Last update:
Wed Jan 29 15:20:15 MST 2020
W. G. Forssmann and
L. Girardier A Study of the T System in Rat Heart . . 1
Paul Personne and
Winston Anderson Localisation Mitochondriale D'Enzymes
Liees Au Metabolisme Du Glycogene Dans
Le Spermatozoide De L'Escargot . . . . . 20
Winston A. Anderson and
Paul Personne The Localization of Glycogen in the
Spermatozoa of Various Invertebrate and
Vertebrate Species . . . . . . . . . . . 29
Bernard J. Panner and
Carl R. Honig Locus and State of Aggregation of Myosin
in Tissue Sections of Vertebrate Smooth
Muscle . . . . . . . . . . . . . . . . . 52
Virginia M. Tennyson The Fine Structure of the Axon and
Growth Cone of the Dorsal Root
Neuroblast of the Rabbit Embryo . . . . 62
T. W. Keenan and
D. James Morré and
Diane E. Olson and
W. N. Yunghans and
Stuart Patton Biochemical and Morphological Comparison
of Plasma Membrane and Milk Fat Globule
Membrane from Bovine Mammary Gland . . . 80
B. P. Gerhardt and
Harry Beevers Developmental Studies on Glyoxysomes in
Ricinus Endosperm . . . . . . . . . . . 94
Stephen R. Gross and
Lewis Aronow and
William B. Pratt The Outward Transport of Cortisol by
Mammalian Cells in Vitro . . . . . . . . 103
David Bodian An Electron Microscopic Characterization
of Classes of Synaptic Vesicles by Means
of Controlled Aldehyde Fixation . . . . 115
Camillo Peracchia A System of Parallel Septa in Crayfish
Nerve Fibers . . . . . . . . . . . . . . 125
Richard Bischoff and
Howard Holtzer Inhibition of Myoblast Fusion After One
Round of DNA Synthesis in
$5$-Bromodeoxyuridine . . . . . . . . . 134
Mary A. Bonneville and
Melvyn Weinstock Brush Border Development in the
Intestinal Absorptive Cells of
\bionameXenopus During Metamorphosis . . 151
Edmund B. Masurovsky and
Helena H. Benitez and
Seung U. Kim and
Margaret R. Murray Origin, Development, and Nature of
Intranuclear Rodlets and Associated
Bodies in Chicken Sympathetic Neurons 172
Daniel Szollosi Cortical Cytoplasmic Filaments of
Cleaving Eggs: a Structural Element
Corresponding to the Contractile Ring 192
William H. J. Douglas and
Robert C. Ripley and
Richard A. Ellis Enzymatic Digestion of Desmosome and
Hemidesmosome Plaques Performed on
Ultrathin Sections . . . . . . . . . . . 211
Yasuo Uehara and
Geoffrey Burnstock Demonstration of ``Gap Junctions''
Between Smooth Muscle Cells . . . . . . 215
Sherman Bloom Structural Changes in Nuclear Envelopes
During Elongation of Heart Muscle Cells 218
A. Sengel and
P. Stoebner Golgi Origin of Tubular Inclusions in
Endothelial Cells . . . . . . . . . . . 223
Janardan Reddy and
Masahiro Chiga and
Sukhum Bunyaratvej and
Donald Svoboda Microbodies in Experimentally Altered
Cells . . . . . . . . . . . . . . . . . 226
Robert Marantz and
Michael L. Shelanski Structure of Microtubular Crystals
Induced by Vinblastine in Vitro . . . . 234
David M. Phillips Insect Sperm: Their Structure and
Morphogenesis . . . . . . . . . . . . . 243
W. H. Butler and
J. D. Judah Preparation of Isolated Rat Liver
Mitochondria for Electron Microscopy . . 278
K. W. Henningsen and
J. E. Boynton Macromolecular Physiology of Plastids 290
I. W. Craig and
A. Gibor A Direct Light Effect on Maintaining
Photosynthetic Activity of Nitella
Chloroplasts . . . . . . . . . . . . . . 305
Elinor S. Mills and
Yale J. Topper Some Ultrastructural Effects of Insulin,
Hydrocortisone, and Prolactin on Mammary
Gland Explants . . . . . . . . . . . . . 310
K. E. Kuettner and
L. W. Soble and
R. D. Ray and
R. L. Croxen and
M. Passovoy and
R. Eisenstein Lysozyme in Epiphyseal Cartilage . . . . 329
Arthur R. Hand The Fine Structure of Von Ebner's Gland
of the Rat . . . . . . . . . . . . . . . 340
Joseph B. Warshaw and
Mary L. Terry Cellular Energy Metabolism During Fetal
Development . . . . . . . . . . . . . . 354
Christopher L. F. Woodcock and
Lawrence Bogorad Evidence for Variation in the Quantity
of DNA Among Plastids of Acetabularia 361
Richard W. Hendler and
Amelia H. Burgess and
Raymond Scharff Respiration and Protein Synthesis in
\bionameEscherichia coli
Membrane-Envelope Fragments . . . . . . 376
Laurent Descarries and
Bernard Droz Intraneural Distribution of Exogenous
Norepinephrine in the Central Nervous
System of the Rat . . . . . . . . . . . 385
Elliott Robbins and
Thoru Pederson and
Paul Klein Comparison of Mitotic Phenomena and
Effects Induced by Hypertonic Solutions
in HeLa Cells . . . . . . . . . . . . . 400
Daniel W. McKeel and
Leonard Jarett Preparation and Characterization of a
Plasma Membrane Fraction from Isolated
Fat Cells . . . . . . . . . . . . . . . 417
Ray F. Everet and
Bharati P. Deshpande Nuclear P Protein in Sieve Elements of
\bionameTilia Americana . . . . . . . . 462
Talat A. Khan and
Jane Overton Lanthanum Staining of Developing Chick
Cartilage and Reaggregating Cartilage
Cells . . . . . . . . . . . . . . . . . 433
Eric Holtzman and
Alan R. Freeman and
Leonard A. Kashner A Cytochemical and Electron Microscope
Study of Channels in the Schwann Cells
Surrounding Lobster Giant Axons . . . . 438
Wolf H. Fahrenbach The Cyanoblast: Hemocyanin Formation in
Limulus Polyphemus . . . . . . . . . . . 445
John W. Moser and
Gerald L. Kreitner Centrosome Structure in Anthoceros
Laevis and Marchantia Polymorpha . . . . 454
F. P. Moss and
C. P. Leblond Nature of Dividing Nuclei in Skeletal
Muscle of Growing Rats . . . . . . . . . 459
Ruy Soeiro and
James E. Darnell A Comparison Between Heterogeneous
Nuclear RNA and Polysomal Messenger RNA
in HeLa Cells by RNA-DNA Hybridization 467
Gerassimos N. Pagoulatos and
James E. Darnell A Comparison of the Heterogeneous
Nuclear RNA of HeLa Cells in Different
Periods of the Cell Growth Cycle . . . . 476
D. James Morré and
R. L. Hamilton and
H. H. Mollenhauer and
R. W. Mahley and
W. P. Cunningham and
R. D. Cheetham and
V. S. Lequire Isolation of a Golgi Apparatus-Rich
Fraction from Rat Liver . . . . . . . . 484
R. D. Cheetham and
D. James Morré and
Wayne N. Yunghans Isolation of a Golgi Apparatus-Rich
Fraction from Rat Liver . . . . . . . . 492
Robert M. Lavker and
A. Gedeon Matoltsy Formation of Horny Cells . . . . . . . . 501
Sidney Goldfischer and
Alex B. Novikoff and
Arline Albala and
Luis Biempica Hemoglobin Uptake by Rat Hepatocytes and
Its Breakdown Within Lysosomes . . . . . 513
R. K. Togasaki and
R. P. Levine Chloroplast structure and function in
\bionameac-20, a mutant strain of
\bionameChlamydomonas reinhardi . . . . 531
R. P. Levine and
A. Paszewski Chloroplast structure and function in
\bionameac-20, a mutant strain of
\bionameChlamydomonas reinhardi . . . . 540
Ursula W. Goodenough and
R. P. Levine Chloroplast structure and function in
\bionameac-20, a mutant strain of
\bionameChlamydomonas reinhardi . . . . 547
I. Goldberg and
I. Ohad Biogenesis of Chloroplast Membranes . . 563
I. Goldberg and
I. Ohad Biogenesis of Chloroplast Membranes . . 572
M. V. L. Bennett and
J. P. Trinkaus Electrical Coupling Between Embryonic
Cells by Way of Extracellular Space and
Specialized Junctions . . . . . . . . . 592
R. E. Stephens and
R. E. Kane Some Properties of Hyalin . . . . . . . 611
Benita De Petrocellis and
Philip Siekevitz and
George E. Palade Changes in chemical composition of
thylakoid membranes during greening of
the \bionamey-1 mutant of
\bionameChlamydomonas reinhardi . . . . 618
Joseph Bryan The Isolation of a Major Structural
Element of the Sea Urchin Fertilization
Membrane . . . . . . . . . . . . . . . . 635
Russell Ross and
Newton B. Everett and
Ruth Tyler Wound Healing and Collagen Formation . . 645
Judy M. Strum and
Morris J. Karnovsky Cytochemical Localization of Endogenous
Peroxidase in Thyroid Follicular Cells 655
J. Stuve and
P. Galle Role of Mitochondria in the Handling of
Gold by the Kidney . . . . . . . . . . . 667
H. Hartman and
R. M. Dowben Polyribosomes from \bionameTetrahymena 676
H. Firket and
A. F. Hopper Abnormal Cycle Phase Durations in
Polyploid Cells Or Cells with Irregular
Mitosis in a HeLa Cell Population . . . 678
Baccio Baccetti and
Romano Dallai and
Floriana Rosati The Spermatozoon of Arthropoda . . . . . 681
Martin Hagopian and
David Spiro Derivation of the Z Line in the
Embryonic Chick Heart . . . . . . . . . 683
Richard R. Lynn and
Paul T. Magee Development of the Spore Wall During
Ascospore Formation in
\bionameSaccharomyces Cerevisiae . . . . 688
Paul R. Burton Optical Diffraction and Translational
Reinforcement of Microtubules Having a
Prominent Helical Wall Structure . . . . 693
R. J. Podolsky and
T. Hall and
S. L. Hatchett Identification of Oxalate Precipitates
in Striated Muscle Fibers . . . . . . . 699
Emma Shelton and
Edward L. Kuff and
Elizabeth S. Maxwell and
J. T. Harrington Cytoplasmic Particles and Aminoacyl
Transferase I Activity . . . . . . . . . 1
J. J. Mire and
W. J. Hendelman and
R. P. Bunge Observations on a Transient Phase of
Focal Swelling in Degenerating
Unmyelinated Nerve Fibers . . . . . . . 9
H. Bruce Bosmann and
R. Alan Winston Synthesis of Glycoprotein, Glycolipid,
Protein, and Lipid in Synchronized
L5178Y Cells . . . . . . . . . . . . . . 23
Robert L. Trelstad The Golgi Apparatus in Chick Corneal
Epithelium: Changes in Intracellular
Position During Development . . . . . . 34
A. J. Solari and
Laura L. Tres The Three-Dimensional Reconstruction of
the XY Chromosomal Pair in Human
Spermatocytes . . . . . . . . . . . . . 43
Dorothy Ford Bainton and
Marilyn G. Farquhar Segregation and Packaging of Granule
Enzymes in Eosinophilic Leukocytes . . . 54
Robert J. Klebe and
Tchaw-Ren Chen and
Frank H. Ruddle Controlled Production of Proliferating
Somatic Cell Hybrids . . . . . . . . . . 74
Charles C. Childress and
Bertram Sacktor and
I. William Grossman and
Ernest Bueding Isolation, Ultrastructure, and
Biochemical Characterization of Glycogen
in Insect Flight Muscle . . . . . . . . 83
Judson D. Sheridan Low-Resistance Junctions Between Cancer
Cells in Various Solid Tumors . . . . . 91
Mary A. Grillo Cytoplasmic Inclusions Resembling
Nucleoli in Sympathetic Neurons of Adult
Rats . . . . . . . . . . . . . . . . . . 100
Peter G. Legg and
Richard L. Wood New Observations on Microbodies . . . . 118
G. Blobel and
D. D. Sabatini Controlled Proteolysis of Nascent
Polypeptides in Rat Liver Cell Fractions 130
D. D. Sabatini and
G. Blobel Controlled Proteolysis of Nascent
Polypeptides in Rat Liver Cell Fractions 146
Bong Yul Yoo Ultrastructural Changes in Cells of Pea
Embryo Radicles During Germination . . . 158
Wiktor Djaczenko and
Arrigo Benedetto and
Renato Pezzi Formation of Helical Polyribosomes in
Poliovirus-Infected Cells of the 37 Rc
Line . . . . . . . . . . . . . . . . . . 173
Sibdas Ghosh and
Renate Lettré and
Ira Ghosh DNA Synthetic Pattern in the Nucleolus 177
Sibdas Ghosh and
Ira Ghosh DNA Synthetic Pattern in the Nucleolus 181
Thoru Pederson and
Seymour Gelfant Macromolecular Synthesis in Dogfish
Peripheral Blood Cells . . . . . . . . . 183
Filiberto Giacomelli and
Joseph Wiener and
David Spiro Cross-Striated Arrays of Filaments in
Endothelium . . . . . . . . . . . . . . 188
Jacob Dyckman and
Joel K. Weltman A Morphological Analysis of Binding of a
Hydrophobic Probe to Cells . . . . . . . 192
R. G. Herrmann and
K. V. Kowallik Selective Presentation of DNA-Regions
and Membranes in Chloroplasts and
Mitochondria . . . . . . . . . . . . . . 198
Wincenty Kilarski and
Andrzej Jasi\'nski The Formation of Multivesicular Bodies
from the Nuclear Envelope . . . . . . . 205
Fredrick J. Seil and
Robert M. Herndon Cerebellar Granule Cells in Vitro . . . 212
Anders Hamberger and
Christian Blomstrand and
Albert L. Lehninger Comparative Studies on Mitochondria
Isolated from Neuron-Enriched and
Glia-Enriched Fractions of Rabbit and
Beef Brain . . . . . . . . . . . . . . . 221
Edith K. MacRae and
Gerald D. Meetz Electron Microscopy of the Ammoniacal
Silver Reaction for Histones in the
Erythropoietic Cells of the Chick . . . 235
R. Malcolm Brown and
Werner W. Franke and
Hans Kleinig and
Heinz Falk and
Peter Sitte Scale Formation in Chrysophycean Algae 246
Daniel A. Goodenough and
Jean Paul Revel A Fine Structural Analysis of
Intercellular Junctions in the Mouse
Liver . . . . . . . . . . . . . . . . . 272
T. L. Chan and
John W. Greenawalt and
Peter L. Pedersen Biochemical and Ultrastructural
Properties of a Mitochondrial Inner
Membrane Fraction Deficient in Outer
Membrane and Matrix Activities . . . . . 291
Anthony P. Mahowald and
Joan M. Strassheim Intercellular Migration of Centrioles in
the Germarium of \bionameDrosophila
Melanogaster . . . . . . . . . . . . . . 306
Peter G. Canonico and
John W. C. Bird Lysosomes in Skeletal Muscle Tissue . . 321
Jerome J. Freed and
Marcia M. Lebowitz The Association of a Class of Saltatory
Movements with Microtubules in Cultured
Cells . . . . . . . . . . . . . . . . . 334
Carlos J. Tandler and
César M. Libanati and
Carlos A. Sanchis The Intracellular Localization of
Inorganic Cations with Potassium
Pyroantimonate . . . . . . . . . . . . . 355
Robert M. Rosenbaum and
Murray Wittner Ultrastructure of Bacterized and Axenic
Trophozoites of Entamoeba Histolytica
with Particular Reference to Helical
Bodies . . . . . . . . . . . . . . . . . 367
Barry A. Palevitz and
Eldon H. Newcomb A Study of Sieve Element Starch Using
Sequential Enzymatic Digestion and
Electron Microscopy . . . . . . . . . . 383
S. M. Cocucci and
M. Sussman RNA in Cytoplasmic and Nuclear Fractions
of Cellular Slime Mold Amebas . . . . . 399
Brian Poole and
Tokuhiko Higashi and
Christian de Duve The Synthesis and Turnover of Rat Liver
Peroxisomes . . . . . . . . . . . . . . 408
Jerome S. Kaye The Fine Structure and Arrangement of
Microcylinders in the Lumina of
Flagellar Fibers in Cricket Spermatids 416
D. Zirwer and
E. Buder and
W. Schälike and
R. Wetzel Lineardichroitische Untersuchungen zur
DNS-Organisation in Spermienköpfen von
\bionameLocusta Migratoria L. (German)
[Linear dichroitics on DNA organization
in sperm heads of \bionameLocusta
Migratoria L] . . . . . . . . . . . . . 431
Allen L. Horwitz and
Albert Dorfman The Growth of Cartilage Cells in Soft
Agar and Liquid Suspension . . . . . . . 434
Peter K. Hepler and
J. Richard McIntosh and
Story Cleland Intermicrotubule Bridges in Mitotic
Spindle Apparatus . . . . . . . . . . . 438
Ulrich Scheer The Ultrastructure of the Nuclear
Envelope of Amphibian Oocytes: a
Reinvestigation . . . . . . . . . . . . 445
Steven C. Mohos and
Lorant Skoza Variations in the Sialic Acid
Concentration of Glomerular Basement
Membrane Preparations Obtained by
Ultrasonic Treatment . . . . . . . . . . 450
Milton J. Finegold and
Laura E. Greene Mitochondrial Damage in Experimental
Congenital Adrenal Hyperplasia . . . . . 455
Dougald G. Scott and
Charles W. Daniel Filaments in the Division Furrow of
Mouse Mammary Cells . . . . . . . . . . 461
J. Norman Grim Ultrastructure of Ciliary Microtubules
After Critical Point Drying . . . . . . 466
John Aronson and
Shinya Inoué Reversal by Light of the Action of
N-Methyl N-Desacetyl Colchicine on
Mitosis . . . . . . . . . . . . . . . . 470
L. Recher and
J. Whitescarver and
L. Briggs A Cytochemical and Radioautographic
Study of Human Tissue Culture Cell
Nucleoli . . . . . . . . . . . . . . . . 479
George Weinbaum and
Donald A. Fischman and
Shinichi Okuda Membrane Modifications in Nutritionally
Induced Filamentous \bionameEscherichia
coli B . . . . . . . . . . . . . . . . . 493
Thoru Pederson and
Elliott Robbins Absence of Translational Control of
Histone Synthesis During the HeLa Cell
Life Cycle . . . . . . . . . . . . . . . 509
David E. F. Harrison Undamped Oscillations of Pyridine
Nucleotide and Oxygen Tension in
Chemostat Cultures of Klebsiella
Aerogenes . . . . . . . . . . . . . . . 514
Robert J. Mclean and
George F. Pessoney A Large Scale Quasi-Crystalline Lamellar
Lattice in Chloroplasts of the Green
Alga Zygnema . . . . . . . . . . . . . . 522
Lennart Boquist Cilia and Vesicular Particles in the
Endocrine Pancreas of the Mongolian
Gerbil . . . . . . . . . . . . . . . . . 532
R. M. Hicks and
B. Ketterer Isolation of the Plasma Membrane of the
Luminal Surface of Rat Bladder
Epithelium, and the Occurrence of a
Hexagonal Lattice of Subunits Both in
Negatively Stained Whole Mounts and in
Sectioned Membranes . . . . . . . . . . 542
Nessly C. Craig and
Robert P. Perry Aberrant Intranucleolar Maturation of
Ribosomal Precursors in the Absence of
Protein Synthesis . . . . . . . . . . . 554
Nicholas C. Spitzer Low Resistance Connections Between Cells
in the Developing Anther of the Lily . . 565
Richard L. Wood and
Peter G. Legg Peroxidase Activity in Rat Liver
Microbodies After Amino-Triazole
Inhibition . . . . . . . . . . . . . . . 576
Marco Baggiolini and
James G. Hirsch and
Christian de Duve Further Biochemical and Morphological
Studies of Granule Fractions from Rabbit
Heterophil Leukocytes . . . . . . . . . 586
Pedro Pinto da Silva and
Daniel Branton Membrane Splitting in Freeze-Etching . . 598
Joseph Bryan On the Reconstitution of the Crystalline
Components of the Sea Urchin
Fertilization Membrane . . . . . . . . . 606
R. E. Kane Direct Isolation of the Hyaline Layer
Protein Released from the Cortical
Granules of the Sea Urchin Egg at
Fertilization . . . . . . . . . . . . . 615
Ajit Kumar Ribosome Synthesis in
\bionameTetrahymena Pyriformis . . . . . 623
Richard Rodewald Selective Antibody Transport in the
Proximal Small Intestine of the Neonatal
Rat . . . . . . . . . . . . . . . . . . 635
Yoshiyuki Ichikawa and
Masao Kuroda and
Toshio Yamano Zonation of hemoprotein P-450 and
cytochrome $ b_5 $ in the adrenocortex
of mammals . . . . . . . . . . . . . . . 640
Sin Hang Lee The Possible Role of the Vesicles in
Renal Ammonia Excretion . . . . . . . . 644
Thomas W. Tillack and
Vincent T. Marchesi Demonstration of the Outer Surface of
Freeze-Etched Red Blood Cell Membranes 649
Kiyoshi Hama and
Fumio Nagata A Stereoscope Observation of Tracheal
Epithelium of Mouse by Means of the High
Voltage Electron Microscope . . . . . . 654
B. W. Payton Histological Staining Properties of
Procion Yellow M4Rs . . . . . . . . . . 659
Peter Barland and
Eleanor A. Schroeder A New Rapid Method for the Isolation of
Surface Membranes from Tissue Culture
Cells . . . . . . . . . . . . . . . . . 662
Gary Bennett Migration of Glycoprotein from Golgi
Apparatus to Cell Coat in the Columnar
Cells of the Duodenal Epithelium . . . . 668
Yutaka Tashiro and
Eiichi Otsuki Studies on the Posterior Silk Gland of
the Silkworm Bombix Mori . . . . . . . . 1
John N. Loeb and
Daniel V. Kimberg Sedimentation Properties of Rat Liver
Mitochondria . . . . . . . . . . . . . . 17
Helen A. Padykula and
Geraldine F. Gauthier The Ultrastructure of the Neuromuscular
Junctions of Mammalian Red, White, and
Intermediate Skeletal Muscle Fibers . . 27
Isaac Schenkein and
Jonathan W. Uhr Immunoglobulin Synthesis and Secretion 42
Daniel Zagury and
Jonathan W. Uhr and
James D. Jamieson and
George E. Palade Immunoglobulin Synthesis and Secretion 52
Virginia M. Tennyson and
Miro Brzin The Appearance of Acetylcholinesterase
in the Dorsal Root Neuroblast of the
Rabbit Embryo . . . . . . . . . . . . . 64
Robert S. Redman and
Leo M. Sreebny Proliferative Behavior of
Differentiating Cells in the Developing
Rat Parotid Gland . . . . . . . . . . . 81
K. Watson and
J. M. Haslam and
Anthony W. Linnane Biogenesis of Mitochondria . . . . . . . 88
J. M. Hanifin and
M. J. Cline Human Monocytes and Macrophages . . . . 97
Peter M. M. Rae The Nature and Processing of Ribosomal
Ribonucleic Acid in a Dinoflagellate . . 106
Richard W. Hendler and
N. Nanninga Respiration and Protein Synthesis in
\bionameEscherichia coli
Membrane-Envelope Fragments . . . . . . 114
A. Tixier-Vidal and
D. Gourdji Synthesis and Renewal of Proteins in
Duck Anterior Hypophysis in Organ
Culture . . . . . . . . . . . . . . . . 130
Hans-G. Heidrich and
Roland Stahn and
Kurt Hannig The Surface Charge of Rat Liver
Mitochondria and Their Membranes . . . . 137
R. A. Tobey and
K. D. Ley Regulation of Initiation of DNA
Synthesis in Chinese Hamster Cells . . . 151
Eiichi Tani and
Toshio Ametani Substructure of Microtubules in Brain
Nerve Cells As Revealed by Ruthenium Red 159
P. Klein and
E. Robbins An Ultrasensitive Assay for Soluble
Sulfhydryl and Its Application to the
Study of Glutathione Levels During the
HeLa Life Cycle . . . . . . . . . . . . 165
M. A. Venkatachalam and
M. H. Soltani and
H. Dariush Fahimi Fine Structural Localization of
Peroxidase Activity in the Epithelium of
Large Intestine of Rat . . . . . . . . . 168
John W. Greenawalt and
Carl Schnaitman An Appraisal of the Use of Monoamine
Oxidase As an Enzyme Marker for the
Outer Membrane of Rat Liver Mitochondria 173
James M. Hyde and
Dietrich Peters The Influence of pH and Osmolality on
Fixation of the Fowlpox Virus Core . . . 179
W. F. Harris The Arrangement of the Axonemal
Microtubules and Links of
Echinosphaerium Nucleofilum . . . . . . 183
Joseph Tupper and
John W. Saunders and
Charles Edwards The Onset of Electrical Communication
Between Cells in the Developing Starfish
Embryo . . . . . . . . . . . . . . . . . 187
Erwin Huebner and
Everett Anderson The Effects of Vinblastine Sulfate on
the Microtubular Organization of the
Ovary of Rhodnius Prolixus . . . . . . . 191
David S. Smith and
U. Järlfors and
R. Beránek The Organization of Synaptic Axoplasm in
the Lamprey (\bionamePetromyzon Marinus)
Central Nervous System . . . . . . . . . 199
F. Rudolf Turner The Effects of Colchicine on
Spermatogenesis in Nitella . . . . . . . 220
Donald R. DiBona and
Mortimer M. Civan The Effect of Smooth Muscle on the
Intercellular Spaces in Toad Urinary
Bladder . . . . . . . . . . . . . . . . 235
Bland S. Montenecourt and
Margaret E. Langsam and
Donald T. Dubin Mitochondrial RNA from Cultured Animal
Cells . . . . . . . . . . . . . . . . . 245
Daniel S. Friend and
Gail E. Brassil Osmium Staining of Endoplasmic Reticulum
and Mitochondria in the Rat Adrenal
Cortex . . . . . . . . . . . . . . . . . 252
Thomas D. Pollard and
Susumu Ito Cytoplasmic Filaments of Amoeba Proteus 267
Z. W. Hall and
M. D. Bownds and
E. A. Kravitz The Metabolism of Gamma Aminobutyric
Acid in the Lobster Nervous System . . . 290
Isabelle R. Faeder and
Miriam M. Salpeter Glutamate Uptake by a Stimulated Insect
Nerve Muscle Preparation . . . . . . . . 300
Frank J. Longo and
Everett Anderson The Effects of Nicotine on Fertilization
in the Sea Urchin, \bionameArbacia
Punctulata . . . . . . . . . . . . . . . 308
Samuel W. Cushman Structure-Function Relationships in the
Adipose Cell . . . . . . . . . . . . . . 326
Samuel W. Cushman Structure-Function Relationships in the
Adipose Cell . . . . . . . . . . . . . . 342
Samuel W. Cushman and
Martin A. Rizack Structure-Function Relationships in the
Adipose Cell . . . . . . . . . . . . . . 354
Geert Ab and
Ronald A. Malt Metabolism of Ribosomal Precursor
Ribonucleic Acid in Kidney . . . . . . . 362
T. Tidwell The Methylation of Transfer Ribonucleic
Acid During Regeneration of the Liver 370
Werner W. Franke and
Barbara Deumling and
Baerbel Ermen and
Ernst-Dieter Jarasch and
Hans Kleinig Nuclear Membranes from Mammalian Liver 379
Hans Kleinig Nuclear Membranes from Mammalian Liver 396
Bunsuke Osogoe and
Ayako Ueki A Radioautographic Study of the
Utilization of Deoxycytidine for the
Formation of Deoxyribonucleic
Acid-Thymine in Lymphocytes . . . . . . 403
P. L. Senger and
R. G. Saacke Unusual Mitochondria of the Bovine
Oocyte . . . . . . . . . . . . . . . . . 405
G. Bennett and
C. P. Leblond Formation of Cell Coat Material for the
Whole Surface of Columnar Cells in the
Rat Small Intestine, As Visualized by
Radioautography with L-Fucose-$^3$H . . 409
R. E. Stephens and
E. E. Levine Some Enzymatic Properties of Axonemes
from the Cilia of Pecten Irradians . . . 416
Doreen E. Ashhurst An Insect Desmosome . . . . . . . . . . 421
H. J. Arnott and
A. C. G. Best and
J. A. C. Nicol Occurrence of Melanosomes and of Crystal
Sacs Within the Same Cell in the
\bionameTapetum Lucidum of the Stingaree 426
Costante Ceccarini and
Maria S. Campo and
Franca Andronico Ribosomal Subunit Exchange in
\bionameDictyostelium Purpureum . . . . 428
Robert D. Prusch and
Philip B. Dunham Contraction of Isolated Contractile
Vacuoles from Amoeba Proteus . . . . . . 431
Eugene L. Vigil Cytochemical and Developmental Changes
in Microbodies (Glyoxysomes) and Related
Organelles of Castor Bean Endosperm . . 435
Kate M. Baldwin The Fine Structure and Electrophysiology
of Heart Muscle Cell Injury . . . . . . 455
R. A. Boshes Drosophila Polyribosomes . . . . . . . . 477
John Walberg Anderson and
Milton B. Yatvin Metabolic and Ultrastructural Changes in
the Frog Ovarian Follicle in Response to
Pituitary Stimulation . . . . . . . . . 491
Frank A. Rawlins and
Betty G. Uzman Retardation of Peripheral Nerve
Myelination in Mice Treated with
Inhibitors of Cholesterol Biosynthesis 505
Betrand Bordier and
Leonard Ornstein and
Richard P. Wedeen The Intrarenal Distribution of Tritiated
Para-Aminohippuric Acid Determined by a
Modified Technique of Section Freeze-Dry
Radioautography . . . . . . . . . . . . 518
William R. Jeffery and
Kenneth D. Stuart and
Joseph Frankel The Relationship Between
Deoxyribonucleic Acid Replication and
Cell Division in Heat-Synchronized
\bionameTetrahymena . . . . . . . . . . 533
R. D. Yates and
I-Li Chen and
Donald Duncan Effects of Sinus Nerve Stimulation on
Carotid Body Glomus Cells . . . . . . . 544
Lyndell L. Millecchia and
Maria A. Rudzinska Basal Body Replication and Ciliogenesis
in a Suctorian, \bionameTokophrya
Infusionum . . . . . . . . . . . . . . . 553
Lewis G. Tilney and
Janette Goddard Nucleating Sites for the Assembly of
Cytoplasmic Microtubules in the
Ectodermal Cells of Blastulae of
\bionameArbacia Punctulata . . . . . . . 564
R. Stahn and
K.-P. Maier and
K. Hannig A New Method for the Preparation of Rat
Liver Lysosomes . . . . . . . . . . . . 576
A. C. Esterhuizen and
S. L. Howell Ultrastructure of the A-Cells of Cat
Islets of Langerhans Following
Sympathetic Stimulation of Glucagon
Secretion . . . . . . . . . . . . . . . 593
Sarah P. Gibbs Nuclear and Organelle RNA Synthesis in
Ochromonas: the Effects of Light . . . . 599
Gerd G. Maul Ultrastructure of Pore Complexes of
Annulate Lamellae . . . . . . . . . . . 604
J. W. I. M. Simons Characterization of Somatic Cells by
Determination of Their Volumes with a
Coulter Counter . . . . . . . . . . . . 610
William G. Walther and
Leland N. Edmunds Periodic Increase in Deoxyribonuclease
Activity During the Cell Cycle in
Synchronized Euglena . . . . . . . . . . 613
Izhak Nir and
Arnold M. Seligman Photooxidation of Diaminobenzidine (Dab)
by Chloroplast Lamellae . . . . . . . . 617
Gary E. Wise and
Charles J. Flickinger Cytochemical Staining of the Golgi
Apparatus in Amoeba Proteus . . . . . . 620
Reuben Eisenstein and
Charalampos Arsenis and
Klaus E. Kuettner Electron Microscopic Studies of
Cartilage Matrix Using Lysozyme As a
Vital Stain . . . . . . . . . . . . . . 626
A. Martinez-Palomo and
J. Alanis and
D. Benitez Transitional Cardiac Cells of the
Conductive System of the Dog Heart . . . 1
S. C. Lakhotia and
A. S. Mukherjee Chromosomal Basis of Dosage Compensation
in \bionameDrosophila . . . . . . . . . 18
Hans Glaumann and
Gustav Dallner Subfractionation of Smooth Microsomes
from Rat Liver . . . . . . . . . . . . . 34
J. P. Chalcroft and
S. Bullivant An Interpretation of Liver Cell Membrane
and Junction Structure Based on
Observation of Freeze-Fracture Replicas
of Both Sides of the Fracture . . . . . 49
Armen H. Tashjian and
Frank C. Bancroft and
Lawrence Levine Production of Both Prolactin and Growth
Hormone by Clonal Strains of Rat
Pituitary Tumor Cells . . . . . . . . . 61
J. M. Papadimitriou and
P. Van Duijn Effects of Fixation and Substrate
Protection on the Isoenzymes of
Aspartate Aminotransferase Studied in a
Quantitative Cytochemical Model System 71
J. M. Papadimitriou and
P. Van Duijn The Ultrastructural Localization of the
Isozymes of Aspartate Aminotransferase
in Murine Tissues . . . . . . . . . . . 84
Jean H. Priest and
Robert H. Shikes Distribution of Labeled Chromatin . . . 99
S. Schiaffino and
V\vera Hanzlíková and
Sandra Pierobon Relations Between Structure and Function
in Rat Skeletal Muscle Fibers . . . . . 107
Samuel B. Horowitz and
I. Robert Fenichel Analysis of Sodium Transport in the
Amphibian Oocyte by Extractive and
Radioautographic Techniques . . . . . . 120
O. Wesley McBride and
Elbert A. Peterson Separation of Nuclei Representing
Different Phases of the Growth Cycle
from Unsynchronized Mammalian Cell
Cultures . . . . . . . . . . . . . . . . 132
Martin I. Sachs and
Everett Anderson A Cytological Study of Artificial
Parthenogenesis in the Sea Urchin
\bionameArbacia Punctulata . . . . . . . 140
Fred D. Warner New Observations on Flagellar Fine
Structure . . . . . . . . . . . . . . . 159
Robert V. Rice and
Joan A. Moses and
G. M. McManus and
Arlene C. Brady and
Lorraine M. Blasik The Organization of Contractile
Filaments in a Mammalian Smooth Muscle 183
Peter B. Armstrong A Fine Structural Study of Adhesive Cell
Junctions in Heterotypic Cell Aggregates 197
J. Y. Haga and
M. G. Hamilton and
M. L. Petermann Electron Microscopic Observations on the
Large Subunit of the Rat Liver Ribosome 211
Philip L. Ballard and
Gordon M. Tomkins Glucocorticoid-Induced Alteration of the
Surface Membrane of Cultured Hepatoma
Cells . . . . . . . . . . . . . . . . . 222
Brian S. Spooner and
Bernt T. Walther and
William J. Rutter The Development of the Dorsal and
Ventral Mammalian Pancreas in Vivo and
in Vitro . . . . . . . . . . . . . . . . 235
H. Dariush Fahimi The Fine Structural Localization of
Endogenous and Exogenous Peroxidase
Activity in Kupffer Cells of Rat Liver 247
M. M. Magalhães and
Antonio Coimbra Electron Microscope Radioautographic
Study of Glycogen Synthesis in the
Rabbit Retina . . . . . . . . . . . . . 263
Peter A. Nickerson and
Floyd R. Skelton and
Agostino Molteni Observation of Filaments in the Adrenal
of Androgen-Treated Rats . . . . . . . . 277
Rudolf Vracko and
Earl P. Benditt Capillary Basal Lamina Thickening . . . 281
Gerhard Schreiber and
Rainer Lesch and
Ursula Weinssen and
Josef Zähringer The Distribution of Albumin Synthesis
Throughout the Liver Lobule . . . . . . 285
B. Hellman and
I.-B. Täljedal Solubilizing Effect of Nucleotides on
Isolated Insulin Secretory Granules . . 289
Dorothea Zucker-Franklin The Submembranous Fibrils of Human Blood
Platelets . . . . . . . . . . . . . . . 293
R. G. Kessel The Permeability of Dragonfly Malpighian
Tubule Cells to Protein Using
Horseradish Peroxidase As a Tracer . . . 299
C. Ward Kischer and
Joe S. Keeter Prostaglandin-B$_1$, Embryonic Skin, and
the Dermo--Epidermal Junction . . . . . 303
Roslyn B. Weinstein and
Elizabeth D. Hay Deoxyribonucleic Acid Synthesis and
Mitosis in Differentiated Cardiac Muscle
Cells of Chick Embryos . . . . . . . . . 310
Anders Hamberger and
Hans-Arne Hansson and
Johan Sjöstrand Surface Structure of Isolated Neurons 319
Satoru Murakami and
Lester Packer Protonation and Chloroplast Membrane
Structure . . . . . . . . . . . . . . . 332
Jacques Padawer The Reaction of Rat Mast Cells to
Polylysine . . . . . . . . . . . . . . . 352
W. J. Larsen Genesis of Mitochondria in Insect Fat
Body . . . . . . . . . . . . . . . . . . 373
Joel B. Kirkpatrick and
Lyon Hyams and
Virginia L. Thomas and
Peter M. Howley Purification of Intact Microtubules from
Brain . . . . . . . . . . . . . . . . . 384
John A. Kloetzel Compartmentalization of the Developing
Macronucleus Following Conjugation in
Stylonychia and Euplotes . . . . . . . . 395
Lewis G. Tilney and
Robert R. Cardell Factors Controlling the Reassembly of
the Microvillous Border of the Small
Intestine of the Salamander . . . . . . 408
Thomas L. Lentz Development of the Neuromuscular
Junction . . . . . . . . . . . . . . . . 423
Trudy M. Forte and
John G. Forte Histochemical Staining and
Characterization of Glycoproteins in
Acid-Secreting Cells of Frog Stomach . . 437
K. D. Ley and
R. A. Tobey Regulation of Initiation of DNA
Synthesis in Chinese Hamster Cells . . . 453
Kuruganti G. Murti and
David M. Prescott Micronuclear Ribonucleic Acid in
\bionameTetrahymena Pyriformis . . . . . 460
P. Satir and
N. B. Gilula The Cell Junction in a Lamellibranch
Gill Ciliated Epithelium . . . . . . . . 468
Clara Franzini-Armstrong Studies of the Triad . . . . . . . . . . 488
Charles T. Ladoulis and
Thomas J. Gill Physical Chemical Studies on the
Specific Interaction of an
Acriflavine-Phosphotungstic Acid Complex
with Double-Stranded Nucleic Acids . . . 500
Fredric J. Silverblatt and
Ruth Ellen Bulger Gap Junctions Occur in Vertebrate Renal
Proximal Tubule Cells . . . . . . . . . 513
Evelyn Anagnosti and
Henry Tedeschi The Mechanism of Low-Amplitude
Orthophosphate-Induced Swelling in
Isolated Rat Liver Mitochondria . . . . 520
Edgar F. Carell and
Pamela Leban Johnston and
Alan R. Christopher Vitamin B$_{12}$ and the Macromolecular
Composition of Euglena . . . . . . . . . 525
Gertrude W. Hinsch Possible Role of Intranuclear Membranes
in Nuclear-Cytoplasmic Exchange in
Spider Crab Oocytes . . . . . . . . . . 531
Charles J. Kovacs and
Jack Van't Hof Synchronization of a Proliferative
Population in a Cultured Plant Tissue 536
Arthur R. Hand Nerve-Acinar Cell Relationships in the
Rat Parotid Gland . . . . . . . . . . . 540
David Shepro and
Frank A. Belamarich and
Lois Robblee and
Francis C. Chao Antimotility Effect of Cytochalasin B
Observed in Mammalian Clot Retraction 544
Mary A. Grillo Extracellular Synaptic Vesicles in the
Mouse Heart . . . . . . . . . . . . . . 547
Hans Glaumann and
Jan L. E. Ericsson Evidence for the Participation of the
Golgi Apparatus in the Intracellular
Transport of Nascent Albumin in the
Liver Cell . . . . . . . . . . . . . . . 555
John R. Kennedy and
Arthur M. Zimmerman The Effects of High Hydrostatic Pressure
on the Microtubules of
\bionameTetrahymena Pyriformis . . . . . 568
J. J. Kennelly and
R. H. Foote and
R. C. Jones Duration of Premeiotic Deoxyribonucleic
Acid Synthesis and the Stages of
Prophase I in Rabbit Oocytes . . . . . . 577
George D. Bittner and
Donald Kennedy Quantitative Aspects of Transmitter
Release . . . . . . . . . . . . . . . . 585
A. Gedeon Matoltsy and
Margit N. Matoltsy The Chemical Nature of Keratohyalin
Granules of the Epidermis . . . . . . . 593
Oscar Touster and
N. N. Aronson and
John T. Dulaney and
Herman Hendrickson Isolation of Rat Liver Plasma Membranes 604
Martin A. Gorovsky Studies on Nuclear Structure and
Function in \bionameTetrahymena
Pyriformis . . . . . . . . . . . . . . . 619
Martin A. Gorovsky Studies on Nuclear Structure and
Function in \bionameTetrahymena
Pyriformis . . . . . . . . . . . . . . . 631
Sosamma J. Berger and
Bertram Sacktor Isolation and Biochemical
Characterization of Brush Borders from
Rabbit Kidney . . . . . . . . . . . . . 637
Frank J. Longo and
Everett Anderson A Cytological Study of the Relation of
the Cortical Reaction to Subsequent
Events of Fertilization in
Urethane-Treated Eggs of the Sea Urchin,
\bionameArbacia Punctulata . . . . . . . 646
Hans E. Rugstad and
Stephen H. Robinson and
Claudine Yannoni and
Armen H. Tashjian Metabolism of Bilirubin by a Clonal
Strain of Rat Hepatoma Cells . . . . . . 703
Everett Anderson A Cytological Study of the Centrifuged
Whole, Half, and Quarter Eggs of the Sea
Urchin \bionameArbacia Punctulata . . . 711
Thoru Pederson and
Elliott Robbins RNA Synthesis in HeLa Cells . . . . . . 734
Albert Claude Growth and Differentiation of
Cytoplasmic Membranes in the Course of
Lipoprotein Granule Synthesis in the
Hepatic Cell . . . . . . . . . . . . . . 745
N. Scott McNutt and
Ronald S. Weinstein The Ultrastructure of the Nexus . . . . 666
Hartmut C. Renger and
David R. Wolstenholme Kinetoplast Deoxyribonucleic Acid of the
Hemoflagellate Trypanosoma Lewisi . . . 689
G. Lawrence Vankin and
E. Michael Brandt and
William DeWitt Ultrastructural Studies of Red Blood
Cells from Thyroxin-Treated \bionameRana
Catesbeiana Tadpoles . . . . . . . . . . 767
Volker Speth and
Frank Wunderlich The Macronuclear Envelope of
\bionameTetrahymena Pyriformis Gl in
Different Physiological States . . . . . 772
Brian Coyne and
Joel L. Rosenbaum Flagellar Elongation and Shortening in
Chlamydomonas . . . . . . . . . . . . . 777
Trudy M. Forte and
John G. Forte Definition of the Extracellular Space in
Secreting and Nonsecreting Oxyntic Cells 782
Eve Barak Briles and
Alexander Tomasz Radioautographic Evidence for Equatorial
Wall Growth in a Gram-Positive Bacterium 786
Martin Hagopian Contraction Bands at Short Sarcomere
Length in Chick Muscle . . . . . . . . . 790
Karl T. Kleeman and
J. L. Fryer and
K. S. Pilcher Observed Differences in CO$_2$
Requirements Between Mammalian and
Salmonid Fish Cell Lines . . . . . . . . 796
Edward W. Millhouse and
John J. Chiakulas and
Lawrence E. Scheving Long-Term Organ Culture of the
Salamander Heart . . . . . . . . . . . . 1
Charles N. David and
Kenneth Easterbrook Ferritin in the Fungus Phycomyces . . . 15
Nicholas J. Gross Control of Mitochondrial Turnover Under
the Influence of Thyroid Hormone . . . . 29
Gerd G. Maul and
J. A. Brumbaugh On the Possible Function of Coated
Vesicles in Melanogenesis of the
Regenerating Fowl Feather . . . . . . . 41
R. J. Baskin Ultrastructure and Calcium Transport in
Crustacean Muscle Microsomes . . . . . . 49
M. Locke and
J. T. McMahon The Origin and Fate of Microbodies in
the Fat Body of an Insect . . . . . . . 61
Peter R. Dallman and
Joseph R. Goodman The Effects of Iron Deficiency on the
Hepatocyte: a Biochemical and
Ultrastructural Study . . . . . . . . . 79
François M. M. Morel and
Richard F. Baker and
Harold Wayland Quantitation of Human Red Blood Cell
Fixation by Glutaraldehyde . . . . . . . 91
R. A. Leyton and
E. H. Sonnenblick Cardiac Muscle of the Horseshoe Crab,
Limulus Polyphemus . . . . . . . . . . . 101
E. Egyházi and
B. Daneholt and
J.-E. Edström and
B. Lambert and
U. Ringborg Intracellular Distribution of Low
Molecular Weight RNA in Chironomus
Tentans . . . . . . . . . . . . . . . . 120
Yutaka Shimada Electron Microscope Observations on the
Fusion of Chick Myoblasts in Vitro . . . 128
Birgit Satir and
Ellen Roter Dirksen Nucleolar Aging in \bionameTetrahymena
During the Cultural Growth Cycle . . . . 143
David T. Moran and
Kent M. Chapman and
Richard A. Ellis The Fine Structure of Cockroach
Campaniform Sensilla . . . . . . . . . . 155
Jack Rosenbluth Myosin-Like Aggregates in
Trypsin-Treated Smooth Muscle Cells . . 174
John H. Youson Prismatic Cristae and Matrix Granules in
Mitochondria of the Kidneys of
Ammocoetes . . . . . . . . . . . . . . . 189
B. K. Ghosh Grooves in the Plasmalemma of
\bionameSaccharomyces Cerevisiae Seen in
Glancing Sections of Double
Aldehyde-Fixed Cells . . . . . . . . . . 192
C. J. Bentzel and
D. R. Tourville and
B. Parsa and
T. B. Tomasi Bidirectional Transport of Horseradish
Peroxidase in Proximal Tubule of
Necturus Kidney . . . . . . . . . . . . 197
Samar Chatterjee and
Lester Goldstein Proteins in Nucleocytoplasmic
Interactions . . . . . . . . . . . . . . 202
C. C. Clawson and
Robert A. Good Micropapillae . . . . . . . . . . . . . 207
J. Robert Waaland and
Susan Drury Waaland and
Daniel Branton Gas Vacuoles . . . . . . . . . . . . . . 212
Thomas D. Pollard and
Edward D. Korn Filaments of Amoeba Proteus . . . . . . 216
N. Nanninga The Mesosome of Bacillus Subtilis As
Affected by Chemical and Physical
Fixation . . . . . . . . . . . . . . . . 219
Brian S. Spooner and
S. Robert Hilfer The Expression of Differentiation by
Chick Embryo Thyroid in Cell Culture . . 225
Camillo A. Benzo and
Andrew M. Nemeth Factors Controlling Development of Chick
Embryo Liver Cells During Organ Culture 235
S. H. Socher and
D. Davidson $5$-Aminouracil Treatment . . . . . . . 248
G. A. Mueller and
Mary Esther Gaulden and
Wanzer Drane The Effects of Varying Concentrations of
Colchicine on the Progression of
Grasshopper Neuroblasts into Metaphase 253
William H. Massover Intramitochondrial Yolk-Crystals of Frog
Oocytes . . . . . . . . . . . . . . . . 266
E. Gantt and
M. R. Edwards and
L. Provasoli Chloroplast Structure of the
Cryptophyceae . . . . . . . . . . . . . 280
D. R. Myron and
J. L. Connelly The Morphology of the Swelling Process
in Rat Liver Mitochondria . . . . . . . 291
Steven J. Hausman and
Lucy M. Anderson and
William H. Telfer The Dependence of Cecropia Yolk
Formation in Vitro on Specific Blood
Proteins . . . . . . . . . . . . . . . . 303
Abraham L. Kierszenbaum and
Cesar M. Libanati and
Carlos J. Tandler The Distribution of Inorganic Cations in
Mouse Testis . . . . . . . . . . . . . . 314
Thomas Bibring and
Jane Baxandall Selective Extraction of Isolated Mitotic
Apparatus . . . . . . . . . . . . . . . 324
Ellen Kundrat and
Frank A. Pepe The M Band . . . . . . . . . . . . . . . 340
Henry deF. Webster The Geometry of Peripheral Myelin
Sheaths During Their Formation and
Growth in Rat Sciatic Nerves . . . . . . 348
J. H. Hardin and
S. S. Spicer Ultrastructural Localization of Dialyzed
Iron-Reactive Mucosubstance in Rabbit
Heterophils, Basophils, and Eosinophils 368
Hilton H. Mollenhauer and
Clara Totten Studies on Seeds . . . . . . . . . . . . 387
Hilton H. Mollenhauer and
Clara Totten Studies on Seeds . . . . . . . . . . . . 395
Awtar Krishan and
Dora Hsu Binding of Colchicine-$^3$H to
Vinblastine- and Vincristine-Induced
Crystals in Mammalian Tissue Culture
Cells . . . . . . . . . . . . . . . . . 407
Michael K. Nemanic and
Dorothy R. Pitelka A Scanning Electron Microscope Study of
the Lactating Mammary Gland . . . . . . 410
A. Macieira-Coelho and
D. Brouty-Boyé and
M. T. Thomas and
I. Gresser Interferon and Cell Division . . . . . . 415
J. D. Hall and
F. L. Crane Intracristal Rods . . . . . . . . . . . 420
Fotis C. Kafatos and
Vassili Kiortsis The Packaging of a Secretory Protein . . 426
Ronald D. MacDonald and
Andrew G. Engel Observations on Organization of Z-Disk
Components and on Rod-Bodies of Z-Disk
Origin . . . . . . . . . . . . . . . . . 431
Lawrence L. Espey Multivesicular Structures in
Proliferating Fibroblasts of Rabbit
Ovarian Follicles During Ovulation . . . 437
A. R. Stevens and
D. M. Prescott Reformation of Nucleolus-Like Bodies in
the Absence of Postmitotic RNA Synthesis 443
Thomas L. Lentz and
J. P. Trinkaus Differentiation of the Junctional
Complex of Surface Cells in the
Developing Fundulus Blastoderm . . . . . 455
Russell L. Deter Quantitative Characterization of Dense
Body, Autophagic Vacuole, and Acid
Phosphatase-Bearing Particle Populations
During the Early Phases of
Glucagon-Induced Autophagy in Rat Liver 473
S. Jakovcic and
G. S. Getz and
M. Rabinowitz and
H. Jakob and
H. Swift Cardiolipin Content of Wild Type and
Mutant Yeasts in Relation to
Mitochondrial Function and Development 490
James D. Jamieson and
George E. Palade Condensing Vacuole Conversion and
Zymogen Granule Discharge in Pancreatic
Exocrine Cells: Metabolic Studies . . . 503
Yasusada Miura and
Fred H. Wilt The Effects of $5$-Bromodeoxyuridine on
Yolk Sac Erythropoiesis in the Chick
Embryo . . . . . . . . . . . . . . . . . 523
Hilton H. Mollenhauer and
Clara Totten Studies on Seeds . . . . . . . . . . . . 533
C. Freeman Allen and
Pearl Good and
Hilton H. Mollenhauer and
Clara Totten Studies on Seeds . . . . . . . . . . . . 542
Adolph I. Cohen Electron Microscope Observations on Form
Changes in Photoreceptor Outer Segments
and Their Saccules in Response to
Osmotic Stress . . . . . . . . . . . . . 547
Ken Shortman and
Neil Williams and
Heather Jackson and
Pamela Russell and
Pauline Byrt and
E. Diener The Separation of Different Cell Classes
from Lymphoid Organs . . . . . . . . . . 566
R. Seegmiller and
F. C. Fraser and
H. Sheldon A New Chondrodystrophic Mutant in Mice 580
Ursula W. Goodenough and
L. Andrew Staehelin Structural Differentiation of Stacked
and Unstacked Chloroplast Membranes . . 594
Werner Straus Comparative Analysis of the
Concentration of Injected Horseradish
Peroxidase in Cytoplasmic Granules of
the Kidney Cortex, in the Blood, Urine,
and Liver . . . . . . . . . . . . . . . 620
Joram Heller and
Thomas J. Ostwald and
Dean Bok The Osmotic Behavior of Rod
Photoreceptor Outer Segment Discs . . . 633
Olivia C. McKenna and
Jack Rosenbluth Characterization of an Unusual
Catecholamine-Containing Cell Type in
the Toad Hypothalamus . . . . . . . . . 650
Ruben Laguens Morphometric Study of Myocardial
Mitochondria in the Rat . . . . . . . . 673
John W. Combs An Electron Microscope Study of Mouse
Mast Cells Arising in Vivo and in Vitro 676
Alain Perrelet and
Lelio Orci and
Fritz Baumann Evidence for Granulolysis in the
Retinula Cells of a Stomatopod
Crustacean, Squilla Mantis . . . . . . . 684
Robert L. Trelstad Vacuoles in the Embryonic Chick Corneal
Epithelium, an Epithelium Which Produces
Collagen . . . . . . . . . . . . . . . . 689
Jared Grantham and
F. E. Cuppage and
Darrell Fanestil Direct Observation of Toad Bladder
Response to Vasopressin . . . . . . . . 695
Takashi Iwayama and
J. B. Furness Enhancement of the Granulation of
Adrenergic Storage Vesicles in Drug-Free
Solution . . . . . . . . . . . . . . . . 699
Jochen W. Heine and
Carl A. Schnaitman A Method for the Isolation of Plasma
Membrane of Animal Cells . . . . . . . . 703
David Bodian Presynaptic Organelles and Junctional
Integrity . . . . . . . . . . . . . . . 707
Robert L. Benson and
Bertram Sacktor and
John W. Greenawalt Studies on the Ultrastructural
Localization of Intestinal
Disaccharidases . . . . . . . . . . . . 711
Richard D. Allen Fine Structure of Membranous and
Microfibrillar Systems in the Cortex of
Paramecium Caudatum . . . . . . . . . . 1
Gordon R. Campbell and
Yasuo Uehara and
Gerda Mark and
Geoffrey Burnstock Fine Structure of Smooth Muscle Cells
Grown in Tissue Culture . . . . . . . . 21
Colvin M. Redman Phospholipid Metabolism in Intact and
Modified Erythrocyte Membranes . . . . . 35
Paul H. Jewett and
J. R. Sommer and
E. A. Johnson Cardiac Muscle . . . . . . . . . . . . . 50
Mina Perlin and
Jules V. Hallum Effect of acid pH on macromolecular
synthesis in L cells . . . . . . . . . . 66
Paula M. Orkand and
Edward A. Kravitz Localization of the sites of $ \gamma
$-aminobutyric acid (GABA) uptake in
lobster nerve--muscle preparations . . . 75
E. M. Eddy and
Susumu Ito Fine Structural and Radioautographic
Observations on Dense Perinuclear
Cytoplasmic Material in Tadpole Oocytes 90
J. Meldolesi and
J. D. Jamieson and
G. E. Palade Composition of Cellular Membranes in the
Pancreas of the Guinea Pig . . . . . . . 109
J. Meldolesi and
J. D. Jamieson and
G. E. Palade Composition of Cellular Membranes in the
Pancreas of the Guinea Pig . . . . . . . 130
J. Meldolesi and
J. D. Jamieson and
G. E. Palade Composition of Cellular Membranes in the
Pancreas of the Guinea Pig . . . . . . . 150
Y. Asada and
M. V. L. Bennett Experimental Alteration of Coupling
Resistance at an Electrotonic Synapse 159
George D. Pappas and
Y. Asada and
M. V. L. Bennett Morphological Correlates of Increased
Coupling Resistance at an Electrotonic
Synapse . . . . . . . . . . . . . . . . 173
K. D. Stuart Evidence for the Retention of
Kinetoplast DNA in an
Acriflavine-Induced Dyskinetoplastic
Strain of Trypanosoma Brucei Which
Replicates the Altered Central Element
of the Kinetoplast . . . . . . . . . . . 189
Clara Franzini-Armstrong Studies of the Triad . . . . . . . . . . 196
Robert C. Shaler and
Richard L. McCarl The Mechanism of Cortisol Action in
Cultured Rat Heart Cells . . . . . . . . 205
G. M. Vassart and
J. E. Dumont and
F. R. L. Cantraine Interpretation of Surface Aspects of
Cell Sections . . . . . . . . . . . . . 210
Hilton H. Mollenhauer Fragmentation of Mature
\bionameDictyosome Cisternae . . . . . . 212
Ronald J. Przybylski Occurrence of Centrioles During Skeletal
and Cardiac Myogenesis . . . . . . . . . 214
Charles J. Flickinger Decreased Formation of Golgi Bodies in
Amebae in the Presence of RNA and
Protein Synthesis Inhibitors . . . . . . 221
Virginia G. Fonte and
Robert L. Searls and
S. Robert Hilfer The Relationship of Cilia with Cell
Division and Differentiation . . . . . . 226
J. D. Chapman and
R. G. Webb and
J. Borsa ATP Pool Levels in Synchronously Growing
Chinese Hamster Cells . . . . . . . . . 229
K. J. Ryan and
H. Kalant and
E. Llewellyn Thomas Free-Flow Electrophoretic Separation and
Electrical Surface Properties of
Subcellular Particles from Guinea Pig
Brain . . . . . . . . . . . . . . . . . 235
Walter S. Krawczyk A Pattern of Epidermal Cell Migration
During Wound Healing . . . . . . . . . . 247
A. Leskes and
P. Siekevitz and
G. E. Palade Differentiation of Endoplasmic Reticulum
in Hepatocytes . . . . . . . . . . . . . 264
A. Leskes and
P. Siekevitz and
G. E. Palade Differentiation of Endoplasmic Reticulum
in Hepatocytes . . . . . . . . . . . . . 288
Richard W. Young The Renewal of Rod and Cone Outer
Segments in the Rhesus Monkey . . . . . 303
Eveline E. Schneeberger and
Morris J. Karnovsky The Influence of Intravascular Fluid
Volume on the Permeability of Newborn
and Adult Mouse Lungs to Ultrastructural
Protein Tracers . . . . . . . . . . . . 319
A. M. Kelly Sarcoplasmic Reticulum and T Tubules in
Differentiating Rat Skeletal Muscle . . 335
Hilary K. Darrah and
John Hedley-Whyte and
E. Tessa Hedley-Whyte Radioautography of Cholesterol in Lung 345
Pat G. Model and
Murray B. Bornstein and
Stanley M. Crain and
George D. Pappas An Electron Microscopic Study of the
Development of Synapses in Cultured
Fetal Mouse Cerebrum Continuously
Exposed to Xylocaine . . . . . . . . . . 362
George M. Maniatis and
Vernon M. Ingram Erythropoiesis During Amphibian
Metamorphosis . . . . . . . . . . . . . 372
George M. Maniatis and
Vernon M. Ingram Erythropoiesis During Amphibian
Metamorphosis . . . . . . . . . . . . . 380
George M. Maniatis and
Vernon M. Ingram Erythropoiesis During Amphibian
Metamorphosis . . . . . . . . . . . . . 390
Arthur R. Ugel Studies on Isolated Aggregating
Oligoribonucleoproteins of the Epidermis
with Histochemical and Morphological
Characteristics of Keratohyalin . . . . 405
Madhu M. Bhargava and
Harlyn O. Halvorson Isolation of Nuclei from Yeast . . . . . 423
E. A. Comissiong and
D. W. Stanley and
H. O. Hultin Inhibition of Emptying of Skeletal
Muscle Cell Segments by Adenine
Nucleotides and Polyvalent Cations . . . 430
Heschel J. Raskas and
Case K. Okubo Transport of Viral RNA in Kb Cells
Infected with Adenovirus Type 2 . . . . 438
K. E. Kuettner and
R. Eisenstein and
L. W. Soble and
C. Arsenis Lysozyme in Epiphyseal Cartilage . . . . 450
C. Arsenis and
R. Eisenstein and
L. W. Soble and
K. E. Kuettner Enzyme Activities in Chick Embryonic
Cartilage . . . . . . . . . . . . . . . 459
J. Richard McIntosh and
Story C. Landis The Distribution of Spindle Microtubules
During Mitosis in Cultured Human Cells 468
V. L. Rudick Relationships Between Nucleic Acid
Synthetic Patterns and Encystment in
Aging Unagitated Cultures of
\bionameAcanthamoeba Castellanii . . . . 498
Fathy E. Mattar and
Thomas J. Byers Morphological Changes and the
Requirements for Macromolecule Synthesis
During Excystment of
\bionameAcanthamoeba Castellanii . . . . 507
Takashi Iwayama Nexuses Between Areas of the Surface
Membrane of the Same Arterial Smooth
Muscle Cell . . . . . . . . . . . . . . 521
Robert J. Pariser and
Dennis D. Cunningham Transport Inhibitors Released by 3T3
Mouse Cells and Their Relation to Growth
Control . . . . . . . . . . . . . . . . 525
F. Malaisse-Lagae and
M. H. Greider and
W. J. Malaisse and
P. E. Lacy The Stimulus-Secretion Coupling of
Glucose-Induced Insulin Release . . . . 530
William E. Cassady and
Robert P. Wagner Separation of Mitochondrial Membranes of
Neurospora Crassa . . . . . . . . . . . 536
R. Lenk and
S. Penman Morphological Studies of Cells Grown in
the Absence of Mitochondrial-Specific
Protein Synthesis . . . . . . . . . . . 541
Henry B. Horwitz and
Charles E. Holt Specific Inhibition by Ethidium Bromide
of Mitochondrial DNA Synthesis in
\bionamePhysarum Polycephalum . . . . . 546
Woutera van Iterson and
J. B. Groen DNA-Membrane Complexes of Bacillus
Subtilis . . . . . . . . . . . . . . . . 553
John Oberpriller and
Jean C. Oberpriller Mitosis in Adult Newt Ventricle . . . . 560
N. Nanninga Uniqueness and Location of the Fracture
Plane in the Plasma Membrane of Bacillus
Subtilis . . . . . . . . . . . . . . . . 564
Q. Bone and
E. J. Denton The Osmotic Effects of Electron
Microscope Fixatives . . . . . . . . . . 571
Sandra K. Masur and
Eric Holtzman and
Irving L. Schwartz and
Roderich Walter Correlation Between Pinocytosis and
Hydroosmosis Induced by Neurohypophyseal
Hormones and Mediated by Adenosine
3',5'-Cyclic Monophosphate . . . . . . . 582
Brian S. Spooner and
Kenneth M. Yamada and
Norman K. Wessells Microfilaments and Cell Locomotion . . . 595
Kenneth M. Yamada and
Brian S. Spooner and
Norman K. Wessells Ultrastructure and Function of Growth
Cones and Axons of Cultured Nerve Cells 614
Carrick E. Devine and
Andrew P. Somlyo Thick Filaments in Vascular Smooth
Muscle . . . . . . . . . . . . . . . . . 636
H. Clarke Anderson and
Stanley W. Sajdera The Fine Structure of Bovine Nasal
Cartilage . . . . . . . . . . . . . . . 650
Dean Bok and
Michael O. Hall The Role of the Pigment Epithelium in
the Etiology of Inherited Retinal
Dystrophy in the Rat . . . . . . . . . . 664
Se Yong Lee and
Velibor Krsmanovic and
George Brawerman Attachment of Ribosomes to Membranes
During Polysome Formation in Mouse
Sarcoma 180 Cells . . . . . . . . . . . 683
Brigid Hogan and
Paul R. Gross The Effect of Protein Synthesis
Inhibition on the Entry of Messenger RNA
into the Cytoplasm of Sea Urchin Embryos 692
Sharon V. Radford and
Donald W. Misch The Cytological Effect of Ecdysterone on
the Midgut Cells of the Flesh-Fly
Sarcophaga Bullata . . . . . . . . . . . 702
Yoshinori Nozawa and
Guy A. Thompson Studies of Membrane Formation in
\bionameTetrahymena Pyriformis . . . . . 712
Yoshinori Nozawa and
Guy A. Thompson Studies of Membrane Formation in
\bionameTetrahymena Pyriformis . . . . . 722
W. Bernhard and
Annie Viron Improved Techniques for the Preparation
of Ultrathin Frozen Sections . . . . . . 731
Barbara Szubinska ''New Membrane'' Formation in Amoeba
Proteus Upon Injury of Individual Cells 747
Yvonne Kress and
Murray Wittner and
Robert M. Rosenbaum Sites of Cytoplasmic
Ribonucleoprotein-Filament Assembly in
Relation to Helical Body Formation in
Axenic Trophozoites of Entamoeba
Histolytica . . . . . . . . . . . . . . 773
Stephanie G. Phillips and
David M. Phillips Nucleoli of Diploid Cell Strains . . . . 785
David M. Phillips and
Stephanie G. Phillips Distinctive Characteristics of Nucleoli
of Two Established Cell Lines . . . . . 803
Jean-Claude Wanson and
Louis Tielemans Morphological and Biochemical
Characteristics of Glycogen Particles
Isolated from Rabbit Polymorphonuclear
Leukocytes . . . . . . . . . . . . . . . 816
J. S. Noel and
W. C. Dewey and
J. H. Abel and
R. P. Thompson Ultrastructure of the Nucleolus During
the Chinese Hamster Cell Cycle . . . . . 830
Stephen E. Malawista The Melanocyte Model . . . . . . . . . . 848
A. Haddad and
Meredith D. Smith and
Annette Herscovics and
N. J. Nadler and
C. P. Leblond Radioautographic Study of in Vivo and in
Vitro Incorporation of Fucose-$^3$H into
Thyroglobulin by Rat Thyroid Follicular
Cells . . . . . . . . . . . . . . . . . 856
A. Nakamura and
F. Sreter and
J. Gergely Comparative Studies of Light Meromyosin
Paracrystals Derived from Red, White,
and Cardiac Muscle Myosins . . . . . . . 883
R. D. Cheetham and
D. James Morré and
Carol Pannek and
Daniel S. Friend Isolation of a Golgi Apparatus-Rich
Fraction from Rat Liver . . . . . . . . 899
Ronald C. Rustad and
Shuhei Yuyama and
Lynne C. Rustad Nuclear-Cytoplasmic Relations in the
Mitosis of Sea Urchin Eggs . . . . . . . 906
R. Meneghini and
H. A. Armelin and
J. Balsamo and
F. J. S. Lara Indication of Gene Amplification in
Rhynchosciara by RNA-DNA Hybridization 913
Morton H. Friedman Arm-Bearing Microtubules Associated with
an Unusual Desmosome-Like Junction . . . 916
E. Brad Thompson and
Gordon M. Tomkins A Histochemical Method for the
Demonstration of Tyrosine
Aminotransferase in Tissue Culture
Cells, and Studies of This Enzyme in
Hepatoma Tissue Culture Cells . . . . . 921
Awtar Krishan and
Dora Hsu Vinblastine-Induced Ribosomal Complexes 927
Mary Bell A Comparative Study of Sebaceous Gland
Ultrastructure in Subhuman Primates . . 932
D. M. Woolley Striations in the Peripheral Fibers of
Rat and Mouse Spermatozoa . . . . . . . 936
Tsuneyoshi Kuroiwa and
Nobunori Tanaka Fine Structures of Interphase Nuclei . . 939
Thoru Pederson and
Elliott Robbins A Method for Improving Synchrony in the
G$_2$ Phase of the Cell Cycle . . . . . 942
John R. Hodgson and
Harold W. Fisher Formation of Polyribosomes During
Recovery from Contact Inhibition of
Replication . . . . . . . . . . . . . . 945
Jean-Marie Gillis and
Maurice Wibo Accurate Measurement of the Thickness of
Ultrathin Sections by Interference
Microscopy . . . . . . . . . . . . . . . 947
I. W. Craig and
A. Gibor Chloroplast Development in Charophyceae 950
LeRoy Kuehl and
Earl N. Sumsion Studies on the Site of Synthesis of
Several Soluble Enzymes of the Cell
Nucleus . . . . . . . . . . . . . . . . 1
George E. Palade Albert Claude and the Beginnings of
Biological Electron Microscopy . . . . . ??
Richard G. W. Anderson and
Robert M. Brenner The Formation of Basal Bodies
(Centrioles) in the Rhesus Monkey
Oviduct . . . . . . . . . . . . . . . . 10
Christian de Duve Tissue Fraction-Past and Present . . . . ??
Ursula W. Goodenough The Effects of Inhibitors of RNA and
Protein Synthesis on Chloroplast
Structure and Function in Wild-Type
Chlamydomonas Reinhardi . . . . . . . . 35
Ursula W. Goodenough and
R. P. Levine The effects of inhibitors of RNA and
protein synthesis on the recovery of
chloroplast ribosomes, membrane
organization, and photosynthetic
electron transport in the \bionameac-20
strain of \bionameChlamydomonas
reinhardi . . . . . . . . . . . . . . . 50
Gary G. Leppard and
J. Ross Colvin and
Dyson Rose and
S. M. Martin Lignofibrils on the External Cell Wall
Surface of Cultured Plant Cells . . . . 63
Daniel A. Goodenough and
Jean-Paul Revel The Permeability of Isolated and in Situ
Mouse Hepatic Gap Junctions Studied with
Enzymatic Tracers . . . . . . . . . . . 81
A. J. Hudspeth and
J. P. Revel Coexistence of Gap and Septate Junctions
in an Invertebrate Epithelium . . . . . 92
Joan A. Higgins and
Russell J. Barrnett Fine Structural Localization of
Acyltransferases . . . . . . . . . . . . 102
Yasuko Nakajima Fine Structure of the Medial Nucleus of
the Trapezoid Body of the Bat with
Special Reference to Two Types of
Synaptic Endings . . . . . . . . . . . . 121
James D. Jamieson and
George E. Palade Synthesis, Intracellular Transport, and
Discharge of Secretory Proteins in
Stimulated Pancreatic Exocrine Cells . . 135
Russell Ross and
Seymour J. Klebanoff The Smooth Muscle Cell . . . . . . . . . 159
Russell Ross The Smooth Muscle Cell . . . . . . . . . 172
Abraham Amsterdam and
Michael Schramm and
Itzhak Ohad and
Yoram Salomon and
Zvi Selinger Concomitant Synthesis of Membrane
Protein and Exportable Protein of the
Secretory Granule in Rat Parotid Gland 187
Winston A. Anderson and
Andrew Spielman Permeability of the Ovarian Follicle of
Aedes Aegypti Mosquitoes . . . . . . . . 201
D. Montgomery Bissell and
Jeremiah G. Tilles Morphology and Function of Cells of
Human Embryonic Liver in Monolayer
Culture . . . . . . . . . . . . . . . . 222
Jeanne Pager Étude Morphométrique du Syst\`eme
Tubulaire Transverse du Myocarde
Ventriculaire de Rat. (French)
[Morphometric Study of the Transverse
Tubular System of Rat Ventricular
Myocardium] . . . . . . . . . . . . . . 233
Gary G. Leppard and
J. Ross Colvin Fine Structure of the Middle Lamella of
Aggregates of Plant Cells in Suspension
Culture . . . . . . . . . . . . . . . . 237
M. S. Shahrabadi and
T. Yamamoto A Method for Staining Intracellular
Antigens in Thin Sections with
Ferritin-Labeled Antibody . . . . . . . 246
George R. Hunter and
Gerald P. Brierley On the ``Energized-Twisted''
Configuration of Isolated Beef Heart
Mitochondria . . . . . . . . . . . . . . 250
John A. Hermos and
Minnie Mathan and
Jerry S. Trier DNA Synthesis and Proliferation by
Villous Epithelial Cells in Fetal Rats 255
Garth L. Nicolson Structure of the Photosynthetic
Apparatus in Protein-Embedded
Chloroplasts . . . . . . . . . . . . . . 258
H. L. Atwood Z and T Tubules in Stomach Muscles of
the Spiny Lobster . . . . . . . . . . . 264
I. Friedberg and
I. Goldberg and
I. Ohad A Prolamellar Body-Like Structure in
Chlamydomonas Reinhardi . . . . . . . . 268
A. Martinez-Palomo and
D. Erlij and
H. Bracho Localization of Permeability Barriers in
the Frog Skin Epithelium . . . . . . . . 277
G. Niemeyer and
W. G. Forssmann Comparison of Glycerol Treatment in Frog
Skeletal Muscle and Mammalian Heart . . 288
Lee V. Leak Studies on the Permeability of Lymphatic
Capillaries . . . . . . . . . . . . . . 300
M. M. Salpeter and
E. E. Salpeter Resolution in Electron Microscope
Radioautography . . . . . . . . . . . . 324
H. Reggio and
H. Cailla-Deckmyn and
G. Marchis-Mouren Effect of Pancreozymin on Rat Pancreatic
Enzyme Biosynthesis . . . . . . . . . . 333
Peter B. Moens and
Ellen Rapport Spindles, Spindle Plaques, and Meiosis
in the Yeast \bionameSaccharomyces
Cerevisiae (Hansen) . . . . . . . . . . 344
G. Benjamin Bouck The Structure, Origin, Isolation, and
Composition of the Tubular Mastigonemes
of the Ochromonas Flagellum . . . . . . 362
Genevieve S. Incefy and
Attallah Kappas Isolation and Biochemical
Characterization of Nuclei from Chick
Embryo Liver . . . . . . . . . . . . . . 385
Walter Rubin and
Michael D. Gershon and
Leonard L. Ross Electron Microscope Radioautographic
Identification of Serotonin-Synthesizing
Cells in the Mouse Gastric Mucosa . . . 399
B. R. Brinkley and
Joiner Cartwright Ultrastructural Analysis of Mitotic
Spindle Elongation in Mammalian Cells in
Vitro . . . . . . . . . . . . . . . . . 416
J. P. Kraehenbuhl and
P. B. De Grandi and
M. A. Campiche Ultrastructural Localization of
Intracellular Antigen Using
Enzyme-Labeled Antibody Fragments . . . 432
P. B. De Grandi and
J. P. Kraehenbuhl and
M. A. Campiche Ultrastructural localization of
calcitonin in the parafollicular cells
of pig thyroid gland with cytochrome
$c$-labeled antibody fragments . . . . . 446
Judith Medoff and
Jerome Gross In Vitro Aggregation of Mixed Embryonic
Kidney and Nerve Cells . . . . . . . . . 457
Norton B. Berg and
Richard W. Young Sulfate Metabolism in Pancreatic Acinar
Cells . . . . . . . . . . . . . . . . . 469
Y. Uehara and
G. R. Campbell and
G. Burnstock Cytoplasmic Filaments in Developing and
Adult Vertebrate Smooth Muscle . . . . . 484
Barbara A. Nichols and
Dorothy Ford Bainton and
Marilyn G. Farquhar Differentiation of Monocytes . . . . . . 498
Rudolf A. Raff and
Gerald Greenhouse and
Kenneth W. Gross and
Paul R. Gross Synthesis and Storage of Microtubule
Proteins by Sea Urchin Embryos . . . . . 516
E. L. Carstensen and
William G. Aldridge and
S. Z. Child and
P. Sullivan and
H. H. Brown Stability of Cells Fixed with
Glutaraldehyde and Acrolein . . . . . . 529
Harmut C. Renger and
David R. Wolstenholme Kinetoplast and other satellite DNAs of
kinetoplastic and dyskinetoplastic
strains of \bionameTrypanosoma . . . . . 533
M. Locke and
N. Krishnan and
J. T. McMahon A Routine Method for Obtaining High
Contrast Without Staining Sections . . . 540
Elizabeth Gillespie Colchicine Binding in Tissue Slices . . 544
M. Locke and
N. Krishnan Hot Alcoholic Phosphotungstic Acid and
Uranyl Acetate As Routine Stains for
Thick and Thin Sections . . . . . . . . 550
Avinash N. Bhisey and
Jerome J. Freed Cross-Bridges on the Microtubules of
Cooled Interphase HeLa Cells . . . . . . 557
C. A. Pasternak and
A. M. H. Warmsley and
D. B. Thomas Structural Alterations in the Surface
Membrane During the Cell Cycle . . . . . 562
Lelio Orci and
Andre E. Lambert and
Yasunori Kanazawa and
Mylene Amherdt and
Charles Rouiller and
Albert E. Renold Morphological and Biochemical Studies of
B Cells of Fetal Rat Endocrine Pancreas
in Organ Culture . . . . . . . . . . . . 565
Ramah W. La Pushin and
Etienne de Harven A Study of Gluco-Corticosteroid-Induced
Pyknosis in the Thymus and Lymph Node of
the Adrenalectomized Rat . . . . . . . . 583
Richard D. Palmiter and
Joan T. Wrenn Interaction of Estrogen and Progesterone
in Chick Oviduct Development . . . . . . 598
Nicolae Simionescu and
George E. Palade Dextrans and Glycogens As Particulate
Tracers for Studying Capillary
Permeability . . . . . . . . . . . . . . 616
Francis J. Chlapowski and
R. Neal Band Assembly of Lipids into Membranes in
\bionameAcanthamoeba Palestinensis . . . 625
Francis J. Chlapowski and
R. Neal Band Assembly of Lipids into Membranes in
\bionameAcanthamoeba Palestinensis . . . 634
Harold Weintraub and
Graham Le M. Campbell and
Howard Holtzer Primitive Erythropoiesis in Early Chick
Embryogenesis . . . . . . . . . . . . . 652
G. Le M. Campbell and
H. Weintraub and
B. H. Mayall and
H. Holtzer Primitive Erythropoiesis in Early Chick
Embryogenesis . . . . . . . . . . . . . 669
Lloyd A. Culp and
William J. Grimes and
Paul H. Black Contact-Inhibited Revertant Cell Lines
Isolated from Sv40-Transformed Cells . . 682
N. Scott McNutt and
Lloyd A. Culp and
Paul H. Black Contact-Inhibited Revertant Cell Lines
Isolated from Sv40-Transformed Cells . . 691
John Rannestad and
Norman E. Williams The Synthesis of Microtubule and Other
Proteins of the Oral Apparatus in
\bionameTetrahymena Pyriformis . . . . . 709
Neil Howell and
Carol A. Zuiches and
Kenneth D. Munkres Mitochondrial Biogenesis in Neurospora
Crassa . . . . . . . . . . . . . . . . . 721
David J. McLaughlin Centrosomes and Microtubules During
Meiosis in the Mushroom Boletus
Rubinellus . . . . . . . . . . . . . . . 737
Stanley G. Sawicki and
Gabriel C. Godman On the Differential Cytotoxicity of
Actinomycin D . . . . . . . . . . . . . 746
Chandler Fulton and
R. E. Kane and
R. E. Stephens Serological Similarity of Flagellar and
Mitotic Microtubules . . . . . . . . . . 762
Jay R. Greenberg and
Robert P. Perry Hybridization Properties of DNA
Sequences Directing the Synthesis of
Messenger RNA and Heterogeneous Nuclear
RNA . . . . . . . . . . . . . . . . . . 774
C. N. Nair and
E. Knight Turnover of HeLa Ribosomal RNA . . . . . 787
Judson D. Sheridan Electrical Coupling Between Fat Cells in
Newt Fat Body and Mouse Brown Fat . . . 795
Roger Wagner and
Murray Rosenberg and
Richard Estensen Endocytosis in Chang Liver Cells . . . . 804
Ronald H. Stevens and
Harold Amos RNA Metabolism in HeLa Cells at Reduced
Temperature . . . . . . . . . . . . . . 818
C. J. Tandler and
A. L. Kierszenbaum Inorganic Cations in Rat Kidney . . . . 830
Robert L. Trelstad and
Alfred J. Coulombre Morphogenesis of the Collagenous Stroma
in the Chick Cornea . . . . . . . . . . 840
Phyllis M. Novikoff and
Alex B. Novikoff and
Nelson Quintana and
Jean-Jacques Hauw Golgi Apparatus, Gerl, and Lysosomes of
Neurons in Rat Dorsal Root Ganglia,
Studied by Thick Section and Thin
Section Cytochemistry . . . . . . . . . 859
P. M. Rose and
A. F. Hopper and
R. W. Wannemacher Cell Population Changes in the
Intestinal Mucosa of Protein-Depleted Or
Starved Rats . . . . . . . . . . . . . . 887
Pieter J. Helmsing and
Hans D. Berendes Induced Accumulation of Nonhistone
Proteins in Polytene Nuclei of
\bionameDrosophila Hydei . . . . . . . . 893
Mercedes R. Edwards and
Elisabeth Gantt Phycobilisomes of the Thermophilic
Blue-Green Alga Synechococcus Lividus 896
Jack Rosenbluth Myosin-Like Tactoids in Trypsin-Treated
Blood Platelets . . . . . . . . . . . . 900
Garth L. Nicolson and
Robert Hyman and
S. J. Singer The Two-Dimensional Topographic
Distribution of H-2 Histocompatibility
Alloantigens on Mouse Red Blood Cell
Membranes . . . . . . . . . . . . . . . 905
E. Joan Blanchette-Mackie and
Robert O. Scow Sites of Lipoprotein Lipase Activity in
Adipose Tissue Perfused with
Chylomicrons . . . . . . . . . . . . . . 1
Alfred Weinstock and
C. P. Leblond Elaboration of the Matrix Glycoprotein
of Enamel by the Secretory Ameloblasts
of the Rat Incisor As Revealed by
Radioautography After Galactose-$^3$H
Injection . . . . . . . . . . . . . . . 26
Maurice Wibo and
Alain Amar-Costesec and
Jacques Berthet and
Henri Beaufay Electron Microscope Examination of
Subcellular Fractions . . . . . . . . . 52
Ernest W. April and
Philip W. Brandt and
Gerald F. Elliott The Myofilament Lattice: Studies on
Isolated Fibers . . . . . . . . . . . . 72
William K. Ovalle Fine Structure of Rat Intrafusal Muscle
Fibers . . . . . . . . . . . . . . . . . 83
Tatsuro Ikeuchi and
Mitsuyoshi Sanbe and
Herbert Weinfeld and
Avery A. Sandberg Induction of Nuclear Envelopes Around
Metaphase Chromosomes After Fusion with
Interphase Cells . . . . . . . . . . . . 104
Robert D. Leibowitz The Effect of Ethidium Bromide on
Mitochondrial DNA Synthesis and
Mitochondrial DNA Structure in HeLa
Cells . . . . . . . . . . . . . . . . . 116
Charles R. Hackenbrock and
Terry G. Rehn and
Eugene C. Weinbach and
John J. Lemasters Oxidative Phosphorylation and
Ultrastructural Transformation in
Mitochondria in the Intact Ascites Tumor
Cell . . . . . . . . . . . . . . . . . . 123
Howard Feit and
Gary R. Dutton and
Samuel H. Barondes and
Michael L. Shelanski Microtubule Protein . . . . . . . . . . 138
Toshio Nagano and
Iwao Ohtsuki Reinvestigation of the Fine Structure of
Reinke's Crystal in the Human Testicular
Interstitial Cell . . . . . . . . . . . 148
Judy M. Strum and
Janice Wicken and
John R. Stanbury and
Morris J. Karnovsky Appearance and Function of Endogenous
Peroxidase in Fetal Rat Thyroid . . . . 162
H. L. Fernandez and
P. R. Burton and
F. E. Samson Axoplasmic Transport in the Crayfish
Nerve Cord . . . . . . . . . . . . . . . 176
Andrew G. Ulsamer and
Paddy L. Wright and
Mary G. Wetzel and
Edward D. Korn Plasma and Phagosome Membranes of
\bionameAcanthamoeba Castellanii . . . . 193
Ferenc Hajós and
Sándor Kerpel-Fronius Electron Microscope Histochemical
Evidence for a Partial Or Total Block of
the Tricarboxylic Acid Cycle in the
Mitochondria of Presynaptic Axon
Terminals . . . . . . . . . . . . . . . 216
Camillo Peracchia and
J. David Robertson Increase in Osmiophilia of Axonal
Membranes of Crayfish As a Result of
Electrical Stimulation, Asphyxia, Or
Treatment with Reducing Agents . . . . . 223
Alfred Zweidler and
Leonard H. Cohen Large-Scale Isolation and Fractionation
of Organs of \bionameDrosophila
Melanogaster Larvae . . . . . . . . . . 240
David D. Wood and
David J. L. Luck A Paracrystalline Inclusion in
Neurospora Crassa . . . . . . . . . . . 249
Garth L. Nicolson and
V. T. Marchesi and
S. J. Singer The Localization of Spectrin on the
Inner Surface of Human Red Blood Cell
Membranes by Ferritin-Conjugated
Antibodies . . . . . . . . . . . . . . . 265
W. P. Cunningham and
H. H. Mollenhauer and
S. E. Nyquist Isolation of Germ Cell Golgi Apparatus
from Seminiferous Tubules of Rat Testes 273
Ellen Roter Dirksen Centriole Morphogenesis in Developing
Ciliated Epithelium of the Mouse Oviduct 286
Liane Beif-Lehrer Actinomycin-D Enhancement of Glutamine
Synthetase Activity in Chick Embryo
Retinas Cultured in the Presence of
Cortisol . . . . . . . . . . . . . . . . 303
Dagmar Iványi Number and Size of Nucleoli in
Binucleate Liver Cells . . . . . . . . . 313
Jane A. Westfall and
S. Yamataka and
Paul D. Enos Ultrastructural Evidence of Polarized
Synapses in the Nerve Net of Hydra . . . 318
Peter A. Simpson and
Allan D. Dingle Variable Periodicity in the Rhizoplast
of Naegleria Flagellates . . . . . . . . 323
Stephen Gobel Axo-Axonic Septate Junctions in the
Basket Formations of the Cat Cerebellar
Cortex . . . . . . . . . . . . . . . . . 328
Jean A. Sage and
Ralph A. Jersild Comparative Distribution of
Carbohydrates and Lipid Droplets in the
Golgi Apparatus of Intestinal Absorptive
Cells . . . . . . . . . . . . . . . . . 333
Ned Feder Microperoxidase . . . . . . . . . . . . 339
G. C. Saunders and
M. Wilder Repetitive Maturation Cycles in a
Cultured Mouse Myeloma . . . . . . . . . 344
Matthew M. Lavail and
Liane Reif-Lehrer Glutamine Synthetase in the Normal and
Dystrophic Mouse Retina . . . . . . . . 348
U. Ringborg and
L. Rydlander Nucleolar-Derived Ribonucleic Acid in
Chromosomes, Nuclear Sap, and Cytoplasm
of Chironomus Tentans Salivary Gland
Cells . . . . . . . . . . . . . . . . . 355
A. R. Luff and
H. L. Atwood Changes in the Sarcoplasmic Reticulum
and Transverse Tubular System of Fast
and Slow Skeletal Muscles of the Mouse
During Postnatal Development . . . . . . 369
Robert A. Briggaman and
Frederic G. Dalldorf and
Clayton E. Wheeler Formation and Origin of Basal Lamina and
Anchoring Fibrils in Adult Human Skin 384
Jacopo Meldolesi and
Dario Cova In Vitro Stimulation of Enzyme Secretion
and the Synthesis of Microsomal
Membranes in the Pancreas of the Guinea
Pig . . . . . . . . . . . . . . . . . . 396
Gerd G. Maul and
Joseph W. Price and
Michael W. Lieberman Formation and Distribution of Nuclear
Pore Complexes in Interphase . . . . . . 405
John B. Richardson and
Aur\`ele Beaulnes The Cellular Site of Action of
Angiotensin . . . . . . . . . . . . . . 419
Linda W. Reynolds and
Vernon M. Ingram Erythroid Cell Differentiation and the
Inhibition of Cytokinesis by
Cytochalasin . . . . . . . . . . . . . . 433
Helen K. Hagopian and
Vernon M. Ingram Developmental Changes of Erythropoiesis
in Cultured Chick Blastoderms . . . . . 440
E. M. Evans and
J. M. Wrigglesworth and
K. Burdett and
W. F. R. Pover Studies on Epithelial Cells Isolated
from Guinea Pig Small Intestine . . . . 452
Pál Röhlich and
Per Anderson and
Börje Uvnäs Electron Microscope Observations on
Compound 48/$ 80$-Induced Degranulation
in Rat Mast Cells . . . . . . . . . . . 465
Nicholas K. Gonatas and
Lucila Autilio-Gambetti and
Pierluigi Gambetti and
Brenda Shafer Morphological and Biochemical Changes in
Rat Synaptosome Fractions During
Neonatal Development . . . . . . . . . . 484
Robert H. Holdsworth The Isolation and Partial
Characterization of the Pyrenoid Protein
of Eremosphaera Viridis . . . . . . . . 499
Gerald Soslau and
Margit M. K. Nass Effects of Ethidium Bromide on the
Cytochrome Content and Ultrastructure of
L Cell Mitochondria . . . . . . . . . . 514
Stephen Roth and
Edward J. McGuire and
Saul Roseman An Assay for Intercellular Adhesive
Specificity . . . . . . . . . . . . . . 525
Stephen Roth and
Edward J. McGuire and
Saul Roseman Evidence for Cell-Surface
Glycosyltransferases . . . . . . . . . . 536
Peter R. Dallman Malnutrition: Incorporation of
Thymidine-$^3$H into Nuclear and
Mitochondrial DNA . . . . . . . . . . . 549
James B. Wade and
Vincent A. Discala The Effect of Osmotic Flow on the
Distribution of Horseradish Peroxidase
Within the Intercellular Spaces of Toad
Bladder Epithelium . . . . . . . . . . . 553
Gerd G. Maul On the Octagonality of the Nuclear Pore
Complex . . . . . . . . . . . . . . . . 558
J. Zalta and
J.-P. Zalta and
R. Simard Isolation of Nucleoli . . . . . . . . . 563
B. D. Mulvaney Chemography of Lysosome-Like Structures
in Olfactory Epithelium . . . . . . . . 568
Judy M. Strum Unusual Peroxidase-Positive Granules in
the Developing Rat Submaxillary Gland 575
John F. Aronson Demonstration of a Colcemid-Sensitive
Attractive Force Acting Between the
Nucleus and a Center . . . . . . . . . . 579
David H. K. Chui and
Meir Djaldetti and
Paul A. Marks and
Richard A. Rifkind Erythropoietin Effects on Fetal Mouse
Erythroid Cells . . . . . . . . . . . . 585
K. Nakagami and
H. Warshawsky and
C. P. Leblond The Elaboration of Protein and
Carbohydrate by Rat Parathyroid Cells As
Revealed by Electron Microscope
Radioautography . . . . . . . . . . . . 596
Stephen M. Shea Lanthanum Staining of the Surface Coat
of Cells . . . . . . . . . . . . . . . . 611
Nobuhisa Baba and
Hari M. Sharma Histochemistry of Lactic Dehydrogenase
in Heart and Pectoralis Muscles of Rat 621
S. Granick and
Donna Granick Nucleolar Necklaces in Chick Embryo
Myoblasts Formed by Lack of Arginine . . 636
Roy S. Wu and
Jonathan R. Warner Cytoplasmic Synthesis of Nuclear
Proteins . . . . . . . . . . . . . . . . 643
J. R. Gautschi and
R. Schindler and
C. Hürni Studies on the Division Cycle of
Mammalian Cells . . . . . . . . . . . . 653
Richard W. Hendler Respiration and Protein Synthesis in
\bionameEscherichia coli
Membrane-Envelope Fragments . . . . . . 664
R. W. Rowe Ultrastructure of the Z Line of Skeletal
Muscle Fibers . . . . . . . . . . . . . 674
H. Rubin pH and population density in the
regulation of animal cell multiplication 686
Virginia M. Tennyson and
Miro Brzin and
Paul Slotwiner The Appearance of Acetylcholinesterase
in the Myotome of the Embryonic Rabbit 703
Andrew P. Somlyo and
Carrick E. Devine and
Avril V. Somlyo and
Stanley R. North Sarcoplasmic Reticulum and the
Temperature-Dependent Contraction of
Smooth Muscle in Calcium-Free Solutions 722
Liselotte Mezger-Freed Puromycin Resistance in Haploid and
Heteroploid Frog Cells: Gene Or Membrane
Determined? . . . . . . . . . . . . . . 742
Robert D. Goldman The Role of Three Cytoplasmic Fibers in
Bhk-21 Cell Motility . . . . . . . . . . 752
Richard H. Colby Intrinsic Birefringence of Glycerinated
Myofibrils . . . . . . . . . . . . . . . 763
A. Kent Christensen Frozen Thin Sections of Fresh Tissue for
Electron Microscopy, with a Description
of Pancreas and Liver . . . . . . . . . 772
N. Scott McNutt and
Robert A. Hershberg and
Ronald S. Weinstein Further Observations on the Occurrence
of Nexuses in Benign and Malignant Human
Cervical Epithelium . . . . . . . . . . 805
Chandler Fulton and
Allan D. Dingle Basal Bodies, But Not Centrioles, in
Naegleria . . . . . . . . . . . . . . . 826
Lewis G. Tilney How Microtubule Patterns Are Generated 837
Christopher S. Potten Early and Late Incorporation of
Tritiated Thymidine into Skin Cells and
the Presence of a Long-Lived
G$_0$-Specific Precursor Pool . . . . . 855
Christopher S. Potten and
Jean C. Schaer Labeling of Murine Mastocytoma Cells in
Vitro with Plasma Tritiated
Thymidine-Labeled Animals . . . . . . . 862
Norton B. Gilula and
Peter Satir Septate and Gap Junctions in Molluscan
Gill Epithelium . . . . . . . . . . . . 869
Garry T. Cole and
Henry C. Aldrich Demonstration of Myelin Figures in
Unfixed, Freeze-Etched Fungus Spores . . 873
G. Bennett and
C. P. Leblond Passage of Fucose-$^3$H Label from the
Golgi Apparatus into Dense and
Multivesicular Bodies in the Duodenal
Columnar Cells and Hepatocytes of the
Rat . . . . . . . . . . . . . . . . . . 875
Werner W. Franke and
Jürgen Kartenbeck and
Hanswalter Zentgraf and
Ulrich Scheer and
Heinz Falk Membrane-To-Membrane Cross-Bridges . . . 881
Carolyn M. Conway Evidence for RNA in the Heavy Bodies of
Sea Urchin Eggs . . . . . . . . . . . . 889
Francis J. Chlapowski Regularly Arranged Particles on the
Inner Lamella of the Plasma Membrane of
\bionameAcanthamoeba Palestinensis . . . 893
Edward F. Haskins and
A. Arlan Hinchee and
Richard A. Cloney The Occurrence of Synaptonemal Complexes
in the Slime Mold Echinostelium Minutum
De Bary . . . . . . . . . . . . . . . . 898
George Gordon Brown and
Walter J. Humphreys Sperm-Egg Interactions of Limulus
Polyphemus with Scanning Electron
Microscopy . . . . . . . . . . . . . . . 904
Allen W. Clark and
William P. Hurlbut and
Alexander Mauro Changes in the Fine Structure of the
Neuromuscular Junction of the Frog
Caused by Black Widow Spider Venom . . . 1
Harold I. Friedman and
Robert R. Cardell Effects of Puromycin on the Structure of
Rat Intestinal Epithelial Cells During
Fat Absorption . . . . . . . . . . . . . 15
S. Schiaffino and
V\vera Hanzlíková Autophagic Degradation of Glycogen in
Skeletal Muscles of the Newborn Rat . . 41
Michael C. O'Neill and
Frank E. Stockdale A Kinetic Analysis of Myogenesis in
Vitro . . . . . . . . . . . . . . . . . 52
W. Gerald Robison Microtubular Patterns in Spermatozoa of
Coccid Insects in Relation to Bending 66
J. Kenneth Hoober A Major Polypeptide of Chloroplast
Membranes of Chlamydomonas Reinhardi . . 84
Tatsuro Ikeuchi and
Herbert Weinfeld and
Avery A. Sandberg Chromosome Pulverization in Micronuclei
Induced by Tritiated Thymidine . . . . . 97
Peter H. Cooke and
Fredric S. Fay Correlation Between Fiber Length,
Ultrastructure, and the Length-Tension
Relationship of Mammalian Smooth Muscle 105
James R. Stewart and
Robert A. Weisman Exocytosis of Latex Beads During the
Encystment of \bionameAcanthamoeba . . . 117
Peter G. W. Plagemann Nucleotide Pools in Novikoff Rat
Hepatoma Cells Growing in Suspension
Culture . . . . . . . . . . . . . . . . 131
M. F. Kramer and
C. Poort Unstimulated Secretion of Protein from
Rat Exocrine Pancreas Cells . . . . . . 147
Jean-Jacques Widmann and
Ramzi S. Cotran and
H. Dariush Fahimi Mononuclear Phagocytes (Kupffer Cells)
and Endothelial Cells . . . . . . . . . 159
Arrigo Benedetto and
Wiktor Djaczenko 37Rc Cells Rapidly Recover Their RNA
Synthesis After Inhibition with High
Doses of Actinomycin D . . . . . . . . . 171
P. G. Whitmore Isolation of Microfibrils from Rat
Vibrissal Follicles . . . . . . . . . . 174
Ben Lung Ultrastructure and Chromatin
Disaggregation of Human Sperm Head with
Thioglycolate Treatment . . . . . . . . 179
Wiktor Djaczenko and
Antonio Cassone Visualization of New Ultrastructural
Components in the Cell Wall of Candida
Albicans with Fixatives Containing Tapo 186
J. P. Tranzer and
M. da Prada and
A. Pletscher Storage of $5$-Hydroxytryptamine in
Megakaryocytes . . . . . . . . . . . . . 191
Tsuranobu Shirahama and
Alan S. Cohen The Role of Mucopolysaccharides in
Vesicle Architecture and Endothelial
Transport . . . . . . . . . . . . . . . 198
Nelly Auerspebg Microfilaments in Epithelial
Morphogenesis . . . . . . . . . . . . . 206
Sandra K. Masur and
Eric Holtzman and
Roderich Walter Hormone-Stimulated Exocytosis in the
Toad Urinary Bladder . . . . . . . . . . 211
Walter Rubin An Unusual Intimate Relationship Between
Endocrine Cells and Other Types of
Epithelial Cells in the Human Stomach 219
Colvin M. Redman and
M. George Cherian The Secretory Pathways of Rat Serum
Glycoproteins and Albumin . . . . . . . 231
Robert D. Goldman The Effects of Cytochalasin B on the
Microfilaments of Baby Hamster Kidney
(Bhk-21) Cells . . . . . . . . . . . . . 246
Frank A. Pepe and
Barbara Drucker The Myosin Filament . . . . . . . . . . 255
Olga Greengard and
Micheline Federman and
W. Eugene Knox Cytomorphometry of Developing Rat Liver
and Its Application to Enzymic
Differentiation . . . . . . . . . . . . 261
Zane B. Carothers Studies of Spermatogenesis in the
Hepaticae . . . . . . . . . . . . . . . 273
Joseph B. Warshaw and
Miriam D. Rosenthal Changes in Glucose Oxidation During
Growth of Embryonic Heart Cells in
Culture . . . . . . . . . . . . . . . . 283
G. S. Stein and
T. W. Borun The Synthesis of Acidic Chromosomal
Proteins During the Cell Cycle of HeLa
S-3 Cells . . . . . . . . . . . . . . . 292
T. W. Borun and
G. S. Stein The Synthesis of Acidic Chromosomal
Proteins During the Cell Cycle of HeLa
S-3 Cells . . . . . . . . . . . . . . . 308
Elroy Cantrell and
Edward Bresnick Benzpyrene Hydroxylase Activity in
Isolated Parenchymal and Nonparenchymal
Cells of Rat Liver . . . . . . . . . . . 316
Jack C. Vaughn and
Lillian A. Thomson A Kinetic Study of DNA and Basic Protein
Metabolism During Spermatogenesis in the
Sand Crab, Emerita Analoga . . . . . . . 322
T. Morimoto and
G. Blobel and
D. D. Sabatini Ribosome Crystallization in Chicken
Embryos . . . . . . . . . . . . . . . . 338
T. Morimoto and
G. Blobel and
D. D. Sabatini Ribosome Crystallization in Chicken
Embryos . . . . . . . . . . . . . . . . 355
Wayne A. Busch and
M. H. Stromer and
Darrel E. Goll and
A. Suzuki Ca$^{2+}$-specific removal of Z lines
from rabbit skeletal muscle . . . . . . 367
William K. Ovalle Fine Structure of Rat Intrafusal Muscle
Fibers . . . . . . . . . . . . . . . . . 382
Arthur R. Hand and
Stephen Gobel The Structural Organization of the
Septate and Gap Junctions of Hydra . . . 397
Philip J. Pawlowski and
Maurice H. Vaughan Comparison of the Relative Synthesis of
the Proteins of the 50 S Ribosomal
Subunit in Growing and Valine-Deprived
HeLa Cells . . . . . . . . . . . . . . . 409
L. R. Ganion and
R. G. Kessel Intracellular Synthesis, Transport, and
Packaging of Proteinaceous Yolk in
Oocytes of Orconectes Immunis . . . . . 420
N. Kraft and
Ken Shortman Differentiation of Antibody-Forming
Cells in Toad Spleen . . . . . . . . . . 438
Arthur R. Ugel and
William Idler Further Characterization of Bovine
Keratohyalin . . . . . . . . . . . . . . 453
Bertram Sacktor and
Yoshio Shimada Degenerative Changes in the Mitochondria
of Flight Muscle from Aging Blowflies 465
Miklós Müller Secretion of Acid Hydrolases and Its
Intracellular Source in
\bionameTetrahymena Pyriformis . . . . . 478
Albert I. Farbman Differentiation of Taste Buds in Organ
Culture . . . . . . . . . . . . . . . . 489
John D. Taylor and
Mac E. Hadley The Fate of Amphibian Egg Melanosomes 493
Nagasumi Yago and
Masatoshi Seki and
Shigetaka Sekiyama and
Shigeru Kobayashi and
Hiromi Kurokawa and
Yuko Iwai and
Fumiaki Sato and
Akihiro Shiragai Growth and Differentiation of
Mitochondria in the Regenerating Rat
Adrenal Cortex . . . . . . . . . . . . . 503
Peter J. Stambrook and
Jesse E. Sisken Induced Changes in the Rates of
Uridine-$^3$H Uptake and Incorporation
During the G$_1$ and S Periods of
Synchronized Chinese Hamster Cells . . . 514
P. Gambetti and
L. A. Autilio-Gambetti and
N. K. Gonatas and
B. Shafer Protein Synthesis in Synaptosomal
Fractions . . . . . . . . . . . . . . . 526
J. V. Simson and
S. S. Spicer Ferritin Particles in Macrophages and in
Associated Mast Cells . . . . . . . . . 536
Christopher C. Widnell Cytochemical Localization of
5'-Nucleotidase in Subcellular Fractions
Isolated from Rat Liver . . . . . . . . 542
H. L. Leffert and
D. Paul Studies on Primary Cultures of
Differentiated Fetal Liver Cells . . . . 559
Lesley Watson Coggins and
Joseph G. Gall The Timing of Meiosis and DNA Synthesis
During Early Oogenesis in the Toad,
\bionameXenopus Laevis . . . . . . . . . 569
Minnie Mathan and
John A. Hermos and
Jerry S. Trier Structural Features of the
Epithelio-Mesenchymal Interface of Rat
Duodenal Mucosa During Development . . . 577
Frank E. Stockdale and
Michael C. O'neill Repair DNA Synthesis in Differentiated
Embryonic Muscle Cells . . . . . . . . . 589
Heidi Smith-Johannsen and
Sarah P. Gibbs Effects of Chloramphenicol on
Chloroplast and Mitochondrial
Ultrastructure in Ochromonas Danica . . 598
F. A. Rawlins and
G. M. Villegas and
E. T. Hedley-Whyte and
B. G. Uzman Fine Structural Localization of
Cholesterol-1,2-$^3$H in Degenerating
and Regenerating Mouse Sciatic Nerve . . 615
Arieh Gilai and
I. Parnas Electromechanical Coupling in Tubular
Muscle Fibers . . . . . . . . . . . . . 626
David B. Dusenbery and
Robert B. Uretz The Orientation of DNA Within $
80$-Angstrom Chromatin Fibers . . . . . 639
Vivianne T. Nachmias Electron Microscope Observations on
Myosin from \bionamePhysarum
Polycephalum . . . . . . . . . . . . . . 648
Merton R. Bernfield and
Shib D. Banerjee Acid Mucopolysaccharide
(Glycosaminoglycan) at the
Epithelial-Mesenchymal Interface of
Mouse Embryo Salivary Glands . . . . . . 664
Merton R. Bernfield and
Shib D. Banerjee and
Ronald H. Cohn Dependence of Salivary Epithelial
Morphology and Branching Morphogenesis
Upon Acid Mucopolysaccharide-Protein
(Proteoglycan) at the Epithelial Surface 674
Carrick E. Devine and
Avril V. Somlyo and
Andrew P. Somlyo Sarcoplasmic Reticulum and
Excitation-Contraction Coupling in
Mammalian Smooth Muscles . . . . . . . . 690
Thomas L. Lentz Distribution of Leucine-$^3$H During
Axoplasmic Transport Within Regenerating
Neurons As Determined by
Electron-Microscope Radioautography . . 719
Owen Black and
Edward Bresnick Ontogenetic Changes of Proteins of
Endoplasmic Reticulum . . . . . . . . . 733
M. K. Raizada and
C. R. Krishna Murti Transformation of Trophic Hartmannella
Culbertsoni into Viable Cysts by Cyclic
3',5'-Adenosine Monophosphate . . . . . 743
Samuel Dales Concerning the Universality of a
Microtubule Antigen in Animal Cells . . 748
Joseph McGuire and
Gisela Moellmann and
Frank McKeon Cytochalasin B and Pigment Granule
Translocation . . . . . . . . . . . . . 754
R. Scharff and
R. W. Hendler and
N. Nanninga and
A. H. Burgess Respiration and Protein Synthesis in
\bionameEscherichia coli
Membrane-Envelope Fragments . . . . . . 1
Donald L. Price and
Keith R. Porter The Response of Ventral Horn Neurons to
Axonal Transection . . . . . . . . . . . 24
Susannah T. Rohrlich and
Keith R. Porter Fine Structural Observations Relating to
the Production of Color by the
Iridophores of a Lizard, Anolis
Carolinensis . . . . . . . . . . . . . . 38
Ernest W. April and
Philip W. Brandt and
Gerald F. Elliott The Myofilament Lattice: Studies on
Isolated Fibers . . . . . . . . . . . . 53
W. E. Cassady and
E. H. Leiter and
A. Bergquist and
R. P. Wagner Separation of Mitochondrial Membranes of
Neurospora Crassa . . . . . . . . . . . 66
L. Andrew Staehelin and
Francis J. Chlapowski and
Mary A. Bonneville Lumenal Plasma Membrane of the Urinary
Bladder . . . . . . . . . . . . . . . . 73
Francis J. Chlapowski and
Mary A. Bonneville and
L. Andrew Staehelin Lumenal Plasma Membrane of the Urinary
Bladder . . . . . . . . . . . . . . . . 92
Donald J. Cummings Isolation and Partial Characterization
of Macro- and Micronuclei from
Paramecium Aurelia . . . . . . . . . . . 105
Helmut Plattner and
Walter M. Fischer and
Werner W. Schmitt and
Luis Bachmann Freeze Etching of Cells Without
Cryoprotectants . . . . . . . . . . . . 116
Mary E. King and
Gabriel C. Godman and
Donald W. King Respiratory Enzymes and Mitochondrial
Morphology of HeLa and L Cells Treated
with Chloramphenicol and Ethidium
Bromide . . . . . . . . . . . . . . . . 127
Brian E. Gilbert and
Terry C. Johnson Protein Turnover During Maturation of
Mouse Brain Tissue . . . . . . . . . . . 143
Daniel S. Friend and
Norton B. Gilula A Distinctive Cell Contact in the Rat
Adrenal Cortex . . . . . . . . . . . . . 148
Mathew P. Daniels Colchicine Inhibition of Nerve Fiber
Formation in Vitro . . . . . . . . . . . 164
George L. Eliceiri The Ribosomal RNA of Hamster-Mouse
Hybrid Cells . . . . . . . . . . . . . . 177
Matthew M. LaVail and
Richard L. Sidman and
Deborah O'Neil Photoreceptor-Pigment Epithelial Cell
Relationships in Rats with Inherited
Retinal Degeneration . . . . . . . . . . 185
S. G. Waxman and
G. D. Pappas and
M. V. L. Bennett Morphological Correlates of Functional
Differentiation of Nodes of Ranvier
Along Single Fibers in the Neurogenic
Electric Organ of the Knife Fish
Sternarchus . . . . . . . . . . . . . . 210
A. F. Hopper and
P. M. Rose and
R. W. Wannemacher Cell Population Changes in the
Intestinal Mucosa of Protein-Depleted Or
Starved Rats . . . . . . . . . . . . . . 225
C. A. Pasternak Relief from Contact Inhibition . . . . . 231
Camillo Peracchia and
Brant S. Mittler Fixation by Means of
Glutaraldehyde-Hydrogen Peroxide
Reaction Products . . . . . . . . . . . 234
A. L. Kierszenbaum and
Laura L. Tres and
C. J. Tandler The Distribution of Inorganic Cations
During Spermiogenesis in the Mouse . . . 239
Richard F. Baker Fusion of Human Red Blood Cell Membranes 244
C. Meban Localization of Phosphatidic Acid
Phosphatase Activity in Granular
Pneumonocytes . . . . . . . . . . . . . 249
Martin Hagopian and
Eladio A. Nunez Sarcolemmal Scalloping at Short
Sarcomere Lengths with Incidental
Observations on the T Tubules . . . . . 252
Robert E. Hinkley and
Frederick E. Samson Anesthetic-Induced Transformation of
Axonal Microtubules . . . . . . . . . . 258
F. Rudolf Turner Modified Microtubules in the Testis of
the Water Strider, Gerris Remigis (Say) 263
Constantino Sotelo and
Rodolfo Llinás Specialized Membrane Junctions Between
Neurons in the Vertebrate Cerebellar
Cortex . . . . . . . . . . . . . . . . . 271
J. David Castle and
James D. Jamieson and
George E. Palade Radioautographic Analysis of the
Secretory Process in the Parotid Acinar
Cell of the Rabbit . . . . . . . . . . . 290
Phyllis R. Strauss Acriflavin Resistance in the
Hemoflagellate, Leishmania Tarentolae 312
H. J. Mersmann and
J. Goodman and
J. M. Houk and
S. Anderson Studies on the Biochemistry of
Mitochondria and Cell Morphology in the
Neonatal Swine Hepatocyte . . . . . . . 335
Bruce H. Lipton and
Irwin R. Konigsberg A Fine-Structural Analysis of the Fusion
of Myogenic Cells . . . . . . . . . . . 348
Nicolae Simionescu and
Maia Simionescu and
George E. Palade Permeability of Intestinal Capillaries 365
David R. Wolstenholme and
Robert G. Kirschner and
Nicholas J. Gross Heat Denaturation Studies of Rat Liver
Mitochondrial DNA . . . . . . . . . . . 393
B. Lambert and
L. Wieslander and
B. Daneholt and
E. Egyházi and
U. Ringborg In Situ Demonstration of DNA Hybridizing
with Chromosomal and Nuclear Sap RNA in
Chironomus Tentans . . . . . . . . . . . 407
Thomas E. Schroeder The Contractile Ring . . . . . . . . . . 419
Irving Goldschneider and
A. A. Moscona Tissue-Specific Cell-Surface Antigens in
Embryonic Cells . . . . . . . . . . . . 435
Charles R. Hackenbrock Energy-Linked Ultrastructural
Transformations in Isolated Liver
Mitochondria and Mitoplasts . . . . . . 450
Steven A. Rosenberg and
Albert B. Einstein Sialic Acids on the Plasma Membrane of
Cultured Human Lymphoid Cells . . . . . 466
Bruce P. Brandhorst and
Tom Humphreys Stabilities of Nuclear and Messenger RNA
Molecules in Sea Urchin Embryos . . . . 474
Laura L. Tres and
A. L. Kierszenbaum and
C. J. Tandler Inorganic Cations in the Cell Nucleus 483
Norton B. Gilula and
Peter Satir The Ciliary Necklace . . . . . . . . . . 494
Lynette Feeney and
Steven L. Wissig A Biochemical and Radioautographic
Analysis of Protein Secretion by Thyroid
Lobes Incubated in Vitro . . . . . . . . 510
E. Egyházi and
B. D'Monte and
J.-E. Edström Effects of $ \alpha $-amanitin on in
vitro labeling of RNA from defined
nuclear components in salivary gland
cells from \bionameChironomus tentans 523
Phyllis M. Novikoff and
Alex B. Novikoff Peroxisomes in Absorptive Cells of
Mammalian Small Intestine . . . . . . . 532
David M. Phillips Comparative Analysis of Mammalian Sperm
Motility . . . . . . . . . . . . . . . . 561
G. T. O'Loughlin and
T. C. Chambers Extracellular Microtubules in the Aphid
Gut . . . . . . . . . . . . . . . . . . 575
P. F. Baker and
Anne E. Warner Intracellular Calcium and Cell Cleavage
in Early Embryos of \bionameXenopus
Laevis . . . . . . . . . . . . . . . . . 579
S. S. Spicer and
B. J. Martin and
J. V. Simson The Junctional Complex Associated Body
of Human Eccrine Sweat Gland . . . . . . 582
Joshua R. Sanes and
Lawrence M. Okun Induction of DNA Synthesis in Cultured
Neurons by Ultraviolet Light Or Methyl
Methane Sulfonate . . . . . . . . . . . 587
Thomas W. O'Brien Occurrence of Active 80 S Ribosomes in
Subcellular Particles in the
Mitochondrial Fraction of Fetal Bovine
Liver . . . . . . . . . . . . . . . . . 590
Jerry E. Manning and
David R. Wolstenholme and
Oliver C. Richards Circular DNA Molecules Associated with
Chloroplasts of Spinach, Spinacia
Oleracea . . . . . . . . . . . . . . . . 594
Thomas S. Lecount and
Robert D. Grey Transient Shortening of Microvilli
Induced by Cycloheximide in the Duodenal
Epithelium of the Chicken . . . . . . . 601
James N. Dumont and
R. A. Wallace The Effects of Vinblastine on Isolated
\bionameXenopus Oocytes . . . . . . . . 605
Stephanie Gordon Phillips Repopulation of the Postmitotic
Nucleolus by Preformed RNA . . . . . . . 611
William R. Jeffery Evidence for a Temporal Incompatibility
Between DNA Replication and Division
During the Cell Cycle of
\bionameTetrahymena . . . . . . . . . . 624
Beatriz G. T. Pogo Early Events in Lymphocyte
Transformation by Phytohemagglutinin . . 635
C. R. Hopkins The Biosynthesis, Intracellular
Transport, and Packaging of
Melanocyte-Stimulating Peptides in the
Amphibian Pars Intermedia . . . . . . . 642
Fritz A. Henn and
Hans-Arne Hansson and
Anders Hamberger Preparation of Plasma Membrane from
Isolated Neurons . . . . . . . . . . . . 654
V. Herzog and
F. Miller The Localization of Endogenous
Peroxidase in the Lacrimal Gland of the
Rat During Postnatal Development . . . . 662
Blair Bowers and
Thomas E. Olszewski Pinocytosis in \bionameAcanthamoeba
Castellanii . . . . . . . . . . . . . . 681
Gary G. Leppard and
J. Ross Colvin Electron-Opaque Fibrils and Granules in
and Between the Cell Walls of Higher
Plants . . . . . . . . . . . . . . . . . 695
Charles E. Stirling Radioautographic Localization of Sodium
Pump Sites in Rabbit Intestine . . . . . 704
Donald E. Olins and
Ada L. Olins Physical Studies of Isolated Eucaryotic
Nuclei . . . . . . . . . . . . . . . . . 715
Eugene A. Arnold and
David H. Yawn and
David G. Brown and
Robert C. Wyllie and
Donald S. Coffey Structural Alteration in Isolated Rat
Liver Nuclei After Removal of Template
Restriction by Polyanions . . . . . . . 737
Daniel S. Friend and
Norton B. Gilula Variations in Tight and Gap Junctions in
Mammalian Tissues . . . . . . . . . . . 758
Pedro Pinto da Silva Translational Mobility of the Membrane
Intercalated Particles of Human
Erythrocyte Ghosts . . . . . . . . . . . 777
Daniel G. Wright and
Stephen E. Malawista The Mobilization and Extracellular
Release of Granular Enzymes from Human
Leukocytes During Phagocytosis . . . . . 788
Roch Bernier and
Roberto Iglesias and
René Simard Detection of DNA by Tritiated
Actinomycin D on Ultrathin Frozen
Sections . . . . . . . . . . . . . . . . 798
P. S. Vassar and
J. M. Hards and
D. E. Brooks and
B. Hagenberger and
G. V. F. Seaman Physicochemical Effects of Aldehydes on
the Human Erythrocyte . . . . . . . . . 809
D. Montgomery Bissell and
Jeremiah G. Tilles Radioimmunoassay of Serum Albumin
Produced by Human Embryonic Liver in
Monolayer Culture . . . . . . . . . . . 819
Werner W. Franke and
Ulrich Scheer and
Hansjörg Fritsch Intranuclear and Cytoplasmic Annulate
Lamellae in Plant Cells . . . . . . . . 823
Tom Brady and
Mary E. Clutter Cytolocalization of Ribosomal Cistrons
in Plant Polytene Chromosomes . . . . . 827
Milan Potmesil and
Anna Goldfeder Nucleolar Morphology and Maturation of
Thymic Lymphocytes . . . . . . . . . . . 832
Joan B. Peterson and
Robert H. Gray and
Hans Ris Meiotic Spindle Plaques in
\bionameSaccharomyces Cerevisiae . . . . 837
Harold C. Slavkin and
Richard Croissant and
Pablo Bringas Epithelial-Mesenchymal Interactions
During Odontogenesis . . . . . . . . . . 841
Yasuo Uehara and
Geoffrey Burnstock Postsynaptic Specialization of Smooth
Muscle at Close Neuromuscular Junctions
in the Guinea Pig Sphincter Pupillae . . 849
Taisuke Nakao Fusion of Unit Membranes of the
Endoplasmic Reticulum in the Gill
Epithelial Cell of Shrimp, Caridina . . 853
Ronald H. Stevens and
Harold Amos RNA Metabolism in HeLa Cells at Reduced
Temperature . . . . . . . . . . . . . . 1
A. Adoutte and
M. Balmefrézol and
J. Beisson and
J. André The Effects of Erythromycin and
Chloramphenicol on the Ultrastructure of
Mitochondria in Sensitive and Resistant
Strains of Paramecium . . . . . . . . . 8
J. B. Rattner Observations of Centriole Formation in
Male Meiosis . . . . . . . . . . . . . . 20
B. Ceccarelli and
W. P. Hurlbut and
A. Mauro Depletion of Vesicles from Frog
Neuromuscular Junctions by Prolonged
Tetanic Stimulation . . . . . . . . . . 30
Sidney L. Tamm Free Kinetosomes in Australian
Flagellates . . . . . . . . . . . . . . 39
Paul M. Lizardi and
David J. L. Luck The Intracellular Site of Synthesis of
Mitochondrial Ribosomal Proteins in
Neurospora Crassa . . . . . . . . . . . 56
Barbara H. Gibbons and
I. R. Gibbons Flagellar Movement and Adenosine
Triphosphatase Activity in Sea Urchin
Sperm Extracted with Triton X-100 . . . 75
Helen K. Hagopian and
Judith A. Lippke and
Vernon M. Ingram Erythropoietic Cell Cultures from Chick
Embryos . . . . . . . . . . . . . . . . 98
D. Montgomery Bissell and
Lydia Hammaker and
Rudi Schmid Liver Sinusoidal Cells . . . . . . . . . 107
Sei-Ichi Matsui and
Hiroshi Yoshida and
Herbert Weinfeld and
Avery A. Sandberg Induction of Prophase in Interphase
Nuclei by Fusion with Metaphase Cells 120
Ralph Nachman and
James G. Hirsch and
Marco Baggiolini Studies on Isolated Membranes of
Azurophil and Specific Granules from
Rabbit Polymorphonuclear Leukocytes . . 133
Marilyn G. Farquhar and
Dorothy F. Bainton and
Marco Baggiolini and
Christian de Duve Cytochemical Localization of Acid
Phosphatase Activity in Granule
Fractions from Rabbit Polymorphonuclear
Leukocytes . . . . . . . . . . . . . . . 141
John A. Williams and
J. Wolff Colchicine-Binding Protein and the
Secretion of Thyroid Hormone . . . . . . 157
Mark Nameroff Contact-Mediated Reversible Suppression
of Myogenesis . . . . . . . . . . . . . 166
Richard G. Kulka and
Gordon M. Tomkins and
Richard B. Crook Clonal Differences in Glutamine
Synthetase Activity of Hepatoma Cells 175
Earl Ettienne Subcellular Localization of Calcium
Repositories in Plasmodia of the
Acellular Slime Mold \bionamePhysarum
Polycephalum . . . . . . . . . . . . . . 179
Susan Drury Waaland and
J. Robert Waaland and
Robert Cleland A New Pattern of Plant Cell Elongation:
Bipolar Band Growth . . . . . . . . . . 184
D. K. Jasper and
J. R. Bronk Polar Distribution of Intramitochondrial
Granules of Mucosal Epithelial Cells . . 190
W. A. Walker and
R. Cornell and
L. M. Davenport and
K. J. Isselbacher Macromolecular Absorption . . . . . . . 195
Jean-Claude Wanson and
Pierre Drochmans Role of the Sarcoplasmic Reticulum in
Glycogen Metabolism . . . . . . . . . . 206
Dominic M. K. Lam The Biosynthesis and Content of
Gamma-Aminobutyric Acid in the Goldfish
Retina . . . . . . . . . . . . . . . . . 225
Hans-G Heidrich and
Rolf Kinne and
Eva Kinne-Saffran and
Kurt Hannig The Polarity of the Proximal Tubule Cell
in Rat Kidney . . . . . . . . . . . . . 232
Richard G. W. Anderson The Three-Dimensional Structure of the
Basal Body from the Rhesus Monkey
Oviduct . . . . . . . . . . . . . . . . 246
Richard C. Weisenberg Changes in the Organization of Tubulin
During Meiosis in the Eggs of the Surf
Clam, Spisula Solidissima . . . . . . . 266
David C. Shephard and
Wendy B. Levin Biosynthesis in Isolated Acetabularia
Chloroplasts . . . . . . . . . . . . . . 279
R. Tanguay and
K. D. Chaudhary Studies on Mitochondria . . . . . . . . 295
Terry E. Machen and
David Erlij and
F. B. P. Wooding Permeable Junctional Complexes . . . . . 302
E. Gantt and
C. A. Lipschultz Phycobilisomes of Porphyridium Cruentum 313
Adrian R. L. Gear and
Jana M. Bednarek Direct Counting and Sizing of
Mitochondria in Solution . . . . . . . . 325
Hartmut C. Renger and
David R. Wolstenholme The Form and Structure of Kinetoplast
DNA of Crithidia . . . . . . . . . . . . 346
I. R. Gibbons and
E. Fronk Some Properties of Bound and Soluble
Dynein from Sea Urchin Sperm Flagella 365
James E. Bourdeau and
Frank A. Carone and
Charles E. Ganote Serum Albumin Uptake in Isolated
Perfused Renal Tubules . . . . . . . . . 382
J. Ramus and
S. T. Groves Incorporation of Sulfate into the
Capsular Polysaccharide of the Red Alga
Porphyridium . . . . . . . . . . . . . . 399
Tito Cavallo and
Robert Sade and
Judah Folkman and
Ramzi S. Cotran Tumor Angiogenesis . . . . . . . . . . . 408
A. G. Gambarini and
R. Meneghini Ribosomal RNA Genes in Salivary Gland
and Ovary of Rhynchosciara Angelae . . . 421
Robert J. Chertok and
Suzanne Lake A Simple Method for the Preparation of
Renal Brush Borders . . . . . . . . . . 426
Kenneth D. Stewart and
Gary L. Floyd and
Karl R. Mattox and
Melanie E. Davis Cytochemical Demonstration of a Single
Peroxisome in a Filamentous Green Alga 431
Roger F. Searle Observations on the Unusual Cytoplasmic
Lacunae of the Porcine Hepatocyte . . . 434
G. A. Langer and
J. S. Frank Lanthanum in Heart Cell Culture . . . . 441
Judy M. Strum and
Alain F. Junod Radioautographic Demonstration of
$5$-Hydroxytryptamine-$^3$H Uptake by
Pulmonary Endothelial Cells . . . . . . 456
Pierre V. Vignais and
Barbara J. Stevens and
Janine Huet and
Jean André Mitoribosomes from Candida Utilis . . . 468
Edward Aiello and
Michael A. Sleigh The Metachronal Wave of Lateral Cilia of
Mytilus Edulis . . . . . . . . . . . . . 493
G. B. Witman and
K. Carlson and
J. Berliner and
Joel L. Rosenbaum Chlamydomonas Flagella . . . . . . . . . 507
G. B. Witman and
K. Carlson and
Joel L. Rosenbaum Chlamydomonas Flagella . . . . . . . . . 540
N. Umiel and
W. Plaut Interaction of Poly-L-Lysine with
Chromatin . . . . . . . . . . . . . . . 556
Jack Rosenbluth Myoneural Junctions of Two
Ultrastructurally Distinct Types in
Earthworm Body Wall Muscle . . . . . . . 566
Giuseppina Barsacchi and
Joseph G. Gall Chromosomal Localization of Repetitive
DNA in the Newt, Triturus . . . . . . . 580
David C. Swinton and
Philip C. Hanawalt In Vivo Specific Labeling of
Chlamydomonas Chloroplast DNA . . . . . 592
Jerry W. Shay Electron Microscope Studies of
Spermatozoa of Rhynchosciara Sp . . . . 598
Samuel B. Horowitz The Permeability of the Amphibian Oocyte
Nucleus, in Situ . . . . . . . . . . . . 609
Tom Elsdale and
Jonathan Bard Collagen Substrata for Studies on Cell
Behavior . . . . . . . . . . . . . . . . 626
Robert A. Tobey and
Harry A. Crissman and
Paul M. Kraemer A Method for Comparing Effects of
Different Synchronizing Protocols on
Mammalian Cell Cycle Traverse . . . . . 638
Daniel A. Goodenough and
Walther Stoeckenius The Isolation of Mouse Hepatocyte Gap
Junctions . . . . . . . . . . . . . . . 646
Awtar Krishan Cytochalasin-B: Time-Lapse
Cinematographic Studies on Its Effects
on Cytokinesis . . . . . . . . . . . . . 657
H. Ono and
S. Kobayashi and
K. Yanagisawa Cell Fusion in the Cellular Slime Mold,
\bionameDictyostelium Discoideum . . . . 665
Jacopo Meldolesi and
Dario Cova Composition of Cellular Membranes in the
Pancreas of the Guinea Pig . . . . . . . 1
Jeffrey E. Froehlich and
Martin Rachmeler Effect of Adenosine 3'-5'-Cyclic
Monophosphate on Cell Proliferation . . 19
Leonard Mindich and
Samuel Dales Membrane Synthesis in Bacillus Subtilis 32
Asish C. Nag Ultrastructure and Adenosine
Triphosphatase Activity of Red and White
Muscle Fibers of the Caudal Region of a
Fish, Salmo Gairdneri . . . . . . . . . 42
James L. Oschman and
Betty J. Wall Calcium Binding to Intestinal Membranes 58
Brian L. Kotzin and
Robert F. Baker Selective Inhibition of Genetic
Transcription in Sea Urchin Embryos . . 74
Joram Piatigorsky and
Henry deF. Webster and
Miriam Wollberg Cell Elongation in the Cultured
Embryonic Chick Lens Epithelium with and
Without Protein Synthesis . . . . . . . 82
Thomas L. Lentz Development of the Neuromuscular
Junction . . . . . . . . . . . . . . . . 93
Ariane Monneron and
Günter Blobel and
George E. Palade Fractionation of the Nucleus by Divalent
Cations . . . . . . . . . . . . . . . . 104
Maria C. Magalhães A New Crystal-Containing Cell in Human
Adrenal Cortex . . . . . . . . . . . . . 126
Sara E. Zalik and
Vi Scott Cell Surface Changes During
Dedifferentiation in the Metaplastic
Transformation of Iris into Lens . . . . 134
H. Bruce Bosmann and
Marjorie W. Myers and
Delena Dehond and
Richard Ball and
Kenneth R. Case Mitochondrial Autonomy . . . . . . . . . 147
Peter G. W. Plagemann and
John Erbe Thymidine Transport by Cultured Novikoff
Hepatoma Cells and Uptake by Simple
Diffusion and Relationship to
Incorporation into Deoxyribonucleic Acid 161
Peter G. W. Plagemann and
Richard D. Estensen Cytochalasin B . . . . . . . . . . . . . 179
Ralph M. Steinman and
Zanvil A. Cohn The Interaction of Soluble Horseradish
Peroxidase with Mouse Peritoneal
Macrophages in Vitro . . . . . . . . . . 186
Dale Purves and
Uel J. McMahan The Distribution of Synapses on a
Physiologically Identified Motor Neuron
in the Central Nervous System of the
Leech . . . . . . . . . . . . . . . . . 205
Rhea J. C. Levine and
Maynard M. Dewey and
George W. de Villafranca Immunohistochemical Localization of
Contractile Proteins in Limulus Striated
Muscle . . . . . . . . . . . . . . . . . 221
Raymond J. Lasek and
Carolyn K. Lee and
Ronald J. Przybylski Granular Extensions of the Nucleoli in
Giant Neurons of \bionameAplysia
Californica . . . . . . . . . . . . . . 237
David A. Warner and
James F. Perdue Cytochalasin B and the Adenosine
Triphosphate Content of Treated
Fibroblasts . . . . . . . . . . . . . . 242
Lelio Orci and
Alain Perrelet and
Arthur A. Like Fenestrae in the Rough Endoplasmic
Reticulum of the Exocrine Pancreatic
Cells . . . . . . . . . . . . . . . . . 245
Sidney L. Tamm Ciliary Motion in Paramecium . . . . . . 250
Hans J. Leenders and
Pieter J. A. Beckers The Effect of Changes in the Respiratory
Metabolism Upon Genome Activity . . . . 257
Richard W. Hendler and
Amelia H. Burgess Respiration and Protein Synthesis in
\bionameEscherichia coli
Membrane-Envelope Fragments . . . . . . 266
Joan A. Higgins and
Russell J. Barrnett Studies on the Biogenesis of Smooth
Endoplasmic Reticulum Membranes in
Livers of Phenobarbital-Treated Rats . . 282
Stanley G. Sawicki and
Gabriel C. Godman On the Recovery of Transcription After
Inhibition by Actinomycin D . . . . . . 299
Mac Donald Cave Localization of Ribosomal DNA Within
Oocytes of the House Cricket, Acheta
Domesticus (Orthoptera: Gryllidae) . . . 310
Thoru Pederson and
Elliott Robbins Chromatin Structure and the Cell
Division Cycle . . . . . . . . . . . . . 322
Wayne Hohman and
Harald Schraer Low Temperature Ultramicroincineration
of Thin-Sectioned Tissue . . . . . . . . 328
James E. Haber and
John G. Peloquin and
Harlyn O. Halvorson and
Gary G. Borisy Colcemid Inhibition of Cell Growth and
the Characterization of a
Colcemid-Binding Activity in
\bionameSaccharomyces Cerevisiae . . . . 355
James R. Aist and
P. H. Williams Ultrastructure and Time Course of
Mitosis in the Fungus Fusarium Oxysporum 368
Ann L. Hubbard and
Zanvil A. Cohn The Enzymatic Iodination of the Red Cell
Membrane . . . . . . . . . . . . . . . . 390
Rudolf Vracko and
Earl P. Benditt Basal Lamina: the Scaffold for Orderly
Cell Replacement . . . . . . . . . . . . 406
Anita C. Been and
Ellen M. Rasch Cellular and Secretory Proteins of the
Salivary Glands of Sciara Coprophila
During the Larval-Pupal Transformation 420
Gerd G. Maul and
Helmut M. Maul and
Joseph E. Scogna and
Michael W. Lieberman and
Gary S. Stein and
Betty Yee-Li Hsu and
Thaddeus W. Borun Time Sequence of Nuclear Pore Formation
in Phytohemagglutinin-Stimulated
Lymphocytes and in HeLa Cells During the
Cell Cycle . . . . . . . . . . . . . . . 433
Brian Burchell and
Geoffrey J. Dutton and
Andrew M. Nemeth Development of Phenobarbital-Sensitive
Control Mechanisms for Uridine
Diphosphate Glucuronyltransferase
Activity in Chick Embryo Liver . . . . . 448
Nicholas E. Weber Ultrastructural Studies of Beef Heart
Mitochondria . . . . . . . . . . . . . . 457
Jeanine-Anne Heuson-Stiennon and
Jean-Claude Wanson and
Pierre Drochmans Isolation and Characterization of the
Sarcoplasmic Reticulum of Skeletal
Muscle . . . . . . . . . . . . . . . . . 471
James Bearden and
Irwin J. Bendet Birefringence of Spermatozoa . . . . . . 489
Irwin J. Bendet and
James Bearden Birefringence of Spermatozoa . . . . . . 501
Frederick B. Merk and
N. Scott McNutt Nexus Junctions Between Dividing and
Interphase Granulosa Cells of the Rat
Ovary . . . . . . . . . . . . . . . . . 511
Beatriz G. T. Pogo Specific Inhibition by Rifampicin of
Transcription in Human Lymphocytes
Stimulated by Phytohemagglutinin . . . . 515
S. Bullivant and
D. G. Rayns and
W. S. Bertaud and
J. P. Chalcroft and
G. F. Grayston Freeze-Fractured Myosin Filaments . . . 520
J. M. Sturgess and
F. A. de la Iglesia Morphometry of the Golgi Apparatus in
Developing Liver . . . . . . . . . . . . 524
G. Tripodi and
P. Pizzolongo and
M. Giannattasio A DNase-Sensitive Twisted Structure in
the Mitochondrial Matrix of
\bionamePolysiphonia (Rhodophyta) . . . 530
Bela J. Gulyas The Rabbit Zygote . . . . . . . . . . . 533
Peter B. Armstrong and
David Parenti Cell Sorting in the Presence of
Cytochalasin B . . . . . . . . . . . . . 542
Anna M. Novi and
Renato Baserga Changes in Chromatin Template Activity
and Their Relationship to DNA Synthesis
in Mouse Parotid Glands Stimulated by
Isoproterenol . . . . . . . . . . . . . 554
Joyce E. Purdy and
Melvyn Lieberman and
Anne E. Roggeveen and
R. Gary Kirk Synthetic Strands of Cardiac Muscle . . 563
David A. Wolff and
HÅkan Pertoft Separation of HeLa Cells by Colloidal
Silica Density Gradient Centrifugation 579
F. Sreter and
S. Holtzer and
J. Gergely and
H. Holtzer Some Properties of Embryonic Myosin . . 586
Alain Perrelet Protein Synthesis in the Visual Cells of
the Honeybee Drone As Studied with
Electron Microscope Radioautography . . 595
Malcolm S. Steinberg and
Lawrence L. Wiseman Do Morphogenetic Tissue Rearrangements
Require Active Cell Movements? . . . . . 606
Ralph M. Steinman and
Zanvil A. Cohn The Interaction of Particulate
Horseradish Peroxidase (Hrp)-Anti Hrp
Immune Complexes with Mouse Peritoneal
Macrophages in Vitro . . . . . . . . . . 616
Daniel V. Kimberg and
John N. Loeb Effects of Cortisone Administration on
Rat Liver Mitochondria . . . . . . . . . 635
Alan E. Organ and
Eugene C. Bovee and
Theodore L. Jahn The Mechanism of the Water Expulsion
Vesicle of the Ciliate
\bionameTetrahymena Pyriformis . . . . . 644
M. Paul and
M. R. Goldsmith and
J. R. Hunsley and
F. C. Kafatos Specific Protein Synthesis in Cellular
Differentiation . . . . . . . . . . . . 653
Barbra L. Eaton and
Frank A. Pepe M Band Protein . . . . . . . . . . . . . 681
Carl W. Cotman and
Dwan Taylor Isolation and Structural Studies on
Synaptic Complexes from Rat Brain . . . 696
Paul M. Kraemer and
Robert A. Tobey Cell-Cycle Dependent Desquamation of
Heparan Sulfate from the Cell Surface 713
Roy Peach Nematosomes in the Rat Trigeminal
Ganglion . . . . . . . . . . . . . . . . 718
Kenneth Watson The Organization of Ribosomal Granules
Within Mitochondrial Structures of
Aerobic and Anaerobic Cells of
\bionameSaccharomyces Cerevisiae . . . . 721
J. Kenneth Hoober and
William J. Stegeman Control of the Synthesis of a Major
Polypeptide of Chloroplast Membranes in
Chlamydomonas Reinhardi . . . . . . . . 1
Mark S. Mooseker and
Lewis G. Tilney Isolation and Reactivation of the
Axostyle . . . . . . . . . . . . . . . . 13
Ronald R. Minor Somite Chondrogenesis . . . . . . . . . 27
Clinton D. Stoner and
Howard D. Sirak Adenine Nucleotide-Induced Contraction
of the Inner Mitochondrial Membrane . . 51
Clinton D. Stoner and
Howard D. Sirak Adenine Nucleotide-Induced Contraction
of the Inner Mitochondrial Membrane . . 65
Graham Hoyle and
Patricia A. McNeill and
Allen I. Selverston Ultrastructure of Barnacle Giant Muscle
Fibers . . . . . . . . . . . . . . . . . 74
Guido Zampighi and
J. David Robertson Fine Structure of the Synaptic Discs
Separated from the Goldfish Medulla
Oblongata . . . . . . . . . . . . . . . 92
Donald Orlic and
Robert Lev Fetal Rat Intestinal Absorption of
Horseradish Peroxidase from Swallowed
Amniotic Fluid . . . . . . . . . . . . . 106
Clara Franzini-Armstrong Studies of the Triad . . . . . . . . . . 120
Gary E. Wise and
Lester Goldstein Electron Microscope Localization of
Nuclear RNA's That Shuttle Between
Cytoplasm and Nucleus and Nuclear RNA's
That Do Not . . . . . . . . . . . . . . 129
N. Umiel and
W. Plaut Interaction of Poly-L-Lysine with
Chromatin . . . . . . . . . . . . . . . 139
Alberto J. Solari and
Montrose J. Moses The Structure of the Central Region in
the Synaptonemal Complexes of Hamster
and Cricket Spermatocytes . . . . . . . 145
Birgit Satir and
Caroline Schooley and
Peter Satir Membrane Fusion in a Model System . . . 153
U. Oron and
A. Bdolah Regulation of Protein Synthesis in the
Venom Gland of Viperid Snakes . . . . . 177
M. R. Adelman and
Gunter Blobel and
David D. Sabatini An Improved Cell Fractionation Procedure
for the Preparation of Rat Liver
Membrane-Bound Ribosomes . . . . . . . . 191
M. R. Adelman and
David D. Sabatini and
Günter Blobel Ribosome-Membrane Interaction . . . . . 206
David R. Wolstenholme and
Katsuro Koike and
Patricia Cochran-Fouts Single Strand-Containing Replicating
Molecules of Circular Mitochondrial DNA 230
David R. Wolstenholme and
John D. McLaren and
Katsuro Koike and
Elaine L. Jacobson Catenated Oligomeric Circular DNA
Molecules from Mitochondria of Malignant
and Normal Mouse and Rat Tissues . . . . 247
Howard G. Sachs and
Terence F. McDonald and
Robert L. DeHaan Tetrodotoxin Sensitivity of Cultured
Embryonic Heart Cells Depends on Cell
Interactions . . . . . . . . . . . . . . 255
Gail Stetten and
Seymour Lederberg Colcemid Sensitivity of Fission Yeast 259
Tomasz J. Wodzicki and
Walter J. Humphreys Maturing Pine Tracheids . . . . . . . . 263
Bernard Tandler and
Charles L. Hoppel Division of Giant Mitochondria During
Recovery from Cuprizone Intoxication . . 266
Joseph W. DePierre and
Manfred L. Karnovsky Plasma Membranes of Mammalian Cells . . 275
J. Richard McIntosh and
Edward S. Ogata and
Story C. Landis The Axostyle of Saccinobaculus . . . . . 304
J. Richard McIntosh The Axostyle of Saccinobaculus . . . . . 324
G. Benjamin Bouck and
David L. Brown Microtubule Biogenesis and Cell Shape in
Ochromonas . . . . . . . . . . . . . . . 340
David L. Brown and
G. Benjamin Bouck Microtubule Biogenesis and Cell Shape in
Ochromonas . . . . . . . . . . . . . . . 360
Michael S. Jensen and
Dorothy F. Bainton Temporal Changes in pH Within the
Phagocytic Vacuole of the
Polymorphonuclear Neutrophilic Leukocyte 379
Juan I. Korenbrot and
Dennis T. Brown and
Richard A. Cone Membrane Characteristics and Osmotic
Behavior of Isolated Rod Outer Segments 389
Fredric S. Fay and
P. H. Cooke Reversible Disaggregation of
Myofilaments in Vertebrate Smooth Muscle 399
N. Scott McNutt and
Lloyd A. Culp and
Paul H. Black Contact-Inhibited Revertant Cell Lines
Isolated from Sv40-Transformed Cells . . 412
Russell Meints and
Eugene Goldwasser The Persistence of Hemopoietic Stem
Cells in Vitro . . . . . . . . . . . . . 429
Irving Finger and
Patricia Lavanchy and
Ann Meany Synthesis of Paramecium Surface Proteins 434
Norman E. Williams and
Joseph Frankel Regulation of Microtubules in
\bionameTetrahymena . . . . . . . . . . 441
Norman E. Williams and
E. Marlo Nelsen Regulation of Microtubules in
\bionameTetrahymena . . . . . . . . . . 458
R. Bruce Szamier and
Michael V. L. Bennett Rapid Degeneration of Ampullary
Electroreceptor Organs After Denervation 466
Asao Hirano and
Herbert M. Dembitzer Cerebellar Alterations in the Weaver
Mouse . . . . . . . . . . . . . . . . . 478
William J. Grimes and
Judith L. Schroeder Dibutyryl Cyclic Adenosine 3' 5'
Monophosphate, Sugar Transport, and
Regulatory Control of Cell Division in
Normal and Transformed Cells . . . . . . 487
Una Smith and
J. W. Ryan and
D. S. Smith Freeze-Etch Studies of the Plasma
Membrane of Pulmonary Endothelial Cells 492
Peter J. Gruber and
Wayne M. Becker and
Eldon H. Newcomb The Development of Microbodies and
Peroxisomal Enzymes in Greening Bean
Leaves . . . . . . . . . . . . . . . . . 500
P. Seeman and
D. Cheng and
G. H. Iles Structure of Membrane Holes in Osmotic
and Saponin Hemolysis . . . . . . . . . 519
G. H. Iles and
P. Seeman and
D. Naylor and
B. Cinader Membrane Lesions in Immune Lysis . . . . 528
Susan J. Abrahams and
Eric Holtzman Secretion and Endocytosis in
Insulin-Stimulated Rat Adrenal Medulla
Cells . . . . . . . . . . . . . . . . . 540
Richard D. Allen Structures Linking the Myonemes,
Endoplasmic Reticulum, and Surface
Membranes in the Contractile Ciliate
Vorticella . . . . . . . . . . . . . . . 559
Mary Lake Polan and
Susan Friedman and
Joseph G. Gall and
Walter Gehring Isolation and Characterization of
Mitochondrial DNA from
\bionameDrosophila Melanogaster . . . . 580
Robert B. Low and
Alfred L. Goldberg Nonuniform Rates of Turnover of
Myofibrillar Proteins in Rat Diaphragm 590
Paul H. Jewett and
Stephen D. Leonard and
Joachim R. Sommer Chicken Cardiac Muscle . . . . . . . . . 595
G. Pelletier and
R. Puviani Detection of Glycoproteins and
Autoradiographic Localization of
[$^3$H]Fucose in the Thyroidectomy Cells
of Rat Anterior Pituitary Gland . . . . 600
E. Robert Burns and
Lawrence E. Scheving Isoproterenol-Induced Phase Shifts in
Circadian Rhythm of Mitosis in Murine
Corneal Epithelium . . . . . . . . . . . 605
Lawrence K. Schneider RNA Synthesis in Chromosome Connectives 608
J. D. Lutton The Effect of Phagocytosis and Spreading
on Macrophage Surface Receptors for
Concanavalin A . . . . . . . . . . . . . 611
Richard C. Franson and
Moseley Waite Lysosomal Phospholipases A$_1$ and A$_2$
of Normal and \booktitleBacillus
Calmette Guerin-Induced Alveolar
Macrophages . . . . . . . . . . . . . . 621
Robert W. Rubin and
Philip Filner Adenosine 3 ', 5 '-Cyclic Monophosphate
in Chlamydomonas Reinhardtii . . . . . . 628
Jane Overton Experimental Manipulation of Desmosome
Formation . . . . . . . . . . . . . . . 636
H. Beug and
F. E. Katz and
G. Gerisch Dynamics of Antigenic Membrane Sites
Relating to Cell Aggregation in
\bionameDictyostelium Discoideum . . . . 647
Frederick Grinnell and
Mary Milam and
Paul A. Srere Studies on Cell Adhesion . . . . . . . . 659
J. A. Wright Evidence for Pleiotropic Changes in
Lines of Chinese Hamster Ovary Cells
Resistant to Concanavalin a and
Phytohemagglutinin-P . . . . . . . . . . 666
Michael D. Gershon and
Eladio A. Nunez Subcellular Storage Organelles for
$5$-Hydroxytryptamine in Parafollicular
Cells of the Thyroid Gland . . . . . . . 676
Alex Matter A Morphometric Study on the Nexus of Rat
Cardiac Muscle . . . . . . . . . . . . . 690
Martin A. Gorovsky and
Stanley Hattman and
Gloria Lorick Pleger [$^6$ N]Methyl Adenine in the Nuclear
DNA of a Eucaryote, \bionameTetrahymena
Pyriformis . . . . . . . . . . . . . . . 697
D. Bray Branching Patterns of Individual
Sympathetic Neurons in Culture . . . . . 702
Mary Bartlett Bunge Fine Structure of Nerve Fibers and
Growth Cones of Isolated Sympathetic
Neurons in Culture . . . . . . . . . . . 713
Dorothy Gerber and
Margaret Davies and
Lowell E. Hokin The Effects of Secretagogues on the
Incorporation of [2-$^3$H]Myoinositol
into Lipid in Cytological Fractions in
the Pancreas of the Guinea Pig in Vivo 736
Robert P. Bolender and
Ewald R. Weibel A Morphometric Study of the Removal of
Phenobarbital-Induced Membranes from
Hepatocytes After Cessation of Treatment 746
Robert Nilsson and
Elisabeth Peterson and
Gustav Dallner Permeability of Microsomal Membranes
Isolated from Rat Liver . . . . . . . . 762
H. Rubin and
T. Koide Inhibition of DNA Synthesis in Chick
Embryo Cultures by Deprivation of Either
Serum Or Zinc . . . . . . . . . . . . . 777
P. M. Quinton and
C. W. Philpott A Role for Anionic Sites in Epithelial
Architecture . . . . . . . . . . . . . . 787
Dorothy R. Pitelka and
Susan T. Hamamoto and
Joan G. Duafala and
Michael K. Nemanic Cell Contacts in the Mouse Mammary Gland 797
Brian Storrie and
Giuseppe Attardi Expression of the Mitochondrial Genome
in HeLa Cells . . . . . . . . . . . . . 819
Brian Storrie and
Giuseppe Attardi Mode of Mitochondrial Formation in HeLa
Cells . . . . . . . . . . . . . . . . . 833
Melvyn Weinstock and
C. P. Leblond Radioautographic Visualization of the
Deposition of a Phosphoprotein at the
Mineralization Front in the Dentin of
the Rat Incisor . . . . . . . . . . . . 838
E. Knight Interferon: Effect on the Saturation
Density to Which Mouse Cells Will Grow
in Vitro . . . . . . . . . . . . . . . . 846
James N. Pratley and
Nancy K. McQuillen The Role of Microfilaments in Frog Skin
Ion Transport . . . . . . . . . . . . . 850
Fred R. Butcher and
James F. Perdue Cytochalasin B . . . . . . . . . . . . . 857
Lee-Nien L. Chan and
V. M. Ingram Culture of Erythropoietic Cells from
Chick Blastoderms . . . . . . . . . . . 861
M. S. Forbes and
N. Sperelakis A Labyrinthine Structure Formed from a
Transverse Tubule of Mouse Ventricular
Myocardium . . . . . . . . . . . . . . . 865
Margaret K. Clark and
Paul A. Dahm Phenobarbital-Induced, Membrane-Like
Scrolls in the Oenocytes of
\bionameMusca Domestica Linnaeus . . . . 870
Walter J. Humphreys and
Tomasz J. Wodzicki and
Jerome J. Paulin Fractographic Studies of
Plastic-Embedded Cells by Scanning
Electron Microscopy . . . . . . . . . . 876
Owen Black and
Paul D. Webster Protein Synthesis in Pancreas of Fasted
Pigeons . . . . . . . . . . . . . . . . 1
N. M. Blackett and
D. M. Parry A New Method for Analyzing Electron
Microscope Autoradiographs Using
Hypothetical Grain Distributions . . . . 9
D. M. Parry and
N. M. Blackett Electron Microscope Autoradiography of
Erythroid Cells Using Radioactive Iron 16
Michael Edidin and
Douglas Fambrough Fluidity of the Surface of Cultured
Muscle Fibers . . . . . . . . . . . . . 27
Alexander L. Kisch and
Robert O. Kelley and
Harry Crissman and
Linda Paxton Dimethyl Sulfoxide-Induced Reversion of
Several Features of Polyoma Transformed
Baby Hamster Kidney Cells (Bhk-21) . . . 38
Camillo Peracchia Low Resistance Junctions in Crayfish . . 54
Camillo Peracchia Low Resistance Junctions in Crayfish . . 66
M. M. Magalhães and
Antonio Coimbra Electron Microscope Autoradiographic
Detection of Sites of Protein Synthesis
in the Rabbit Retina M\''ULler Cells . . 77
Saul Teichberg and
Eric Holtzman Axonal Agranular Reticulum and Synaptic
Vesicles in Cultured Embryonic Chick
Sympathetic Neurons . . . . . . . . . . 88
J. V. Anastasia and
R. L. McCarl Effects of Cortisol on Cultured Rat
Heart Cells . . . . . . . . . . . . . . 109
Susan Y. Schmidt and
Richard N. Lolley Cyclic-Nucleotide Phosphodiesterase . . 117
C. Brailovsky and
M. Trudel and
R. Lallier and
V. N. Nigam Growth of Normal and Transformed Rat
Embryo Fibroblasts . . . . . . . . . . . 124
R. E. Stephens A Thermodynamic Analysis of Mitotic
Spindle Equilibrium at Active Metaphase 133
J. G. Williams and
I. A. MacPherson The Differential Effect of Actinomycin D
in Normal and Virus-Transformed Cells 148
J. J. Geuze and
C. Poort Cell Membrane Resorption in the Rat
Exocrine Pancreas Cell After in Vivo
Stimulation of the Secretion, As Studied
by in Vitro Incubation with
Extracellular Space Markers . . . . . . 159
Richard W. Young The Role of the Golgi Complex in Sulfate
Metabolism . . . . . . . . . . . . . . . 175
Elizabeth D. Hay and
James W. Dodson Secretion of Collagen by Corneal
Epithelium . . . . . . . . . . . . . . . 190
Bunsuke Osogoe and
R. W. Tyler and
N. B. Everett The Patterns of Labeling of
Germinal-Center Cells with Tritiated
Deoxycytidine . . . . . . . . . . . . . 215
Kenji Tanaka Intranuclear Microtubule Organizing
Center in Early Prophase Nuclei of the
Plasmodium of the Slime Mold,
\bionamePhysarum Polycephalum . . . . . 220
Kenneth G. Orloff and
Richard L. McCarl The Effects of Metabolic Inhibitors on
Cultured Rat Heart Cells . . . . . . . . 225
Gary W. Grimes Morphological Discontinuity of
Kinetosomes During the Life Cycle of
Oxytricha Fallax . . . . . . . . . . . . 229
Ephraim Yavin and
John H. Menkes The Culture of Dissociated Cells from
Rat Cerebral Cortex . . . . . . . . . . 232
John L. Skosey and
Donald Chow and
Evelyn Damgaard and
Leif B. Sorensen Effect of Cytochalasin B on Response of
Human Polymorphonuclear Leukocytes to
Zymosan . . . . . . . . . . . . . . . . 237
Arne Andersson and
Birger Petersson and
Jan Westman and
John Edwards and
Gudmar Lundqvist and
Claes Hellerström Tissue Culture of A$_2$ Cell-Rich
Pancreatic Islets Isolated from Guinea
Pigs . . . . . . . . . . . . . . . . . . 241
Istvan Hüttner and
Michel Boutet and
Robert H. More Gap Junctions in Arterial Endothelium 247
David Lagunoff Membrane Fusion During Mast Cell
Secretion . . . . . . . . . . . . . . . 252
R. W. D. Rowe The Ultrastructure of Z Disks from
White, Intermediate, and Red Fibers of
Mammalian Striated Muscles . . . . . . . 261
T. Ootaki and
J. J. Wolken Octahedral Crystals in Phycomyces. II 278
Martha E. Fedorko and
Nicholas L. Cross and
James G. Hirsch Appearance and Distribution of Ferritin
in Mouse Peritoneal Macrophages in Vitro
After Uptake of Heterologous
Erythrocytes . . . . . . . . . . . . . . 289
Jacquelyn C. Pendland and
H. C. Aldrich Ultrastructural Organization of
Chloroplast Thylakoids of the Green Alga
``Oocystis Marssonii'' . . . . . . . . . 306
J. E. Heuser and
T. S. Reese Evidence for Recycling of Synaptic
Vesicle Membrane During Transmitter
Release at the Frog Neuromuscular
Junction . . . . . . . . . . . . . . . . 315
Virginia H. Black and
Bruce I. Bogart Peroxisomes in Inner Adrenocortical
Cells of Fetal and Adult Guinea Pigs . . 345
J. B. Rattner and
Stephanie G. Phillips Independence of Centriole Formation and
DNA Synthesis . . . . . . . . . . . . . 359
Garth L. Nicolson Anionic Sites of Human Erythrocyte
Membranes . . . . . . . . . . . . . . . 373
M. A. Wainberg and
C. Howe and
G. C. Godman Enhancement of Sendai Virus-Mediated
Cell Fusion by Cupric Ions . . . . . . . 388
D. B. Thomas and
Gay Medley and
C. A. Lingwood Growth Inhibition of Murine Tumor Cells,
in Vitro, by Puromycin,
[$^6$N]O$^{2'}$-Dibutyryl
3',5'-Adenosine Monophosphate, or
Adenosine . . . . . . . . . . . . . . . 397
Jean R. Wrathall and
Constance Oliver and
Selma Silagi and
Edward Essner Suppression of Pigmentation in Mouse
Melanoma Cells by 5-Bromodeoxyuridine 406
Nicolae Simionescu and
Maia Simionescu and
George E. Palade Permeability of Muscle Capillaries to
Exogenous Myoglobin . . . . . . . . . . 424
Miklós Müller Biochemical Cytology of Trichomonad
Flagellates . . . . . . . . . . . . . . 453
Annemarie Herzfeld and
Micheline Federman and
Olga Greengard Subcellular Morphometric and Biochemical
Analyses of Developing Rat Hepatocytes 475
Rolf Seljelid and
Samuel C. Silverstein and
Zanvil A. Cohn The Effect of Poly-L-Lysine on the
Uptake of Reovirus Double-Stranded RNA
in Macrophages in Vitro . . . . . . . . 484
B. Ceccarelli and
W. P. Hurlbut and
A. Mauro Turnover of Transmitter and Synaptic
Vesicles at the Frog Neuromuscular
Junction . . . . . . . . . . . . . . . . 499
A. R. Stevens and
P. F. Pachler RNA Synthesis and Turnover During
Density-Inhibited Growth and Encystment
of \bionameAcanthamoeba Castellanii . . 525
R. Sederoff and
R. Clynes and
M. Poncz and
S. Hachtel RNA Synthesis by Exogenous RNA
Polymerase on Cytological Preparations
of Chromosomes . . . . . . . . . . . . . 538
K. T. Tokuyasu A Technique for Ultracryotomy of Cell
Suspensions and Tissues . . . . . . . . 551
H. W. Seyberth and
H. Schmidt-Gayk and
K. H. Jakobs and
E. Hackenthal Cyclic Adenosine Monophosphate in
Phagocytizing Granulocytes and Alveolar
Macrophages . . . . . . . . . . . . . . 567
N. Kislev and
C. M. Spolsky and
J. M. Eisenstadt Effect of Chloramphenicol on the
Ultrastructure of Mitochondria in
Sensitive and Resistant Strains of HeLa 571
John N. Telford and
Efraim Racker A Method for Increasing Contrast of
Mitochondrial Inner Membrane Spheres in
Thin Sections of Epon-Araldite Embedded
Tissue . . . . . . . . . . . . . . . . . 580
E. Weidner and
W. Trager Adenosine Triphosphate in the
Extracellular Survival of an
Intracellular Parasite (\bionameNosema
Michaelis, Microsporidia) . . . . . . . 586
Rhea J. C. Levine and
Maynard M. Dewey and
David E. Colflesh Unusual Striated Thick Filaments in
Limulus Skeletal Muscle . . . . . . . . 591
Janet M. Ledingham and
F. O. Simpson Bundles of Intracellular Tubules in
Renal Medullary Interstitial Cells . . . 594
Robert W. Rubin and
William P. Cunningham Partial Purification and
Phosphotungstate Solubilization of Basal
Bodies and Kinetodesmal Fibers from
\bionameTetrahymena Pyriformis . . . . . 601
Francine Benes and
Joan A. Higgins and
Russell J. Barrnett Ultrastructural Localization of
Phospholipid Synthesis in the Rat
Trigeminal Nerve During Myelination . . 613
Thomas L. Rothstein and
J. J. Blum Lysosomal Physiology in
\bionameTetrahymena . . . . . . . . . . 630
Roger B. Howard and
Joseph C. Lee and
Leroy A. Pesch The Fine Structure, Potassium Content,
and Respiratory Activity of Isolated Rat
Liver Parenchymal Cells Prepared by
Improved Enzymatic Techniques . . . . . 642
J. M. Lord and
T. Kagawa and
T. S. Moore and
H. Beevers Endoplasmic Reticulum As the Site of
Lecithin Formation in Castor Bean
Endosperm . . . . . . . . . . . . . . . 659
Pamela Leban Johnston and
Edgar F. Carell Vitamin B$_{12}$ and the Macromolecular
Composition of Euglena . . . . . . . . . 668
Leslie A. Dendy and
Russell L. Deter and
Charles W. Philpott Localization of Na$^+$, K$^+$-ATPase and
other enzymes in teleost pseudobranch 675
Leslie A. Dendy and
Charles W. Philpott and
Russell L. Deter Localization of Na$^+$, K$^+$-ATPase and
other enzymes in teleost pseudobranch 689
B. Huang and
D. R. Pitelka The Contractile Process in the Ciliate,
\bionameStentor Coeruleus . . . . . . . 704
Harvey Bank and
Peter Mazur Visualization of Freezing Damage . . . . 729
Charles K. Jablecki and
John E. Heuser and
Seymour Kaufman Autoradiographic Localization of New RNA
Synthesis in Hypertrophying Skeletal
Muscle . . . . . . . . . . . . . . . . . 743
Stephen H. Howell and
Jay A. Naliboff Conditional Mutants in Chlamydomonas
Reinhardtii Blocked in the Vegetative
Cell Cycle . . . . . . . . . . . . . . . 760
Martin A. Gorovsky and
Gloria Lorick Pleger and
Josephine Bowen Keevert and
Carol A. Johmann Studies on Histone Fraction F2A1 in
Macro- and Micronuclei of
\bionameTetrahymena Pyriformis . . . . . 773
Story C. Landis Ultrastructural Changes in the
Mitochondria of Cerebellar Purkinje
Cells of Nervous Mutant Mice . . . . . . 782
Nam-Hai Chua and
G. Blobel and
P. Siekevitz Isolation of Cytoplasmic and Chloroplast
Ribosomes and Their Dissociation into
Active Subunits from Chlamydomonas
Reinhardtii . . . . . . . . . . . . . . 798
Keith Porter and
David Prescott and
Jearl Frye Changes in Surface Morphology of Chinese
Hamster Ovary Cells During the Cell
Cycle . . . . . . . . . . . . . . . . . 815
R. W. Rubin and
L. P. Everhart The Effect of Cell-To-Cell Contact on
the Surface Morphology of Chinese
Hamster Ovary Cells . . . . . . . . . . 837
Bruce Magun Two Actions of Cyclic AMP on Melanosome
Movement in Frog Skin . . . . . . . . . 845
Wiktor Djaczenko and
Carmen Calenda Visualization of Polysaccharides in the
Cuticle of Oligochaeta by the Tris
$1$-Aziridinyl Phosphine Oxide Method 859
Cheng-Ming Chang and
Robert D. Goldman The Localization of Actin-Like Fibers in
Cultured Neuroblastoma Cells As Revealed
by Heavy Meromyosin Binding . . . . . . 867
Velma C. Chambers The Use of Ruthenium Red in an Electron
Microscope Study of Cytophagocytosis . . 872
John W. Fuseler Repetitive Procurement of Mature Gametes
from Individual Sea Stars and Sea
Urchins . . . . . . . . . . . . . . . . 879
A. Martinez-Palomo and
D. Benitez and
J. Alanis Selective Deposition of Lanthanum in
Mammalian Cardiac Cell Membranes . . . . 1
Wolfgang Klietmann and
Nobuhiro Sato and
Margit M. K. Nass Establishment and Characterization of
Ethidium Bromide Resistance in Simian
Virus $ 40$-Transformed Hamster Cells 11
Robert B. Zurier and
Sylvia Hoffstein and
Gerald Weissmann Mechanisms of Lysosomal Enzyme Release
from Human Leukocytes . . . . . . . . . 27
Frank A. Rawlins A Time-Sequence Autoradiographic Study
of the in Vivo Incorporation of [1,
2-$^3$H]Cholesterol into Peripheral
Nerve Myelin . . . . . . . . . . . . . . 42
David M. Phillips and
Stephanie Gordon Phillips Repopulation of Postmitotic Nucleoli by
Preformed RNA . . . . . . . . . . . . . 54
R. A. Corradino Embryonic Chick Intestine in Organ
Culture . . . . . . . . . . . . . . . . 64
Peter S. Spencer and
Edith R. Peterson and
Ricardo Madrid A. and
Cedric S. Raine Effects of Thallium Salts on Neuronal
Mitochondria in Organotypic
Cord-Ganglia-Muscle Combination Cultures 79
B. R. Brinkley and
Potu N. Rao Nitrous Oxide: Effects on the Mitotic
Apparatus and Chromosome Movement in
HeLa Cells . . . . . . . . . . . . . . . 96
Mark Nameroff and
John A. Trotter and
John M. Keller and
Erlynda Munar Inhibition of Cellular Differentiation
by Phospholipase C . . . . . . . . . . . 107
Carol Johmann and
Ronald A. Eckhardt and
Martin A. Gorovsky The Histones Associated with Condensed
and Extended Chromatin of Mouse Liver 119
John F. Aronson Nuclear Membrane Fusion in Fertilized
Lytechinus Variegatus Eggs . . . . . . . 126
Ken Kadota and
Tomoko Kadota Isolation of Coated Vesicles, Plain
Synaptic Vesicles, and Flocculent
Material from a Crude Synaptosome
Fraction of Guinea Pig Whole Brain . . . 135
Joan Gil and
Oscar K. Reiss Isolation and Characterization of
Lamellar Bodies and Tubular Myelin from
Rat Lung Homogenates . . . . . . . . . . 152
Richard I. Woodruff and
William H. Telfer Polarized Intercellular Bridges in
Ovarian Follicles of the Cecropia Moth 172
Richard Rodewald Intestinal Transport of Antibodies in
the Newborn Rat . . . . . . . . . . . . 189
Portia A. Holt and
John O. Corliss Pattern Variability in Microtubular
Arrays Associated with the Tentacles of
Actinobolina (Ciliatea: Gymnostomatida) 213
B. Allen Flaxman and
Francis V. Cavoto Low-Resistance Junctions in Epithelial
Outgrowths from Normal and Cancerous
Epidermis in Vitro . . . . . . . . . . . 219
Francis V. Cavoto and
B. Allen Flaxman Low-Resistance Pathways Between Mitotic
and Interphase Epidermal Cells in Vitro 223
J. F. David-Ferreira and
K. L. David-Ferreira Gap Junction-Ribosome Association After
Autolysis . . . . . . . . . . . . . . . 226
Lucy T. Comly Microfilaments in Chaos Carolinensis . . 230
W. F. Harris The Geometry of Triplets in Ciliary
Basal Bodies from Primate Oviducts . . . 237
Alexander Sutherland and
Gregory A. Antipa and
Charles F. Ehret Ultracytochemical Observations of
Glycogen Synthesis and Storage During
Infradian Growth of \bionameTetrahymena
Pyriformis . . . . . . . . . . . . . . . 240
Robert H. Gray and
Joan B. Peterson and
Hans Ris The Organization of Yeast Nucleohistone
Fibers . . . . . . . . . . . . . . . . . 244
Dorothy Ford Bainton Sequential Degranulation of the Two
Types of Polymorphonuclear Leukocyte
Granules During Phagocytosis of
Microorganisms . . . . . . . . . . . . . 249
J. F. Perdue The Distribution, Ultrastructure, and
Chemistry of Microfilaments in Cultured
Chick Embryo Fibroblasts . . . . . . . . 265
M. John Chapman and
Leonard R. Miller and
Joseph A. Ontko Localization of the Enzymes of
Ketogenesis in Rat Liver Mitochondria 284
Vijai N. Nigam and
R. Lallier and
C. Brailovsky Ganglioside Patterns and Phenotypic
Characteristics in a Normal Variant and
a Transformed Back Variant of a Simian
Virus $ 40$-Induced Hamster Tumor Cell
Line . . . . . . . . . . . . . . . . . . 307
Robert S. Lake Further Characterization of the
F1-Histone Phosphokinase of
Metaphase-Arrested Animal Cells . . . . 317
Miriam D. Rosenthal and
Joseph B. Warshaw Interaction of Fatty Acid and Glucose
Oxidation by Cultured Heart Cells . . . 332
Kenneth D. Ley and
Marilyn M. Murphy Synchronization of Mitochondrial DNA
Synthesis in Chinese Hamster Cells (Line
Cho) Deprived of Isoleucine . . . . . . 340
Thomas P. Stossel Quantitative Studies of Phagocytosis . . 346
Lajos Pikó and
David G. Chase Role of the Mitochondrial Genome During
Early Development in Mice . . . . . . . 357
A. H. C. Huang and
H. Beevers Localization of Enzymes Within
Microbodies . . . . . . . . . . . . . . 379
Philippa Claude and
Daniel A. Goodenough Fracture Faces of Zonulae Occludentes
from ``Tight'' and ``Leaky'' Epithelia 390
B. L. A. Carter and
H. O. Halvorson Periodic Changes in Rate of Amino Acid
Uptake During Yeast Cell Cycle . . . . . 401
Roger Hand and
Igor Tamm DNA Replication: Direction and Rate of
Chain Growth in Mammalian Cells . . . . 410
Allen Bennett and
Lawrence Bogorad Complementary Chromatic Adaptation in a
Filamentous Blue-Green Alga . . . . . . 419
Gert Kreibich and
Pascale Debey and
David D. Sabatini Selective Release of Content from
Microsomal Vesicles Without Membrane
Disassembly . . . . . . . . . . . . . . 436
Mathew P. Daniels Fine Structural Changes in Neurons and
Nerve Fibers Associated with Colchicine
Inhibition of Nerve Fiber Formation in
Vitro . . . . . . . . . . . . . . . . . 463
A. G. de Bianchi and
W. R. Terra and
F. J. S. Lara Formation of Salivary Secretion in
\bionameRhynchosciara Americana . . . . 470
Bert M. Zuckerman and
Marian Kisiel and
Stanley Himmelhoch Unusual Mitochondrial Cristae in the
Vinegar Eelworm . . . . . . . . . . . . 476
Ezzatollah Keyhani Ribosomal Granules Associated with Outer
Mitochondrial Membrane in Aerobic Yeast
Cells . . . . . . . . . . . . . . . . . 480
William H. Massover Complex Surface Invaginations in Frog
Oocytes . . . . . . . . . . . . . . . . 485
Kenneth D. Noonan and
Arnold J. Levine and
Max M. Burger Cell Cycle-Dependent Changes in the
Surface Membrane As Detected with
[$^3$H] Concanavalin A . . . . . . . . . 491
Daniel K. Podolsky and
Milton M. Weiser Specific Selection of Mitotically Active
Intestinal Cells by Concanavalin
A-Derivatized Fibers . . . . . . . . . . 497
C. Tougard and
B. Kerdelhue and
A. Tixier-Vidal and
M. Jutisz Light and Electron Microscope
Localization of Binding Sites of
Antibodies Against Ovine Luteinizing
Hormone and Its Two Subunits in Rat
Adenohypophysis Using Peroxidase-Labeled
Antibody Technique . . . . . . . . . . . 503
S. Githens and
M. L. Karnovsky Biochemical Changes During Growth and
Encystment of the Cellular Slime Mold
Polysphondylium Pallidum . . . . . . . . 522
S. Githens and
M. L. Karnovsky Phagocytosis by the Cellular Slime Mold
Polysphondylium Pallidum During Growth
and Development . . . . . . . . . . . . 536
Monica J. Trigg and
Salome Gluecksohn-Waelsch Ultrastructural Basis of Biochemical
Effects in a Series of Lethal Alleles in
the Mouse . . . . . . . . . . . . . . . 549
Robert R. Klevecz and
Leon N. Kapp Intermittent DNA Synthesis and Periodic
Expression of Enzyme Activity in the
Cell Cycle of Wi-38 . . . . . . . . . . 564
Maynard M. Dewey and
Rhea J. C. Levine and
David E. Colflesh Structure of Limulus Striated Muscle . . 574
Richard O. Williams and
Lawrence A. Loeb Zinc Requirement for DNA Replication in
Stimulated Human Lymphocytes . . . . . . 594
Frederick Grinnell Concanavalin a Increases the Strength of
Baby Hamster Kidney Cell Attachment to
Substratum . . . . . . . . . . . . . . . 602
Yoshitaka Obara and
Hiroshi Yoshida and
Lee S. Chai and
Herbert Weinfeld and
Avery A. Sandberg Contrast between the environmental pH
dependencies of prophasing and nuclear
membrane formation in
interphase--metaphase cells . . . . . . 608
Keith E. Summers and
I. R. Gibbons Effects of Trypsin Digestion on
Flagellar Structures and Their
Relationship to Motility . . . . . . . . 618
Clara Franzini-Armstrong The Structure of a Simple Z Line . . . . 630
H. Schmitt and
H. Grossfeld and
U. Z. Littauer Mitochondrial Biogenesis During
Differentiation of Artemia Salina Cysts 643
Matthew M. LaVail Kinetics of Rod Outer Segment Renewal in
the Developing Mouse Retina . . . . . . 650
C. F. Millette and
P. G. Spear and
W. E. Gall and
G. M. Edelman Chemical Dissection of Mammalian
Spermatozoa . . . . . . . . . . . . . . 662
William E. Grove and
Terry C. Johnson and
Paul Kelly and
Marvin Luttges Qualitative and Quantitative
Morphological Changes in Subcellular
Fractions from Mouse Cerebral Cortex
During Postnatal Development . . . . . . 676
E. Joan Blanchette-Mackie and
Robert O. Scow Effects of Lipoprotein Lipase on the
Structure of Chylomicrons . . . . . . . 689
Leslie Wilson and
Isaura Meza The Mechanism of Action of Colchicine 709
Paula F. Dehn and
Robin A. Wallace Sequestered and Injected Vitellogenin 721
P. M. Quinton and
Ernest M. Wright and
John McD. Tormey Localization of Sodium Pumps in the
Choroid Plexus Epithelium . . . . . . . 724
William R. Jeffery and
Joseph Frankel and
Lawrence E. de Bault and
Leslie M. Jenkins Analysis of the Schedule of DNA
Replication in Heat-Synchronized
\bionameTetrahymena . . . . . . . . . . 1
Eve P. Reaven and
Stanton G. Axline Subplasmalemmal Microfilaments and
Microtubules in Resting and
Phagocytizing Cultivated Macrophages . . 12
Yukio Ikehara and
Henry C. Pitot Localization of Polysome-Bound Albumin
and Serine Dehydratase in Rat Liver Cell
Fractions . . . . . . . . . . . . . . . 28
J. H. Ehrenreich and
J. J. M. Bergeron and
P. Siekevitz and
G. E. Palade Golgi Fractions Prepared from Rat Liver
Homogenates . . . . . . . . . . . . . . 45
J. J. M. Bergeron and
J. H. Ehrenreich and
P. Siekevitz and
G. E. Palade Golgi Fractions Prepared from Rat Liver
Homogenates . . . . . . . . . . . . . . 73
John G. Bluemink and
Siegfried W. de Laat New Membrane Formation During
Cytokinesis in Normal and Cytochalasin
B-Treated Eggs of \bionameXenopus Laevis 89
Lewis G. Tilney and
Sadashi Hatano and
Harunori Ishikawa and
Mark S. Mooseker The Polymerization of Actin: Its Role in
the Generation of the Acrosomal Process
of Certain Echinoderm Sperm . . . . . . 109
Lidia S. Watrud and
Albert H. Ellingboe Cobalt As a Mitochondrial Density Marker
in a Study of Cytoplasmic Exchange
During Mating of Schizophyllum Commune 127
Kenneth D. Noonan and
Max M. Burger The Relationship of Concanavalin a
Binding to Lectin-Initiated Cell
Agglutination . . . . . . . . . . . . . 134
Jack Rosenbluth Membrane Specialization at an Insect
Myoneural Junction . . . . . . . . . . . 143
T. Simmons and
P. Heywood and
L. Hodge Nuclear Envelope-Associated Resumption
of RNA Synthesis in Late Mitosis of HeLa
Cells . . . . . . . . . . . . . . . . . 150
Michel Rabinovitch and
Mary Jo de Stefano Manganese Stimulates Adhesion and
Spreading of Mouse Sarcoma I Ascites
Cells . . . . . . . . . . . . . . . . . 165
William E. Bowers Lysosomes in Rat Thoracic Duct
Lymphocytes Fractionated by Zonal
Centrifugation . . . . . . . . . . . . . 177
E. Bonucci and
M. Derenzini and
V. Marinozzi The Organic-Inorganic Relationship in
Calcified Mitochondria . . . . . . . . . 185
Samuel James Davidson Protein Absorption by Renal Cells . . . 213
Adriana Hodârnâu and
Silvia Dancea and
Octavian Bârzu Isolation of Highly Purified
Mitochondria from Rat Pancreas . . . . . 222
Gary W. Conrad and
Daniel C. Williams and
F. Rudolf Turner and
Kenneth M. Newrock and
Rudolf A. Raff Microfilaments in the Polar Lobe
Constriction of Fertilized Eggs of
Ilyanassa Obsoleta . . . . . . . . . . . 228
R. G. Sherman Unique Arrangement of Glial Membranes
Between Adjacent Neuromuscular Synapses
in a Spider Muscle . . . . . . . . . . . 234
Martin L. Pall Sexual Induction in Volvox Carteri . . . 238
Bruce Paterson and
Joav Prives Appearance of Acetylcholine Receptor in
Differentiating Cultures of Embryonic
Chick Breast Muscle . . . . . . . . . . 241
Gloria D. Massaro and
Donald Massaro Pulmonary Granular Pneumocytes . . . . . 246
Herbert L. Cooper Degradation of 28S RNA Late in Ribosomal
RNA Maturation in Nongrowing Lymphocytes
and Its Reversal After Growth
Stimulation . . . . . . . . . . . . . . 250
R. A. Waugh and
T. L. Spray and
J. R. Sommer Fenestrations of Sarcoplasmic Reticulum 254
Manley McGill and
T. C. Hsu and
B. R. Brinkley Electron-Dense Structures in
Mitochondria Induced by Short-Term
Ethidium Bromide Treatment . . . . . . . 260
Lewis G. Tilney and
Joseph Bryan and
Doris J. Bush and
Keigi Fujiwara and
Mark S. Mooseker and
Douglas B. Murphy and
Daniel H. Snyder Microtubules: Evidence for 13
Protofilaments . . . . . . . . . . . . . 267
Colin R. Hopkins and
Marilyn G. Farquhar Hormone Secretion by Cells Dissociated
from Rat Anterior Pituitaries . . . . . 276
Donald E. Olins and
Everline B. Wright Glutaraldehyde Fixation of Isolated
Eucaryotic Nuclei . . . . . . . . . . . 304
Sarah P. Gibbs and
Ronald J. Poole Autoradiographic Evidence for Many
Segregating DNA Molecules in the
Chloroplast of Ochromonas Danica . . . . 318
Richard E. Mains and
Paul H. Patterson Primary Cultures of Dissociated
Sympathetic Neurons . . . . . . . . . . 329
Richard E. Mains and
Paul H. Patterson Primary Cultures of Dissociated
Sympathetic Neurons . . . . . . . . . . 346
Richard E. Mains and
Paul H. Patterson Primary Cultures of Dissociated
Sympathetic Neurons . . . . . . . . . . 361
Robert L. Stavis and
Rona Hirschberg Phototaxis in Chlamydomonas Reinhardtii 367
D. L. Taylor and
J. S. Condeelis and
P. L. Moore and
R. D. Allen The Contractile Basis of Amoeboid
Movement . . . . . . . . . . . . . . . . 378
Garth L. Nicolson and
Richard G. Painter Anionic Sites of Human Erythrocyte
Membranes . . . . . . . . . . . . . . . 395
Neil I. Spielholz and
William G. Van der Kloot Localization and Properties of the
Cholinesterase in Crustacean Muscle . . 407
F. C. Charalampous and
N. K. Gonatas and
A. D. Melbourne Isolation and Properties of the Plasma
Membrane of Kb Cells . . . . . . . . . . 421
Nicholas K. Gonatas and
Stratis Avrameas Detection of Plasma Membrane
Carbohydrates with Lectin Peroxidase
Conjugates . . . . . . . . . . . . . . . 436
Judith E. Armstrong and
Russell L. Jones Osmotic regulation of $ \alpha $-amylase
synthesis and polyribosome formation in
aleurone cells of barley . . . . . . . . 444
W. W. Schlaepfer and
R. P. Bunge Effects of Calcium Ion Concentration on
the Degeneration of Amputated Axons in
Tissue Culture . . . . . . . . . . . . . 456
Brian Storrie Antagonism by Dibutyryl Adenosine Cyclic
3',5'-Monophosphate and Testosterone of
Cell Rounding Reactions . . . . . . . . 471
Joyce P. Cox and
Manfred L. Karnovsky The Depression of Phagocytosis by
Exogenous Cyclic Nucleotides,
Prostaglandins, and Theophylline . . . . 480
Paul B. Lazarow and
Christian de Duve The Synthesis and Turnover of Rat Liver
Peroxisomes . . . . . . . . . . . . . . 491
Paul B. Lazarow and
Christian de Duve The Synthesis and Turnover of Rat Liver
Peroxisomes . . . . . . . . . . . . . . 507
P. P. C. Graziadei and
R. S. DeHan Neuronal Regeneration in Frog Olfactory
System . . . . . . . . . . . . . . . . . 525
Linda D. Heding and
David A. Wolff The Cytochemical Examination of
Poliovirus-Induced Cell Damage . . . . . 530
Earl L. Parr and
Jane S. Oei Immobilization of Membrane H-2 Antigens
by Paraformaldehyde Fixation . . . . . . 537
Issei Mabuchi A Myosin-Like Protein in the Cortical
Layer of the Sea Urchin Egg . . . . . . 542
C. W. Abell and
T. M. Monahan The Role of Adenosine 3',5'-Cyclic
Monophosphate in the Regulation of
Mammalian Cell Division . . . . . . . . 549
William B. Neaves Permeability of Sertoli Cell Tight
Junctions to Lanthanum After Ligation of
Ductus Deferens and Ductuli Efferentes 559
C. Richard Zobel Effect of Solution Composition and
Proteolysis on the Conformation of
Axonemal Components . . . . . . . . . . 573
R. Bruce Nicklas Methods for Gentle, Differential Heating
of Part of a Single Living Cell . . . . 595
H. Bruce Bosmann Molecules at the External Nuclear
Surface . . . . . . . . . . . . . . . . 601
P. R. Gabe and
L. E. de Bault Macromolecular Syntheses Related to the
Reproductive Cyst of \bionameTetrahymena
Patula . . . . . . . . . . . . . . . . . 615
Leo Miller Control of 5S RNA Synthesis During Early
Development of Anucleolate and Partial
Nucleolate Mutants of \bionameXenopus
Laevis . . . . . . . . . . . . . . . . . 624
Keith R. Porter and
George J. Todaro and
Virginia Fonte A Scanning Electron Microscope Study of
Surface Features of Viral and
Spontaneous Transformants of Mouse
Balb\slash 3T3 Cells . . . . . . . . . . 633
Samuel Dales and
Konrad C. Hsu and
Ariaki Nagayama The Fine Structure and Immunological
Labeling of the Achromatic Mitotic
Apparatus After Disruption of Cell
Membranes . . . . . . . . . . . . . . . 643
J. Derksen and
H. D. Berendes and
E. Willart Production and Release of a
Locus-Specific Ribonucleoprotein Product
in Polytene Nuclei of \bionameDrosophila
Hydei . . . . . . . . . . . . . . . . . 661
Helmut M. Maul and
Betty Yee Li Hsu and
Thaddeus M. Borun and
Gerd G. Maul Effect of Metabolic Inhibitors on
Nuclear Pore Formation During the HeLa
S$_3$ Cell Cycle . . . . . . . . . . . . 669
Pierluigi Gambetti and
Lucila Autilio-Gambetti and
Brenda Shafer and
LaDorna Pfaff Quantitative Autoradiographic Study of
Labeled RNA in Rabbit Optic Nerve After
Intraocular Injection of [$^3$H]Uridine 677
John T. Knowler and
Harold L. Moses and
Thomas C. Spelsberg Comparison and Characterization of
Nuclear Isolation Procedures As Applied
to Chick Oviduct . . . . . . . . . . . . 685
Ursula Bretz and
Marco Baggiolini Association of the Alkaline Phosphatase
of Rabbit Polymorphonuclear Leukocytes
with the Membrane of the Specific
Granules . . . . . . . . . . . . . . . . 696
John H. Lillie and
Seong S. Han Secretory Protein Synthesis in the
Stimulated Rat Parotid Gland . . . . . . 708
D. Montgomery Bissell and
Lydia E. Hammaker and
Urs A. Meyer Parenchymal Cells from Adult Rat Liver
in Nonproliferating Monolayer Culture 722
Geoffrey S. Chapman and
Albert L. Jones and
Urs A. Meyer and
D. Montgomery Bissell Parenchymal Cells from Adult Rat Liver
in Nonproliferating Monolayer Culture 735
A. Konishi and
W. S. Beacham and
C. C. Hunt Centrioles in Intrafusal Muscle Fibers 749
Beth Burnside and
Chris Kozak and
F. C. Kafatos Tubulin Determination by an Isotope
Dilution-Vinblastine Precipitation
Method . . . . . . . . . . . . . . . . . 755
Alois Knüsel and
Béatrice Lehner and
Clive C. Kuenzle and
Gonzague S. Kistler Isolation of Neuronal Nuclei from Rat
Brain Cortex . . . . . . . . . . . . . . 762
Harry A. Crissman and
John A. Steinkamp Rapid, Simultaneous Measurement of DNA,
Protein, and Cell Volume in Single Cells
from Large Mammalian Cell Populations 766
J. J. M. Bergeron and
W. H. Evans and
I. I. Geschwind Insulin Binding to Rat Liver Golgi
Fractions . . . . . . . . . . . . . . . 771
Yoshiaki Kuriyama and
David J. L. Luck Membrane-Associated Ribosomes in
Mitochondria of Neurospora Crassa . . . 776
Blair Bowers and
Edward D. Korn Cytochemical Identification of
Phosphatase Activity in the Contractile
Vacuole of \bionameAcanthamoeba
Castellanii . . . . . . . . . . . . . . 784
Tsuyoshi Sawai and
Mitsuki Yoneda Wave of Stiffness Propagating Along the
Surface of the Newt Egg During Cleavage 1
Marilyn G. Farquhar and
J. J. M. Bergeron and
George E. Palade Cytochemistry of Golgi Fractions
Prepared from Rat Liver . . . . . . . . 8
Howard J. Allen and
Charles Ault and
Richard J. Winzler and
James F. Danielli Chemical Characterization of the
Isolated Cell Surface of Amoeba . . . . 26
A. L. Kierszenbaum and
Laura L. Tres Nucleolar and Perichromosomal RNA
Synthesis During Meiotic Prophase in the
Mouse Testis . . . . . . . . . . . . . . 39
Joel B. Baseman and
Domenic Paolini and
Harold Amos Stimulation by Insulin of RNA Synthesis
in Chick Fibroblasts . . . . . . . . . . 54
Maurice M. Margulies and
Allan Michaels Ribosomes Bound to Chloroplast Membranes
in Chlamydomonas Reinhardtii . . . . . . 65
William C. Dewel and
Wallis H. Clark A Fine Structural Investigation of
Surface Specializations and the Cortical
Reaction in Eggs of the Cnidarian
Bunodosoma Cavernata . . . . . . . . . . 78
Melvyn Weinstock and
C. P. Leblond Synthesis, Migration, and Release of
Precursor Collagen by Odontoblasts As
Visualized by Radioautography After
[$^3$H]Proline Administration . . . . . 92
Maia Simionescu and
Nicolae Simionescu and
George E. Palade Morphometric Data on the Endothelium of
Blood Capillaries . . . . . . . . . . . 128
Harold P. Erickson Microtubule Surface Lattice and Subunit
Structure and Observations on Reassembly 153
James B. Wade and
Morris J. Karnovsky The Structure of the Zonula Occludens 168
Han van Rijn and
Marinus M. Bevers and
Roeland van Wijk and
Wesley D. Wicks Regulation of Phosphoenolpyruvate
Carboxykinase and Tyrosine Transaminase
in Hepatoma Cell Cultures . . . . . . . 181
John A. McIntyre and
Norton B. Gilula and
Morris J. Karnovsky Cryoprotectant-Induced Redistribution of
Intramembranous Particles in Mouse
Lymphocytes . . . . . . . . . . . . . . 192
I. Brent Heath Mitosis in the Fungus Thraustotheca
Clavata . . . . . . . . . . . . . . . . 204
Jamison Gilder and
James Cronshaw A Biochemical and Cytochemical Study of
Adenosine Triphosphatase Activity in the
Phloem of Nicotian a Tabacum . . . . . . 221
Garth L. Nicolson and
S. J. Singer The Distribution and Asymmetry of
Mammalian Cell Surface Saccharides
Utilizing Ferritin-Conjugated Plant
Agglutinins As Specific Saccharide
Stains . . . . . . . . . . . . . . . . . 236
Jeffrey E. Froehlich and
Martin Rachmeler Inhibition of Cell Growth in the G$_1$
Phase by Adenosine 3',5'-Cyclic
Monophosphate . . . . . . . . . . . . . 249
Gary Bennett and
C. P. Leblond and
Antonio Haddad Migration of Glycoprotein from the Golgi
Apparatus to the Surface of Various Cell
Types As Shown by Radioautography After
Labeled Fucose Injection into Rats . . . 258
Richard D. Sjolund and
Donna D. Smith Freeze-Fracture Studies of
Photosynthetically Deficient
``Supergranal'' Chloroplasts in Tissue
Cultures Containing Virus-Like Particles 285
G. H. Cope and
M. A. Williams Improved Preservation of Parotid Tissue
for Electron Microscopy . . . . . . . . 292
Joachim Stadleb and
Werner W. Franke Characterization of the Colchicine
Binding of Membrane Fractions from Rat
and Mouse Liver . . . . . . . . . . . . 297
Volloer Herzog and
H. Dariush Fahimi The Effect of Glutaraldehyde on Catalase 303
J. T. Stasny and
R. C. Burns and
B. D. Korant and
R. W. F. Hardy Electron Microscopy of the Mo-Fe Protein
from Azotobacter Nitrogenase . . . . . . 311
Dennis M. D. Landis and
T. S. Reese Arrays of Particles in Freeze-Fractured
Astrocytic Membranes . . . . . . . . . . 316
Keith Summers ATP-Induced Sliding of Microtubules in
Bull Sperm Flagella . . . . . . . . . . 321
Marjorie B. Zucker and
Walter Troll and
Sidney Belman The Tumor-Promoter Phorbol Ester
(12-$0$-Tetradecanoyl-Phorbol-$
13$-Acetate), a Potent Aggregating Agent
for Blood Platelets . . . . . . . . . . 325
Larry Sellers and
Daryl Granner Regulation of Tyrosine Aminotransferase
Activity in Two Liver-Derived Permanent
Cell Lines . . . . . . . . . . . . . . . 337
Marijke E. Holtrop and
Lawrence G. Raisz and
Hollis A. Simmons The Effects of Parathyroid Hormone,
Colchicine, and Calcitonin on the
Ultrastructure and the Activity of
Osteoclasts in Organ Culture . . . . . . 346
Lawrence R. Gurley and
Ronald A. Walters and
Robert A. Tobey Cell Cycle-Specific Changes in Histone
Phosphorylation Associated with Cell
Proliferation and Chromosome
Condensation . . . . . . . . . . . . . . 356
Joseph J. Pysh and
Ronald G. Wiley Synaptic Vesicle Depletion and Recovery
in Cat Sympathetic Ganglia Electrically
Stimulated in Vivo . . . . . . . . . . . 365
Yusuf Kapanci and
André Assimacopoulos and
Claude Irle and
André Zwahlen and
Giulio Gabbiani ''Contractile Interstitial Cells'' in
Pulmonary Alveolar Septa: a Possible
Regulator of Ventilation\slash Perfusion
Ratio? . . . . . . . . . . . . . . . . . 375
Richard G. W. Anderson Isolation of Ciliated Or Unciliated
Basal Bodies from the Rabbit Oviduct . . 393
Samuel B. Horowitz and
Leonard C. Moore The Nuclear Permeability, Intracellular
Distribution, and Diffusion of Inulin in
the Amphibian Oocyte . . . . . . . . . . 405
G. P. M. Moore and
Sue Lintern-Moore and
Hannah Peters and
M. Faber RNA Synthesis in the Mouse Oocyte . . . 416
Richard Rodewald and
Morris J. Karnovsky Porous Substructure of the Glomerular
Slit Diaphragm in the Rat and Mouse . . 423
Leighton P. Everhart and
Robert W. Rubin Cyclic Changes in the Cell Surface . . . 434
Leighton P. Everhart and
Robert W. Rubin Cyclic Changes in the Cell Surface . . . 442
Thomas M. O'Connor and
Charles R. Wyttenbach Cell Death in the Embryonic Chick Spinal
Cord . . . . . . . . . . . . . . . . . . 448
David H. DeHeer and
Merle S. Olson and
R. Neal Pinckard Characterization of Rat Liver
Subcellular Membranes . . . . . . . . . 460
Harry L. Malech and
Thomas L. Lentz Microfilaments in Epidermal Cancer Cells 473
Richard N. Trelease and
Wayne M. Becker and
John J. Burke Cytochemical Localization of Malate
Synthase in Glyoxysomes . . . . . . . . 483
Jason Wolfe and
Lewis Rodriguez Inhibition of Nuclear Reconstruction by
Dithiothreitol . . . . . . . . . . . . . 497
G. Giménez-Martín and
C. de la Torre and
M. E. Fernández-Gómez and
A. González-Fernández Experimental Analysis of Nucleolar
Reorganization . . . . . . . . . . . . . 502
M. Johan Broekman and
Nelson P. Westmoreland and
Phin Cohen An Improved Method for Isolating Alpha
Granules and Mitochondria from Human
Platelets . . . . . . . . . . . . . . . 507
Fred R. Butcher and
Rose H. Goldman Effect of cytochalasin B and colchicine
on $ \alpha $-amylase release from rat
parotid tissue slices . . . . . . . . . 519
Phillip N. Dean and
James H. Jett Mathematical Analysis of DNA
Distributions Derived from Flow
Microfluorometry . . . . . . . . . . . . 523
Siegfried W. de Laat and
John G. Bluemink New Membrane Formation During
Cytokinesis in Normal and Cytochalasin
B-Treated Eggs of \bionameXenopus Laevis 529
John R. Feagler and
Thomas W. Tillack and
David D. Chaplin and
Philip W. Majerus The Effects of Thrombin on
Phytohemagglutinin Receptor Sites in
Human Platelets . . . . . . . . . . . . 541
Christine Kent and
M. A. Williams The Nature of
Hypothalamo-Neurohypophyseal
Neurosecretion in the Rat . . . . . . . 554
Phyllis R. Strauss Effects of Serum on Membrane Transport 571
J. S. Frank and
G. A. Langer The Myocardial Interstitium: Its
Structure and Its Role in Ionic Exchange 586
M. S. Forbes and
N. Sperelakis Spheroidal Bodies in the Junctional
Sarcoplasmic Reticulum of Lizard
Myocardial Cells . . . . . . . . . . . . 602
Gert Kreibich and
Ann L. Hubbard and
David D. Sabatini On the Spatial Arrangement of Proteins
in Microsomal Membranes from Rat Liver 616
Jean-Jacques Curgy and
Gérard Ledoigt and
Barbara J. Stevens and
Jean André Mitochondrial and Cytoplasmic Ribosomes
from \bionameTetrahymena Pyriformis . . 628
Joris J. Deman and
Erik A. Bruyneel and
Marc M. Mareel A Study on the Mechanism of
Intercellular Adhesion . . . . . . . . . 641
Akitsugu Saito and
Murray Smigel and
Sidney Fleischer Membrane Junctions in the Intermembrane
Space of Mitochondria from Mammalian
Tissues . . . . . . . . . . . . . . . . 653
James E. Vaughn and
Charles K. Henrikson and
Judith A. Grieshaber A Quantitative Study of Synapses on
Motor Neuron Dendritic Growth Cones in
Developing Mouse Spinal Cord . . . . . . 664
Michael A. Gimbrone and
Ramzi S. Cotran and
Judah Folkman Human Vascular Endothelial Cells in
Culture . . . . . . . . . . . . . . . . 673
C. R. Scheid and
I. A. Macchi Monolayer Cultures Derived from Neonatal
Hamster Pancreas . . . . . . . . . . . . 685
F. C. Steward and
H. W. Israel and
M. M. Salpeter The Labeling of Cultured Cells of
\bionameAcer with [$^{14}$C]Proline and
Its Significance . . . . . . . . . . . . 695
Hans Ris and
Donna F. Kubai An Unusual Mitotic Mechanism in the
Parasitic Protozoan Syndinium Sp . . . . 702
Peter M. Leuenberger and
Alex B. Novikoff Localization of Transport Adenosine
Triphosphatase in Rat Cornea . . . . . . 721
Brenda R. Eisenberg and
Aileen M. Kuda and
James B. Peter Stereological Analysis of Mammalian
Skeletal Muscle . . . . . . . . . . . . 732
Jonas B. Galper Mitochondrial Protein Synthesis in HeLa
Cells . . . . . . . . . . . . . . . . . 755
Douglas M. Gersten and
Thomas W. Kimmerer and
H. Bruce Bosmann The Lysosome Periphery: Biochemical and
Electrokinetic Properties of the
Tritosome Surface . . . . . . . . . . . 764
James H. Martin and
Freida L. Carson and
George J. Race Calcium-Containing Platelet Granules . . 775
Robert M. Singer and
William H. Fishman Characterization of Two HeLa Sublines:
Tcrc-1 Produces Regan Isoenzyme and
Tcrc-2, Non-Regan Isoenzyme . . . . . . 777
C. A. Sprague and
H. Hoehn and
G. M. Martin Ploidy of Living Clones of Human Somatic
Cells Determined by Mensuration at
Metaphase . . . . . . . . . . . . . . . 781
James R. LaFountain Microfilaments in Spermatocytes of
Nephrotoma Suturalis . . . . . . . . . . 784
James K. Koehler and
William D. Perkins Fine Structure Observations on the
Distribution of Antigenic Sites on
Guinea Pig Spermatozoa . . . . . . . . . 789
Harold C. Slavkin and
Gary N. Trump and
Virginia Mansour and
Pamela Matosian and
William G. Mino Localization of H-2 Histocompatibility
Alloantigens on Mouse Embryonic Tooth
Epithelial and Mesenchymal Cell Surfaces 795
J. Meldolesi Dynamics of Cytoplasmic Membranes in
Guinea Pig Pancreatic Acinar Cells . . . 1
Katsuro Koike and
David R. Wolstenholme Evidence for Discontinuous Replication
of Circular Mitochondrial DNA Molecules
from Novikoff Rat Ascites Hepatoma Cells 14
Allen W. Schuetz and
Robin A. Wallace and
James N. Dumont Steroid Inhibition of Protein
Incorporation by Isolated Amphibian
Oocytes . . . . . . . . . . . . . . . . 26
Saul Kit and
Wai-Choi Leung Genetic Control of Mitochondrial
Thymidine Kinase in Human-Mouse and
Monkey-Mouse Somatic Cell Hybrids . . . 35
Nathan A. Berger and
Sister Ann Marie Skinner Characterization of Lymphocyte
Transformation Induced by Zinc Ions . . 45
Paul C. Letourneau and
Norman K. Wessells Migratory Cell Locomotion Versus Nerve
Axon Elongation . . . . . . . . . . . . 56
Thomas E. Ukena and
Joan Z. Borysenko and
Morris J. Karnovsky and
Richard D. Berlin Effects of Colchicine, Cytochalasin B,
and $2$-Deoxyglucose on the
Topographical Organization of
Surface-Bound Concanavalin a in Normal
and Transformed Fibroblasts . . . . . . 70
J. Vergara and
F. Zambrano and
J. D. Robertson and
H. Elrod Isolation and Characterization of
Luminal Membranes from Urinary Bladder 83
R. Blair Evans and
Vera Morhenn and
Albert L. Jones and
Gordon M. Tomkins Concomitant Effects of Insulin on
Surface Membrane Conformation and
Polysome Profiles of Serum-Starved
Balb/c 3T3 Fibroblasts . . . . . . . . . 95
Camillo Peracchia Excitable Membrane Ultrastructure . . . 107
M. J. Connock and
P. R. Kirk and
A. P. Sturdee A Zonal Rotor Method for the Preparation
of Microperoxisomes from Epithelial
Cells of Guinea Pig Small Intestine . . 123
Martin A. Gorovsky and
Josephine Bowen Keevert and
Gloria Lorick Pleger Histone F1 of \bionameTetrahymena
Macronuclei . . . . . . . . . . . . . . 134
D. E. Hillman and
R. Llins Calcium-Containing Electron-Dense
Structures in the Axons of the Squid
Giant Synapse . . . . . . . . . . . . . 146
J. L. Oschman and
T. A. Hall and
P. D. Peters and
B. J. Wall Association of Calcium with Membranes of
Squid Giant Axon . . . . . . . . . . . . 156
J. R. McIntosh Bridges Between Microtubules . . . . . . 166
Henri Beaufay and
Alain Amar-Costesec and
Ernest Feytmans and
Denise Thin\`es-Sempoux and
Maurice Wibo and
Mariette Robbi and
Jacques Berthet Analytical Study of Microsomes and
Isolated Subcellular Membranes from Rat
Liver . . . . . . . . . . . . . . . . . 188
Alain Amar-Costesec and
Henri Beaufay and
Maurice Wibo and
Denise Thin\`es-Sempoux and
Ernest Feytmans and
Mariette Robbi and
Jacques Berthet Analytical Study of Microsomes and
Isolated Subcellular Membranes from Rat
Liver . . . . . . . . . . . . . . . . . 201
Henri Beaufay and
Alain Amar-Costesec and
Denise Thin\`es-Sempoux and
Maurice Wibo and
Mariette Robbi and
Jacques Berthet Analytical Study of Microsomes and
Isolated Subcellular Membranes from Rat
Liver . . . . . . . . . . . . . . . . . 213
L. W. Roti Roti and
A. R. Stevens Effect of $5$-Bromodeoxyuridine on
Growth, Encystment, and Excystment of
\bionameAcanthamoeba Castellanii . . . . 233
José Remacle and
Stanley Fowler and
Henri Beaufay and
Jacques Berthet Ultrastructural localization of
cytochrome B$_5$ on rat liver microsomes
by means of hybrid antibodies labeled
with ferritin . . . . . . . . . . . . . 237
Nehama Zakai and
Abraham Loyter and
Richard G. Kulka Fusion of Erythrocytes and Other Cells
with Retention of Erythrocyte Cytoplasm 241
Lorraine F. Meisner and
Thomas W. Chuprevich and
Stanley L. Inhorn and
Collin B. Johnson Dye-Nucleoprotein Interactions in Giemsa
Banding . . . . . . . . . . . . . . . . 248
Guy A. Thompson and
Lonnie C. Baugh and
Laurie F. Walker Nonlethal Deciliation of
\bionameTetrahymena by a Local
Anesthetic and Its Utility As a Tool for
Studying Cilia Regeneration . . . . . . 253
G. H. Weber and
U. Heine and
M. Cottler-Fox and
G. Beaudreau Direct Visualization of Labeled
Nucleotides in DNA Using Electron
Microscopy and Autoradiography . . . . . 257
Eric Schabtach and
Terry A. Parkening A Method for Sequential High Resolution
Light and Electron Microscopy of
Selected Areas of the Same Material . . 261
Robert P. Bolender Stereological Analysis of the Guinea Pig
Pancreas . . . . . . . . . . . . . . . . 269
Michael L. Higgins and
Lolita Daneo-Moore Factors Influencing the Frequency of
Mesosomes Observed in Fixed and Unfixed
Cells of Streptococcus Faecalis . . . . 288
Chung-Ho Chen and
John W. Greenawalt and
Albert L. Lehninger Biochemical and Ultrastructural Aspects
of Ca$^{2+}$ Transport by Mitochondria
of the Hepatopancreas of the Blue Crab
\bionameCallinectes Sapidus . . . . . . 301
Gerald L. Becker and
Chung-Ho Chen and
John W. Greenawalt and
Albert L. Lehninger Calcium Phosphate Granules in the
Hepatopancreas of the Blue Crab
Callinectes Sapidus . . . . . . . . . . 316
Carol Bibb and
Richard W. Young Renewal of Fatty Acids in the Membranes
of Visual Cell Outer Segments . . . . . 327
Jarnardan K. Reddy and
Daniel L. Azarnoff and
Donald J. Svoboda and
Jada D. Prasad Nafenopin-Induced Hepatic Microbody
(Peroxisome) Proliferation and Catalase
Synthesis in Rats and Mice . . . . . . . 344
Clifford A. Lingwood and
D. Brian Thomas Rapid Changes in Nucleoside Transport
Induced by Growth Inhibitors . . . . . . 359
D. A. Newsome and
R. T. Fletcher and
W. G. Robison and
K. R. Kenyon and
G. J. Chader Effects of Cyclic AMP and Sephadex
Fractions of Chick Embryo Extract on
Cloned Retinal Pigmented Epithelium in
Tissue Culture . . . . . . . . . . . . . 369
William B. Upholt and
Piet Borst Accumulation of Replicative
Intermediates of Mitochondrial DNA in
\bionameTetrahymena Pyriformis Grown in
Ethidium Bromide . . . . . . . . . . . . 383
David Schubert and
A. John Harris and
Carrick E. Devine and
Stephen Heinemann Characterization of a Unique Muscle Cell
Line . . . . . . . . . . . . . . . . . . 398
Robert S. Hikida and
Joseph A. Lombardo Regeneration of Pigeon Fast and Slow
Muscle Fiber Types After Partial
Excision and Mincing . . . . . . . . . . 414
Itzhak Binderman and
Dan Duksin and
Arieh Harell and
Ephraim Katzir (Katchalski) and
Leo Sachs Formation of Bone Tissue in Culture from
Isolated Bone Cells . . . . . . . . . . 427
C. Peter Wolk and
Sam M. Austin and
John Bortins and
Aaron Galonsky Autoradiographic Localization Of
$^{13}$N After Fixation Of
$^{13}$N-Labeled Nitrogen Gas by a
Heterocyst-Forming Blue--Green Alga . . 440
Dorothy A. Schlaeger and
Morton S. Fuchs and
Suk-Hee Kang Ecdysone-Mediated Stimulation of Dopa
Decarboxylase Activity and Its
Relationship to Ovarian Development in
Aedes Aegypti . . . . . . . . . . . . . 454
Ursula Bretz and
Marco Baggiolini and
Rolf Hauser and
Christian Hodel Resolution of Three Distinct Populations
of Nerve Endings from Rat Brain
Homogenates by Zonal Isopycnic
Centrifugation . . . . . . . . . . . . . 466
Armand F. Miranda and
Gabriel C. Godman and
Arline D. Deitch and
Stuart W. Tanenbaum Action of Cytochalasin D on Cells of
Established Lines . . . . . . . . . . . 481
Clara Franzini-Armstrong Freeze Fracture of Skeletal Muscle from
the Tarantula Spider . . . . . . . . . . 501
David L. Brown and
G. Benjamin Bouck Microtubule Biogenesis and Cell Shape in
Ochromonas . . . . . . . . . . . . . . . 514
Gordon I. Kaye and
Cecilia M. Fenoglio and
Frank B. Hoefle and
Jorge Fischbarg Studies on the Cornea . . . . . . . . . 537
Walter L. Davis and
David B. P. Goodman and
James H. Martin and
James L. Matthews and
Howard Rasmussen Vasopressin-Induced Changes in the Toad
Urinary Bladder Epithelial Surface . . . 544
J. H. M. Temmink and
H. Spiele Ruthenium Red Staining of Normal and
Transformed Murine Fibroblasts in Vitro 548
C. Walig and
J. M. M. Walboomers and
J. van der Noordaa Ultrastructural Localization of
Concanavalin a Receptors in Somatic Cell
Hybrids Between Normal Mouse Cells and
Simian Virus $ 40$-Transformed Rat Cells 553
Daniel A. Goodenough Bulk Isolation of Mouse Hepatocyte Gap
Junctions . . . . . . . . . . . . . . . 557
Gary W. Grimes and
Henry R. Mahler and
Philip S. Perlman Nuclear Gene Dosage Effects on
Mitochondrial Mass and DNA . . . . . . . 565
Daniel A. Goodenough and
Norton B. Gilula The Splitting of Hepatocyte Gap
Junctions and Zonulae Occludentes with
Hypertonic Disaccharides . . . . . . . . 575
Joan Smith-Sonneborn and
Michael Klass Changes in the DNA Synthesis Pattern of
Paramecium with Increased Clonal Age and
Interfission Time . . . . . . . . . . . 591
Robert S. Decker Lysosomal Packaging in Differentiating
and Degenerating Anuran Lateral Motor
Column Neurons . . . . . . . . . . . . . 599
Frank Slaby and
Carolyn Brown Changes in the Ribosome Content,
Principal Microsomal Protein
Composition, and Secretory Character of
Mammary Epithelial Rough Endoplasmic
Reticulum During Differentiation . . . . 613
Frank Wunderlich and
Werner Batz and
Volker Speth and
Donald F. H. Wallach Reversible, Thermotropic Alteration of
Nuclear Membrane Structure and
Nucleocytoplasmic RNA Transport in
\bionameTetrahymena . . . . . . . . . . 633
Jacques Padawer Identification of Mast Cells in the
Scanning Electron Microscope by Means of
X-Ray Spectrometry . . . . . . . . . . . 641
Richard T. Ambron and
James E. Goldman and
Elizabeth Barnes Thompson and
James H. Schwartz Synthesis of Glycoproteins in a Single
Identified Neuron of \bionameAplysia
Californica . . . . . . . . . . . . . . 649
Richard T. Ambron and
James E. Goldman and
James H. Schwartz Axonal Transport of Newly Synthesized
Glycoproteins in a Single Identified
Neuron of \bionameAplysia Californica 665
Barbara Anne Wolf and
P. W. Robbins Cell Mitotic Cycle Synthesis of Nil
Hamster Glycolipids Including the
Forssman Antigen . . . . . . . . . . . . 676
R. E. Jones and
A. A. Moscona Effects of Cytosine Arabinoside on
Differential Gene Expression in
Embryonic Neural Retina . . . . . . . . 688
J. Metuzals and
W. E. Mushynski Electron Microscope and Experimental
Investigations of the Neurofilamentous
Network in Deiters' Neurons . . . . . . 701
A. P. Somlyo and
A. V. Somlyo and
C. E. Devine and
P. D. Peters and
T. A. Hall Electron Microscopy and Electron Probe
Analysis of Mitochondrial Cation
Accumulation in Smooth Muscle . . . . . 723
E. R. Phillips and
J. F. Perdue Ultrastructural Distribution of Cell
Surface Antigens in Avian Tumor
Virus-Infected Chick Embryo Fibroblasts 743
Douglas B. Murphy and
Lewis G. Tilney The Role of Microtubules in the Movement
of Pigment Granules in Teleost
Melanophores . . . . . . . . . . . . . . 757
R. T. L. Chan and
I. E. Scheffler Isopycnic Centrifugation of Chromatin in
Renografin Solutions . . . . . . . . . . 780
Gert Kreibich and
David D. Sabatini Selective Release of Content from
Microsomal Vesicles Without Membrane
Disassembly . . . . . . . . . . . . . . 789
David Lagunoff and
Helen Wan Temperature Dependence of Mast Cell
Histamine Secretion . . . . . . . . . . 809
Anders Edström. Effects of Ca$^{2+}$ and Mg$^{2+}$ on
Rapid Axonal Transport of Proteins in
Vitro in Frog Sciatic Nerves . . . . . . 812
Alberto L. Politoff and
Steven Rose and
George D. Pappas The Calcium Binding Sites of Synaptic
Vesicles of the Frog Sartorius
Neuromuscular Junction . . . . . . . . . 818
H. L. Leffert and
S. Sell Alpha$_1$-Fetoprotein Biosynthesis
During the Growth Cycle of
Differentiated Fetal Rat Hepatocytes in
Primary Monolayer Culture . . . . . . . 823
Ole Frederiksen and
Jòrgen Rostgaard Absence of Dilated Lateral Intercellular
Spaces in Fluid-Transporting Frog
Gallbladder Epithelium . . . . . . . . . 830
Theodore L. Steck The Organization of Proteins in the
Human Red Blood Cell Membrane . . . . . 1
Kou M. Hwang and
Linda C. Yang and
Christine K. Carrico and
Rose A. Schulz and
John B. Schenkman and
Alan C. Sartorelli Production of Membrane Whorls in Rat
Liver by Some Inhibitors of Protein
Synthesis . . . . . . . . . . . . . . . 20
Robert S. Decker and
Daniel S. Friend Assembly of Gap Junctions During
Amphibian Neurulation . . . . . . . . . 32
J. R. Smith and
L. Hayflick Variation in the Life-Span of Clones
Derived from Human Diploid Cell Strains 48
V. T. Nachmias Properties of \bionamePhysarum Myosin
Purified by a Potassium Iodide Procedure 54
Marie Kopecká and
H. J. Phaff and
G. H. Fleet Demonstration of a Fibrillar Component
in the Cell Wall of the Yeast
\bionameSaccharomyces Cerevisiae and Its
Chemical Nature . . . . . . . . . . . . 66
L. Boquist and
B. Hellman and
Å. Lernmark and
I.-B. Täljedal Influence of the Mutation ``Diabetes''
on Insulin Release and Islet Morphology
in Mice of Different Genetic Backgrounds 77
O. Stein and
L. Sanger and
Y. Stein Colchicine-Induced Inhibition of
Lipoprotein and Protein Secretion into
the Serum and Lack of Interference with
Secretion of Biliary Phospholipids and
Cholesterol by Rat Liver in Vivo . . . . 90
Yoshitaka Obara and
Lee S. Chai and
Herbert Weinfeld and
Avery A. Sandberg Prophasing of Interphase Nuclei and
Induction of Nuclear Envelopes Around
Metaphase Chromosomes in HeLa and
Chinese Hamster Homo- and Heterokaryons 104
D. J. Kemp and
P. Y. Dyer and
G. E. Rogers Keratin Synthesis During Development of
the Embryonic Chick Feather . . . . . . 114
Wu-Nan Wen and
Pedro E. León and
Donald R. Hague Multiple Gene Sites for 5S and 18 + 28S
RNA on Chromosomes of Glyptotendipes
Barbipes (Staeger) . . . . . . . . . . . 132
Joanne S. Ingwall and
Cynthia D. Weiner and
Manuel F. Morales and
Elaine Davis and
Frank E. Stockdale Specificity of Creatine in the Control
of Muscle Protein Synthesis . . . . . . 145
G. L. Kimmel and
F. G. Péron and
A. Haksar and
E. Bedigian and
W. F. Robidoux and
M. T. Lin Ultrastructure, Steroidogenic Potential,
and Energy Metabolism of the Snell
Adrenocortical Carcinoma 494 . . . . . . 152
Ilona Staprans and
Ellen Roter Dirksen Microtubule Protein During Ciliogenesis
in the Mouse Oviduct . . . . . . . . . . 164
Shinya Inoué and
Gary G. Borisy and
Daniel P. Kiehart Growth and Lability of
\bionameChaetopterus Oocyte Mitotic
Spindles Isolated in the Presence of
Porcine Brain Tubulin . . . . . . . . . 175
Georges Pelletier Autoradiographic Studies of Synthesis
and Intracellular Migration of
Glycoproteins in the Rat Anterior
Pituitary Gland . . . . . . . . . . . . 185
Albert DiPasquale and
Paul B. Bell The Upper Cell Surface: Its Inability to
Support Active Cell Movement in Culture 198
A. G. Gambarini and
F. J. S. Lara Under-Replication of Ribosomal Cistrons
in Polytene Chromosomes of Rhynchosciara 215
T. L. Spray and
R. A. Waugh and
J. R. Sommer Peripheral Couplings in Adult Vertebrate
Skeletal Muscle . . . . . . . . . . . . 223
J. J. McCormick Physical Separation of Nuclei from Two
Independent Plasmodia of
\bionamePhysarum Polycephalum After
Fusion . . . . . . . . . . . . . . . . . 227
Daniel W. McKeel and
Leonard Jarett The Enrichment of Adenylate Cyclase in
the Plasma Membrane and Golgi
Subcellular Fractions of Porcine
Adenohypophysis . . . . . . . . . . . . 231
C. W. Cotman and
D. Taylor Localization and Characterization of
Concanavalin a Receptors in the Synaptic
Cleft . . . . . . . . . . . . . . . . . 236
John N. Howell Intracellular Binding of Ruthenium Red
in Frog Skeletal Muscle . . . . . . . . 242
Brian Storrie Effect of Dibutyryl Adenosine Cyclic
3',5'-Monophosphate and Testololactone
on Concanavalin a Binding and Cell
Killing . . . . . . . . . . . . . . . . 247
Lily Yeh Jan and
Jean-Paul Revel Ultrastructural Localization of
Rhodopsin in the Vertebrate Retina . . . 257
Peggy R. Hudson and
J. Robert Waaland Ultrastructure of Mitosis and
Cytokinesis in the Multinucleate Green
Alga Acrosiphonia . . . . . . . . . . . 274
Susannah T. Rohrlich Fine Structural Demonstration of Ordered
Arrays of Cytoplasmic Filaments in
Vertebrate Iridophores . . . . . . . . . 295
M. P. Siegers and
J. C. Schaer and
H. Hirsiger and
R. Schindler Determination of Rates of DNA Synthesis
in Cultured Mammalian Cell Populations 305
Anne E. Lykkesfeldt and
H. A. Andersen The Effect of $5$-Bromodeoxyuridine on
DNA Replication and Cell Division in
\bionameTetrahymena Pyriformis . . . . . 316
M. E. J. Holwill and
Patricia D. Peters Dynamics of the Hispid Flagellum of
Ochromonas Danica . . . . . . . . . . . 322
Marilynn E. Etzler and
Margaret L. Branstrator Differential Localization of Cell
Surface and Secretory Components in Rat
Intestinal Epithelium by Use of Lectins 329
James B. Wade and
Morris J. Karnovsky Fracture Faces of Osmotically Disrupted
Zonulae Occludentes . . . . . . . . . . 344
Graeme B. Ryan and
Joan Z. Borysenko and
Morris J. Karnovsky Factors Affecting the Redistribution of
Surface-Bound Concanavalin a on Human
Polymorphonuclear Leukocytes . . . . . . 351
Gary R. Gunther and
John L. Wang and
Gerald M. Edelman The Kinetics of Cellular Commitment
During Stimulation of Lymphocytes by
Lectins . . . . . . . . . . . . . . . . 366
Carol Bibb and
Richard W. Young Renewal of Glycerol in the Visual Cells
and Pigment Epithelium of the Frog
Retina . . . . . . . . . . . . . . . . . 378
H. Paul Ehrlich and
Russell Ross and
Paul Bornstein Effects of Antimicrotubular Agents on
the Secretion of Collagen . . . . . . . 390
Armand F. Miranda and
Gabriel C. Godman and
Stuart W. Tanenbaum Action of Cytochalasin D on Cells of
Established Lines . . . . . . . . . . . 406
J. B. Tucker Microtubule Arms and Cytoplasmic
Streaming and Microtubule Bending and
Stretching of Intertubule Links in the
Feeding Tentacle of the Suctorian
Ciliate Tokophrya . . . . . . . . . . . 424
Richard O. Hynes and
Kenneth C. Humphryes Characterization of the External
Proteins of Hamster Fibroblasts . . . . 438
Andrew Churg and
Winston A. Anderson Induction of Endometrial Peroxidase
Synthesis and Secretion by Estrogen and
Estrogen Antagonist . . . . . . . . . . 449
Marvin R. Kalt and
Joseph G. Gall Observations on Early Germ Cell
Development and Premeiotic Ribosomal DNA
Amplification in \bionameXenopus Laevis 460
Carol A. Sattler and
L. Andrew Staehelin Ciliary Membrane Differentiations in
\bionameTetrahymena Pyriformis . . . . . 473
William P. Cunningham and
L. Andrew Staehelin and
Robert W. Rubin and
Ross Wilkins and
Mary Bonneville Effects of Phosphotungstate Negative
Staining on the Morphology of the
Isolated Golgi Apparatus . . . . . . . . 491
L. de Meis and
W. Hasselbach and
R. D. Machado Characterization of Calcium Oxalate and
Calcium Phosphate Deposits in
Sarcoplasmic Reticulum Vesicles . . . . 505
Hiroshi Nogami and
Marshall R. Urist Substrata Prepared from Bone Matrix for
Chondrogenesis in Tissue Culture . . . . 510
M. Kagayama and
W. W. Douglas Electron Microscope Evidence of
Calcium-Induced Exocytosis in Mast Cells
Treated with 48/80 Or the Ionophores
A-23187 and X-537A . . . . . . . . . . . 519
J. B. Rattner and
Michael W. Berns Light and Electron Microscopy of Laser
Microirradiated Chromosomes . . . . . . 526
Blair Bowers and
Edward D. Korn Localization of Lipophosphonoglycan on
Both Sides of \bionameAcanthamoeba
Plasma Membrane . . . . . . . . . . . . 533
Ephraim Yavin and
Ziva Yavin Attachment and Culture of Dissociated
Cells from Rat Embryo Cerebral
Hemispheres on Polylysine-Coated Surface 540
Samuel A. Latt Detection of DNA Synthesis in Interphase
Nuclei by Fluorescence Microscopy . . . 546
Takami Oka and
John W. Perry and
Yale J. Topper Changes in Insulin Responsiveness During
Development of Mammary Epithelium . . . 550
Richard L. Wood A Closely Packed Array of Membrane
Intercalated Particles at the Free
Surface of Hydra . . . . . . . . . . . . 556
Georgirene D. Vladutiu and
Noel R. Rose Intracellular Distribution of a
Primate-Specific Esterase in Cultured
Cells and Tissues . . . . . . . . . . . 560
David R. Burgess and
Robert D. Grey Alterations in Morphology of Developing
Microvilli Elicited by Cytochalasin B 566
M. Borgers and
S. de Nollin The Preservation of Subcellular
Organelles of Candida Albicans with
Conventional Fixatives . . . . . . . . . 574
Massimo Olivotto and
Francesco Paoletti Protein Metabolism in Tumor Cells at
Various Stages of Growth in Vivo . . . . 585
John I. Gallin and
Alan S. Rosenthal The Regulatory Role of Divalent Cations
in Human Granulocyte Chemotaxis . . . . 594
Michael D. Gershon and
Martin Hagopian and
Eladio A. Nunez An Electron Microscope Autoradiographic
Study of the Neuronal and Extraneuronal
Localization of Labeled Amine in the
Heart of the Bat After Administration of
Tritiated Norepinephrine . . . . . . . . 610
John L. Skosey and
Evelyn Damgaard and
Donald Chow and
Leif B. Sorensen Modification of Zymosan-Induced Release
of Lysosomal Enzymes from Human
Polymorphonuclear Leukocytes by
Cytochalasin B . . . . . . . . . . . . . 625
Joan A. Higgins Studies on the Biogenesis of Smooth
Endoplasmic Reticulum Membranes in
Hepatocytes of Phenobarbital-Treated
Rats . . . . . . . . . . . . . . . . . . 635
Stanton G. Axline and
Eve P. Reaven Inhibition of Phagocytosis and Plasma
Membrane Mobility of the Cultivated
Macrophage by Cytochalasin B . . . . . . 647
Robert A. Bloodgood and
Kenneth R. Miller Freeze-Fracture of Microtubules and
Bridges in Motile Axostyles . . . . . . 660
George H. Goetz and
Pamela L. Johnston and
Kathy Dobrosielski-Vergona and
Edgar F. Carell Vitamin B$_{12}$ and the Macromolecular
Composition of Euglena . . . . . . . . . 672
S. Knutton and
A. R. Limbrick and
J. D. Robertson Regular Structures in Membranes . . . . 679
Michael Durphy and
Paul N. Manley and
Errol C. Friedberg A Demonstration of Several
Deoxyribonuclease Activities in
Mammalian Cell Mitochondria . . . . . . 695
Charles T. Roberts and
Eduardo Orias On the Mechanism of Adaptation to
Protein Synthesis Inhibitors by
\bionameTetrahymena . . . . . . . . . . 707
Alain Amar-Costesec and
Maurice Wibo and
Denise Thin\`es-Sempoux and
Henri Beaufay and
Jacques Berthet Analytical Study of Microsomes and
Isolated Subcellular Membranes from Rat
Liver . . . . . . . . . . . . . . . . . 717
Robert Peter Aaronson and
Günter Blobel On the Attachment of the Nuclear Pore
Complex . . . . . . . . . . . . . . . . 746
Jack Rosenbluth Substructure of Amphibian Motor End
Plate . . . . . . . . . . . . . . . . . 755
H. L. Leffert Growth Control of Differentiated Fetal
Rat Hepatocytes in Primary Monolayer
Culture . . . . . . . . . . . . . . . . 767
K. Koch and
H. L. Leffert Growth Control of Differentiated Fetal
Rat Hepatocytes in Primary Monolayer
Culture . . . . . . . . . . . . . . . . 780
H. L. Leffert Growth Control of Differentiated Fetal
Rat Hepatocytes in Primary Monolayer
Culture . . . . . . . . . . . . . . . . 792
Martha E. Fedorko Loss of Iron from Mouse Peritoneal
Macrophages in Vitro After Uptake of
[$^{55}$ Fe]Ferritin and [$^{55}$
Fe]Ferritin Rabbit Antiferritin
Complexes . . . . . . . . . . . . . . . 802
Robert L. Trelstad and
Kimiko Hayashi and
Bryan P. Toole Epithelial Collagens and
Glycosaminoglycans in the Embryonic
Cornea . . . . . . . . . . . . . . . . . 815
George K. Chacko and
David E. Goldman and
Harish C. Malhotra and
Maynard M. Dewey Isolation and Characterization of Plasma
Membrane Fractions from Garfish
Lepisosteus Osseus Olfactory Nerve . . . 831
Thomas L. Rothstein and
J. J. Blum Lysosomal Physiology in
\bionameTetrahymena . . . . . . . . . . 844
W. Kleinow and
W. Neupert and
F. Miller Electron Microscope Study of
Mitochondrial 60S and Cytoplasmic 80S
Ribosomes from Locusta Migratoria . . . 860
A. Carabez and
F. Sandoval A mitochondrial inner membrane
preparation that sediments at 100 $g$ 877
D. Huang Effect of Extracellular Chondroitin
Sulfate on Cultured Chondrocytes . . . . 881
Joseph M. Harb and
D. Eugene Copeland Helical Form Cristae in the Mitochondria
of the Pseudobranch of Cyprinodon
Variegatus Adapted to Conditions of
Constant Light and Darkness . . . . . . 886
Elizabeth D. Hay and
Stephen Meier Glycosaminoglycan Synthesis by Embryonic
Inductors: Neural Tube, Notochord, and
Lens . . . . . . . . . . . . . . . . . . 889
Ellen Roter Dirksen Ciliogenesis in the Mouse Oviduct . . . 899
Warren M. Pulich Resistance to High Oxygen Tension,
Streptonigrin, and Ultraviolet
Irradiation in the Green Alga Chlorella
Sorokiniana Strain Ors . . . . . . . . . 904
M. Kumegawa and
T. Nakamura and
T. Yamada Studies on the Effect of Selective
Membrane Filtration on the
Differentiation of Tissue Cultures . . . 908
David M. Phillips Nuclear Shaping in the Absence of
Microtubules in Scorpion Spermatids . . 911
Beverly H. Bergstrom and
John M. Arnold Nonkinetochore Association of Chromatin
and Microtubules . . . . . . . . . . . . 917
Hava Peretz and
Zivia Toister and
Yehudith Laster and
Abraham Loyter Fusion of Intact Human Erythrocytes and
Erythrocyte Ghosts . . . . . . . . . . . 1
Jean-Claude Antoine and
Stratis Avrameas and
Nicholas K. Gonatas and
Anna Stieber and
Jacqueline O. Gonatas Plasma Membrane and Internalized
Immunoglobulins of Lymph Node Cells
Studied with Conjugates of Antibody Or
Its Fab Fragments with Horseradish
Peroxidase . . . . . . . . . . . . . . . 12
Melvin P. Garber and
Peter L. Steponkus Identification of Chloroplast Coupling
Factor by Freeze-Etching and
Negative-Staining Techniques . . . . . . 24
Fred D. Warner and
Peter Satir The Structural Basis of Ciliary Bend
Formation . . . . . . . . . . . . . . . 35
Robert Narotzky and
William Bondareff Biogenic Amines in Cultured
Neuroblastoma and Astrocytoma Cells . . 64
Lloyd A. Culp Substrate-Attached Glycoproteins
Mediating Adhesion of Normal and
Virus-Transformed Mouse Fibroblasts . . 71
Ronald A. Coss and
Jeremy D. Pickett-Heaps The Effects of Isopropyl N-Phenyl
Carbamate on the Green Alga
\bionameOedogonium Cardiacum . . . . . . 84
William B. Winborn and
Leonard L. Seelig Pattern of Osmium Deposition in the
Parietal Cells of the Stomach . . . . . 99
Dominic K. Yip and
Nelly Auersperg Structural and Functional Heterogeneity
of the Surface of Rat Leukemia Cells . . 109
Robert S. Rew and
Howard J. Saz Enzyme Localization in the Anaerobic
Mitochondria of Ascaris Lumbricoides . . 125
James P. Whitlock and
Haruko Miller and
Harry V. Gelboin Induction of aryl hydrocarbon
(benzo[a]pyrene) hydroxylase and
tyrosine aminotransferase in hepatoma
cells in culture . . . . . . . . . . . . 136
Lloyd Matsumoto and
Harumi Kasamatsu and
Lajos Pikó and
Jerome Vinograd Mitochondrial DNA Replication in Sea
Urchin Oocytes . . . . . . . . . . . . . 146
Elizabeth H. Harris and
John E. Boynton and
Nicholas W. Gillham Chloroplast Ribosome Biogenesis in
Chlamydomonas . . . . . . . . . . . . . 160
Karl H. Pfenninger and
Richard P. Bunge Freeze-Fracturing of Nerve Growth Cones
and Young Fibers . . . . . . . . . . . . 180
Antti Penttila and
Hannu Kalimo and
Benjamin F. Trump Influence of Glutaraldehyde And/Or
Osmium Tetroxide on Cell Volume, Ion
Content, Mechanical Stability, and
Membrane Permeability of Ehrlich Ascites
Tumor Cells . . . . . . . . . . . . . . 197
Philip B. Dunham and
Ira M. Goldstein and
Gerald Weissmann Potassium and Amino Acid Transport in
Human Leukocytes Exposed to Phagocytic
Stimuli . . . . . . . . . . . . . . . . 215
Wojciech Sawicki and
Jan Rowínski and
Jan Abramczuk Image Analysis of Chromatin in Cells of
Preimplantation Mouse Embryos . . . . . 227
David F. Albertini and
Everett Anderson The Appearance and Structure of
Intercellular Connections During the
Ontogeny of the Rabbit Ovarian Follicle
with Particular Reference to Gap
Junctions . . . . . . . . . . . . . . . 234
Ursula Bretz and
Marco Baggiolini Biochemical and Morphological
Characterization of Azurophil and
Specific Granules of Human Neutrophilic
Polymorphonuclear Leukocytes . . . . . . 251
Nina Strömgren Allen Endoplasmic Filaments Generate the
Motive Force for Rotational Streaming in
Nitella . . . . . . . . . . . . . . . . 270
Mark C. Willingham and
Ira Pastan Cyclic AMP Mediates the Concanavalin a
Agglutinability of Mouse Fibroblasts . . 288
Richard A. Miller and
Frank H. Ruddle Enucleated Neuroblastoma Cells Form
Neurites When Treated with Dibutyryl
Cyclic Amp . . . . . . . . . . . . . . . 295
Tsuneyoshi Kuroiwa Studies on Mitochondrial Structure and
Function in \bionamePhysarum
Polycephalum . . . . . . . . . . . . . . 299
Marcia Perlman and
Jules L. Baum and
Gordon I. Kaye Fine Structure and Collagen Synthesis
Activity of Monolayer Cultures of Rabbit
Corneal Endothelium . . . . . . . . . . 306
Liane Reif-Lehrer Effect of washout of inducing steroid on
$ \gamma $-glutamyl transferase activity
in the cultured chick embryo retina . . 312
James A. McKanna Permeability Modulating Membrane Coats 317
B. R. Oakley and
J. D. Dodge Kinetochores Associated with the Nuclear
Envelope in the Mitosis of a
Dinoflagellate . . . . . . . . . . . . . 322
Ronald A. Coss Mitosis in Chlamydomonas Reinhardtii
Basal Bodies and the Mitotic Apparatus 325
H. L. Atwood and
B. Pomeranz Crustacean Motor Neuron Connections
Traced by Backfilling for Electron
Microscopy . . . . . . . . . . . . . . . 329
K. T. Tokuyasu Spoke Heads in Sperm Tail of
\bionameDrosophila Melanogaster . . . . 334
R. A. Waugh and
J. R. Sommer Lamellar Junctional Sarcoplasmic
Reticulum . . . . . . . . . . . . . . . 337
Tom Elsdale and
Jonathan Bard Cellular Interactions in Morphogenesis
of Epithelial Mesenchymal Systems . . . 343
Claude Pricam and
Fabienne Humbert and
Alain Perrelet and
Lelio Orci Gap Junctions in Mesangial and Lacis
Cells . . . . . . . . . . . . . . . . . 349
Sven Johnsen and
Torbjòrn Stokke and
Hans Prydz HeLa Cell Plasma Membranes . . . . . . . 357
S. Ito and
G. C. Schofield Studies on the Depletion and
Accumulation of Microvilli and Changes
in the Tubulovesicular Compartment of
Mouse Parietal Cells in Relation to
Gastric Acid Secretion . . . . . . . . . 364
Paul Tulkens and
Henry Beaufay and
André Trouet Analytical Fractionation of Homogenates
from Cultured Rat Embryo Fibroblasts . . 383
P. R. Harrison and
D. Conkie and
N. Affara and
J. Paul In Situ Localization of Globin Messenger
RNA Formation . . . . . . . . . . . . . 402
D. Conkie and
N. Affara and
P. R. Harrison and
J. Paul and
K. Jones In Situ Localization of Globin Messenger
RNA Formation . . . . . . . . . . . . . 414
David H. Miller and
Ira Seth Mellman and
Derek T. A. Lamport and
Maureen Miller The Chemical Composition of the Cell
Wall of Chlamydomonas Gymnogama and the
Concept of a Plant Cell Wall Protein . . 420
Maurice Wibo and
Brian Poole Protein Degradation in Cultured Cells 430
C. W. Cotman and
G. Banker and
L. Churchill and
D. Taylor Isolation of Postsynaptic Densities from
Rat Brain . . . . . . . . . . . . . . . 441
G. Banker and
L. Churchill and
C. W. Cotman Proteins of the Postsynaptic Density . . 456
Daniel S. Friend and
Irene Rudolf Acrosomal Disruption in Sperm . . . . . 466
John C. Saari The Accessibility of Bovine Rhodopsin in
Photoreceptor Membranes . . . . . . . . 480
Wayne E. Magee and
Charles W. Goff and
Jean Schoknecht and
M. Diane Smith and
K. Cherian The Interaction of Cationic Liposomes
Containing Entrapped Horseradish
Peroxidase with Cells in Culture . . . . 492
Saul Kit and
Wai-Choi Leung and
George Jorgensen and
David Trkula and
Del Rose Dubbs Acquisition of Chick Cytosol Thymidine
Kinase Activity by Thymidine
Kinase-Deficient Mouse Fibroblast Cells
After Fusion with Chick Erythrocytes . . 505
Christine J. Skerrow and
A. Gedeon Matoltsy Isolation of Epidermal Desmosomes . . . 515
Christine J. Skerrow and
A. Gedeon Matoltsy Chemical Characterization of Isolated
Epidermal Desmosomes . . . . . . . . . . 524
Robert E. Hinkley and
Alvin G. Telser The Effects of Halothane on Cultured
Mouse Neuroblastoma Cells . . . . . . . 531
John G. Wood and
Barbara J. McLaughlin and
Robert P. Barber The Visualization of Concanavalin a
Binding Sites in Purkinje Cell Somata
and Dendrites of Rat Cerebellum . . . . 541
Robert H. Warren Microtubular Organization in Elongating
Myogenic Cells . . . . . . . . . . . . . 550
John E. Rash and
Mark H. Ellisman Studies of Excitable Membranes . . . . . 567
Izhak Nir and
Michael O. Hall The Ultrastructure of Lipid-Depleted Rod
Photoreceptor Membranes . . . . . . . . 587
S. S. Jahromi and
H. L. Atwood Three-Dimensional Ultrastructure of the
Crayfish Neuromuscular Apparatus . . . . 599
Lionel F. Jaffe and
Richard Nuccitelli An Ultrasensitive Vibrating Probe for
Measuring Steady Extracellular Currents 614
S. Matsuura and
T. Morimoto and
Y. Tashiro and
T. Higashinakagawa and
M. Muramatsu Ultrastructural and Biochemical Studies
on the Precursor Ribosomal Particles
Isolated from Rat Liver Nucleoli . . . . 629
Daniel S. Friend and
Don W. Fawcett Membrane Differentiations in
Freeze-Fractured Mammalian Sperm . . . . 641
V. Mare\vs and
B. Schultze and
W. Maurer Stability of DNA in Purkinje Cell Nuclei
of the Mouse . . . . . . . . . . . . . . 665
H. Dariush Fahimi Effect of Buffer Storage on Fine
Structure and Catalase Cytochemistry of
Peroxisomes . . . . . . . . . . . . . . 675
Kenjiro Wake Development of Vitamin A-Rich Lipid
Droplets in Multivesicular Bodies of Rat
Liver Stellate Cells . . . . . . . . . . 683
Mathew P. Daniels and
Bernd Hamprecht The Ultrastructure of Neuroblastoma
Glioma Somatic Cell Hybrids . . . . . . 691
Nancy K. Weller Visualization of Concanavalin A-Binding
Sites with Scanning Electron Microscopy 699
Barbara K. Vonderhaar and
Yale J. Topper A Role of the Cell Cycle in
Hormone-Dependent Differentiation . . . 707
Audrey M. Glauert The High Voltage Electron Microscope in
Biology . . . . . . . . . . . . . . . . 717
Yoichi Tamai and
Shigeko Matsukawa Araki and
Kimio Katsuta and
Mei Satake Molecular Composition of the
Submicrosomal Membrane Lipid of Rat
Brain . . . . . . . . . . . . . . . . . 749
David P. Beck and
R. P. Levine Synthesis of Chloroplast Membrane
Polypeptides During Synchronous Growth
of Chlamydomonas Reinhardtii . . . . . . 759
Robert H. F. Peterson and
Judith A. O'Neil and
June L. Biedler Some Biochemical Properties of Chinese
Hamster Cells Sensitive and Resistant to
Actinomycin D . . . . . . . . . . . . . 773
Alan F. Boyne and
Timothy P. Bohan and
Terence H. Williams Effects of Calcium-Containing Fixation
Solutions on Cholinergic Synaptic
Vesicles . . . . . . . . . . . . . . . . 780
Glenda C. Webb and
Stephen Roth Cell Contact Dependence of Surface
Galactosyltransferase Activity As a
Function of the Cell Cycle . . . . . . . 796
Wei-Yeh Wang and
Wenan Lee Wang and
John E. Boynton and
Nicholas W. Gillham Genetic Control of Chlorophyll
Biosynthesis in Chlamydomonas . . . . . 806
Karl W. Lanks and
Jan M. Dorwin and
Bruno Papirmeister Increased Rate of Acetylcholinesterase
Synthesis in Differentiating
Neuroblastoma Cells . . . . . . . . . . 824
Claude Kedinger and
Rene Simard The action of $ \alpha $-amanitin on RNA
synthesis in Chinese hamster ovary cells 831
Jon C. Daniel and
Robert A. Kosher and
James E. Hamos and
James W. Lash Influence of External Potassium on the
Synthesis and Deposition of Matrix
Components by Chondrocytes in Vitro . . 843
Dorothea Zucker-Franklin and
George Grusky Ultrastructural Analysis of
Hematopoietic Colonies Derived from
Human Peripheral Blood . . . . . . . . . 855
Stephen J. O'Brien and
Yoshio Shimada The $ \alpha $-glycerophosphate cycle in
\bionameDrosophila melanogaster . . . . 864
John P. Caulfield and
Marilyn G. Farquhar The Permeability of Glomerular
Capillaries to Graded Dextrans . . . . . 883
Richard D. Allen Food Vacuole Membrane Growth with
Microtubule-Associated Membrane
Transport in Paramecium . . . . . . . . 904
A. L. Kierszenbaum and
Laura L. Tres Transcription Sites in Spread Meiotic
Prophase Chromosomes from Mouse
Spermatocytes . . . . . . . . . . . . . 923
Susan Oleszko and
Evangelos N. Moudrianakis The Visualization of the Photosynthetic
Coupling Factor in Embedded Spinach
Chloroplasts . . . . . . . . . . . . . . 936
Ralph M. Steinman and
Jonathan M. Silver and
Zanvil A. Cohn Pinocytosis in Fibroblasts . . . . . . . 949
Barbara H. Gibbons and
I. R. Gibbons Properties of Flagellar ``Rigor Waves''
Formed by Abrupt Removal of Adenosine
Triphosphate from Actively Swimming Sea
Urchin Sperm . . . . . . . . . . . . . . 970
Walter L. Davis and
David B. P. Goodman and
Richard J. Schuster and
Howard Rasmussen and
James H. Martin Effects of Cytochalasin B on the
Response of Toad Urinary Bladder to
Vasopressin . . . . . . . . . . . . . . 986
Folkert Bode and
Hannelore Pockrandt-Hemstedt and
Karl Baumann and
Rolf Kinne Analysis of the Pinocytic Process in Rat
Kidney . . . . . . . . . . . . . . . . . 998
John Rannestad The Regeneration of Cilia in Partially
Deciliated \bionameTetrahymena . . . . . 1009
Arnljot Elgsaeter and
Daniel Branton Intramembrane Particle Aggregation in
Erythrocyte Ghosts . . . . . . . . . . . 1018
A. Amsterdam and
J. D. Jamieson Studies on Dispersed Pancreatic Exocrine
Cells . . . . . . . . . . . . . . . . . 1037
A. Amsterdam and
J. D. Jamieson Studies on Dispersed Pancreatic Exocrine
Cells . . . . . . . . . . . . . . . . . 1057
S. L. Palay and
S. Billings-Gagliardi and
V. Chan-Palay Neuronal Perikarya with Dispersed,
Single Ribosomes in the Visual Cortex of
Macaca Mulatta . . . . . . . . . . . . . 1074
Kiyoshi Kishi Electron Microscope Studies on
Puromycin-Induced Changes in Nerve Cells
of the Medulla Oblongata . . . . . . . . 1091
M. Clutter and
T. Brady and
V. Walbot and
I. Sussex Macromolecular Synthesis During Plant
Embryogeny . . . . . . . . . . . . . . . 1097