisch and   
              Sandra Canosa and   
               Emese Pinter and   
                Joseph A. Madri   Elevated glucose inhibits
                                  VEGF--A-mediated endocardial cushion
                                  formation  . . . . . . . . . . . . . . . 605

Journal of Cell Biology
Volume 160, Number 5, March, 2003

              Nicole LeBrasseur   The other side of kinetochore fibers . . ??
              Nicole LeBrasseur   Phosphorylation cycles on vesicles . . . ??
              Nicole LeBrasseur   PDE5 says NO to cGMP . . . . . . . . . . ??
              Nicole LeBrasseur   A protease inhibitor unsticks cells  . . ??
              Nicole LeBrasseur   Ran sticks a GEF to chromatin  . . . . . ??
               William A. Wells   Heterochromatingets dynamic  . . . . . . ??
               William A. Wells   Life on a bed of needles . . . . . . . . ??
               William A. Wells   Polarity feeds back  . . . . . . . . . . ??
               William A. Wells   Linking spindle to furrow  . . . . . . . ??
               William A. Wells   Exocytosis in action . . . . . . . . . . ??
          Rajesh Babu Sekar and   
               Ammasi Periasamy   Fluorescence resonance energy transfer
                                  (FRET) microscopy imaging of live cell
                                  protein localizations  . . . . . . . . . 629
               Hoi Yeung Li and   
                Denis Wirtz and   
                   Yixian Zheng   A mechanism of coupling RCC1 mobility to
                                  RanGTP production on the chromatin in
                                  vivo . . . . . . . . . . . . . . . . . . 635
             Olivier Cuvier and   
                 Tatsuya Hirano   A role of topoisomerase II in linking
                                  DNA replication to chromosome
                                  condensation . . . . . . . . . . . . . . 645
              Maureen Eijpe and   
            Hildo Offenberg and   
            Rolf Jessberger and   
        Ekaterina Revenkova and   
                Christa Heyting   Meiotic cohesin REC8 marks the axial
                                  elements of rat synaptonemal complexes
                                  before cohesins SMC1$ \beta $ and SMC3   657
           Alexey Khodjakov and   
             Lily Copenagle and   
          Michael B. Gordon and   
           Duane A. Compton and   
                Tarun M. Kapoor   Minus-end capture of preformed
                                  kinetochore fibers contributes to
                                  spindle morphogenesis  . . . . . . . . . 671
             Joachim Walter and   
         Lothar Schermelleh and   
              Marion Cremer and   
            Satoshi Tashiro and   
                  Thomas Cremer   Chromosome order in HeLa cells changes
                                  during mitosis and early G1, but is
                                  stably maintained during subsequent
                                  interphase stages  . . . . . . . . . . . 685
             Pradipta Ghosh and   
                Stuart Kornfeld   AP-1 binding to sorting signals and
                                  release from clathrin-coated vesicles is
                                  regulated by phosphorylation . . . . . . 699
          Tsuyoshi Miyazaki and   
                  Lynn Neff and   
               Sakae Tanaka and   
           William C. Horne and   
                   Roland Baron   Regulation of cytochrome c oxidase
                                  activity by c--Src in osteoclasts  . . . 709
      Florian Mullershausen and   
             Andreas Friebe and   
                Robert Feil and   
         W. Joseph Thompson and   
              Franz Hofmann and   
                 Doris Koesling   Direct activation of PDE5 by cGMP  . . . 719
    Gaëlle Benais-Pont and   
                   Anu Punn and   
  Catalina Flores-Maldonado and   
              Judith Eckert and   
        Graça Raposo and   
             Tom P. Fleming and   
        Marcelino Cereijido and   
             Maria S. Balda and   
                    Karl Matter   Identification of a tight
                                  junction--associated guanine nucleotide
                                  exchange factor that activates Rho and
                                  regulates paracellular permeability  . . 729
              R. Mark Grady and   
         Mohammed Akaaboune and   
         Alexander L. Cohen and   
        Margaret M. Maimone and   
           Jeff W. Lichtman and   
                Joshua R. Sanes   Tyrosine-phosphorylated and
                                  nonphosphorylated isoforms of $ \alpha
                                  $-dystrobrevin . . . . . . . . . . . . . 741
             Datsun A. Hsia and   
          Satyajit K. Mitra and   
          Christof R. Hauck and   
         Daniel N. Streblow and   
              Jay A. Nelson and   
                 Dusko Ilic and   
               Shuang Huang and   
                 Erguang Li and   
            Glen R. Nemerow and   
                   Jay Leng and   
      Kathryn S. R. Spencer and   
           David A. Cheresh and   
            David D. Schlaepfer   Differential regulation of cell motility
                                  and invasion by FAK  . . . . . . . . . . 753
                Osamu Inoue and   
        Katsue Suzuki-Inoue and   
            William L. Dean and   
               Jon Frampton and   
                Steve P. Watson   Integrin $ \alpha_2 \beta_1 $ mediates
                                  outside-in regulation of platelet
                                  spreading on collagen through activation
                                  of Src kinases and PLC$ \gamma $2  . . . 769
          Ralf-Peter Czekay and   
        Kathleen Aertgeerts and   
          Scott A. Curriden and   
             David J. Loskutoff   Plasminogen activator inhibitor-1
                                  detaches cells from extracellular
                                  matrices by inactivating integrins . . . 781

Journal of Cell Biology
Volume 160, Number 6, March, 2003

                   Alan W. Dove   When death starts with a caspase . . . . ??
                   Alan W. Dove   Fusion failure for flies . . . . . . . . ??
                   Alan W. Dove   When the channels leak, the muscle is
                                  weak . . . . . . . . . . . . . . . . . . ??
                   Alan W. Dove   Three AMIGOs grow a brain  . . . . . . . ??
                   Alan W. Dove   Stem cells to build muscles  . . . . . . ??
              Nicole LeBrasseur   Inducing Sprouty degradation . . . . . . ??
              Nicole LeBrasseur   Nucleoli come undone . . . . . . . . . . ??
              Nicole LeBrasseur   Nucleosomes get peeled and rewrapped . . ??
              Nicole LeBrasseur   Endosomes make tracks  . . . . . . . . . ??
              Nicole LeBrasseur   Riding Kar9 into the bud . . . . . . . . ??
              Darwin J. Prockop   Further proof of the plasticity of adult
                                  stem cells and their role in tissue
                                  repair . . . . . . . . . . . . . . . . . 807
              Anthony Bretscher   Polarized growth and organelle
                                  segregation in yeast . . . . . . . . . . 811
                  Anthony Brown   Axonal transport of membranous and
                                  nonmembranous cargoes  . . . . . . . . . 817
Hél\`ene Tourri\`ere and   
               Karim Chebli and   
               Latifa Zekri and   
           Brice Courselaud and   
       Jean Marie Blanchard and   
           Edouard Bertrand and   
                     Jamal Tazi   The RasGAP-associated endoribonuclease
                                  G3BP assembles stress granules . . . . . 823
       Karthikeyan Mythreye and   
                 Kerry S. Bloom   Differential kinetochore protein
                                  requirements for establishment versus
                                  propagation of centromere activity in
                                  \bionameSaccharomyces cerevisiae . . . . 833
         Meng-Fu Bryan Tsou and   
                     Wei Ku and   
               Adam Hayashi and   
                Lesilee S. Rose   PAR-dependent and geometry-dependent
                                  mechanisms of spindle positioning  . . . 845
              Elena Chiroli and   
          Roberta Fraschini and   
            Alessia Beretta and   
        Mariagrazia Tonelli and   
          Giovanna Lucchini and   
               Simonetta Piatti   Budding yeast PAK kinases regulate
                                  mitotic exit by two different mechanisms 857
            Sunil S. Metkar and   
                Baikun Wang and   
           Michelle L. Ebbs and   
                 Jin H. Kim and   
                Yong J. Lee and   
           Srikumar M. Raja and   
        Christopher J. Froelich   Granzyme B activates procaspase-3 which
                                  signals a mitochondrial amplification
                                  loop for maximal apoptosis . . . . . . . 875
            Kuniko Ishikawa and   
         Natalie L. Catlett and   
          Jennifer L. Novak and   
               Fusheng Tang and   
           Johnathan J. Nau and   
                Lois S. Weisman   Identification of an organelle-specific
                                  myosin V receptor  . . . . . . . . . . . 887
                Hongjun Liu and   
  Michelle Mardahl-Dumesnil and   
            Sean T. Sweeney and   
            Cahir J. O'Kane and   
           Sanford I. Bernstein   Drosophila paramyosin is important for
                                  myoblast fusion and essential for
                                  myofibril formation  . . . . . . . . . . 899
             Cosimo De Bari and   
       Francesco Dell'Accio and   
         Frank Vandenabeele and   
         Joris R. Vermeesch and   
       Jean-Marc Raymackers and   
                Frank P. Luyten   Skeletal muscle repair by adult human
                                  mesenchymal stem cells from synovial
                                  membrane . . . . . . . . . . . . . . . . 909
              Steven Reiken and   
           Alain Lacampagne and   
                   Hua Zhou and   
              Aftab Kherani and   
         Stephan E. Lehnart and   
                 Chris Ward and   
               Fannie Huang and   
          Marta Gaburjakova and   
           Jana Gaburjakova and   
             Nora Rosemblit and   
         Michelle S. Warren and   
                 Kun-lun He and   
                Geng-hua Yi and   
                   Jie Wang and   
            Daniel Burkhoff and   
                Guy Vassort and   
                Andrew R. Marks   PKA phosphorylation activates the
                                  calcium release channel (ryanodine
                                  receptor) in skeletal muscle . . . . . . 919
                    Bai Luo and   
        Stephen M. Prescott and   
              Matthew K. Topham   Association of diacylglycerol kinase $
                                  \zeta $ with protein kinase C $ \alpha $ 929
           Janice Robertson and   
      Mohammad M. Doroudchi and   
           Minh Dang Nguyen and   
          Heather D. Durham and   
          Michael J. Strong and   
                 Gerry Shaw and   
         Jean-Pierre Julien and   
            Walter E. Mushynski   A neurotoxic peripherin splice variant
                                  in a mouse model of ALS  . . . . . . . . 939
         Danijela Vignjevic and   
                Defne Yarar and   
           Matthew D. Welch and   
              John Peloquin and   
           Tatyana Svitkina and   
                 Gary G. Borisy   Formation of filopodia-like bundles in
                                  vitro from a dendritic network . . . . . 951
           Juha Kuja-Panula and   
   Marjaana Kiiltomäki and   
          Takashi Yamashiro and   
             Ari Rouhiainen and   
                 Heikki Rauvala   AMIGO, a transmembrane protein
                                  implicated in axon tract development,
                                  defines a novel protein family with
                                  leucine-rich repeats . . . . . . . . . . 963

Journal of Cell Biology
Volume 160, Number 7, March, 2003

              Nicole LeBrasseur   Building and breaking the NPC  . . . . . ??
              Nicole LeBrasseur   Calcium for strong clotting  . . . . . . ??
              Nicole LeBrasseur   Deacetylase undoes DNA damage  . . . . . ??
              Nicole LeBrasseur   DNA-free division  . . . . . . . . . . . ??
              Nicole LeBrasseur   Mitochondria sensitive to ER Ca$^{2+}$
                                  stores . . . . . . . . . . . . . . . . . ??
               William A. Wells   A boisterous histone . . . . . . . . . . ??
               William A. Wells   How old mothers can have young offspring ??
               William A. Wells   Hide and seek  . . . . . . . . . . . . . ??
               William A. Wells   Making stripes . . . . . . . . . . . . . ??
               William A. Wells   Chromosomes in the `hood . . . . . . . . ??
               William A. Wells   Movement in Colorado . . . . . . . . . . 985
        William C. Earnshaw and   
                    Mar Carmena   A perfect funeral with no corpse . . . . 989
          Emmanuel Lemichez and   
                 Patrice Boquet   To be helped or not helped, that is the
                                  question . . . . . . . . . . . . . . . . 991
     Elisabetta Bucciarelli and   
     Maria Grazia Giansanti and   
          Silvia Bonaccorsi and   
                 Maurizio Gatti   Spindle assembly and cytokinesis in the
                                  absence of chromosomes during
                                  \bionameDrosophila male meiosis  . . . . 993
            Tomohiko Fukuda and   
                   Lida Guo and   
                Xiaohua Shi and   
                    Chuanyue Wu   CH-ILKBP regulates cell survival by
                                  facilitating the membrane translocation
                                  of protein kinase B/Akt  . . . . . . . . 1001
          Lars H. Engelholm and   
                 Karin List and   
        Sarah Netzel-Arnett and   
             Edna Cukierman and   
            David J. Mitola and   
            Hannah Aaronson and   
        Lars Kjòller and   
    Jòrgen K. Larsen and   
          Kenneth M. Yamada and   
       Dudley K. Strickland and   
              Kenn Holmbeck and   
           Keld Danò and   
    Henning Birkedal-Hansen and   
             Niels Behrendt and   
                Thomas H. Bugge   uPARAP\slash Endo180 is essential for
                                  cellular uptake of collagen and promotes
                                  fibroblast collagen adhesion . . . . . . 1009
                Gary D. Kao and   
         W. Gillies McKenna and   
        Matthew G. Guenther and   
            Ruth J. Muschel and   
          Mitchell A. Lazar and   
                     Tim J. Yen   Histone deacetylase 4 interacts with
                                  53BP1 to mediate the DNA damage response 1017
          Frederic Kendirgi and   
            Dianne M. Barry and   
            Eric R. Griffis and   
          Maureen A. Powers and   
                 Susan R. Wente   An essential role for hGle1
                                  nucleocytoplasmic shuttling in mRNA
                                  export . . . . . . . . . . . . . . . . . 1029
            Kathryn J. Ryan and   
       J. Michael McCaffery and   
                 Susan R. Wente   The Ran GTPase cycle is required for
                                  yeast nuclear pore complex assembly  . . 1041
Péter Lénárt and   
  Gwénaël Rabut and   
            Nathalie Daigle and   
             Arthur R. Hand and   
              Mark Terasaki and   
                  Jan Ellenberg   Nuclear envelope breakdown in starfish
                                  oocytes proceeds by partial NPC
                                  disassembly followed by a rapidly
                                  spreading fenestration of nuclear
                                  membranes  . . . . . . . . . . . . . . . 1055
              Shyr-Jiann Li and   
              Mark Hochstrasser   The Ulp1 SUMO isopeptidase . . . . . . . 1069
                 Ana Berlin and   
              Anne Paoletti and   
                     Fred Chang   Mid2p stabilizes septin rings during
                                  cytokinesis in fission yeast . . . . . . 1083
            Joseph J. Tasto and   
        Jennifer L. Morrell and   
              Kathleen L. Gould   An anillin homologue, Mid2p, acts during
                                  fission yeast cytokinesis to organize
                                  the septin ring and promote cell
                                  separation . . . . . . . . . . . . . . . 1093
        Jean-Pierre Levraud and   
                Myriam Adam and   
Marie-Françoise Luciani and   
     Chantal de Chastellier and   
         Richard L. Blanton and   
                Pierre Golstein   \bionameDictyostelium cell death . . . . 1105
      David G. Breckenridge and   
          Marina Stojanovic and   
       Richard C. Marcellus and   
                Gordon C. Shore   Caspase cleavage product of BAP31
                                  induces mitochondrial fission through
                                  endoplasmic reticulum calcium signals,
                                  enhancing cytochrome c release to the
                                  cytosol  . . . . . . . . . . . . . . . . 1115
             N. D. Sonawane and   
                  A. S. Verkman   Determinants of [Cl$^{} - $] in
                                  recycling and late endosomes and Golgi
                                  complex measured using fluorescent
                                  ligands  . . . . . . . . . . . . . . . . 1129
                 Ryan Ratts and   
                Huiyan Zeng and   
               Eric A. Berg and   
                 Clare Blue and   
             Mark E. McComb and   
          Cathy E. Costello and   
      Johanna C. vanderSpek and   
                 John R. Murphy   The cytosolic entry of diphtheria toxin
                                  catalytic domain requires a host cell
                                  cytosolic translocation factor complex   1139
         Warwick S. Nesbitt and   
             Simon Giuliano and   
          Suhasini Kulkarni and   
          Sacha M. Dopheide and   
              Ian S. Harper and   
               Shaun P. Jackson   Intercellular calcium communication
                                  regulates platelet aggregation and
                                  thrombus growth  . . . . . . . . . . . . 1151


Journal of Cell Biology
Volume 161, Number 1, April, 2003

                    Eric C. Lai   RB pockets the cell cycle  . . . . . . . ??
                    Eric C. Lai   Life in a low calcium home . . . . . . . ??
                    Eric C. Lai   APP causes an energy crisis  . . . . . . ??
                    Eric C. Lai   Where new neurons come from  . . . . . . ??
                    Eric C. Lai   Lamas in loops . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Shaping up plants  . . . . . . . . . . . ??
              Nicole LeBrasseur   The spindle gets the Axs . . . . . . . . ??
              Nicole LeBrasseur   Ring around the chromatin  . . . . . . . ??
              Nicole LeBrasseur   Searching DNA in $3$D  . . . . . . . . . ??
             Nicole LeBrasseurr   Dying of a bad overhang  . . . . . . . . ??
               Patricia Camacho   Malaria parasites solve the problem of a
                                  low calcium environment  . . . . . . . . 17
          Aaron F. Severson and   
                 Bruce Bowerman   Myosin and the PAR proteins polarize
                                  microfilament-dependent forces that
                                  shape and position mitotic spindles in
                                  \bionameCaenorhabditis elegans . . . . . 21
           Antonino Colanzi and   
        Christine Sutterlin and   
                 Vivek Malhotra   RAF1-activated MEK1 is found on the
                                  Golgi apparatus in late prophase and is
                                  required for Golgi complex fragmentation
                                  in mitosis . . . . . . . . . . . . . . . 27
          Boyan K. Garvalov and   
         Theresa E. Higgins and   
        James D. Sutherland and   
               Markus Zettl and   
            Niki Scaplehorn and   
         Thomas Köcher and   
            Eugenia Piddini and   
           Gareth Griffiths and   
                    Michael Way   The conformational state of Tes
                                  regulates its zyxin-dependent
                                  recruitment to focal adhesions . . . . . 33
Hindupur K. Anandatheerthavarada and   
                Gopa Biswas and   
           Marie-Anne Robin and   
            Narayan G. Avadhani   Mitochondrial targeting and a novel
                                  transmembrane arrest of Alzheimer's
                                  amyloid precursor protein impairs
                                  mitochondrial function in neuronal cells 41
              Chun-Hong Xia and   
       Elizabeth A. Roberts and   
               Lu-Shiun Her and   
                 Xinran Liu and   
          David S. Williams and   
           Don W. Cleveland and   
       Lawrence S. B. Goldstein   Abnormal neurofilament transport caused
                                  by targeted disruption of neuronal
                                  kinesin heavy chain KIF5A  . . . . . . . 55
           Olivier D. Lohez and   
           Caroline Reynaud and   
               Franck Borel and   
         Paul R. Andreassen and   
             Robert L. Margolis   Arrest of mammalian fibroblasts in G1 in
                                  response to actin inhibition is
                                  dependent on retinoblastoma pocket
                                  proteins but not on p53  . . . . . . . . 67
              Kiyoko Fukami and   
             Manabu Yoshida and   
             Takafumi Inoue and   
            Manabu Kurokawa and   
          Rafael A. Fissore and   
            Nobuaki Yoshida and   
        Katsuhiko Mikoshiba and   
               Tadaomi Takenawa   Phospholipase C$ \delta $4 is required
                                  for Ca$^{2+}$ mobilization essential for
                                  acrosome reaction in sperm . . . . . . . 79
              Chris D. Wood and   
            Alberto Darszon and   
               Michael Whitaker   Speract induces calcium oscillations in
                                  the sperm tail . . . . . . . . . . . . . 89
         Marcos L. Gazarini and   
           Andrew P. Thomas and   
              Tullio Pozzan and   
      Célia R. S. Garcia   Calcium signaling in a low calcium
                                  environment  . . . . . . . . . . . . . . 103
            Valerie Horsley and   
               Grace K. Pavlath   Prostaglandin F$_{2 \alpha }$ stimulates
                                  growth of skeletal muscle cells via an
                                  NFATC2-dependent pathway . . . . . . . . 111
              Anna Popsueva and   
           Dmitry Poteryaev and   
               Elena Arighi and   
              Xiaojuan Meng and   
   Alexandre Angers-Loustau and   
               David Kaplan and   
                Mart Saarma and   
                  Hannu Sariola   GDNF promotes tubulogenesis of GFR$
                                  \alpha $1-expressing MDCK cells by
                                  Src-mediated phosphorylation of Met
                                  receptor tyrosine kinase . . . . . . . . 119
                Huaye Zhang and   
              Donna J. Webb and   
         Hannelore Asmussen and   
                Alan F. Horwitz   Synapse formation is regulated by the
                                  signaling adaptor GIT1 . . . . . . . . . 131
      Götz von Wichert and   
              Guoying Jiang and   
                 Ana Kostic and   
                Kurt De Vos and   
                    Jan Sap and   
              Michael P. Sheetz   RPTP-$ \alpha $ acts as a transducer of
                                  mechanical force on $ \alpha_v \slash
                                  \beta_3 $-integrin-cytoskeleton linkages 143
      Zohreh Mostafavi-Pour and   
            Janet A. Askari and   
         Scott J. Parkinson and   
            Peter J. Parker and   
              Tony T. C. Ng and   
            Martin J. Humphries   Integrin-specific signaling pathways
                                  controlling focal adhesion formation and
                                  cell migration . . . . . . . . . . . . . 155
         Shibeshih Belachew and   
         Ramesh Chittajallu and   
            Adan A. Aguirre and   
              Xiaoqing Yuan and   
               Martha Kirby and   
            Stacie Anderson and   
                 Vittorio Gallo   Postnatal NG2 proteoglycan--expressing
                                  progenitor cells are intrinsically
                                  multipotent and generate functional
                                  neurons  . . . . . . . . . . . . . . . . 169
             Yamato Kikkawa and   
              Ismo Virtanen and   
               Jeffrey H. Miner   Mesangial cells organize the glomerular
                                  capillaries by adhering to the G domain
                                  of laminin $ \alpha $5 in the glomerular
                                  basement membrane  . . . . . . . . . . . 187
              Susann Schenk and   
           Edith Hintermann and   
              Martin Bilban and   
          Naohiko Koshikawa and   
              Carlo Hojilla and   
                Rama Khokha and   
                  Vito Quaranta   Binding to EGF receptor of a laminin-5
                                  EGF-like fragment liberated during
                                  MMP-dependent mammary gland involution   197

Journal of Cell Biology
Volume 161, Number 2, April, 2003

              Nicole LeBrasseur   Aurora B puts chromosomes in their place ??
              Nicole LeBrasseur   To grow or to shrink \ldots  . . . . . . ??
              Nicole LeBrasseur   H. pylori mobilizes cells  . . . . . . . ??
              Nicole LeBrasseur   Choosing replication origins . . . . . . ??
              Nicole LeBrasseur   Say NO to insulin  . . . . . . . . . . . ??
                 Rabiya S. Tuma   ROS for your roots . . . . . . . . . . . ??
                 Rabiya S. Tuma   Conserving synaptic weight . . . . . . . ??
                 Rabiya S. Tuma   Reconstituting a chloroplast transport
                                  system . . . . . . . . . . . . . . . . . ??
                 Rabiya S. Tuma   Calcium waves in membrane fusion . . . . ??
                 Rabiya S. Tuma   Toxoplasma uses tough love . . . . . . . ??
           Andrea D. Weston and   
             Bruce Blumberg and   
           T. Michael Underhill   Active repression by unliganded retinoid
                                  receptors in development . . . . . . . . 223
               Alper Romano and   
                Annika Guse and   
         Ivica Krascenicova and   
            Heinke Schnabel and   
              Ralf Schnabel and   
                Michael Glotzer   Csc-1  . . . . . . . . . . . . . . . . . 229
          Danny Köhler and   
             Christine Ruff and   
        Edgar Meyhöfer and   
             Martin Bähler   Different degrees of lever arm rotation
                                  control myosin step size . . . . . . . . 237
              Mark A. Rizzo and   
                David W. Piston   Regulation of $ \beta $ cell glucokinase
                                  by S-nitrosylation and association with
                                  nitric oxide synthase  . . . . . . . . . 243
                Yuri Churin and   
             Laila Al-Ghoul and   
                Oliver Kepp and   
            Thomas F. Meyer and   
          Walter Birchmeier and   
                Michael Naumann   Helicobacter pylori CagA protein targets
                                  the c--Met receptor and enhances the
                                  motogenic response . . . . . . . . . . . 249
                    Feng Li and   
               Jianhua Chen and   
           Eduardo Solessio and   
               David M. Gilbert   Spatial distribution and specification
                                  of mammalian replication origins during
                                  G1 phase . . . . . . . . . . . . . . . . 257
          Claire Ditchfield and   
        Victoria L. Johnson and   
              Anthony Tighe and   
            Rebecca Ellston and   
            Carolyn Haworth and   
             Trevor Johnson and   
            Andrew Mortlock and   
              Nicholas Keen and   
              Stephen S. Taylor   Aurora B couples chromosome alignment
                                  with anaphase by targeting BubR1, Mad2,
                                  and Cenp--E to kinetochores  . . . . . . 267
                 Silke Hauf and   
            Richard W. Cole and   
            Sabrina LaTerra and   
           Christine Zimmer and   
             Gisela Schnapp and   
              Rainer Walter and   
               Armin Heckel and   
           Jacques van Meel and   
            Conly L. Rieder and   
             Jan-Michael Peters   The small molecule Hesperadin reveals a
                                  role for Aurora B in correcting
                                  kinetochore--microtubule attachment and
                                  in maintaining the spindle assembly
                                  checkpoint . . . . . . . . . . . . . . . 281
           Alison L. Pidoux and   
         William Richardson and   
              Robin C. Allshire   Sim4 . . . . . . . . . . . . . . . . . . 295
              Michael Doyle and   
             Michael F. Jantsch   Distinct in vivo roles for
                                  double-stranded RNA-binding domains of
                                  the \bionameXenopus RNA-editing enzyme
                                  ADAR1 in chromosomal targeting . . . . . 309
      Franco J. Vizeacoumar and   
      Juan C. Torres-Guzman and   
             Yuen Yi C. Tam and   
          John D. Aitchison and   
         Richard A. Rachubinski   YHR150w and YDR479c encode peroxisomal
                                  integral membrane proteins involved in
                                  the regulation of peroxisome number,
                                  size, and distribution in
                                  \bionameSaccharomyces cerevisiae . . . . 321
             Esther J. Chen and   
                Chris A. Kaiser   LST8 negatively regulates amino acid
                                  biosynthesis as a component of the TOR
                                  pathway  . . . . . . . . . . . . . . . . 333
          Mimi Shirasu-Hiza and   
               Peg Coughlin and   
                  Tim Mitchison   Identification of XMAP215 as a
                                  microtubule-destabilizing factor in
                                  \bionameXenopus egg extract by
                                  biochemical purification . . . . . . . . 349
           Mark van Breugel and   
             David Drechsel and   
                  Anthony Hyman   Stu2p, the budding yeast member of the
                                  conserved Dis1/XMAP215 family of
                                  microtubule-associated proteins is a
                                  plus end--binding microtubule
                                  destabilizer . . . . . . . . . . . . . . 359
          Robert S. Fischer and   
      Kimberly L. Fritz-Six and   
                Velia M. Fowler   Pointed-end capping by tropomodulin3
                                  negatively regulates endothelial cell
                                  motility . . . . . . . . . . . . . . . . 371
            Yoshiki Arakawa and   
              Haruhiko Bito and   
       Tomoyuki Furuyashiki and   
             Takahiro Tsuji and   
     Sayaka Takemoto-Kimura and   
            Kazuhiro Kimura and   
            Kazuhiko Nozaki and   
            Nobuo Hashimoto and   
                  Shuh Narumiya   Control of axon elongation via an SDF-1$
                                  \alpha $ /Rho/mDia pathway in cultured
                                  cerebellar granule neurons . . . . . . . 381
            David M. McKean and   
              Lila Sisbarro and   
                 Dusko Ilic and   
  Nihal Kaplan-Alburquerque and   
           Raphael Nemenoff and   
          Mary Weiser-Evans and   
            Michael J. Kern and   
              Peter Lloyd Jones   FAK induces expression of Prx1 to
                                  promote tenascin--C-dependent fibroblast
                                  migration  . . . . . . . . . . . . . . . 393
        Stefan Bonné and   
            Barbara Gilbert and   
         Mechthild Hatzfeld and   
                 Xinyu Chen and   
          Kathleen J. Green and   
                  Frans van Roy   Defining desmosomal plakophilin-3
                                  interactions . . . . . . . . . . . . . . 403
             Mika Shimonaka and   
              Koko Katagiri and   
         Toshinori Nakayama and   
               Naoya Fujita and   
             Takashi Tsuruo and   
               Osamu Yoshie and   
                 Tatsuo Kinashi   Rap1 translates chemokine signals to
                                  integrin activation, cell polarization,
                                  and motility across vascular endothelium
                                  under flow . . . . . . . . . . . . . . . 417
     Beata Wojciak-Stothard and   
                 Anne J. Ridley   Shear stress--induced endothelial cell
                                  polarization is mediated by Rho and Rac
                                  but not Cdc42 or PI $3$-kinases  . . . . 429

Journal of Cell Biology
Volume 161, Number 3, May, 2003

                   Alan W. Dove   Stressed cells dance on a bright stage   ??
                   Alan W. Dove   Cut protein to boost fibers  . . . . . . ??
                   Alan W. Dove   Breaking down barriers . . . . . . . . . ??
                   Alan W. Dove   Getting a handle on centrosomes  . . . . ??
                   Alan W. Dove   The neutrophil as firefighter  . . . . . ??
                 Rabiya S. Tuma   MicroRNAs make big splash in apoptosis   ??
                 Rabiya S. Tuma   Shared amyloid oligomer structure proves
                                  toxic  . . . . . . . . . . . . . . . . . ??
                 Rabiya S. Tuma   Math connects vascular network to the
                                  universe . . . . . . . . . . . . . . . . ??
                 Rabiya S. Tuma   Turning RacGAP into a RhoGAP . . . . . . ??
                 Rabiya S. Tuma   Crm1 locks up replication factors  . . . ??
                Karl Matter and   
                 Maria S. Balda   Holey barrier  . . . . . . . . . . . . . 459
           Jeffery W. Kelly and   
               William E. Balch   Amyloid as a natural product . . . . . . 461
                Ira Mellman and   
                    Tom Misteli   Computational cell biology . . . . . . . 463
          John D. Aitchison and   
               Timothy Galitski   Inventories to insights  . . . . . . . . 465
    José M. G. Vilar and   
            C\ualin C. Guet and   
              Stanislas Leibler   Modeling network dynamics  . . . . . . . 471
                Roland Eils and   
               Chaitanya Athale   Computational imaging in cell biology    477
                 Eric Hwang and   
              Justine Kusch and   
                Yves Barral and   
                Tim C. Huffaker   Spindle orientation in
                                  \bionameSaccharomyces cerevisiae depends
                                  on the transport of microtubule ends
                                  along polarized actin cables . . . . . . 483
            Steven Ackerley and   
             Paul Thornhill and   
         Andrew J. Grierson and   
            Janet Brownlees and   
          Brian H. Anderton and   
             P. Nigel Leigh and   
        Christopher E. Shaw and   
       Christopher C. J. Miller   Neurofilament heavy chain side arm
                                  phosphorylation regulates axonal
                                  transport of neurofilaments  . . . . . . 489
             Michel Jacquet and   
            Georges Renault and   
              Sylvie Lallet and   
                 Jan De Mey and   
               Albert Goldbeter   Oscillatory nucleocytoplasmic shuttling
                                  of the general stress response
                                  transcriptional activators Msn2 and Msn4
                                  in \bionameSaccharomyces cerevisiae  . . 497
                Gopa Biswas and   
Hindupur K. Anandatheerthavarada and   
                 Mone Zaidi and   
            Narayan G. Avadhani   Mitochondria to nucleus stress signaling 507
           Joanne F. Berson and   
         Alexander C. Theos and   
             Dawn C. Harper and   
             Danielle Tenza and   
        Graça Raposo and   
               Michael S. Marks   Proprotein convertase cleavage liberates
                                  a fibrillogenic fragment of a resident
                                  glycoprotein to initiate melanosome
                                  biogenesis . . . . . . . . . . . . . . . 521
               Adam Gromley and   
              Agata Jurczyk and   
          James Sillibourne and   
            Ensar Halilovic and   
             Mette Mogensen and   
             Irina Groisman and   
           Maureen Blomberg and   
                 Stephen Doxsey   A novel human protein of the maternal
                                  centriole is required for the final
                                  stages of cytokinesis and entry into S
                                  phase  . . . . . . . . . . . . . . . . . 535
         Gabriella Castoria and   
             Maria Lombardi and   
      Maria Vittoria Barone and   
           Antonio Bilancio and   
         Marina Di Domenico and   
            Daniela Bottero and   
              Flavia Vitale and   
          Antimo Migliaccio and   
           Ferdinando Auricchio   Androgen-stimulated DNA synthesis and
                                  cytoskeletal changes in fibroblasts by a
                                  nontranscriptional receptor action . . . 547
           Kurt L. Barkalow and   
         Joseph E. Italiano and   
             Denise E. Chou and   
          Yoichiro Matsuoka and   
               Vann Bennett and   
                John H. Hartwig   $ \alpha $-Adducin dissociates from
                                  F-actin and spectrin during platelet
                                  activation . . . . . . . . . . . . . . . 557
              Sophie Nicole and   
        Benedicte Desforges and   
              Gaelle Millet and   
           Jeanne Lesbordes and   
      Carmen Cifuentes-Diaz and   
                Dora Vertes and   
                My Linh Cao and   
         Fabienne De Backer and   
         Laetitia Languille and   
             Natacha Roblot and   
              Vandana Joshi and   
          Jean-Marie Gillis and   
                   Judith Melki   Intact satellite cells lead to
                                  remarkable protection against Smn gene
                                  defect in differentiated skeletal muscle 571
                Rui-An Wang and   
         Ratna K. Vadlamudi and   
     Rozita Bagheri-Yarmand and   
               Iwan Beuvink and   
             Nancy E. Hynes and   
                   Rakesh Kumar   Essential functions of p21-activated
                                  kinase 1 in morphogenesis and
                                  differentiation of mammary glands  . . . 583
                  V. Sriram and   
             K. S. Krishnan and   
                 Satyajit Mayor   deep-orange and carnation define
                                  distinct stages in late endosomal
                                  biogenesis in \bionameDrosophila
                                  melanogaster . . . . . . . . . . . . . . 593
        Tanja Wucherpfennig and   
Michaela Wilsch-Bräuninger and   
Marcos González-Gaitán   Role of \bionameDrosophila Rab5 during
                                  endosomal trafficking at the synapse and
                                  evoked neurotransmitter release  . . . . 609
         Iryna Leshchyns'ka and   
            Vladimir Sytnyk and   
              Jon S. Morrow and   
              Melitta Schachner   Neural cell adhesion molecule (NCAM)
                                  association with PKC$ \beta_2 $ via $
                                  \beta $I spectrin is implicated in
                                  NCAM-mediated neurite outgrowth  . . . . 625
        Gediminas Cepinskas and   
          Jurate Savickiene and   
          Carmen V. Ionescu and   
               Peter R. Kvietys   PMN transendothelial migration decreases
                                  nuclear NF$ \kappa $B in IL-1$ \beta
                                  $-activated endothelial cells  . . . . . 641
             Takehiro Nitta and   
                Masaki Hata and   
              Shimpei Gotoh and   
              Yoshiteru Seo and   
            Hiroyuki Sasaki and   
            Nobuo Hashimoto and   
               Mikio Furuse and   
              Shoichiro Tsukita   Size-selective loosening of the
                                  blood-brain barrier in
                                  claudin-$5$--deficient mice  . . . . . . 653

Journal of Cell Biology
Volume 161, Number 4, May, 2003

                   Alan W. Dove   Tumor cells  . . . . . . . . . . . . . . ??
                   Alan W. Dove   Modulating AMPA receptors makes memories
                                  special  . . . . . . . . . . . . . . . . ??
                   Alan W. Dove   Dance of the podosomes . . . . . . . . . ??
                   Alan W. Dove   Glycosylation's active site --- finally  ??
                   Alan W. Dove   Coping with the stress of morphogenesis  ??
               William A. Wells   Small minerals make strong bones . . . . ??
               William A. Wells   Selectins with a catch . . . . . . . . . ??
               William A. Wells   Calcium goes nuclear . . . . . . . . . . ??
               William A. Wells   Metastasizing in search of oxygen  . . . ??
               William A. Wells   A graveyard for mRNA . . . . . . . . . . ??
                 Rebecca Kellum   Is HP1 an RNA detector that functions
                                  both in repression and activation? . . . 671
               Ivan R. Nabi and   
                   Phuong U. Le   Caveolae\slash raft-dependent
                                  endocytosis  . . . . . . . . . . . . . . 673
           Ronald S. Ullers and   
         Edith N. G. Houben and   
               Amanda Raine and   
Corinne M. ten Hagen-Jongman and   
       Måns Ehrenberg and   
             Joseph Brunner and   
               Bauke Oudega and   
               Nellie Harms and   
                   Joen Luirink   Interplay of signal recognition particle
                                  and trigger factor at L23 near the
                                  nascent chain exit site on the
                                  \bionameEscherichia coli ribosome  . . . 679
                     Yue Hu and   
                Mark E. Fortini   Different cofactor activities in $
                                  \gamma $-secretase assembly  . . . . . . 685
              Nia J. Bryant and   
                 David E. James   The Sec1p/Munc18 (SM) protein, Vps45p,
                                  cycles on and off membranes during
                                  vesicle transport  . . . . . . . . . . . 691
             James G. Evans and   
               Ivan Correia and   
             Olga Krasavina and   
               Nicki Watson and   
                Paul Matsudaira   Macrophage podosomes assemble at the
                                  leading lamella by growth and
                                  fragmentation  . . . . . . . . . . . . . 697
           Lucia Piacentini and   
                Laura Fanti and   
              Maria Berloco and   
            Barbara Perrini and   
              Sergio Pimpinelli   Heterochromatin protein 1 (HP1) is
                                  associated with induced gene expression
                                  in \bionameDrosophila euchromatin  . . . 707
           IngMarie Nilsson and   
         Daniel J. Kelleher and   
                 Yiwei Miao and   
              Yuanlong Shao and   
              Gert Kreibich and   
               Reid Gilmore and   
          Gunnar von Heijne and   
              Arthur E. Johnson   Photocross-linking of nascent chains to
                                  the STT3 subunit of the
                                  oligosaccharyltransferase complex  . . . 715
             Eric Lacazette and   
           Sophie Le Calvez and   
          Nadesan Gajendran and   
            Hans Rudolf Brenner   A novel pathway for MuSK to induce key
                                  genes in neuromuscular synapse formation 727
                  Ona Bloom and   
              Emma Evergren and   
            Nikolay Tomilin and   
              Ole Kjaerulff and   
             Peter Löw and   
             Lennart Brodin and   
       Vincent A. Pieribone and   
             Paul Greengard and   
                Oleg Shupliakov   Colocalization of synapsin and actin
                                  during synaptic vesicle recycling  . . . 737
            Daniel Jaquemar and   
          Sergey Kupriyanov and   
             Miriam Wankell and   
            Jacqueline Avis and   
            Kurt Benirschke and   
  Hél\`ene Baribault and   
               Robert G. Oshima   Keratin 8 protection of placental
                                  barrier function . . . . . . . . . . . . 749
            Julia M. Bosher and   
               Bum-Soo Hahn and   
             Renaud Legouis and   
           Satis Sookhareea and   
            Robby M. Weimer and   
            Anne Gansmuller and   
         Andrew D. Chisholm and   
                Ann M. Rose and   
       Jean-Louis Bessereau and   
               Michel Labouesse   The \bionameCaenorhabditis elegans
                                  vab-10 spectraplakin isoforms protect
                                  the epidermis against internal and
                                  external forces  . . . . . . . . . . . . 757
          Laird C. Sheldahl and   
         Diane C. Slusarski and   
               Petra Pandur and   
          Jeffrey R. Miller and   
          Michael Kühl and   
                Randall T. Moon   Dishevelled activates Ca$^{2+}$ flux,
                                  PKC, and CamKII in vertebrate embryos    769
                   Chang Xu and   
               James Watras and   
                 Leslie M. Loew   Kinetic analysis of receptor-activated
                                  phosphoinositide turnover  . . . . . . . 779
    Maria Grazia Lampugnani and   
            Adriana Zanetti and   
              Monica Corada and   
         Takamune Takahashi and   
           Giovanna Balconi and   
        Ferruccio Breviario and   
          Fabrizio Orsenigo and   
             Anna Cattelino and   
                Rolf Kemler and   
           Thomas O. Daniel and   
              Elisabetta Dejana   Contact inhibition of VEGF-induced
                                  proliferation requires vascular
                                  endothelial cadherin, $ \beta $-catenin,
                                  and the phosphatase DEP-1/CD148  . . . . 793
              Susumu Tomita and   
                    Lu Chen and   
           Yoshimi Kawasaki and   
         Ronald S. Petralia and   
         Robert J. Wenthold and   
            Roger A. Nicoll and   
                 David S. Bredt   Functional studies and distribution
                                  define a family of transmembrane AMPA
                                  receptor regulatory proteins . . . . . . 805
               Thomas Manes and   
               Duo-Qi Zheng and   
              Simona Tognin and   
             Amy S. Woodard and   
       Pier Carlo Marchisio and   
              Lucia R. Languino   $ \alpha_v \beta_3 $ integrin expression
                                  up-regulates cdc2, which modulates cell
                                  migration  . . . . . . . . . . . . . . . 817

Journal of Cell Biology
Volume 161, Number 5, June, 2003

                   Alan W. Dove   Conjunctions of junctions  . . . . . . . ??
                   Alan W. Dove   Wrong connexin signals cataracts . . . . ??
                   Alan W. Dove   Agrin at CNS synapses  . . . . . . . . . ??
                   Alan W. Dove   Catching a kinase in the act . . . . . . ??
                   Alan W. Dove   Fusion promoter or fusion inhibitor? . . ??
              Nicole LeBrasseur   A view of antibody maturation  . . . . . ??
              Nicole LeBrasseur   GPR-1\slash 2 support unequal division   ??
              Nicole LeBrasseur   Apoptosis leaves its mark on chromatin   ??
              Nicole LeBrasseur   A cytokine that packs a punch  . . . . . ??
              Nicole LeBrasseur   Cyclin B knows its place . . . . . . . . ??
                   Mike Rossner   The JCB 2003 . . . . . . . . . . . . . . 837
               Joanna Cichy and   
              Ellen Puré   The liberation of CD44 . . . . . . . . . 839
           Torsten Wittmann and   
             Gary M. Bokoch and   
       Clare M. Waterman-Storer   Regulation of leading edge microtubule
                                  and actin dynamics downstream of Rac1    845
           Olga Krylyshkina and   
           Kurt I. Anderson and   
             Irina Kaverina and   
               Irene Upmann and   
        Dietmar J. Manstein and   
            J. Victor Small and   
                Derek K. Toomre   Nanometer targeting of microtubules to
                                  focal adhesions  . . . . . . . . . . . . 853
           William Schubert and   
             Xiao Yong Yang and   
           Teddy T. C. Yang and   
          Stephen M. Factor and   
         Michael P. Lisanti and   
       Jeffery D. Molkentin and   
     Mercedes Rincón and   
                  Chi-Wing Chow   Requirement of transcription factor NFAT
                                  in developing atrial myocardium  . . . . 861
             David R. Kovar and   
            Jeffrey R. Kuhn and   
            Andrea L. Tichy and   
              Thomas D. Pollard   The fission yeast cytokinesis formin
                                  Cdc12p is a barbed end actin filament
                                  capping protein gated by profilin  . . . 875
            Satoshi Yoshida and   
            Ryuji Ichihashi and   
                     Akio Toh-e   Ras recruits mitotic exit regulator Lte1
                                  to the bud cortex in budding yeast . . . 889
         Jonathan D. Violin and   
                  Jin Zhang and   
             Roger Y. Tsien and   
            Alexandra C. Newton   A genetically encoded fluorescent
                                  reporter reveals oscillatory
                                  phosphorylation by protein kinase C  . . 899
               Prithi Rajan and   
        David M. Panchision and   
            Laura F. Newell and   
             Ronald D. G. McKay   BMPs signal alternately through a SMAD
                                  or FRAP--STAT pathway to regulate fate
                                  choice in CNS stem cells . . . . . . . . 911
          Cameron L. Hoover and   
      Lutz G. W. Hilgenberg and   
                Martin A. Smith   The COOH-terminal domain of agrin
                                  signals via a synaptic receptor in
                                  central nervous system neurons . . . . . 923
             Paola Chiarugi and   
        Giovambattista Pani and   
             Elisa Giannoni and   
             Letizia Taddei and   
           Renata Colavitti and   
            Giovanni Raugei and   
                Mark Symons and   
            Silvia Borrello and   
           Tommaso Galeotti and   
             Giampietro Ramponi   Reactive oxygen species as essential
                                  mediators of cell adhesion . . . . . . . 933
             Yoshito Takeda and   
             Isao Tachibana and   
               Kenji Miyado and   
        Masatoshi Kobayashi and   
              Toru Miyazaki and   
          Toshiki Funakoshi and   
              Hiromi Kimura and   
            Hiroyuki Yamane and   
            Yoshiyuki Saito and   
              Hiroyuki Goto and   
             Tsutomu Yoneda and   
          Mitsuhiro Yoshida and   
               Toru Kumagai and   
              Tadashi Osaki and   
              Seiji Hayashi and   
              Ichiro Kawase and   
                  Eisuke Mekada   Tetraspanins CD9 and CD81 function to
                                  prevent the fusion of mononuclear
                                  phagocytes . . . . . . . . . . . . . . . 945
                 Yuko Iwata and   
            Yuki Katanosaka and   
                  Yuji Arai and   
             Kazuo Komamura and   
             Kunio Miyatake and   
             Munekazu Shigekawa   A novel mechanism of myocyte
                                  degeneration involving the
                                  Ca$^{2+}$-permeable growth
                                  factor--regulated channel  . . . . . . . 957
Francisco J. Martinez-Wittinghan and   
          Caterina Sellitto and   
                  Leping Li and   
               Xiaohua Gong and   
             Peter R. Brink and   
         Richard T. Mathias and   
                Thomas W. White   Dominant cataracts result from
                                  incongruous mixing of wild-type lens
                                  connexins  . . . . . . . . . . . . . . . 969
         Jennifer L. Genova and   
               Richard G. Fehon   Neuroglian, Gliotactin, and the Na$^+$
                                  /K$^+$ ATPase are essential for septate
                                  junction function in \bionameDrosophila  979
              Joost Schulte and   
              Ulrich Tepass and   
                Vanessa J. Auld   Gliotactin, a novel marker of
                                  tricellular junctions, is necessary for
                                  septate junction development in
                                  \bionameDrosophila . . . . . . . . . . . 991

Journal of Cell Biology
Volume 161, Number 6, June, 2003

              Nicole LeBrasseur   Two ways VEGF--A builds a vessel . . . . ??
              Nicole LeBrasseur   Catastrophe under pressure . . . . . . . ??
              Nicole LeBrasseur   E-cadherin immobilizes cells from the
                                  inside . . . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Golgi united are also divided  . . . . . ??
              Nicole LeBrasseur   NRG-1 talks back to neurons  . . . . . . ??
               William A. Wells   A tumorigenic culprit in ES cells  . . . ??
               William A. Wells   WASPs with memory  . . . . . . . . . . . ??
               William A. Wells   Helicobacter breaks down junctions . . . ??
               William A. Wells   Committing to mitosis  . . . . . . . . . ??
               William A. Wells   Anchored by feedback . . . . . . . . . . ??
             Morris J. Birnbaum   Lipolysis  . . . . . . . . . . . . . . . 1011
               Nica Borgese and   
               Sara Colombo and   
            Emanuela Pedrazzini   The tale of tail-anchored proteins . . . 1013
           Melinda M. Horne and   
             Thomas M. Guadagno   A requirement for MAP kinase in the
                                  assembly and maintenance of the mitotic
                                  spindle  . . . . . . . . . . . . . . . . 1021
           Marcel E. Janson and   
        Mathilde E. de Dood and   
              Marileen Dogterom   Dynamic instability of microtubules is
                                  regulated by force . . . . . . . . . . . 1029
     Vladimír Reiser and   
           Desmond C. Raitt and   
                    Haruo Saito   Yeast osmosensor Sln1 and plant
                                  cytokinin receptor Cre1 respond to
                                  changes in turgor pressure . . . . . . . 1035
           Sarah M. Wignall and   
        Renée Deehan and   
          Thomas J. Maresca and   
                  Rebecca Heald   The condensin complex is required for
                                  proper spindle assembly and chromosome
                                  segregation in \bionameXenopus egg
                                  extracts . . . . . . . . . . . . . . . . 1041
                Lisa Dailey and   
        Emmanuel Laplantine and   
            Riccardo Priore and   
               Claudio Basilico   A network of transcriptional and
                                  signaling events is activated by FGF to
                                  induce chondrocyte growth arrest and
                                  differentiation  . . . . . . . . . . . . 1053
             Keiji Uchiyama and   
              Eija Jokitalo and   
              Mervi Lindman and   
               Mark Jackman and   
                  Fumi Kano and   
            Masayuki Murata and   
             Xiaodong Zhang and   
                    Hisao Kondo   The localization and phosphorylation of
                                  p47 are important for Golgi
                                  disassembly--assembly during the cell
                                  cycle  . . . . . . . . . . . . . . . . . 1067
                Yuqing Dong and   
               David Pruyne and   
              Anthony Bretscher   Formin-dependent actin assembly is
                                  regulated by distinct modes of Rho
                                  signaling in yeast . . . . . . . . . . . 1081
            Carole Sztalryd and   
                 Guoheng Xu and   
              Heidi Dorward and   
             John T. Tansey and   
          Juan A. Contreras and   
             Alan R. Kimmel and   
             Constantine Londos   Perilipin A is essential for the
                                  translocation of hormone-sensitive
                                  lipase during lipolytic activation . . . 1093
            Thomas Herrmann and   
       Frank van der Hoeven and   
   Hermann-Josef Gröne and   
     Adrian Francis Stewart and   
              Lutz Langbein and   
                Iris Kaiser and   
           Gerhard Liebisch and   
             Isabella Gosch and   
         Florian Buchkremer and   
           Wolfgang Drobnik and   
               Gerd Schmitz and   
              Wolfgang Stremmel   Mice with targeted disruption of the
                                  fatty acid transport protein 4 (Fatp 4,
                                  Slc27a4) gene show features of lethal
                                  restrictive dermopathy . . . . . . . . . 1105
          Kyohei Umebayashi and   
                 Akihiko Nakano   Ergosterol is required for targeting of
                                  tryptophan permease to the yeast plasma
                                  membrane . . . . . . . . . . . . . . . . 1117
                Jianxin Bao and   
             Deon Wolpowitz and   
              Lorna W. Role and   
               David A. Talmage   Back signaling by the Nrg-1
                                  intracellular domain . . . . . . . . . . 1133
        Florence Niedergang and   
         Emma Colucci-Guyon and   
             Thierry Dubois and   
        Graça Raposo and   
              Philippe Chavrier   ADP ribosylation factor 6 is activated
                                  and controls membrane delivery during
                                  phagocytosis in macrophages  . . . . . . 1143
                  Haihua Gu and   
         Roberto J. Botelho and   
                     Min Yu and   
           Sergio Grinstein and   
               Benjamin G. Neel   Critical role for scaffolding adapter
                                  Gab2 in Fc$ \gamma $R-mediated
                                  phagocytosis . . . . . . . . . . . . . . 1151
            Holger Gerhardt and   
            Matthew Golding and   
           Marcus Fruttiger and   
        Christiana Ruhrberg and   
           Andrea Lundkvist and   
        Alexandra Abramsson and   
            Michael Jeltsch and   
       Christopher Mitchell and   
               Kari Alitalo and   
                David Shima and   
             Christer Betsholtz   VEGF guides angiogenic sprouting
                                  utilizing endothelial tip cell filopodia 1163
          Anthony Wayne Orr and   
         Claudio E. Pedraza and   
     Manuel Antonio Pallero and   
            Carrie A. Elzie and   
          Silvia Goicoechea and   
       Dudley K. Strickland and   
       Joanne E. Murphy-Ullrich   Low density lipoprotein
                                  receptor--related protein is a
                                  calreticulin coreceptor that signals
                                  focal adhesion disassembly . . . . . . . 1179
           Alice S. T. Wong and   
              Barry M. Gumbiner   Adhesion-independent mechanism for
                                  suppression of tumor cell invasion by
                                  E-cadherin . . . . . . . . . . . . . . . 1191


Journal of Cell Biology
Volume 162, Number 1, July, 2003

                   Alan W. Dove   Histones help clones forget their pasts  ??
                   Alan W. Dove   A fusion inhibitor on endosomes  . . . . ??
                   Alan W. Dove   Controlling flagellar strokes  . . . . . ??
                   Alan W. Dove   Splicing fibronectin's functions . . . . ??
                   Alan W. Dove   Hierarchical condensation  . . . . . . . ??
              Nicole LeBrasseur   Fibronectin for branching  . . . . . . . ??
              Nicole LeBrasseur   Spare the Mbl, spoil the rod?  . . . . . ??
              Nicole LeBrasseur   Remodeling the nucleus . . . . . . . . . ??
          Nicole LeBrasseur and   
              Nicole LeBrasseur   Glutamate in unusual places  . . . . . . ??
          Nicole LeBrasseur and   
              Nicole LeBrasseur   Dying cells say come-hither  . . . . . . ??
           Jonathan Pettitt and   
           Elisabeth A. Cox and   
           Ian D. Broadbent and   
               Aileen Flett and   
                    Jeff Hardin   The \bionameCaenorhabditis elegans p120
                                  catenin homologue, JAC-1, modulates
                                  cadherin--catenin function during
                                  epidermal morphogenesis  . . . . . . . . 15
            Yuri G. Strukov and   
                   Yan Wang and   
              Andrew S. Belmont   Engineered chromosome regions with
                                  altered sequence composition demonstrate
                                  hierarchical large-scale folding within
                                  metaphase chromosomes  . . . . . . . . . 23
               Jin-Moon Kim and   
                Honglin Liu and   
              Mayuko Tazaki and   
               Masao Nagata and   
                    Fugaku Aoki   Changes in histone acetylation during
                                  mouse oocyte meiosis . . . . . . . . . . 37
                Gerald Rupp and   
                 Mary E. Porter   A subunit of the dynein regulatory
                                  complex in Chlamydomonas is a homologue
                                  of a growth arrest--specific gene
                                  product  . . . . . . . . . . . . . . . . 47
              Wei-Xing Zong and   
                     Chi Li and   
     Georgia Hatzivassiliou and   
            Tullia Lindsten and   
               Qian-Chun Yu and   
               Junying Yuan and   
              Craig B. Thompson   Bax and Bak can localize to the
                                  endoplasmic reticulum to initiate
                                  apoptosis  . . . . . . . . . . . . . . . 59
                  Yihong Ye and   
             Hemmo H. Meyer and   
                Tom A. Rapoport   Function of the p97--Ufd1--Npl4 complex
                                  in retrotranslocation from the ER to the
                                  cytosol  . . . . . . . . . . . . . . . . 71
              Mitsuhiro Abe and   
             Hiroshi Qadota and   
                Aiko Hirata and   
                 Yoshikazu Ohya   Lack of GTP-bound Rho1p in secretory
                                  vesicles of \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 85
        Maria Cruz Martinez and   
            Tomoyo Ochiishi and   
           Michael Majewski and   
               Kenneth S. Kosik   Dual regulation of neuronal
                                  morphogenesis by a $ \delta
                                  $-catenin--cortactin complex and Rho . . 99
             Michael Krauss and   
            Masahiro Kinuta and   
             Markus R. Wenk and   
          Pietro De Camilli and   
                Kohji Takei and   
                  Volker Haucke   ARF6 stimulates clathrin/AP-2
                                  recruitment to synaptic membranes by
                                  activating phosphatidylinositol
                                  phosphate kinase type I$ \gamma $  . . . 113
                    Wei Sun and   
                   Qing Yan and   
             Thomas A. Vida and   
                 Andrew J. Bean   Hrs regulates early endosome fusion by
                                  inhibiting formation of an endosomal
                                  SNARE complex  . . . . . . . . . . . . . 125
          Leonieke Terpstra and   
    Josée Prud'homme and   
              Alice Arabian and   
                 Shu Takeda and   
     Gérard Karsenty and   
             Shoukat Dedhar and   
          René St-Arnaud   Reduced chondrocyte proliferation and
                                  chondrodysplasia in mice lacking the
                                  integrin-linked kinase in chondrocytes   139
      Andrés F. Muro and   
            Anil K. Chauhan and   
             Srecko Gajovic and   
        Alessandra Iaconcig and   
              Fabiola Porro and   
             Giorgio Stanta and   
           Francisco E. Baralle   Regulated splicing of the fibronectin
                                  EDA exon is essential for proper skin
                                  wound healing and normal lifespan  . . . 149

Journal of Cell Biology
Volume 162, Number 2, July, 2003

              Nicole LeBrasseur   Polyamines in inflammation . . . . . . . ??
              Nicole LeBrasseur   Desulfation on the cell surface  . . . . ??
              Nicole LeBrasseur   A building block of two organelles . . . ??
              Nicole LeBrasseur   Neural cells turn and run  . . . . . . . ??
              Nicole LeBrasseur   Kicking out antiviral proteins . . . . . ??
               William A. Wells   A loss, or two gains?  . . . . . . . . . ??
               William A. Wells   Nervous picket fences  . . . . . . . . . ??
               William A. Wells   Sticky transmission  . . . . . . . . . . ??
               William A. Wells   Activation by reduction  . . . . . . . . ??
               William A. Wells   Doing the CDC20 shuffle  . . . . . . . . ??
                Michael J. Held   Proposed legislation supports an
                                  untested publishing model  . . . . . . . 171
               Naoko Ohtani and   
               Paul Brennan and   
             Stefan Gaubatz and   
               Elaine Sanij and   
               Paul Hertzog and   
            Ernst Wolvetang and   
           Jacques Ghysdael and   
                Martin Rowe and   
                      Eiji Hara   Epstein--Barr virus LMP1 blocks
                                  p16$^{\rm INK4a}$-RB pathway by
                                  promoting nuclear export of E2F4/5 . . . 173
          Vangelis Kondylis and   
            Catherine Rabouille   A novel role for dp115 in the
                                  organization of tER sites in
                                  \bionameDrosophila . . . . . . . . . . . 185
             Ward C. Tucker and   
       J. Michael Edwardson and   
                 Jihong Bai and   
              Hyun-Jung Kim and   
        Thomas F. J. Martin and   
               Edwin R. Chapman   Identification of synaptotagmin
                                  effectors via acute inhibition of
                                  secretion from cracked PC12 cells  . . . 199
            Martin J. Bayer and   
            Christoph Reese and   
        Susanne Bühler and   
         Christopher Peters and   
                  Andreas Mayer   Vacuole membrane fusion  . . . . . . . . 211
        Hisayoshi Yoshizaki and   
                Yusuke Ohba and   
             Kazuo Kurokawa and   
              Reina E. Itoh and   
           Takeshi Nakamura and   
            Naoki Mochizuki and   
            Kazuo Nagashima and   
              Michiyuki Matsuda   Activity of Rho-family GTPases during
                                  cell division as visualized with
                                  FRET-based probes  . . . . . . . . . . . 223
      Catherine I. Dubreuil and   
          Matthew J. Winton and   
               Lisa McKerracher   Rho activation patterns after spinal
                                  cord injury and the role of activated
                                  Rho in apoptosis in the central nervous
                                  system . . . . . . . . . . . . . . . . . 233
             Louis K. Chang and   
          Robert E. Schmidt and   
              Eugene M. Johnson   Alternating metabolic pathways in
                                  NGF-deprived sympathetic neurons affect
                                  caspase-independent death  . . . . . . . 245
               Denis Soulet and   
                   Serge Rivest   Polyamines play a critical role in the
                                  control of the innate immune response in
                                  the mouse central nervous system . . . . 257
     Maria Elena De Bellard and   
                     Yi Rao and   
        Marianne Bronner-Fraser   Dual function of Slit2 in repulsion and
                                  enhanced migration of trunk, but not
                                  vagal, neural crest cells  . . . . . . . 269
        Jill K. Slack-Davis and   
             Scott T. Eblen and   
               Maja Zecevic and   
           Scott A. Boerner and   
           Adel Tarcsafalvi and   
              H. Bruce Diaz and   
           Mark S. Marshall and   
           Michael J. Weber and   
          J. Thomas Parsons and   
              Andrew D. Catling   PAK1 phosphorylation of MEK1 regulates
                                  fibronectin-stimulated MAPK activation   281
              Dong Min Shin and   
              Marlin Dehoff and   
                  Xiang Luo and   
            Shin Hyeok Kang and   
               Jiangchen Tu and   
          Surendra K. Nayak and   
            Elliott M. Ross and   
             Paul F. Worley and   
                 Shmuel Muallem   Homer 2 tunes G protein--coupled
                                  receptors stimulus intensity by
                                  regulating RGS proteins and PLC$ \beta $
                                  GAP activities . . . . . . . . . . . . . 293
                Guangwei Du and   
       Yelena M. Altshuller and   
             Nicolas Vitale and   
                 Ping Huang and   
   Sylvette Chasserot-Golaz and   
           Andrew J. Morris and   
         Marie-France Bader and   
             Michael A. Frohman   Regulation of phospholipase D1
                                  subcellular cycling through coordination
                                  of multiple membrane association motifs  305
         Tim-Wolf Gilberger and   
       Jennifer K. Thompson and   
            Michael B. Reed and   
             Robert T. Good and   
                 Alan F. Cowman   The cytoplasmic domain of the Plasmodium
                                  falciparum ligand EBA-175 is essential
                                  for invasion but not protein trafficking 317
                Xiaodong Xi and   
          Richard J. Bodnar and   
                  Zhenyu Li and   
          Stephen C.-T. Lam and   
                    Xiaoping Du   Critical roles for the COOH-terminal
                                  NITY and RGT sequences of the integrin $
                                  \beta_3 $ cytoplasmic domain in
                                  inside-out and outside-in signaling  . . 329
                 Xingbin Ai and   
                 Anh-Tri Do and   
              Olga Lozynska and   
     Marion Kusche-Gullberg and   
                Ulf Lindahl and   
             Charles P. Emerson   QSulf1 remodels the 6-O sulfation states
                                  of cell surface heparan sulfate
                                  proteoglycans to promote Wnt signaling   341

Journal of Cell Biology
Volume 162, Number 3, August, 2003

                   Alan W. Dove   When myosin heads go walking . . . . . . ??
                   Alan W. Dove   Schwann cells don caps, touch nodes  . . ??
                   Alan W. Dove   Neural progenitors play favorites  . . . ??
                   Alan W. Dove   A simple way to get cleavage . . . . . . ??
                   Alan W. Dove   Watching kinetochores sweat  . . . . . . ??
                    Rabiya Tuma   Cilia take charge in L--R asymmetry  . . ??
                    Rabiya Tuma   Network architecture determines
                                  stability  . . . . . . . . . . . . . . . ??
                    Rabiya Tuma   Exocytosis --- one vesicle at a time . . ??
                    Rabiya Tuma   The elusive cell cycle--transcription
                                  link . . . . . . . . . . . . . . . . . . ??
                    Rabiya Tuma   Loss of Rb launches cell cycle . . . . . ??
                    Eric C. Lai   Lipid rafts make for slippery platforms  365
                  Ali Amara and   
                 Dan R. Littman   After Hrs with HIV . . . . . . . . . . . 371
                Paul Maddox and   
             Aaron Straight and   
               Peg Coughlin and   
       Timothy J. Mitchison and   
               Edward D. Salmon   Direct observation of microtubule
                                  dynamics at kinetochores in
                                  \bionameXenopus extract spindles . . . . 377
           G. Bradley Alsop and   
                   Dahong Zhang   Microtubules are the only structural
                                  constituent of the spindle apparatus
                                  required for induction of cell cleavage  383
             Janna Bednenko and   
             Gino Cingolani and   
                   Larry Gerace   Importin $ \beta $ contains a
                                  COOH-terminal nucleoporin binding region
                                  important for nuclear transport  . . . . 391
            Pierre Morsomme and   
Cristina Prescianotto-Baschong and   
                 Howard Riezman   The ER v--SNAREs are required for
                                  GPI-anchored protein sorting from other
                                  secretory proteins upon exit from the ER 403
          David J. Katzmann and   
      Christopher J. Stefan and   
               Markus Babst and   
                   Scott D. Emr   Vps27 recruits ESCRT machinery to
                                  endosomes during MVB sorting . . . . . . 413
             Owen Pornillos and   
        Daniel S. Higginson and   
           Kirsten M. Stray and   
           Robert D. Fisher and   
         Jennifer E. Garrus and   
             Marielle Payne and   
               Gong-Ping He and   
             Hubert E. Wang and   
            Scott G. Morham and   
            Wesley I. Sundquist   HIV Gag mimics the Tsg101-recruiting
                                  activity of the human Hrs protein  . . . 425
            Kristi G. Bache and   
              Andreas Brech and   
                Anja Mehlum and   
                Harald Stenmark   Hrs regulates multivesicular body
                                  formation via ESCRT recruitment to
                                  endosomes  . . . . . . . . . . . . . . . 435
  Annegret Pelchen-Matthews and   
            Beatrice Kramer and   
                     Mark Marsh   Infectious HIV-1 assembles in late
                                  endosomes in primary macrophages . . . . 443
              Michael Kalai and   
           Mohamed Lamkanfi and   
          Geertrui Denecker and   
           Michael Boogmans and   
             Saskia Lippens and   
                  Ann Meeus and   
               Wim Declercq and   
             Peter Vandenabeele   Regulation of the expression and
                                  processing of caspase-12 . . . . . . . . 457
           Erhard Bieberich and   
            Sarah MacKinnon and   
                Jeane Silva and   
               Scott Noggle and   
                Brian G. Condie   Regulation of cell death in mitotic
                                  neural progenitor cells by asymmetric
                                  distribution of prostate apoptosis
                                  response 4 (PAR-4) and simultaneous
                                  elevation of endogenous ceramide . . . . 469
                Neil M. Kad and   
           Arthur S. Rovner and   
        Patricia M. Fagnant and   
          Peteranne B. Joel and   
             Guy G. Kennedy and   
           Joseph B. Patlak and   
           David M. Warshaw and   
             Kathleen M. Trybus   A mutant heterodimeric myosin with one
                                  inactive head generates maximal
                                  displacement . . . . . . . . . . . . . . 481
            Cheryl L. Gatto and   
          Barbara J. Walker and   
                Stephen Lambert   Local ERM activation and dynamic growth
                                  cones at Schwann cell tips implicated in
                                  efficient formation of nodes of Ranvier  489
             Roberta Faccio and   
          Deborah V. Novack and   
            Alberta Zallone and   
            F. Patrick Ross and   
           Steven L. Teitelbaum   Dynamic changes in the osteoclast
                                  cytoskeleton in response to growth
                                  factors and cell attachment are
                                  controlled by $ \beta $3 integrin  . . . 499
              Yvan Torrente and   
          Geoffrey Camirand and   
            Federica Pisati and   
            Marzia Belicchi and   
              Barbara Rossi and   
              Fabio Colombo and   
        Mosthapha El Fahime and   
           Nicolas J. Caron and   
         Andrew C. Issekutz and   
        Gabriela Constantin and   
        Jacques P. Tremblay and   
                 Nereo Bresolin   Identification of a putative pathway for
                                  the muscle homing of stem cells in a
                                  muscular dystrophy model . . . . . . . . 511

Journal of Cell Biology
Volume 162, Number 4, August, 2003

              Nicole LeBrasseur   Prions prefer caveosomes . . . . . . . . ??
              Nicole LeBrasseur   Stop and go L1CAM  . . . . . . . . . . . ??
              Nicole LeBrasseur   Synapse too exclusive for CD148  . . . . ??
              Nicole LeBrasseur   G-proteins for spindle geometry  . . . . ??
              Nicole LeBrasseur   BubR1 checks in with CENP--E . . . . . . ??
               William A. Wells   Pulling backwards  . . . . . . . . . . . ??
               William A. Wells   Reprogrammed by a frog . . . . . . . . . ??
               William A. Wells   Surviving heat through destruction . . . ??
               William A. Wells   My mother, the wave  . . . . . . . . . . ??
               William A. Wells   The checkpoint of death  . . . . . . . . ??
            Marta L. Hribal and   
                  Jun Nakae and   
          Tadahiro Kitamura and   
            John R. Shutter and   
                Domenico Accili   Regulation of insulin-like growth
                                  factor-dependent myoblast
                                  differentiation by Foxo forkhead
                                  transcription factors  . . . . . . . . . 535
     Sabyasachi Chakrabarti and   
        Koichi S. Kobayashi and   
         Richard A. Flavell and   
           Carolyn B. Marks and   
             Katsuya Miyake and   
            David R. Liston and   
         Kimberly T. Fowler and   
           Fred S. Gorelick and   
               Norma W. Andrews   Impaired membrane resealing and
                                  autoimmune myositis in synaptotagmin
                                  VII--deficient mice  . . . . . . . . . . 543
          Beth A. A. Weaver and   
            Zahid Q. Bonday and   
          Frances R. Putkey and   
        Geert J. P. L. Kops and   
              Alain D. Silk and   
               Don W. Cleveland   Centromere-associated protein--E is
                                  essential for the mammalian mitotic
                                  checkpoint to prevent aneuploidy due to
                                  single chromosome loss . . . . . . . . . 551
                 Keith Byrd and   
               Victor G. Corces   Visualization of chromatin domains
                                  created by the gypsy insulator of
                                  \bionameDrosophila . . . . . . . . . . . 565
         Elisabet C. Mandon and   
                 Ying Jiang and   
                   Reid Gilmore   Dual recognition of the ribosome and the
                                  signal recognition particle by the SRP
                                  receptor during protein targeting to the
                                  endoplasmic reticulum  . . . . . . . . . 575
             Claus Reimertz and   
           Donat Kögel and   
              Abdelhaq Rami and   
          Thomas Chittenden and   
             Jochen H. M. Prehn   Gene expression during ER
                                  stress--induced apoptosis in neurons . . 587
       Anthony J. Valentijn and   
        Anthony D. Metcalfe and   
                  Jane Kott and   
         Charles H. Streuli and   
              Andrew P. Gilmore   Spatial and temporal changes in Bax
                                  subcellular localization during anoikis  599
            Jonathan Gilley and   
             Paul J. Coffer and   
                   Jonathan Ham   FOXO transcription factors directly
                                  activate bim gene expression and promote
                                  apoptosis in sympathetic neurons . . . . 613
                 Fengwei Yu and   
                     Yu Cai and   
             Rachna Kaushik and   
              Xiaohang Yang and   
                   William Chia   Distinct roles of G$ \alpha $i and G$
                                  \beta $13F subunits of the
                                  heterotrimeric G protein complex in the
                                  mediation of \bionameDrosophila
                                  neuroblast asymmetric divisions  . . . . 623
             Xiang-Dong Gao and   
              Stefan Albert and   
    Serguei E. Tcheperegine and   
        Christopher G. Burd and   
            Dieter Gallwitz and   
                       Erfei Bi   The GAP activity of Msb3p and Msb4p for
                                  the Rab GTPase Sec4p is required for
                                  efficient exocytosis and actin
                                  organization . . . . . . . . . . . . . . 635
          Yoshikatsu Aikawa and   
            Thomas F. J. Martin   ARF6 regulates a plasma membrane pool of
                                  phosphatidylinositol(4,5)bisphosphate
                                  required for regulated exocytosis  . . . 647
       Cécile Vindis and   
       Douglas Pat Cerretti and   
           Thomas O. Daniel and   
                  Uyen Huynh-Do   EphB1 recruits c--Src and p52$^{\rm
                                  Shc}$ to activate MAPK/ERK and promote
                                  chemotaxis . . . . . . . . . . . . . . . 661
                 Joseph Lin and   
                   Arthur Weiss   The tyrosine phosphatase CD148 is
                                  excluded from the immunologic synapse
                                  and down-regulates prolonged T cell
                                  signaling  . . . . . . . . . . . . . . . 673
              Zeev Shmelzer and   
               Nurit Haddad and   
                Ester Admon and   
               Itai Pessach and   
             Thomas L. Leto and   
          Zahit Eitan-Hazan and   
         Michal Hershfinkel and   
                    Rachel Levy   Unique targeting of cytosolic
                                  phospholipase A$_2$ to plasma membranes
                                  mediated by the NADPH oxidase in
                                  phagocytes . . . . . . . . . . . . . . . 683
        David Padrón and   
              Ying Jie Wang and   
            Masaya Yamamoto and   
                  Helen Yin and   
                Michael G. Roth   Phosphatidylinositol phosphate
                                  $5$-kinase I$ \beta $ recruits AP-2 to
                                  the plasma membrane and regulates rates
                                  of constitutive endocytosis  . . . . . . 693
            Peter J. Peters and   
          Alexander Mironov and   
               David Peretz and   
         Elly van Donselaar and   
            Estelle Leclerc and   
              Susanne Erpel and   
        Stephen J. DeArmond and   
           Dennis R. Burton and   
      R. Anthony Williamson and   
                 Martin Vey and   
            Stanley B. Prusiner   Trafficking of prion proteins through a
                                  caveolae-mediated endosomal pathway  . . 703
             Orlando D. Gil and   
            Takeshi Sakurai and   
             Ann E. Bradley and   
               Marc Y. Fink and   
        Melanie R. Cassella and   
               James A. Kuo and   
              Dan P. Felsenfeld   Ankyrin binding mediates L1CAM
                                  interactions with static components of
                                  the cytoskeleton and inhibits retrograde
                                  movement of L1CAM on the cell surface    719
     Lawrence E. Goldfinger and   
                 Jaewon Han and   
         William B. Kiosses and   
               Alan K. Howe and   
               Mark H. Ginsberg   Spatial restriction of $ \alpha $4
                                  integrin phosphorylation regulates
                                  lamellipodial stability and $ \alpha $4$
                                  \beta $1-dependent cell migration  . . . 731

Journal of Cell Biology
Volume 162, Number 5, September, 2003

                   Alan W. Dove   Wnt separate ways, met later . . . . . . ??
                   Alan W. Dove   Linking formins to Arp2/3  . . . . . . . ??
                   Alan W. Dove   A prolific nucleator program . . . . . . ??
                   Alan W. Dove   Bcl-w buries its tail, lets cell die . . ??
                   Alan W. Dove   AP-2 gets demoted  . . . . . . . . . . . ??
              Nicole LeBrasseur   How cholesterol clogs the arteries . . . ??
              Nicole LeBrasseur   Lonely receptors kill cells  . . . . . . ??
              Nicole LeBrasseur   The healing power of Ron . . . . . . . . ??
              Nicole LeBrasseur   Nucleotides choose origins . . . . . . . ??
              Nicole LeBrasseur   Losing self-awareness  . . . . . . . . . ??
          Gilbert Weidinger and   
                Randall T. Moon   When Wnts antagonize Wnts  . . . . . . . 753
            Yasuhiko Terada and   
                Yumi Uetake and   
                 Ryoko Kuriyama   Interaction of Aurora--A and centrosomin
                                  at the microtubule-nucleating site in
                                  \bionameDrosophila and mammalian cells   757
     Mariko Sekiya-Kawasaki and   
          Aaron Chris Groen and   
        M. Jamie T. V. Cope and   
             Marko Kaksonen and   
           Hadiya A. Watson and   
                 Chao Zhang and   
            Kevan M. Shokat and   
           Beverly Wendland and   
           Kent L. McDonald and   
       J. Michael McCaffery and   
                David G. Drubin   Dynamic phosphoregulation of the
                                  cortical actin cytoskeleton and
                                  endocytic machinery revealed by
                                  real-time chemical genetic analysis  . . 765
             Sean D. Conner and   
               Sandra L. Schmid   Differential requirements for AP-2 in
                                  clathrin-mediated endocytosis  . . . . . 773
         Stephan J. Kempiak and   
               Shu-Chin Yip and   
         Jonathan M. Backer and   
              Jeffrey E. Segall   Local signaling by the EGF receptor  . . 781
              Justin Sturge and   
                Dirk Wienke and   
                  Lucy East and   
            Gareth E. Jones and   
                Clare M. Isacke   GPI-anchored uPAR requires Endo180 for
                                  rapid directional sensing during
                                  chemotaxis . . . . . . . . . . . . . . . 789
               Thierry Voet and   
                 Bodo Liebe and   
          Charlotte Labaere and   
              Peter Marynen and   
                Harry Scherthan   Telomere-independent homologue pairing
                                  and checkpoint escape of accessory ring
                                  chromosomes in male mouse meiosis  . . . 795
              Marion Cremer and   
         Katrin Küpper and   
              Babett Wagler and   
              Leah Wizelman and   
             Johann v. Hase and   
             Yanina Weiland and   
              Ludwika Kreja and   
            Joachim Diebold and   
        Michael R. Speicher and   
                  Thomas Cremer   Inheritance of gene density--related
                                  higher order chromatin arrangements in
                                  normal and tumor cell nuclei . . . . . . 809
             Susan A. Gerbi and   
        Anton V. Borovjagin and   
        Federico E. Odreman and   
             Thilo Sascha Lange   U4 snRNA nucleolar localization requires
                                  the NHPX/15.5-kD protein binding site
                                  but not Sm protein or U6 snRNA
                                  association  . . . . . . . . . . . . . . 821
               Qiping Zheng and   
                 Guang Zhou and   
                Roy Morello and   
                Yuqing Chen and   
        Xavier Garcia-Rojas and   
                    Brendan Lee   Type X collagen gene regulation by Runx2
                                  contributes directly to its hypertrophic
                                  chondrocyte--specific expression in vivo 833
             Theresa Jordan and   
                 Jinyuan Li and   
              Hongbin Jiang and   
              Joseph X. DiMario   Repression of slow myosin heavy chain 2
                                  gene expression in fast skeletal muscle
                                  fibers by muscarinic acetylcholine
                                  receptor and G$ \alpha $q signaling  . . 843
         Robert H. Carnahan and   
              Kathleen L. Gould   The PCH family protein, Cdc15p, recruits
                                  two F-actin nucleation pathways to
                                  coordinate cytokinetic actin ring
                                  formation in Schizosaccharomyces pombe   851
          Rüdiger Neef and   
       Christian Preisinger and   
        Josephine Sutcliffe and   
           Robert Kopajtich and   
              Erich A. Nigg and   
            Thomas U. Mayer and   
                Francis A. Barr   Phosphorylation of mitotic kinesin-like
                                  protein 2 by polo-like kinase 1 is
                                  required for cytokinesis . . . . . . . . 863
         Julie Wilson-Annan and   
       Lorraine A. O'Reilly and   
          Simon A. Crawford and   
            George Hausmann and   
       Jennifer G. Beaumont and   
              Loes P. Parma and   
                   Lin Chen and   
            Martin Lackmann and   
             Trevor Lithgow and   
              Mark G. Hinds and   
           Catherine L. Day and   
             Jerry M. Adams and   
              David C. S. Huang   Proapoptotic BH3-only proteins trigger
                                  membrane integration of prosurvival
                                  Bcl-w and neutralize its activity  . . . 877
          Trudi A. Westfall and   
              Ryan Brimeyer and   
                  Jen Twedt and   
                Jean Gladon and   
           Andrea Olberding and   
      Makoto Furutani-Seiki and   
             Diane C. Slusarski   Wnt-5/pipetail functions in vertebrate
                                  axis formation as a negative regulator
                                  of Wnt/$ \beta $-catenin activity  . . . 889
                Lilia Topol and   
              Xueyuan Jiang and   
                Hosoon Choi and   
          Lisa Garrett-Beal and   
           Peter J. Carolan and   
                    Yingzi Yang   Wnt-5a inhibits the canonical Wnt
                                  pathway by promoting GSK-3--independent
                                  $ \beta $-catenin degradation  . . . . . 899
              Alison Motley and   
         Nicholas A. Bright and   
       Matthew N. J. Seaman and   
           Margaret S. Robinson   Clathrin-mediated endocytosis in
                                  AP-2--depleted cells . . . . . . . . . . 909
      Michelle L. McWhorter and   
            Umrao R. Monani and   
       Arthur H. M. Burghes and   
           Christine E. Beattie   Knockdown of the survival motor neuron
                                  (Smn) protein in zebrafish causes
                                  defects in motor axon outgrowth and
                                  pathfinding  . . . . . . . . . . . . . . 919
               John D. Hood and   
            Ricardo Frausto and   
         William B. Kiosses and   
         Martin A. Schwartz and   
               David A. Cheresh   Differential $ \alpha $v
                                  integrin--mediated Ras--ERK signaling
                                  during two pathways of angiogenesis  . . 933

Journal of Cell Biology
Volume 162, Number 6, September, 2003

              Nicole LeBrasseur   We can deplete it, we have the
                                  technology . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   When nuclear proteins go mitotic . . . . ??
              Nicole LeBrasseur   The glue that builds bristles  . . . . . ??
              Nicole LeBrasseur   More order in DNA  . . . . . . . . . . . ??
              Nicole LeBrasseur   Finding the axon . . . . . . . . . . . . ??
               William A. Wells   When is a virus an exosome?  . . . . . . ??
               William A. Wells   Centromere errors get chewed out . . . . ??
               William A. Wells   Survival is sweet  . . . . . . . . . . . ??
               William A. Wells   A daughter's size is not critical  . . . ??
               William A. Wells   Pulling to the protease  . . . . . . . . ??
              Anton Burakov and   
           Elena Nadezhdina and   
           Boris Slepchenko and   
              Vladimir Rodionov   Centrosome positioning in interphase
                                  cells  . . . . . . . . . . . . . . . . . 963
                  A. Petiot and   
            J. Fauré and   
                H. Stenmark and   
                   J. Gruenberg   PI3P signaling regulates receptor
                                  sorting but not transport in the
                                  endosomal pathway  . . . . . . . . . . . 971
        Lindsay S. Shopland and   
           Carol V. Johnson and   
                  Meg Byron and   
                John McNeil and   
             Jeanne B. Lawrence   Clustering of multiple specific genes
                                  and gene-rich R-bands around SC-35
                                  domains  . . . . . . . . . . . . . . . . 981
              Davide Salina and   
               Paul Enarson and   
              J. B. Rattner and   
                    Brian Burke   Nup358 integrates nuclear envelope
                                  breakdown with kinetochore assembly  . . 991
              Gohta Goshima and   
                 Ronald D. Vale   The roles of microtubule-based motor
                                  proteins in mitosis  . . . . . . . . . . 1003
             Tim Raemaekers and   
          Katharina Ribbeck and   
        Joël Beaudouin and   
                Wim Annaert and   
              Mark Van Camp and   
           Ingrid Stockmans and   
                 Nico Smets and   
             Roger Bouillon and   
              Jan Ellenberg and   
                Geert Carmeliet   NuSAP, a novel microtubule-associated
                                  protein involved in mitotic spindle
                                  organization . . . . . . . . . . . . . . 1017
                Markus Rehm and   
   Heiko Düßmann and   
             Jochen H. M. Prehn   Real-time single cell analysis of
                                  Smac/DIABLO release during apoptosis . . 1031
               Takao Nakata and   
              Nobutaka Hirokawa   Microtubules provide directional cues
                                  for polarized axonal transport through
                                  interaction with kinesin motor head  . . 1045
              Ryan E. Mudry and   
           Cynthia N. Perry and   
          Meredith Richards and   
            Velia M. Fowler and   
              Carol C. Gregorio   The interaction of tropomodulin with
                                  tropomyosin stabilizes thin filaments in
                                  cardiac myocytes . . . . . . . . . . . . 1057
           Gregory M. Guild and   
       Patricia S. Connelly and   
             Linda Ruggiero and   
           Kelly A. Vranich and   
                Lewis G. Tilney   Long continuous actin bundles in
                                  \bionameDrosophila bristles are
                                  constructed by overlapping short
                                  filaments  . . . . . . . . . . . . . . . 1069
          Stephen L. Rogers and   
           Ursula Wiedemann and   
              Nico Stuurman and   
                 Ronald D. Vale   Molecular requirements for actin-based
                                  lamella formation in \bionameDrosophila
                                  S2 cells . . . . . . . . . . . . . . . . 1079
        Victoria C. Foletta and   
                Mei Ann Lim and   
        Juliana Soosairajah and   
             April P. Kelly and   
         Edouard G. Stanley and   
               Mark Shannon and   
                     Wei He and   
               Supratik Das and   
       Joan Massagué and   
                    Ora Bernard   Direct signaling by the BMP type II
                                  receptor via the cytoskeletal regulator
                                  LIMK1  . . . . . . . . . . . . . . . . . 1089
           Frantisek Sandor and   
                 Eicke Latz and   
                   Fabio Re and   
              Leisa Mandell and   
               Galina Repik and   
       Douglas T. Golenbock and   
              Terje Espevik and   
       Evelyn A. Kurt-Jones and   
              Robert W. Finberg   Importance of extra- and intracellular
                                  domains of TLR1 and TLR2 in NF$ \kappa
                                  $B signaling . . . . . . . . . . . . . . 1099
             Anna Cattelino and   
             Stefan Liebner and   
            Radiosa Gallini and   
            Adriana Zanetti and   
           Giovanna Balconi and   
           Alessandro Corsi and   
               Paolo Bianco and   
            Hartwig Wolburg and   
               Robert Moore and   
            Boussadia Oreda and   
                Rolf Kemler and   
              Elisabetta Dejana   The conditional inactivation of the $
                                  \beta $-catenin gene in endothelial
                                  cells causes a defective vascular
                                  pattern and increased vascular fragility 1111
          Bryony S. Wiseman and   
         Mark D. Sternlicht and   
               Leif R. Lund and   
      Caroline M. Alexander and   
                  Joni Mott and   
            Mina J. Bissell and   
               Paul Soloway and   
         Shigeyoshi Itohara and   
                      Zena Werb   Site-specific inductive and inhibitory
                                  activities of MMP-2 and MMP-3
                                  orchestrate mammary gland branching
                                  morphogenesis  . . . . . . . . . . . . . 1123
          Seumas McCroskery and   
                Mark Thomas and   
              Linda Maxwell and   
             Mridula Sharma and   
                  Ravi Kambadur   Myostatin negatively regulates satellite
                                  cell activation and self-renewal . . . . 1135
           Sebastian Poliak and   
            Daniela Salomon and   
             Hadas Elhanany and   
             Helena Sabanay and   
              Brent Kiernan and   
               Larysa Pevny and   
           Colin L. Stewart and   
                Xiaorong Xu and   
             Shing-Yan Chiu and   
              Peter Shrager and   
        Andrew J. W. Furley and   
                    Elior Peles   Juxtaparanodal clustering of Shaker-like
                                  K$^+$ channels in myelinated axons
                                  depends on Caspr2 and TAG-1  . . . . . . 1149
                Maria Traka and   
        Laurence Goutebroze and   
          Natalia Denisenko and   
                Maria Bessa and   
            Artemisia Nifli and   
              Sophia Havaki and   
           Yoichiro Iwakura and   
        Fumihiko Fukamauchi and   
          Kazutada Watanabe and   
              Betty Soliven and   
       Jean-Antoine Girault and   
               Domna Karagogeos   Association of TAG-1 with Caspr2 is
                                  essential for the molecular organization
                                  of juxtaparanodal regions of myelinated
                                  fibers . . . . . . . . . . . . . . . . . 1161

Journal of Cell Biology
Volume 162, Number 7, September, 2003

                   Alan W. Dove   Getting lamin B1 processed and organized ??
                   Alan W. Dove   How to block botox . . . . . . . . . . . ??
                   Alan W. Dove   NgCAM takes a scenic route to the axon   ??
                   Alan W. Dove   A long version of Short stop . . . . . . ??
                   Alan W. Dove   Pop goes the acrosome  . . . . . . . . . ??
              Nicole LeBrasseur   Evolution steps back . . . . . . . . . . ??
              Nicole LeBrasseur   Translocon . . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Centrosomes lead stem cell orientation   ??
              Nicole LeBrasseur   Grow wings for a limited time only . . . ??
              Nicole LeBrasseur   Keratin for supple cells . . . . . . . . ??
           Jennifer H. Shin and   
               L. Mahadevan and   
      Guillermina S. Waller and   
             Knut Langsetmo and   
                Paul Matsudaira   Stored elastic energy powers the 60-$
                                  \mu $ m extension of the Limulus
                                  polyphemus sperm actin bundle  . . . . . 1183
   Laurent Gagnoux-Palacios and   
               Michael Dans and   
           Wouter van't Hof and   
            Agnese Mariotti and   
                Angela Pepe and   
         Guerrino Meneguzzi and   
            Marilyn D. Resh and   
           Filippo G. Giancotti   Compartmentalization of integrin $
                                  \alpha $6$ \beta $4 signaling in lipid
                                  rafts  . . . . . . . . . . . . . . . . . 1189
          Albert R. Davalos and   
                 Judith Campisi   Bloom syndrome cells undergo
                                  p53-dependent apoptosis and delayed
                                  assembly of BRCA1 and NBS1 repair
                                  complexes at stalled replication forks   1197
              John V. Kilmartin   Sfi1p has conserved centrin-binding
                                  sites and an essential function in
                                  budding yeast spindle pole body
                                  duplication  . . . . . . . . . . . . . . 1211
       Christopher P. Maske and   
     Michael S. Hollinshead and   
            Niall C. Higbee and   
            Martin O. Bergo and   
           Stephen G. Young and   
                  David J. Vaux   A carboxyl-terminal interaction of lamin
                                  B1 is dependent on the CAAX endoprotease
                                  Rce1 and carboxymethylation  . . . . . . 1223
           Daniel R. Larson and   
                  Yu May Ma and   
             Volker M. Vogt and   
                   Watt W. Webb   Direct measurement of Gag--Gag
                                  interaction during retrovirus assembly
                                  with FRET and fluorescence correlation
                                  spectroscopy . . . . . . . . . . . . . . 1233
                Misty Moore and   
           Robyn L. Goforth and   
                Hiroki Mori and   
                    Ralph Henry   Functional interaction of chloroplast
                                  SRP/FtsY with the ALB3 translocase in
                                  thylakoids . . . . . . . . . . . . . . . 1245
                   Tong Guo and   
               Yuriy Y. Kit and   
           Jean-Marc Nicaud and   
      Marie-Therese Le Dall and   
             S. Kelly Sears and   
            Hojatollah Vali and   
                 Honey Chan and   
     Richard A. Rachubinski and   
          Vladimir I. Titorenko   Peroxisome division in the yeast
                                  \bionameYarrowia lipolytica is regulated
                                  by a signal from inside the peroxisome   1255
      Jorge Santos Da Silva and   
              Miguel Medina and   
            Cecilia Zuliani and   
           Alessia Di Nardo and   
               Walter Witke and   
                Carlos G. Dotti   RhoA/ROCK regulation of neuritogenesis
                                  via profilin IIa-mediated control of
                                  actin stability  . . . . . . . . . . . . 1267
                   Hui Miao and   
        Christian H. Nickel and   
           Lloyd G. Cantley and   
        Leslie A. Bruggeman and   
          Laura N. Bennardo and   
                 Bingcheng Wang   EphA kinase activation regulates
                                  HGF-induced epithelial branching
                                  morphogenesis  . . . . . . . . . . . . . 1281
                   Min Dong and   
          David A. Richards and   
       Michael C. Goodnough and   
            William H. Tepp and   
            Eric A. Johnson and   
               Edwin R. Chapman   Synaptotagmins I and II mediate entry of
                                  botulinum neurotoxin B into cells  . . . 1293
           Katja Röper and   
              Nicholas H. Brown   Maintaining epithelial integrity . . . . 1305
               Dolora Wisco and   
           Eric D. Anderson and   
           Michael C. Chang and   
               Caren Norden and   
              Tatiana Boiko and   
          Heike Fölsch and   
               Bettina Winckler   Uncovering multiple axonal targeting
                                  pathways in hippocampal neurons  . . . . 1317


Journal of Cell Biology
Volume 163, Number 1, October, 2003

              Nicole LeBrasseur   Heparin sustains the brain . . . . . . . ??
              Nicole LeBrasseur   Recycling endosomes  . . . . . . . . . . ??
              Nicole LeBrasseur   To kill a brain cell . . . . . . . . . . ??
              Nicole LeBrasseur   Integrin is on uPAR to unleash cells . . ??
              Nicole LeBrasseur   Choreographing telomeres . . . . . . . . ??
               William A. Wells   One crossover is enough  . . . . . . . . ??
               William A. Wells   The sex--love connection . . . . . . . . ??
               William A. Wells   Prions by activation not amyloid . . . . ??
               William A. Wells   Neurons that swell . . . . . . . . . . . ??
               William A. Wells   Ready to replicate? So vesiculate! . . . ??
  Oscar Fernandez-Capetillo and   
                 Bodo Liebe and   
            Harry Scherthan and   
       André Nussenzweig   H2AX regulates meiotic telomere
                                  clustering . . . . . . . . . . . . . . . 15
                 Xinrong Fu and   
               Christine Ng and   
               Daorong Feng and   
                     Chun Liang   Cdc48p is required for the cell cycle
                                  commitment point at Start via
                                  degradation of the G1-CDK inhibitor
                                  Far1p  . . . . . . . . . . . . . . . . . 21
                 Yuzhi Chen and   
                 Wenyun Liu and   
            Donna L. McPhie and   
            Linda Hassinger and   
                Rachael L. Neve   APP-BP1 mediates APP-induced apoptosis
                                  and DNA synthesis and is increased in
                                  Alzheimer's disease brain  . . . . . . . 27
           Gottfried Eisner and   
            Hans-Georg Koch and   
             Konstanze Beck and   
             Joseph Brunner and   
           Matthias Müller   Ligand crowding at a nascent signal
                                  sequence . . . . . . . . . . . . . . . . 35
                Masato Yano and   
            Kazutoyo Terada and   
                  Masataka Mori   AIP is a mitochondrial import mediator
                                  that binds to both import receptor Tom20
                                  and preproteins  . . . . . . . . . . . . 45
           Matthew Heidtman and   
          Catherine Z. Chen and   
            Ruth N. Collins and   
                Charles Barlowe   A role for Yip1p in COPII vesicle
                                  biogenesis . . . . . . . . . . . . . . . 57
              Ssang-Goo Cho and   
                Jin Woo Kim and   
               Yong Hee Lee and   
             Hyun Sub Hwang and   
                Mi-Sung Kim and   
              Kanghyun Ryoo and   
              Myung Jin Kim and   
              Kyung Tae Noh and   
              Eun Kyung Kim and   
                 Jun-Ho Cho and   
            Kyoung Wan Yoon and   
              Eun-Gyung Cho and   
               Hee-Sae Park and   
              Sung Wook Chi and   
                Min-Jae Lee and   
              Sang Sun Kang and   
            Hidenori Ichijo and   
                    Eui-Ju Choi   Identification of a novel antiapoptotic
                                  protein that antagonizes ASK1 and CAD
                                  activities . . . . . . . . . . . . . . . 71
               Ming-Sum Lee and   
               Shih-Chu Kao and   
          Cynthia A. Lemere and   
                Weiming Xia and   
           Huang-Chun Tseng and   
                  Ying Zhou and   
               Rachael Neve and   
      Michael K. Ahlijanian and   
                   Li-Huei Tsai   APP processing is regulated by
                                  cytoplasmic phosphorylation  . . . . . . 83
            Zoe Scholefield and   
             Edwin A. Yates and   
               Gareth Wayne and   
             Augustin Amour and   
           William McDowell and   
             Jeremy E. Turnbull   Heparan sulfate regulates amyloid
                                  precursor protein processing by BACE1,
                                  the Alzheimer's $ \beta $-secretase  . . 97
                   Hui Zhou and   
                 Fengli Cao and   
               Zhishan Wang and   
                Zhao-Xue Yu and   
            Huu-Phuc Nguyen and   
                  Joy Evans and   
                 Shi-Hua Li and   
                  Xiao-Jiang Li   Huntingtin forms toxic NH$_2$-terminal
                                  fragment complexes that are promoted by
                                  the age-dependent decrease in proteasome
                                  activity . . . . . . . . . . . . . . . . 109
              Nancy A. Rice and   
             Leslie A. Leinwand   Skeletal myosin heavy chain function in
                                  cultured lung myofibroblasts . . . . . . 119
          Stanislav Samarin and   
     Stéphane Romero and   
            Christine Kocks and   
            Dominique Didry and   
        Dominique Pantaloni and   
           Marie-France Carlier   How VASP enhances actin-based motility   131
                Blake Riggs and   
             Wendy Rothwell and   
               Sarah Mische and   
       Gilles R. X. Hickson and   
           Johanne Matheson and   
             Thomas S. Hays and   
              Gwyn W. Gould and   
               William Sullivan   Actin cytoskeleton remodeling during
                                  early \bionameDrosophila furrow
                                  formation requires recycling endosomal
                                  components Nuclear-fallout and Rab11 . . 143
Fernando Martín-Belmonte and   
José A. Martínez-Menárguez and   
             Juan F. Aranda and   
       José Ballesta and   
   María C. de Marco and   
               Miguel A. Alonso   MAL regulates clathrin-mediated
                                  endocytosis at the apical surface of
                                  Madin--Darby canine kidney cells . . . . 155
             Masaki Shigeta and   
              Noriko Sanzen and   
             Masayuki Ozawa and   
                 Jianguo Gu and   
           Hitoshi Hasegawa and   
            Kiyotoshi Sekiguchi   CD151 regulates epithelial cell--cell
                                  adhesion through PKC- and
                                  Cdc42-dependent actin cytoskeletal
                                  reorganization . . . . . . . . . . . . . 165
                 Feng Zhang and   
            Clifford C. Tom and   
         Matthias C. Kugler and   
            Tsui-Ting Ching and   
        Jordan A. Kreidberg and   
                   Ying Wei and   
              Harold A. Chapman   Distinct ligand binding sites in
                                  integrin $ \alpha $3$ \beta $1 regulate
                                  matrix adhesion and cell--cell contact   177

Journal of Cell Biology
Volume 163, Number 2, October, 2003

                   Alan W. Dove   Weaklings unite to reorganize cell . . . ??
                   Alan W. Dove   Getting specific about polarized sorting ??
                   Alan W. Dove   An early warning system for DNA damage   ??
                   Alan W. Dove   A close look at cerebellar learning  . . ??
                   Alan W. Dove   Laminin-2 on the brain . . . . . . . . . ??
              Nicole LeBrasseur   Desmosomes in a tangle . . . . . . . . . ??
              Nicole LeBrasseur   Flies fight famine . . . . . . . . . . . ??
              Nicole LeBrasseur   The kinase knows . . . . . . . . . . . . ??
              Nicole LeBrasseur   Transcription keeps it simple  . . . . . ??
              Nicole LeBrasseur   Binding takes cooperation  . . . . . . . ??
                Linton M. Traub   Sorting it out . . . . . . . . . . . . . 203
          Michael S. Pepper and   
                  Mihaela Skobe   Lymphatic endothelium  . . . . . . . . . 209
          Stefan Westermann and   
          Iain M. Cheeseman and   
             Scott Anderson and   
              John R. Yates and   
            David G. Drubin and   
                Georjana Barnes   Architecture of the budding yeast
                                  kinetochore reveals a conserved
                                  molecular core . . . . . . . . . . . . . 215
                Jia-Jia Liu and   
              Jianqing Ding and   
           Anthony S. Kowal and   
            Timothy Nardine and   
            Elizabeth Allen and   
    Jean-Dominique Delcroix and   
               Chengbiao Wu and   
             William Mobley and   
               Elaine Fuchs and   
                    Yanmin Yang   BPAG1n4 is essential for retrograde
                                  axonal transport in sensory neurons  . . 223
          Antony P. Jackson and   
            Alexander Flett and   
                Carl Smythe and   
             Lindsay Hufton and   
            Frank R. Wettey and   
               Elizabeth Smythe   Clathrin promotes incorporation of cargo
                                  into coated pits by activation of the
                                  AP2 adaptor $ \mu $2 kinase  . . . . . . 231
       Patricia S. Bilodeau and   
     Stanley C. Winistorfer and   
         William R. Kearney and   
        Andrew D. Robertson and   
                Robert C. Piper   Vps27-Hse1 and ESCRT--I complexes
                                  cooperate to increase efficiency of
                                  sorting ubiquitinated proteins at the
                                  endosome . . . . . . . . . . . . . . . . 237
          Matthew P. Stokes and   
             W. Matthew Michael   DNA damage-induced replication arrest in
                                  \bionameXenopus egg extracts . . . . . . 245
              Erik L. Snapp and   
         Ramanujan S. Hegde and   
           Maura Francolini and   
         Francesca Lombardo and   
               Sara Colombo and   
        Emanuela Pedrazzini and   
               Nica Borgese and   
   Jennifer Lippincott-Schwartz   Formation of stacked ER cisternae by low
                                  affinity protein interactions  . . . . . 257
       Julia V. Gerasimenko and   
            Yoshio Maruyama and   
                Kojiro Yano and   
             Nick J. Dolman and   
          Alexei V. Tepikin and   
            Ole H. Petersen and   
            Oleg V. Gerasimenko   NAADP mobilizes Ca$^{2+}$ from a
                                  thapsigargin-sensitive store in the
                                  nuclear envelope by activating ryanodine
                                  receptors  . . . . . . . . . . . . . . . 271
          Natalia Cheshenko and   
          Brian Del Rosario and   
                 Craig Woda and   
          Daniel Marcellino and   
             Lisa M. Satlin and   
                Betsy C. Herold   Herpes simplex virus triggers activation
                                  of calcium-signaling pathways  . . . . . 283
                Robert Feil and   
              Jana Hartmann and   
                Chongde Luo and   
         Wiebke Wolfsgruber and   
             Karl Schilling and   
               Susanne Feil and   
         Jaroslaw J. Barski and   
              Michael Meyer and   
            Arthur Konnerth and   
          Chris I. De Zeeuw and   
                  Franz Hofmann   Impairment of LTD and cerebellar
                                  learning by Purkinje cell--specific
                                  ablation of cGMP-dependent protein
                                  kinase I . . . . . . . . . . . . . . . . 295
              Silvia Parisi and   
           Daniela D'Andrea and   
            Carmine T. Lago and   
          Eileen D. Adamson and   
       M. Graziella Persico and   
           Gabriella Minchiotti   Nodal-dependent Cripto signaling
                                  promotes cardiomyogenesis and redirects
                                  the neural fate of embryonic stem cells  303
            Jayanta Debnath and   
        Stephanie J. Walker and   
                 Joan S. Brugge   Akt activation disrupts mammary acinar
                                  architecture and enhances proliferation
                                  in an mTOR-dependent manner  . . . . . . 315
               Pauline Wong and   
             Pierre A. Coulombe   Loss of keratin 6 (K6) proteins reveals
                                  a function for intermediate filaments
                                  during wound repair  . . . . . . . . . . 327
              Agnes Lee Ang and   
          Heike Fölsch and   
        Ulla-Maija Koivisto and   
               Marc Pypaert and   
                    Ira Mellman   The Rab8 GTPase selectively regulates
                                  AP-1B-dependent basolateral transport in
                                  polarized Madin--Darby canine kidney
                                  cells  . . . . . . . . . . . . . . . . . 339
          Heike Fölsch and   
               Marc Pypaert and   
               Sandra Maday and   
         Laurence Pelletier and   
                    Ira Mellman   The AP-1A and AP-1B clathrin adaptor
                                  complexes define biochemically and
                                  functionally distinct membrane domains   351
         Charles J. Russell and   
            Karen L. Kantor and   
      Theodore S. Jardetzky and   
                 Robert A. Lamb   A dual-functional paramyxovirus F
                                  protein regulatory switch segment  . . . 363
             Yong-Kook Kwon and   
            Hyeung-Jin Jang and   
                Sutapa Kole and   
                 Hua-Jun He and   
                 Michel Bernier   Role of the pleckstrin homology domain
                                  of PLC$ \gamma $1 in its interaction
                                  with the insulin receptor  . . . . . . . 375
                    Jing Du and   
                Linyin Feng and   
             Eugene Zaitsev and   
                Hyun-Soo Je and   
                 Xu-wen Liu and   
                         Bai Lu   Regulation of TrkB receptor tyrosine
                                  kinase and its internalization by
                                  neuronal activity and Ca$^{2+}$ influx   385
               Soo Jin Chun and   
         Matthew N. Rasband and   
          Richard L. Sidman and   
              Amyn A. Habib and   
              Timothy Vartanian   Integrin-linked kinase is required for
                                  laminin-$2$--induced oligodendrocyte
                                  cell spreading and CNS myelination . . . 397
    Grégory Giannone and   
              Guoying Jiang and   
          Deborah H. Sutton and   
         David R. Critchley and   
              Michael P. Sheetz   Talin1 is critical for force-dependent
                                  reinforcement of initial
                                  integrin--cytoskeleton bonds but not
                                  tyrosine kinase activation . . . . . . . 409

Journal of Cell Biology
Volume 163, Number 3, November, 2003

              Nicole LeBrasseur   BMP in a hairy situation . . . . . . . . ??
              Nicole LeBrasseur   ROCK and Rho in $3$D . . . . . . . . . . ??
              Nicole LeBrasseur   Where mtDNA is made  . . . . . . . . . . ??
              Nicole LeBrasseur   Forcing cells to stick around  . . . . . ??
              Nicole LeBrasseur   Quick cartilage transformation . . . . . ??
               William A. Wells   Passing along polarity . . . . . . . . . ??
               William A. Wells   A kinase that activates by occupancy . . ??
               William A. Wells   How to renew a stem cell . . . . . . . . ??
               William A. Wells   Latching onto fibrinogen . . . . . . . . ??
               William A. Wells   Damage first; infect later . . . . . . . ??
                Mark Peifer and   
                   Alpha S. Yap   Traffic control  . . . . . . . . . . . . 437
                Rosario Rizzuto   Calcium mobilization from mitochondria
                                  in synaptic transmitter release  . . . . 441
                 Ronald D. Vale   Myosin V motor proteins  . . . . . . . . 445
          Eileen T. O'Toole and   
           Kent L. McDonald and   
          Jana Mäntler and   
        J. Richard McIntosh and   
           Anthony A. Hyman and   
    Thomas Müller-Reichert   Morphologically distinct microtubule
                                  ends in the mitotic centrosome of
                                  \bionameCaenorhabditis elegans . . . . . 451
           Brett A. Kaufman and   
            Jill E. Kolesar and   
          Philip S. Perlman and   
                Ronald A. Butow   A function for the mitochondrial
                                  chaperonin Hsp60 in the structure and
                                  transmission of mitochondrial DNA
                                  nucleoids in \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 457
            Tiziana Bisogno and   
               Fiona Howell and   
            Gareth Williams and   
            Alberto Minassi and   
        Maria Grazia Cascio and   
           Alessia Ligresti and   
              Isabel Matias and   
   Aniello Schiano-Moriello and   
               Praveen Paul and   
         Emma-Jane Williams and   
            Uma Gangadharan and   
                 Carl Hobbs and   
          Vincenzo Di Marzo and   
                Patrick Doherty   Cloning of the first sn1-DAG lipases
                                  points to the spatial and temporal
                                  regulation of endocannabinoid signaling
                                  in the brain . . . . . . . . . . . . . . 463
            Satoru Yamazaki and   
                Ryo Iwamoto and   
               Kazuko Saeki and   
           Masanori Asakura and   
            Seiji Takashima and   
             Ayano Yamazaki and   
                Rina Kimura and   
           Hiroto Mizushima and   
              Hiroki Moribe and   
        Shigeki Higashiyama and   
             Masayuki Endoh and   
            Yasufumi Kaneda and   
             Satoshi Takagi and   
              Satoshi Itami and   
               Naoki Takeda and   
                 Gen Yamada and   
                  Eisuke Mekada   Mice with defects in HB--EGF ectodomain
                                  shedding show severe developmental
                                  abnormalities  . . . . . . . . . . . . . 469
             Yoshiaki Azuma and   
           Alexei Arnaoutov and   
                     Mary Dasso   SUMO-2\slash 3 regulates topoisomerase
                                  II in mitosis  . . . . . . . . . . . . . 477
              Daisuke Nanba and   
              Akiko Mammoto and   
             Koji Hashimoto and   
            Shigeki Higashiyama   Proteolytic release of the
                                  carboxy-terminal fragment of proHB--EGF
                                  causes nuclear export of PLZF  . . . . . 489
             Shelly Meeusen and   
                   Jodi Nunnari   Evidence for a two membrane--spanning
                                  autonomous mitochondrial DNA replisome   503
                  Feng Yang and   
              Xiang-ping He and   
              James Russell and   
                         Bai Lu   Ca$^{2+}$ influx-independent synaptic
                                  potentiation mediated by mitochondrial
                                  Na$^+$--Ca$^{2+}$ exchanger and protein
                                  kinase C . . . . . . . . . . . . . . . . 511
           Michael A. Davis and   
            Renee C. Ireton and   
             Albert B. Reynolds   A core function for p120-catenin in
                                  cadherin turnover  . . . . . . . . . . . 525
                Kanyan Xiao and   
           David F. Allison and   
        Kathleen M. Buckley and   
         Margaret D. Kottke and   
           Peter A. Vincent and   
             Victor Faundez and   
            Andrew P. Kowalczyk   Cellular levels of p120 catenin function
                                  as a set point for cadherin expression
                                  levels in microvascular endothelial
                                  cells  . . . . . . . . . . . . . . . . . 535
                 Xinyu Chen and   
         Shin-ichiro Kojima and   
             Gary G. Borisy and   
              Kathleen J. Green   p120 catenin associates with kinesin and
                                  facilitates the transport of
                                  cadherin--catenin complexes to
                                  intercellular junctions  . . . . . . . . 547
              Claire Desnos and   
Jean-Sébastien Schonn and   
      Sébastien Huet and   
           Viet Samuel Tran and   
            Aziz El-Amraoui and   
        Graça Raposo and   
            Isabelle Fanget and   
          Catherine Chapuis and   
Gaël Ménasché and   
Genevi\`eve de Saint Basile and   
            Christine Petit and   
             Sophie Cribier and   
          Jean-Pierre Henry and   
        François Darchen   Rab27A and its effector MyRIP link
                                  secretory granules to F-actin and
                                  control their motion towards release
                                  sites  . . . . . . . . . . . . . . . . . 559
                    Ling Su and   
             Joyce M. Agati and   
               Sarah J. Parsons   p190RhoGAP is cell cycle regulated and
                                  affects cytokinesis  . . . . . . . . . . 571
         Michele A. Wozniak and   
              Radhika Desai and   
         Patricia A. Solski and   
            Channing J. Der and   
              Patricia J. Keely   ROCK-generated contractility regulates
                                  breast epithelial cell differentiation
                                  in response to the physical properties
                                  of a three-dimensional collagen matrix   583
                 Lai-Wa Tam and   
         William L. Dentler and   
               Paul A. Lefebvre   Defective flagellar assembly and length
                                  regulation in LF3 null mutants in
                                  Chlamydomonas  . . . . . . . . . . . . . 597
         Krzysztof Kobielak and   
          H. Amalia Pasolli and   
               Laura Alonso and   
                 Lisa Polak and   
                   Elaine Fuchs   Defining BMP functions in the hair
                                  follicle by conditional ablation of BMP
                                  receptor IA  . . . . . . . . . . . . . . 609
                Bart De Cat and   
         Sin-Ya Muyldermans and   
          Christien Coomans and   
           Gis\`ele Degeest and   
  Bernadette Vanderschueren and   
              John Creemers and   
Frédéric Biemar and   
              Bernard Peers and   
                    Guido David   Processing by proprotein convertases is
                                  required for glypican-3 modulation of
                                  cell survival, Wnt signaling, and
                                  gastrulation movements . . . . . . . . . 625
          Benjamin L. Allen and   
              Alan C. Rapraeger   Spatial and temporal expression of
                                  heparan sulfate in mouse development
                                  regulates FGF and FGF receptor assembly  637
                  Oren Dwir and   
              Ariel Solomon and   
              Shmuel Mangan and   
         Geoffrey S. Kansas and   
          Ulrich S. Schwarz and   
                     Ronen Alon   Avidity enhancement of L-selectin bonds
                                  by flow  . . . . . . . . . . . . . . . . 649
              Kenn Holmbeck and   
               Paolo Bianco and   
          Kali Chrysovergis and   
               Susan Yamada and   
        Henning Birkedal-Hansen   MT1-MMP-dependent, apoptotic remodeling
                                  of unmineralized cartilage . . . . . . . 661

Journal of Cell Biology
Volume 163, Number 4, November, 2003

               William A. Wells   Held back by a finger  . . . . . . . . . ??
               William A. Wells   Cautious apoptosis . . . . . . . . . . . ??
               William A. Wells   A disease of actin transport?  . . . . . ??
               William A. Wells   Notch gets transformed . . . . . . . . . ??
               William A. Wells   Barriers to export . . . . . . . . . . . ??
              Nicole LeBrasseur   Tearing down the spindle . . . . . . . . ??
              Nicole LeBrasseur   Receptors make a quick exit  . . . . . . ??
              Nicole LeBrasseur   Immune cells take in unknown enemies . . ??
              Nicole LeBrasseur   Fold me or leave me  . . . . . . . . . . ??
              Nicole LeBrasseur   Fusion gets in the groove  . . . . . . . ??
                 Linda Wordeman   Breathing down the neck of Unc104  . . . 693
                Chan Nguyen and   
                  James A. Bibb   Cdk5 and the mystery of synaptic vesicle
                                  endocytosis  . . . . . . . . . . . . . . 697
                 Peggy Roth and   
          Nikos Xylourgidis and   
              Nafiseh Sabri and   
                    Anne Uv and   
           Maarten Fornerod and   
            Christos Samakovlis   The \bionameDrosophila nucleoporin
                                  DNup88 localizes DNup214 and CRM1 on the
                                  nuclear envelope and attenuates
                                  NES-mediated nuclear export  . . . . . . 701
           Kaye N. Truscott and   
              Wolfgang Voos and   
             Ann E. Frazier and   
                 Maria Lind and   
                 Yanfeng Li and   
           Andreas Geissler and   
                  Jan Dudek and   
          Hanne Müller and   
            Albert Sickmann and   
            Helmut E. Meyer and   
            Chris Meisinger and   
             Bernard Guiard and   
              Peter Rehling and   
               Nikolaus Pfanner   A J-protein is an essential subunit of
                                  the presequence translocase--associated
                                  protein import motor of mitochondria . . 707
     Dermott W. O'Callaghan and   
          Alexei V. Tepikin and   
             Robert D. Burgoyne   Dynamics and calcium sensitivity of the
                                  Ca$^{2+}$ /myristoyl switch protein
                                  hippocalcin in living cells  . . . . . . 715
           Andries Blokzijl and   
          Camilla Dahlqvist and   
              Eva Reissmann and   
                  Anna Falk and   
           Annalena Moliner and   
              Urban Lendahl and   
 Carlos F. Ibáñez   Cross-talk between the Notch and TGF-$
                                  \beta $ signaling pathways mediated by
                                  interaction of the Notch intracellular
                                  domain with Smad3  . . . . . . . . . . . 723
              Kristen Stead and   
           Cristina Aguilar and   
            Theresa Hartman and   
             Melissa Drexel and   
               Pamela Meluh and   
                 Vincent Guacci   Pds5p regulates the maintenance of
                                  sister chromatid cohesion and is
                                  sumoylated to promote the dissolution of
                                  cohesion . . . . . . . . . . . . . . . . 729
           Jawdat Al-Bassam and   
                  Yujia Cui and   
        Dieter Klopfenstein and   
       Bridget O. Carragher and   
             Ronald D. Vale and   
             Ronald A. Milligan   Distinct conformations of the kinesin
                                  Unc104 neck regulate a monomer to dimer
                                  motor transition . . . . . . . . . . . . 743
             Pradipta Ghosh and   
            Janice Griffith and   
              Hans J. Geuze and   
                Stuart Kornfeld   Mammalian GGAs act together to sort
                                  mannose $6$-phosphate receptors  . . . . 755
       Céline Jousse and   
          Seiichi Oyadomari and   
               Isabel Novoa and   
                  Phoebe Lu and   
               Yuhong Zhang and   
         Heather P. Harding and   
                      David Ron   Inhibition of a constitutive translation
                                  initiation factor 2$ \alpha $
                                  phosphatase, CReP, promotes survival of
                                  stressed cells . . . . . . . . . . . . . 767
             Luigia Atorino and   
            Laura Silvestri and   
               Mirko Koppen and   
              Laura Cassina and   
            Andrea Ballabio and   
            Roberto Marconi and   
              Thomas Langer and   
                 Giorgio Casari   Loss of m--AAA protease in mitochondria
                                  causes complex I deficiency and
                                  increased sensitivity to oxidative
                                  stress in hereditary spastic paraplegia  777
         Patrick Ryan Potts and   
               Shweta Singh and   
               Malia Knezek and   
          Craig B. Thompson and   
              Mohanish Deshmukh   Critical function of endogenous XIAP in
                                  regulating caspase activation during
                                  sympathetic neuronal apoptosis . . . . . 789
           Wilfried Rossoll and   
           Sibylle Jablonka and   
            Catia Andreassi and   
   Ann-Kathrin Kröning and   
              Kathrin Karle and   
            Umrao R. Monani and   
               Michael Sendtner   Smn, the spinal muscular
                                  atrophy--determining gene product,
                                  modulates axon growth and localization
                                  of $ \beta $-actin mRNA in growth cones
                                  of motoneurons . . . . . . . . . . . . . 801
          Kazuhito Tomizawa and   
             Satoshi Sunada and   
                 Yun-Fei Lu and   
                Yoshiya Oda and   
            Masahiro Kinuta and   
             Toshio Ohshima and   
                 Taro Saito and   
                Fan-Yan Wei and   
        Masayuki Matsushita and   
              Sheng-Tian Li and   
             Kimiko Tsutsui and   
         Shin-ichi Hisanaga and   
        Katsuhiko Mikoshiba and   
                Kohji Takei and   
                  Hideki Matsui   Cophosphorylation of amphiphysin I and
                                  dynamin I by Cdk5 regulates
                                  clathrin-mediated endocytosis of
                                  synaptic vesicles  . . . . . . . . . . . 813
         Masakiyo Sakaguchi and   
          Masahiro Miyazaki and   
            Mikiro Takaishi and   
        Yoshihiko Sakaguchi and   
              Eiichi Makino and   
           Noriyuki Kataoka and   
            Hidenori Yamada and   
            Masayoshi Namba and   
                     Nam-ho Huh   S100C\slash A11 is a key mediator of
                                  Ca$^{2+}$-induced growth inhibition of
                                  human epidermal keratinocytes  . . . . . 825
           Santina Bruzzone and   
             Svenja Kunerth and   
               Elena Zocchi and   
           Antonio De Flora and   
                Andreas H. Guse   Spatio-temporal propagation of Ca$^{2+}$
                                  signals by cyclic ADP-ribose in 3T3
                                  cells stimulated via purinergic P2Y
                                  receptors  . . . . . . . . . . . . . . . 837
   Maralice Conacci-Sorrell and   
               Inbal Simcha and   
          Tamar Ben-Yedidia and   
             Janna Blechman and   
            Pierre Savagner and   
                 Avri Ben-Ze'ev   Autoregulation of E-cadherin expression
                                  by cadherin--cadherin interactions . . . 847
             Ayse G. Kayali and   
             Kurt Van Gunst and   
           Iain L. Campbell and   
         Aleksandr Stotland and   
             Marcie Kritzik and   
                 Guoxun Liu and   
Malin Flodström-Tullberg and   
             You-Qing Zhang and   
                Nora Sarvetnick   The stromal cell--derived factor-1$
                                  \alpha $/CXCR4 ligand--receptor axis is
                                  critical for progenitor survival and
                                  migration in the pancreas  . . . . . . . 859
             Sven Christian and   
                  Jan Pilch and   
           Maria E. Akerman and   
               Kimmo Porkka and   
            Pirjo Laakkonen and   
                Erkki Ruoslahti   Nucleolin expressed at the cell surface
                                  is a marker of endothelial cells in
                                  angiogenic blood vessels . . . . . . . . 871
       Dmitry E. Shvartsman and   
             Mariana Kotler and   
              Renee D. Tall and   
            Michael G. Roth and   
                  Yoav I. Henis   Differently anchored influenza
                                  hemagglutinin mutants display distinct
                                  interaction dynamics with mutual rafts   879
                Zu-Lin Chen and   
              Sidney Strickland   Laminin $ \gamma $1 is critical for
                                  Schwann cell differentiation, axon
                                  myelination, and regeneration in the
                                  peripheral nerve . . . . . . . . . . . . 889
                 Karin List and   
                Roman Szabo and   
            Philip W. Wertz and   
                Julie Segre and   
  Christian C. Haudenschild and   
               Soo-Youl Kim and   
                Thomas H. Bugge   Loss of proteolytically processed
                                  filaggrin caused by epidermal deletion
                                  of Matriptase/MT-SP1 . . . . . . . . . . 901

Journal of Cell Biology
Volume 163, Number 5, December, 2003

              Nicole LeBrasseur   Fewer phosphates but fatter axons  . . . ??
              Nicole LeBrasseur   The APC--tumor connection  . . . . . . . ??
              Nicole LeBrasseur   Neurons die one way or another . . . . . ??
              Nicole LeBrasseur   Fusion fuels killing . . . . . . . . . . ??
              Nicole LeBrasseur   Tearing down actin . . . . . . . . . . . ??
               William A. Wells   Managing tension . . . . . . . . . . . . ??
               William A. Wells   Civil war in the immune system . . . . . ??
               William A. Wells   Catenin keeps vesicles close . . . . . . ??
               William A. Wells   S is for sticky  . . . . . . . . . . . . ??
               William A. Wells   Worms delay in deep sleep  . . . . . . . ??
                 Ebru Erbay and   
               In-Hyun Park and   
              Paul D. Nuzzi and   
  Christopher J. Schoenherr and   
                       Jie Chen   IGF-II transcription in skeletal
                                  myogenesis is controlled by mTOR and
                                  nutrients  . . . . . . . . . . . . . . . 931
                Hong-Guo Yu and   
            Douglas E. Koshland   Meiotic condensin is required for proper
                                  chromosome compaction, SC assembly, and
                                  resolution of recombination-dependent
                                  chromosome linkages  . . . . . . . . . . 937
           Rebecca A. Green and   
              Kenneth B. Kaplan   Chromosome instability in colorectal
                                  tumor cells is associated with defects
                                  in microtubule plus-end attachments
                                  caused by a dominant mutation in APC . . 949
          Carolyn A. Moores and   
      Mohammad Hekmat-Nejad and   
             Roman Sakowicz and   
             Ronald A. Milligan   Regulation of KinI kinesin ATPase
                                  activity by binding to the microtubule
                                  lattice  . . . . . . . . . . . . . . . . 963
              Chao-Wen Wang and   
           Per E. Stromhaug and   
          Emily J. Kauffman and   
            Lois S. Weisman and   
             Daniel J. Klionsky   Yeast homotypic vacuole fusion requires
                                  the Ccz1--Mon1 complex during the
                                  tethering/docking stage  . . . . . . . . 973
                 Li-Ying Yu and   
              Eija Jokitalo and   
                 Yun-Fu Sun and   
             Patrick Mehlen and   
               Dan Lindholm and   
                Mart Saarma and   
              Urmas Arumäe   GDNF-deprived sympathetic neurons die
                                  via a novel nonmitochondrial pathway . . 987
          H. Nicholas Marsh and   
      Catherine I. Dubreuil and   
              Celia Quevedo and   
                   Anna Lee and   
               Marta Majdan and   
           Gregory S. Walsh and   
           Sharon Hausdorff and   
            Farid Arab Said and   
                Olga Zoueva and   
             Maya Kozlowski and   
      Katherine Siminovitch and   
           Benjamin G. Neel and   
            Freda D. Miller and   
                David R. Kaplan   SHP-1 negatively regulates neuronal
                                  survival by functioning as a TrkA
                                  phosphatase  . . . . . . . . . . . . . . 999
          Michael L. Garcia and   
      Christian S. Lobsiger and   
             Sameer B. Shah and   
            Tom J. Deerinck and   
                  John Crum and   
               Darren Young and   
        Christopher M. Ward and   
         Thomas O. Crawford and   
             Takahiro Gotow and   
             Yasuo Uchiyama and   
           Mark H. Ellisman and   
           Nigel A. Calcutt and   
               Don W. Cleveland   NF-M is an essential target for the
                                  myelin-directed ``outside-in'' signaling
                                  cascade that mediates radial axonal
                                  growth . . . . . . . . . . . . . . . . . 1011
                Mala V. Rao and   
            Jabbar Campbell and   
                Aidong Yuan and   
                 Asok Kumar and   
             Takahiro Gotow and   
             Yasuo Uchiyama and   
                 Ralph A. Nixon   The neurofilament middle molecular mass
                                  subunit carboxyl-terminal tail domains
                                  is essential for the radial growth and
                                  cytoskeletal architecture of axons but
                                  not for regulating neurofilament
                                  transport rate . . . . . . . . . . . . . 1021
      Kimberly L. Fritz-Six and   
             Patrick R. Cox and   
          Robert S. Fischer and   
                  Bisong Xu and   
          Carol C. Gregorio and   
             Huda Y. Zoghbi and   
                Velia M. Fowler   Aberrant myofibril assembly in
                                  tropomodulin1 null mice leads to aborted
                                  heart development and embryonic
                                  lethality  . . . . . . . . . . . . . . . 1033
         Patricia A. Loomis and   
                 Lili Zheng and   
 Gabriella Sekerková and   
      Benjarat Changyaleket and   
            Enrico Mugnaini and   
               James R. Bartles   Espin cross-links cause the elongation
                                  of microvillus-type parallel actin
                                  bundles in vivo  . . . . . . . . . . . . 1045
           Vitold E. Galkin and   
              Albina Orlova and   
       Margaret S. VanLoock and   
         Alexander Shvetsov and   
               Emil Reisler and   
              Edward H. Egelman   ADF\slash cofilin use an intrinsic mode
                                  of F-actin instability to disrupt actin
                                  filaments  . . . . . . . . . . . . . . . 1057
          Mitsunobu Hoshino and   
                  Shun Nakamura   Small GTPase Rin induces neurite
                                  outgrowth through Rac/Cdc42 and
                                  calmodulin in PC12 cells . . . . . . . . 1067
         Kazunari Nishimura and   
            Fumie Yoshihara and   
              Takuro Tojima and   
              Noriko Ooashi and   
               Woohyun Yoon and   
        Katsuhiko Mikoshiba and   
               Vann Bennett and   
             Hiroyuki Kamiguchi   L1-dependent neuritogenesis involves
                                  ankyrin$_B$ that mediates L1-CAM
                                  coupling with retrograde actin flow  . . 1077
           Melissa M. Rolls and   
            Roger Albertson and   
              Hsin-Pei Shih and   
               Cheng-Yu Lee and   
                   Chris Q. Doe   Drosophila aPKC regulates cell polarity
                                  and cell proliferation in neuroblasts
                                  and epithelia  . . . . . . . . . . . . . 1089
          Erik-Jan Kamsteeg and   
           Daniel G. Bichet and   
        Irene B. M. Konings and   
               Hubert Nivet and   
          Michelle Lonergan and   
Marie-Françoise Arthus and   
            Carel H. van Os and   
               Peter M. T. Deen   Reversed polarized delivery of an
                                  aquaporin-2 mutant causes dominant
                                  nephrogenic diabetes insipidus . . . . . 1099
             Magali Prigent and   
             Thierry Dubois and   
        Graça Raposo and   
     Valérie Derrien and   
            Dani\`ele Tenza and   
        Carine Rossé and   
            Jacques Camonis and   
              Philippe Chavrier   ARF6 controls post-endocytic recycling
                                  through its downstream exocyst complex
                                  effector . . . . . . . . . . . . . . . . 1111
      Lorraine D. Hernandez and   
               Marc Pypaert and   
         Richard A. Flavell and   
          Jorge E. Galán   A Salmonella protein causes macrophage
                                  cell death by inducing autophagy . . . . 1123
Bénédicte Chazaud and   
             Corinne Sonnet and   
              Peggy Lafuste and   
           Guillaume Bassez and   
Anne-Cécile Rimaniol and   
     Françoise Poron and   
François-Jérôme Authier and   
         Patrick A. Dreyfus and   
             Romain K. Gherardi   Satellite cells attract monocytes and
                                  use macrophages as a support to escape
                                  apoptosis and enhance muscle growth  . . 1133
          Boris Tchernychev and   
                Bruce Furie and   
               Barbara C. Furie   Peritoneal macrophages express both
                                  P-selectin and PSGL-1  . . . . . . . . . 1145
          Elsa-Noah N'Diaye and   
                  Eric J. Brown   The ubiquitin-related protein PLIC-1
                                  regulates heterotrimeric G protein
                                  function through association with G$
                                  \beta \gamma $ . . . . . . . . . . . . . 1157
       Christopher S. Stipp and   
     Tatiana V. Kolesnikova and   
               Martin E. Hemler   EWI-2 regulates $ \alpha $3$ \beta $1
                                  integrin-dependent cell functions on
                                  laminin-5  . . . . . . . . . . . . . . . 1167

Journal of Cell Biology
Volume 163, Number 6, December, 2003

                   Alan W. Dove   Math models morphogenesis and mitosis    ??
                   Alan W. Dove   Cup puts a lid and a handle on mRNA  . . ??
                   Alan W. Dove   Cells need backward motor to move
                                  forward  . . . . . . . . . . . . . . . . ??
                   Alan W. Dove   Death and the shrinking nucleus  . . . . ??
                   Alan W. Dove   Neural progenitors find VEGF attractive  ??
              Nicole LeBrasseur   Transcribed in synchronicity . . . . . . ??
              Nicole LeBrasseur   Auxin auxin everywhere . . . . . . . . . ??
              Nicole LeBrasseur   Eggs never forget  . . . . . . . . . . . ??
              Nicole LeBrasseur   Calcium makes a fast getaway . . . . . . ??
              Nicole LeBrasseur   Knocked down a Notch with age  . . . . . ??
                     Paul Lasko   Cup-ling oskar RNA localization and
                                  translational control  . . . . . . . . . 1189
            Wolfgang Wagner and   
                 John A. Hammer   Myosin V and the endoplasmic reticulum   1193
           James E. Wilhelm and   
            Meredith Hilton and   
               Quinlan Amos and   
              William J. Henzel   Cup is an eIF4E binding protein required
                                  for both the translational repression of
                                  oskar and the recruitment of Barentsz    1197
          Denis L. Dujardin and   
           Lora E. Barnhart and   
       Stephanie A. Stehman and   
             Edgar R. Gomes and   
         Gregg G. Gundersen and   
              Richard B. Vallee   A role for cytoplasmic dynein and LIS1
                                  in directed cell movement  . . . . . . . 1205
               Leora Gollan and   
            Daniela Salomon and   
            James L. Salzer and   
                    Elior Peles   Caspr regulates the processing of
                                  contactin and inhibits its binding to
                                  neurofascin  . . . . . . . . . . . . . . 1213
              Koei Shinzawa and   
            Yoshihide Tsujimoto   PLA$_2$ activity is required for nuclear
                                  shrinkage in caspase-independent cell
                                  death  . . . . . . . . . . . . . . . . . 1219
          Brian J. Tunquist and   
           Patrick A. Eyers and   
                Lin G. Chen and   
         Andrea L. Lewellyn and   
                James L. Maller   Spindle checkpoint proteins Mad1 and
                                  Mad2 are required for cytostatic
                                  factor--mediated metaphase arrest  . . . 1231
           Andrea Ciliberto and   
                 Bela Novak and   
                  John J. Tyson   Mathematical model of the morphogenesis
                                  checkpoint in budding yeast  . . . . . . 1243
              Paula Estrada and   
                  Jiwon Kim and   
               Jeff Coleman and   
                 Lee Walker and   
                 Brian Dunn and   
             Peter Takizawa and   
               Peter Novick and   
             Susan Ferro-Novick   Myo4p and She3p are required for
                                  cortical ER inheritance in
                                  \bionameSaccharomyces cerevisiae . . . . 1255
    Elizabeth E. Grevengoed and   
              Donald T. Fox and   
                Julie Gates and   
                    Mark Peifer   Balancing different types of actin
                                  polymerization at distinct sites . . . . 1267
               Katy Janvier and   
                 Yukio Kato and   
               Markus Boehm and   
             Jeremy R. Rose and   
     José A. Martina and   
              Bong-Yoon Kim and   
    Sundararajan Venkatesan and   
             Juan S. Bonifacino   Recognition of dileucine-based sorting
                                  signals from HIV-1 Nef and LIMP--II by
                                  the AP-1 $ \gamma $--$ \sigma $1 and
                                  AP-3 $ \delta $--$ \sigma $3
                                  hemicomplexes  . . . . . . . . . . . . . 1281
                Ali Nawshad and   
               Elizabeth D. Hay   TGF$ \beta_3 $ signaling activates
                                  transcription of the LEF1 gene to induce
                                  epithelial mesenchymal transformation
                                  during mouse palate development  . . . . 1291
             Tetsuro Watabe and   
            Ayako Nishihara and   
             Koichi Mishima and   
              Jun Yamashita and   
            Kiyoshi Shimizu and   
             Keiji Miyazawa and   
        Shin-Ichi Nishikawa and   
                 Kohei Miyazono   TGF-$ \beta $ receptor kinase inhibitor
                                  enhances growth and integrity of
                                  embryonic stem cell--derived endothelial
                                  cells  . . . . . . . . . . . . . . . . . 1303
            Mark Henkemeyer and   
              Olga S. Itkis and   
               Michelle Ngo and   
          Peter W. Hickmott and   
                Iryna M. Ethell   Multiple EphB receptor tyrosine kinases
                                  shape dendritic spines in the
                                  hippocampus  . . . . . . . . . . . . . . 1313
               Sabine Uhles and   
                 Tilo Moede and   
           Barbara Leibiger and   
          Per-Olof Berggren and   
               Ingo B. Leibiger   Isoform-specific insulin receptor
                                  signaling involves different plasma
                                  membrane domains . . . . . . . . . . . . 1327
                   Kun Ling and   
          Renee L. Doughman and   
             Vidhya V. Iyer and   
           Ari J. Firestone and   
          Shawn F. Bairstow and   
            Deane F. Mosher and   
        Michael D. Schaller and   
            Richard A. Anderson   Tyrosine phosphorylation of type I$
                                  \gamma $ phosphatidylinositol phosphate
                                  kinase by Src regulates an
                                  integrin--talin switch . . . . . . . . . 1339
     Nibedita Chattopadhyay and   
                 Zemin Wang and   
           Leonie K. Ashman and   
     Susann M. Brady-Kalnay and   
            Jordan A. Kreidberg   $ \alpha $3$ \beta $1 integrin--CD151, a
                                  component of the cadherin--catenin
                                  complex, regulates PTP$ \mu $ expression
                                  and cell--cell adhesion  . . . . . . . . 1351
      Marko Hyytiäinen and   
                Jorma Keski-Oja   Latent TGF-$ \beta $ binding protein
                                  LTBP-2 decreases fibroblast adhesion to
                                  fibronectin  . . . . . . . . . . . . . . 1363
            Huanxiang Zhang and   
            Laszlo Vutskits and   
          Michael S. Pepper and   
                 Jozsef Z. Kiss   VEGF is a chemoattractant for
                                  FGF-2--stimulated neural progenitors . . 1375
             Hendra Setiadi and   
               Rodger P. McEver   Signal-dependent distribution of cell
                                  surface P-selectin in clathrin-coated
                                  pits affects leukocyte rolling under
                                  flow . . . . . . . . . . . . . . . . . . 1385
             Nastaran Zahir and   
        Johnathon N. Lakins and   
               Alan Russell and   
                 WenYu Ming and   
       Chandrima Chatterjee and   
      Gabriela I. Rozenberg and   
       M. Peter Marinkovich and   
              Valerie M. Weaver   Autocrine laminin-5 ligates $ \alpha $6$
                                  \beta $4 integrin and activates RAC and
                                  NF$ \kappa $B to mediate
                                  anchorage-independent survival of
                                  mammary tumors . . . . . . . . . . . . . 1397


Journal of Cell Biology
Volume 164, Number 1, January, 2004

              Nicole LeBrasseur   Heart-shaped clones  . . . . . . . . . . ??
              Nicole LeBrasseur   Membrane fusion SNAREs an inhibitor  . . ??
              Nicole LeBrasseur   Awakening heterochromatin  . . . . . . . ??
              Nicole LeBrasseur   Malaria protease takes an indirect route ??
              Nicole LeBrasseur   Calcium pumps need a chaperone . . . . . ??
               William A. Wells   Protein translocation pulls the plug . . ??
               William A. Wells   A circular uncoating mechanism . . . . . ??
               William A. Wells   Giving neural precursors the finger  . . ??
               William A. Wells   Formin' adherens junctions . . . . . . . ??
               William A. Wells   Oxidation makes a germline . . . . . . . ??
               Mike Rossner and   
                  Rob O'Donnell   The JCB will let your data shine in RGB  11
            Anton Sandqvist and   
                   Lea Sistonen   Nuclear stress granules  . . . . . . . . 15
                 Ian Gentle and   
             Kipros Gabriel and   
                Peter Beech and   
                Ross Waller and   
                 Trevor Lithgow   The Omp85 family of proteins is
                                  essential for outer membrane biogenesis
                                  in mitochondria and bacteria . . . . . . 19
             Caroline Jolly and   
             Alexandra Metz and   
  Jérôme Govin and   
              Marc Vigneron and   
            Bryan M. Turner and   
             Saadi Khochbin and   
                 Claire Vourc'h   Stress-induced transcription of
                                  satellite III repeats  . . . . . . . . . 25
                     Yun Li and   
               Patricia Camacho   Ca$^{2+}$-dependent redox modulation of
                                  SERCA 2b by ERp57  . . . . . . . . . . . 35
             Michael Klemba and   
               Wandy Beatty and   
               Ilya Gluzman and   
             Daniel E. Goldberg   Trafficking of plasmepsin II to the food
                                  vacuole of the malaria parasite
                                  Plasmodium falciparum  . . . . . . . . . 47
             Jacob M. Jones and   
           James C. Morrell and   
               Stephen J. Gould   PEX19 is a predominantly cytosolic
                                  chaperone and import receptor for class
                                  1 peroxisomal membrane proteins  . . . . 57
         Anne G. Ostermeyer and   
         Lynne T. Ramcharan and   
               Youchun Zeng and   
          Douglas M. Lublin and   
               Deborah A. Brown   Role of the hydrophobic domain in
                                  targeting caveolin-1 to lipid droplets   69
              Oleg Varlamov and   
              Allen Volchuk and   
             Vahid Rahimian and   
           Claudia A. Doege and   
            Fabienne Paumet and   
             William S. Eng and   
               Nancy Arango and   
          Francesco Parlati and   
         Mariella Ravazzola and   
                 Lelio Orci and   
     Thomas H. Söllner and   
               James E. Rothman   i-SNAREs . . . . . . . . . . . . . . . . 79
             Clare L. Scott and   
             Martin Schuler and   
         Vanessa S. Marsden and   
                  Alex Egle and   
            Marc Pellegrini and   
              Dobrila Nesic and   
           Steve Gerondakis and   
            Stephen L. Nutt and   
           Douglas R. Green and   
               Andreas Strasser   Apaf-1 and caspase-9 do not act as tumor
                                  suppressors in myc-induced
                                  lymphomagenesis or mouse embryo
                                  fibroblast transformation  . . . . . . . 89
      Sigol\`ene M. Meilhac and   
                Milan Esner and   
           Michel Kerszberg and   
              Julie E. Moss and   
         Margaret E. Buckingham   Oriented clonal cell growth in the
                                  developing mouse myocardium underlies
                                  cardiac morphogenesis  . . . . . . . . . 97
                Jenny Hsieh and   
            James B. Aimone and   
            Brian K. Kaspar and   
            Tomoko Kuwabara and   
          Kinichi Nakashima and   
                   Fred H. Gage   IGF-I instructs multipotent adult neural
                                  progenitor cells to become
                                  oligodendrocytes . . . . . . . . . . . . 111
              Jiunn-Tay Lee and   
                     Jan Xu and   
                Jin-Moo Lee and   
                   Grace Ku and   
                Xianlin Han and   
                Ding-I Yang and   
                Shawei Chen and   
                   Chung Y. Hsu   Amyloid-$ \beta $ peptide induces
                                  oligodendrocyte death by activating the
                                  neutral sphingomyelinase--ceramide
                                  pathway  . . . . . . . . . . . . . . . . 123
          Christelle Benaud and   
        Beno\^\it J. Gentil and   
              Nicole Assard and   
              Magalie Court and   
               Jerome Garin and   
          Christian Delphin and   
                Jacques Baudier   AHNAK interaction with the annexin
                                  2/S100A10 complex regulates cell
                                  membrane cytoarchitecture  . . . . . . . 133
           Alessandra Cambi and   
             Frank de Lange and   
  Noortje M. van Maarseveen and   
            Monique Nijhuis and   
                Ben Joosten and   
     Erik M. H. P. van Dijk and   
   Bärbel I. de Bakker and   
         Jack A. M. Fransen and   
   Petra H. M. Bovee-Geurts and   
       Frank N. van Leeuwen and   
          Niek F. Van Hulst and   
                 Carl G. Figdor   Microdomains of the C-type lectin
                                  DC--SIGN are portals for virus entry
                                  into dendritic cells . . . . . . . . . . 145

Journal of Cell Biology
Volume 164, Number 2, January, 2004

                   Alan W. Dove   More than one way to skin a phagosome    ??
                   Alan W. Dove   How to terminate a shmoo . . . . . . . . ??
                   Alan W. Dove   SNAREs drum up calcium . . . . . . . . . ??
                   Alan W. Dove   Conjunction of junctions goes beyond
                                  function . . . . . . . . . . . . . . . . ??
                   Alan W. Dove   How insulin signals globally and acts
                                  locally  . . . . . . . . . . . . . . . . ??
             Patricia Zambryski   Cell-to-cell transport of proteins and
                                  fluorescent tracers via plasmodesmata
                                  during plant development . . . . . . . . 165
             Hidekazu Iioka and   
                 Naoto Ueno and   
             Noriyuki Kinoshita   Essential role of MARCKS in cortical
                                  actin dynamics during gastrulation
                                  movements  . . . . . . . . . . . . . . . 169
          Walbert J. Bakker and   
Montserrat Blázquez-Domingo and   
              Andrea Kolbus and   
             Janey Besooyen and   
            Peter Steinlein and   
               Hartmut Beug and   
             Paul J. Coffer and   
         Bob Löwenberg and   
        Marieke von Lindern and   
             Thamar B. van Dijk   FoxO3a regulates erythroid
                                  differentiation and induces BTG1, an
                                  activator of protein arginine methyl
                                  transferase 1  . . . . . . . . . . . . . 175
           Rebecca M. Henry and   
              Adam D. Hoppe and   
               Nikhil Joshi and   
                Joel A. Swanson   The uniformity of phagosome maturation
                                  in macrophages . . . . . . . . . . . . . 185
             Alexey J. Merz and   
             William T. Wickner   Trans-SNARE interactions elicit
                                  Ca$^{2+}$ efflux from the yeast vacuole
                                  lumen  . . . . . . . . . . . . . . . . . 195
         Scott Bidlingmaier and   
                 Michael Snyder   Regulation of polarized growth
                                  initiation and termination cycles by the
                                  polarisome and Cdc42 regulators  . . . . 207
         Thomas Höfken and   
                 Elmar Schiebel   Novel regulation of mitotic exit by the
                                  Cdc42 effectors Gic1 and Gic2  . . . . . 219
           Catherine Lindon and   
                 Jonathon Pines   Ordered proteolysis in anaphase
                                  inactivates Plk1 to contribute to proper
                                  mitotic exit in human cells  . . . . . . 233
              Lorenza Ciani and   
               Olga Krylova and   
         Matthew J. Smalley and   
             Trevor C. Dale and   
            Patricia C. Salinas   A divergent canonical WNT-signaling
                                  pathway regulates microtubule dynamics   243
                Hongmin Qin and   
           Dennis R. Diener and   
              Stefan Geimer and   
            Douglas G. Cole and   
              Joel L. Rosenbaum   Intraflagellar transport (IFT) cargo . . 255
           Anasua B. Kusari and   
          Douglas M. Molina and   
              Walid Sabbagh and   
               Chang S. Lau and   
                   Lee Bardwell   A conserved protein interaction network
                                  involving the yeast MAP kinases Fus3 and
                                  Kss1 . . . . . . . . . . . . . . . . . . 267
             Makoto Kanzaki and   
                Silvia Mora and   
            Joseph B. Hwang and   
            Alan R. Saltiel and   
              Jeffrey E. Pessin   Atypical protein kinase C (PKC$ \zeta $
                                  /$ \lambda $) is a convergent downstream
                                  target of the insulin-stimulated
                                  phosphatidylinositol $3$-kinase and TC10
                                  signaling pathways . . . . . . . . . . . 279
                 Weibin Shi and   
                Chuanxi Sun and   
                     Bin He and   
             Wencheng Xiong and   
               Xingming Shi and   
                 Dachun Yao and   
                         Xu Cao   GADD34--PP1c recruited by Smad7
                                  dephosphorylates TGF$ \beta $ type I
                                  receptor . . . . . . . . . . . . . . . . 291
       Etsuko Takao-Rikitsu and   
             Sumiko Mochida and   
                 Eiji Inoue and   
      Maki Deguchi-Tawarada and   
                Marie Inoue and   
          Toshihisa Ohtsuka and   
                  Yoshimi Takai   Physical and functional interaction of
                                  the active zone proteins, CAST, RIM1,
                                  and Bassoon, in neurotransmitter release 301
             Victoria M. Wu and   
              Joost Schulte and   
          Alexander Hirschi and   
              Ulrich Tepass and   
                 Greg J. Beitel   Sinuous is a \bionameDrosophila claudin
                                  required for septate junction
                                  organization and epithelial tube size
                                  control  . . . . . . . . . . . . . . . . 313

Journal of Cell Biology
Volume 164, Number 3, February, 2004

                   Alan W. Dove   New structure found in plain sight . . . ??
                   Alan W. Dove   Krox-20 conducts the Schwann song  . . . ??
                   Alan W. Dove   Kinase cascades are binary to the bone   ??
                   Alan W. Dove   Switching mating types with one arm tied ??
                   Alan W. Dove   Actin organizer takes pathogens for a
                                  ride . . . . . . . . . . . . . . . . . . ??
                    Rabiya Tuma   A sensitive measure of repression  . . . ??
                    Rabiya Tuma   Repopulating glioma cell lines . . . . . ??
                    Rabiya Tuma   Sticking to PIP$_2$  . . . . . . . . . . ??
                    Rabiya Tuma   Parsing p53 activity . . . . . . . . . . ??
                    Rabiya Tuma   RNAi-mediated DNA silencing  . . . . . . ??
               William A. Wells   Man the nanoscopes . . . . . . . . . . . 337
             Benjamin P. Tu and   
           Jonathan S. Weissman   Oxidative protein folding in eukaryotes  341
                Michael Glotzer   Cleavage furrow positioning  . . . . . . 347
          Nick I. Markevich and   
                Jan B. Hoek and   
            Boris N. Kholodenko   Signaling switches and bistability
                                  arising from multisite phosphorylation
                                  in protein kinase cascades . . . . . . . 353
           Debra A. Bressan and   
              Julio Vazquez and   
                 James E. Haber   Mating type-dependent constraints on the
                                  mobility of the left arm of yeast
                                  chromosome III . . . . . . . . . . . . . 361
         Yoshikazu Imanishi and   
          Matthew L. Batten and   
            David W. Piston and   
             Wolfgang Baehr and   
           Krzysztof Palczewski   Noninvasive two-photon imaging reveals
                                  retinyl ester storage structures in the
                                  eye  . . . . . . . . . . . . . . . . . . 373
         David B. Parkinson and   
           Ambily Bhaskaran and   
              Anna Droggiti and   
            Sarah Dickinson and   
         Maurizio D'Antonio and   
               Rhona Mirsky and   
             Kristjan R. Jessen   Krox-20 inhibits Jun--NH$_2$-terminal
                                  kinase/c--Jun to control Schwann cell
                                  proliferation and death  . . . . . . . . 385
            Hiroshi Akazawa and   
               Sumiyo Kudoh and   
            Naoki Mochizuki and   
           Noboru Takekoshi and   
            Hiroyuki Takano and   
               Toshio Nagai and   
                   Issei Komuro   A novel LIM protein Cal promotes cardiac
                                  differentiation by association with
                                  CSX/NKX2-5 . . . . . . . . . . . . . . . 395
      Kenneth G. Campellone and   
            Susannah Rankin and   
                Tony Pawson and   
          Marc W. Kirschner and   
           Donald J. Tipper and   
                  John M. Leong   Clustering of Nck by a $ 12$-residue Tir
                                  phosphopeptide is sufficient to trigger
                                  localized actin assembly . . . . . . . . 407
           Andrew C. Zelhof and   
                Robert W. Hardy   WASp is required for the correct
                                  temporal morphogenesis of rhabdomere
                                  microvilli . . . . . . . . . . . . . . . 417
               Go Totsukawa and   
                     Yue Wu and   
            Yasuharu Sasaki and   
        David J. Hartshorne and   
         Yoshihiko Yamakita and   
          Shigeko Yamashiro and   
                Fumio Matsumura   Distinct roles of MLCK and ROCK in the
                                  regulation of membrane protrusions and
                                  focal adhesion dynamics during cell
                                  migration of fibroblasts . . . . . . . . 427
            Roberta Palumbo and   
        Maurilio Sampaolesi and   
       Francesco De Marchis and   
         Rossana Tonlorenzi and   
            Sara Colombetti and   
               Anna Mondino and   
               Giulio Cossu and   
               Marco E. Bianchi   Extracellular HMGB1, a signal of tissue
                                  damage, induces mesoangioblast migration
                                  and proliferation  . . . . . . . . . . . 441
                  Lijun Xia and   
               Tongzhong Ju and   
         Andrew Westmuckett and   
                 Guangyu An and   
        Lacramioara Ivanciu and   
        J. Michael McDaniel and   
                Florea Lupu and   
        Richard D. Cummings and   
               Rodger P. McEver   Defective angiogenesis and fatal
                                  embryonic hemorrhage in mice lacking
                                  core $1$--derived O-glycans  . . . . . . 451
           Trever G. Bivona and   
            Heidi H. Wiener and   
              Ian M. Ahearn and   
            Joseph Silletti and   
                 Vi K. Chiu and   
                Mark R. Philips   Rap1 up-regulation and activation on
                                  plasma membrane regulates T cell
                                  adhesion . . . . . . . . . . . . . . . . 461

Journal of Cell Biology
Volume 164, Number 4, February, 2004

                   Alan W. Dove   How meals become bones . . . . . . . . . ??
                   Alan W. Dove   A primordial mover for sphingolipids . . ??
                   Alan W. Dove   Yeast dies for a noble cause . . . . . . ??
                   Alan W. Dove   Boning up on JunB  . . . . . . . . . . . ??
                   Alan W. Dove   Apoptotic mitochondria blow a fuse . . . ??
              Nicole LeBrasseur   Protein splicing for immunity  . . . . . ??
              Nicole LeBrasseur   Breathe, then breed  . . . . . . . . . . ??
              Nicole LeBrasseur   Inflexibility in motion  . . . . . . . . ??
              Nicole LeBrasseur   Winding and unwinding ATP synthase . . . ??
              Nicole LeBrasseur   Nanofibers have the right stuff  . . . . ??
           William A. Wells and   
              Nicole LeBrasseur   Cells on Parade  . . . . . . . . . . . . 480
                Jiangtao Yu and   
          Shawna L. Fleming and   
             Byron Williams and   
          Erika V. Williams and   
                  ZeXiao Li and   
             Patrizia Somma and   
            Conly L. Rieder and   
            Michael L. Goldberg   Greatwall kinase . . . . . . . . . . . . 487
          Mariusz Karbowski and   
             Damien Arnoult and   
              Hsiuchen Chen and   
              David C. Chan and   
           Carolyn L. Smith and   
               Richard J. Youle   Quantitation of mitochondrial dynamics
                                  by photolabeling of individual
                                  organelles shows that mitochondrial
                                  fusion is blocked during the Bax
                                  activation phase of apoptosis  . . . . . 493
                 Eva Herker and   
           Helmut Jungwirth and   
       Katharina A. Lehmann and   
           Corinna Maldener and   
      Kai-Uwe Fröhlich and   
              Silke Wissing and   
       Sabrina Büttner and   
                Markus Fehr and   
            Stephan Sigrist and   
                    Frank Madeo   Chronological aging leads to apoptosis
                                  in yeast . . . . . . . . . . . . . . . . 501
             Romain Dacquin and   
            Rachel A. Davey and   
          Catherine Laplace and   
     Régis Levasseur and   
           Howard A. Morris and   
         Steven R. Goldring and   
        Samuel Gebre-Medhin and   
          Deborah L. Galson and   
           Jeffrey D. Zajac and   
         Gérard Karsenty   Amylin inhibits bone resorption while
                                  the calcitonin receptor controls bone
                                  formation in vivo  . . . . . . . . . . . 509
                Jayson Wang and   
               Carol Shiels and   
              Peter Sasieni and   
                 Pei Jun Wu and   
            Suhail A. Islam and   
           Paul S. Freemont and   
                   Denise Sheer   Promyelocytic leukemia nuclear bodies
                                  associate with transcriptionally active
                                  genomic regions  . . . . . . . . . . . . 515
         Jonathan H. Zippin and   
             Jeanne Farrell and   
                David Huron and   
       Margarita Kamenetsky and   
            Kenneth C. Hess and   
         Donald A. Fischman and   
             Lonny R. Levin and   
                    Jochen Buck   Bicarbonate-responsive ``soluble''
                                  adenylyl cyclase defines a nuclear cAMP
                                  microdomain  . . . . . . . . . . . . . . 527
           Emily S. Gillett and   
     Christopher W. Espelin and   
                Peter K. Sorger   Spindle checkpoint proteins and
                                  chromosome--microtubule attachment in
                                  budding yeast  . . . . . . . . . . . . . 535
      Krishnamurthy Malathi and   
             Katsumi Higaki and   
     Arthur H. Tinkelenberg and   
           Dina A. Balderes and   
     Dorca Almanzar-Paramio and   
             Lisa J. Wilcox and   
                Naz Erdeniz and   
            Francis Redican and   
        Mahajabeen Padamsee and   
                   Ying Liu and   
                Sohail Khan and   
        Frederick Alcantara and   
          Eugene D. Carstea and   
             Jill A. Morris and   
             Stephen L. Sturley   Mutagenesis of the putative
                                  sterol-sensing domain of yeast Niemann
                                  Pick C--related protein reveals a
                                  primordial role in subcellular
                                  sphingolipid distribution  . . . . . . . 547
                  Yun Liang and   
                     Wei Yu and   
                     Yan Li and   
                Zhenye Yang and   
                 Xiumin Yan and   
            Qiongping Huang and   
                   Xueliang Zhu   Nudel functions in membrane traffic
                                  mainly through association with Lis1 and
                                  cytoplasmic dynein . . . . . . . . . . . 557
              Kyoungtae Kim and   
           Atsuko Yamashita and   
             Martin A. Wear and   
      Yuichiro Maéda and   
                 John A. Cooper   Capping protein binding to actin in
                                  yeast  . . . . . . . . . . . . . . . . . 567
           Raymond Wightman and   
               Steven Bates and   
       Pat Amornrrattanapan and   
                  Peter Sudbery   In Candida albicans, the Nim1 kinases
                                  Gin4 and Hsl1 negatively regulate
                                  pseudohypha formation and Gin4 also
                                  controls septin organization . . . . . . 581
                  Cai Huang and   
      Christoph H. Borchers and   
        Michael D. Schaller and   
                   Ken Jacobson   Phosphorylation of paxillin by p38MAPK
                                  is involved in the neurite extension of
                                  PC-12 cells  . . . . . . . . . . . . . . 593
                   Hong Liu and   
           Derek C. Radisky and   
                   Fei Wang and   
                Mina J. Bissell   Polarity and proliferation are
                                  controlled by distinct signaling
                                  pathways downstream of PI3-kinase in
                                  breast epithelial tumor cells  . . . . . 603
               Lukas Kenner and   
            Astrid Hoebertz and   
               F. Timo Beil and   
                 Niamh Keon and   
            Florian Karreth and   
               Robert Eferl and   
             Harald Scheuch and   
         Agnieszka Szremska and   
             Michael Amling and   
     Marina Schorpp-Kistner and   
                Peter Angel and   
                Erwin F. Wagner   Mice lacking JunB are osteopenic due to
                                  cell-autonomous osteoblast and
                                  osteoclast defects . . . . . . . . . . . 613
             Michael Klemba and   
               Wandy Beatty and   
               Ilya Gluzman and   
             Daniel E. Goldberg   Correction . . . . . . . . . . . . . . . 625

Journal of Cell Biology
Volume 164, Number 5, March, 2004

              Nicole LeBrasseur   Migration on rafts . . . . . . . . . . . ??
              Nicole LeBrasseur   Lumens laid out by PAR-1 . . . . . . . . ??
              Nicole LeBrasseur   The nucleus shuns MAPK . . . . . . . . . ??
              Nicole LeBrasseur   Muscle loves company . . . . . . . . . . ??
              Nicole LeBrasseur   Antigens make a pit stop . . . . . . . . ??
               William A. Wells   Backward waves move cells forward  . . . ??
               William A. Wells   Flipping the fusion switch . . . . . . . ??
               William A. Wells   Solo polarization  . . . . . . . . . . . ??
               William A. Wells   Pulling out gene silencers . . . . . . . ??
               William A. Wells   Die --- but not just yet . . . . . . . . ??
                 Thoru Pederson   Can telomerase be put in its place?  . . 637
      Vladimir I. Titorenko and   
         Richard A. Rachubinski   The peroxisome . . . . . . . . . . . . . 641
Beáta E. Jády and   
           Edouard Bertrand and   
              Tamás Kiss   Human telomerase RNA and box H/ACA
                                  scaRNAs share a common Cajal
                                  body--specific localization signal . . . 647
            Bruno T. Fievet and   
            Alexis Gautreau and   
              Christian Roy and   
       Laurence Del Maestro and   
               Paul Mangeat and   
             Daniel Louvard and   
                  Monique Arpin   Phosphoinositide binding and
                                  phosphorylation act sequentially in the
                                  activation mechanism of ezrin  . . . . . 653
  Sabine H. Wimmer-Kleikamp and   
             Peter W. Janes and   
             Anthony Squire and   
   Philippe I. H. Bastiaens and   
                Martin Lackmann   Recruitment of Eph receptors into
                                  signaling clusters does not require
                                  ephrin contact . . . . . . . . . . . . . 661
            Hugues Lelouard and   
            Vincent Ferrand and   
             Didier Marguet and   
                Jacek Bania and   
        Voahirana Camosseto and   
            Alexandre David and   
              Evelina Gatti and   
                Philippe Pierre   Dendritic cell aggresome-like induced
                                  structures are dedicated areas for
                                  ubiquitination and storage of newly
                                  synthesized defective proteins . . . . . 667
        Matthew J. Youngman and   
      Alyson E. Aiken Hobbs and   
           Shawn M. Burgess and   
      Maithreyan Srinivasan and   
               Robert E. Jensen   Mmm2p, a mitochondrial outer membrane
                                  protein required for yeast mitochondrial
                                  shape and maintenance of mtDNA nucleoids 677
         Elizabeth R. Smith and   
       Jennifer L. Smedberg and   
         Malgorzata E. Rula and   
                    Xiang-Xi Xu   Regulation of Ras--MAPK pathway
                                  mitogenic activity by restricting
                                  nuclear entry of activated MAPK in
                                  endoderm differentiation of embryonic
                                  carcinoma and stem cells . . . . . . . . 689
           Matthias Versele and   
                 Jeremy Thorner   Septin collar formation in budding yeast
                                  requires GTP binding and direct
                                  phosphorylation by the PAK, Cla4 . . . . 701
                David Cohen and   
       Patrick J. Brennwald and   
   Enrique Rodriguez-Boulan and   
                Anne Müsch   Mammalian PAR-1 determines epithelial
                                  lumen polarity by organizing the
                                  microtubule cytoskeleton . . . . . . . . 717
              Yasushi Izumi and   
                   Nao Ohta and   
          Asako Itoh-Furuya and   
               Naoyuki Fuse and   
                Fumio Matsuzaki   Differential functions of G protein and
                                  Baz--aPKC signaling pathways in
                                  \bionameDrosophila neuroblast asymmetric
                                  division . . . . . . . . . . . . . . . . 729
          Jacquelyn Gerhart and   
            Christine Neely and   
           Benjamin Stewart and   
           Jordanna Perlman and   
             David Beckmann and   
          Margaretha Wallon and   
              Karen Knudsen and   
         Mindy George-Weinstein   Epiblast cells that express MyoD recruit
                                  pluripotent cells to the skeletal muscle
                                  lineage  . . . . . . . . . . . . . . . . 739
              Patrick Smits and   
                   Peter Dy and   
              Srijeet Mitra and   
      Véronique Lefebvre   Sox5 and Sox6 are needed to develop and
                                  maintain source, columnar, and
                                  hypertrophic chondrocytes in the
                                  cartilage growth plate . . . . . . . . . 747
Concepción Gómez-Moutón and   
           Rosa Ana Lacalle and   
                Emilia Mira and   
Sonia Jiménez-Baranda and   
          Domingo F. Barber and   
             Ana C. Carrera and   
  Carlos Martínez-A. and   
            Santos Mañes   Dynamic redistribution of raft domains
                                  as an organizing platform for signaling
                                  during cell chemotaxis . . . . . . . . . 759
                 Umut Sahin and   
             Gisela Weskamp and   
             Kristine Kelly and   
             Hong-Ming Zhou and   
        Shigeki Higashiyama and   
            Jacques Peschon and   
            Dieter Hartmann and   
                Paul Saftig and   
                 Carl P. Blobel   Distinct roles for ADAM10 and ADAM17 in
                                  ectodomain shedding of six EGFR ligands  769

Journal of Cell Biology
Volume 164, Number 6, March, 2004

               Karen Birmingham   Cilia that sense . . . . . . . . . . . . ??
               Karen Birmingham   Bigger equals faster . . . . . . . . . . ??
               Karen Birmingham   Keratins make you regular  . . . . . . . ??
               Karen Birmingham   Stay dynamic to slow aging . . . . . . . ??
               Karen Birmingham   Binding to the basement  . . . . . . . . ??
              Nicole LeBrasseur   Endosomes are ready and APPL to signal   ??
              Nicole LeBrasseur   Feudal system in metabolic flux  . . . . ??
              Nicole LeBrasseur   Any which way but loose  . . . . . . . . ??
              Nicole LeBrasseur   A dynamite intercellular highway . . . . ??
              Nicole LeBrasseur   Teeny tiny rafts . . . . . . . . . . . . ??
           Nicole R. Murray and   
               Lee Jamieson and   
               Wangsheng Yu and   
                  Jie Zhang and   
    Yesim Gökmen-Polar and   
               Deborah Sier and   
         Panos Anastasiadis and   
             Zoran Gatalica and   
         E. Aubrey Thompson and   
                 Alan P. Fields   Protein kinase C$ \iota $ is required
                                  for Ras transformation and colon
                                  carcinogenesis in vivo . . . . . . . . . 797
        Campbell W. Gourlay and   
           Lindsay N. Carpp and   
               Paul Timpson and   
           Steven J. Winder and   
            Kathryn R. Ayscough   A role for the actin cytoskeleton in
                                  cell death and aging in yeast  . . . . . 803
               Carlo Iomini and   
               Karla Tejada and   
                  Wenjun Mo and   
            Heikki Vaananen and   
                 Gianni Piperno   Primary cilia of human endothelial cells
                                  disassemble under laminar shear stress   811
           Hayley A. Webber and   
              Louisa Howard and   
               Sharon E. Bickel   The cohesion protein ORD is required for
                                  homologue bias during meiotic
                                  recombination  . . . . . . . . . . . . . 819
             Miroslav Dundr and   
          Michael D. Hebert and   
         Tatiana S. Karpova and   
               David Stanek and   
                  Hongzi Xu and   
           Karl B. Shpargel and   
            U. Thomas Meier and   
        Karla M. Neugebauer and   
          A. Gregory Matera and   
                    Tom Misteli   In vivo kinetics of Cajal body
                                  components . . . . . . . . . . . . . . . 831
              Stefan Wagner and   
             Simion Chiosea and   
              Maria Ivshina and   
           Jeffrey A. Nickerson   In vitro FRAP reveals the ATP-dependent
                                  nuclear mobilization of the exon
                                  junction complex protein SRm160  . . . . 843
      James I. S. MacDonald and   
              Chris J. Kubu and   
                Susan O. Meakin   Nesca, a novel adapter, translocates to
                                  the nuclear envelope and regulates
                                  neurotrophin-induced neurite outgrowth   851
                    Yi Fang and   
           James C. Morrell and   
             Jacob M. Jones and   
               Stephen J. Gould   PEX3 functions as a PEX19 docking factor
                                  in the import of class I peroxisomal
                                  membrane proteins  . . . . . . . . . . . 863
      Dimitry N. Krementsov and   
       Elena B. Krementsova and   
             Kathleen M. Trybus   Myosin V . . . . . . . . . . . . . . . . 877
    Agnieszka K. Rzadzinska and   
          Mark E. Schneider and   
            Caroline Davies and   
           Gavin P. Riordan and   
                 Bechara Kachar   An actin molecular treadmill and myosins
                                  maintain stereocilia functional
                                  architecture and self-renewal  . . . . . 887
           Falak M. Helwani and   
              Eva M. Kovacs and   
         Andrew D. Paterson and   
                Suzie Verma and   
              Radiya G. Ali and   
            Alan S. Fanning and   
              Scott A. Weed and   
                   Alpha S. Yap   Cortactin is necessary for
                                  E-cadherin-mediated contact formation
                                  and actin reorganization . . . . . . . . 899
           Diana M. Toivola and   
             Selvi Krishnan and   
            Henry J. Binder and   
            Satish K. Singh and   
                 M. Bishr Omary   Keratins modulate colonocyte electrolyte
                                  transport via protein mistargeting . . . 911
                Manu Sharma and   
       Francesca Pampinella and   
               Csilla Nemes and   
         Mohamed Benharouga and   
                 Jeffrey So and   
                     Kai Du and   
            Kristi G. Bache and   
               Blake Papsin and   
               Noa Zerangue and   
            Harald Stenmark and   
              Gergely L. Lukacs   Misfolding diverts CFTR from recycling
                                  to degradation . . . . . . . . . . . . . 923
                   Hui Wang and   
                   Weili Fu and   
                Jae Hong Im and   
                Zengyi Zhou and   
          Samuel A. Santoro and   
               Vandana Iyer and   
           C. Mike DiPersio and   
               Qian-Chun Yu and   
              Vito Quaranta and   
               Abu Al-Mehdi and   
                Ruth J. Muschel   Tumor cell $ \alpha_3 \beta_1 $ integrin
                                  and vascular laminin-5 mediate pulmonary
                                  arrest and metastasis  . . . . . . . . . 935
                Hongmin Qin and   
           Dennis R. Diener and   
              Stefan Geimer and   
            Douglas G. Cole and   
              Joel L. Rosenbaum   Correction . . . . . . . . . . . . . . . 943

Journal of Cell Biology
Volume 164, Number 7, March, 2004

              Nicole LeBrasseur   Nerveless muscles shape up . . . . . . . ??
              Nicole LeBrasseur   Kinases speak from the Golgi . . . . . . ??
              Nicole LeBrasseur   No more division . . . . . . . . . . . . ??
              Nicole LeBrasseur   Ubiquitin cycles for Golgi fusion  . . . ??
              Nicole LeBrasseur   Two arms of TGF$ \beta $ signaling . . . ??
               William A. Wells   How transmembranes tell of their
                                  approach . . . . . . . . . . . . . . . . ??
               William A. Wells   All in the (network) family  . . . . . . ??
               William A. Wells   Snaring bugs in NETs . . . . . . . . . . ??
               William A. Wells   Surviving to remember  . . . . . . . . . ??
               William A. Wells   Actin as stairmaster . . . . . . . . . . ??
                Francis A. Barr   Golgi inheritance  . . . . . . . . . . . 955
              Takako Sasaki and   
      Reinhard Fässler and   
              Erhard Hohenester   Laminin  . . . . . . . . . . . . . . . . 959
         Sowmya Swaminathan and   
             Florian Kiendl and   
          Roman Körner and   
          Raffaella Lupetti and   
              Ludger Hengst and   
                Frauke Melchior   RanGAP1*SUMO1 is phosphorylated at the
                                  onset of mitosis and remains associated
                                  with RanBP2 upon NPC disassembly . . . . 965
             Yanzhuang Wang and   
                Ayano Satoh and   
              Graham Warren and   
                 Hemmo H. Meyer   VCIP135 acts as a deubiquitinating
                                  enzyme during p97--p47-mediated
                                  reassembly of mitotic Golgi fragments    973
         Masakiyo Sakaguchi and   
          Masahiro Miyazaki and   
          Hiroyuki Sonegawa and   
           Mariko Kashiwagi and   
                 Motoi Ohba and   
              Toshio Kuroki and   
            Masayoshi Namba and   
                     Nam-ho Huh   PKC$ \alpha $ mediates TGF$ \beta
                                  $-induced growth inhibition of human
                                  keratinocytes via phosphorylation of
                                  S100C/A11  . . . . . . . . . . . . . . . 979
          Alexandra Chittka and   
        Juan Carlos Arevalo and   
     Maria Rodriguez-Guzman and   
         Pilar Pérez and   
              Moses V. Chao and   
               Michael Sendtner   The p75NTR-interacting protein SC1
                                  inhibits cell cycle progression by
                                  transcriptional repression of cyclin E   985
              Erik L. Snapp and   
       Gretchen A. Reinhart and   
         Brigitte A. Bogert and   
Jennifer Lippincott-Schwartz and   
             Ramanujan S. Hegde   The organization of engaged and
                                  quiescent translocons in the endoplasmic
                                  reticulum of mammalian cells . . . . . . 997
       Christian Preisinger and   
             Benjamin Short and   
            Veerle De Corte and   
              Erik Bruyneel and   
             Alexander Haas and   
           Robert Kopajtich and   
              Jan Gettemans and   
                Francis A. Barr   YSK1 is activated by the Golgi matrix
                                  protein GM130 and plays a role in cell
                                  migration through its substrate 14-3-3$
                                  \zeta $  . . . . . . . . . . . . . . . . 1009
              Anna Schinzel and   
            Thomas Kaufmann and   
             Martin Schuler and   
           Jorge Martinalbo and   
                David Grubb and   
               Christoph Borner   Conformational control of Bax
                                  localization and apoptotic activity by
                                  Pro168 . . . . . . . . . . . . . . . . . 1021
            Guillaume Halet and   
            Richard Tunwell and   
         Scott J. Parkinson and   
                   John Carroll   Conventional PKCs regulate the temporal
                                  pattern of Ca$^{2+}$ oscillations at
                                  fertilization in mouse eggs  . . . . . . 1033
          Enrico S. Montana and   
              J. Troy Littleton   Characterization of a
                                  hypercontraction-induced myopathy in
                                  \bionameDrosophila caused by mutations
                                  in Mhc . . . . . . . . . . . . . . . . . 1045
             Henry C. Chang and   
               Michael Hull and   
                    Ira Mellman   The J-domain protein Rme-8 interacts
                                  with Hsc70 to control clathrin-dependent
                                  endocytosis in \bionameDrosophila  . . . 1055
            Andrew A. Peden and   
             Viola Oorschot and   
            Boris A. Hesser and   
             Cary D. Austin and   
        Richard H. Scheller and   
              Judith Klumperman   Localization of the AP-3 adaptor complex
                                  defines a novel endosomal exit site for
                                  lysosomal membrane proteins  . . . . . . 1065
         Terrance T. Kummer and   
             Thomas Misgeld and   
           Jeff W. Lichtman and   
                Joshua R. Sanes   Nerve-independent formation of a
                                  topologically complex postsynaptic
                                  apparatus  . . . . . . . . . . . . . . . 1077


Journal of Cell Biology
Volume 165, Number 1, April, 2004

               William A. Wells   Checking folding inside and out  . . . . ??
               William A. Wells   Don't digest the messenger . . . . . . . ??
               William A. Wells   Foci of decay  . . . . . . . . . . . . . ??
               William A. Wells   Brain construction goes straight . . . . ??
               William A. Wells   Formin a shmoo . . . . . . . . . . . . . ??
              Nicole LeBrasseur   RNA de-inhibition  . . . . . . . . . . . ??
              Nicole LeBrasseur   Cholesterol hastens Alzheimer's  . . . . ??
              Nicole LeBrasseur   The two faces of Mad2  . . . . . . . . . ??
              Nicole LeBrasseur   Assembling yeast complexes . . . . . . . ??
              Nicole LeBrasseur   Mass dedifferentiation . . . . . . . . . ??
                    Ira Mellman   Providing realistic access . . . . . . . 19
              Karen R. Dell and   
                 Ronald D. Vale   A tribute to Shinya Inoue and innovation
                                  in light microscopy  . . . . . . . . . . 21
             Laura Korhonen and   
                   Dan Lindholm   The ubiquitin proteasome system in
                                  synaptic and axonal degeneration . . . . 27
             Nicolas Cougot and   
             Sylvie Babajko and   
       Bertrand Séraphin   Cytoplasmic foci are sites of mRNA decay
                                  in human cells . . . . . . . . . . . . . 31
             Shilpa Vashist and   
                 Davis T. W. Ng   Misfolded proteins are sorted by a
                                  sequential checkpoint mechanism of ER
                                  quality control  . . . . . . . . . . . . 41
            Shushi Nagamori and   
          Irina N. Smirnova and   
               H. Ronald Kaback   Role of YidC in folding of polytopic
                                  membrane proteins  . . . . . . . . . . . 53
                     Lu Sun and   
                 Khaled Machaca   Ca$^{2+}_{cyt}$ negatively regulates the
                                  initiation of oocyte maturation  . . . . 63
                 Jingxia Li and   
                Haobin Chen and   
            Moon-Shong Tang and   
               Xianglin Shi and   
                Shantu Amin and   
              Dhimant Desai and   
                  Max Costa and   
                 Chuanshu Huang   PI-3K and Akt are mediators of AP-1
                                  induction by 5-MCDE in mouse epidermal
                                  Cl41 cells . . . . . . . . . . . . . . . 77
                 Xiang Fang and   
                    Hong Ji and   
                 Si-Wan Kim and   
                Jae-Il Park and   
           Travis G. Vaught and   
      Panos Z. Anastasiadis and   
       Malgorzata Ciesiolka and   
               Pierre D. McCrea   Vertebrate development requires ARVCF
                                  and p120 catenins and their interplay
                                  with RhoA and Rac  . . . . . . . . . . . 87
               Dina Matheos and   
            Metodi Metodiev and   
                Eric Muller and   
                David Stone and   
                   Mark D. Rose   Pheromone-induced polarization is
                                  dependent on the Fus3p MAPK acting
                                  through the formin Bni1p . . . . . . . . 99
           Matthew N. J. Seaman   Cargo-selective endosomal sorting for
                                  retrieval to the Golgi requires retromer 111
          Cecilia N. Arighi and   
           Lisa M. Hartnell and   
           Ruben C. Aguilar and   
              Carol R. Haft and   
             Juan S. Bonifacino   Role of the mammalian retromer in
                                  sorting of the cation-independent
                                  mannose $6$-phosphate receptor . . . . . 123
               Rebecca Dunn and   
            Deborah A. Klos and   
              Adam S. Adler and   
                    Linda Hicke   The C2 domain of the Rsp5 ubiquitin
                                  ligase binds membrane phosphoinositides
                                  and directs ubiquitination of endosomal
                                  cargo  . . . . . . . . . . . . . . . . . 135
                 Kyoko Itoh and   
                 Ling Cheng and   
            Yoshimasa Kamei and   
             Shinji Fushiki and   
         Hiroyuki Kamiguchi and   
               Paul Gutwein and   
           Alexander Stoeck and   
               Bernd Arnold and   
             Peter Altevogt and   
                   Vance Lemmon   Brain development in mice lacking L1--L1
                                  homophilic adhesion  . . . . . . . . . . 145
      Vladimir I. Titorenko and   
         Richard A. Rachubinski   Correction . . . . . . . . . . . . . . . 155

Journal of Cell Biology
Volume 165, Number 2, April, 2004

              Nicole LeBrasseur   Lethargic mitochondria are left out  . . ??
              Nicole LeBrasseur   Arpless comets are fascin-ating  . . . . ??
              Nicole LeBrasseur   PKCs pick through Ca$^{2+}$  . . . . . . ??
              Nicole LeBrasseur   Next vesicle SNAP'd up . . . . . . . . . ??
              Nicole LeBrasseur   Tracking transcripts . . . . . . . . . . ??
               William A. Wells   Rafting across polarized cells . . . . . ??
               William A. Wells   Myc conquers all . . . . . . . . . . . . ??
               William A. Wells   Telomeres together . . . . . . . . . . . ??
               William A. Wells   Being intolerant of tumors . . . . . . . ??
               William A. Wells   Get out! And don't come back!  . . . . . ??
                Mark Herlan and   
      Carsten Bornhövd and   
                   Kai Hell and   
             Walter Neupert and   
            Andreas S. Reichert   Alternative topogenesis of Mgm1 and
                                  mitochondrial morphology depend on ATP
                                  and a functional import motor  . . . . . 167
          Katja Köhler and   
             Daniel Louvard and   
                 Ahmed Zahraoui   Rab13 regulates PKA signaling during
                                  tight junction assembly  . . . . . . . . 175
             Maren Oehlmann and   
              Alan J. Score and   
                 J. Julian Blow   The role of Cdc6 in ensuring complete
                                  genome licensing and S phase checkpoint
                                  activation . . . . . . . . . . . . . . . 181
             Chris Molenaar and   
             Abadir Abdulle and   
                 Aarti Gena and   
              Hans J. Tanke and   
               Roeland W. Dirks   Poly(A) $^+$ RNAs roam the cell nucleus
                                  and pass through speckle domains in
                                  transcriptionally active and inactive
                                  cells  . . . . . . . . . . . . . . . . . 191
             Tracy L. Kress and   
              Young J. Yoon and   
              Kimberly L. Mowry   Nuclear RNP complex assembly initiates
                                  cytoplasmic RNA localization . . . . . . 203
        Martin van der Laan and   
          Philipp Bechtluft and   
                   Stef Kol and   
                Nico Nouwen and   
          Arnold J. M. Driessen   F$_1$ F$_0$ ATP synthase subunit c is a
                                  substrate of the novel YidC pathway for
                                  membrane protein biogenesis  . . . . . . 213
               Paolo Pinton and   
                   Sara Leo and   
      Mariusz R. Wieckowski and   
     Giulietta Di Benedetto and   
                Rosario Rizzuto   Long-term modulation of mitochondrial
                                  Ca$^{2+}$ signals by protein kinase C
                                  isozymes . . . . . . . . . . . . . . . . 223
         William M. Brieher and   
          Margaret Coughlin and   
           Timothy J. Mitchison   Fascin-mediated propulsion of
                                  \bionameListeria monocytogenes
                                  independent of frequent nucleation by
                                  the Arp2/3 complex . . . . . . . . . . . 233
            Satoshi Komatsu and   
                   Mitsuo Ikebe   ZIP kinase is responsible for the
                                  phosphorylation of myosin II and
                                  necessary for cell motility in mammalian
                                  fibroblasts  . . . . . . . . . . . . . . 243
           Noriko Takahashi and   
        Hiroyasu Hatakeyama and   
                Haruo Okado and   
                 Akiko Miwa and   
           Takuya Kishimoto and   
             Tatsuya Kojima and   
                  Teruo Abe and   
                    Haruo Kasai   Sequential exocytosis of insulin
                                  granules is associated with
                                  redistribution of SNAP25 . . . . . . . . 255
          Carolyn N. Wrobel and   
            Jayanta Debnath and   
                    Eva Lin and   
            Sean Beausoleil and   
         Martine F. Roussel and   
                 Joan S. Brugge   Autocrine CSF-1R activation promotes
                                  Src-dependent disruption of mammary
                                  epithelial architecture  . . . . . . . . 263
             Yuji Yamaguchi and   
              Satoshi Itami and   
            Hidenori Watabe and   
          Ken-ichi Yasumoto and   
       Zalfa A. Abdel-Malek and   
                Tateki Kubo and   
    François Rouzaud and   
           Atsushi Tanemura and   
         Kunihiko Yoshikawa and   
             Vincent J. Hearing   Mesenchymal-epithelial interactions in
                                  the skin . . . . . . . . . . . . . . . . 275

Journal of Cell Biology
Volume 165, Number 3, May, 2004

               William A. Wells   An anchor for motoring . . . . . . . . . ??
               William A. Wells   Arg links actin and microtubules . . . . ??
               William A. Wells   A caspase for stress . . . . . . . . . . ??
               William A. Wells   Monomeric myosin anchoring . . . . . . . ??
               William A. Wells   Sensing detachment . . . . . . . . . . . ??
              Nicole LeBrasseur   Intimacy is a cellular turn-on . . . . . ??
              Nicole LeBrasseur   Fighting foreigners prevents
                                  self-destruction . . . . . . . . . . . . ??
              Nicole LeBrasseur   A Rho for the kinetochore  . . . . . . . ??
              Nicole LeBrasseur   Death comes in small packages  . . . . . ??
              Nicole LeBrasseur   Fat and bone . . . . . . . . . . . . . . ??
                 Kendall Powell   All systems go . . . . . . . . . . . . . 299
      Maddalena de Virgilio and   
         William B. Kiosses and   
             Sanford J. Shattil   Proximal, selective, and dynamic
                                  interactions between integrin $ \alpha
                                  $IIb$ \beta $3 and protein tyrosine
                                  kinases in living cells  . . . . . . . . 305
              Cynthia Y. He and   
                Helen H. Ho and   
               Joerg Malsam and   
            Cecile Chalouni and   
        Christopher M. West and   
            Elisabetta Ullu and   
               Derek Toomre and   
                  Graham Warren   Golgi duplication in Trypanosoma brucei  313
           Matthew D. Smith and   
            Caleb M. Rounds and   
                   Fei Wang and   
                Kunhua Chen and   
          Meshack Afitlhile and   
               Danny J. Schnell   atToc159 is a selective transit peptide
                                  receptor for the import of
                                  nucleus-encoded chloroplast proteins . . 323
        Christina A. Wilson and   
            Diane D. Murphy and   
          Benoit I. Giasson and   
                  Bin Zhang and   
        John Q. Trojanowski and   
             Virginia M.-Y. Lee   Degradative organelles containing
                                  mislocalized $ \alpha $- and $ \beta
                                  $-synuclein proliferate in presenilin-1
                                  null neurons . . . . . . . . . . . . . . 335
             Junichi Hitomi and   
           Taiichi Katayama and   
              Yutaka Eguchi and   
               Takashi Kudo and   
           Manabu Taniguchi and   
           Yoshihisa Koyama and   
            Takayuki Manabe and   
           Satoru Yamagishi and   
               Yoshio Bando and   
          Kazunori Imaizumi and   
        Yoshihide Tsujimoto and   
                 Masaya Tohyama   Involvement of caspase-4 in endoplasmic
                                  reticulum stress-induced apoptosis and
                                  A$ \beta $-induced cell death  . . . . . 347
      Srinivasa Subramaniam and   
             Ute Zirrgiebel and   
Oliver von Bohlen und Halbach and   
               Jens Strelau and   
 Christine Laliberté and   
            David R. Kaplan and   
                 Klaus Unsicker   ERK activation promotes neuronal
                                  degeneration predominantly through
                                  plasma membrane damage and independently
                                  of caspase-3 . . . . . . . . . . . . . . 357
        M. Cecilia Subauste and   
              Olivier Pertz and   
          Eileen D. Adamson and   
      Christopher E. Turner and   
             Sachiko Junger and   
                  Klaus M. Hahn   Vinculin modulation of paxillin--FAK
                                  interactions regulates ERK to control
                                  survival and motility  . . . . . . . . . 371
          Elizabeth Gaskins and   
                Stacey Gilk and   
           Nicolette DeVore and   
                  Tara Mann and   
                  Gary Ward and   
                    Con Beckers   Identification of the membrane receptor
                                  of a class XIV myosin in Toxoplasma
                                  gondii . . . . . . . . . . . . . . . . . 383
           Matthew J. Tyska and   
               Mark S. Mooseker   A role for myosin-1A in the localization
                                  of a brush border disaccharidase . . . . 395
              Ann L. Miller and   
              Yinxiang Wang and   
           Mark S. Mooseker and   
             Anthony J. Koleske   The Abl-related gene (Arg) requires its
                                  F-actin--microtubule cross-linking
                                  activity to regulate lamellipodial
                                  dynamics during fibroblast adhesion  . . 407
               Yi Hsing Lin and   
              Zee-Yong Park and   
                  Dayin Lin and   
         Anar A. Brahmbhatt and   
        Marie-Christine Rio and   
              John R. Yates and   
              Richard L. Klemke   Regulation of cell migration and
                                  survival by focal adhesion targeting of
                                  Lasp-1 . . . . . . . . . . . . . . . . . 421
             Mitsuru Horiki and   
            Takeshi Imamura and   
               Mina Okamoto and   
             Makoto Hayashi and   
                Junko Murai and   
                Akira Myoui and   
              Takahiro Ochi and   
             Kohei Miyazono and   
           Hideki Yoshikawa and   
               Noriyuki Tsumaki   Smad6\slash Smurf1 overexpression in
                                  cartilage delays chondrocyte hypertrophy
                                  and causes dwarfism with osteopenia  . . 433

Journal of Cell Biology
Volume 165, Number 4, May, 2004

              Nicole LeBrasseur   Fingers lay fibers . . . . . . . . . . . ??
              Nicole LeBrasseur   Sticky sugar . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Geminin halts DNA synthesis  . . . . . . ??
              Nicole LeBrasseur   Slingshot to the lamellipod  . . . . . . ??
              Nicole LeBrasseur   NG2$^+$ cells feed the brain . . . . . . ??
               William A. Wells   Tilt back to turn left . . . . . . . . . ??
               William A. Wells   Pulling the spindle into shape . . . . . ??
               William A. Wells   How to become a generalist again . . . . ??
               William A. Wells   Metabolism as a production line  . . . . ??
               William A. Wells   Making waves . . . . . . . . . . . . . . ??
              Irene M. Ward and   
  Bernardo Reina-San-Martin and   
            Alexandru Olaru and   
                   Kay Minn and   
                Koji Tamada and   
               Julie S. Lau and   
           Marilia Cascalho and   
               Lieping Chen and   
          Andre Nussenzweig and   
               Ferenc Livak and   
      Michel C. Nussenzweig and   
                    Junjie Chen   53BP1 is required for class switch
                                  recombination  . . . . . . . . . . . . . 459
        Kyoko Nagata-Ohashi and   
                Yusaku Ohta and   
             Kazumichi Goto and   
               Shuhei Chiba and   
                 Reiko Mori and   
            Michiru Nishita and   
            Kazumasa Ohashi and   
          Kazuyoshi Kousaka and   
           Akihiro Iwamatsu and   
               Ryusuke Niwa and   
             Tadashi Uemura and   
                 Kensaku Mizuno   A pathway of neuregulin-induced
                                  activation of cofilin-phosphatase
                                  Slingshot and cofilin in lamellipodia    465
          Marina Melixetian and   
           Andrea Ballabeni and   
              Laura Masiero and   
         Patrizia Gasparini and   
          Raffaella Zamponi and   
                Jiri Bartek and   
                 Jiri Lukas and   
                 Kristian Helin   Loss of Geminin induces rereplication in
                                  the presence of functional p53 . . . . . 473
               Kris M. Mann and   
             Jenna Lynn Ray and   
             Edward S. Moon and   
            Kristin M. Sass and   
                 Mark R. Benson   Calcineurin initiates smooth muscle
                                  differentiation in neural crest stem
                                  cells  . . . . . . . . . . . . . . . . . 483
         Pamela J. Woodring and   
          Jill Meisenhelder and   
             Sam A. Johnson and   
               Guo-Lei Zhou and   
              Jeffrey Field and   
                Kavita Shah and   
            Friedhelm Bladt and   
                Tony Pawson and   
                Masaru Niki and   
        Pier Paolo Pandolfi and   
            Jean Y. J. Wang and   
                    Tony Hunter   c-Abl phosphorylates Dok1 to promote
                                  filopodia during cell spreading  . . . . 493
              Annie Cartaud and   
            Laure Strochlic and   
              Manuel Guerra and   
        Beno\^\it Blanchard and   
         Monique Lambergeon and   
                Eric Krejci and   
               Jean Cartaud and   
                   Claire Legay   MuSK is required for anchoring
                                  acetylcholinesterase at the
                                  neuromuscular junction . . . . . . . . . 505
              Takuji Tanoue and   
             Masatoshi Takeichi   Mammalian Fat1 cadherin regulates actin
                                  dynamics and cell--cell contact  . . . . 517
               Iwona Bucior and   
            Simon Scheuring and   
              Andreas Engel and   
                  Max M. Burger   Carbohydrate--carbohydrate interaction
                                  provides adhesion force and specificity
                                  for cellular recognition . . . . . . . . 529
             Satoshi Yamaji and   
             Atsushi Suzuki and   
             Heiwa Kanamori and   
             Wataru Mishima and   
            Ryusuke Yoshimi and   
          Hirotaka Takasaki and   
           Maki Takabayashi and   
        Katsumichi Fujimaki and   
              Shin Fujisawa and   
                Shigeo Ohno and   
           Yoshiaki Ishigatsubo   Affixin interacts with $ \alpha
                                  $-actinin and mediates integrin
                                  signaling for reorganization of F-actin
                                  induced by initial cell--substrate
                                  interaction  . . . . . . . . . . . . . . 539
         Elizabeth G. Canty and   
                  Yinhui Lu and   
           Roger S. Meadows and   
            Michael K. Shaw and   
            David F. Holmes and   
                 Karl E. Kadler   Coalignment of plasma membrane channels
                                  and protrusions (fibripositors)
                                  specifies the parallelism of tendon  . . 553
     Annette E. Rünker and   
                Igor Kobsar and   
               Torsten Fink and   
             Gabriele Loers and   
             Thomas Tilling and   
             Peggy Putthoff and   
             Carsten Wessig and   
             Rudolf Martini and   
              Melitta Schachner   Pathology of a mouse mutation in
                                  peripheral myelin protein P0 is
                                  characteristic of a severe and early
                                  onset form of human
                                  Charcot--Marie--Tooth type 1B disorder   565
            Adan A. Aguirre and   
         Ramesh Chittajallu and   
         Shibeshih Belachew and   
                 Vittorio Gallo   NG2-expressing cells in the
                                  subventricular zone are type C-like
                                  cells and contribute to interneuron
                                  generation in the postnatal hippocampus  575
             Andreas Wodarz and   
            Andreas Ramrath and   
            Alexandra Grimm and   
                Elisabeth Knust   Correction . . . . . . . . . . . . . . . 591
      Srinivasa Subramaniam and   
             Ute Zirrgiebel and   
Oliver von Bohlen und Halbach and   
               Jens Strelau and   
 Christine Laliberté and   
            David R. Kaplan and   
                 Klaus Unsicker   Correction . . . . . . . . . . . . . . . 593

Journal of Cell Biology
Volume 165, Number 5, June, 2004

             Aparna Sreenivasan   Pulling on a cytokine  . . . . . . . . . ??
             Aparna Sreenivasan   Mineralized mice . . . . . . . . . . . . ??
             Aparna Sreenivasan   An exit exchanger  . . . . . . . . . . . ??
             Aparna Sreenivasan   Fast rafting . . . . . . . . . . . . . . ??
             Aparna Sreenivasan   Building centrioles  . . . . . . . . . . ??
              Nicole LeBrasseur   The pore--transcription connection . . . ??
              Nicole LeBrasseur   Immune to autoimmunity . . . . . . . . . ??
              Nicole LeBrasseur   Uncertainty in structures  . . . . . . . ??
              Nicole LeBrasseur   Pollen spares all but self . . . . . . . ??
              Nicole LeBrasseur   Cells step back in time  . . . . . . . . ??
             P. Todd Stukenberg   Triggering p53 after cytokinesis failure 607
                Yumi Uetake and   
              Greenfield Sluder   Cell cycle progression after cleavage
                                  failure  . . . . . . . . . . . . . . . . 609
            Yoichi Miyamoto and   
             Takuya Saiwaki and   
          Junichi Yamashita and   
           Yoshinari Yasuda and   
               Ippei Kotera and   
            Satoshi Shibata and   
             Masaki Shigeta and   
            Yasushi Hiraoka and   
           Tokuko Haraguchi and   
               Yoshihiro Yoneda   Cellular stresses induce the nuclear
                                  accumulation of importin $ \alpha $ and
                                  cause a conventional nuclear import
                                  block  . . . . . . . . . . . . . . . . . 617
             Monzur Murshed and   
           Thorsten Schinke and   
              Marc D. McKee and   
                Gerard Karsenty   Extracellular matrix mineralization is
                                  regulated locally; different roles of
                                  two gla-containing proteins  . . . . . . 625
         Dimitrios Cakouros and   
            Tasman J. Daish and   
                   Sharad Kumar   Ecdysone receptor directly binds the
                                  promoter of the \bionameDrosophila
                                  caspase dronc, regulating its expression
                                  in specific tissues  . . . . . . . . . . 631
           Kousuke Kasahara and   
              Yuji Nakayama and   
               Kikuko Ikeda and   
             Yuka Fukushima and   
            Daisuke Matsuda and   
            Shinya Horimoto and   
                Naoto Yamaguchi   Trafficking of Lyn through the Golgi
                                  caveolin involves the charged residues
                                  on $ \alpha $E and $ \alpha $I helices
                                  in the kinase domain . . . . . . . . . . 641
       Gustavo Arrizabalaga and   
                 Felix Ruiz and   
              Silvia Moreno and   
              John C. Boothroyd   Ionophore-resistant mutant of Toxoplasma
                                  gondii reveals involvement of a
                                  sodium/hydrogen exchanger in calcium
                                  regulation . . . . . . . . . . . . . . . 653
              Kumi Matsuura and   
           Paul A. Lefebvre and   
               Ritsu Kamiya and   
                Masafumi Hirono   Bld10p, a novel protein essential for
                                  basal body assembly in Chlamydomonas . . 663
     Maruxa Martinez-Campos and   
               Renata Basto and   
                James Baker and   
             Maurice Kernan and   
                 Jordan W. Raff   The \bionameDrosophila pericentrin-like
                                  protein is essential for cilia/flagella
                                  function, but appears to be dispensable
                                  for mitosis  . . . . . . . . . . . . . . 673
               Fumio Motegi and   
           Mithilesh Mishra and   
   Mohan K. Balasubramanian and   
                  Issei Mabuchi   Myosin-II reorganization during mitosis
                                  is controlled temporally by its
                                  dephosphorylation and spatially by Mid1
                                  in fission yeast . . . . . . . . . . . . 685
           Becket Feierbach and   
               Fulvia Verde and   
                     Fred Chang   Regulation of a formin complex by the
                                  microtubule plus end protein tea1p . . . 697
            Teruyuki Tanaka and   
           Finley F. Serneo and   
          Christine Higgins and   
        Michael J. Gambello and   
      Anthony Wynshaw-Boris and   
              Joseph G. Gleeson   Lis1 and doublecortin function with
                                  dynein to mediate coupling of the
                                  nucleus to the centrosome in neuronal
                                  migration  . . . . . . . . . . . . . . . 709
            Justin P. Annes and   
                   Yan Chen and   
             John S. Munger and   
               Daniel B. Rifkin   Integrin $ \alpha_V \beta_6 $-mediated
                                  activation of latent TGF-$ \beta $
                                  requires the latent TGF-$ \beta $
                                  binding protein-1  . . . . . . . . . . . 723
          Anne K. Kenworthy and   
        Benjamin J. Nichols and   
           Catha L. Remmert and   
           Glenn M. Hendrix and   
               Mukesh Kumar and   
          Joshua Zimmerberg and   
   Jennifer Lippincott-Schwartz   Dynamics of putative raft-associated
                                  proteins at the cell surface . . . . . . 735

Journal of Cell Biology
Volume 165, Number 6, June, 2004

             Aparna Sreenivasan   Zombie cells . . . . . . . . . . . . . . ??
             Aparna Sreenivasan   Actin gets Hip at the TGN  . . . . . . . ??
             Aparna Sreenivasan   Stuck in the divide  . . . . . . . . . . ??
             Aparna Sreenivasan   Mixed guidance . . . . . . . . . . . . . ??
             Aparna Sreenivasan   Tumors make do with less matrix  . . . . ??
               William A. Wells   Me write pretty one day  . . . . . . . . 757
         Creighton T. Tuzon and   
           Britta Borgstrom and   
           Dietmar Weilguny and   
               Richard Egel and   
      Julia Promisel Cooper and   
                   Olaf Nielsen   The fission yeast heterochromatin
                                  protein Rik1 is required for telomere
                                  clustering during meiosis  . . . . . . . 759
               Sara Salinas and   
Anne Briançon-Marjollet and   
           Guillaume Bossis and   
           Marie-Aude Lopez and   
            Marc Piechaczyk and   
   Isabelle Jariel-Encontre and   
                Anne Debant and   
             Robert A. Hipskind   SUMOylation regulates nucleo-cytoplasmic
                                  shuttling of Elk-1 . . . . . . . . . . . 767
         Vanessa S. Marsden and   
              Paul G. Ekert and   
             Mark Van Delft and   
              David L. Vaux and   
             Jerry M. Adams and   
               Andreas Strasser   Bcl-2-regulated apoptosis and cytochrome
                                  c release can occur independently of
                                  both caspase-2 and caspase-9 . . . . . . 775
          Sebastien Carreno and   
Åsa E. Engqvist-Goldstein and   
            Claire X. Zhang and   
           Kent L. McDonald and   
                David G. Drubin   Actin dynamics coupled to
                                  clathrin-coated vesicle formation at the
                                  trans-Golgi network  . . . . . . . . . . 781
        Susanna Ekholm-Reed and   
         Juan Méndez and   
             Donato Tedesco and   
          Anders Zetterberg and   
             Bruce Stillman and   
                 Steven I. Reed   Deregulation of cyclin E in human cells
                                  interferes with prereplication complex
                                  assembly . . . . . . . . . . . . . . . . 789
                  Wenhui Li and   
                 Soo-Mi Kim and   
                   Joon Lee and   
              William G. Dunphy   Absence of BLM leads to accumulation of
                                  chromosomal DNA breaks during both
                                  unperturbed and disrupted S phases . . . 801
            Alejandra Tomas and   
               Clare Futter and   
                Stephen E. Moss   Annexin 11 is required for midbody
                                  formation and completion of the terminal
                                  phase of cytokinesis . . . . . . . . . . 813
               Andreas Marg and   
                  Ying Shan and   
               Thomas Meyer and   
           Torsten Meissner and   
         Martin Brandenburg and   
                 Uwe Vinkemeier   Nucleocytoplasmic shuttling by
                                  nucleoporins Nup153 and Nup214 and
                                  CRM1-dependent nuclear export control
                                  the subcellular distribution of latent
                                  Stat1  . . . . . . . . . . . . . . . . . 823
              Paul G. Ekert and   
             Stuart H. Read and   
                 John Silke and   
         Vanessa S. Marsden and   
             Hitto Kaufmann and   
       Christine J. Hawkins and   
                Robert Gerl and   
               Sharad Kumar and   
                  David L. Vaux   Apaf-1 and caspase-9 accelerate
                                  apoptosis, but do not determine whether
                                  factor-deprived or drug-treated cells
                                  die  . . . . . . . . . . . . . . . . . . 835
               Jianying Luo and   
        Elizabeth A. Vallen and   
         Christopher Dravis and   
    Serguei E. Tcheperegine and   
                Becky Drees and   
                       Erfei Bi   Identification and functional analysis
                                  of the essential and regulatory light
                                  chains of the only type II myosin Myo1p
                                  in \bionameSaccharomyces cerevisiae  . . 843
               Limor Broday and   
             Irina Kolotuev and   
           Christine Didier and   
           Anindita Bhoumik and   
       Benjamin Podbilewicz and   
                    Ze'ev Ronai   The LIM domain protein UNC-95 is
                                  required for the assembly of muscle
                                  attachment structures and is regulated
                                  by the RING finger protein RNF-5 in
                                  \bionameC. elegans . . . . . . . . . . . 857
           Jakub M. Swiercz and   
               Rohini Kuner and   
              Stefan Offermanns   Plexin--B1\slash RhoGEF-mediated RhoA
                                  activation involves the receptor
                                  tyrosine kinase ErbB-2 . . . . . . . . . 869
                Jianbo Yang and   
           Matthew A. Price and   
         Cheryl L. Neudauer and   
         Christopher Wilson and   
            Soldano Ferrone and   
                   Hong Xia and   
                  Joji Iida and   
         Melanie A. Simpson and   
              James B. McCarthy   Melanoma chondroitin sulfate
                                  proteoglycan enhances FAK and ERK
                                  activation by distinct mechanisms  . . . 881
               Osamu Nagano and   
             Daizo Murakami and   
            Dieter Hartmann and   
           Bart de Strooper and   
                Paul Saftig and   
           Takeshi Iwatsubo and   
            Motowo Nakajima and   
         Masanori Shinohara and   
                  Hideyuki Saya   Cell--matrix interaction via CD44 is
                                  independently regulated by different
                                  metalloproteinases activated in response
                                  to extracellular Ca$^{2+}$ influx and
                                  PKC activation . . . . . . . . . . . . . 893


Journal of Cell Biology
Volume 166, Number 1, July, 2004

             Aparna Sreenivasan   Fusion at the front  . . . . . . . . . . ??
             Aparna Sreenivasan   Anti-angiogenesis is anti-actin  . . . . ??
             Aparna Sreenivasan   Calcium signals from outside . . . . . . ??
             Aparna Sreenivasan   Myelin movement  . . . . . . . . . . . . ??
             Aparna Sreenivasan   Orbit(ing) the furrow  . . . . . . . . . ??
               William A. Wells   Moving while sticking  . . . . . . . . . ??
               William A. Wells   How a channel springs open . . . . . . . ??
               William A. Wells   Caterpillar compaction . . . . . . . . . ??
               William A. Wells   A message before dying . . . . . . . . . ??
               William A. Wells   Prions in packages . . . . . . . . . . . ??
               Mike Rossner and   
              Kenneth M. Yamada   What's in a picture? The temptation of
                                  image manipulation . . . . . . . . . . . 11
          Toshiaki Sakisaka and   
               Takeshi Baba and   
            Shintaro Tanaka and   
             Genkichi Izumi and   
              Masato Yasumi and   
                  Yoshimi Takai   Regulation of SNAREs by tomosyn and ROCK 17
       Vincent van den Boom and   
        Elisabetta Citterio and   
        Deborah Hoogstraten and   
            Angelika Zotter and   
             Jean-Marc Egly and   
   Wiggert A. van Cappellen and   
      Jan H. J. Hoeijmakers and   
     Adriaan B. Houtsmuller and   
                  Wim Vermeulen   DNA damage stabilizes interaction of CSB
                                  with the transcription elongation
                                  machinery  . . . . . . . . . . . . . . . 27
            Philippe Blache and   
       Marc van de Wetering and   
             Isabelle Duluc and   
               Claire Domon and   
             Philippe Berta and   
      Jean-Noël Freund and   
               Hans Clevers and   
                   Philippe Jay   SOX9 is an intestine crypt transcription
                                  factor, is regulated by the Wnt pathway,
                                  and represses the CDX2 and MUC2 genes    37
         Yoshihiro H. Inoue and   
         Matthew S. Savoian and   
               Takao Suzuki and   
  Endre Máthé and   
        Masa-Toshi Yamamoto and   
                David M. Glover   Mutations in orbit/mast reveal that the
                                  central spindle is comprised of two
                                  microtubule populations, those that
                                  initiate cleavage and those that
                                  propagate furrow ingression  . . . . . . 49
         Pier Paolo D'Avino and   
         Matthew S. Savoian and   
                David M. Glover   Mutations in sticky lead to defective
                                  organization of the contractile ring
                                  during cytokinesis and are enhanced by
                                  Rho and suppressed by Rac  . . . . . . . 61
          Neetu Gupta-Rossi and   
             Emmanuelle Six and   
               Odile LeBail and   
Frédérique Logeat and   
        Patricia Chastagner and   
                 Annie Olry and   
          Alain Israël and   
                  Christel Brou   Monoubiquitination and endocytosis
                                  direct $ \gamma $-secretase cleavage of
                                  activated Notch receptor . . . . . . . . 73
             Takashi Fujita and   
             Yasutaka Azuma and   
               Ryo Fukuyama and   
               Yuji Hattori and   
           Carolina Yoshida and   
                Masao Koida and   
             Kiyokazu Ogita and   
               Toshihisa Komori   Runx2 induces osteoblast and chondrocyte
                                  differentiation and enhances their
                                  migration by coupling with PI3K--Akt
                                  signaling  . . . . . . . . . . . . . . . 85
                Gregory Bix and   
                    Jian Fu and   
            Eva M. Gonzalez and   
                Laura Macro and   
                 Amy Barker and   
            Shelly Campbell and   
             Mary M. Zutter and   
          Samuel A. Santoro and   
              Jiyeun K. Kim and   
      Magnus Höök and   
            Charles C. Reed and   
                Renato V. Iozzo   Endorepellin causes endothelial cell
                                  disassembly of actin cytoskeleton and
                                  focal adhesions through $ \alpha $2$
                                  \beta $1 integrin  . . . . . . . . . . . 97
               Rosa Caroppo and   
             Andrea Gerbino and   
          Gregorio Fistetto and   
            Matilde Colella and   
        Lucantonio Debellis and   
         Aldebaran M. Hofer and   
                  Silvana Curci   Extracellular calcium acts as a ``third
                                  messenger'' to regulate enzyme and
                                  alkaline secretion . . . . . . . . . . . 111
             Julia M. Edgar and   
            Mark McLaughlin and   
                Donald Yool and   
              Su-Chun Zhang and   
             Jill H. Fowler and   
              Paul Montague and   
         Jennifer A. Barrie and   
        Mailis C. McCulloch and   
              Ian D. Duncan and   
              James Garbern and   
              Klaus A. Nave and   
               Ian R. Griffiths   Oligodendroglial modulation of fast
                                  axonal transport in a mouse model of
                                  hereditary spastic paraplegia  . . . . . 121
             Janice Murtagh and   
             Emmett McArdle and   
              Emer Gilligan and   
             Laura Thornton and   
              Fiona Furlong and   
                  Finian Martin   Organization of mammary epithelial cells
                                  into $3$D acinar structures requires
                                  glucocorticoid and JNK signaling . . . . 133

Journal of Cell Biology
Volume 166, Number 2, July, 2004

              Nicole LeBrasseur   A synaptic scaffold quiets T cells . . . ??
              Nicole LeBrasseur   Another passenger on chromosomes . . . . ??
              Nicole LeBrasseur   Loopy for telomeres  . . . . . . . . . . ??
              Nicole LeBrasseur   Integrins talk to N-cadherin . . . . . . ??
              Nicole LeBrasseur   E-cadherin evades endocytosis  . . . . . ??
               William A. Wells   Cohesin gets pushed around . . . . . . . ??
               William A. Wells   Flat-out pushing by actin  . . . . . . . ??
               William A. Wells   Xylogen makes plant channels . . . . . . ??
               William A. Wells   Mini inhibition  . . . . . . . . . . . . ??
               William A. Wells   Reprogramming by virus . . . . . . . . . ??
            Michael D. Schaller   FAK and paxillin . . . . . . . . . . . . 157
           Tatiana Nikitina and   
        Christopher L. Woodcock   Closed chromatin loops at the ends of
                                  chromosomes  . . . . . . . . . . . . . . 161
           Ulrike Gruneberg and   
          Rüdiger Neef and   
                Reiko Honda and   
              Erich A. Nigg and   
                Francis A. Barr   Relocation of Aurora B from centromeres
                                  to the central spindle at the metaphase
                                  to anaphase transition requires MKlp2    167
              Ramnik Xavier and   
         Shahrooz Rabizadeh and   
          Kazuhiro Ishiguro and   
                 Niko Andre and   
           J. Bernabe Ortiz and   
            Heather Wachtel and   
            David G. Morris and   
        Marco Lopez-Ilasaca and   
             Albert C. Shaw and   
              Wojciech Swat and   
                     Brian Seed   Discs large (Dlg1) complexes in
                                  lymphocyte activation  . . . . . . . . . 173
              Reto Gassmann and   
               Ana Carvalho and   
       Alexander J. Henzing and   
           Sandrine Ruchaud and   
           Damien F. Hudson and   
                Reiko Honda and   
              Erich A. Nigg and   
        Dietlind L. Gerloff and   
            William C. Earnshaw   Borealin . . . . . . . . . . . . . . . . 179
                   Rui Chen and   
           Ignacio Valencia and   
                  Fei Zhong and   
            Karen S. McColl and   
       H. Llewelyn Roderick and   
          Martin D. Bootman and   
        Michael J. Berridge and   
           Stuart J. Conway and   
           Andrew B. Holmes and   
         Gregory A. Mignery and   
             Patricio Velez and   
           Clark W. Distelhorst   Bcl-2 functionally interacts with
                                  inositol 1,4,5-trisphosphate receptors
                                  to regulate calcium release from the ER
                                  in response to inositol
                                  1,4,5-trisphosphate  . . . . . . . . . . 193
            Prasenjit Mitra and   
              Yingjie Zhang and   
             Lucia E. Rameh and   
           Maria P. Ivshina and   
            Dannel McCollum and   
            John J. Nunnari and   
       Gregory M. Hendricks and   
             Monica L. Kerr and   
              Seth J. Field and   
           Lewis C. Cantley and   
                 Alonzo H. Ross   A novel phosphatidylinositol(3,4,5)P$_3$
                                  pathway in fission yeast . . . . . . . . 205
        Laura S. Harrington and   
            Greg M. Findlay and   
                  Alex Gray and   
         Tatiana Tolkacheva and   
             Simon Wigfield and   
              Heike Rebholz and   
               Jill Barnett and   
             Nick R. Leslie and   
                Susan Cheng and   
          Peter R. Shepherd and   
                  Ivan Gout and   
            C. Peter Downes and   
                Richard F. Lamb   The TSC1-2 tumor suppressor controls
                                  insulin--PI3K signaling via regulation
                                  of IRS proteins  . . . . . . . . . . . . 213
       Laurence Bougn\`eres and   
Stéphane E. Girardin and   
              Scott A. Weed and   
         Andrei V. Karginov and   
Jean-Christophe Olivo-Marin and   
          J. Thomas Parsons and   
     Philippe J. Sansonetti and   
             Guy Tran Van Nhieu   Cortactin and Crk cooperate to trigger
                                  actin polymerization during Shigella
                                  invasion of epithelial cells . . . . . . 225
             Genkichi Izumi and   
          Toshiaki Sakisaka and   
               Takeshi Baba and   
            Shintaro Tanaka and   
              Koji Morimoto and   
                  Yoshimi Takai   Endocytosis of E-cadherin regulated by
                                  Rac and Cdc42 small G proteins through
                                  IQGAP1 and actin filaments . . . . . . . 237
              Bill Adolfsen and   
          Sudipta Saraswati and   
         Motojiro Yoshihara and   
              J. Troy Littleton   Synaptotagmins are trafficked to
                                  distinct subcellular domains including
                                  the postsynaptic compartment . . . . . . 249
        Alex I. Chernyavsky and   
             Juan Arredondo and   
           Jürgen Wess and   
             Evert Karlsson and   
               Sergei A. Grando   Novel signaling pathways mediating
                                  reciprocal control of keratinocyte
                                  migration and wound epithelialization
                                  through M$_3$ and M$_4$ muscarinic
                                  receptors  . . . . . . . . . . . . . . . 261
M. Angelica Martinez Gakidis and   
             Xavier Cullere and   
              Timothy Olson and   
        Julie L. Wilsbacher and   
                  Bin Zhang and   
            Sheri L. Moores and   
                  Klaus Ley and   
              Wojciech Swat and   
              Tanya Mayadas and   
                 Joan S. Brugge   Vav GEFs are required for $ \beta_2 $
                                  integrin-dependent functions of
                                  neutrophils  . . . . . . . . . . . . . . 273
                Hajime Yano and   
              Yuichi Mazaki and   
             Kazuo Kurokawa and   
            Steven K. Hanks and   
          Michiyuki Matsuda and   
                  Hisataka Sabe   Roles played by a subset of integrin
                                  signaling molecules in cadherin-based
                                  cell--cell adhesion  . . . . . . . . . . 283

Journal of Cell Biology
Volume 166, Number 3, August, 2004

               William A. Wells   A muscular path to quiescence  . . . . . ??
               William A. Wells   Do yeast apoptose? . . . . . . . . . . . ??
               William A. Wells   Integrins make a choice  . . . . . . . . ??
               William A. Wells   Freedom from substrate . . . . . . . . . ??
               William A. Wells   Rho in podosomes . . . . . . . . . . . . ??
              Nicole LeBrasseur   BARS takes Golgi apart . . . . . . . . . ??
              Nicole LeBrasseur   With their dying breath  . . . . . . . . ??
              Nicole LeBrasseur   Arp2\slash 3 for axon turning  . . . . . ??
              Nicole LeBrasseur   Death takes a holiday  . . . . . . . . . ??
              Nicole LeBrasseur   Running Mad-ly into mitosis  . . . . . . ??
              Nicole LeBrasseur   West Meets East  . . . . . . . . . . . . 308
             Robert Wysocki and   
                Stephen J. Kron   Yeast cell death during DNA damage
                                  arrest is independent of caspase or
                                  reactive oxygen species  . . . . . . . . 311
        Rebecca L. Berdeaux and   
  Begoña Díaz and   
                   Lomi Kim and   
               G. Steven Martin   Active Rho is localized to podosomes
                                  induced by oncogenic Src and is required
                                  for their assembly and function  . . . . 317
          Charissa D. Ellis and   
                  Fudi Wang and   
        Colin W. MacDiarmid and   
              Suzanne Clark and   
               Thomas Lyons and   
                  David J. Eide   Zinc and the Msc2 zinc transporter
                                  protein are required for endoplasmic
                                  reticulum function . . . . . . . . . . . 325
   Henrik Òstergaard and   
        Christine Tachibana and   
               Jakob R. Winther   Monitoring disulfide bond formation in
                                  the eukaryotic cytosol . . . . . . . . . 337
            Peter S. Zammit and   
             Jon P. Golding and   
              Yosuke Nagata and   
       Valérie Hudon and   
       Terence A. Partridge and   
          Jonathan R. Beauchamp   Muscle satellite cells adopt divergent
                                  fates  . . . . . . . . . . . . . . . . . 347
             Stefan Liebner and   
             Anna Cattelino and   
            Radiosa Gallini and   
               Noemi Rudini and   
             Monica Iurlaro and   
            Stefano Piccolo and   
              Elisabetta Dejana   $ \beta $-Catenin is required for
                                  endothelial-mesenchymal transformation
                                  during heart cushion development in the
                                  mouse  . . . . . . . . . . . . . . . . . 359
            Sebastian Kreuz and   
           Daniela Siegmund and   
          Jost-Julian Rumpf and   
                Dierk Samel and   
            Martin Leverkus and   
             Ottmar Janssen and   
          Georg Häcker and   
   Oliver Dittrich-Breiholz and   
             Michael Kracht and   
            Peter Scheurich and   
                  Harald Wajant   NF$ \kappa $B activation by Fas is
                                  mediated through FADD, caspase-8, and
                                  RIP and is inhibited by FLIP . . . . . . 369
          Rachelle E. Toman and   
             Shawn G. Payne and   
       Kenneth R. Watterson and   
            Michael Maceyka and   
              Norman H. Lee and   
           Sheldon Milstien and   
             John W. Bigbee and   
                  Sarah Spiegel   Differential transactivation of
                                  sphingosine-$1$-phosphate receptors
                                  modulates NGF-induced neurite extension  381
           Tatsuro Fukuhara and   
             Kazuya Shimizu and   
           Tomomi Kawakatsu and   
            Taihei Fukuyama and   
              Yukiko Minami and   
             Tomoyuki Honda and   
            Takashi Hoshino and   
            Tomohiro Yamada and   
             Hisakazu Ogita and   
               Masato Okada and   
                  Yoshimi Takai   Activation of Cdc42 by trans
                                  interactions of the cell adhesion
                                  molecules nectins through c--Src and
                                  Cdc42-GEF FRG  . . . . . . . . . . . . . 393
              Hira Lal Goel and   
               Mara Fornaro and   
              Loredana Moro and   
             Natalia Teider and   
              Johng S. Rhim and   
               Michael King and   
              Lucia R. Languino   Selective modulation of type 1
                                  insulin-like growth factor receptor
                                  signaling and functions by $ \beta_1 $
                                  integrins  . . . . . . . . . . . . . . . 407
               Sam M. Janes and   
                  Fiona M. Watt   Switch from $ \alpha $v$ \beta $5 to $
                                  \alpha $v$ \beta $6 integrin expression
                                  protects squamous cell carcinomas from
                                  anoikis  . . . . . . . . . . . . . . . . 419
             Yanzhuang Wang and   
                Ayano Satoh and   
              Graham Warren and   
                 Hemmo H. Meyer   Correction . . . . . . . . . . . . . . . 433

Journal of Cell Biology
Volume 166, Number 4, August, 2004

              Nicole LeBrasseur   No endocytosis in the axonal entry . . . ??
              Nicole LeBrasseur   Antagonizing T cells . . . . . . . . . . ??
              Nicole LeBrasseur   Kif2a cures monopolar disorder . . . . . ??
              Nicole LeBrasseur   Ubiquitin stripping  . . . . . . . . . . ??
              Nicole LeBrasseur   Collagen for swallowing  . . . . . . . . ??
               William A. Wells   Bugs to the rescue . . . . . . . . . . . ??
               William A. Wells   Protein-only prions  . . . . . . . . . . ??
               William A. Wells   Channels rush in . . . . . . . . . . . . ??
               William A. Wells   Corralled by septin  . . . . . . . . . . ??
               William A. Wells   License to glue  . . . . . . . . . . . . ??
         Yoshikazu Imanishi and   
               Volker Gerke and   
           Krzysztof Palczewski   Retinosomes  . . . . . . . . . . . . . . 447
           David A. Solomon and   
        M. Cristina Cardoso and   
                Erik S. Knudsen   Dynamic targeting of the replication
                                  machinery to sites of DNA damage . . . . 455
             Jedidiah Gaetz and   
                Tarun M. Kapoor   Dynein\slash dynactin regulate metaphase
                                  spindle length by targeting
                                  depolymerizing activities to spindle
                                  poles  . . . . . . . . . . . . . . . . . 465
              Neil J. Ganem and   
               Duane A. Compton   The KinI kinesin Kif2a is required for
                                  bipolar spindle assembly through a
                                  functional relationship with MCAK  . . . 473
                  Nam-On Ku and   
                   Haian Fu and   
                 M. Bishr Omary   Raf-1 activation disrupts its binding to
                                  keratins during cell stress  . . . . . . 479
            John McCullough and   
          Michael J. Clague and   
             Sylvie Urbé   AMSH is an endosome-associated ubiquitin
                                  isopeptidase . . . . . . . . . . . . . . 487
            Mounia Guenatri and   
            Delphine Bailly and   
         Christ\`ele Maison and   
           Genevi\`eve Almouzni   Mouse centric and pericentric satellite
                                  repeats form distinct functional
                                  heterochromatin  . . . . . . . . . . . . 493
         Takahiro Matsusaka and   
                 Jonathon Pines   Chfr acts with the p38 stress kinases to
                                  block entry to mitosis in mammalian
                                  cells  . . . . . . . . . . . . . . . . . 507
           Alexei Mikhailov and   
              Mio Shinohara and   
                Conly L. Rieder   Topoisomerase II and histone deacetylase
                                  inhibitors delay the G2/M transition by
                                  triggering the p38 MAPK checkpoint
                                  pathway  . . . . . . . . . . . . . . . . 517
        Rüdiger Rudolf and   
             Marco Mongillo and   
  Paulo J. Magalhães and   
                  Tullio Pozzan   In vivo monitoring of Ca$^{2+}$ uptake
                                  into mitochondria of mouse skeletal
                                  muscle during contraction  . . . . . . . 527
               Susan Treves and   
   Clara Franzini-Armstrong and   
            Luca Moccagatta and   
         Christophe Arnoult and   
           Cristiano Grasso and   
                Adam Schrum and   
             Sylvie Ducreux and   
             Michael X. Zhu and   
        Katsuhiko Mikoshiba and   
             Thierry Girard and   
        Sophia Smida-Rezgui and   
              Michel Ronjat and   
              Francesco Zorzato   Junctate is a key element in calcium
                                  entry induced by activation of InsP$_3$
                                  receptors and/or calcium store depletion 537
               Sol Sotillos and   
María Teresa Díaz-Meco and   
               Eva Caminero and   
               Jorge Moscat and   
             Sonsoles Campuzano   DaPKC-dependent phosphorylation of
                                  Crumbs is required for epithelial cell
                                  polarity in \bionameDrosophila . . . . . 549
       Shin-ichiro Kitajiri and   
          Kanehisa Fukumoto and   
                Masaki Hata and   
            Hiroyuki Sasaki and   
            Tatsuya Katsuno and   
          Takayuki Nakagawa and   
                 Juichi Ito and   
          Shoichiro Tsukita and   
                Sachiko Tsukita   Radixin deficiency causes deafness
                                  associated with progressive degeneration
                                  of cochlear stereocilia  . . . . . . . . 559
         Marie-Pierre Fache and   
             Anissa Moussif and   
            Fanny Fernandes and   
              Pierre Giraud and   
   Juan José Garrido and   
Bénédicte Dargent   Endocytotic elimination and
                                  domain-selective tethering constitute a
                                  potential mechanism of protein
                                  segregation at the axonal initial
                                  segment  . . . . . . . . . . . . . . . . 571
                 Cenk Sumen and   
          Michael L. Dustin and   
                  Mark M. Davis   T cell receptor antagonism interferes
                                  with MHC clustering and integrin
                                  patterning during immunological synapse
                                  formation  . . . . . . . . . . . . . . . 579
          Hideaki Sumiyoshi and   
                    Niv Mor and   
                 Sui Y. Lee and   
               Stephen Doty and   
            Scott Henderson and   
             Shizuko Tanaka and   
         Hidekatsu Yoshioka and   
              Satish Rattan and   
              Francesco Ramirez   Esophageal muscle physiology and
                                  morphogenesis require assembly of a
                                  collagen XIX--rich basement membrane
                                  zone . . . . . . . . . . . . . . . . . . 591

Journal of Cell Biology
Volume 166, Number 5, August, 2004

           Manjari Mazumdar and   
           Suma Sundareshan and   
                    Tom Misteli   Human chromokinesin KIF4A functions in
                                  chromosome condensation and segregation  613
             Daigo Ishikawa and   
           Hayashi Yamamoto and   
             Yasushi Tamura and   
              Kaori Moritoh and   
                   Toshiya Endo   Two novel proteins in the mitochondrial
                                  outer membrane mediate $ \beta $-barrel
                                  protein assembly . . . . . . . . . . . . 621
           Michael E. Young and   
             John A. Cooper and   
               Paul C. Bridgman   Yeast actin patches are networks of
                                  branched actin filaments . . . . . . . . 629
              Agata Jurczyk and   
               Adam Gromley and   
              Sambra Redick and   
        Jovenal San Agustin and   
              George Witman and   
          Gregory J. Pazour and   
        Dorien J. M. Peters and   
                 Stephen Doxsey   Pericentrin forms a complex with
                                  intraflagellar transport proteins and
                                  polycystin-2 and is required for primary
                                  cilia assembly . . . . . . . . . . . . . 637
            Laurence Abrami and   
           Margaret Lindsay and   
           Robert G. Parton and   
          Stephen H. Leppla and   
          F. Gisou van der Goot   Membrane insertion of anthrax protective
                                  antigen and cytoplasmic delivery of
                                  lethal factor occur at different stages
                                  of the endocytic pathway . . . . . . . . 645
             Karen R. Groot and   
            Lisa M. Sevilla and   
             Kazunori Nishi and   
         Teresa DiColandrea and   
                  Fiona M. Watt   Kazrin, a novel periplakin-interacting
                                  protein associated with desmosomes and
                                  the keratinocyte plasma membrane . . . . 653
        Violaine Sée and   
          Nina K. M. Rajala and   
           David G. Spiller and   
            Michael R. H. White   Calcium-dependent regulation of the cell
                                  cycle via a novel MAPK-NF-$ \kappa $B
                                  pathway in Swiss 3T3 cells . . . . . . . 661
                    Ming Fu and   
       Vincent Chi Hang Lui and   
               Mai Har Sham and   
           Vassilis Pachnis and   
            Paul Kwong Hang Tam   Sonic hedgehog regulates the
                                  proliferation, differentiation, and
                                  migration of enteric neural crest cells
                                  in gut . . . . . . . . . . . . . . . . . 673
             Anthony J. Kee and   
            Galina Schevzov and   
    Visalini Nair-Shalliker and   
        C. Stephen Robinson and   
        Bernadette Vrhovski and   
             Majid Ghoddusi and   
                 Min Ru Qiu and   
              Jim J.-C. Lin and   
             Ron Weinberger and   
           Peter W. Gunning and   
               Edna C. Hardeman   Sorting of a nonmuscle tropomyosin to a
                                  novel cytoskeletal compartment in
                                  skeletal muscle results in muscular
                                  dystrophy  . . . . . . . . . . . . . . . 685
          Ghassan Mouneimne and   
                Lilian Soon and   
             Vera DesMarais and   
               Mazen Sidani and   
               Xiaoyan Song and   
               Shu-Chin Yip and   
              Mousumi Ghosh and   
                Robert Eddy and   
         Jonathan M. Backer and   
                 John Condeelis   Phospholipase C and cofilin are required
                                  for carcinoma cell directionality in
                                  response to EGF stimulation  . . . . . . 697
          David R. Mitchell and   
             Masako Nakatsugawa   Bend propagation drives central pair
                                  rotation in Chlamydomonas reinhardtii
                                  flagella . . . . . . . . . . . . . . . . 709
            Natalie Luhtala and   
                  Greg Odorizzi   Bro1 coordinates deubiquitination in the
                                  multivesicular body pathway by
                                  recruiting Doa4 to endosomes . . . . . . 717
    Nicole Schaeren-Wiemers and   
              Annick Bonnet and   
                Michael Erb and   
                  Beat Erne and   
                Udo Bartsch and   
               Frances Kern and   
                 Ned Mantei and   
              Diane Sherman and   
                     Ueli Suter   The raft-associated protein MAL is
                                  required for maintenance of proper
                                  axon--glia interactions in the central
                                  nervous system . . . . . . . . . . . . . 731
    Stéphanie Seveau and   
     Hél\`ene Bierne and   
    Stéphanie Giroux and   
Marie-Christine Prévost and   
                Pascale Cossart   Role of lipid rafts in E-cadherin- and
                                  HGF-R/Met-mediated entry of
                                  \bioname\bionameListeria monocytogenes
                                  into host cells  . . . . . . . . . . . . 743
                    Rabiya Tuma   Actin branches out in yeast  . . . . . . ??
                    Rabiya Tuma   Less kinesin, more condensation  . . . . ??
                    Rabiya Tuma   Calcium lights up cell cycle . . . . . . ??
                    Rabiya Tuma   Flagellar microtubules do the twist  . . ??
                    Rabiya Tuma   Pericentrin pivotal in primary cilia . . ??
              Nicole LeBrasseur   Swelling with tumors . . . . . . . . . . ??
              Nicole LeBrasseur   Shh is out on a limb . . . . . . . . . . ??
              Nicole LeBrasseur   Ping pong in the pore  . . . . . . . . . ??
              Nicole LeBrasseur   Division at right angles . . . . . . . . ??
              Nicole LeBrasseur   Getting to the inner circle  . . . . . . ??
          Ralph M. Steinman and   
                    Ira Mellman   The JEM and the JCB  . . . . . . . . . . 611

Journal of Cell Biology
Volume 166, Number 6, September, 2004

            Natashe Kireeva and   
          Margot Lakonishok and   
                Igor Kireev and   
             Tatsuya Hirano and   
              Andrew S. Belmont   Visualization of early chromosome
                                  condensation . . . . . . . . . . . . . . 775
      Anthony Kar Lun Leung and   
             Daniel Gerlich and   
                Gail Miller and   
                 Carol Lyon and   
                Yun Wah Lam and   
               David Lleres and   
            Nathalie Daigle and   
            Joost Zomerdijk and   
              Jan Ellenberg and   
                Angus I. Lamond   Quantitative kinetic analysis of
                                  nucleolar breakdown and reassembly
                                  during mitosis in live human cells . . . 787
             Sagar Sengupta and   
              Ana I. Robles and   
            Steven P. Linke and   
       Natasha I. Sinogeeva and   
                  Ran Zhang and   
                Remy Pedeux and   
              Irene M. Ward and   
             Arkady Celeste and   
   André Nussenzweig and   
                Junjie Chen and   
      Thanos D. Halazonetis and   
               Curtis C. Harris   Functional interaction between BLM
                                  helicase and 53BP1 in a Chk1-mediated
                                  pathway during S-phase arrest  . . . . . 801
               Daniele Zink and   
        Margarida D. Amaral and   
           Andreas Englmann and   
               Susanne Lang and   
             Luka A. Clarke and   
            Carsten Rudolph and   
                  Felix Alt and   
             Kathrin Luther and   
                 Carla Braz and   
             Nicolas Sadoni and   
          Joseph Rosenecker and   
             Dirk Schindelhauer   Transcription-dependent spatial
                                  arrangements of CFTR and adjacent genes
                                  in human cell nuclei . . . . . . . . . . 815
    Christopher E. Andoniou and   
          Daniel M. Andrews and   
              Mitali Manzur and   
 Paola Ricciardi-Castagnoli and   
      Mariapia A. Degli-Esposti   A novel checkpoint in the
                                  Bcl-2--regulated apoptotic pathway
                                  revealed by murine cytomegalovirus
                                  infection of dendritic cells . . . . . . 827
                 M. Bentele and   
                  I. Lavrik and   
                  M. Ulrich and   
       S. Stößer and   
             D. W. Heermann and   
                H. Kalthoff and   
              P. H. Krammer and   
                        R. Eils   Mathematical modeling reveals threshold
                                  mechanism in CD95-induced apoptosis  . . 839
   Jacqueline L. Vanderluit and   
          Kerry L. Ferguson and   
   Vassiliki Nikoletopoulou and   
               Maura Parker and   
         Vladimir Ruzhynsky and   
              Tania Alexson and   
        Stephen M. McNamara and   
              David S. Park and   
           Michael Rudnicki and   
                  Ruth S. Slack   p107 regulates neural precursor cells in
                                  the mammalian brain  . . . . . . . . . . 853
             Michael S. Huh and   
            Maura H. Parker and   
            Anthony Scim\`e and   
                Robin Parks and   
            Michael A. Rudnicki   Rb is required for progression through
                                  myogenic differentiation but not
                                  maintenance of terminal differentiation  865
             Adam J. Engler and   
         Maureen A. Griffin and   
                 Shamik Sen and   
  Carsten G. Bönnemann and   
             H. Lee Sweeney and   
              Dennis E. Discher   Myotubes differentiate optimally on
                                  substrates with tissue-like stiffness    877
     Roland Wedlich-Soldner and   
           Stephanie C. Wai and   
             Thomas Schmidt and   
                        Rong Li   Robust cell polarity is a dynamic state
                                  established by coupling transport and
                                  GTPase signaling . . . . . . . . . . . . 889
          Dominic M. Clarke and   
           Michael C. Brown and   
           David P. LaLonde and   
          Christopher E. Turner   Phosphorylation of actopaxin regulates
                                  cell spreading and migration . . . . . . 901
              Tadayuki Yago and   
                 Jianhua Wu and   
               C. Diana Wey and   
      Arkadiusz G. Klopocki and   
                  Cheng Zhu and   
               Rodger P. McEver   Catch bonds govern adhesion through
                                  L-selectin at threshold shear  . . . . . 913
              Nicole LeBrasseur   Best stiffness for striation . . . . . . ??
              Nicole LeBrasseur   A model of cell death  . . . . . . . . . ??
              Nicole LeBrasseur   Hitched genes still independent  . . . . ??
              Nicole LeBrasseur   Forced to bond . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Condensation by folding  . . . . . . . . ??
               William A. Wells   Structure with a light touch . . . . . . ??
               William A. Wells   Tumors need less regulation  . . . . . . ??
               William A. Wells   Dystrophic muscles get overexcited . . . ??
               William A. Wells   Slow but steady wins the drug race . . . ??
               William A. Wells   Clathrin starts off alone  . . . . . . . ??
      Said Hashemolhosseini and   
                 Michael Wegner   Impacts of a new transcription factor
                                  family . . . . . . . . . . . . . . . . . 765
             Ross E. Dalbey and   
                   Andreas Kuhn   YidC family members are involved in the
                                  membrane insertion, lateral integration,
                                  folding, and assembly of membrane
                                  proteins . . . . . . . . . . . . . . . . 769
              Nicole LeBrasseur   Correction . . . . . . . . . . . . . . . 925

Journal of Cell Biology
Volume 166, Number 7, September, 2004

            Takao Setoguchi and   
                     Toru Kondo   Nuclear export of OLIG2 in neural stem
                                  cells is essential for ciliary
                                  neurotrophic factor--induced astrocyte
                                  differentiation  . . . . . . . . . . . . 963
              Silke Wissing and   
             Paula Ludovico and   
                 Eva Herker and   
       Sabrina Büttner and   
       Silvia M. Engelhardt and   
            Thorsten Decker and   
             Alexander Link and   
             Astrid Proksch and   
         Fernando Rodrigues and   
         Manuela Corte-Real and   
      Kai-Uwe Fröhlich and   
              Joachim Manns and   
 Céline Candé and   
         Stephan J. Sigrist and   
              Guido Kroemer and   
                    Frank Madeo   An AIF orthologue regulates apoptosis in
                                  yeast  . . . . . . . . . . . . . . . . . 969
              Chiemi Miyagi and   
           Susumu Yamashita and   
                Yusuke Ohba and   
        Hisayoshi Yoshizaki and   
          Michiyuki Matsuda and   
                  Toshio Hirano   STAT3 noncell-autonomously controls
                                  planar cell polarity during zebrafish
                                  convergence and extension  . . . . . . . 975
       Sandra Lacas-Gervais and   
                    Jun Guo and   
            Nicola Strenzke and   
              Eric Scarfone and   
              Melanie Kolpe and   
              Monika Jahkel and   
          Pietro De Camilli and   
               Tobias Moser and   
         Matthew N. Rasband and   
               Michele Solimena   $ \beta $IV$ \sigma $1 spectrin
                                  stabilizes the nodes of Ranvier and axon
                                  initial segments . . . . . . . . . . . . 983
               James Powers and   
              Debra J. Rose and   
              Adam Saunders and   
        Steven Dunkelbarger and   
               Susan Strome and   
              William M. Saxton   Loss of KLP-19 polar ejection force
                                  causes misorientation and missegregation
                                  of holocentric chromosomes . . . . . . . 991
          Gideon Lansbergen and   
             Yulia Komarova and   
              Mauro Modesti and   
               Claire Wyman and   
       Casper C. Hoogenraad and   
           Holly V. Goodson and   
   Régis P. Lemaitre and   
          David N. Drechsel and   
           Erik van Munster and   
    Theodorus W. J. Gadella and   
             Frank Grosveld and   
              Niels Galjart and   
             Gary G. Borisy and   
                 Anna Akhmanova   Conformational changes in CLIP-170
                                  regulate its binding to microtubules and
                                  dynactin localization  . . . . . . . . . 1003
             David Stan\vek and   
            Karla M. Neugebauer   Detection of snRNP assembly
                                  intermediates in Cajal bodies by
                                  fluorescence resonance energy transfer   1015
          Mariusz Karbowski and   
            Seon-Yong Jeong and   
               Richard J. Youle   Endophilin B1 is required for the
                                  maintenance of mitochondrial morphology  1027
              Cary Esselens and   
             Viola Oorschot and   
               Veerle Baert and   
             Tim Raemaekers and   
             Kurt Spittaels and   
          Lutgarde Serneels and   
                  Hui Zheng and   
                Paul Saftig and   
           Bart De Strooper and   
          Judith Klumperman and   
                    Wim Annaert   Presenilin 1 mediates the turnover of
                                  telencephalin in hippocampal neurons via
                                  an autophagic degradative pathway  . . . 1041
             Paola Fabrizio and   
          Luisa Battistella and   
         Raffaello Vardavas and   
          Cristina Gattazzo and   
             Lee-Loung Liou and   
            Alberto Diaspro and   
            Janis W. Dossen and   
        Edith Butler Gralla and   
                Valter D. Longo   Superoxide is a mediator of an
                                  altruistic aging program in
                                  \bionameSaccharomyces cerevisiae . . . . 1055
           Keisuke Kamimura and   
             John M. Rhodes and   
                   Ryu Ueda and   
            Melissa McNeely and   
              Deepak Shukla and   
                Koji Kimata and   
          Patricia G. Spear and   
        Nicholas W. Shworak and   
                 Hiroshi Nakato   Regulation of Notch signaling by
                                  \bionameDrosophila heparan sulfate 3- O
                                  sulfotransferase . . . . . . . . . . . . 1069
        Richard S. Peterson and   
            Roma A. Andhare and   
        Kathleen T. Rousche and   
             Warren Knudson and   
                Weihua Wang and   
         Jami B. Grossfield and   
          Raymond O. Thomas and   
    Robert E. Hollingsworth and   
              Cheryl B. Knudson   CD44 modulates Smad1 activation in the
                                  BMP-7 signaling pathway  . . . . . . . . 1081
                Jiro Takito and   
                 Qais Al-Awqati   Conversion of ES cells to columnar
                                  epithelia by hensin and to squamous
                                  epithelia by laminin . . . . . . . . . . 1093
              Nicole LeBrasseur   Yeast apoptosis debate continues . . . . ??
              Nicole LeBrasseur   A force for holocentrics to reckon with  ??
              Nicole LeBrasseur   Scaffolds from blood to brain  . . . . . ??
              Nicole LeBrasseur   Narcissistic CLIP-170 also attracts
                                  dynactin . . . . . . . . . . . . . . . . ??
                    Rabiya Tuma   Dendritic cells turn traitorous  . . . . ??
                    Rabiya Tuma   Centrosomes take sides . . . . . . . . . ??
                    Rabiya Tuma   Crouching dragon guards nascent proteins ??
                    Rabiya Tuma   Sgo stabilizes glue and microtubules . . ??
                    Rabiya Tuma   Astrocytes orchestrate neuronal
                                  synchrony  . . . . . . . . . . . . . . . ??
            Julie C. Canman and   
               William A. Wells   Rappaport Furrows on Our Minds . . . . . 943
            Oliver J. Gruss and   
                Isabelle Vernos   The mechanism of spindle assembly  . . . 949
          Guillaume Bompard and   
               Emmanuelle Caron   Regulation of WASP/WAVE proteins . . . . 957


Journal of Cell Biology
Volume 167, Number 1, October, 2004

               Phoebe D. Lu and   
         Heather P. Harding and   
                      David Ron   Translation reinitiation at alternative
                                  open reading frames regulates gene
                                  expression in an integrated stress
                                  response . . . . . . . . . . . . . . . . 27
          Rungtawan Sriburi and   
          Suzanne Jackowski and   
             Kazutoshi Mori and   
               Joseph W. Brewer   Xbp1 . . . . . . . . . . . . . . . . . . 35
         Jennifer R. Morgan and   
           Gilbert Di Paolo and   
               Hauke Werner and   
    Valentina A. Shchedrina and   
               Marc Pypaert and   
       Vincent A. Pieribone and   
              Pietro De Camilli   A role for talin in presynaptic function 43
           Paula A. Bubulya and   
  Kannanganattu V. Prasanth and   
         Thomas J. Deerinck and   
             Daniel Gerlich and   
             Joel Beaudouin and   
           Mark H. Ellisman and   
              Jan Ellenberg and   
               David L. Spector   Hypophosphorylated SR splicing factors
                                  transiently localize around active
                                  nucleolar organizing regions in
                                  telophase daughter nuclei  . . . . . . . 51
              Xiaodong Wang and   
            Jeanne Matteson and   
                      Yu An and   
                Bryan Moyer and   
                Jin-San Yoo and   
             Sergei Bannykh and   
              Ian A. Wilson and   
            John R. Riordan and   
               William E. Balch   COPII-dependent export of cystic
                                  fibrosis transmembrane conductance
                                  regulator from the ER uses a di-acidic
                                  exit code  . . . . . . . . . . . . . . . 65
           Brenton L. Scott and   
       Jeffrey S. Van Komen and   
              Hassan Irshad and   
                   Song Liu and   
          Kirilee A. Wilson and   
                 James A. McNew   Sec1p directly stimulates SNARE-mediated
                                  membrane fusion in vitro . . . . . . . . 75
       Rebecca L. Frederick and   
       J. Michael McCaffery and   
         Kyle W. Cunningham and   
               Koji Okamoto and   
                  Janet M. Shaw   Yeast Miro GTPase, Gem1p, regulates
                                  mitochondrial morphology via a novel
                                  pathway  . . . . . . . . . . . . . . . . 87
        Eva-Maria Mandelkow and   
                 Edda Thies and   
          Bernhard Trinczek and   
              Jacek Biernat and   
               Eckard Mandelkow   MARK\slash PAR1 kinase is a regulator of
                                  microtubule-dependent transport in axons 99
          William T. Arthur and   
       Lawrence A. Quilliam and   
             Jonathan A. Cooper   Rap1 promotes cell spreading by
                                  localizing Rac guanine nucleotide
                                  exchange factors . . . . . . . . . . . . 111
                 Katri Koli and   
                Frank Wempe and   
          Anja Sterner-Kock and   
               Anna Kantola and   
              Martina Komor and   
            Wolf-K. Hofmann and   
        Harald von Melchner and   
                Jorma Keski-Oja   Disruption of LTBP-4 function reduces
                                  TGF-$ \beta $ activation and enhances
                                  BMP-4 signaling in the lung  . . . . . . 123
          Tony J. C. Harris and   
                    Mark Peifer   Adherens junction-dependent and
                                  -independent steps in the establishment
                                  of epithelial cell polarity in
                                  \bionameDrosophila . . . . . . . . . . . 135
         Katja S. Grossmann and   
            Christine Grund and   
             Joerg Huelsken and   
             Martin Behrend and   
            Bettina Erdmann and   
           Werner W. Franke and   
              Walter Birchmeier   Requirement of plakophilin 2 for heart
                                  morphogenesis and cardiac junction
                                  formation  . . . . . . . . . . . . . . . 149
                  Chun Chen and   
          Bradford A. Young and   
       Catherine S. Coleman and   
            Anthony E. Pegg and   
                  Dean Sheppard   Spermidine\slash spermine
                                  N$^1$-acetyltransferase specifically
                                  binds to the integrin $ \alpha $9
                                  subunit cytoplasmic domain and enhances
                                  cell migration . . . . . . . . . . . . . 161
      DeannaLee M. Beauvais and   
         Brandon J. Burbach and   
              Alan C. Rapraeger   The syndecan-1 ectodomain regulates $
                                  \alpha_v \beta_3 $ integrin activity in
                                  human mammary carcinoma cells  . . . . . 171
              Nicole LeBrasseur   Splicing takes a NAP . . . . . . . . . . ??
              Nicole LeBrasseur   Export in cystic fibrosis  . . . . . . . ??
              Nicole LeBrasseur   Talin for presynaptic endocytosis  . . . ??
              Nicole LeBrasseur   MARK clears MAP-muddled traffic  . . . . ??
              Nicole LeBrasseur   Polarity precedes adhesion . . . . . . . ??
               William A. Wells   Rewiring the cell  . . . . . . . . . . . ??
               William A. Wells   Polarization by migration  . . . . . . . ??
               William A. Wells   Flow to the front  . . . . . . . . . . . ??
               William A. Wells   Immune synapses make a choice  . . . . . ??
               William A. Wells   Endocytosis gets squeezed  . . . . . . . ??
                    Ira Mellman   Another evolutionary step for the JCB    17
        Carolyn J. Lawrence and   
              R. Kelly Dawe and   
          Karen R. Christie and   
           Don W. Cleveland and   
            Scott C. Dawson and   
            Sharyn A. Endow and   
   Lawrence S. B. Goldstein and   
           Holly V. Goodson and   
          Nobutaka Hirokawa and   
            Jonathon Howard and   
        Russell L. Malmberg and   
        J. Richard McIntosh and   
              Harukata Miki and   
       Timothy J. Mitchison and   
              Yasushi Okada and   
       Anireddy S. N. Reddy and   
          William M. Saxton and   
            Manfred Schliwa and   
        Jonathan M. Scholey and   
             Ronald D. Vale and   
          Claire E. Walczak and   
                 Linda Wordeman   A standardized kinesin nomenclature  . . 19
                  David Ron and   
            Randolph Y. Hampton   Membrane biogenesis and the unfolded
                                  protein response . . . . . . . . . . . . 23

Journal of Cell Biology
Volume 167, Number 2, October, 2004

                    Rabiya Tuma   Vesicle biogenesis potentiation  . . . . ??
                    Rabiya Tuma   One protein, two pools . . . . . . . . . ??
                    Rabiya Tuma   One cyclin for adult neurogenesis  . . . ??
                    Rabiya Tuma   Tugging and pulling in asymmetric cell
                                  divisions  . . . . . . . . . . . . . . . ??
                    Rabiya Tuma   Slipping through the middle  . . . . . . ??
              Nicole LeBrasseur   A chaperone feels the heat . . . . . . . ??
              Nicole LeBrasseur   Cells have a bubbly look . . . . . . . . ??
              Nicole LeBrasseur   Uncooperative immune cells . . . . . . . ??
              Nicole LeBrasseur   VASP comet sightings . . . . . . . . . . ??
              Nicole LeBrasseur   Insulin keeps time . . . . . . . . . . . ??
               Dan Lindholm and   
              Urmas Arumäe   Cell differentiation . . . . . . . . . . 193
                 Uwe Vinkemeier   Getting the message across, STAT! Design
                                  principles of a molecular signaling
                                  circuit  . . . . . . . . . . . . . . . . 197
              Atsuko Kodama and   
              Terry Lechler and   
                   Elaine Fuchs   Coordinating cytoskeletal tracks to
                                  polarize cellular movements  . . . . . . 203
             Anna Kowalczyk and   
      Robert K. Filipkowski and   
              Marcin Rylski and   
     Grzegorz M. Wilczynski and   
         Filip A. Konopacki and   
             Jacek Jaworski and   
         Maria A. Ciemerych and   
             Piotr Sicinski and   
               Leszek Kaczmarek   The critical role of cyclin D2 in adult
                                  neurogenesis . . . . . . . . . . . . . . 209
             Salvatore Pece and   
            Michela Serresi and   
            Elisa Santolini and   
                Maria Capra and   
            Esther Hulleman and   
         Viviana Galimberti and   
            Stefano Zurrida and   
        Patrick Maisonneuve and   
             Giuseppe Viale and   
            Pier Paolo Di Fiore   Loss of negative regulation by Numb over
                                  Notch is relevant to human breast
                                  carcinogenesis . . . . . . . . . . . . . 215
                  Sara Weis and   
                Jianhua Cui and   
                 Leo Barnes and   
                  David Cheresh   Endothelial barrier disruption by
                                  VEGF-mediated Src activity potentiates
                                  tumor cell extravasation and metastasis  223
         Stephen M. Huisman and   
         Olivia A. M. Bales and   
             Marie Bertrand and   
    Monique F. M. A. Smeets and   
             Steven I. Reed and   
                   Marisa Segal   Differential contribution of Bud6p and
                                  Kar9p to microtubule capture and spindle
                                  orientation in S. cerevisiae . . . . . . 231
   Jean-Claude Labbé and   
           Erin K. McCarthy and   
                  Bob Goldstein   The forces that position a mitotic
                                  spindle asymmetrically are tethered
                                  until after the time of spindle assembly 245
          Amanda K. Wiggins and   
               Guangwei Wei and   
        Epaminondas Doxakis and   
                Connie Wong and   
                Amy A. Tang and   
                Keling Zang and   
              Esther J. Luo and   
            Rachael L. Neve and   
         Louis F. Reichardt and   
                  Eric J. Huang   Interaction of Brn3a and HIPK2 mediates
                                  transcriptional repression of sensory
                                  neuron survival  . . . . . . . . . . . . 257
                   Rose Tam and   
             Kelly P. Smith and   
             Jeanne B. Lawrence   The 4q subtelomere harboring the FSHD
                                  locus is specifically anchored with
                                  peripheral heterochromatin unlike most
                                  human telomeres  . . . . . . . . . . . . 269
       Alison K. Gillingham and   
           Amy Hin Yan Tong and   
              Charles Boone and   
                     Sean Munro   The GTPase Arf1p and the ER to Golgi
                                  cargo receptor Erv14p cooperate to
                                  recruit the golgin Rud3p to the
                                  cis-Golgi  . . . . . . . . . . . . . . . 281
             Fubito Nakatsu and   
             Motohiro Okada and   
               Fumiaki Mori and   
            Noriko Kumazawa and   
               Hiroto Iwasa and   
                   Gang Zhu and   
            Yasufumi Kasagi and   
            Haruyuki Kamiya and   
             Akihiro Harada and   
         Kazuhiro Nishimura and   
             Arata Takeuchi and   
           Taisuke Miyazaki and   
          Masahiko Watanabe and   
              Shigeki Yuasa and   
             Toshiya Manabe and   
         Koichi Wakabayashi and   
               Sunao Kaneko and   
              Takashi Saito and   
                   Hiroshi Ohno   Defective function of GABA-containing
                                  synaptic vesicles in mice lacking the
                                  AP-3B clathrin adaptor . . . . . . . . . 293
            Kevin M. Wright and   
         Michael W. Linhoff and   
         Patrick Ryan Potts and   
              Mohanish Deshmukh   Decreased apoptosome activity with
                                  neuronal differentiation sets the
                                  threshold for strict IAP regulation of
                                  apoptosis  . . . . . . . . . . . . . . . 303
               Matthew Lord and   
              Thomas D. Pollard   UCS protein Rng3p activates actin
                                  filament gliding by fission yeast
                                  myosin--II . . . . . . . . . . . . . . . 315
              Jong-Hwan Lee and   
             Tomoya Katakai and   
              Takahiro Hara and   
             Hiroyuki Gonda and   
               Manabu Sugai and   
                  Akira Shimizu   Roles of p--ERM and Rho--ROCK signaling
                                  in lymphocyte polarity and uropod
                                  formation  . . . . . . . . . . . . . . . 327
           Cara J. Gottardi and   
              Barry M. Gumbiner   Distinct molecular forms of $ \beta
                                  $-catenin are targeted to adhesive or
                                  transcriptional complexes  . . . . . . . 339
         Katsuhisa Matsuura and   
               Hiroshi Wada and   
               Toshio Nagai and   
           Yoshihiro Iijima and   
             Tohru Minamino and   
              Masanori Sano and   
            Hiroshi Akazawa and   
       Jeffery D. Molkentin and   
           Hiroshi Kasanuki and   
                   Issei Komuro   Cardiomyocytes fuse with surrounding
                                  noncardiomyocytes and reenter the cell
                                  cycle  . . . . . . . . . . . . . . . . . 351
            Holly Colognato and   
     Shwetha Ramachandrappa and   
             Inger M. Olsen and   
       Charles ffrench-Constant   Integrins direct Src family kinases to
                                  regulate distinct phases of
                                  oligodendrocyte development  . . . . . . 365
      Christopher V. Carman and   
            Timothy A. Springer   A transmigratory cup in leukocyte
                                  diapedesis both through individual
                                  vascular endothelial cells and between
                                  them . . . . . . . . . . . . . . . . . . 377

Journal of Cell Biology
Volume 167, Number 3, November, 2004

              Nicole LeBrasseur   Escorting STAT5A . . . . . . . . . . . . ??
              Nicole LeBrasseur   Expaaaaanded inclusions  . . . . . . . . ??
              Nicole LeBrasseur   Patches ride cables  . . . . . . . . . . ??
              Nicole LeBrasseur   Speed from recycling . . . . . . . . . . ??
              Nicole LeBrasseur   Wounds quiet basal cells . . . . . . . . ??
               William A. Wells   Signaling together apart . . . . . . . . ??
               William A. Wells   Dormant tumors awaken  . . . . . . . . . ??
               William A. Wells   Neurons inch along . . . . . . . . . . . ??
               William A. Wells   Diabetes as a stress response  . . . . . ??
               William A. Wells   A SNARE for fast endocytosis . . . . . . ??
             Brendan D. Manning   Balancing Akt with S6K . . . . . . . . . 399
            Loretta Dorstyn and   
              Kathryn Mills and   
              Yuri Lazebnik and   
                   Sharad Kumar   The two cytochrome c species, DC3 and
                                  DC4, are not required for caspase
                                  activation and apoptosis in
                                  \bionameDrosophila cells . . . . . . . . 405
          Ilya M. Nasrallah and   
         Jeremy C. Minarcik and   
              Jeffrey A. Golden   A polyalanine tract expansion in Arx
                                  forms intranuclear inclusions and
                                  results in increased cell death  . . . . 411
             Grazia Camarda and   
            Francesca Siepi and   
          Deborah Pajalunga and   
         Camilla Bernardini and   
             Rossella Rossi and   
      Alessandra Montecucco and   
              Ettore Meccia and   
                Marco Crescenzi   A pRb-independent mechanism preserves
                                  the postmitotic state in terminally
                                  differentiated skeletal muscle cells . . 417
             Emad I. Khater and   
           Robert E. Sinden and   
            Johannes T. Dessens   A malaria membrane skeletal protein is
                                  essential for normal morphogenesis,
                                  motility, and infectivity of sporozoites 425
           Lilia Alberghina and   
          Riccardo L. Rossi and   
             Lorenzo Querin and   
              Valeria Wanke and   
                   Marco Vanoni   A cell sizer network involving Cln3 and
                                  Far1 controls entrance into S phase in
                                  the mitotic cycle of budding yeast . . . 433
               Yukio Kimata and   
             Daisuke Oikawa and   
             Yusuke Shimizu and   
       Yuki Ishiwata-Kimata and   
                    Kenji Kohno   A role for BiP as an adjustor for the
                                  endoplasmic reticulum stress-sensing
                                  protein Ire1 . . . . . . . . . . . . . . 445
        Julián Pardo and   
             Alberto Bosque and   
                Reina Brehm and   
           Reinhard Wallich and   
               Javier Naval and   
       Arno Müllbacher and   
               Alberto Anel and   
                Markus M. Simon   Apoptotic pathways are selectively
                                  activated by granzyme A and/or granzyme
                                  B in CTL-mediated target cell lysis  . . 457
    Christopher C. Williams and   
            June G. Allison and   
           Gregory A. Vidal and   
           Matthew E. Burow and   
         Barbara S. Beckman and   
               Luis Marrero and   
                 Frank E. Jones   The ERBB4/HER4 receptor tyrosine kinase
                                  regulates gene expression by functioning
                                  as a STAT5A nuclear chaperone  . . . . . 469
                 Carme Sole and   
              Xavier Dolcet and   
           Miguel F. Segura and   
         Humberto Gutierrez and   
     Maria-Teresa Diaz-Meco and   
        Raffaella Gozzelino and   
             Daniel Sanchis and   
           Jose R. Bayascas and   
              Carme Gallego and   
               Jorge Moscat and   
             Alun M. Davies and   
                Joan X. Comella   The death receptor antagonist FAIM
                                  promotes neurite outgrowth by a
                                  mechanism that depends on ERK and NF-$
                                  \kappa $B signaling  . . . . . . . . . . 479
              Jong-Sun Kang and   
               Min-Jeong Yi and   
                  Wei Zhang and   
        Jessica L. Feinleib and   
             Francesca Cole and   
               Robert S. Krauss   Netrins and neogenin promote myotube
                                  formation  . . . . . . . . . . . . . . . 493
            Atsuo T. Sasaki and   
                Cheryl Chun and   
              Kosuke Takeda and   
              Richard A. Firtel   Localized Ras signaling at the leading
                                  edge regulates PI3K, cell polarity, and
                                  directional cell movement  . . . . . . . 505
          Thomas M. Huckaba and   
              Anna Card Gay and   
    Luiz Fernando Pantalena and   
          Hyeong-Cheol Yang and   
                    Liza A. Pon   Live cell imaging of the assembly,
                                  disassembly, and actin cable-dependent
                                  movement of endosomes and actin patches
                                  in the budding yeast,
                                  \bionameSaccharomyces cerevisiae . . . . 519
              Agnes Lee Ang and   
           Tomohiko Taguchi and   
            Stephen Francis and   
          Heike Fölsch and   
        Lindsay J. Murrells and   
               Marc Pypaert and   
              Graham Warren and   
                    Ira Mellman   Recycling endosomes can serve as
                                  intermediates during transport from the
                                  Golgi to the plasma membrane of MDCK
                                  cells  . . . . . . . . . . . . . . . . . 531
         Lauren R. Strachan and   
              Maureen L. Condic   Cranial neural crest recycle surface
                                  integrins in a substratum-dependent
                                  manner to promote rapid motility . . . . 545
        Theresa S. Richards and   
           Clarence A. Dunn and   
          William G. Carter and   
             Marcia L. Usui and   
             John E. Olerud and   
                  Paul D. Lampe   Protein kinase C spatially and
                                  temporally regulates gap junctional
                                  communication during human wound repair
                                  via phosphorylation of connexin43 on
                                  serine368  . . . . . . . . . . . . . . . 555
          Neetu Gupta-Rossi and   
             Emmanuelle Six and   
               Odile LeBail and   
Frédérique Logeat and   
        Patricia Chastagner and   
                 Annie Olry and   
          Alain Israël and   
                  Christel Brou   Correction . . . . . . . . . . . . . . . 563
              Hira Lal Goel and   
               Mara Fornaro and   
              Loredana Moro and   
             Natalia Teider and   
              Johng S. Rhim and   
               Michael King and   
              Lucia R. Languino   Correction . . . . . . . . . . . . . . . 565
              Xiaodong Wang and   
            Jeanne Matteson and   
                      Yu An and   
                Bryan Moyer and   
                Jin-San Yoo and   
             Sergei Bannykh and   
              Ian A. Wilson and   
            John R. Riordan and   
               William E. Balch   Correction . . . . . . . . . . . . . . . 567

Journal of Cell Biology
Volume 167, Number 4, November, 2004

                    Rabiya Tuma   Mitochondria move in on calcium  . . . . ??
                    Rabiya Tuma   ES cells without teratomas . . . . . . . ??
                    Rabiya Tuma   Transport if loaded  . . . . . . . . . . ??
                    Rabiya Tuma   Invadolysin opens many doors . . . . . . ??
                    Rabiya Tuma   Making a raft with oligomers . . . . . . ??
              Nicole LeBrasseur   Palindromic protection . . . . . . . . . ??
              Nicole LeBrasseur   SOS needs help getting active  . . . . . ??
              Nicole LeBrasseur   SNX1 hugs the curves . . . . . . . . . . ??
              Nicole LeBrasseur   GTPase modes modeled . . . . . . . . . . ??
              Nicole LeBrasseur   Profilin for processivity  . . . . . . . ??
              Bryan Zeitler and   
                   Karsten Weis   The FG-repeat asymmetry of the nuclear
                                  pore complex is dispensable for bulk
                                  nucleocytoplasmic transport in vivo  . . 583
               Ian C. Berke and   
             Thomas Boehmer and   
         Günter Blobel and   
             Thomas U. Schwartz   Structural and functional analysis of
                                  Nup133 domains reveals modular building
                                  blocks of the nuclear pore complex . . . 591
               Devi M. Nair and   
           P. Edward Purdue and   
                Paul B. Lazarow   Pex7p translocates in and out of
                                  peroxisomes in \bionameSaccharomyces
                                  cerevisiae . . . . . . . . . . . . . . . 599
               Xiaolan Zhao and   
               Chia-Yung Wu and   
             Günter Blobel   Mlp-dependent anchorage and
                                  stabilization of a desumoylating enzyme
                                  is required to prevent clonal lethality  605
            Raymond C. Chan and   
          Aaron F. Severson and   
               Barbara J. Meyer   Condensin restructures chromosomes in
                                  preparation for meiotic divisions  . . . 613
             Silvia Espejel and   
                Peter Klatt and   
Josiane Ménissier-de Murcia and   
Juan Martín-Caballero and   
            Juana M. Flores and   
         Guillermo Taccioli and   
          Gilbert de Murcia and   
         María A. Blasco   Impact of telomerase ablation on
                                  organismal viability, aging, and
                                  tumorigenesis in mice lacking the DNA
                                  repair proteins PARP-1, Ku86, or
                                  DNA--PKcs  . . . . . . . . . . . . . . . 627
            Akwasi Anyanful and   
                 Kanako Ono and   
          Robert C. Johnsen and   
                    Hinh Ly and   
              Victor Jensen and   
           David L. Baillie and   
                  Shoichiro Ono   The RNA-binding protein SUP-12 controls
                                  muscle-specific splicing of the
                                  ADF/cofilin pre-mRNA in \bionameC.
                                  elegans  . . . . . . . . . . . . . . . . 639
           Scott M. Plafker and   
          Kendra S. Plafker and   
          Allan M. Weissman and   
                  Ian G. Macara   Ubiquitin charging of human class III
                                  ubiquitin-conjugating enzymes triggers
                                  their nuclear import . . . . . . . . . . 649
                  Muqing Yi and   
               David Weaver and   
   György Hajnóczky   Control of mitochondrial motility and
                                  distribution by the calcium signal . . . 661
               Brian McHugh and   
              Sue A. Krause and   
                     Bin Yu and   
           Anne-Marie Deans and   
              Sarah Heasman and   
            Paul McLaughlin and   
           Margarete M. S. Heck   Invadolysin  . . . . . . . . . . . . . . 673
              Mayya Meriane and   
         Joseph Tcherkezian and   
        Christine A. Webber and   
              Eric I. Danek and   
             Ibtissem Triki and   
            Sarah McFarlane and   
      Evelyne Bloch-Gallego and   
         Nathalie Lamarche-Vane   Phosphorylation of DCC by Fyn mediates
                                  Netrin-1 signaling in growth cone
                                  guidance . . . . . . . . . . . . . . . . 687
            Simona Paladino and   
          Daniela Sarnataro and   
             Rudolf Pillich and   
             Simona Tivodar and   
               Lucio Nitsch and   
                 Chiara Zurzolo   Protein oligomerization modulates raft
                                  partitioning and apical sorting of
                                  GPI-anchored proteins  . . . . . . . . . 699
          Alessandra Bolino and   
             Annalisa Bolis and   
    Stefano Carlo Previtali and   
               Giorgia Dina and   
             Simona Bussini and   
              Gabriele Dati and   
             Stefano Amadio and   
           Ubaldo Del Carro and   
            Dolores D. Mruk and   
         Maria Laura Feltri and   
               C. Yan Cheng and   
           Angelo Quattrini and   
               Lawrence Wrabetz   Disruption of Mtmr2 produces CMT4B1-like
                                  neuropathy with myelin outfolding and
                                  impaired spermatogenesis . . . . . . . . 711
           Erhard Bieberich and   
                Jeane Silva and   
               Guanghu Wang and   
       Kannan Krishnamurthy and   
                Brian G. Condie   Selective apoptosis of pluripotent mouse
                                  and human stem cells by novel ceramide
                                  analogues prevents teratoma formation
                                  and enriches for neural precursors in ES
                                  cell--derived neural transplants . . . . 723
          Richard M. Siegel and   
           Jagan R. Muppidi and   
            Malabika Sarker and   
              Adrian Lobito and   
                Melinda Jen and   
               David Martin and   
          Stephen E. Straus and   
             Michael J. Lenardo   Spots  . . . . . . . . . . . . . . . . . 735
                 Wenjie Bao and   
         Staffan Strömblad   Integrin $ \alpha $v-mediated
                                  inactivation of p53 controls a
                                  MEK1-dependent melanoma cell survival
                                  pathway in three-dimensional collagen    745
               Tae-Hwa Chun and   
              Farideh Sabeh and   
                 Ichiro Ota and   
              Hedwig Murphy and   
          Kevin T. McDonagh and   
              Kenn Holmbeck and   
    Henning Birkedal-Hansen and   
            Edward D. Allen and   
               Stephen J. Weiss   MT1-MMP-dependent neovessel formation
                                  within the confines of the
                                  three-dimensional extracellular matrix   757
              Farideh Sabeh and   
                 Ichiro Ota and   
              Kenn Holmbeck and   
    Henning Birkedal-Hansen and   
               Paul Soloway and   
            Milagros Balbin and   
          Carlos Lopez-Otin and   
             Steven Shapiro and   
               Masaki Inada and   
              Stephen Krane and   
               Edward Allen and   
                Duane Chung and   
               Stephen J. Weiss   Tumor cell traffic through the
                                  extracellular matrix is controlled by
                                  the membrane-anchored collagenase
                                  MT1-MMP  . . . . . . . . . . . . . . . . 769
                Hongjun Liu and   
  Michelle Mardahl-Dumesnil and   
            Sean T. Sweeney and   
            Cahir J. O'Kane and   
           Sanford I. Bernstein   Retraction . . . . . . . . . . . . . . . 783
                   Alan W. Dove   Retraction . . . . . . . . . . . . . . . 785

Journal of Cell Biology
Volume 167, Number 5, December, 2004

              Nicole LeBrasseur   Ameloblastin . . . . . . . . . . . . . . ??
              Nicole LeBrasseur   Telomeric spindle proteins . . . . . . . ??
              Nicole LeBrasseur   Death DNase tied down  . . . . . . . . . ??
              Nicole LeBrasseur   Cholesterol prevents Alzheimer's . . . . ??
              Nicole LeBrasseur   Quick results for thyroid hormone  . . . ??
               William A. Wells   Elimination by shedding  . . . . . . . . ??
               William A. Wells   Rocking on Pins  . . . . . . . . . . . . ??
               William A. Wells   Destroy and localize . . . . . . . . . . ??
               William A. Wells   Bacteria diversify . . . . . . . . . . . ??
               William A. Wells   Picking the clathrin lock  . . . . . . . ??
          Christoph Kaether and   
                Christian Haass   A lipid boundary separates APP and
                                  secretases and limits amyloid $ \beta
                                  $-peptide generation . . . . . . . . . . 809
          David T. Miyamoto and   
         Zachary E. Perlman and   
          Kendra S. Burbank and   
             Aaron C. Groen and   
           Timothy J. Mitchison   The kinesin Eg5 drives poleward
                                  microtubule flux in \bionameXenopus
                                  laevis egg extract spindles  . . . . . . 813
                  Lifeng Xu and   
         Elizabeth H. Blackburn   Human Rif1 protein binds aberrant
                                  telomeres and aligns along anaphase
                                  midzone microtubules . . . . . . . . . . 819
              Helder Maiato and   
            Conly L. Rieder and   
               Alexey Khodjakov   Kinetochore-driven formation of
                                  kinetochore fibers contributes to
                                  spindle assembly during animal mitosis   831
               Ayumi Yamada and   
                 Brad Duffy and   
          Jennifer A. Perry and   
                Sally Kornbluth   DNA replication checkpoint control of
                                  Wee1 stability by vertebrate Hsl7  . . . 841
        Delphine Lechardeur and   
                    Ming Xu and   
              Gergely L. Lukacs   Contrasting nuclear dynamics of the
                                  caspase-activated DNase (CAD) in
                                  dividing and apoptotic cells . . . . . . 851
            Juliette Jouhet and   
       Eric Maréchal and   
             Barbara Baldan and   
             Richard Bligny and   
             Jacques Joyard and   
                Maryse A. Block   Phosphate deprivation induces transfer
                                  of DGDG galactolipid from chloroplast to
                                  mitochondria . . . . . . . . . . . . . . 863
         Andreas Wiederkehr and   
       Johan-Owen De Craene and   
         Susan Ferro-Novick and   
                   Peter Novick   Functional specialization within a
                                  vesicle tethering complex  . . . . . . . 875
               Charles Boyd and   
                Thom Hughes and   
               Marc Pypaert and   
                   Peter Novick   Vesicles carry most exocyst subunits to
                                  exocytic sites marked by the remaining
                                  two subunits, Sec3p and Exo70p . . . . . 889
          Jeremiah F. Roeth and   
              Maya Williams and   
          Matthew R. Kasper and   
           Tracey M. Filzen and   
            Kathleen L. Collins   HIV-1 Nef disrupts MHC--I trafficking by
                                  recruiting AP-1 to the MHC--I
                                  cytoplasmic tail . . . . . . . . . . . . 903
            Nuttawut Saelim and   
               Linu M. John and   
                     Jun Wu and   
            Jeong Soon Park and   
                 Yidong Bai and   
           Patricia Camacho and   
            James D. Lechleiter   Nontranscriptional modulation of
                                  intracellular Ca$^{2+}$ signaling by
                                  ligand stimulated thyroid hormone
                                  receptor . . . . . . . . . . . . . . . . 915
            David M. Thomas and   
          Sandra A. Johnson and   
            Natalie A. Sims and   
         Melanie K. Trivett and   
             John L. Slavin and   
             Brian P. Rubin and   
                Paul Waring and   
          Grant A. McArthur and   
            Carl R. Walkley and   
         Andrew J. Holloway and   
           Dileepa Diyagama and   
           Jonathon E. Grim and   
           Bruce E. Clurman and   
        David D. L. Bowtell and   
               Jong-Seo Lee and   
       Gabriel M. Gutierrez and   
          Denise M. Piscopo and   
           Shannon A. Carty and   
                Philip W. Hinds   Terminal osteoblast differentiation,
                                  mediated by runx2 and p27 $^{\rm KIP1}$,
                                  is disrupted in osteosarcoma . . . . . . 925
        Michail S. Davidoff and   
           Ralf Middendorff and   
         Grigori Enikolopov and   
         Dieter Riethmacher and   
          Adolf F. Holstein and   
             Dieter Müller   Progenitor cells of the
                                  testosterone-producing Leydig cells
                                  revealed . . . . . . . . . . . . . . . . 935
             Gunnar Schuetz and   
       Marta Rosário and   
                  Jan Grimm and   
         Tobias M. Boeckers and   
     Eckart D. Gundelfinger and   
              Walter Birchmeier   The neuronal scaffold protein Shank3
                                  mediates signaling and biological
                                  function of the receptor tyrosine kinase
                                  Ret in epithelial cells  . . . . . . . . 945
        Jose Abad-Rodriguez and   
      Maria Dolores Ledesma and   
        Katleen Craessaerts and   
               Simona Perga and   
              Miguel Medina and   
           Andre Delacourte and   
             Colin Dingwall and   
           Bart De Strooper and   
                Carlos G. Dotti   Neuronal membrane cholesterol loss
                                  enhances amyloid peptide generation  . . 953
                 Ko Okamura and   
            Hidekazu Tanaka and   
             Yoshiki Yagita and   
            Yoshinaga Saeki and   
            Akihiko Taguchi and   
            Yasushi Hiraoka and   
              Ling-Hui Zeng and   
            David R. Colman and   
                   Naomasa Miki   Cadherin activity is required for
                                  activity-induced spine remodeling  . . . 961
           Satoshi Fukumoto and   
             Takayoshi Kiba and   
              Bradford Hall and   
            Noriyuki Iehara and   
           Takashi Nakamura and   
          Glenn Longenecker and   
          Paul H. Krebsbach and   
              Antonio Nanci and   
          Ashok B. Kulkarni and   
               Yoshihiko Yamada   Ameloblastin is a cell adhesion molecule
                                  required for maintaining the
                                  differentiation state of ameloblasts . . 973
         Katsuhisa Matsuura and   
               Hiroshi Wada and   
               Toshio Nagai and   
           Yoshihiro Iijima and   
             Tohru Minamino and   
              Masanori Sano and   
            Hiroshi Akazawa and   
       Jeffery D. Molkentin and   
           Hiroshi Kasanuki and   
                   Issei Komuro   Correction . . . . . . . . . . . . . . . 985

Journal of Cell Biology
Volume 167, Number 6, December, 2004

                    Rabiya Tuma   Measuring insulin  . . . . . . . . . . . ??
                    Rabiya Tuma   PINCHing together integrins and
                                  signaling  . . . . . . . . . . . . . . . ??
                    Rabiya Tuma   Clustering in integrin binding . . . . . ??
                    Rabiya Tuma   Targeting the inner nuclear membrane . . ??
                    Rabiya Tuma   Stick hard, signal fast  . . . . . . . . ??
              Nicole LeBrasseur   Dynamin in fission and fusion  . . . . . ??
              Nicole LeBrasseur   Opening closed pores . . . . . . . . . . ??
              Nicole LeBrasseur   Insulin breaks hearts  . . . . . . . . . ??
              Nicole LeBrasseur   Time keepers abound  . . . . . . . . . . ??
              Nicole LeBrasseur   Checking in on spindle size  . . . . . . ??
                    Dalu Xu and   
                   Jesse C. Hay   Reconstitution of COPII vesicle fusion
                                  to generate a pre-Golgi intermediate
                                  compartment  . . . . . . . . . . . . . . 997
              Ying Jie Wang and   
                Wen Hong Li and   
                  Jing Wang and   
                      Ke Xu and   
                  Ping Dong and   
                  Xiang Luo and   
                   Helen L. Yin   Critical role of PIP5KI$ \gamma $87 in
                                  InsP$_3$-mediated Ca$^{2+}$ signaling    1005
          Michael M. Kozlov and   
        Alexander D. Bershadsky   Processive capping by formin suggests a
                                  force-driven mechanism of actin
                                  polymerization . . . . . . . . . . . . . 1011
           Julie L. Kadrmas and   
              Mark A. Smith and   
          Kathleen A. Clark and   
       Stephen M. Pronovost and   
              Nemone Muster and   
              John R. Yates and   
               Mary C. Beckerle   The integrin effector PINCH regulates
                                  JNK activity and epithelial migration in
                                  concert with Ras suppressor 1  . . . . . 1019
              Kathrin Plath and   
                Dale Talbot and   
            Karien M. Hamer and   
               Arie P. Otte and   
             Thomas P. Yang and   
            Rudolf Jaenisch and   
                Barbara Panning   Developmentally regulated alterations in
                                  Polycomb repressive complex 1 proteins
                                  on the inactive X chromosome . . . . . . 1025
            Chizuko Tsurumi and   
           Steffen Hoffmann and   
              Stephan Geley and   
              Ralph Graeser and   
              Zbigniew Polanski   The spindle assembly checkpoint is not
                                  essential for CSF arrest of mouse
                                  oocytes  . . . . . . . . . . . . . . . . 1037
              Tomoyuki Ohba and   
           Eric C. Schirmer and   
         Takeharu Nishimoto and   
                   Larry Gerace   Energy- and temperature-dependent
                                  transport of integral proteins to the
                                  inner nuclear membrane via the nuclear
                                  pore . . . . . . . . . . . . . . . . . . 1051
           Mirko Trajkovski and   
              Hassan Mziaut and   
        Anke Altkrüger and   
             Joke Ouwendijk and   
          Klaus-Peter Knoch and   
         Stefan Müller and   
               Michele Solimena   Nuclear translocation of an ICA512
                                  cytosolic fragment couples granule
                                  exocytosis and insulin expression in $
                                  \beta $-cells  . . . . . . . . . . . . . 1063
         J. Michael Younger and   
                Hong-Yu Ren and   
                Liling Chen and   
              Chun-Yang Fan and   
              Andrea Fields and   
              Cam Patterson and   
                 Douglas M. Cyr   A foldable CFTR$ \Delta $F508 biogenic
                                  intermediate accumulates upon inhibition
                                  of the Hsc70--CHIP E3 ubiquitin ligase   1075
          Rutilio A. Fratti and   
               Youngsoo Jun and   
             Alexey J. Merz and   
            Nathan Margolis and   
                William Wickner   Interdependent assembly of specific
                                  regulatory lipids and membrane fusion
                                  proteins into the vertex ring domain of
                                  docked vacuoles  . . . . . . . . . . . . 1087
           Marcello Marelli and   
          Jennifer J. Smith and   
                Sunhee Jung and   
                  Eugene Yi and   
      Alexey I. Nesvizhskii and   
         Rowan H. Christmas and   
           Ramsey A. Saleem and   
             Yuen Yi C. Tam and   
          Andrei Fagarasanu and   
          David R. Goodlett and   
            Ruedi Aebersold and   
     Richard A. Rachubinski and   
              John D. Aitchison   Quantitative mass spectrometry reveals a
                                  role for the GTPase Rho1p in actin
                                  organization on the peroxisome membrane  1099
        Sergei A. Kuznetsov and   
             Mara Riminucci and   
                Navid Ziran and   
           Takeo W. Tsutsui and   
           Alessandro Corsi and   
                Laura Calvi and   
        Henry M. Kronenberg and   
         Ernestina Schipani and   
        Pamela Gehron Robey and   
                   Paolo Bianco   The interplay of osteogenesis and
                                  hematopoiesis  . . . . . . . . . . . . . 1113
               Thierry Brun and   
            Isobel Franklin and   
                Luc St-Onge and   
         Anna Biason-Lauber and   
         Eugene J. Schoenle and   
          Claes B. Wollheim and   
             Benoit R. Gauthier   The diabetes-linked transcription factor
                                  PAX4 promotes $ \beta $-cell
                                  proliferation and survival in rat and
                                  human islets . . . . . . . . . . . . . . 1123
           Jennifer Zeitler and   
             Cynthia P. Hsu and   
             Heather Dionne and   
                   David Bilder   Domains controlling cell polarity and
                                  proliferation in the \bionameDrosophila
                                  tumor suppressor Scribble  . . . . . . . 1137
               Ranjana Arya and   
              Vishram Kedar and   
           Jae Ryoung Hwang and   
            Holly McDonough and   
                 Hui-Hua Li and   
                Joan Taylor and   
                  Cam Patterson   Muscle ring finger protein-1 inhibits
                                  PKC$ \epsilon $ activation and prevents
                                  cardiomyocyte hypertrophy  . . . . . . . 1147
              Andrew Devitt and   
             Kate G. Parker and   
           Carol Anne Ogden and   
              Ceri Oldreive and   
            Michael F. Clay and   
         Lynsey A. Melville and   
     Christopher O. Bellamy and   
          Adam Lacy-Hulbert and   
         Sophie C. Gangloff and   
            Sanna M. Goyert and   
         Christopher D. Gregory   Persistence of apoptotic cells without
                                  autoimmune disease or inflammation in
                                  CD14$^{-/} - $ mice  . . . . . . . . . . 1161
           Elena Goncharova and   
           Dmitry Goncharov and   
              Daniel Noonan and   
              Vera P. Krymskaya   TSC2 modulates actin cytoskeleton and
                                  focal adhesion through TSC1-binding
                                  domain and the Rac1 GTPase . . . . . . . 1171
               Yeh-Shiu Chu and   
          William A. Thomas and   
               Olivier Eder and   
            Frederic Pincet and   
                 Eric Perez and   
           Jean Paul Thiery and   
                  Sylvie Dufour   Force measurements in
                                  E-cadherin-mediated cell doublets reveal
                                  rapid adhesion strengthened by actin
                                  cytoskeleton remodeling through Rac and
                                  Cdc42  . . . . . . . . . . . . . . . . . 1183
            Xiang-Tian Kong and   
             Fang-Ming Deng and   
                    Ping Hu and   
             Feng-Xia Liang and   
                    Ge Zhou and   
           Anna B. Auerbach and   
             Nancy Genieser and   
            Peter K. Nelson and   
           Edith S. Robbins and   
              Ellen Shapiro and   
             Bechara Kachar and   
                  Tung-Tien Sun   Roles of uroplakins in plaque formation,
                                  umbrella cell enlargement, and urinary
                                  tract diseases . . . . . . . . . . . . . 1195
              Shingo Suzuki and   
          Tadahiro Numakawa and   
           Kazuhiro Shimazu and   
        Hisatsugu Koshimizu and   
                Tomoko Hara and   
           Hiroshi Hatanaka and   
                    Lin Mei and   
                     Bai Lu and   
                  Masami Kojima   BDNF-induced recruitment of TrkB
                                  receptor into neuronal lipid rafts . . . 1205
     François Ahimou and   
               Lee-Peng Mok and   
               Boris Bardot and   
                  Cedric Wesley   The adhesion force of Notch with Delta
                                  and the rate of Notch signaling  . . . . 1217
                Xiuwei Yang and   
          Oleg V. Kovalenko and   
                   Wei Tang and   
            Christoph Claas and   
       Christopher S. Stipp and   
               Martin E. Hemler   Palmitoylation supports assembly and
                                  function of integrin--tetraspanin
                                  complexes  . . . . . . . . . . . . . . . 1231
                 Minsoo Kim and   
      Christopher V. Carman and   
                   Wei Yang and   
              Azucena Salas and   
            Timothy A. Springer   The primacy of affinity over clustering
                                  in regulation of adhesiveness of the
                                  integrin $ \alpha $$_L$ $ \beta_2$ . . . 1241
             Brendan D. Manning   Correction . . . . . . . . . . . . . . . 1255


Journal of Cell Biology
Volume 220, Number 5, May 3, 2021

               Zongbing You and   
               Daniel Saims and   
             Shaoqiong Chen and   
            Zhaocheng Zhang and   
         Denis C. Guttridge and   
             Kun-liang Guan and   
       Ormond A. MacDougald and   
        Anthony M. C. Brown and   
                Gerard Evan and   
             Jan Kitajewski and   
                    Cun-Yu Wang   Correction: Wnt signaling promotes
                                  oncogenic transformation by inhibiting
                                  c-Myc-induced apoptosis  . . . . . . . . ??